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Overview

ID MAG01775
Name HKD2_bin.14
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Methylomirabilota
Class Methylomirabilia
Order Methylomirabilales
Family 2-02-FULL-66-22
Genus 2-02-FULL-66-22
Species
Assembly information
Completeness (%) 89.72
Contamination (%) 4.07
GC content (%) 65.0
N50 (bp) 17,386
Genome size (bp) 4,012,404

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3561

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10054883_0 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 366.0
HKD2_k127_10054883_1 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 341.0
HKD2_k127_10054883_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 310.0
HKD2_k127_10054883_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 310.0
HKD2_k127_10054883_4 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000001969 269.0
HKD2_k127_10054883_5 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000002059 248.0
HKD2_k127_10054883_6 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HKD2_k127_10054883_7 COG0782 Transcription elongation factor - - - 0.000000001403 64.0
HKD2_k127_10054883_8 C2H2-type zinc finger K07376 - 2.7.11.12 0.00009637 49.0
HKD2_k127_10066299_0 4Fe-4S dicluster domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 332.0
HKD2_k127_10066299_1 PFAM FAD linked oxidase domain protein K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001257 297.0
HKD2_k127_10066299_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000001288 177.0
HKD2_k127_10075427_0 PFAM Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 353.0
HKD2_k127_10075427_1 'Xanthine and CO dehydrogenases maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 354.0
HKD2_k127_10075427_2 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 321.0
HKD2_k127_10075427_3 MobA-like NTP transferase domain K07141,K19190 - 1.1.1.328,2.7.7.76 0.0000000000000000000000000000000000000000000000000000003993 200.0
HKD2_k127_10075427_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000002762 195.0
HKD2_k127_10075427_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000335 183.0
HKD2_k127_100845_0 UvrD/REP helicase N-terminal domain K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 631.0
HKD2_k127_100845_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0000000000000000000000000000000000000000000000007305 184.0
HKD2_k127_1010_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0 1024.0
HKD2_k127_1010_1 P-loop ATPase protein family K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 2.946e-196 623.0
HKD2_k127_1010_10 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001483 241.0
HKD2_k127_1010_11 Short-chain dehydrogenase reductase sdr K00038 - 1.1.1.53 0.0000000000000000000000000000000000000000000000000000000000003011 220.0
HKD2_k127_1010_12 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000001365 214.0
HKD2_k127_1010_13 COGs COG4293 conserved - - - 0.00000000000000000000000000000000000000000000001935 179.0
HKD2_k127_1010_14 cellulose binding K01179 - 3.2.1.4 0.0000000000000000007469 101.0
HKD2_k127_1010_16 Amidohydrolase K07045 - - 0.000946 51.0
HKD2_k127_1010_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 586.0
HKD2_k127_1010_3 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 467.0
HKD2_k127_1010_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 404.0
HKD2_k127_1010_5 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 365.0
HKD2_k127_1010_6 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 355.0
HKD2_k127_1010_7 Peptidase dimerisation domain K01439,K05831 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 329.0
HKD2_k127_1010_8 TIGRFAM RHS repeat-associated core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 326.0
HKD2_k127_1010_9 Enoyl-CoA hydratase/isomerase K13767 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000004478 268.0
HKD2_k127_10103899_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 8.231e-284 878.0
HKD2_k127_10103899_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 364.0
HKD2_k127_10103899_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000003974 262.0
HKD2_k127_10103899_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000001346 182.0
HKD2_k127_10103899_4 ABC transporter K02021,K06147,K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000002385 167.0
HKD2_k127_111326_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 1.223e-242 767.0
HKD2_k127_111326_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 550.0
HKD2_k127_111326_10 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 338.0
HKD2_k127_111326_11 Aldose 1-epimerase K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 314.0
HKD2_k127_111326_12 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000785 299.0
HKD2_k127_111326_13 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007543 278.0
HKD2_k127_111326_14 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000001388 218.0
HKD2_k127_111326_15 OmpA family K03640 - - 0.000000000000000000000000000000000000000000000000181 183.0
HKD2_k127_111326_16 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000001361 167.0
HKD2_k127_111326_17 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000001173 169.0
HKD2_k127_111326_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000003739 93.0
HKD2_k127_111326_19 - - - - 0.00000000000000005664 88.0
HKD2_k127_111326_2 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 521.0
HKD2_k127_111326_20 DUF218 domain - - - 0.000000000000002254 85.0
HKD2_k127_111326_21 Phosphorylase superfamily K01243 - 3.2.2.9 0.0000000000008847 78.0
HKD2_k127_111326_3 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 470.0
HKD2_k127_111326_4 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 448.0
HKD2_k127_111326_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 411.0
HKD2_k127_111326_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 408.0
HKD2_k127_111326_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 377.0
HKD2_k127_111326_8 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 369.0
HKD2_k127_111326_9 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 353.0
HKD2_k127_1131906_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02407,K02492,K10714 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 454.0
HKD2_k127_1131906_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000089 244.0
HKD2_k127_1131906_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000001026 226.0
HKD2_k127_1131906_3 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000004738 176.0
HKD2_k127_1308347_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1150.0
HKD2_k127_1308347_1 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 359.0
HKD2_k127_1308347_2 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 287.0
HKD2_k127_1308347_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000002377 202.0
HKD2_k127_1308347_4 - - - - 0.0000000000000000000000000000000005931 142.0
HKD2_k127_1308347_5 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000002358 99.0
HKD2_k127_1311713_0 lipopolysaccharide transport K22110 - - 0.0 1313.0
HKD2_k127_1311713_1 choline dehydrogenase activity - - - 1.487e-252 793.0
HKD2_k127_1311713_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000001105 72.0
HKD2_k127_1311713_11 Tetratricopeptide repeat - - - 0.00000002468 65.0
HKD2_k127_1311713_12 - - - - 0.00000007717 57.0
HKD2_k127_1311713_14 AntiSigma factor - - - 0.000004442 53.0
HKD2_k127_1311713_2 transcription factor binding K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 530.0
HKD2_k127_1311713_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 378.0
HKD2_k127_1311713_4 with different specificities (related to short-chain alcohol K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 374.0
HKD2_k127_1311713_5 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 337.0
HKD2_k127_1311713_6 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003332 246.0
HKD2_k127_1311713_7 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000414 188.0
HKD2_k127_1311713_8 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000001668 164.0
HKD2_k127_1311713_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000001314 143.0
HKD2_k127_1317610_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 355.0
HKD2_k127_1317610_1 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 308.0
HKD2_k127_1317610_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000271 254.0
HKD2_k127_1317610_3 DIM6 NTAB family - - - 0.0000000000000000000000000000000000000000000000004677 180.0
HKD2_k127_1317610_4 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000004986 118.0
HKD2_k127_1317610_5 spore germination K00442,K03605,K04656,K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.000000000000000000001595 106.0
HKD2_k127_1347821_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 584.0
HKD2_k127_1347821_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 518.0
HKD2_k127_1347821_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 314.0
HKD2_k127_1347821_3 - - - - 0.000000000000000000000000000000000000000000000000000006991 195.0
HKD2_k127_1347821_4 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000001201 112.0
HKD2_k127_1347821_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000002404 122.0
HKD2_k127_1347821_6 uridine phosphorylase activity K00757 - 2.4.2.3 0.0000000000000856 73.0
HKD2_k127_1347821_7 E1-E2 ATPase K17686 - 3.6.3.54 0.000006235 58.0
HKD2_k127_1349016_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 378.0
HKD2_k127_1349016_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001941 276.0
HKD2_k127_1349016_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000001999 207.0
HKD2_k127_1349016_3 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000166 187.0
HKD2_k127_1367393_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 576.0
HKD2_k127_1367393_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 373.0
HKD2_k127_1367393_2 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000000000000000000000000006815 138.0
HKD2_k127_1367393_3 helix_turn_helix isocitrate lyase regulation - - - 0.00000004449 59.0
HKD2_k127_1399069_0 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 608.0
HKD2_k127_1399069_1 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 346.0
HKD2_k127_1399069_2 Proteasome subunit K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 315.0
HKD2_k127_1399069_3 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.00000000000000000000000000000000000000000000000000000000000001069 218.0
HKD2_k127_140415_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000001929 278.0
HKD2_k127_140415_1 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001675 249.0
HKD2_k127_140415_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000002031 83.0
HKD2_k127_1420547_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 436.0
HKD2_k127_1420547_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 329.0
HKD2_k127_1420547_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001195 270.0
HKD2_k127_1420547_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000124 226.0
HKD2_k127_1424190_0 Hydantoinase/oxoprolinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 351.0
HKD2_k127_1424190_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000176 267.0
HKD2_k127_1424190_2 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000005634 248.0
HKD2_k127_1424190_3 peptidase S1 and S6, chymotrypsin Hap K04691,K04772 - - 0.00009516 52.0
HKD2_k127_1431649_0 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 471.0
HKD2_k127_1431649_1 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000001195 235.0
HKD2_k127_1431649_2 PFAM Radical SAM domain protein K22226 - - 0.000000000000000000000000000000000000000000006742 162.0
HKD2_k127_1433712_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - 2.364e-232 732.0
HKD2_k127_1433712_1 Efflux ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000131 219.0
HKD2_k127_1433712_2 ATPases associated with a variety of cellular activities K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000001606 211.0
HKD2_k127_1433712_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000008732 136.0
HKD2_k127_1433712_4 ATP synthesis coupled electron transport K00342,K00343,K05568 - 1.6.5.3 0.000000000000000000000000000007447 123.0
HKD2_k127_1433712_5 Multisubunit Na H antiporter MnhC subunit K00340,K05567 - 1.6.5.3 0.0000000000000000000000005625 107.0
HKD2_k127_1433712_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000001574 87.0
HKD2_k127_1433712_7 Domain of unknown function (DUF4418) - - - 0.00000000004932 69.0
HKD2_k127_1441059_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 546.0
HKD2_k127_1441059_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 370.0
HKD2_k127_1441059_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000587 166.0
HKD2_k127_1441059_3 - - - - 0.00000001932 61.0
HKD2_k127_1469870_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1332.0
HKD2_k127_1469870_1 Psort location CytoplasmicMembrane, score K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 608.0
HKD2_k127_1469870_2 4-phosphoerythronate dehydrogenase activity K00058,K16133 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 309.0
HKD2_k127_1469870_3 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 298.0
HKD2_k127_1469870_4 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000003381 66.0
HKD2_k127_1469870_5 Tripartite tricarboxylate transporter TctB family - - - 0.00004449 52.0
HKD2_k127_147021_0 Oxidoreductase molybdopterin binding domain K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 486.0
HKD2_k127_147021_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 312.0
HKD2_k127_147021_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008906 249.0
HKD2_k127_147021_3 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000003132 217.0
HKD2_k127_1488151_0 Tripartite tricarboxylate transporter TctA family K07793 - - 3.408e-195 621.0
HKD2_k127_1488151_1 Coenzyme A transferase K01026 - 2.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 614.0
HKD2_k127_1488151_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000001107 95.0
HKD2_k127_1488151_11 Oxidoreductase - - - 0.0001075 47.0
HKD2_k127_1488151_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 470.0
HKD2_k127_1488151_3 Evidence 4 Homologs of previously reported genes of K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 355.0
HKD2_k127_1488151_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 291.0
HKD2_k127_1488151_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000002519 226.0
HKD2_k127_1488151_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000005919 223.0
HKD2_k127_1488151_7 2-dehydro-3-deoxy-phosphogluconate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000006277 177.0
HKD2_k127_1488151_8 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000002156 126.0
HKD2_k127_1488151_9 Cytidylate kinase-like family - - - 0.000000000000000000000002997 113.0
HKD2_k127_1502120_0 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 5.222e-194 621.0
HKD2_k127_1502120_1 Leucine-rich repeat (LRR) protein - - - 0.000000000000003238 83.0
HKD2_k127_1502120_2 - - - - 0.0000001764 57.0
HKD2_k127_1515006_0 coagulation factor 5 8 type - - - 0.0 1141.0
HKD2_k127_1515006_1 Glycosyl transferase family 21 K03669 - - 4.958e-304 955.0
HKD2_k127_1515006_10 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 344.0
HKD2_k127_1515006_11 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 334.0
HKD2_k127_1515006_12 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001135 287.0
HKD2_k127_1515006_13 Binding-protein-dependent transport system inner membrane component K02026,K10119 - - 0.000000000000000000000000000000000000000000000000000000000136 213.0
HKD2_k127_1515006_14 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000000000002226 148.0
HKD2_k127_1515006_15 GYD domain - - - 0.0000000000000000000000000000000006751 135.0
HKD2_k127_1515006_16 Lipocalin-like domain - - - 0.000000000000000000000000000000001936 141.0
HKD2_k127_1515006_17 peroxiredoxin activity K02199 - - 0.0000000000000003878 81.0
HKD2_k127_1515006_18 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.00000000000002253 74.0
HKD2_k127_1515006_19 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.0000000000009054 71.0
HKD2_k127_1515006_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 4.219e-219 687.0
HKD2_k127_1515006_20 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000002256 58.0
HKD2_k127_1515006_3 Protein conserved in bacteria - - - 3.176e-198 630.0
HKD2_k127_1515006_4 ABC transporter substrate-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 557.0
HKD2_k127_1515006_5 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 GO:0000271,GO:0005575,GO:0005623,GO:0005975,GO:0005976,GO:0006073,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009628,GO:0009987,GO:0016051,GO:0030288,GO:0030313,GO:0031975,GO:0033692,GO:0034637,GO:0034645,GO:0042597,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0051273,GO:0051274,GO:0071704,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 523.0
HKD2_k127_1515006_6 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 469.0
HKD2_k127_1515006_7 N-acetyl-gamma-glutamyl-phosphate reductase activity K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 455.0
HKD2_k127_1515006_8 ABC-type sugar transport systems, permease components K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 444.0
HKD2_k127_1515006_9 PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 428.0
HKD2_k127_1529747_0 Bacterial protein of unknown function (DUF853) K06915 - - 4.111e-215 677.0
HKD2_k127_1529747_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 7.292e-206 644.0
HKD2_k127_1529747_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 350.0
HKD2_k127_1529747_3 D-galactarate dehydratase altronate hydrolase domain protein K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 344.0
HKD2_k127_1529747_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006129 239.0
HKD2_k127_1529747_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000003329 156.0
HKD2_k127_1529747_6 KR domain K00038 - 1.1.1.53 0.00000000000000000000000000000004553 135.0
HKD2_k127_1529747_7 SAF K16849 - 4.2.1.7 0.00000000000000000000001372 104.0
HKD2_k127_1533033_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 574.0
HKD2_k127_1533033_1 D-galactarate dehydratase altronate hydrolase domain protein K16850 - 4.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 526.0
HKD2_k127_1533033_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K00895 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 506.0
HKD2_k127_1533033_3 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 411.0
HKD2_k127_1533033_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 419.0
HKD2_k127_1533033_5 Ion channel - - - 0.00000000000000000000000000000005811 136.0
HKD2_k127_1533033_6 SAF domain K16849 - 4.2.1.7 0.000000000000000000000000000323 117.0
HKD2_k127_1542845_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 8.878e-279 874.0
HKD2_k127_1542845_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 563.0
HKD2_k127_1542845_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 473.0
HKD2_k127_1542845_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 468.0
HKD2_k127_1542845_4 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 399.0
HKD2_k127_1542845_5 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002626 278.0
HKD2_k127_1542845_6 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000007396 146.0
HKD2_k127_1584757_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 344.0
HKD2_k127_1584757_1 Belongs to the PdxA family K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 295.0
HKD2_k127_1584757_2 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000008061 267.0
HKD2_k127_1584757_3 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000005259 237.0
HKD2_k127_1584757_4 Oxidoreductase family, C-terminal alpha beta domain K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000007251 211.0
HKD2_k127_1584757_5 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000001381 187.0
HKD2_k127_1584757_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000001942 188.0
HKD2_k127_1584757_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000007625 174.0
HKD2_k127_1584757_8 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000008479 84.0
HKD2_k127_1629730_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1309.0
HKD2_k127_1629730_1 NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit K05587 - 1.6.5.3 2.499e-268 833.0
HKD2_k127_1629730_10 ArgJ family K00620,K00930 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 390.0
HKD2_k127_1629730_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 358.0
HKD2_k127_1629730_12 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 333.0
HKD2_k127_1629730_13 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003991 267.0
HKD2_k127_1629730_14 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001557 245.0
HKD2_k127_1629730_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001154 250.0
HKD2_k127_1629730_16 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000008441 231.0
HKD2_k127_1629730_17 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001978 223.0
HKD2_k127_1629730_18 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000217 212.0
HKD2_k127_1629730_19 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000002076 193.0
HKD2_k127_1629730_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 2.778e-246 767.0
HKD2_k127_1629730_20 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001616 179.0
HKD2_k127_1629730_21 - - - - 0.00000000000000000000000003857 111.0
HKD2_k127_1629730_22 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000002361 95.0
HKD2_k127_1629730_23 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000001297 96.0
HKD2_k127_1629730_24 TIGRFAM hydrogenase maturation protease - - - 0.0000000000000001281 85.0
HKD2_k127_1629730_25 - - - - 0.00000000002616 72.0
HKD2_k127_1629730_3 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 3.219e-220 707.0
HKD2_k127_1629730_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 4.112e-200 636.0
HKD2_k127_1629730_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 439.0
HKD2_k127_1629730_6 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily K00145,K05829 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 422.0
HKD2_k127_1629730_7 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 428.0
HKD2_k127_1629730_8 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 399.0
HKD2_k127_1629730_9 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K05588 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 388.0
HKD2_k127_1655727_0 PFAM Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 452.0
HKD2_k127_1655727_1 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 337.0
HKD2_k127_1655727_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 333.0
HKD2_k127_1655727_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 354.0
HKD2_k127_1655727_4 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000001775 183.0
HKD2_k127_1655727_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000005917 174.0
HKD2_k127_1655727_6 Bacterial extracellular solute-binding protein K02027 - - 0.0006171 45.0
HKD2_k127_1668551_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 3.92e-198 639.0
HKD2_k127_1668551_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 398.0
HKD2_k127_1683652_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 467.0
HKD2_k127_1683652_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 316.0
HKD2_k127_1683652_10 Protein of unknown function (DUF3096) - - - 0.00000001568 56.0
HKD2_k127_1683652_11 Belongs to the alpha-IPM synthase homocitrate synthase family K01649,K02594 - 2.3.3.13,2.3.3.14 0.000006736 51.0
HKD2_k127_1683652_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003181 267.0
HKD2_k127_1683652_3 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000414 185.0
HKD2_k127_1683652_4 PFAM 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000001212 166.0
HKD2_k127_1683652_6 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000001368 106.0
HKD2_k127_1683652_7 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.00000000000006562 78.0
HKD2_k127_1683652_8 - - - - 0.0000000004588 66.0
HKD2_k127_1683652_9 Protein of unknown function (DUF1328) - - - 0.000000001176 61.0
HKD2_k127_1695395_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 392.0
HKD2_k127_1695395_1 KR domain - - - 0.00000000000000000000000000000000000000000000002644 182.0
HKD2_k127_1695395_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000009681 92.0
HKD2_k127_1695395_3 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000003618 68.0
HKD2_k127_1712581_0 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 509.0
HKD2_k127_1712581_1 C4-dicarboxylate ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 473.0
HKD2_k127_1712581_10 FemAB family - - - 0.000000064 63.0
HKD2_k127_1712581_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 334.0
HKD2_k127_1712581_3 transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 306.0
HKD2_k127_1712581_4 Transketolase, central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004314 265.0
HKD2_k127_1712581_5 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003363 248.0
HKD2_k127_1712581_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000296 245.0
HKD2_k127_1712581_7 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000001424 140.0
HKD2_k127_1712581_8 Domain of unknown function (DUF4178) - - - 0.00000000000000001205 98.0
HKD2_k127_1712581_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000008378 87.0
HKD2_k127_1713315_0 Conserved carboxylase domain K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 569.0
HKD2_k127_1713315_1 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 488.0
HKD2_k127_1713315_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 327.0
HKD2_k127_1713315_3 coproporphyrinogen oxidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 320.0
HKD2_k127_1713315_4 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 248.0
HKD2_k127_1713315_5 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000002067 199.0
HKD2_k127_1713315_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000007929 162.0
HKD2_k127_1713315_7 glutaconyl-CoA decarboxylase subunit gamma K01615 - 4.1.1.70 0.000000000000004311 88.0
HKD2_k127_1713315_8 glutaconyl-CoA decarboxylase subunit gamma K01615 - 4.1.1.70 0.00000000000005596 84.0
HKD2_k127_1713315_9 DinB superfamily - - - 0.0000002405 55.0
HKD2_k127_173646_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1008.0
HKD2_k127_173646_1 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 528.0
HKD2_k127_173646_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 458.0
HKD2_k127_173646_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000398 178.0
HKD2_k127_1769278_0 Histidine kinase-like ATPases - - - 3.151e-299 954.0
HKD2_k127_1769278_1 PFAM FAD linked oxidase - - - 6.591e-252 782.0
HKD2_k127_1769278_10 DinB family - - - 0.0000000000000000000000000000000000000000000000000000003103 197.0
HKD2_k127_1769278_11 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000000001243 188.0
HKD2_k127_1769278_12 - - - - 0.0000000000000000000000000000000000000000000000001623 188.0
HKD2_k127_1769278_13 - - - - 0.0000000000000000000000000000128 130.0
HKD2_k127_1769278_14 - - - - 0.00000000000000000004888 95.0
HKD2_k127_1769278_15 Major Facilitator Superfamily - - - 0.00002073 48.0
HKD2_k127_1769278_2 Berberine and berberine like - - - 1.119e-245 766.0
HKD2_k127_1769278_3 amine dehydrogenase activity K17285 - - 7.926e-238 742.0
HKD2_k127_1769278_4 ATPase associated with various cellular activities, AAA_5 K02584 - - 2.481e-216 692.0
HKD2_k127_1769278_5 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 533.0
HKD2_k127_1769278_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520,K21739 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 457.0
HKD2_k127_1769278_7 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004606 266.0
HKD2_k127_1769278_8 PFAM ThiJ PfpI domain protein K18199 - 4.2.1.103 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
HKD2_k127_1769278_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004139 236.0
HKD2_k127_193746_0 Belongs to the PdxA family K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 413.0
HKD2_k127_193746_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 381.0
HKD2_k127_193746_2 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 301.0
HKD2_k127_193746_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000004907 210.0
HKD2_k127_1954457_0 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002973 263.0
HKD2_k127_1954457_1 PFAM Integrase core domain K07497 - - 0.00000000000000000000000006439 111.0
HKD2_k127_1954457_2 IMG reference gene - - - 0.000000000000001815 80.0
HKD2_k127_1954457_3 COG4584 Transposase and inactivated derivatives - - - 0.00000000565 63.0
HKD2_k127_2031717_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 406.0
HKD2_k127_2031717_1 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000007696 271.0
HKD2_k127_2031717_2 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000004841 216.0
HKD2_k127_2031717_3 Winged helix DNA-binding domain - - - 0.00000000000000000000000005274 114.0
HKD2_k127_2031717_4 Predicted permease K07089 - - 0.0000000000000000001464 89.0
HKD2_k127_2031717_5 PFAM Radical SAM domain protein - - - 0.0002224 46.0
HKD2_k127_2064163_0 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 1.46e-255 802.0
HKD2_k127_2064163_1 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 452.0
HKD2_k127_2064163_10 von Willebrand factor, type A - - - 0.00000000000000000000000000006411 127.0
HKD2_k127_2064163_11 conserved protein UCP033563 - - - 0.00000000000000000000000001367 115.0
HKD2_k127_2064163_12 Pup-like protein K13570 - - 0.00000000000001106 76.0
HKD2_k127_2064163_13 Regulatory protein, FmdB family - - - 0.00000000000004836 73.0
HKD2_k127_2064163_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 309.0
HKD2_k127_2064163_3 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000001149 263.0
HKD2_k127_2064163_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004384 263.0
HKD2_k127_2064163_5 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001039 228.0
HKD2_k127_2064163_6 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000004873 193.0
HKD2_k127_2064163_7 NUDIX domain - - - 0.0000000000000000000000000000000000000001956 156.0
HKD2_k127_2064163_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000002076 130.0
HKD2_k127_2064163_9 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000004949 127.0
HKD2_k127_2153475_0 acyl-CoA dehydrogenase activity K00249 - 1.3.8.7 0.0 1109.0
HKD2_k127_2153475_1 oxidoreductase K00311,K00313 - 1.5.5.1 1.567e-294 917.0
HKD2_k127_2153475_2 Transposase IS116/IS110/IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 482.0
HKD2_k127_2153475_3 electron transfer activity K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 413.0
HKD2_k127_2153475_4 TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 280.0
HKD2_k127_2153475_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000001002 242.0
HKD2_k127_2153475_6 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000002756 164.0
HKD2_k127_2185482_0 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 312.0
HKD2_k127_2185482_1 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000001646 212.0
HKD2_k127_2227559_0 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 327.0
HKD2_k127_2227559_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006205 265.0
HKD2_k127_2227559_2 Lipocalin-like domain - - - 0.00000000000000000000000000000009712 135.0
HKD2_k127_2227559_3 Lipocalin-like domain - - - 0.0000000000000001068 89.0
HKD2_k127_2227559_4 acetyltransferase K03826 - - 0.0000000000000004211 88.0
HKD2_k127_2254443_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1255.0
HKD2_k127_2254443_1 Ftsk_gamma K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 4.876e-219 705.0
HKD2_k127_2254443_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002776 287.0
HKD2_k127_2254443_11 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.000000000000000000000000000000000000000000000000000000000000000002205 239.0
HKD2_k127_2254443_12 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001185 237.0
HKD2_k127_2254443_13 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000006749 240.0
HKD2_k127_2254443_14 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000002601 181.0
HKD2_k127_2254443_15 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000004606 177.0
HKD2_k127_2254443_16 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000000008221 157.0
HKD2_k127_2254443_17 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000003103 119.0
HKD2_k127_2254443_18 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000374 110.0
HKD2_k127_2254443_19 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000782 117.0
HKD2_k127_2254443_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 2.534e-218 690.0
HKD2_k127_2254443_20 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000001291 89.0
HKD2_k127_2254443_3 B12 binding domain - - - 1.743e-196 633.0
HKD2_k127_2254443_4 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 610.0
HKD2_k127_2254443_5 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 499.0
HKD2_k127_2254443_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 439.0
HKD2_k127_2254443_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 401.0
HKD2_k127_2254443_8 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 376.0
HKD2_k127_2254443_9 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 364.0
HKD2_k127_2282626_0 Spermine/spermidine synthase domain - - - 1.471e-278 880.0
HKD2_k127_2282626_1 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 6.146e-215 677.0
HKD2_k127_2282626_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000008822 225.0
HKD2_k127_2282626_3 Type II secretory pathway, pseudopilin - - - 0.0000000000000000001386 97.0
HKD2_k127_2282626_4 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000009543 84.0
HKD2_k127_2288922_0 Cysteine-rich domain K11473,K21834 - - 2.67e-247 779.0
HKD2_k127_2288922_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652,K03852 - 2.2.1.6,2.3.3.15 7.605e-242 771.0
HKD2_k127_2288922_10 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 336.0
HKD2_k127_2288922_11 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 330.0
HKD2_k127_2288922_12 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 304.0
HKD2_k127_2288922_13 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000811 282.0
HKD2_k127_2288922_14 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001248 278.0
HKD2_k127_2288922_15 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001235 257.0
HKD2_k127_2288922_16 Dolichyl-phosphate-mannose-protein mannosyltransferase K00786 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000003146 244.0
HKD2_k127_2288922_17 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000003889 201.0
HKD2_k127_2288922_18 PFAM short chain dehydrogenase K00046,K00065,K18009 - 1.1.1.127,1.1.1.304,1.1.1.69,1.1.1.76 0.000000000000000000000000000000000000000000000000000000008844 213.0
HKD2_k127_2288922_19 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000005875 198.0
HKD2_k127_2288922_2 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 594.0
HKD2_k127_2288922_20 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000001513 169.0
HKD2_k127_2288922_21 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000002247 164.0
HKD2_k127_2288922_22 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000000000000006081 129.0
HKD2_k127_2288922_23 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000002161 120.0
HKD2_k127_2288922_24 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000003283 65.0
HKD2_k127_2288922_25 phosphorelay signal transduction system - - - 0.0000002051 59.0
HKD2_k127_2288922_3 Belongs to the GARS family K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 580.0
HKD2_k127_2288922_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 469.0
HKD2_k127_2288922_5 ThiF family K03148,K03636,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 430.0
HKD2_k127_2288922_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 408.0
HKD2_k127_2288922_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 379.0
HKD2_k127_2288922_8 TIGRFAM tripartite ATP-independent periplasmic transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 343.0
HKD2_k127_2288922_9 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 342.0
HKD2_k127_2312967_0 L-seryl-tRNA selenium transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 557.0
HKD2_k127_2312967_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 417.0
HKD2_k127_2312967_10 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000003327 179.0
HKD2_k127_2312967_11 methyltransferase - - - 0.000000000000000000000000000000000000009714 153.0
HKD2_k127_2312967_12 COGs COG4087 Soluble P-type ATPase - - - 0.0000000000000000000000000000000000000975 147.0
HKD2_k127_2312967_13 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000009142 138.0
HKD2_k127_2312967_14 Pfam Secreted repeat of K19519 - - 0.000000000000000000000000001665 119.0
HKD2_k127_2312967_15 - - - - 0.00000000000000000005728 96.0
HKD2_k127_2312967_16 TIGRFAM Protein of - - - 0.000000000000000005052 86.0
HKD2_k127_2312967_2 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 387.0
HKD2_k127_2312967_3 PFAM LOR SDH bifunctional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 393.0
HKD2_k127_2312967_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 380.0
HKD2_k127_2312967_5 ATPases associated with a variety of cellular activities K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 344.0
HKD2_k127_2312967_6 ABC transporter (Permease) K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
HKD2_k127_2312967_7 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002198 267.0
HKD2_k127_2312967_8 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003603 271.0
HKD2_k127_2312967_9 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000121 225.0
HKD2_k127_2351692_0 PFAM Aminotransferase class I and II K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 428.0
HKD2_k127_2351692_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003088 265.0
HKD2_k127_2351692_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000006301 81.0
HKD2_k127_2356164_0 Acyl-CoA synthetase (NDP forming) K09181 - - 6.528e-244 771.0
HKD2_k127_2356164_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 473.0
HKD2_k127_2356164_10 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000001254 197.0
HKD2_k127_2356164_11 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000002016 192.0
HKD2_k127_2356164_12 Universal stress protein family - - - 0.000000000000000000000000000000000000008364 150.0
HKD2_k127_2356164_13 protein tyrosine kinase activity - - - 0.00000000000000000000000000000000000009801 152.0
HKD2_k127_2356164_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000001163 133.0
HKD2_k127_2356164_15 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000006352 106.0
HKD2_k127_2356164_16 PFAM sigma-54 factor interaction domain-containing protein K07714 - - 0.000000000000000000007544 97.0
HKD2_k127_2356164_17 - K00176,K07138 - 1.2.7.3 0.0000000000000006994 80.0
HKD2_k127_2356164_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 460.0
HKD2_k127_2356164_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 421.0
HKD2_k127_2356164_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 362.0
HKD2_k127_2356164_5 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 349.0
HKD2_k127_2356164_6 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 295.0
HKD2_k127_2356164_7 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003507 271.0
HKD2_k127_2356164_8 DRTGG domain K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003938 278.0
HKD2_k127_2356164_9 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000007144 208.0
HKD2_k127_2559201_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 587.0
HKD2_k127_2559201_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 509.0
HKD2_k127_2559201_10 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000008746 130.0
HKD2_k127_2559201_11 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000002202 69.0
HKD2_k127_2559201_2 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 402.0
HKD2_k127_2559201_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 352.0
HKD2_k127_2559201_4 Belongs to the ABC transporter superfamily K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001098 300.0
HKD2_k127_2559201_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000357 243.0
HKD2_k127_2559201_6 molybdate ABC transporter, permease protein K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000003653 229.0
HKD2_k127_2559201_7 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000008861 222.0
HKD2_k127_2559201_8 glycolate biosynthetic process K01091,K06019 - 3.1.3.18,3.6.1.1 0.000000000000000000000000000000000000000000000000000000002659 209.0
HKD2_k127_2559201_9 RNA recognition motif - - - 0.0000000000000000000000000000000000000000009979 162.0
HKD2_k127_2562353_0 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 319.0
HKD2_k127_2562353_1 inositol 2-dehydrogenase activity K00010,K03810 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008156 287.0
HKD2_k127_2562353_10 FCD - - - 0.00000000000000000000000001041 117.0
HKD2_k127_2562353_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0000000000000000002133 94.0
HKD2_k127_2562353_2 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005195 252.0
HKD2_k127_2562353_3 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003885 238.0
HKD2_k127_2562353_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005088 227.0
HKD2_k127_2562353_5 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000001177 208.0
HKD2_k127_2562353_6 Binding-protein-dependent transport system inner membrane component K02026,K10229 - - 0.00000000000000000000000000000000000000000000000000237 201.0
HKD2_k127_2562353_7 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000002267 152.0
HKD2_k127_2562353_8 Dak1 domain K00863,K05878 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.00000000000000000000000000000001876 134.0
HKD2_k127_2562353_9 DinB superfamily - - - 0.000000000000000000000000000001837 126.0
HKD2_k127_2562866_0 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000001624 221.0
HKD2_k127_2562866_1 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000009 108.0
HKD2_k127_2562866_2 carboxymuconolactone decarboxylase - - - 0.0000000003685 64.0
HKD2_k127_2562866_3 Copper binding proteins, plastocyanin/azurin family - - - 0.000005413 55.0
HKD2_k127_2564257_0 Pfam:DUF162 - - - 9.837e-213 673.0
HKD2_k127_2564257_1 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 494.0
HKD2_k127_2564257_2 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 369.0
HKD2_k127_2564257_3 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
HKD2_k127_2564257_4 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000003619 119.0
HKD2_k127_2564257_5 methyltransferase activity - - - 0.000000003583 63.0
HKD2_k127_2579290_0 Beta-lactamase enzyme family K01286,K07258,K07262 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000007744 275.0
HKD2_k127_2579290_1 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000005406 202.0
HKD2_k127_2604377_0 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
HKD2_k127_2606175_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 2.943e-205 646.0
HKD2_k127_2606175_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 327.0
HKD2_k127_2606175_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001526 275.0
HKD2_k127_2606175_3 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001275 212.0
HKD2_k127_2606175_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000009566 95.0
HKD2_k127_2606175_5 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000003324 72.0
HKD2_k127_2619533_0 methyltransferase K20421 - 2.1.1.303 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 527.0
HKD2_k127_2636366_0 Domain of unknown function (DUF4070) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 500.0
HKD2_k127_2636366_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 464.0
HKD2_k127_2639559_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 433.0
HKD2_k127_2686700_0 - - - - 0.0000000000000000000000000000000000000002637 158.0
HKD2_k127_2686700_1 PFAM Resolvase - - - 0.00000000000000000001332 94.0
HKD2_k127_2686700_2 PFAM transposase IS66 - - - 0.00000065 51.0
HKD2_k127_2697731_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000002059 195.0
HKD2_k127_2731229_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 302.0
HKD2_k127_2731229_1 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 285.0
HKD2_k127_2731229_2 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003118 265.0
HKD2_k127_2731229_3 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004091 254.0
HKD2_k127_2731229_4 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000001898 105.0
HKD2_k127_2746346_0 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 460.0
HKD2_k127_2746346_1 serine-type endopeptidase activity K04772,K08372 - - 0.0000000000000000000000004554 109.0
HKD2_k127_2746346_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.0000000000000000005197 94.0
HKD2_k127_2746694_0 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 389.0
HKD2_k127_2746694_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 333.0
HKD2_k127_2746694_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 254.0
HKD2_k127_2746694_3 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000001694 240.0
HKD2_k127_2746694_4 Bacterial extracellular solute-binding protein K02027 - - 0.0000004941 56.0
HKD2_k127_2771971_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 574.0
HKD2_k127_2771971_1 Belongs to the 3-oxoacid CoA-transferase family K01026 - 2.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 558.0
HKD2_k127_2771971_10 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 353.0
HKD2_k127_2771971_11 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 349.0
HKD2_k127_2771971_12 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 307.0
HKD2_k127_2771971_13 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 294.0
HKD2_k127_2771971_14 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 303.0
HKD2_k127_2771971_15 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 291.0
HKD2_k127_2771971_16 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 288.0
HKD2_k127_2771971_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000001508 239.0
HKD2_k127_2771971_18 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000005752 229.0
HKD2_k127_2771971_19 Metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001397 220.0
HKD2_k127_2771971_2 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 507.0
HKD2_k127_2771971_20 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000001148 220.0
HKD2_k127_2771971_21 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000001645 183.0
HKD2_k127_2771971_22 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000001391 169.0
HKD2_k127_2771971_23 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000002209 163.0
HKD2_k127_2771971_24 transcriptional K03710 - - 0.00000000000000000000000000000000000000003218 161.0
HKD2_k127_2771971_25 Protein of unknown function (DUF1349) K09702 - - 0.000000000000000000000000000000000000001017 154.0
HKD2_k127_2771971_26 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000000000005694 133.0
HKD2_k127_2771971_27 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000001541 138.0
HKD2_k127_2771971_28 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000003559 109.0
HKD2_k127_2771971_29 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000007092 100.0
HKD2_k127_2771971_3 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 490.0
HKD2_k127_2771971_30 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.000000000000000000009358 99.0
HKD2_k127_2771971_31 photosystem II stabilization K02237,K02238 - - 0.00000003453 64.0
HKD2_k127_2771971_32 Ribbon-helix-helix protein, copG family - - - 0.0000001917 56.0
HKD2_k127_2771971_33 peptidyl-tyrosine sulfation - - - 0.00003995 50.0
HKD2_k127_2771971_4 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 460.0
HKD2_k127_2771971_5 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 411.0
HKD2_k127_2771971_6 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 397.0
HKD2_k127_2771971_7 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 408.0
HKD2_k127_2771971_8 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 374.0
HKD2_k127_2771971_9 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 359.0
HKD2_k127_2780873_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 602.0
HKD2_k127_2780873_1 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000002971 252.0
HKD2_k127_2780873_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0000000000000000000000000000000000000000000000000000002565 196.0
HKD2_k127_2780873_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000004358 107.0
HKD2_k127_2802208_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001733 267.0
HKD2_k127_2802208_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000001081 247.0
HKD2_k127_2835817_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner - - - 1.583e-309 968.0
HKD2_k127_2835817_1 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000000002313 142.0
HKD2_k127_2835817_2 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000002696 128.0
HKD2_k127_2835817_3 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000001764 122.0
HKD2_k127_2835817_4 KR domain K00059 - 1.1.1.100 0.0000000000001108 72.0
HKD2_k127_2850450_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 407.0
HKD2_k127_2850450_1 Protein export membrane protein K03296,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 342.0
HKD2_k127_2850450_2 Iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 349.0
HKD2_k127_2850450_3 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 313.0
HKD2_k127_2850450_4 alcohol dehydrogenase K00004 - 1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000003421 203.0
HKD2_k127_2850450_5 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000002571 117.0
HKD2_k127_2850450_6 membrane - - - 0.000000000003752 78.0
HKD2_k127_285058_0 dipeptide transport K02035 - - 6.815e-219 691.0
HKD2_k127_285058_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 597.0
HKD2_k127_285058_10 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000002827 53.0
HKD2_k127_285058_2 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 428.0
HKD2_k127_285058_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 413.0
HKD2_k127_285058_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 390.0
HKD2_k127_285058_5 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000000000000000000000000000008172 192.0
HKD2_k127_285058_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000007847 189.0
HKD2_k127_285058_8 - - - - 0.0000000000000001653 81.0
HKD2_k127_2889774_0 Phosphotransferase system HPr (HPr) family protein K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0 1025.0
HKD2_k127_2889774_1 Phosphotransferase System K02749,K02750,K02778,K02779,K02790,K02791,K02803,K02804 - 2.7.1.193,2.7.1.199,2.7.1.208 4.845e-232 733.0
HKD2_k127_2889774_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 3.416e-222 701.0
HKD2_k127_2889774_3 ATP-dependent DNA helicase K03657 - 3.6.4.12 7.292e-217 698.0
HKD2_k127_2889774_4 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 397.0
HKD2_k127_2889774_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000000000000000000000000000000006291 204.0
HKD2_k127_2889774_6 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000000008178 200.0
HKD2_k127_2889774_7 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000003974 176.0
HKD2_k127_2889774_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000004056 131.0
HKD2_k127_2896523_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 491.0
HKD2_k127_2896523_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 452.0
HKD2_k127_2896523_2 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 428.0
HKD2_k127_2896523_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 400.0
HKD2_k127_2896523_4 Binding-protein-dependent transport system inner membrane component K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 366.0
HKD2_k127_2896523_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 349.0
HKD2_k127_2896523_6 bacterial (prokaryotic) histone like domain K03530,K04764 - - 0.00000000000000000000000000000000000000211 148.0
HKD2_k127_2896523_7 Regulatory protein - - - 0.0000000000000000000000001043 111.0
HKD2_k127_2896523_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03749 - - 0.0002169 53.0
HKD2_k127_2923890_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 394.0
HKD2_k127_2923890_1 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 374.0
HKD2_k127_2923890_2 Uncharacterized conserved protein (DUF2249) K07322 - - 0.000000000000000000000000000000000000000000000000000002168 197.0
HKD2_k127_2923890_3 Transcriptional regulator K05799,K07746 - - 0.00000000000000000000000000000000002885 145.0
HKD2_k127_2959233_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 471.0
HKD2_k127_2959233_1 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 387.0
HKD2_k127_2959233_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 307.0
HKD2_k127_2959233_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000149 289.0
HKD2_k127_2959233_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001783 296.0
HKD2_k127_2959233_5 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002556 265.0
HKD2_k127_2959233_6 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001513 235.0
HKD2_k127_2959233_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000006666 173.0
HKD2_k127_2959233_8 Trap-type c4-dicarboxylate transport system, small permease component K11689,K21394 - - 0.00000000000003811 78.0
HKD2_k127_2959233_9 Asparaginase K13051 - 3.4.19.5 0.00000000001573 67.0
HKD2_k127_2972898_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1288.0
HKD2_k127_2972898_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 409.0
HKD2_k127_2972898_10 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 344.0
HKD2_k127_2972898_11 CoA-transferase family III K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 322.0
HKD2_k127_2972898_12 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 330.0
HKD2_k127_2972898_13 4-hydroxy-2-oxoglutarate aldolase K18123 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006081,GO:0006082,GO:0006090,GO:0006520,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008700,GO:0009056,GO:0009058,GO:0009063,GO:0009436,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0016833,GO:0019470,GO:0019471,GO:0019752,GO:0031974,GO:0032787,GO:0033609,GO:0042219,GO:0042802,GO:0042803,GO:0042866,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046185,GO:0046394,GO:0046395,GO:0046487,GO:0046983,GO:0070013,GO:0071704,GO:0072329,GO:0072330,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 307.0
HKD2_k127_2972898_14 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007007 289.0
HKD2_k127_2972898_15 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 280.0
HKD2_k127_2972898_16 Coenzyme A transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001158 278.0
HKD2_k127_2972898_17 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001637 281.0
HKD2_k127_2972898_18 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 267.0
HKD2_k127_2972898_19 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000003858 270.0
HKD2_k127_2972898_2 PFAM Transketolase K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 394.0
HKD2_k127_2972898_20 Coenzyme A transferase K01039 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004529 266.0
HKD2_k127_2972898_21 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005253 265.0
HKD2_k127_2972898_22 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01684 - 4.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000008244 265.0
HKD2_k127_2972898_23 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001206 253.0
HKD2_k127_2972898_24 ATPases associated with a variety of cellular activities K10545 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000007853 254.0
HKD2_k127_2972898_25 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002194 257.0
HKD2_k127_2972898_26 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004561 250.0
HKD2_k127_2972898_27 Periplasmic binding protein-like domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002347 249.0
HKD2_k127_2972898_28 Coenzyme A transferase K01039,K01040 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000001097 238.0
HKD2_k127_2972898_29 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000001528 230.0
HKD2_k127_2972898_3 Alcohol dehydrogenase zinc-binding domain protein K13953,K18382 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 357.0
HKD2_k127_2972898_30 Binding-protein-dependent transport system inner membrane component K02025,K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000328 228.0
HKD2_k127_2972898_31 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000001644 207.0
HKD2_k127_2972898_32 dehydratase - - - 0.000000000000000000000000000000000000000000000000000008515 202.0
HKD2_k127_2972898_33 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000005156 183.0
HKD2_k127_2972898_34 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000009147 176.0
HKD2_k127_2972898_35 - - - - 0.0000000000000000000000001756 110.0
HKD2_k127_2972898_36 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000004677 99.0
HKD2_k127_2972898_37 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.0000000000000000642 89.0
HKD2_k127_2972898_38 Bacterial extracellular solute-binding protein K02027,K17329 - - 0.00000000000009377 84.0
HKD2_k127_2972898_39 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000002304 77.0
HKD2_k127_2972898_4 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 345.0
HKD2_k127_2972898_40 CoA-transferase family III - - - 0.0000000001456 72.0
HKD2_k127_2972898_41 H( )-stimulated, divalent metal cation uptake system - - - 0.0000000006804 72.0
HKD2_k127_2972898_42 Uncharacterised protein family UPF0066 - - - 0.000000214 55.0
HKD2_k127_2972898_43 Uncharacterised protein family UPF0066 - - - 0.00005047 47.0
HKD2_k127_2972898_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 352.0
HKD2_k127_2972898_6 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 349.0
HKD2_k127_2972898_7 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 347.0
HKD2_k127_2972898_8 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 336.0
HKD2_k127_2972898_9 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 324.0
HKD2_k127_2992240_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.215e-203 644.0
HKD2_k127_2992240_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 412.0
HKD2_k127_2992240_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 378.0
HKD2_k127_2992240_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 367.0
HKD2_k127_2992240_4 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 316.0
HKD2_k127_2992240_5 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 282.0
HKD2_k127_2992240_6 ABC transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003553 263.0
HKD2_k127_3005995_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 5.932e-292 904.0
HKD2_k127_3005995_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.857e-215 682.0
HKD2_k127_3005995_10 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 388.0
HKD2_k127_3005995_11 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 406.0
HKD2_k127_3005995_12 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 394.0
HKD2_k127_3005995_13 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 345.0
HKD2_k127_3005995_14 Queuosine biosynthesis protein K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 362.0
HKD2_k127_3005995_15 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 293.0
HKD2_k127_3005995_16 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002345 284.0
HKD2_k127_3005995_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006014 254.0
HKD2_k127_3005995_18 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000002983 228.0
HKD2_k127_3005995_19 PFAM Stage II sporulation K06381 - - 0.000000000000000000000000000000000000000000000000000000000004 226.0
HKD2_k127_3005995_2 cellulose binding - - - 1.076e-212 666.0
HKD2_k127_3005995_20 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000001267 186.0
HKD2_k127_3005995_21 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000001105 173.0
HKD2_k127_3005995_22 YCII-related domain - - - 0.00000000000000000000000000000000000000000005365 161.0
HKD2_k127_3005995_23 Glycerol-3-phosphate responsive antiterminator K02443 - - 0.00000000000000000000000000000000000000000008943 167.0
HKD2_k127_3005995_24 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000001334 149.0
HKD2_k127_3005995_25 protein SCO1 SenC K07152 - - 0.000000000000000000000000002199 123.0
HKD2_k127_3005995_26 Protein of unknown function (DUF2905) - - - 0.000000000000000000000009275 103.0
HKD2_k127_3005995_27 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000002154 98.0
HKD2_k127_3005995_28 methyltransferase - - - 0.0000000000004664 78.0
HKD2_k127_3005995_29 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.000877 44.0
HKD2_k127_3005995_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 604.0
HKD2_k127_3005995_4 Bacterial extracellular solute-binding protein K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 605.0
HKD2_k127_3005995_5 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 526.0
HKD2_k127_3005995_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 512.0
HKD2_k127_3005995_7 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 467.0
HKD2_k127_3005995_8 Binding-protein-dependent transport system inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 426.0
HKD2_k127_3005995_9 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 413.0
HKD2_k127_3006679_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 558.0
HKD2_k127_3006679_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 471.0
HKD2_k127_3006679_2 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 348.0
HKD2_k127_3006679_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 293.0
HKD2_k127_3006679_4 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 281.0
HKD2_k127_3006679_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000002181 160.0
HKD2_k127_3006679_6 Lipocalin-like domain - - - 0.00000000000000000000000000000000000005483 147.0
HKD2_k127_301178_0 regulation of DNA-templated transcription, elongation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 631.0
HKD2_k127_301178_1 - - - - 0.000000000000000000000000000000363 129.0
HKD2_k127_3082262_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.259e-240 752.0
HKD2_k127_3082262_1 ligase activity, forming carbon-carbon bonds K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.000000000000000000000003263 104.0
HKD2_k127_310814_0 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 401.0
HKD2_k127_315763_0 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003737 262.0
HKD2_k127_315763_1 Glucose inhibited division protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000002765 243.0
HKD2_k127_315763_2 PFAM 4Fe-4S - - - 0.00000000000000000000000000000001458 141.0
HKD2_k127_3207942_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.271e-201 644.0
HKD2_k127_3207942_1 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 395.0
HKD2_k127_3207942_10 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00008238 49.0
HKD2_k127_3207942_2 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 340.0
HKD2_k127_3207942_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 303.0
HKD2_k127_3207942_4 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 303.0
HKD2_k127_3207942_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
HKD2_k127_3207942_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002613 272.0
HKD2_k127_3207942_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000148 216.0
HKD2_k127_3207942_8 carbohydrate transport K02025,K02027,K10118 - - 0.000000000000000000000000001158 128.0
HKD2_k127_3207942_9 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000004573 115.0
HKD2_k127_3216104_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 3.022e-195 620.0
HKD2_k127_3216104_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 433.0
HKD2_k127_3216104_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000005536 98.0
HKD2_k127_3216104_11 Malate/L-lactate dehydrogenase - - - 0.0000000001906 64.0
HKD2_k127_3216104_2 PFAM Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 411.0
HKD2_k127_3216104_3 Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 383.0
HKD2_k127_3216104_4 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002073 240.0
HKD2_k127_3216104_5 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000007528 231.0
HKD2_k127_3216104_6 TRAP-type C4-dicarboxylate transport system, periplasmic K11688 - - 0.0000000000000000000000000000000000000000000000000000000000003174 224.0
HKD2_k127_3216104_7 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000003439 183.0
HKD2_k127_3216104_8 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000001493 152.0
HKD2_k127_3216104_9 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000004887 110.0
HKD2_k127_3259323_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 298.0
HKD2_k127_3259323_1 May be involved in the transport of PQQ or its precursor to the periplasm K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001376 274.0
HKD2_k127_3259323_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.0000000000000000000001834 99.0
HKD2_k127_3259323_3 TIGRFAM dihydroxyacetone kinase, L subunit K05879 - 2.7.1.121 0.000008183 49.0
HKD2_k127_328829_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1834.0
HKD2_k127_328829_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 464.0
HKD2_k127_328829_2 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 319.0
HKD2_k127_328829_3 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000001108 166.0
HKD2_k127_328829_4 - - - - 0.0000000000000000000000000000000006592 132.0
HKD2_k127_328829_5 SEC-C Motif Domain Protein - - - 0.00000000000000000000000008399 126.0
HKD2_k127_328829_6 Thioredoxin domain - - - 0.00000000000000000003827 91.0
HKD2_k127_328829_7 deoxyhypusine monooxygenase activity K03070,K05385 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000126 102.0
HKD2_k127_328829_8 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000005576 85.0
HKD2_k127_328829_9 - - - - 0.0000000000000001258 84.0
HKD2_k127_3305324_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.069e-289 899.0
HKD2_k127_3305324_1 SMART Nucleotide binding protein, PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 465.0
HKD2_k127_335328_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1394.0
HKD2_k127_335328_1 pfkB family carbohydrate kinase K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 457.0
HKD2_k127_335328_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 440.0
HKD2_k127_335328_3 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003106 248.0
HKD2_k127_335328_4 Domain of unknown function (DUF4388) K03413 - - 0.00000000000000000000000000000000000000001107 169.0
HKD2_k127_335328_5 Domain of unknown function (DUF4388) K03413 - - 0.00000000000000000000000000000000000000004683 168.0
HKD2_k127_335328_6 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000005133 107.0
HKD2_k127_335328_7 - - - - 0.0000000001231 67.0
HKD2_k127_335328_8 - - - - 0.000000004176 66.0
HKD2_k127_3398762_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003528 278.0
HKD2_k127_3398762_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009002 258.0
HKD2_k127_3398762_2 ABC transporter substrate binding protein K01989 - - 0.0000000000009899 68.0
HKD2_k127_3445857_0 - - - - 0.000000000001273 72.0
HKD2_k127_3445857_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.00002997 47.0
HKD2_k127_3462184_0 Transglycosylase K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 3.344e-277 873.0
HKD2_k127_3462184_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.34e-238 764.0
HKD2_k127_3462184_10 - - - - 0.000000000001281 69.0
HKD2_k127_3462184_11 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000001746 66.0
HKD2_k127_3462184_2 Endoribonuclease that initiates mRNA decay K05802,K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 550.0
HKD2_k127_3462184_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 482.0
HKD2_k127_3462184_4 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 445.0
HKD2_k127_3462184_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 418.0
HKD2_k127_3462184_6 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 321.0
HKD2_k127_3462184_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 328.0
HKD2_k127_3462184_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000005876 171.0
HKD2_k127_3462184_9 O-methyltransferase - - - 0.0000000000000000000000000000001104 133.0
HKD2_k127_3552394_0 - - - - 0.000000000000000000000000000000000000000000000000003628 186.0
HKD2_k127_3552394_1 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000001278 155.0
HKD2_k127_3552394_10 Belongs to the 'phage' integrase family - - - 0.0000005783 57.0
HKD2_k127_3552394_11 Belongs to the Nudix hydrolase family - - - 0.000002982 55.0
HKD2_k127_3552394_2 Phage capsid family - - - 0.00000000000000000000006363 112.0
HKD2_k127_3552394_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000004533 100.0
HKD2_k127_3552394_4 Acetyltransferase (GNAT) domain K03817 - - 0.00000000000000000005605 93.0
HKD2_k127_3552394_5 Belongs to the 'phage' integrase family - - - 0.0000000000000003155 85.0
HKD2_k127_3552394_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000007512 61.0
HKD2_k127_3552394_9 Helix-turn-helix domain - - - 0.00000004277 57.0
HKD2_k127_3554961_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 580.0
HKD2_k127_3554961_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 546.0
HKD2_k127_3554961_2 cell septum assembly - - - 0.00000000000002481 82.0
HKD2_k127_3554961_3 Dienelactone hydrolase - - - 0.000002815 55.0
HKD2_k127_3554961_5 Chemotaxis protein CheY - - - 0.000006202 54.0
HKD2_k127_3555073_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.219e-286 888.0
HKD2_k127_3555073_1 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 362.0
HKD2_k127_3555073_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 323.0
HKD2_k127_3555073_3 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000001162 184.0
HKD2_k127_3600990_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 577.0
HKD2_k127_3600990_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 294.0
HKD2_k127_3600990_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000716 222.0
HKD2_k127_360584_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1335.0
HKD2_k127_360584_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.248e-241 759.0
HKD2_k127_360584_10 Transglycosylase SLT domain K08307,K12204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000882 284.0
HKD2_k127_360584_11 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000006279 214.0
HKD2_k127_360584_12 Phage integrase family - - - 0.00000000000209 73.0
HKD2_k127_360584_13 protein homooligomerization - - - 0.00000000001591 71.0
HKD2_k127_360584_14 TPR repeat - - - 0.0000000001175 72.0
HKD2_k127_360584_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 437.0
HKD2_k127_360584_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 414.0
HKD2_k127_360584_4 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 399.0
HKD2_k127_360584_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 359.0
HKD2_k127_360584_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 343.0
HKD2_k127_360584_7 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 336.0
HKD2_k127_360584_8 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 314.0
HKD2_k127_360584_9 D-isomer specific 2-hydroxyacid dehydrogenase K00015,K00018 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26,1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 302.0
HKD2_k127_3671862_0 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 403.0
HKD2_k127_3671862_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 357.0
HKD2_k127_3671862_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 296.0
HKD2_k127_3671862_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 307.0
HKD2_k127_3671862_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.00000000000000000000000000000000000000000000000003472 183.0
HKD2_k127_3671862_5 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000005767 173.0
HKD2_k127_3671862_6 ThiS family K03636 - - 0.00006766 51.0
HKD2_k127_3729235_0 L-fucose isomerase K01818 - 5.3.1.25,5.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 607.0
HKD2_k127_3729235_1 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 506.0
HKD2_k127_3729235_10 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008727 274.0
HKD2_k127_3729235_11 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000001206 198.0
HKD2_k127_3729235_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000001493 176.0
HKD2_k127_3729235_13 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000000002664 118.0
HKD2_k127_3729235_14 - - - - 0.0000000000000000000000001099 108.0
HKD2_k127_3729235_15 - - - - 0.0000000004357 69.0
HKD2_k127_3729235_2 Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 464.0
HKD2_k127_3729235_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 441.0
HKD2_k127_3729235_4 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 423.0
HKD2_k127_3729235_5 Belongs to the FGGY kinase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 405.0
HKD2_k127_3729235_6 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 350.0
HKD2_k127_3729235_7 ABC-type sugar transport system periplasmic component K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 344.0
HKD2_k127_3729235_8 Carbohydrate ABC transporter membrane protein 2, CUT1 family K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 306.0
HKD2_k127_3729235_9 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
HKD2_k127_379520_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 538.0
HKD2_k127_379520_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000001428 136.0
HKD2_k127_3796590_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 339.0
HKD2_k127_3796590_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 302.0
HKD2_k127_3796590_2 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000009774 219.0
HKD2_k127_3796590_3 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000004123 209.0
HKD2_k127_3796590_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000001169 201.0
HKD2_k127_3796590_5 COG4520 Surface antigen - - - 0.00000000000000000000000000000000000004049 149.0
HKD2_k127_3796590_6 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.0008077 46.0
HKD2_k127_3832700_0 Hpt domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 468.0
HKD2_k127_3832700_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 335.0
HKD2_k127_3833600_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1176.0
HKD2_k127_3833600_1 PFAM glycosyl transferase family 39 - - - 2.327e-219 720.0
HKD2_k127_3833600_10 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0040007,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 411.0
HKD2_k127_3833600_11 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 409.0
HKD2_k127_3833600_12 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 359.0
HKD2_k127_3833600_13 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 318.0
HKD2_k127_3833600_14 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002956 285.0
HKD2_k127_3833600_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000006668 215.0
HKD2_k127_3833600_16 GtrA-like protein - - - 0.00000000000000000000000000000000000000001232 178.0
HKD2_k127_3833600_17 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000149 156.0
HKD2_k127_3833600_18 - - - - 0.0000000000000000000000000000000000008297 148.0
HKD2_k127_3833600_19 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.000000983 56.0
HKD2_k127_3833600_2 PFAM Asparagine synthase K01953 - 6.3.5.4 5.317e-214 691.0
HKD2_k127_3833600_3 Protein involved in outer membrane biogenesis - - - 1.677e-213 701.0
HKD2_k127_3833600_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 569.0
HKD2_k127_3833600_5 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 556.0
HKD2_k127_3833600_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 515.0
HKD2_k127_3833600_7 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 464.0
HKD2_k127_3833600_8 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 457.0
HKD2_k127_3833600_9 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 454.0
HKD2_k127_3841348_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 432.0
HKD2_k127_3841348_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0000000000000000000000000000000000005641 153.0
HKD2_k127_3841348_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000002767 142.0
HKD2_k127_3841348_3 DEAD DEAH box helicase K06877 - - 0.00000000000000000000000000001706 124.0
HKD2_k127_3841348_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000008007 108.0
HKD2_k127_3841348_5 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000001372 105.0
HKD2_k127_3841348_6 - - - - 0.0000000000000000407 87.0
HKD2_k127_3845309_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000001995 227.0
HKD2_k127_3845309_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000005124 207.0
HKD2_k127_3845309_2 Belongs to the UPF0296 family K09777 - - 0.000000000000000000004241 93.0
HKD2_k127_3845309_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000001163 68.0
HKD2_k127_3848696_0 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007784 287.0
HKD2_k127_3848696_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000009174 191.0
HKD2_k127_3848696_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044464,GO:0055114 1.1.1.85 0.000000003096 59.0
HKD2_k127_3854752_0 peptidase S16 K01338,K04076,K04770,K16012,K16014 - 3.4.21.53 0.0 1095.0
HKD2_k127_3854752_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.94e-277 870.0
HKD2_k127_3854752_10 2Fe-2S -binding domain protein K18029 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016725,GO:0019439,GO:0044237,GO:0044248,GO:0055114 1.17.2.1 0.000000000000000000000000000000000000000000000000000000000002209 213.0
HKD2_k127_3854752_11 adenosine deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000003774 195.0
HKD2_k127_3854752_12 membrane - - - 0.000000000000000000000000000000000000000009528 160.0
HKD2_k127_3854752_14 - - - - 0.000000001458 69.0
HKD2_k127_3854752_15 Outer membrane lipoprotein carrier protein LolA - - - 0.000000001654 69.0
HKD2_k127_3854752_2 B12 binding domain - - - 1.48e-236 741.0
HKD2_k127_3854752_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 584.0
HKD2_k127_3854752_4 Radical SAM superfamily K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 555.0
HKD2_k127_3854752_5 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 413.0
HKD2_k127_3854752_6 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 414.0
HKD2_k127_3854752_7 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 314.0
HKD2_k127_3854752_8 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000003726 244.0
HKD2_k127_3854752_9 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000002867 225.0
HKD2_k127_3872558_0 Bacterial extracellular solute-binding protein K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 588.0
HKD2_k127_3872558_1 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 397.0
HKD2_k127_3872558_2 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 327.0
HKD2_k127_3872558_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000447 286.0
HKD2_k127_3872558_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000189 258.0
HKD2_k127_3872558_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000007454 246.0
HKD2_k127_3872558_6 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000003683 228.0
HKD2_k127_3872558_7 PIN domain - - - 0.000000000000000000000000007834 114.0
HKD2_k127_3872558_8 transmembrane transport K02025,K05814,K15771 - - 0.000000000000000001717 89.0
HKD2_k127_3872558_9 Amidohydrolase K07045 - - 0.0000000000000001725 90.0
HKD2_k127_3880786_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 463.0
HKD2_k127_3880786_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 335.0
HKD2_k127_3880786_2 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000002189 130.0
HKD2_k127_3880786_3 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000001542 72.0
HKD2_k127_3880786_4 Protein of unknown function (DUF2877) - - - 0.000000005111 62.0
HKD2_k127_3890475_0 transport systems, ATPase components K02056 - 3.6.3.17 1.58e-204 650.0
HKD2_k127_3890475_1 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 516.0
HKD2_k127_3890475_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 448.0
HKD2_k127_3890475_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 385.0
HKD2_k127_3890475_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 359.0
HKD2_k127_3890475_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 303.0
HKD2_k127_3890475_6 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000002204 113.0
HKD2_k127_3890475_7 Trypsin-like peptidase domain K08372 - - 0.0008467 51.0
HKD2_k127_3892089_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 6.747e-267 834.0
HKD2_k127_3892089_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
HKD2_k127_3892089_10 Resolvase, N terminal domain - - - 0.0000000000000001747 92.0
HKD2_k127_3892089_11 ABC transporter K02068 - - 0.00000000000000214 82.0
HKD2_k127_3892089_12 Resolvase, N terminal domain - - - 0.00000000248 62.0
HKD2_k127_3892089_13 Cupin 2 conserved barrel domain protein - - - 0.0000004819 59.0
HKD2_k127_3892089_14 PFAM TPR repeat-containing protein - - - 0.00001661 47.0
HKD2_k127_3892089_15 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0004021 47.0
HKD2_k127_3892089_2 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000007535 224.0
HKD2_k127_3892089_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000002941 226.0
HKD2_k127_3892089_5 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000008771 182.0
HKD2_k127_3892089_6 SMART Chromosomal replication initiator DnaA domain - - - 0.000000000000000000000000000000000000000002908 164.0
HKD2_k127_3892089_7 Hep Hag repeat protein - - - 0.0000000000000000000000000000000001195 150.0
HKD2_k127_3892089_8 - - - - 0.0000000000000000002434 93.0
HKD2_k127_3892089_9 Helix-turn-helix domain K07497 - - 0.00000000000000002303 86.0
HKD2_k127_3893938_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.487e-289 901.0
HKD2_k127_3893938_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 5.405e-232 730.0
HKD2_k127_3893938_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001753 292.0
HKD2_k127_3893938_11 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009968 277.0
HKD2_k127_3893938_12 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002036 280.0
HKD2_k127_3893938_13 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009926 253.0
HKD2_k127_3893938_14 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000002016 241.0
HKD2_k127_3893938_15 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006788 237.0
HKD2_k127_3893938_16 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000001721 201.0
HKD2_k127_3893938_17 Guanylyl transferase CofC like K09931 - - 0.00000000000000000000000000000000000000000000001386 180.0
HKD2_k127_3893938_18 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000889 174.0
HKD2_k127_3893938_19 - K16937 - 1.8.5.2 0.000000000000000000000000000000000000000001439 162.0
HKD2_k127_3893938_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 412.0
HKD2_k127_3893938_20 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000005882 132.0
HKD2_k127_3893938_21 cheY-homologous receiver domain - - - 0.0000000000000926 79.0
HKD2_k127_3893938_3 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008093 364.0
HKD2_k127_3893938_4 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 342.0
HKD2_k127_3893938_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 331.0
HKD2_k127_3893938_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 330.0
HKD2_k127_3893938_7 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 314.0
HKD2_k127_3893938_8 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 309.0
HKD2_k127_3893938_9 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001326 285.0
HKD2_k127_3909881_0 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 4.157e-197 623.0
HKD2_k127_3909881_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 608.0
HKD2_k127_3909881_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 468.0
HKD2_k127_3909881_11 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 459.0
HKD2_k127_3909881_12 Belongs to the D-alanine--D-alanine ligase family K01921,K01924 - 6.3.2.4,6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 454.0
HKD2_k127_3909881_13 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 418.0
HKD2_k127_3909881_14 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 373.0
HKD2_k127_3909881_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 344.0
HKD2_k127_3909881_16 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215,K03546 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 328.0
HKD2_k127_3909881_17 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 309.0
HKD2_k127_3909881_18 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 302.0
HKD2_k127_3909881_19 Deoxynucleoside kinase K15518 - 2.7.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 296.0
HKD2_k127_3909881_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 580.0
HKD2_k127_3909881_20 Cell wall formation K00075,K01921 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0022603,GO:0022604,GO:0030203,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0055114,GO:0065007,GO:0065008,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
HKD2_k127_3909881_21 Alpha/beta hydrolase family K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 266.0
HKD2_k127_3909881_22 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000000000000000000000000000000003356 198.0
HKD2_k127_3909881_23 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000001407 186.0
HKD2_k127_3909881_24 Essential cell division protein K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000002514 174.0
HKD2_k127_3909881_25 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000000000000000000000000000000002253 152.0
HKD2_k127_3909881_26 Protein of unknown function (DUF4019) - - - 0.00000000000000000000000000000000005208 139.0
HKD2_k127_3909881_27 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000004035 133.0
HKD2_k127_3909881_28 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000007798 136.0
HKD2_k127_3909881_29 Transposase IS200 like - - - 0.00000000000000000000000000000001529 133.0
HKD2_k127_3909881_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 564.0
HKD2_k127_3909881_30 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000001268 120.0
HKD2_k127_3909881_31 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000001942 83.0
HKD2_k127_3909881_32 STAS domain - - - 0.00007285 51.0
HKD2_k127_3909881_4 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases K18369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 544.0
HKD2_k127_3909881_5 Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 541.0
HKD2_k127_3909881_6 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928,K03587,K15792 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.4.16.4,6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 548.0
HKD2_k127_3909881_7 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 505.0
HKD2_k127_3909881_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 480.0
HKD2_k127_3909881_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 467.0
HKD2_k127_3914347_0 formate dehydrogenase, alpha subunit K00123,K00370,K08356 - 1.17.1.9,1.20.2.1,1.20.9.1,1.7.5.1 0.0 1205.0
HKD2_k127_3914347_1 COG5659 FOG Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 419.0
HKD2_k127_3914347_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008263 261.0
HKD2_k127_3914347_3 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000007242 223.0
HKD2_k127_3914347_4 thiamine pyrophosphate protein TPP binding domain protein K00156,K00158 - 1.2.3.3,1.2.5.1 0.00000000000000000000000000000000000000000000000000002262 205.0
HKD2_k127_3914347_5 iron dependent repressor K02003,K02565,K15545 - - 0.0000000000000005648 79.0
HKD2_k127_3914551_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 555.0
HKD2_k127_3914551_1 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 428.0
HKD2_k127_3914551_10 Sugar ABC transporter permease K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008583 247.0
HKD2_k127_3914551_11 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000003525 240.0
HKD2_k127_3914551_12 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000004654 228.0
HKD2_k127_3914551_13 Alginate lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000002605 237.0
HKD2_k127_3914551_14 PFAM Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000002543 227.0
HKD2_k127_3914551_15 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000002871 212.0
HKD2_k127_3914551_16 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000001369 192.0
HKD2_k127_3914551_17 COG0500 SAM-dependent methyltransferases K17462 - - 0.00000000000000000000000000000000000000000000000003823 192.0
HKD2_k127_3914551_18 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000006029 160.0
HKD2_k127_3914551_19 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.0000000000000000000000000000000000001617 150.0
HKD2_k127_3914551_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 412.0
HKD2_k127_3914551_20 Putative cyclase - - - 0.0000000000000000000000000000000001514 142.0
HKD2_k127_3914551_21 PFAM methyltransferase - - - 0.00000000000000000000000000000526 131.0
HKD2_k127_3914551_22 gas vesicle protein - - - 0.00000000000000000000000000003846 121.0
HKD2_k127_3914551_23 DsrE/DsrF-like family - - - 0.00000000000000006219 91.0
HKD2_k127_3914551_24 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000008819 89.0
HKD2_k127_3914551_25 nucleotidyltransferase activity - - - 0.000000000001211 78.0
HKD2_k127_3914551_26 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000001507 74.0
HKD2_k127_3914551_27 - - - - 0.00000000003386 68.0
HKD2_k127_3914551_28 Psort location Cytoplasmic, score - - - 0.00001612 52.0
HKD2_k127_3914551_3 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 407.0
HKD2_k127_3914551_4 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 392.0
HKD2_k127_3914551_5 Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 379.0
HKD2_k127_3914551_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 359.0
HKD2_k127_3914551_7 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 364.0
HKD2_k127_3914551_8 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004632 289.0
HKD2_k127_3914551_9 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001861 283.0
HKD2_k127_3936096_0 GTP-binding protein TypA K06207 - - 2.393e-264 825.0
HKD2_k127_3936096_1 Helix-hairpin-helix containing domain K03581 - 3.1.11.5 1.562e-257 814.0
HKD2_k127_3936096_10 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 301.0
HKD2_k127_3936096_11 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 298.0
HKD2_k127_3936096_12 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001906 262.0
HKD2_k127_3936096_13 methyltransferase activity K17462 - - 0.00000000000000000000000000000000000000000000000000000000000000000004965 239.0
HKD2_k127_3936096_14 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
HKD2_k127_3936096_15 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000005412 231.0
HKD2_k127_3936096_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000435 120.0
HKD2_k127_3936096_17 haloacid dehalogenase-like hydrolase K06019 - 3.6.1.1 0.00000000000000000000001864 109.0
HKD2_k127_3936096_18 - - - - 0.00000000000000000002906 93.0
HKD2_k127_3936096_19 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.000000000000002736 85.0
HKD2_k127_3936096_2 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 570.0
HKD2_k127_3936096_20 Pilus assembly protein PilX - - - 0.0000000000001119 84.0
HKD2_k127_3936096_3 PFAM Cys Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 524.0
HKD2_k127_3936096_4 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 528.0
HKD2_k127_3936096_5 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 451.0
HKD2_k127_3936096_6 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 430.0
HKD2_k127_3936096_7 Carbon-nitrogen hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 427.0
HKD2_k127_3936096_8 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K07106,K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170,4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 411.0
HKD2_k127_3936096_9 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 327.0
HKD2_k127_3947418_0 DEAD DEAH box K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 535.0
HKD2_k127_3947418_1 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000000554 146.0
HKD2_k127_3947418_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000003918 94.0
HKD2_k127_3947418_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000399 85.0
HKD2_k127_3948393_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 294.0
HKD2_k127_3948393_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002547 252.0
HKD2_k127_3948393_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000003201 188.0
HKD2_k127_3989112_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 375.0
HKD2_k127_3989112_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 343.0
HKD2_k127_3989112_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000003396 171.0
HKD2_k127_3989112_3 PIN domain - - - 0.0000000000000000000000000000000001337 137.0
HKD2_k127_3989112_4 positive regulation of growth - - - 0.00000000000000000005144 93.0
HKD2_k127_3989112_5 Family of unknown function (DUF1028) - - - 0.000000000000000003202 86.0
HKD2_k127_3993144_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 442.0
HKD2_k127_3993144_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001913 285.0
HKD2_k127_3993144_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000002644 256.0
HKD2_k127_3993144_4 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000569 94.0
HKD2_k127_3997182_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 479.0
HKD2_k127_3997182_1 SAM-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 405.0
HKD2_k127_3997182_2 ABC transporter K06147,K18890 - - 0.00000000000000000307 85.0
HKD2_k127_3997182_3 Predicted membrane protein (DUF2157) - - - 0.0000000815 54.0
HKD2_k127_3998216_0 amino acid - - - 8.742e-263 820.0
HKD2_k127_3998216_1 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 344.0
HKD2_k127_3998216_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 295.0
HKD2_k127_3998216_3 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001903 291.0
HKD2_k127_3998216_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000005582 234.0
HKD2_k127_3998216_5 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000001987 226.0
HKD2_k127_3998216_6 transcriptional K03710 - - 0.000000000000000000000000000000000000001262 158.0
HKD2_k127_4004772_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1350.0
HKD2_k127_4004772_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain K06445 - - 1.268e-320 1000.0
HKD2_k127_4004772_10 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 322.0
HKD2_k127_4004772_11 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 317.0
HKD2_k127_4004772_12 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 316.0
HKD2_k127_4004772_13 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
HKD2_k127_4004772_14 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01003,K01841 - 4.1.1.3,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
HKD2_k127_4004772_15 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000001212 118.0
HKD2_k127_4004772_16 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000004851 113.0
HKD2_k127_4004772_17 TOBE domain - - - 0.00000000000000000001411 96.0
HKD2_k127_4004772_2 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 2.25e-240 760.0
HKD2_k127_4004772_3 2-methylcitrate dehydratase K01720 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0047547,GO:0071704 4.2.1.79 7.446e-209 664.0
HKD2_k127_4004772_4 Citrate synthase, C-terminal domain K01659 - 2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 482.0
HKD2_k127_4004772_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 470.0
HKD2_k127_4004772_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 447.0
HKD2_k127_4004772_7 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 420.0
HKD2_k127_4004772_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 353.0
HKD2_k127_4004772_9 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 335.0
HKD2_k127_4005256_0 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 407.0
HKD2_k127_4005256_1 mevalonate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 381.0
HKD2_k127_4005256_2 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 330.0
HKD2_k127_4005256_3 MobA-like NTP transferase domain K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 329.0
HKD2_k127_4005256_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 302.0
HKD2_k127_4005256_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000001865 272.0
HKD2_k127_4005256_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
HKD2_k127_4005256_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000004469 193.0
HKD2_k127_4005256_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000004374 129.0
HKD2_k127_4005256_9 SMART Water Stress and Hypersensitive response - - - 0.000000000000000000000002437 108.0
HKD2_k127_4033038_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 556.0
HKD2_k127_4033038_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 432.0
HKD2_k127_4033038_2 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 387.0
HKD2_k127_4033038_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
HKD2_k127_4033038_4 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 325.0
HKD2_k127_4033038_5 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005461 273.0
HKD2_k127_4033038_6 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000006347 109.0
HKD2_k127_4033038_7 PFAM ABC transporter related K10112 - - 0.000000000000000000353 88.0
HKD2_k127_4033038_8 - - - - 0.0000000000000017 76.0
HKD2_k127_4033865_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 1.404e-278 891.0
HKD2_k127_4033865_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 7.297e-249 786.0
HKD2_k127_4033865_2 Aminotransferase class-III K00833,K03851,K12256,K15372 - 2.6.1.113,2.6.1.55,2.6.1.62,2.6.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 578.0
HKD2_k127_4033865_3 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 503.0
HKD2_k127_4033865_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 388.0
HKD2_k127_4033865_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 379.0
HKD2_k127_4033865_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 362.0
HKD2_k127_4033865_7 Ribosomal RNA adenine dimethylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001011 252.0
HKD2_k127_4033865_8 GGDEF Domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000002972 141.0
HKD2_k127_4044387_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 3.762e-198 642.0
HKD2_k127_4044387_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 421.0
HKD2_k127_4044387_10 Psort location Cytoplasmic, score - - - 0.000952 47.0
HKD2_k127_4044387_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 368.0
HKD2_k127_4044387_3 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001082 285.0
HKD2_k127_4044387_4 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000004127 227.0
HKD2_k127_4044387_5 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020,K19711 - 1.1.1.31,1.1.1.387 0.00000000000000000000000000000000000000000000000000000000004316 216.0
HKD2_k127_4044387_6 2Fe-2S -binding K13483 - - 0.000000000000000000000000000000000000000000000000000000000121 212.0
HKD2_k127_4044387_7 cellulose binding - - - 0.0000000000000000000000000000000000000001102 162.0
HKD2_k127_4044387_9 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000005254 61.0
HKD2_k127_4047972_0 Thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 7.232e-259 809.0
HKD2_k127_4047972_1 FAD dependent oxidoreductase K13796 - - 2.225e-205 649.0
HKD2_k127_4047972_10 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.000000000000002557 76.0
HKD2_k127_4047972_11 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000003551 70.0
HKD2_k127_4047972_2 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 599.0
HKD2_k127_4047972_3 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 509.0
HKD2_k127_4047972_4 TIGRFAM CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 418.0
HKD2_k127_4047972_5 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 376.0
HKD2_k127_4047972_6 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 309.0
HKD2_k127_4047972_7 Universal stress protein UspA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001331 283.0
HKD2_k127_4047972_8 of the drug metabolite transporter (DMT) superfamily - GO:0003333,GO:0003674,GO:0005215,GO:0005302,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015179,GO:0015192,GO:0015196,GO:0015238,GO:0015318,GO:0015711,GO:0015801,GO:0015807,GO:0015823,GO:0015827,GO:0015828,GO:0015849,GO:0015893,GO:0016020,GO:0022857,GO:0034220,GO:0042221,GO:0042493,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000004102 214.0
HKD2_k127_4047972_9 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000002489 200.0
HKD2_k127_4056695_0 protein conserved in bacteria K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 477.0
HKD2_k127_4056695_1 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 441.0
HKD2_k127_4056695_10 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000541 166.0
HKD2_k127_4056695_11 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000108 121.0
HKD2_k127_4056695_12 Tripartite tricarboxylate transporter TctB family - - - 0.00000000008043 72.0
HKD2_k127_4056695_13 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.00003248 55.0
HKD2_k127_4056695_2 Chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 418.0
HKD2_k127_4056695_3 transmembrane transport K02025,K05814,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 342.0
HKD2_k127_4056695_4 PFAM Alcohol dehydrogenase GroES-like K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 346.0
HKD2_k127_4056695_5 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 321.0
HKD2_k127_4056695_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000009131 246.0
HKD2_k127_4056695_7 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000005959 190.0
HKD2_k127_4056695_8 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000001263 194.0
HKD2_k127_4056695_9 OmpA family K03640 - - 0.00000000000000000000000000000000000000009414 159.0
HKD2_k127_4057955_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 580.0
HKD2_k127_4057955_1 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 492.0
HKD2_k127_4057955_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057,K02564 - 3.1.1.31,3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
HKD2_k127_4057955_3 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002363 248.0
HKD2_k127_4057955_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000004137 186.0
HKD2_k127_4063378_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 6.103e-308 955.0
HKD2_k127_4095527_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 632.0
HKD2_k127_4095527_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 364.0
HKD2_k127_4095527_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 308.0
HKD2_k127_4095527_3 Periplasmic binding protein K01999 - - 0.0001024 46.0
HKD2_k127_4103094_0 Ornithine cyclodeaminase/mu-crystallin family K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 419.0
HKD2_k127_4103094_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
HKD2_k127_4103094_2 Tripartite tricarboxylate transporter family receptor - - - 0.0001025 46.0
HKD2_k127_4111772_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.696e-266 829.0
HKD2_k127_4111772_1 Proton-conducting membrane transporter K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 7.744e-198 631.0
HKD2_k127_4111772_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 470.0
HKD2_k127_4111772_3 Belongs to the FPP GGPP synthase family K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 317.0
HKD2_k127_4111772_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001465 254.0
HKD2_k127_4136334_0 glycogen phosphorylase activity K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 363.0
HKD2_k127_4136334_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000001669 246.0
HKD2_k127_4165933_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.303e-305 955.0
HKD2_k127_4165933_1 elongation factor G K02355 - - 3.005e-276 870.0
HKD2_k127_4165933_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000183 274.0
HKD2_k127_4165933_11 domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000004401 240.0
HKD2_k127_4165933_12 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000004966 211.0
HKD2_k127_4165933_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000006665 203.0
HKD2_k127_4165933_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000009918 196.0
HKD2_k127_4165933_15 Ribosomal protein L17 K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001627 179.0
HKD2_k127_4165933_16 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000841 177.0
HKD2_k127_4165933_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000000000338 146.0
HKD2_k127_4165933_18 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000988 135.0
HKD2_k127_4165933_19 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000000001255 131.0
HKD2_k127_4165933_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.637e-217 704.0
HKD2_k127_4165933_20 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000003876 104.0
HKD2_k127_4165933_21 InterPro IPR014922 - - - 0.0000000000000004089 80.0
HKD2_k127_4165933_22 Ribosomal protein L36 K02919 - - 0.000000000000002312 76.0
HKD2_k127_4165933_23 Protein of unknown function (DUF448) K07742 - - 0.00000000004587 73.0
HKD2_k127_4165933_24 - - - - 0.00000005374 61.0
HKD2_k127_4165933_25 Belongs to the 'phage' integrase family - - - 0.0001579 50.0
HKD2_k127_4165933_3 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 533.0
HKD2_k127_4165933_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 520.0
HKD2_k127_4165933_5 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 525.0
HKD2_k127_4165933_6 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 423.0
HKD2_k127_4165933_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 385.0
HKD2_k127_4165933_8 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 330.0
HKD2_k127_4165933_9 Belongs to the ribF family K07011,K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000323 275.0
HKD2_k127_4212972_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 451.0
HKD2_k127_4212972_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 391.0
HKD2_k127_4212972_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000001105 109.0
HKD2_k127_4229729_0 PFAM NAD dependent epimerase dehydratase family K01784,K08679 - 5.1.3.2,5.1.3.6 0.000000000000000000000000000000000000000000000000000000000007496 216.0
HKD2_k127_4229729_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000002649 164.0
HKD2_k127_4237049_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 2.548e-211 683.0
HKD2_k127_4237049_1 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 446.0
HKD2_k127_4237049_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 419.0
HKD2_k127_4237049_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
HKD2_k127_4237049_4 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 319.0
HKD2_k127_4237049_5 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000002182 220.0
HKD2_k127_4237049_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000003267 128.0
HKD2_k127_4248363_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K12137 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 7.182e-223 707.0
HKD2_k127_4248363_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.618e-214 671.0
HKD2_k127_4248363_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000009656 231.0
HKD2_k127_4248363_11 ACT domain - - - 0.00000000000000000000000000000000000000000000000000003226 191.0
HKD2_k127_4248363_12 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000002257 166.0
HKD2_k127_4248363_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000005234 159.0
HKD2_k127_4248363_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000006226 144.0
HKD2_k127_4248363_15 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000008956 130.0
HKD2_k127_4248363_16 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000005024 99.0
HKD2_k127_4248363_17 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000001592 79.0
HKD2_k127_4248363_18 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000001742 80.0
HKD2_k127_4248363_2 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 5.361e-206 653.0
HKD2_k127_4248363_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 605.0
HKD2_k127_4248363_4 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 579.0
HKD2_k127_4248363_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 487.0
HKD2_k127_4248363_6 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 392.0
HKD2_k127_4248363_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 360.0
HKD2_k127_4248363_8 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 322.0
HKD2_k127_4248363_9 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 304.0
HKD2_k127_4285174_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01582,K01585 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008923,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.1.1.18,4.1.1.19 2.476e-199 638.0
HKD2_k127_4285174_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 463.0
HKD2_k127_4285174_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 391.0
HKD2_k127_4285174_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000009823 226.0
HKD2_k127_4302372_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1237.0
HKD2_k127_4302372_1 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1169.0
HKD2_k127_4302372_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 417.0
HKD2_k127_4302372_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 415.0
HKD2_k127_4302372_4 - - - - 0.00000000000000000007797 92.0
HKD2_k127_4302372_5 Protein of unknown function (DUF2283) - - - 0.00000000000000004837 83.0
HKD2_k127_4318854_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 3.867e-312 968.0
HKD2_k127_4318854_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 419.0
HKD2_k127_4318854_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000002046 226.0
HKD2_k127_4318854_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000006726 198.0
HKD2_k127_4319247_0 MacB-like periplasmic core domain K02004 - - 4.987e-200 652.0
HKD2_k127_4319247_1 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 606.0
HKD2_k127_4319247_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 416.0
HKD2_k127_4319247_3 ABC transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001038 259.0
HKD2_k127_4338623_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 2.149e-214 670.0
HKD2_k127_4338623_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 601.0
HKD2_k127_4338623_10 Permease YjgP YjgQ family protein K07091,K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004763 274.0
HKD2_k127_4338623_11 transferase activity, transferring glycosyl groups K02844 - - 0.00000000000000000000000000000000000000000000000000000000002114 220.0
HKD2_k127_4338623_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 576.0
HKD2_k127_4338623_3 PFAM Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 508.0
HKD2_k127_4338623_4 Metallo-beta-lactamase superfamily K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 510.0
HKD2_k127_4338623_5 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 408.0
HKD2_k127_4338623_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 353.0
HKD2_k127_4338623_7 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 322.0
HKD2_k127_4338623_8 COG0410 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001941 286.0
HKD2_k127_4338623_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009199 285.0
HKD2_k127_4404239_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 507.0
HKD2_k127_4404239_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 491.0
HKD2_k127_4404239_2 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000006347 222.0
HKD2_k127_4404239_3 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000006945 70.0
HKD2_k127_4420157_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874,K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 7.869e-249 787.0
HKD2_k127_4420157_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 4.682e-245 765.0
HKD2_k127_4420157_10 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.000000000000000000000000000000000000000000000000000000001915 205.0
HKD2_k127_4420157_11 Probable zinc-ribbon domain K03704 - - 0.000000000000000000000000000000000003192 139.0
HKD2_k127_4420157_13 CoA carboxylase activity K01965 - 6.4.1.3 0.0000000000000000000000000004451 120.0
HKD2_k127_4420157_14 - - - - 0.00000000000000000000004512 114.0
HKD2_k127_4420157_15 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.0000000000000000000004437 100.0
HKD2_k127_4420157_16 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000007699 56.0
HKD2_k127_4420157_2 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 536.0
HKD2_k127_4420157_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
HKD2_k127_4420157_4 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 388.0
HKD2_k127_4420157_5 peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 364.0
HKD2_k127_4420157_6 Transporter anaerobic C4-dicarboxylate uptake C K03326 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 351.0
HKD2_k127_4420157_7 PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005497 237.0
HKD2_k127_4420157_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
HKD2_k127_4420157_9 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000003573 214.0
HKD2_k127_4428648_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000004833 134.0
HKD2_k127_4428648_1 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000006763 116.0
HKD2_k127_4428648_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000001529 89.0
HKD2_k127_4428648_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000149 83.0
HKD2_k127_4428648_4 DGC domain - - - 0.0000004215 55.0
HKD2_k127_444763_0 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 569.0
HKD2_k127_444763_1 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 563.0
HKD2_k127_444763_2 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 416.0
HKD2_k127_444763_3 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
HKD2_k127_444763_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000003214 231.0
HKD2_k127_444763_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000003609 237.0
HKD2_k127_4457690_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 476.0
HKD2_k127_4457690_1 aldehyde ferredoxin oxidoreductase activity K03738,K11389 - 1.2.7.5,1.2.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 320.0
HKD2_k127_4458461_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 555.0
HKD2_k127_4458461_1 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 472.0
HKD2_k127_4458461_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 313.0
HKD2_k127_4458461_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000005123 259.0
HKD2_k127_4458461_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000001768 161.0
HKD2_k127_4458461_5 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000003824 94.0
HKD2_k127_4462724_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 4.571e-222 706.0
HKD2_k127_4462724_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 494.0
HKD2_k127_4462724_10 PFAM Peptidase family M28 - - - 0.0000000000000000000000000000000000001559 158.0
HKD2_k127_4462724_11 Domain of unknown function (DUF4203) - - - 0.00000000000000000008105 95.0
HKD2_k127_4462724_12 diguanylate cyclase - - - 0.00000000000000001039 94.0
HKD2_k127_4462724_2 Phosphoadenosine phosphosulfate reductase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 422.0
HKD2_k127_4462724_3 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 359.0
HKD2_k127_4462724_4 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 358.0
HKD2_k127_4462724_5 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 297.0
HKD2_k127_4462724_6 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000342 289.0
HKD2_k127_4462724_7 CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000007533 239.0
HKD2_k127_4462724_8 Function Code 14.4 Transport and Binding Proteins Carbohydrates, organic alcohols, and acids K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000001374 236.0
HKD2_k127_4462724_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000001078 216.0
HKD2_k127_4536396_0 Aldo/keto reductase family K19265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 505.0
HKD2_k127_4536396_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 342.0
HKD2_k127_4536396_2 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000001227 137.0
HKD2_k127_4536396_3 - K04517 - 1.3.1.12 0.00000000000000000000000000002788 121.0
HKD2_k127_4547595_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 7.525e-240 751.0
HKD2_k127_4547595_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 580.0
HKD2_k127_4547595_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, His Kinase A (phosphoacceptor) domain, Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 462.0
HKD2_k127_4547595_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 435.0
HKD2_k127_4547595_4 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 392.0
HKD2_k127_4547595_5 response regulator K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000193 275.0
HKD2_k127_4547595_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000006949 237.0
HKD2_k127_4547595_7 PFAM Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000007445 57.0
HKD2_k127_4547595_8 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.00000288 49.0
HKD2_k127_4548123_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 574.0
HKD2_k127_4548123_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 517.0
HKD2_k127_4548123_10 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 256.0
HKD2_k127_4548123_11 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000006559 244.0
HKD2_k127_4548123_12 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001368 218.0
HKD2_k127_4548123_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000006365 198.0
HKD2_k127_4548123_14 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000409 193.0
HKD2_k127_4548123_15 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000008965 190.0
HKD2_k127_4548123_16 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000001766 179.0
HKD2_k127_4548123_17 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000003359 149.0
HKD2_k127_4548123_18 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000003612 149.0
HKD2_k127_4548123_19 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000003305 139.0
HKD2_k127_4548123_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 470.0
HKD2_k127_4548123_20 CBS domain - - - 0.00000000000000000000000000000005625 133.0
HKD2_k127_4548123_21 Smr domain - - - 0.0000000000000000000000000000818 122.0
HKD2_k127_4548123_22 Evidence 5 No homology to any previously reported sequences K08303 - - 0.000000000000000000000002587 106.0
HKD2_k127_4548123_23 Putative regulatory protein - - - 0.0000000004272 63.0
HKD2_k127_4548123_24 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.00000001656 56.0
HKD2_k127_4548123_25 PFAM peptidase M48 Ste24p - - - 0.00001992 49.0
HKD2_k127_4548123_3 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 446.0
HKD2_k127_4548123_4 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 422.0
HKD2_k127_4548123_5 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
HKD2_k127_4548123_6 Zn-dependent hydrolase, glyoxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 354.0
HKD2_k127_4548123_7 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 341.0
HKD2_k127_4548123_8 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 307.0
HKD2_k127_4548123_9 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 290.0
HKD2_k127_4594418_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 4.551e-247 767.0
HKD2_k127_4594418_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 496.0
HKD2_k127_4594418_10 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.000000000000000000000000003845 112.0
HKD2_k127_4594418_11 Domain of unknown function (DUF4382) - - - 0.000003379 60.0
HKD2_k127_4594418_12 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000323 55.0
HKD2_k127_4594418_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 344.0
HKD2_k127_4594418_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 280.0
HKD2_k127_4594418_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000003078 230.0
HKD2_k127_4594418_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K07566 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.87 0.000000000000000000000000000000000000000000000002622 180.0
HKD2_k127_4594418_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000002457 177.0
HKD2_k127_4594418_7 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0006970,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009268,GO:0009409,GO:0009628,GO:0009651,GO:0009987,GO:0010467,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043021,GO:0043023,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000008283 134.0
HKD2_k127_4594418_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000003225 142.0
HKD2_k127_4594418_9 - - - - 0.0000000000000000000000000001383 121.0
HKD2_k127_4639061_0 SAF K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 528.0
HKD2_k127_4639061_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 423.0
HKD2_k127_4639061_2 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 391.0
HKD2_k127_4647177_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 610.0
HKD2_k127_4647177_1 Belongs to the D-glutamate cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 382.0
HKD2_k127_4647177_10 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000001239 139.0
HKD2_k127_4647177_11 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000007879 72.0
HKD2_k127_4647177_12 ThiS family K03636 - - 0.00006939 52.0
HKD2_k127_4647177_2 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 374.0
HKD2_k127_4647177_3 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 373.0
HKD2_k127_4647177_4 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 353.0
HKD2_k127_4647177_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 325.0
HKD2_k127_4647177_6 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 328.0
HKD2_k127_4647177_7 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 294.0
HKD2_k127_4647177_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000003423 198.0
HKD2_k127_4647177_9 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000001028 187.0
HKD2_k127_4683371_0 PFAM aminotransferase class-III K01845,K21585 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016769,GO:0016999,GO:0017144,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0046440,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.111,5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 449.0
HKD2_k127_4683371_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000005823 198.0
HKD2_k127_4690840_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4e-323 1001.0
HKD2_k127_4690840_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 379.0
HKD2_k127_4690840_2 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 334.0
HKD2_k127_4690840_3 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000001212 199.0
HKD2_k127_4690840_4 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000003251 159.0
HKD2_k127_471258_0 drug resistance transporter, EmrB QacA subfamily K03446 - - 4.877e-197 627.0
HKD2_k127_471258_1 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 501.0
HKD2_k127_471258_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 435.0
HKD2_k127_471258_3 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 344.0
HKD2_k127_471258_4 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000356 265.0
HKD2_k127_471258_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000008121 230.0
HKD2_k127_471258_6 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000006925 168.0
HKD2_k127_471258_7 Protein of unknown function (DUF992) - - - 0.000000000000000000000000002571 120.0
HKD2_k127_4726919_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 1.22e-233 753.0
HKD2_k127_4726919_1 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 464.0
HKD2_k127_4726919_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 307.0
HKD2_k127_4726919_3 PFAM transport-associated - - - 0.00000000000000000000000000000000000000000000000000000000003835 220.0
HKD2_k127_4726919_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000005678 218.0
HKD2_k127_4726919_5 Competence-damaged protein - - - 0.000000000000000000000000000000000000000000000000000001406 196.0
HKD2_k127_4726919_6 protein homooligomerization - - - 0.00000000000000000007665 100.0
HKD2_k127_4726919_7 Cupin domain - - - 0.0000000000003606 74.0
HKD2_k127_4796520_0 Major facilitator Superfamily K03446,K07786 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 1.986e-245 776.0
HKD2_k127_4796520_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 1.89e-196 628.0
HKD2_k127_4796520_2 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 520.0
HKD2_k127_4796520_3 Cupin - - - 0.0000000000000000000000000000000000000000000000000006307 186.0
HKD2_k127_484900_0 Trap dicarboxylate transporter, dctm subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 305.0
HKD2_k127_484900_1 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000001531 214.0
HKD2_k127_484900_2 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000005272 201.0
HKD2_k127_484900_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000597 121.0
HKD2_k127_484900_4 DNA topological change - - - 0.0000000000000000000344 92.0
HKD2_k127_484900_5 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000005238 58.0
HKD2_k127_4949252_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 536.0
HKD2_k127_4949252_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 448.0
HKD2_k127_4949252_10 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009242 260.0
HKD2_k127_4949252_11 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000002581 245.0
HKD2_k127_4949252_12 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008711 239.0
HKD2_k127_4949252_13 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000001659 236.0
HKD2_k127_4949252_14 Cytochrome c - - - 0.0000000000000000002224 93.0
HKD2_k127_4949252_16 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.000801 49.0
HKD2_k127_4949252_2 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 371.0
HKD2_k127_4949252_3 transport system permease K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 352.0
HKD2_k127_4949252_4 Major facilitator Superfamily K08168 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 348.0
HKD2_k127_4949252_5 1-aminocyclopropane-1-carboxylate deaminase K01505,K05396 - 3.5.99.7,4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 327.0
HKD2_k127_4949252_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 324.0
HKD2_k127_4949252_7 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 304.0
HKD2_k127_4949252_8 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 295.0
HKD2_k127_4949252_9 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003132 262.0
HKD2_k127_4949313_0 Insertion element 4 transposase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000001658 254.0
HKD2_k127_4949313_1 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004681 229.0
HKD2_k127_4949313_2 DNA catabolic process, exonucleolytic K07464 - 3.1.12.1 0.000000000006881 74.0
HKD2_k127_5102377_0 COG5659 FOG Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 405.0
HKD2_k127_5102377_1 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 403.0
HKD2_k127_5110441_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 605.0
HKD2_k127_5110441_1 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 423.0
HKD2_k127_5110441_10 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000001162 219.0
HKD2_k127_5110441_11 Putative FMN-binding domain K07734 - - 0.000000000000000000000000000000000000000000000000005709 188.0
HKD2_k127_5110441_12 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000004854 157.0
HKD2_k127_5110441_13 alcohol dehydrogenase - - - 0.0000000000000000000000000000000003914 144.0
HKD2_k127_5110441_14 methylamine metabolic process K15977 - - 0.0000000000000000000000000000003015 136.0
HKD2_k127_5110441_15 PFAM Transposase IS66 family K07484 - - 0.00000000000001223 76.0
HKD2_k127_5110441_16 PFAM Helix-turn-helix - - - 0.0000000000371 69.0
HKD2_k127_5110441_17 Family 4 glycosyl hydrolase C-terminal domain K07406 - 3.2.1.22 0.00000002638 60.0
HKD2_k127_5110441_18 - - - - 0.00000002687 58.0
HKD2_k127_5110441_19 iron dependent repressor - - - 0.00003641 51.0
HKD2_k127_5110441_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 416.0
HKD2_k127_5110441_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 369.0
HKD2_k127_5110441_5 Binding-protein-dependent transport system inner membrane component K02026,K17236 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 327.0
HKD2_k127_5110441_6 protein, Hemolysin III K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 289.0
HKD2_k127_5110441_7 Binding-protein-dependent transport system inner membrane component K17242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003688 285.0
HKD2_k127_5110441_8 carbohydrate transport K17241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006852 274.0
HKD2_k127_5110441_9 Penicillin-insensitive murein endopeptidase K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000000001085 247.0
HKD2_k127_5111487_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 336.0
HKD2_k127_5111487_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 327.0
HKD2_k127_5111487_10 Putative regulatory protein - - - 0.00000000000000000000000000001554 119.0
HKD2_k127_5111487_11 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000004956 97.0
HKD2_k127_5111487_12 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000001225 95.0
HKD2_k127_5111487_13 Tripartite tricarboxylate transporter TctB family - - - 0.0002029 53.0
HKD2_k127_5111487_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 325.0
HKD2_k127_5111487_3 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002834 274.0
HKD2_k127_5111487_4 Domain of unknown function (DUF1732) - GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007006 261.0
HKD2_k127_5111487_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000004292 254.0
HKD2_k127_5111487_6 Essential for recycling GMP and indirectly, cGMP K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000008523 246.0
HKD2_k127_5111487_7 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.000000000000000000000000000000000000000000000000000000009127 213.0
HKD2_k127_5111487_8 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000001516 164.0
HKD2_k127_5111487_9 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000004053 159.0
HKD2_k127_5128643_0 Predicted Permease Membrane Region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 427.0
HKD2_k127_5128643_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 374.0
HKD2_k127_5128643_2 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003234 263.0
HKD2_k127_5128643_3 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000003978 231.0
HKD2_k127_5128643_4 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000001014 189.0
HKD2_k127_5128643_5 - - - - 0.000000000000000000000000000000000004329 144.0
HKD2_k127_5138585_0 Pyridoxal-phosphate dependent enzyme - - - 5.646e-223 700.0
HKD2_k127_5138585_1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 591.0
HKD2_k127_5138585_2 threonine synthase activity K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 450.0
HKD2_k127_5138585_3 DoxX K15977 - - 0.00000000000000000000000000000004382 129.0
HKD2_k127_5138585_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000001137 128.0
HKD2_k127_5138585_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000004153 120.0
HKD2_k127_5138585_6 DinB superfamily - - - 0.00000000000000000004633 101.0
HKD2_k127_5138585_7 DinB superfamily - - - 0.00000000000000000125 97.0
HKD2_k127_5144646_0 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000002337 240.0
HKD2_k127_5144646_1 PFAM Cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000008055 173.0
HKD2_k127_5144646_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000001591 143.0
HKD2_k127_5144646_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000005808 130.0
HKD2_k127_5152734_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 4.525e-311 984.0
HKD2_k127_5152734_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 5.859e-244 760.0
HKD2_k127_5152734_10 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 317.0
HKD2_k127_5152734_11 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 331.0
HKD2_k127_5152734_12 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 314.0
HKD2_k127_5152734_13 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 312.0
HKD2_k127_5152734_14 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 296.0
HKD2_k127_5152734_15 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001031 295.0
HKD2_k127_5152734_16 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 283.0
HKD2_k127_5152734_17 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006708 276.0
HKD2_k127_5152734_18 pfam abc K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007111 265.0
HKD2_k127_5152734_19 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004616 252.0
HKD2_k127_5152734_2 Protein tyrosine kinase - - - 4.093e-205 664.0
HKD2_k127_5152734_20 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000102 259.0
HKD2_k127_5152734_21 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000003034 242.0
HKD2_k127_5152734_22 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000004289 244.0
HKD2_k127_5152734_23 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001068 220.0
HKD2_k127_5152734_24 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000007226 214.0
HKD2_k127_5152734_25 Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000002737 201.0
HKD2_k127_5152734_26 transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000334 182.0
HKD2_k127_5152734_28 Domain of unknown function (DUF4392) K22210 - 4.2.1.48 0.0000000000000000000000000000000000000008467 161.0
HKD2_k127_5152734_29 Response regulator receiver domain - - - 0.0000000000000000000000000000005599 127.0
HKD2_k127_5152734_3 PFAM Type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 519.0
HKD2_k127_5152734_30 4Fe-4S dicluster domain K03522,K05337 - - 0.000000000000000000000000001917 119.0
HKD2_k127_5152734_31 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000007001 122.0
HKD2_k127_5152734_32 Protein of unknown function (DUF1232) - - - 0.000000000000000000000004391 109.0
HKD2_k127_5152734_33 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000007699 106.0
HKD2_k127_5152734_34 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000008303 93.0
HKD2_k127_5152734_35 cobalt ion transport K02009 - - 0.0000000000000000009234 97.0
HKD2_k127_5152734_37 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000003601 87.0
HKD2_k127_5152734_39 Pfam SEC-C motif - - - 0.0000000000009515 80.0
HKD2_k127_5152734_4 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 519.0
HKD2_k127_5152734_40 PFAM nitrogen-fixing NifU - - - 0.000000002875 59.0
HKD2_k127_5152734_5 Allophanate hydrolase subunit 2 K06350 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 467.0
HKD2_k127_5152734_6 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 425.0
HKD2_k127_5152734_7 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 397.0
HKD2_k127_5152734_8 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 327.0
HKD2_k127_5152734_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 326.0
HKD2_k127_5153492_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1104.0
HKD2_k127_5153492_1 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 508.0
HKD2_k127_5153492_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 419.0
HKD2_k127_5153492_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 397.0
HKD2_k127_5153492_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 377.0
HKD2_k127_5153492_5 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 383.0
HKD2_k127_5153492_6 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 354.0
HKD2_k127_5153492_7 PFAM monooxygenase FAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000001181 223.0
HKD2_k127_5153492_8 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.0000008978 54.0
HKD2_k127_5153492_9 Beta-lactamase superfamily domain - - - 0.000958 45.0
HKD2_k127_5179010_0 SAM-dependent RNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000001403 194.0
HKD2_k127_5179010_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000009549 176.0
HKD2_k127_5179010_2 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000001039 68.0
HKD2_k127_5183352_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.0 1110.0
HKD2_k127_5183352_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 7.214e-204 644.0
HKD2_k127_5183352_10 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
HKD2_k127_5183352_11 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000008801 244.0
HKD2_k127_5183352_12 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000007667 204.0
HKD2_k127_5183352_13 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000001739 173.0
HKD2_k127_5183352_14 Lysin motif - - - 0.000000000000000000000000000008252 136.0
HKD2_k127_5183352_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000001643 85.0
HKD2_k127_5183352_2 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 557.0
HKD2_k127_5183352_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 528.0
HKD2_k127_5183352_4 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 482.0
HKD2_k127_5183352_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 420.0
HKD2_k127_5183352_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 393.0
HKD2_k127_5183352_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 341.0
HKD2_k127_5183352_8 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 338.0
HKD2_k127_5183352_9 DNA recombination-mediator protein A K01972,K02342,K04096 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 2.7.7.7,6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 316.0
HKD2_k127_5193312_0 AMP-dependent synthetase and ligase K01895,K08295 - 6.2.1.1,6.2.1.32 8.463e-253 790.0
HKD2_k127_5193312_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 398.0
HKD2_k127_5193312_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000001603 76.0
HKD2_k127_5213528_0 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 384.0
HKD2_k127_5213528_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 380.0
HKD2_k127_5213528_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 319.0
HKD2_k127_5213528_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 315.0
HKD2_k127_5213528_4 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
HKD2_k127_5213528_5 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000005009 213.0
HKD2_k127_5213528_6 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000003256 206.0
HKD2_k127_5213528_7 major facilitator superfamily - - - 0.00000000000000000000000000000000009467 141.0
HKD2_k127_5213528_8 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000003094 117.0
HKD2_k127_5213528_9 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K21417 - - 0.00000000000000000000008991 99.0
HKD2_k127_5217031_0 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000001962 164.0
HKD2_k127_5217031_1 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000002574 116.0
HKD2_k127_5217031_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000004197 75.0
HKD2_k127_5217031_3 Putative zinc-finger - - - 0.0001722 53.0
HKD2_k127_5226472_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 526.0
HKD2_k127_5226472_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 287.0
HKD2_k127_5226472_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000643 240.0
HKD2_k127_5226472_3 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001082 260.0
HKD2_k127_5226472_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000002108 198.0
HKD2_k127_5226472_5 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000004829 169.0
HKD2_k127_5226472_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000002499 118.0
HKD2_k127_5226472_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0001515 55.0
HKD2_k127_5278848_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00928,K12524 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 622.0
HKD2_k127_5278848_1 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 539.0
HKD2_k127_5278848_10 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 340.0
HKD2_k127_5278848_11 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 319.0
HKD2_k127_5278848_12 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006764 284.0
HKD2_k127_5278848_13 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001257 251.0
HKD2_k127_5278848_14 RNA pseudouridylate synthase K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000002415 244.0
HKD2_k127_5278848_15 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000001534 242.0
HKD2_k127_5278848_16 Prephenate dehydrogenase K00210,K00220,K00800,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43,2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000002265 236.0
HKD2_k127_5278848_17 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000002672 221.0
HKD2_k127_5278848_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000001224 214.0
HKD2_k127_5278848_19 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000001486 209.0
HKD2_k127_5278848_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 444.0
HKD2_k127_5278848_20 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001687 207.0
HKD2_k127_5278848_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000002236 198.0
HKD2_k127_5278848_22 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K01007,K03977,K08591,K22278 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15,2.7.9.2,3.5.1.104 0.0000000000000000000000000000000000000000000000000002984 191.0
HKD2_k127_5278848_23 HEPN domain - - - 0.00000000000000000000000000000000000000000000000002533 183.0
HKD2_k127_5278848_24 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000001309 177.0
HKD2_k127_5278848_25 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000003794 173.0
HKD2_k127_5278848_26 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000006421 167.0
HKD2_k127_5278848_27 lipopolysaccharide binding K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.000000000000000000000000000000000000004305 152.0
HKD2_k127_5278848_28 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000001415 136.0
HKD2_k127_5278848_29 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000008001 111.0
HKD2_k127_5278848_3 Prephenate dehydratase K00661,K01713,K04092,K04093,K04516,K04518,K14170,K14187 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,2.3.1.79,4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 438.0
HKD2_k127_5278848_30 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01236 - 3.2.1.141 0.000000000000000000000004565 108.0
HKD2_k127_5278848_31 Phosphotransferase System K11189 - - 0.0000000000000000000001334 100.0
HKD2_k127_5278848_32 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000001018 78.0
HKD2_k127_5278848_33 transcriptional - - - 0.000000000007541 71.0
HKD2_k127_5278848_34 NADPH-dependent FMN reductase - - - 0.000000000009608 75.0
HKD2_k127_5278848_35 Lipopolysaccharide-assembly, LptC-related - - - 0.0000003273 61.0
HKD2_k127_5278848_36 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000005003 58.0
HKD2_k127_5278848_4 Response regulator receiver K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 432.0
HKD2_k127_5278848_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 402.0
HKD2_k127_5278848_6 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 359.0
HKD2_k127_5278848_7 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 360.0
HKD2_k127_5278848_8 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 361.0
HKD2_k127_5278848_9 P-loop ATPase protein family K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 346.0
HKD2_k127_5281769_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.055e-258 805.0
HKD2_k127_5281769_1 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 3.954e-241 758.0
HKD2_k127_5281769_2 carboxylase, biotin carboxylase K01961,K01965,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 462.0
HKD2_k127_5281769_3 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 403.0
HKD2_k127_5281769_4 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
HKD2_k127_5281769_5 Evidence 5 No homology to any previously reported sequences K03765 - - 0.0000000000000000000000000000000000000000000000000000000000000000004554 253.0
HKD2_k127_5281769_6 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000003084 222.0
HKD2_k127_5281769_7 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000001771 180.0
HKD2_k127_5281769_8 Biotin-lipoyl like K01960,K01965,K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.1,6.4.1.3,6.4.1.4 0.0000000000000000000000000000007321 128.0
HKD2_k127_529039_0 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 1.239e-229 725.0
HKD2_k127_529039_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 548.0
HKD2_k127_529039_10 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 332.0
HKD2_k127_529039_11 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 326.0
HKD2_k127_529039_12 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
HKD2_k127_529039_13 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000000000000000000000000000005352 262.0
HKD2_k127_529039_14 amino acid aldolase or racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008874 254.0
HKD2_k127_529039_15 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000001885 209.0
HKD2_k127_529039_16 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000002568 206.0
HKD2_k127_529039_17 CHAD domain containing protein - - - 0.00000000000000000000000000000000000002155 163.0
HKD2_k127_529039_18 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000001236 149.0
HKD2_k127_529039_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 483.0
HKD2_k127_529039_3 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 451.0
HKD2_k127_529039_4 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 455.0
HKD2_k127_529039_5 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 421.0
HKD2_k127_529039_6 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 377.0
HKD2_k127_529039_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 356.0
HKD2_k127_529039_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 356.0
HKD2_k127_529039_9 PFAM Iron-containing alcohol dehydrogenase K13954,K19954 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 348.0
HKD2_k127_5324548_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 302.0
HKD2_k127_5324548_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000003873 157.0
HKD2_k127_5348655_0 ABC transporter transmembrane region K06147,K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 468.0
HKD2_k127_5348655_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 440.0
HKD2_k127_5348655_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 383.0
HKD2_k127_5348655_3 cellular manganese ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 362.0
HKD2_k127_5348655_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 355.0
HKD2_k127_5348655_5 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000001435 181.0
HKD2_k127_5348655_6 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000001978 149.0
HKD2_k127_5357207_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.216e-318 982.0
HKD2_k127_5357207_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 1.483e-197 625.0
HKD2_k127_5357207_10 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000002459 178.0
HKD2_k127_5357207_11 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000006701 184.0
HKD2_k127_5357207_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000003911 152.0
HKD2_k127_5357207_13 PFAM transport-associated - - - 0.00000000000000000000000000000002301 143.0
HKD2_k127_5357207_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997,K01207 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 0.00000000000000000000000001117 116.0
HKD2_k127_5357207_15 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000001582 115.0
HKD2_k127_5357207_16 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000002618 94.0
HKD2_k127_5357207_17 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000004749 97.0
HKD2_k127_5357207_18 Trm112p-like protein K09791 - - 0.000000000000000006561 85.0
HKD2_k127_5357207_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 540.0
HKD2_k127_5357207_3 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 536.0
HKD2_k127_5357207_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 461.0
HKD2_k127_5357207_5 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 388.0
HKD2_k127_5357207_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
HKD2_k127_5357207_7 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000001343 270.0
HKD2_k127_5357207_8 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000004281 234.0
HKD2_k127_5357207_9 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000001599 199.0
HKD2_k127_5416622_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000004364 184.0
HKD2_k127_5416622_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000002198 104.0
HKD2_k127_5445273_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 374.0
HKD2_k127_5445273_1 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000007076 168.0
HKD2_k127_5450830_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 447.0
HKD2_k127_5450830_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 434.0
HKD2_k127_5450830_10 MMPL family K07003 - - 0.000000000000000000000000000000000008875 147.0
HKD2_k127_5450830_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000001438 120.0
HKD2_k127_5450830_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000006028 89.0
HKD2_k127_5450830_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.000000000000003359 87.0
HKD2_k127_5450830_14 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.0000000003266 72.0
HKD2_k127_5450830_2 radical SAM domain protein K07011,K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 417.0
HKD2_k127_5450830_3 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 396.0
HKD2_k127_5450830_4 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 387.0
HKD2_k127_5450830_5 3-oxoacyl-[acyl-carrier-protein] synthase activity K05551,K09458,K14667 - 2.3.1.179,2.3.1.235,2.3.1.260 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 351.0
HKD2_k127_5450830_6 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001185 278.0
HKD2_k127_5450830_8 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
HKD2_k127_5492500_0 Elongation factor SelB, winged helix K03833 - - 3.427e-248 781.0
HKD2_k127_5492500_1 TRAP transporter, 4TM 12TM fusion protein - - - 3.788e-203 650.0
HKD2_k127_5492500_10 E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 344.0
HKD2_k127_5492500_11 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 308.0
HKD2_k127_5492500_12 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 305.0
HKD2_k127_5492500_13 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000002488 205.0
HKD2_k127_5492500_14 mRNA catabolic process K06950,K09163 - - 0.00000000000000000000000000000000000000000000000002209 185.0
HKD2_k127_5492500_16 PFAM Tripartite ATP-independent periplasmic K11689 - - 0.00000000000000000000001749 106.0
HKD2_k127_5492500_17 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000468 97.0
HKD2_k127_5492500_18 protein secretion K03116 - - 0.000000000000000002428 85.0
HKD2_k127_5492500_19 PilZ domain K02676 - - 0.000000000005337 72.0
HKD2_k127_5492500_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 443.0
HKD2_k127_5492500_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 406.0
HKD2_k127_5492500_4 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 410.0
HKD2_k127_5492500_5 Transketolase, central region K11381,K21417 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 396.0
HKD2_k127_5492500_6 TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 389.0
HKD2_k127_5492500_7 E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 373.0
HKD2_k127_5492500_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 364.0
HKD2_k127_5492500_9 PFAM Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 355.0
HKD2_k127_5515067_0 Glycogen debranching enzyme - - - 0.0 1017.0
HKD2_k127_5515067_1 Elongator protein 3, MiaB family, Radical SAM K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 546.0
HKD2_k127_5515067_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 511.0
HKD2_k127_5515067_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 454.0
HKD2_k127_5515067_4 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.0000000001987 65.0
HKD2_k127_5515067_6 cytotoxic translational repressor of toxin-antitoxin K06218 - - 0.000002145 53.0
HKD2_k127_5547677_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 468.0
HKD2_k127_5547677_1 cellulose binding - - - 0.00000000000000000000000000000000000000000007748 176.0
HKD2_k127_5547677_2 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.00000000000000001319 96.0
HKD2_k127_5547677_3 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000001175 77.0
HKD2_k127_5552856_0 transmembrane transporter activity - - - 0.0 1667.0
HKD2_k127_5552856_1 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.0 1240.0
HKD2_k127_5552856_10 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001316 276.0
HKD2_k127_5552856_11 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001677 267.0
HKD2_k127_5552856_12 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000557 233.0
HKD2_k127_5552856_13 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001803 239.0
HKD2_k127_5552856_14 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000005269 216.0
HKD2_k127_5552856_15 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000003909 183.0
HKD2_k127_5552856_16 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000002639 186.0
HKD2_k127_5552856_17 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000006438 154.0
HKD2_k127_5552856_18 mRNA binding - - - 0.00000000000000000000000000001788 119.0
HKD2_k127_5552856_19 Uncharacterized protein family UPF0054 K07042 - - 0.0000000000000000000000000001822 121.0
HKD2_k127_5552856_2 Glycyl-tRNA synthetase beta subunit K01879,K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 1.433e-250 793.0
HKD2_k127_5552856_20 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000001144 112.0
HKD2_k127_5552856_21 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000614 112.0
HKD2_k127_5552856_22 Tetratricopeptide repeat - - - 0.00000000000000000000002565 107.0
HKD2_k127_5552856_23 signal transduction histidine kinase - - - 0.000000000000000002491 90.0
HKD2_k127_5552856_24 WHG domain - - - 0.00000006802 61.0
HKD2_k127_5552856_3 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 582.0
HKD2_k127_5552856_4 Glycyl-tRNA synthetase, alpha subunit K01878,K14164 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016875,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 501.0
HKD2_k127_5552856_5 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 477.0
HKD2_k127_5552856_6 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 436.0
HKD2_k127_5552856_7 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 386.0
HKD2_k127_5552856_8 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 362.0
HKD2_k127_5552856_9 KH domain K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 288.0
HKD2_k127_5558604_0 transmembrane transporter activity K03296 - - 0.0 1041.0
HKD2_k127_5558604_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000004012 256.0
HKD2_k127_5558604_2 smart pdz dhr glgf K04771,K08372 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000002065 201.0
HKD2_k127_5558604_3 PFAM Outer membrane efflux protein - - - 0.0000000000002715 82.0
HKD2_k127_5563106_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 9.945e-219 684.0
HKD2_k127_5563106_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 399.0
HKD2_k127_5563106_2 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002436 274.0
HKD2_k127_5563106_3 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000001778 159.0
HKD2_k127_5563106_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000601 43.0
HKD2_k127_5591506_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 509.0
HKD2_k127_5591506_1 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 478.0
HKD2_k127_5591506_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 458.0
HKD2_k127_5591506_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 444.0
HKD2_k127_5591506_4 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004616 295.0
HKD2_k127_5591506_5 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000000000137 127.0
HKD2_k127_5591506_6 - - - - 0.000000000001072 76.0
HKD2_k127_5591506_7 - - - - 0.00000000009225 67.0
HKD2_k127_5591506_8 - - - - 0.00000002552 64.0
HKD2_k127_5681444_0 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004239 250.0
HKD2_k127_5681444_1 HicB family K18843 - - 0.000000000000000000000000000000000000004061 149.0
HKD2_k127_5681444_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000534 110.0
HKD2_k127_5681444_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000008103 91.0
HKD2_k127_5681444_4 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000004311 96.0
HKD2_k127_5681444_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0003764 51.0
HKD2_k127_5681444_6 SMART Chromosomal replication initiator DnaA domain - - - 0.0003764 51.0
HKD2_k127_5681444_7 SMART Chromosomal replication initiator DnaA domain - - - 0.0005876 47.0
HKD2_k127_5683158_0 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 433.0
HKD2_k127_5683158_1 carbohydrate transport K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008843 272.0
HKD2_k127_5683158_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000000000000000005883 190.0
HKD2_k127_5683158_3 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000008088 166.0
HKD2_k127_5683158_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000001458 124.0
HKD2_k127_5683158_5 thiamine-phosphate kinase activity K00946 - 2.7.4.16 0.00000000000000003527 85.0
HKD2_k127_5683158_6 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.0000002842 63.0
HKD2_k127_5686078_0 4Fe-4S dicluster domain K00184 - - 0.0 1218.0
HKD2_k127_5686078_1 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.0 1174.0
HKD2_k127_5686078_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 496.0
HKD2_k127_5686078_11 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 499.0
HKD2_k127_5686078_12 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 406.0
HKD2_k127_5686078_13 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 403.0
HKD2_k127_5686078_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 390.0
HKD2_k127_5686078_15 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 385.0
HKD2_k127_5686078_16 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 394.0
HKD2_k127_5686078_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005362 369.0
HKD2_k127_5686078_18 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 306.0
HKD2_k127_5686078_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 306.0
HKD2_k127_5686078_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.248e-303 939.0
HKD2_k127_5686078_20 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
HKD2_k127_5686078_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000006332 239.0
HKD2_k127_5686078_22 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
HKD2_k127_5686078_23 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000002697 224.0
HKD2_k127_5686078_24 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000002938 236.0
HKD2_k127_5686078_25 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000007763 216.0
HKD2_k127_5686078_26 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000001706 196.0
HKD2_k127_5686078_27 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000002477 171.0
HKD2_k127_5686078_28 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000007743 173.0
HKD2_k127_5686078_29 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000002185 166.0
HKD2_k127_5686078_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.659e-277 863.0
HKD2_k127_5686078_30 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000003608 149.0
HKD2_k127_5686078_31 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000000005315 96.0
HKD2_k127_5686078_32 - - - - 0.000000000000000002628 90.0
HKD2_k127_5686078_4 ATPase (P-type) K01535 - 3.6.3.6 1.117e-250 801.0
HKD2_k127_5686078_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.254e-211 664.0
HKD2_k127_5686078_6 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 4.489e-207 651.0
HKD2_k127_5686078_7 Polysulphide reductase, NrfD K00185 - - 6.692e-194 615.0
HKD2_k127_5686078_8 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 595.0
HKD2_k127_5686078_9 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 585.0
HKD2_k127_5734324_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 609.0
HKD2_k127_5734324_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 450.0
HKD2_k127_5734324_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 436.0
HKD2_k127_5738666_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 530.0
HKD2_k127_5738666_1 Belongs to the 3-oxoacid CoA-transferase family K01026 - 2.8.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 466.0
HKD2_k127_5738666_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 416.0
HKD2_k127_5738666_3 proline dipeptidase activity K18829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 413.0
HKD2_k127_5738666_4 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 343.0
HKD2_k127_5738666_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000429 144.0
HKD2_k127_5738666_6 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000000000005034 71.0
HKD2_k127_5738801_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K12142,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.6.5.3 1.136e-256 817.0
HKD2_k127_5738801_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 1.222e-244 774.0
HKD2_k127_5738801_10 Ni2 binding GTPase involved in regulation of expression and maturation of urease and hydrogenase K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 345.0
HKD2_k127_5738801_11 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 337.0
HKD2_k127_5738801_12 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 342.0
HKD2_k127_5738801_13 Belongs to the complex I 20 kDa subunit family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 304.0
HKD2_k127_5738801_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
HKD2_k127_5738801_15 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000006574 191.0
HKD2_k127_5738801_16 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000001752 179.0
HKD2_k127_5738801_17 spore germination K00442,K08315 - 3.4.23.51 0.000000000000000000000000000000000002442 154.0
HKD2_k127_5738801_18 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000002974 138.0
HKD2_k127_5738801_19 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000007957 85.0
HKD2_k127_5738801_2 Nickel-dependent hydrogenase K14126 - 1.8.98.5 4.738e-217 683.0
HKD2_k127_5738801_20 hydrogenase maturation protease - - - 0.00000000007709 66.0
HKD2_k127_5738801_21 - - - - 0.00000000435 64.0
HKD2_k127_5738801_3 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 580.0
HKD2_k127_5738801_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 574.0
HKD2_k127_5738801_5 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 552.0
HKD2_k127_5738801_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 491.0
HKD2_k127_5738801_7 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 433.0
HKD2_k127_5738801_8 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 378.0
HKD2_k127_5738801_9 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 357.0
HKD2_k127_580165_0 DEAD DEAH box helicase K06877 - - 1.587e-290 928.0
HKD2_k127_580165_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.14e-256 802.0
HKD2_k127_580165_2 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 541.0
HKD2_k127_580165_3 spermidine synthase activity K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 396.0
HKD2_k127_580165_4 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 303.0
HKD2_k127_580165_5 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000003027 136.0
HKD2_k127_580165_6 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.000000000000000000000000000000005099 134.0
HKD2_k127_580165_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000006864 126.0
HKD2_k127_580165_8 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000001072 102.0
HKD2_k127_580165_9 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000003745 102.0
HKD2_k127_5822028_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1104.0
HKD2_k127_5822028_1 ABC transporter permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 501.0
HKD2_k127_5822028_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000008126 164.0
HKD2_k127_5822028_11 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.00000000000000000000000000000002257 143.0
HKD2_k127_5822028_13 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000005779 75.0
HKD2_k127_5822028_14 EXOIII K02342 - 2.7.7.7 0.0000000001942 68.0
HKD2_k127_5822028_2 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 353.0
HKD2_k127_5822028_3 CBS domain containing protein K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 332.0
HKD2_k127_5822028_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006402 326.0
HKD2_k127_5822028_5 Iron ABC transporter substrate-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001392 291.0
HKD2_k127_5822028_6 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 266.0
HKD2_k127_5822028_7 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000004864 236.0
HKD2_k127_5822028_8 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000008997 216.0
HKD2_k127_5822028_9 KR domain - - - 0.000000000000000000000000000000000000000000000000000002767 199.0
HKD2_k127_583646_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 333.0
HKD2_k127_583646_1 signal transduction histidine kinase K07716 - 2.7.13.3 0.0000000000000000000000000000000000000477 166.0
HKD2_k127_583646_2 - - - - 0.000000000000000000000002205 106.0
HKD2_k127_583646_3 YMGG-like Gly-zipper - - - 0.0000000000000000000003958 102.0
HKD2_k127_59975_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 353.0
HKD2_k127_59975_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000007162 78.0
HKD2_k127_6036831_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000006841 153.0
HKD2_k127_6036831_1 Transposase - - - 0.0000000000000000000000000000000000003655 146.0
HKD2_k127_6064971_0 Thiamine pyrophosphate enzyme, central domain K03852 - 2.3.3.15 1.314e-271 842.0
HKD2_k127_6064971_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 397.0
HKD2_k127_6132342_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 9.671e-199 645.0
HKD2_k127_6132342_1 formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 393.0
HKD2_k127_6132342_2 Major Facilitator Superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 309.0
HKD2_k127_6178494_0 Large extracellular alpha-helical protein K06894 - - 0.0 1941.0
HKD2_k127_6178494_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1399.0
HKD2_k127_6178494_10 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 474.0
HKD2_k127_6178494_11 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 472.0
HKD2_k127_6178494_12 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 432.0
HKD2_k127_6178494_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K02381 GO:0001539,GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0016874,GO:0016877,GO:0016878,GO:0019538,GO:0031974,GO:0032991,GO:0036211,GO:0040011,GO:0042709,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0046777,GO:0048870,GO:0051179,GO:0051674,GO:0070013,GO:0071704,GO:0071973,GO:0097588,GO:1901564,GO:1902494 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
HKD2_k127_6178494_14 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 432.0
HKD2_k127_6178494_15 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 422.0
HKD2_k127_6178494_16 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 414.0
HKD2_k127_6178494_17 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 410.0
HKD2_k127_6178494_18 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 402.0
HKD2_k127_6178494_19 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 399.0
HKD2_k127_6178494_2 Required for chromosome condensation and partitioning K03529 - - 3.452e-243 794.0
HKD2_k127_6178494_20 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 422.0
HKD2_k127_6178494_21 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 393.0
HKD2_k127_6178494_22 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 372.0
HKD2_k127_6178494_23 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 378.0
HKD2_k127_6178494_24 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 360.0
HKD2_k127_6178494_25 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
HKD2_k127_6178494_26 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
HKD2_k127_6178494_27 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 327.0
HKD2_k127_6178494_28 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 320.0
HKD2_k127_6178494_29 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 282.0
HKD2_k127_6178494_3 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 7.166e-203 659.0
HKD2_k127_6178494_30 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002114 282.0
HKD2_k127_6178494_31 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000002698 265.0
HKD2_k127_6178494_32 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001237 258.0
HKD2_k127_6178494_33 beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000004782 260.0
HKD2_k127_6178494_34 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000006659 252.0
HKD2_k127_6178494_35 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001986 232.0
HKD2_k127_6178494_36 PFAM thioesterase superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000002247 205.0
HKD2_k127_6178494_37 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000002659 209.0
HKD2_k127_6178494_38 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000104 205.0
HKD2_k127_6178494_39 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000006237 204.0
HKD2_k127_6178494_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 599.0
HKD2_k127_6178494_40 KR domain K00059,K21883 - 1.1.1.100,1.1.1.401 0.0000000000000000000000000000000000000000000000000001508 199.0
HKD2_k127_6178494_41 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000001547 180.0
HKD2_k127_6178494_42 Prolyl-tRNA synthetase K03976 - - 0.000000000000000000000000000000000000000000000004068 177.0
HKD2_k127_6178494_43 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000002603 163.0
HKD2_k127_6178494_44 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000000006931 162.0
HKD2_k127_6178494_45 Uncharacterized ACR, COG1399 K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000005975 151.0
HKD2_k127_6178494_46 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000001133 148.0
HKD2_k127_6178494_47 17 kDa outer membrane surface antigen - - - 0.000000000000000000000000000000000003378 143.0
HKD2_k127_6178494_48 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000007679 151.0
HKD2_k127_6178494_49 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000001874 136.0
HKD2_k127_6178494_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 598.0
HKD2_k127_6178494_50 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000002527 133.0
HKD2_k127_6178494_51 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000001828 132.0
HKD2_k127_6178494_52 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000143 120.0
HKD2_k127_6178494_53 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000002565 133.0
HKD2_k127_6178494_54 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000161 121.0
HKD2_k127_6178494_55 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000003069 110.0
HKD2_k127_6178494_56 THIoesterase K18700 - 3.1.2.29 0.00000000000000000000001077 110.0
HKD2_k127_6178494_57 PFAM Fimbrial assembly family protein K02662,K02663 - - 0.0000000000000000000000836 104.0
HKD2_k127_6178494_58 Subtilase family - - - 0.00000000000000000003056 107.0
HKD2_k127_6178494_59 Ribosomal L32p protein family K02911 - - 0.0000000000000000001733 89.0
HKD2_k127_6178494_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K01497,K02858,K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 580.0
HKD2_k127_6178494_60 Protein of unknown function (DUF2892) - - - 0.000000000000000002741 86.0
HKD2_k127_6178494_61 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.00000000000003245 86.0
HKD2_k127_6178494_62 Putative zinc-finger - - - 0.0000000000001731 74.0
HKD2_k127_6178494_63 EF-hand domain pair - - - 0.0000000000002137 77.0
HKD2_k127_6178494_64 domain, Protein - - - 0.00000000000114 82.0
HKD2_k127_6178494_65 protein transport across the cell outer membrane K02246,K08084 - - 0.00000000001454 72.0
HKD2_k127_6178494_67 YwiC-like protein - - - 0.000000007937 66.0
HKD2_k127_6178494_69 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000312 59.0
HKD2_k127_6178494_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 564.0
HKD2_k127_6178494_70 pilus assembly protein PilW - - - 0.000005733 56.0
HKD2_k127_6178494_71 Psort location CytoplasmicMembrane, score - - - 0.000321 51.0
HKD2_k127_6178494_8 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 542.0
HKD2_k127_6178494_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 518.0
HKD2_k127_629453_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 413.0
HKD2_k127_629453_1 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000002005 109.0
HKD2_k127_6426261_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1275.0
HKD2_k127_6426261_1 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 359.0
HKD2_k127_6426261_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000218 88.0
HKD2_k127_6426261_11 PFAM Pentapeptide repeats (8 copies) - - - 0.00000003783 59.0
HKD2_k127_6426261_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 338.0
HKD2_k127_6426261_3 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 302.0
HKD2_k127_6426261_4 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000003371 245.0
HKD2_k127_6426261_5 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000005545 234.0
HKD2_k127_6426261_6 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
HKD2_k127_6426261_7 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000000000002858 218.0
HKD2_k127_6426261_8 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000206 194.0
HKD2_k127_6426261_9 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000001652 167.0
HKD2_k127_6431196_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 448.0
HKD2_k127_6431196_1 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 301.0
HKD2_k127_6431196_2 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 293.0
HKD2_k127_6431196_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000003059 226.0
HKD2_k127_6431196_4 BON domain K04065 - - 0.000000000000001142 85.0
HKD2_k127_6437796_0 PFAM binding-protein-dependent transport systems inner membrane component K10233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 484.0
HKD2_k127_6437796_1 ABC transporter substrate-binding protein K02027,K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 450.0
HKD2_k127_6437796_2 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 297.0
HKD2_k127_6437796_3 PFAM binding-protein-dependent transport systems inner membrane component K10234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007191 269.0
HKD2_k127_6437796_4 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000001659 74.0
HKD2_k127_6446153_0 Acetamidase formamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 552.0
HKD2_k127_6446153_1 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 505.0
HKD2_k127_6446153_2 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 373.0
HKD2_k127_6446153_3 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 374.0
HKD2_k127_6446153_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 303.0
HKD2_k127_6446153_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005859 273.0
HKD2_k127_6446153_7 - - - - 0.000003837 53.0
HKD2_k127_6446153_8 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway - - - 0.000005463 53.0
HKD2_k127_6463542_0 DEAD DEAH box K03724 - - 0.0 1485.0
HKD2_k127_6463542_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 487.0
HKD2_k127_6463542_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 401.0
HKD2_k127_6463542_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
HKD2_k127_6463542_4 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000008944 234.0
HKD2_k127_6463542_5 Protein conserved in bacteria - - - 0.0000000000000000000000000004643 126.0
HKD2_k127_6468837_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000008325 238.0
HKD2_k127_6468837_1 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000005825 160.0
HKD2_k127_6468837_2 RNA recognition motif - - - 0.000000000000000000000000000000000000001007 151.0
HKD2_k127_6468837_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000008997 94.0
HKD2_k127_6468837_4 Lrp/AsnC ligand binding domain - - - 0.00001211 54.0
HKD2_k127_6470650_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1023.0
HKD2_k127_6470650_1 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 4.399e-296 930.0
HKD2_k127_6470650_10 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 424.0
HKD2_k127_6470650_11 Chalcone and stilbene synthases, C-terminal domain K16424 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 404.0
HKD2_k127_6470650_12 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 403.0
HKD2_k127_6470650_13 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 355.0
HKD2_k127_6470650_14 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 355.0
HKD2_k127_6470650_15 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 340.0
HKD2_k127_6470650_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 334.0
HKD2_k127_6470650_17 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 349.0
HKD2_k127_6470650_18 Hydrogenase expression formation protein (HypE) K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 332.0
HKD2_k127_6470650_19 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 340.0
HKD2_k127_6470650_2 PFAM Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 550.0
HKD2_k127_6470650_20 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 336.0
HKD2_k127_6470650_21 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 318.0
HKD2_k127_6470650_22 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 315.0
HKD2_k127_6470650_23 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 298.0
HKD2_k127_6470650_24 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 287.0
HKD2_k127_6470650_25 ABC 3 transport family K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001504 274.0
HKD2_k127_6470650_26 AAA domain, putative AbiEii toxin, Type IV TA system K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001138 263.0
HKD2_k127_6470650_27 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
HKD2_k127_6470650_28 TIGRFAM geranylgeranyl reductase K21401 - 1.3.99.38 0.000000000000000000000000000000000000000000000000000000000000000000002674 255.0
HKD2_k127_6470650_29 - - - - 0.000000000000000000000000000000000000000000000000000000000000002662 235.0
HKD2_k127_6470650_3 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 541.0
HKD2_k127_6470650_30 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000001624 228.0
HKD2_k127_6470650_31 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000007452 229.0
HKD2_k127_6470650_32 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000008707 239.0
HKD2_k127_6470650_33 geranylgeranyl reductase activity - - - 0.000000000000000000000000000000000000000000000000000000002916 214.0
HKD2_k127_6470650_34 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000003886 203.0
HKD2_k127_6470650_35 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000004183 181.0
HKD2_k127_6470650_36 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000002083 191.0
HKD2_k127_6470650_37 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000001174 178.0
HKD2_k127_6470650_38 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000003115 158.0
HKD2_k127_6470650_39 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000001542 147.0
HKD2_k127_6470650_4 Trypsin K08070,K08372 - 1.3.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 490.0
HKD2_k127_6470650_40 Thioredoxin-like - - - 0.000000000000000000000000000000000008895 147.0
HKD2_k127_6470650_41 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000155 141.0
HKD2_k127_6470650_42 Peptidase S46 - - - 0.0000000000000000000000000000000007004 148.0
HKD2_k127_6470650_43 PFAM Iron permease FTR1 - - - 0.000000000000000000000000000000009199 147.0
HKD2_k127_6470650_44 SMART Signal transduction response regulator, receiver domain - - - 0.0000000000000000000000000000001467 134.0
HKD2_k127_6470650_45 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000000001673 129.0
HKD2_k127_6470650_46 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000005172 124.0
HKD2_k127_6470650_47 Ferric uptake regulator family K03711 - - 0.00000000000000000000001763 105.0
HKD2_k127_6470650_48 Evidence 5 No homology to any previously reported sequences K09005 - - 0.000000000000000000002326 107.0
HKD2_k127_6470650_49 TonB C terminal K03832 - - 0.000000000000000000004225 105.0
HKD2_k127_6470650_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 490.0
HKD2_k127_6470650_50 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - GO:0000003,GO:0000226,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005829,GO:0006950,GO:0006970,GO:0006996,GO:0007010,GO:0007017,GO:0007275,GO:0008150,GO:0008360,GO:0009628,GO:0009651,GO:0009653,GO:0009791,GO:0009826,GO:0009888,GO:0009908,GO:0009965,GO:0009987,GO:0010016,GO:0010026,GO:0010090,GO:0010091,GO:0010154,GO:0010482,GO:0010494,GO:0010769,GO:0012505,GO:0016043,GO:0016049,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022613,GO:0022618,GO:0030154,GO:0030856,GO:0031128,GO:0031129,GO:0031984,GO:0032501,GO:0032502,GO:0032989,GO:0032991,GO:0034063,GO:0034622,GO:0035770,GO:0036464,GO:0040007,GO:0042802,GO:0042803,GO:0042814,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045595,GO:0045604,GO:0045682,GO:0046983,GO:0048366,GO:0048367,GO:0048437,GO:0048444,GO:0048468,GO:0048530,GO:0048589,GO:0048608,GO:0048731,GO:0048827,GO:0048831,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051239,GO:0051302,GO:0060284,GO:0060560,GO:0061458,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071826,GO:0071840,GO:0090558,GO:0090567,GO:0090626,GO:0090696,GO:0090697,GO:0090698,GO:0098791,GO:0099402,GO:1905392,GO:1990904,GO:2000024,GO:2000026,GO:2000039 - 0.000000000428 68.0
HKD2_k127_6470650_51 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.000002004 59.0
HKD2_k127_6470650_52 TIGRFAM TonB K03832 - - 0.00001215 56.0
HKD2_k127_6470650_53 Outer membrane lipoprotein - - - 0.0001577 53.0
HKD2_k127_6470650_54 Sulfotransferase family - - - 0.0004736 50.0
HKD2_k127_6470650_55 SNARE associated Golgi protein - - - 0.0008264 43.0
HKD2_k127_6470650_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02049,K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 462.0
HKD2_k127_6470650_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 444.0
HKD2_k127_6470650_8 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 449.0
HKD2_k127_6470650_9 Glycosyl transferases group 1 K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 422.0
HKD2_k127_6471409_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000002443 151.0
HKD2_k127_6471409_1 Transposase - - - 0.00000000000000000000000000000009697 130.0
HKD2_k127_6471409_2 reverse transcriptase - - - 0.0000000000000009852 78.0
HKD2_k127_6471409_3 transposition - - - 0.000008618 52.0
HKD2_k127_6480756_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1300.0
HKD2_k127_6480756_1 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 589.0
HKD2_k127_6480756_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
HKD2_k127_6480756_11 Uridine 5-monophosphate K13421 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016036,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896,GO:0051716,GO:0071496 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000002947 185.0
HKD2_k127_6480756_12 Nitroreductase family - - - 0.00000000000000000000000000000000004368 144.0
HKD2_k127_6480756_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K04764 - - 0.0000000000000000000000000000001634 127.0
HKD2_k127_6480756_14 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000006561 111.0
HKD2_k127_6480756_15 - - - - 0.000000000000000000006683 96.0
HKD2_k127_6480756_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000004447 82.0
HKD2_k127_6480756_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 567.0
HKD2_k127_6480756_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 572.0
HKD2_k127_6480756_4 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 517.0
HKD2_k127_6480756_5 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 473.0
HKD2_k127_6480756_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 385.0
HKD2_k127_6480756_7 PFAM Haloacid dehalogenase domain protein hydrolase K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 302.0
HKD2_k127_6480756_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008952 282.0
HKD2_k127_6480756_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000005084 265.0
HKD2_k127_6482620_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K14189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 361.0
HKD2_k127_6482620_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004379 270.0
HKD2_k127_6482620_2 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000004493 237.0
HKD2_k127_6482620_3 OsmC-like protein - - - 0.0000000000000000000000000000000000000001039 156.0
HKD2_k127_6482620_4 - - - - 0.00000000000000000002623 94.0
HKD2_k127_6482620_5 TIGRFAM Molybdopterin-guanine dinucleotide biosynthesis protein B K03753,K13818 - 2.7.7.77 0.000008581 51.0
HKD2_k127_6482620_6 Uncharacterized protein conserved in archaea (DUF2096) - - - 0.0001577 50.0
HKD2_k127_6484400_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 458.0
HKD2_k127_6484400_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002705 274.0
HKD2_k127_6484400_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000023 150.0
HKD2_k127_6484400_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000002925 142.0
HKD2_k127_6484400_4 Protein conserved in bacteria K07465 - - 0.000000000000000000001741 104.0
HKD2_k127_6484400_5 Recombinase zinc beta ribbon domain K06400 - - 0.00001443 53.0
HKD2_k127_6493826_0 - - - - 1.086e-215 683.0
HKD2_k127_6493826_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K18030 - 1.17.2.1 0.000004367 48.0
HKD2_k127_6524161_0 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 457.0
HKD2_k127_6524161_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000002201 221.0
HKD2_k127_6524161_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000002477 220.0
HKD2_k127_6524161_3 PFAM cyclase family protein K07130 - 3.5.1.9 0.000000000000000000000000000000000000004475 163.0
HKD2_k127_6524161_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000004293 148.0
HKD2_k127_6524161_5 Gram-negative-bacterium-type cell wall biogenesis - - - 0.0000000000000000000000000000000000002743 151.0
HKD2_k127_6524161_6 mechanosensitive ion channel - - - 0.0001659 51.0
HKD2_k127_6526471_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 584.0
HKD2_k127_6526471_1 Family of unknown function (DUF438) K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 550.0
HKD2_k127_6526471_10 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009699 271.0
HKD2_k127_6526471_11 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000004779 231.0
HKD2_k127_6526471_12 Belongs to the metal hydrolase YfiT family - - - 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
HKD2_k127_6526471_13 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000000008515 202.0
HKD2_k127_6526471_14 Pfam:DUF59 K02612 - - 0.000000000000000000000000000000000000003372 148.0
HKD2_k127_6526471_15 Asp Glu hydantoin racemase - - - 0.000000000000000000000000000000000000005654 155.0
HKD2_k127_6526471_16 Transcriptional regulator K02624,K13641 - - 0.00000000000000000000000000000000000001851 159.0
HKD2_k127_6526471_17 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000009233 146.0
HKD2_k127_6526471_18 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000009459 137.0
HKD2_k127_6526471_19 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000000002707 133.0
HKD2_k127_6526471_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 533.0
HKD2_k127_6526471_20 membrane K07794 - - 0.000000000000000000001385 100.0
HKD2_k127_6526471_21 hydrogenase maturation protease K03605 - - 0.0000000000001511 74.0
HKD2_k127_6526471_22 PFAM 4Fe-4S K14108 - - 0.0002199 50.0
HKD2_k127_6526471_23 Protein of unknown function (DUF1344) - - - 0.0004156 47.0
HKD2_k127_6526471_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 473.0
HKD2_k127_6526471_4 Isocitrate isopropylmalate dehydrogenase K00030,K00031,K00052 - 1.1.1.41,1.1.1.42,1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 443.0
HKD2_k127_6526471_5 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 377.0
HKD2_k127_6526471_6 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 356.0
HKD2_k127_6526471_7 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 351.0
HKD2_k127_6526471_8 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 306.0
HKD2_k127_6526471_9 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 304.0
HKD2_k127_654354_0 thiamine transport K02011 - - 6.368e-247 775.0
HKD2_k127_654354_1 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 612.0
HKD2_k127_654354_10 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000001679 203.0
HKD2_k127_654354_11 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000001728 156.0
HKD2_k127_654354_12 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.00000000000000000000000000000000000001992 155.0
HKD2_k127_654354_2 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 526.0
HKD2_k127_654354_3 ABC transporter permease K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 507.0
HKD2_k127_654354_4 glycerophosphodiester transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 413.0
HKD2_k127_654354_5 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 421.0
HKD2_k127_654354_6 ATPases associated with a variety of cellular activities K02010,K11072 - 3.6.3.30,3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 336.0
HKD2_k127_654354_7 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 302.0
HKD2_k127_654354_8 ABC transporter permease K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004505 276.0
HKD2_k127_654354_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000004981 230.0
HKD2_k127_6544961_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.163e-304 956.0
HKD2_k127_6544961_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.051e-218 708.0
HKD2_k127_6544961_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 372.0
HKD2_k127_6544961_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 347.0
HKD2_k127_6544961_4 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 334.0
HKD2_k127_6544961_5 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000002298 213.0
HKD2_k127_6544961_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000001433 192.0
HKD2_k127_6544961_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000001236 143.0
HKD2_k127_6554517_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 3.302e-243 765.0
HKD2_k127_6554517_1 Sulfate permease family - - - 9.132e-235 739.0
HKD2_k127_6554517_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 463.0
HKD2_k127_6554517_3 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 315.0
HKD2_k127_6554517_4 Cysteine rich repeat - - - 0.00000000009468 68.0
HKD2_k127_6554517_5 Peptidase M16 domain protein K07263 - - 0.00008326 45.0
HKD2_k127_6563537_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.832e-275 865.0
HKD2_k127_6563537_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 5.939e-211 675.0
HKD2_k127_6563537_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 343.0
HKD2_k127_6563537_11 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 343.0
HKD2_k127_6563537_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 291.0
HKD2_k127_6563537_13 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000009147 212.0
HKD2_k127_6563537_14 Competence protein - - - 0.0000000000000000000000000000000000003981 150.0
HKD2_k127_6563537_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.000000000000000000000000000000000000659 146.0
HKD2_k127_6563537_16 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000004786 135.0
HKD2_k127_6563537_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000001148 125.0
HKD2_k127_6563537_18 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000004745 127.0
HKD2_k127_6563537_19 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000006594 118.0
HKD2_k127_6563537_2 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 553.0
HKD2_k127_6563537_20 Two component regulator propeller - - - 0.00000000000000001021 96.0
HKD2_k127_6563537_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 531.0
HKD2_k127_6563537_4 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 473.0
HKD2_k127_6563537_5 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 477.0
HKD2_k127_6563537_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 435.0
HKD2_k127_6563537_7 PUA domain K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 422.0
HKD2_k127_6563537_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 398.0
HKD2_k127_6563537_9 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 387.0
HKD2_k127_6582560_0 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000003251 171.0
HKD2_k127_6582560_1 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000002008 167.0
HKD2_k127_6604330_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 546.0
HKD2_k127_6604330_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 496.0
HKD2_k127_6604330_10 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 321.0
HKD2_k127_6604330_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 309.0
HKD2_k127_6604330_12 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
HKD2_k127_6604330_13 TRAP transporter, solute receptor (TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000007285 204.0
HKD2_k127_6604330_14 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000002176 197.0
HKD2_k127_6604330_15 Transcriptional regulator IclR K13641 - - 0.000000000000000000000000000000000000000000001003 178.0
HKD2_k127_6604330_16 Transcriptional regulator IclR K13641 - - 0.000000000000000000000000000000000000000001487 166.0
HKD2_k127_6604330_17 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000005453 154.0
HKD2_k127_6604330_18 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000005575 110.0
HKD2_k127_6604330_19 FAD binding domain - - - 0.00000000000000001934 87.0
HKD2_k127_6604330_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 481.0
HKD2_k127_6604330_20 Tripartite tricarboxylate transporter TctB family - - - 0.000000000004473 75.0
HKD2_k127_6604330_21 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000001055 65.0
HKD2_k127_6604330_22 membrane K07794 - - 0.000003768 55.0
HKD2_k127_6604330_3 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 464.0
HKD2_k127_6604330_4 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 460.0
HKD2_k127_6604330_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 391.0
HKD2_k127_6604330_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 364.0
HKD2_k127_6604330_7 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 372.0
HKD2_k127_6604330_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 351.0
HKD2_k127_6604330_9 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 341.0
HKD2_k127_6648300_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 5.314e-223 702.0
HKD2_k127_6648300_1 Spermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
HKD2_k127_6648300_2 chain release factor K15034 - - 0.0000000000000000000000000000000000000001475 154.0
HKD2_k127_6648300_3 SMART Water Stress and Hypersensitive response - - - 0.00000000000005947 74.0
HKD2_k127_6681054_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.386e-225 706.0
HKD2_k127_6681054_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 542.0
HKD2_k127_6681054_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 537.0
HKD2_k127_6681054_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 367.0
HKD2_k127_6681054_4 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 260.0
HKD2_k127_6681054_5 - - - - 0.000000000001359 72.0
HKD2_k127_6689529_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001457 271.0
HKD2_k127_6689529_1 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000001834 252.0
HKD2_k127_6689529_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000001142 141.0
HKD2_k127_6706293_0 CBS domain containing protein K00974 - 2.7.7.72 9.673e-247 790.0
HKD2_k127_6706293_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 1.124e-206 652.0
HKD2_k127_6706293_2 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 494.0
HKD2_k127_6706293_3 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000006171 211.0
HKD2_k127_6706293_4 Virulence factor BrkB K07058 - - 0.0000000000001107 81.0
HKD2_k127_6714171_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000001021 196.0
HKD2_k127_6746046_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 405.0
HKD2_k127_6746046_1 AsmA family K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 359.0
HKD2_k127_6746046_2 Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 269.0
HKD2_k127_6746046_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000472 215.0
HKD2_k127_6746046_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000007126 215.0
HKD2_k127_6746046_5 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000004738 155.0
HKD2_k127_6746046_6 Protein of unknown function (DUF992) - - - 0.000000000000000000000000000004977 126.0
HKD2_k127_6747089_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1797.0
HKD2_k127_6747089_1 Belongs to the binding-protein-dependent transport system permease family K01995 - - 3.204e-261 822.0
HKD2_k127_6747089_10 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
HKD2_k127_6747089_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 365.0
HKD2_k127_6747089_12 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 345.0
HKD2_k127_6747089_13 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 327.0
HKD2_k127_6747089_14 intracellular protease amidase K18199 - 4.2.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
HKD2_k127_6747089_15 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
HKD2_k127_6747089_16 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000369 272.0
HKD2_k127_6747089_17 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002732 241.0
HKD2_k127_6747089_18 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000005165 222.0
HKD2_k127_6747089_19 ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000009605 221.0
HKD2_k127_6747089_2 STAS domain - - - 1.693e-217 690.0
HKD2_k127_6747089_20 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000009066 194.0
HKD2_k127_6747089_21 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.00000000000000000000000000000000000000001732 163.0
HKD2_k127_6747089_22 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000329 130.0
HKD2_k127_6747089_23 heme a metabolic process K02259 - - 0.00000000000000000000000009948 120.0
HKD2_k127_6747089_24 pyridoxamine 5'-phosphate K07005,K07006 - - 0.00000000000000000000002872 103.0
HKD2_k127_6747089_25 - - - - 0.00000000000000000001357 100.0
HKD2_k127_6747089_26 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000001189 66.0
HKD2_k127_6747089_27 - - - - 0.000000002846 68.0
HKD2_k127_6747089_28 HMGL-like - - - 0.00000003092 56.0
HKD2_k127_6747089_3 PFAM Major Facilitator Superfamily - - - 2.089e-208 658.0
HKD2_k127_6747089_4 Receptor family ligand binding region - - - 1.499e-194 612.0
HKD2_k127_6747089_5 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 484.0
HKD2_k127_6747089_6 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 452.0
HKD2_k127_6747089_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 449.0
HKD2_k127_6747089_8 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 434.0
HKD2_k127_6751700_0 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 406.0
HKD2_k127_6751700_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000001802 108.0
HKD2_k127_6771012_0 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000000000000000000000000001915 222.0
HKD2_k127_6771012_1 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
HKD2_k127_6771012_2 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000006696 184.0
HKD2_k127_6771012_3 Response regulator receiver domain - - - 0.000000000000000000001387 99.0
HKD2_k127_6771012_4 Nitroreductase family - - - 0.0001641 52.0
HKD2_k127_6796870_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.496e-206 653.0
HKD2_k127_6796870_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 358.0
HKD2_k127_6796870_2 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000003074 107.0
HKD2_k127_6796870_3 oxidation-reduction process - - - 0.000004244 53.0
HKD2_k127_6806699_0 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 529.0
HKD2_k127_6806699_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 465.0
HKD2_k127_6806699_2 ATPase associated with K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 389.0
HKD2_k127_6806699_3 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001238 273.0
HKD2_k127_6806699_4 oxidoreductase activity K07114,K16257 - - 0.000000000000000000000000000000000000000000000000000000000000000001208 261.0
HKD2_k127_6806699_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000001827 184.0
HKD2_k127_6806699_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000006002 139.0
HKD2_k127_6806699_7 tetratricopeptide repeat - - - 0.00000000000000000000004412 117.0
HKD2_k127_683382_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 586.0
HKD2_k127_683382_1 Catalyzes the synthesis of GMP from XMP K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 419.0
HKD2_k127_683382_2 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000008819 133.0
HKD2_k127_6870749_0 Belongs to the DEAD box helicase family K03732,K05592,K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 550.0
HKD2_k127_6870749_1 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 330.0
HKD2_k127_6870749_10 Cold shock K03704 - - 0.000000000000005799 78.0
HKD2_k127_6870749_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 331.0
HKD2_k127_6870749_3 RNA pseudouridylate synthase K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008172 279.0
HKD2_k127_6870749_4 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000881 224.0
HKD2_k127_6870749_5 regulatory protein, gntR - - - 0.000000000000000000000000000000000000000000000000000195 198.0
HKD2_k127_6870749_6 RNA recognition motif - - - 0.0000000000000000000000000000000000000000222 154.0
HKD2_k127_6870749_7 PFAM Mechanosensitive ion channel K03442 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000005883 116.0
HKD2_k127_6870749_8 PFAM regulatory protein ArsR K03892 - - 0.000000000000000000005264 97.0
HKD2_k127_6870749_9 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001877 94.0
HKD2_k127_6893964_0 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 552.0
HKD2_k127_6893964_1 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 474.0
HKD2_k127_6893964_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000004537 115.0
HKD2_k127_6893964_11 SPTR CopG domain protein DNA-binding domain protein - - - 0.000000000001521 71.0
HKD2_k127_6893964_12 - - - - 0.000000000006596 71.0
HKD2_k127_6893964_13 Membrane - - - 0.000002715 56.0
HKD2_k127_6893964_15 - - - - 0.0008146 43.0
HKD2_k127_6893964_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 469.0
HKD2_k127_6893964_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 437.0
HKD2_k127_6893964_4 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 433.0
HKD2_k127_6893964_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 406.0
HKD2_k127_6893964_6 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 408.0
HKD2_k127_6893964_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 308.0
HKD2_k127_6893964_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000008413 196.0
HKD2_k127_6893964_9 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000000000000000000000000267 165.0
HKD2_k127_6905080_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 306.0
HKD2_k127_6906048_0 transposition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 506.0
HKD2_k127_6906048_1 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000006839 115.0
HKD2_k127_693807_0 regulation of DNA-templated transcription, elongation - - - 5.123e-272 862.0
HKD2_k127_693807_1 ABC transporter transmembrane region K06147,K18893 - - 1.52e-264 826.0
HKD2_k127_693807_2 regulation of DNA-templated transcription, elongation - - - 1.464e-214 685.0
HKD2_k127_693807_3 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 367.0
HKD2_k127_693807_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 376.0
HKD2_k127_694805_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170,K19071 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 472.0
HKD2_k127_694805_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 462.0
HKD2_k127_694805_10 Multicopper oxidase K00368,K18683,K22348 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.16.3.3,1.7.2.1 0.000000004354 64.0
HKD2_k127_694805_11 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00000002557 59.0
HKD2_k127_694805_12 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00001262 49.0
HKD2_k127_694805_2 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 393.0
HKD2_k127_694805_4 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000121 171.0
HKD2_k127_694805_5 response regulator K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000000000000005209 164.0
HKD2_k127_694805_6 Histidine kinase - - - 0.00000000000000000000000000000000001366 157.0
HKD2_k127_694805_7 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000008278 96.0
HKD2_k127_694805_8 PAP2 superfamily C-terminal - - - 0.000000000000001267 84.0
HKD2_k127_694805_9 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000001615 72.0
HKD2_k127_6957897_0 Tripartite tricarboxylate transporter TctA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 559.0
HKD2_k127_6957897_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 484.0
HKD2_k127_6957897_11 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000008562 66.0
HKD2_k127_6957897_12 PD-(D/E)XK nuclease superfamily K09124 - - 0.000001602 58.0
HKD2_k127_6957897_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
HKD2_k127_6957897_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 347.0
HKD2_k127_6957897_4 amino acid transport K01713,K02030 - 4.2.1.51,4.2.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 288.0
HKD2_k127_6957897_5 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000002257 264.0
HKD2_k127_6957897_6 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000133 258.0
HKD2_k127_6957897_7 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002246 252.0
HKD2_k127_6957897_8 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001494 244.0
HKD2_k127_6957897_9 - - - - 0.000000000000000000000000000000000001148 141.0
HKD2_k127_701967_0 YHS domain K17686 - 3.6.3.54 0.0 1066.0
HKD2_k127_701967_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 539.0
HKD2_k127_701967_10 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000244 162.0
HKD2_k127_701967_11 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000004889 152.0
HKD2_k127_701967_12 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000004483 147.0
HKD2_k127_701967_13 Cytochrome c K02275 - 1.9.3.1 0.0000000000000000000000000000000000008618 146.0
HKD2_k127_701967_14 Cytochrome c K02275 - 1.9.3.1 0.00000000000000000000000000000000636 142.0
HKD2_k127_701967_15 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000005865 114.0
HKD2_k127_701967_16 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000001099 106.0
HKD2_k127_701967_17 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000001004 105.0
HKD2_k127_701967_18 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000004999 92.0
HKD2_k127_701967_19 monooxygenase activity K00688 - 2.4.1.1 0.0000000000003197 72.0
HKD2_k127_701967_2 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 469.0
HKD2_k127_701967_20 membrane protein (DUF2078) K08982 - - 0.000000000000518 72.0
HKD2_k127_701967_21 P-type ATPase K17686 - 3.6.3.54 0.0000000000005997 70.0
HKD2_k127_701967_23 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0002962 43.0
HKD2_k127_701967_3 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 452.0
HKD2_k127_701967_4 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 289.0
HKD2_k127_701967_5 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000000000000006172 207.0
HKD2_k127_701967_6 HAMP domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001391 218.0
HKD2_k127_701967_7 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000004088 196.0
HKD2_k127_701967_8 Thioredoxin-like K02199,K03671 - - 0.000000000000000000000000000000000000000000000000156 184.0
HKD2_k127_701967_9 - - - - 0.0000000000000000000000000000000000000000003739 163.0
HKD2_k127_7069297_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000004408 141.0
HKD2_k127_7081358_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009656 272.0
HKD2_k127_7081358_1 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000314 244.0
HKD2_k127_7081358_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000137 88.0
HKD2_k127_7293854_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 1.506e-230 717.0
HKD2_k127_7293854_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 463.0
HKD2_k127_7293854_10 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001303 278.0
HKD2_k127_7293854_11 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005375 273.0
HKD2_k127_7293854_12 Male sterility protein K22025 - 1.1.1.410 0.00000000000000000000000000000000000000000000000000000000000000000000002544 255.0
HKD2_k127_7293854_13 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000003728 254.0
HKD2_k127_7293854_14 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000002621 238.0
HKD2_k127_7293854_15 Outer membrane lipoprotein K05807,K08309 - - 0.00000000000000000000000000000000000000000000000000000000000006626 225.0
HKD2_k127_7293854_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000001875 219.0
HKD2_k127_7293854_17 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000003693 219.0
HKD2_k127_7293854_18 - - - - 0.00000000000000000000000000000000000000000000000000005615 213.0
HKD2_k127_7293854_19 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000001285 193.0
HKD2_k127_7293854_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 432.0
HKD2_k127_7293854_20 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000008851 185.0
HKD2_k127_7293854_21 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000998 165.0
HKD2_k127_7293854_22 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000001344 175.0
HKD2_k127_7293854_23 response regulator, receiver K03413 - - 0.0000000000000000000000000000000000000001003 163.0
HKD2_k127_7293854_24 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000007258 112.0
HKD2_k127_7293854_25 Haem-degrading - - - 0.000000000000000000000000003995 117.0
HKD2_k127_7293854_28 chemotaxis K02659,K03408 - - 0.00000000000687 73.0
HKD2_k127_7293854_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 347.0
HKD2_k127_7293854_30 CheC-like family K03410 - - 0.000000003212 66.0
HKD2_k127_7293854_31 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.00000003371 58.0
HKD2_k127_7293854_32 Sporulation and spore germination - - - 0.00000007365 63.0
HKD2_k127_7293854_33 Helix-hairpin-helix motif - - - 0.0000006359 56.0
HKD2_k127_7293854_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 349.0
HKD2_k127_7293854_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 332.0
HKD2_k127_7293854_6 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 320.0
HKD2_k127_7293854_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 295.0
HKD2_k127_7293854_8 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 301.0
HKD2_k127_7293854_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 299.0
HKD2_k127_7338857_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.164e-229 728.0
HKD2_k127_7338857_1 O-methyltransferase activity - - - 5.214e-208 671.0
HKD2_k127_7338857_10 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001515 261.0
HKD2_k127_7338857_11 FtsJ-like methyltransferase K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000008039 259.0
HKD2_k127_7338857_12 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000009519 232.0
HKD2_k127_7338857_13 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000003683 209.0
HKD2_k127_7338857_14 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000001594 184.0
HKD2_k127_7338857_15 PFAM response regulator receiver K11443 - - 0.00000000000000000000000000002165 124.0
HKD2_k127_7338857_16 Histidine kinase K07711 - 2.7.13.3 0.00000000000000002403 82.0
HKD2_k127_7338857_17 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000002924 79.0
HKD2_k127_7338857_18 - - - - 0.000000001237 66.0
HKD2_k127_7338857_19 Protein of unknown function (DUF1059) - - - 0.00000009069 57.0
HKD2_k127_7338857_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 507.0
HKD2_k127_7338857_3 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 506.0
HKD2_k127_7338857_4 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 472.0
HKD2_k127_7338857_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 452.0
HKD2_k127_7338857_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 355.0
HKD2_k127_7338857_7 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 327.0
HKD2_k127_7338857_8 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 324.0
HKD2_k127_7338857_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 319.0
HKD2_k127_737079_0 Beta-eliminating lyase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 320.0
HKD2_k127_737079_1 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000002799 136.0
HKD2_k127_737079_2 Dodecin K09165 - - 0.000000000000000002757 89.0
HKD2_k127_7552743_0 N-terminal TM domain of oligopeptide transport permease C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 321.0
HKD2_k127_7552743_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000009572 270.0
HKD2_k127_7552743_2 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
HKD2_k127_7552743_3 alcohol dehydrogenase K19954 - - 0.00000000000000000000000000000000000000000009673 168.0
HKD2_k127_7552743_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000004443 104.0
HKD2_k127_7552743_5 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000001133 101.0
HKD2_k127_7597987_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.338e-239 744.0
HKD2_k127_7597987_1 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 554.0
HKD2_k127_7617799_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 457.0
HKD2_k127_7617799_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001601 279.0
HKD2_k127_7617799_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001357 270.0
HKD2_k127_7617799_3 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001425 285.0
HKD2_k127_7617799_4 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002684 252.0
HKD2_k127_7617799_5 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000001619 197.0
HKD2_k127_7617799_6 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006869,GO:0008144,GO:0008150,GO:0008289,GO:0008559,GO:0009987,GO:0010876,GO:0015221,GO:0015238,GO:0015399,GO:0015405,GO:0015437,GO:0015893,GO:0015920,GO:0016020,GO:0016021,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034040,GO:0034204,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042802,GO:0042908,GO:0042910,GO:0043167,GO:0043168,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0061024,GO:0065007,GO:0065008,GO:0071702,GO:0071840,GO:0071944,GO:0097035,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901265,GO:1901363,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000002438 49.0
HKD2_k127_7675665_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009051 248.0
HKD2_k127_7675665_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000006582 205.0
HKD2_k127_7675665_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000002587 171.0
HKD2_k127_7675665_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000001502 104.0
HKD2_k127_7677348_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 1.335e-245 766.0
HKD2_k127_7677348_1 binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
HKD2_k127_7677348_2 cyclic nucleotide binding K01420 - - 0.0000000000000000000000000000000000000000000000142 179.0
HKD2_k127_7677348_3 Major Facilitator Superfamily - - - 0.00000000000000000000000331 109.0
HKD2_k127_7677348_4 Cupin domain - - - 0.0000000000000000000003776 104.0
HKD2_k127_7684770_0 Protein of unknown function, DUF255 K06888 - - 0.0 1407.0
HKD2_k127_7684770_1 radical SAM domain protein K04034 - 1.21.98.3 4.086e-256 799.0
HKD2_k127_7684770_10 ABC transporter, ATP-binding protein K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 351.0
HKD2_k127_7684770_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 358.0
HKD2_k127_7684770_12 PFAM short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
HKD2_k127_7684770_13 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 317.0
HKD2_k127_7684770_14 PFAM Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 302.0
HKD2_k127_7684770_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007734 246.0
HKD2_k127_7684770_16 Beta-lactamase superfamily domain K03476 - - 0.00000000000000000000000000000000000000000000000000000000000000504 227.0
HKD2_k127_7684770_17 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000118 205.0
HKD2_k127_7684770_18 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000006625 215.0
HKD2_k127_7684770_19 ABC transporter K02029,K10037 - - 0.0000000000000000000000000000000000000000000000000000001702 202.0
HKD2_k127_7684770_2 CHAT domain - - - 2.136e-206 672.0
HKD2_k127_7684770_20 photosynthesis - - - 0.00000000000000000000000000000000000000000000000008005 185.0
HKD2_k127_7684770_22 ligase activity, forming carbon-carbon bonds K07402 - - 0.000000000000000000000000000000000000007483 149.0
HKD2_k127_7684770_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000005328 125.0
HKD2_k127_7684770_24 DoxX K03885,K16937 - 1.6.99.3,1.8.5.2 0.000000000000000000000007357 107.0
HKD2_k127_7684770_25 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000006259 88.0
HKD2_k127_7684770_26 - - - - 0.0000000000000002433 85.0
HKD2_k127_7684770_27 Cytochrome c - - - 0.0000000000000004921 81.0
HKD2_k127_7684770_28 sodium-dependent phosphate transmembrane transporter activity - - - 0.0000003694 62.0
HKD2_k127_7684770_29 Rhomboid family - - - 0.0000119 58.0
HKD2_k127_7684770_3 FAD binding domain K00278,K03388 - 1.4.3.16,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 617.0
HKD2_k127_7684770_4 C oxidoreductase subunit A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 449.0
HKD2_k127_7684770_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 435.0
HKD2_k127_7684770_6 cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 422.0
HKD2_k127_7684770_7 Belongs to the bacterial solute-binding protein 3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 399.0
HKD2_k127_7684770_8 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 398.0
HKD2_k127_7684770_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 385.0
HKD2_k127_7689612_0 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 1.852e-275 863.0
HKD2_k127_7689612_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 395.0
HKD2_k127_7689612_2 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005541 275.0
HKD2_k127_7695872_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 3.47e-210 664.0
HKD2_k127_7695872_1 PFAM ABC transporter related K01995,K01998 - - 7.262e-200 639.0
HKD2_k127_7695872_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 374.0
HKD2_k127_7695872_11 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 317.0
HKD2_k127_7695872_12 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 314.0
HKD2_k127_7695872_13 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002296 288.0
HKD2_k127_7695872_14 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009061 283.0
HKD2_k127_7695872_15 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001387 274.0
HKD2_k127_7695872_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007752 269.0
HKD2_k127_7695872_17 GAF domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004596 284.0
HKD2_k127_7695872_18 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001107 265.0
HKD2_k127_7695872_19 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006057 277.0
HKD2_k127_7695872_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 552.0
HKD2_k127_7695872_20 COG0559 Branched-chain amino acid ABC-type transport system, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007255 265.0
HKD2_k127_7695872_21 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000001461 260.0
HKD2_k127_7695872_22 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001267 261.0
HKD2_k127_7695872_23 Binding-protein-dependent transport system inner membrane component K02026,K10190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007914 265.0
HKD2_k127_7695872_24 Branched-chain amino acid transport K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000009305 239.0
HKD2_k127_7695872_25 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000001346 239.0
HKD2_k127_7695872_26 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000002371 227.0
HKD2_k127_7695872_27 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000007548 226.0
HKD2_k127_7695872_28 - - - - 0.000000000000000000000000000000000000000000000000000000000004883 213.0
HKD2_k127_7695872_29 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000002249 196.0
HKD2_k127_7695872_3 PFAM beta-lactamase domain protein K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 489.0
HKD2_k127_7695872_30 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000149 181.0
HKD2_k127_7695872_31 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000001514 177.0
HKD2_k127_7695872_32 Histidine kinase - - - 0.0000000000000000000000000000000000000000000008008 186.0
HKD2_k127_7695872_33 DinB family - - - 0.0000000000000000000000000000000000000000001666 168.0
HKD2_k127_7695872_34 heme binding - - - 0.0000000000000000000000000000000000004554 151.0
HKD2_k127_7695872_35 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000006571 152.0
HKD2_k127_7695872_36 Ferredoxin - - - 0.00000000000000000000000000004242 128.0
HKD2_k127_7695872_37 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000008012 118.0
HKD2_k127_7695872_38 Lecithin:cholesterol acyltransferase - - - 0.00000000000000000000001086 115.0
HKD2_k127_7695872_39 PFAM Rhodanese domain protein - - - 0.000000000000000000006024 96.0
HKD2_k127_7695872_4 Amidase, hydantoinase carbamoylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 472.0
HKD2_k127_7695872_41 Sec-independent protein translocase protein TatA K03116 - - 0.000000000000000002704 88.0
HKD2_k127_7695872_42 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.00000000000000003904 92.0
HKD2_k127_7695872_43 DinB superfamily - - - 0.0000000000000001645 88.0
HKD2_k127_7695872_44 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000004208 78.0
HKD2_k127_7695872_45 Rhodanese Homology Domain - - - 0.000000291 52.0
HKD2_k127_7695872_46 Fibronectin, type III domain - - - 0.0009931 50.0
HKD2_k127_7695872_5 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 467.0
HKD2_k127_7695872_6 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 449.0
HKD2_k127_7695872_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 421.0
HKD2_k127_7695872_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 427.0
HKD2_k127_7695872_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671,K22345 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9,4.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 413.0
HKD2_k127_7706923_0 cell adhesion involved in biofilm formation K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 376.0
HKD2_k127_7706923_1 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 364.0
HKD2_k127_7706923_2 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 327.0
HKD2_k127_7706923_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 312.0
HKD2_k127_7706923_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001889 230.0
HKD2_k127_7706923_5 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000009248 160.0
HKD2_k127_7706923_6 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07658,K18941 - - 0.0000000000000000001308 102.0
HKD2_k127_7706923_7 DinB superfamily - - - 0.00000000000000001264 88.0
HKD2_k127_7706923_8 ATP-dependent Clp protease adaptor protein ClpS - - - 0.00000000000008637 76.0
HKD2_k127_7719485_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 613.0
HKD2_k127_7719485_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 507.0
HKD2_k127_7719485_10 Carbon-nitrogen hydrolase K01459 - 3.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000255 261.0
HKD2_k127_7719485_11 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000005787 247.0
HKD2_k127_7719485_12 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000005217 232.0
HKD2_k127_7719485_13 PIN domain - - - 0.00000000000004039 76.0
HKD2_k127_7719485_2 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 508.0
HKD2_k127_7719485_3 COG0520 Selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 461.0
HKD2_k127_7719485_4 Catalyzes the dehydration of D-mannonate K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 437.0
HKD2_k127_7719485_5 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 431.0
HKD2_k127_7719485_6 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 361.0
HKD2_k127_7719485_7 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 343.0
HKD2_k127_7719485_8 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
HKD2_k127_7719485_9 (ABC) transporter, permease K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006118 271.0
HKD2_k127_7730831_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 537.0
HKD2_k127_7730831_1 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 517.0
HKD2_k127_7730831_10 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000485 198.0
HKD2_k127_7730831_12 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000003396 74.0
HKD2_k127_7730831_2 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 424.0
HKD2_k127_7730831_3 COG0001 Glutamate-1-semialdehyde aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 424.0
HKD2_k127_7730831_4 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 430.0
HKD2_k127_7730831_5 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 379.0
HKD2_k127_7730831_6 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 335.0
HKD2_k127_7730831_7 NAD binding K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 291.0
HKD2_k127_7730831_8 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
HKD2_k127_7730831_9 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 267.0
HKD2_k127_7732271_0 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 520.0
HKD2_k127_7732271_1 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.0000000000000000000000000000000000000000000000000000000007239 203.0
HKD2_k127_7732271_2 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000001043 194.0
HKD2_k127_7732271_3 membrane - - - 0.00000007497 59.0
HKD2_k127_7738665_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1245.0
HKD2_k127_7738665_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1028.0
HKD2_k127_7738665_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000009319 177.0
HKD2_k127_7738665_11 Regulatory protein GntR HTH K05799 - - 0.000000000000000000000000000004484 129.0
HKD2_k127_7738665_12 Cold shock K03704 - - 0.0000000000000000000001482 101.0
HKD2_k127_7738665_13 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000005226 92.0
HKD2_k127_7738665_15 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.00002242 48.0
HKD2_k127_7738665_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.367e-208 662.0
HKD2_k127_7738665_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 588.0
HKD2_k127_7738665_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 488.0
HKD2_k127_7738665_5 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 482.0
HKD2_k127_7738665_6 Aminotransferase class-V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 460.0
HKD2_k127_7738665_7 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 348.0
HKD2_k127_7738665_8 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
HKD2_k127_7738665_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000005748 196.0
HKD2_k127_7739660_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 2.932e-280 869.0
HKD2_k127_7739660_1 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 478.0
HKD2_k127_7739660_10 - - - - 0.000000002739 59.0
HKD2_k127_7739660_11 Protein of unknown function (DUF433) - - - 0.000006587 48.0
HKD2_k127_7739660_12 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0002171 48.0
HKD2_k127_7739660_2 nitrogen compound transport K02033 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 392.0
HKD2_k127_7739660_3 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 361.0
HKD2_k127_7739660_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 352.0
HKD2_k127_7739660_5 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 348.0
HKD2_k127_7739660_6 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 361.0
HKD2_k127_7739660_7 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000008599 234.0
HKD2_k127_7739660_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000001983 156.0
HKD2_k127_7739660_9 Antibiotic biosynthesis monooxygenase K01056 GO:0003674,GO:0003824 3.1.1.29 0.000000000000000000003429 98.0
HKD2_k127_7814836_0 Uncharacterized protein family (UPF0051) K09014 - - 1.54e-274 849.0
HKD2_k127_7814836_1 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 593.0
HKD2_k127_7814836_10 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000001123 221.0
HKD2_k127_7814836_11 KR domain K12420 - - 0.00000000000000000000000000000000000000000000000000003104 197.0
HKD2_k127_7814836_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000001318 180.0
HKD2_k127_7814836_13 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000005781 115.0
HKD2_k127_7814836_14 phosphorelay signal transduction system - - - 0.0000000000000000000002543 101.0
HKD2_k127_7814836_15 Protein of unknown function (DUF2283) - - - 0.00000000000001498 77.0
HKD2_k127_7814836_2 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 500.0
HKD2_k127_7814836_3 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 382.0
HKD2_k127_7814836_4 FeS assembly protein SufD K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 383.0
HKD2_k127_7814836_5 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 293.0
HKD2_k127_7814836_6 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005041 261.0
HKD2_k127_7814836_7 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000009423 256.0
HKD2_k127_7814836_8 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000004869 257.0
HKD2_k127_7814836_9 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000001573 251.0
HKD2_k127_7817174_0 ATP ADP translocase K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 534.0
HKD2_k127_7817174_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 394.0
HKD2_k127_7817174_10 PFAM binding-protein-dependent transport systems inner membrane component K02026,K17331 - - 0.00001512 48.0
HKD2_k127_7817174_2 PFAM Mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 396.0
HKD2_k127_7817174_3 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 365.0
HKD2_k127_7817174_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 345.0
HKD2_k127_7817174_5 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002084 277.0
HKD2_k127_7817174_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000001599 199.0
HKD2_k127_7817174_7 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000003852 178.0
HKD2_k127_7817174_8 PFAM Glycoside hydrolase, family 13 - - - 0.0000000000000000000000000000000008188 138.0
HKD2_k127_7817174_9 regulation of response to stimulus - - - 0.0000000000000002296 90.0
HKD2_k127_7834200_0 Pyridine nucleotide-disulphide oxidoreductase - - - 1.972e-216 693.0
HKD2_k127_7834200_1 alpha beta K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001241 259.0
HKD2_k127_7834200_2 - - - - 0.00000000000000000000000000007835 119.0
HKD2_k127_7834200_3 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000005482 104.0
HKD2_k127_7834200_4 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000002779 93.0
HKD2_k127_7834200_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000008227 85.0
HKD2_k127_7834200_6 - - - - 0.000001617 57.0
HKD2_k127_7873435_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 606.0
HKD2_k127_7873435_1 Peptidase S46 - - - 0.00000000000000000000000000001573 130.0
HKD2_k127_7876739_0 3-isopropylmalate dehydratase activity K01681,K01703,K17749,K20452 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0030312,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.3,4.2.1.33,4.2.1.35,4.2.1.85 2.242e-219 688.0
HKD2_k127_7876739_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 297.0
HKD2_k127_7876739_2 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002175 289.0
HKD2_k127_7876739_3 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000813 280.0
HKD2_k127_7876739_4 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000004429 223.0
HKD2_k127_7876739_5 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000009267 175.0
HKD2_k127_7882108_0 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 586.0
HKD2_k127_7882108_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 298.0
HKD2_k127_7882108_2 type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 306.0
HKD2_k127_7882108_3 General secretion pathway K02456 - - 0.00000000000000000000000000003912 126.0
HKD2_k127_7882108_4 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000008741 117.0
HKD2_k127_7882108_5 Pilus assembly protein, PilO K02664 - - 0.000000000008137 74.0
HKD2_k127_7882108_6 Pilus assembly protein - - - 0.00000000003073 77.0
HKD2_k127_7882108_7 PFAM Fimbrial assembly family protein K02663 - - 0.00000000003517 74.0
HKD2_k127_7887140_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0 1101.0
HKD2_k127_7887140_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 488.0
HKD2_k127_7887140_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21345 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000006209 181.0
HKD2_k127_7887140_11 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000001869 185.0
HKD2_k127_7887140_12 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000001011 146.0
HKD2_k127_7887140_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000002647 83.0
HKD2_k127_7887140_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 424.0
HKD2_k127_7887140_3 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 427.0
HKD2_k127_7887140_4 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 359.0
HKD2_k127_7887140_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 326.0
HKD2_k127_7887140_6 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 307.0
HKD2_k127_7887140_7 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 311.0
HKD2_k127_7887140_8 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004336 283.0
HKD2_k127_7887140_9 protein containing SIS (Sugar ISomerase) phosphosugar binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
HKD2_k127_788727_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 496.0
HKD2_k127_788727_1 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 353.0
HKD2_k127_788727_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000001409 196.0
HKD2_k127_788727_3 PFAM Integrase core domain - - - 0.000000000000945 70.0
HKD2_k127_7891458_0 cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 7.841e-217 693.0
HKD2_k127_7891458_1 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 9.841e-212 676.0
HKD2_k127_7891458_10 C4-dicarboxylate ABC transporter permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 332.0
HKD2_k127_7891458_11 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 305.0
HKD2_k127_7891458_12 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003661 273.0
HKD2_k127_7891458_13 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001498 275.0
HKD2_k127_7891458_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000003867 264.0
HKD2_k127_7891458_15 proteolysis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005748 244.0
HKD2_k127_7891458_16 ribonucleoside-diphosphate reductase activity K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000001326 229.0
HKD2_k127_7891458_17 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000002645 234.0
HKD2_k127_7891458_18 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000006321 227.0
HKD2_k127_7891458_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000005634 226.0
HKD2_k127_7891458_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 1.534e-202 640.0
HKD2_k127_7891458_20 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008305 221.0
HKD2_k127_7891458_21 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000002481 221.0
HKD2_k127_7891458_22 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000004966 206.0
HKD2_k127_7891458_23 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000002163 195.0
HKD2_k127_7891458_24 Belongs to the AAA ATPase family K13525 - - 0.000000000000000000000000000000000000000000000003781 185.0
HKD2_k127_7891458_25 - K00003,K00058,K01754,K04517,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,1.3.1.12,4.3.1.19 0.0000000000000000000000000000000000000000000116 169.0
HKD2_k127_7891458_26 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000001861 169.0
HKD2_k127_7891458_27 transcriptional K03710 - - 0.0000000000000000000000000000000000000000002333 171.0
HKD2_k127_7891458_28 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000006042 167.0
HKD2_k127_7891458_29 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000008044 159.0
HKD2_k127_7891458_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 617.0
HKD2_k127_7891458_30 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000005795 155.0
HKD2_k127_7891458_31 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000000000001592 134.0
HKD2_k127_7891458_32 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000004195 129.0
HKD2_k127_7891458_33 - - - - 0.00000000000000000000000000000006776 130.0
HKD2_k127_7891458_34 CoA binding domain K06929 - - 0.0000000000000000000000000000001082 128.0
HKD2_k127_7891458_35 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000003724 111.0
HKD2_k127_7891458_36 PFAM AsmA family protein K07289 - - 0.00000000000000000000000007932 124.0
HKD2_k127_7891458_37 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000002387 105.0
HKD2_k127_7891458_38 PFAM Methyltransferase type - - - 0.00000000000000000001169 102.0
HKD2_k127_7891458_39 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000002581 99.0
HKD2_k127_7891458_4 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 588.0
HKD2_k127_7891458_41 Methyltransferase domain - - - 0.00000000000001322 82.0
HKD2_k127_7891458_42 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.00000000000001502 87.0
HKD2_k127_7891458_43 - - - - 0.0000000000003319 74.0
HKD2_k127_7891458_44 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000003129 67.0
HKD2_k127_7891458_45 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000005747 64.0
HKD2_k127_7891458_46 - - - - 0.00000008658 59.0
HKD2_k127_7891458_47 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000001336 62.0
HKD2_k127_7891458_5 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 580.0
HKD2_k127_7891458_6 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 534.0
HKD2_k127_7891458_7 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 426.0
HKD2_k127_7891458_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 358.0
HKD2_k127_7891458_9 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 336.0
HKD2_k127_7895396_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0 1095.0
HKD2_k127_7895396_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1027.0
HKD2_k127_7895396_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002371 288.0
HKD2_k127_7895396_11 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000003958 244.0
HKD2_k127_7895396_12 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000001644 207.0
HKD2_k127_7895396_13 PFAM response regulator receiver K22010 - - 0.0000000000000000000000000000000000000000000009672 174.0
HKD2_k127_7895396_14 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000325 132.0
HKD2_k127_7895396_15 phosphorelay signal transduction system K07315 - 3.1.3.3 0.00000000000000000000000005263 118.0
HKD2_k127_7895396_16 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000001433 121.0
HKD2_k127_7895396_17 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.000000000000000003502 99.0
HKD2_k127_7895396_18 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K00575 - 2.1.1.80 0.000000000000002207 90.0
HKD2_k127_7895396_19 Response regulator receiver domain - - - 0.00000000003478 72.0
HKD2_k127_7895396_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.506e-311 969.0
HKD2_k127_7895396_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 3.344e-278 887.0
HKD2_k127_7895396_4 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.661e-277 861.0
HKD2_k127_7895396_5 Glycosyl hydrolases family 15 - - - 3.988e-266 832.0
HKD2_k127_7895396_6 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 9.793e-248 781.0
HKD2_k127_7895396_7 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 508.0
HKD2_k127_7895396_8 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 412.0
HKD2_k127_7895396_9 Phosphotransferase enzyme family K00700,K05343,K16146 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016310,GO:0034637,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046835,GO:0071704,GO:0071944,GO:1901576 2.4.1.18,2.7.1.175,3.2.1.1,5.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 323.0
HKD2_k127_7919375_0 PFAM RNA polymerase sigma factor 54, interaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 440.0
HKD2_k127_7919375_1 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000003918 88.0
HKD2_k127_7924404_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 614.0
HKD2_k127_7931728_0 - - - - 0.0000000000001786 78.0
HKD2_k127_7931728_1 Predicted membrane protein (DUF2231) - - - 0.0000000001291 68.0
HKD2_k127_7944522_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 510.0
HKD2_k127_7944522_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002811 293.0
HKD2_k127_7944522_2 ABC-type dipeptide transport system periplasmic component-like protein K02035,K15580 - - 0.000000001183 64.0
HKD2_k127_7965040_0 spermidine putrescine K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005259 268.0
HKD2_k127_7965040_1 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009646 251.0
HKD2_k127_7965040_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000001514 156.0
HKD2_k127_7965040_3 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000005051 153.0
HKD2_k127_7968547_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 2166.0
HKD2_k127_7968547_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1615.0
HKD2_k127_7968547_10 Ribosomal protein L33 K02913 - - 0.0000000000000000002418 88.0
HKD2_k127_7968547_11 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000003521 77.0
HKD2_k127_7968547_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000006303 70.0
HKD2_k127_7968547_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000003702 66.0
HKD2_k127_7968547_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1019.0
HKD2_k127_7968547_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 361.0
HKD2_k127_7968547_4 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 301.0
HKD2_k127_7968547_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000001292 243.0
HKD2_k127_7968547_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001864 234.0
HKD2_k127_7968547_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003606 216.0
HKD2_k127_7968547_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000004564 179.0
HKD2_k127_7968547_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000001449 156.0
HKD2_k127_7975654_0 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000005344 196.0
HKD2_k127_7975654_1 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000001954 139.0
HKD2_k127_7975654_2 - - - - 0.000000000000000000000001192 107.0
HKD2_k127_7975654_3 - - - - 0.000000000000000009116 85.0
HKD2_k127_7975654_4 Isochorismatase family - - - 0.0000000000000001915 87.0
HKD2_k127_7975654_5 Methyltransferase type 11 - - - 0.000000002282 66.0
HKD2_k127_7977988_0 TIGRFAM Ammonium transporter K03320 - - 5.479e-223 706.0
HKD2_k127_7977988_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 590.0
HKD2_k127_7977988_10 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 292.0
HKD2_k127_7977988_11 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000881 290.0
HKD2_k127_7977988_12 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006424 255.0
HKD2_k127_7977988_13 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000004242 236.0
HKD2_k127_7977988_14 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000007823 233.0
HKD2_k127_7977988_15 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000001135 219.0
HKD2_k127_7977988_16 ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000001202 226.0
HKD2_k127_7977988_17 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000001193 194.0
HKD2_k127_7977988_18 dna polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000002325 179.0
HKD2_k127_7977988_19 - - - - 0.00000000000000000000005898 101.0
HKD2_k127_7977988_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 541.0
HKD2_k127_7977988_20 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000004029 64.0
HKD2_k127_7977988_21 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00002545 50.0
HKD2_k127_7977988_3 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 506.0
HKD2_k127_7977988_4 ABC transporter substrate-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 410.0
HKD2_k127_7977988_5 Signal transduction histidine kinase, nitrogen specific, NtrB K07708,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 374.0
HKD2_k127_7977988_6 Male sterility protein K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 323.0
HKD2_k127_7977988_7 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 313.0
HKD2_k127_7977988_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 304.0
HKD2_k127_7977988_9 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 301.0
HKD2_k127_7992482_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 616.0
HKD2_k127_7992482_1 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 393.0
HKD2_k127_7992482_2 HTH-like domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 373.0
HKD2_k127_7992482_3 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000004989 196.0
HKD2_k127_7992482_4 Transposase - - - 0.00000000000000000000000000000000000006361 145.0
HKD2_k127_7992482_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000003957 152.0
HKD2_k127_7992482_6 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000008123 132.0
HKD2_k127_8021632_0 protein conserved in bacteria K07793 - - 4.135e-250 779.0
HKD2_k127_8021632_1 Dehydratase family K01687,K16786 - 4.2.1.9 2.994e-249 781.0
HKD2_k127_8021632_10 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 301.0
HKD2_k127_8021632_11 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 277.0
HKD2_k127_8021632_12 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 282.0
HKD2_k127_8021632_13 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000003892 249.0
HKD2_k127_8021632_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000009644 230.0
HKD2_k127_8021632_15 Vacuole effluxer Atg22 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000177 241.0
HKD2_k127_8021632_16 transcription activator K03707 - 3.5.99.2 0.00000000000000000000000000000000000000000000000000000000000000167 226.0
HKD2_k127_8021632_17 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000000000000006878 219.0
HKD2_k127_8021632_18 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000001836 223.0
HKD2_k127_8021632_19 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000006599 219.0
HKD2_k127_8021632_2 MmgE/PrpD family - - - 4.114e-211 679.0
HKD2_k127_8021632_20 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000008726 204.0
HKD2_k127_8021632_21 - - - - 0.000000000000000000000000000000000000000000000001297 181.0
HKD2_k127_8021632_22 2Fe-2S -binding domain protein K18029 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016725,GO:0019439,GO:0044237,GO:0044248,GO:0055114 1.17.2.1 0.00000000000000000000000000000000000000000001368 166.0
HKD2_k127_8021632_23 PFAM 4Fe-4S K00196 - - 0.000000000000000000000000000000000000001564 154.0
HKD2_k127_8021632_24 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000007387 140.0
HKD2_k127_8021632_25 MazG-like family - - - 0.00000000000000000000000000008355 119.0
HKD2_k127_8021632_26 - - - - 0.0000000000000000000000005632 105.0
HKD2_k127_8021632_27 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.000000000000000000000002768 120.0
HKD2_k127_8021632_28 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000006409 101.0
HKD2_k127_8021632_29 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000009219 80.0
HKD2_k127_8021632_3 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 603.0
HKD2_k127_8021632_30 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000008642 84.0
HKD2_k127_8021632_31 - - - - 0.0000000000001266 81.0
HKD2_k127_8021632_32 cheY-homologous receiver domain K07657 - - 0.00000000005174 73.0
HKD2_k127_8021632_33 Drug exporters of the RND superfamily - - - 0.00001868 49.0
HKD2_k127_8021632_34 Peptidase family M23 K21471 - - 0.0001147 45.0
HKD2_k127_8021632_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 539.0
HKD2_k127_8021632_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 466.0
HKD2_k127_8021632_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 436.0
HKD2_k127_8021632_7 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 414.0
HKD2_k127_8021632_8 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 398.0
HKD2_k127_8021632_9 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 399.0
HKD2_k127_80496_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 596.0
HKD2_k127_80496_1 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 458.0
HKD2_k127_80496_2 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 450.0
HKD2_k127_80496_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 444.0
HKD2_k127_80496_4 N-acyl-D-amino acid deacylase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 372.0
HKD2_k127_80496_5 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 328.0
HKD2_k127_80496_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005583 250.0
HKD2_k127_80496_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000001488 254.0
HKD2_k127_80496_8 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000001665 123.0
HKD2_k127_80496_9 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.00000002097 57.0
HKD2_k127_8072035_0 DNA replication proofreading K02336,K06877,K07501 - 2.7.7.7 2.55e-263 833.0
HKD2_k127_8072035_1 Peptidoglycan-binding domain 1 protein K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 566.0
HKD2_k127_8072035_10 Type II secretion system protein B - - - 0.0000000001263 71.0
HKD2_k127_8072035_2 PFAM Radical SAM K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 490.0
HKD2_k127_8072035_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 415.0
HKD2_k127_8072035_4 Methyltransferase domain K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000006331 194.0
HKD2_k127_8072035_5 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000003881 187.0
HKD2_k127_8072035_6 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000001824 177.0
HKD2_k127_8072035_7 histidine kinase A domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000501 127.0
HKD2_k127_8072035_9 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.0000000000000001575 89.0
HKD2_k127_8076447_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 304.0
HKD2_k127_8076447_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005455 251.0
HKD2_k127_8076447_2 SnoaL-like polyketide cyclase - - - 0.0000000000000002083 87.0
HKD2_k127_8116468_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1080.0
HKD2_k127_8116468_1 Belongs to the carbamoyltransferase HypF family K04656 - - 1.392e-287 913.0
HKD2_k127_8116468_10 solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000178 268.0
HKD2_k127_8116468_11 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 260.0
HKD2_k127_8116468_12 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000003446 225.0
HKD2_k127_8116468_13 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000404 223.0
HKD2_k127_8116468_14 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000008013 211.0
HKD2_k127_8116468_15 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000005246 202.0
HKD2_k127_8116468_16 response regulator - - - 0.0000000000000000000000000000000002241 151.0
HKD2_k127_8116468_17 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000002374 114.0
HKD2_k127_8116468_18 PFAM CheW domain protein K03408 - - 0.000000000000000000749 93.0
HKD2_k127_8116468_19 4Fe-4S dicluster domain K00124 - - 0.000000000000000001058 87.0
HKD2_k127_8116468_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 6.179e-222 702.0
HKD2_k127_8116468_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000004588 70.0
HKD2_k127_8116468_21 Two component signalling adaptor domain K03408 - - 0.0000001804 60.0
HKD2_k127_8116468_3 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 4.37e-213 666.0
HKD2_k127_8116468_4 hydrogenase expression formation protein K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 578.0
HKD2_k127_8116468_5 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 480.0
HKD2_k127_8116468_6 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 427.0
HKD2_k127_8116468_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 368.0
HKD2_k127_8116468_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 334.0
HKD2_k127_8116468_9 Nickel-dependent hydrogenase K15830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 302.0
HKD2_k127_8118989_0 Alanine dehydrogenase/PNT, C-terminal domain K00259 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009653,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030435,GO:0032502,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 499.0
HKD2_k127_8118989_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 412.0
HKD2_k127_8118989_2 Carbon-nitrogen hydrolase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 357.0
HKD2_k127_8118989_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 282.0
HKD2_k127_8118989_4 - - - - 0.00000000000000000000001107 116.0
HKD2_k127_8126083_0 PFAM 4Fe-4S K00184,K21308 - - 0.0 1181.0
HKD2_k127_8126083_1 aldehyde ferredoxin oxidoreductase activity K03738,K11389 - 1.2.7.5,1.2.7.6 1.372e-318 988.0
HKD2_k127_8126083_10 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 415.0
HKD2_k127_8126083_11 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 419.0
HKD2_k127_8126083_12 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 404.0
HKD2_k127_8126083_13 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 410.0
HKD2_k127_8126083_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 364.0
HKD2_k127_8126083_15 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 387.0
HKD2_k127_8126083_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 366.0
HKD2_k127_8126083_17 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 355.0
HKD2_k127_8126083_18 ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 346.0
HKD2_k127_8126083_19 Mandelate racemase muconate lactonizing enzyme, N-terminal domain K01683,K01684 - 4.2.1.5,4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 346.0
HKD2_k127_8126083_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 5.941e-295 925.0
HKD2_k127_8126083_20 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 332.0
HKD2_k127_8126083_21 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 342.0
HKD2_k127_8126083_22 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 324.0
HKD2_k127_8126083_23 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 323.0
HKD2_k127_8126083_24 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 314.0
HKD2_k127_8126083_25 PFAM aminotransferase, class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 313.0
HKD2_k127_8126083_26 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 303.0
HKD2_k127_8126083_27 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001693 286.0
HKD2_k127_8126083_28 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
HKD2_k127_8126083_29 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002515 256.0
HKD2_k127_8126083_3 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 4.305e-251 790.0
HKD2_k127_8126083_30 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001603 236.0
HKD2_k127_8126083_31 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000002898 246.0
HKD2_k127_8126083_32 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
HKD2_k127_8126083_33 Acetamidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000003962 231.0
HKD2_k127_8126083_34 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
HKD2_k127_8126083_35 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000002008 226.0
HKD2_k127_8126083_36 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001258 220.0
HKD2_k127_8126083_37 metal-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000003533 213.0
HKD2_k127_8126083_38 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.00000000000000000000000000000000000000000000000000000004881 204.0
HKD2_k127_8126083_39 6-phosphogluconate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000008204 199.0
HKD2_k127_8126083_4 Polysulphide reductase, NrfD K00185 - - 1.254e-217 684.0
HKD2_k127_8126083_40 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000009514 187.0
HKD2_k127_8126083_41 DinB superfamily K07552 - - 0.00000000000000000000000000000000000000000000004778 174.0
HKD2_k127_8126083_42 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000009093 172.0
HKD2_k127_8126083_43 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000004399 167.0
HKD2_k127_8126083_44 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000003313 152.0
HKD2_k127_8126083_45 - - - - 0.000000000000000000000000084 114.0
HKD2_k127_8126083_46 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000001879 113.0
HKD2_k127_8126083_47 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000209 106.0
HKD2_k127_8126083_48 Membrane - - - 0.00000000000000000154 91.0
HKD2_k127_8126083_49 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000002798 91.0
HKD2_k127_8126083_5 (ABC) transporter K15738 - - 1.079e-209 672.0
HKD2_k127_8126083_50 GIY-YIG catalytic domain protein K07461 - - 0.00000000000000001635 85.0
HKD2_k127_8126083_51 Regulatory protein, FmdB family - - - 0.00000000000000007085 84.0
HKD2_k127_8126083_52 - - - - 0.00000000000002125 79.0
HKD2_k127_8126083_53 Peptidase family S58 K01266 - 3.4.11.19 0.000000000009349 72.0
HKD2_k127_8126083_54 - - - - 0.0000000002601 70.0
HKD2_k127_8126083_55 - - - - 0.000000001302 63.0
HKD2_k127_8126083_57 - - - - 0.0002575 49.0
HKD2_k127_8126083_6 Chitobiase/beta-hexosaminidase C-terminal domain - - - 5.881e-209 670.0
HKD2_k127_8126083_7 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.453e-201 642.0
HKD2_k127_8126083_8 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 525.0
HKD2_k127_8126083_9 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 463.0
HKD2_k127_8159419_0 Glycosyltransferase like family 2 K00721 GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 426.0
HKD2_k127_8159419_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000007513 254.0
HKD2_k127_8159419_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000003021 121.0
HKD2_k127_8159419_3 4Fe-4S binding domain - - - 0.000000000000000000000000007485 111.0
HKD2_k127_8159419_4 Phosphoesterase, PA-phosphatase related K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000001591 116.0
HKD2_k127_8159617_0 Thiazole biosynthesis protein ThiG K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 406.0
HKD2_k127_8159617_1 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 406.0
HKD2_k127_8159617_2 Ppx/GppA phosphatase family K01524 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0040007,GO:0044237,GO:0044464,GO:0071944 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001259 289.0
HKD2_k127_8159617_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000206 229.0
HKD2_k127_8159617_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000002271 198.0
HKD2_k127_8159617_5 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000005777 141.0
HKD2_k127_8159617_6 YacP-like NYN domain K06962 - - 0.00000000000000000000000000004243 128.0
HKD2_k127_8159617_7 thiamine diphosphate biosynthetic process K03154 - - 0.0000000001614 70.0
HKD2_k127_8159617_8 PFAM Ig domain protein, group 2 domain protein - - - 0.00000001127 69.0
HKD2_k127_8169756_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 537.0
HKD2_k127_8169756_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 420.0
HKD2_k127_8169756_10 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000003508 203.0
HKD2_k127_8169756_11 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003672 196.0
HKD2_k127_8169756_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000006518 178.0
HKD2_k127_8169756_13 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000003007 169.0
HKD2_k127_8169756_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000007893 158.0
HKD2_k127_8169756_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000806 164.0
HKD2_k127_8169756_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000004632 140.0
HKD2_k127_8169756_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000006604 137.0
HKD2_k127_8169756_18 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003991 127.0
HKD2_k127_8169756_19 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002632 114.0
HKD2_k127_8169756_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 335.0
HKD2_k127_8169756_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000008838 103.0
HKD2_k127_8169756_21 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000003702 66.0
HKD2_k127_8169756_22 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001421 71.0
HKD2_k127_8169756_23 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000007406 66.0
HKD2_k127_8169756_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 293.0
HKD2_k127_8169756_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 296.0
HKD2_k127_8169756_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 286.0
HKD2_k127_8169756_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000008595 238.0
HKD2_k127_8169756_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001471 240.0
HKD2_k127_8169756_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002812 224.0
HKD2_k127_8169756_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004127 200.0
HKD2_k127_8183907_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K00344,K00966,K01840,K03431,K15778,K16881 - 1.6.5.5,2.7.7.13,5.4.2.10,5.4.2.2,5.4.2.8 0.0 1134.0
HKD2_k127_8183907_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.45e-248 778.0
HKD2_k127_8183907_10 cell cycle K05589,K12065,K13052 - - 0.00000000000002999 77.0
HKD2_k127_8183907_11 Putative regulatory protein - - - 0.00000000008004 63.0
HKD2_k127_8183907_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.998e-195 618.0
HKD2_k127_8183907_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009055,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0022900,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 494.0
HKD2_k127_8183907_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 407.0
HKD2_k127_8183907_5 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 375.0
HKD2_k127_8183907_6 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000003206 130.0
HKD2_k127_8183907_7 Malate/L-lactate dehydrogenase - - - 0.00000000000000000005683 93.0
HKD2_k127_8183907_8 VanZ like family - - - 0.0000000000000000004217 97.0
HKD2_k127_8183907_9 Ribbon-helix-helix protein, copG family - - - 0.00000000000000009904 81.0
HKD2_k127_8205953_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 503.0
HKD2_k127_8205953_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 316.0
HKD2_k127_8205953_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000005333 170.0
HKD2_k127_8205953_3 Histidine kinase - - - 0.0000002931 52.0
HKD2_k127_8258150_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 304.0
HKD2_k127_8258150_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000002955 112.0
HKD2_k127_8287126_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 7.345e-319 1000.0
HKD2_k127_8287126_1 Type II/IV secretion system protein K02454,K02652 - - 1.388e-274 869.0
HKD2_k127_8287126_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016787,GO:0016788,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.417e-218 693.0
HKD2_k127_8287126_3 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 532.0
HKD2_k127_8287126_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000004045 244.0
HKD2_k127_8287126_5 Type III restriction K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000007101 165.0
HKD2_k127_8388075_0 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 398.0
HKD2_k127_8388075_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 397.0
HKD2_k127_8388075_2 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000001036 202.0
HKD2_k127_8388075_3 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000002404 94.0
HKD2_k127_8388075_4 Phage integrase family - - - 0.000000001268 64.0
HKD2_k127_8443461_0 FAD linked oxidase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006738 269.0
HKD2_k127_8443461_1 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000001246 249.0
HKD2_k127_8444163_0 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 607.0
HKD2_k127_8444163_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000007142 101.0
HKD2_k127_8444163_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000002146 70.0
HKD2_k127_8444163_3 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00003664 51.0
HKD2_k127_8460568_0 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1028.0
HKD2_k127_8460568_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 524.0
HKD2_k127_8460568_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 382.0
HKD2_k127_8460568_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002691 257.0
HKD2_k127_8460568_4 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007364 239.0
HKD2_k127_8460568_5 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000002277 186.0
HKD2_k127_8460568_6 CAAX protease self-immunity - - - 0.000007965 58.0
HKD2_k127_852642_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 5.81e-225 711.0
HKD2_k127_852642_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 614.0
HKD2_k127_852642_10 ThiS family K03636 - - 0.00000000004264 67.0
HKD2_k127_852642_2 PFAM binding-protein-dependent transport systems inner membrane component K02025,K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 315.0
HKD2_k127_852642_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 300.0
HKD2_k127_852642_4 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009457 292.0
HKD2_k127_852642_5 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001865 278.0
HKD2_k127_852642_6 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004289 274.0
HKD2_k127_852642_7 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000001072 221.0
HKD2_k127_852642_8 transporter solute receptor, DctP family - - - 0.00000000000000000000000000000001531 134.0
HKD2_k127_852642_9 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000001485 72.0
HKD2_k127_856436_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K03336 - 3.7.1.22 9.825e-248 784.0
HKD2_k127_856436_1 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 509.0
HKD2_k127_856436_10 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000001224 229.0
HKD2_k127_856436_11 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000007116 220.0
HKD2_k127_856436_12 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000000009745 185.0
HKD2_k127_856436_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000002891 180.0
HKD2_k127_856436_14 Diguanylate cyclase - - - 0.0000000000000000000000000000000007966 142.0
HKD2_k127_856436_15 HIT domain K02503 - - 0.00000000000000000000000000000144 126.0
HKD2_k127_856436_16 - - - - 0.000000000000000000000000000002932 125.0
HKD2_k127_856436_17 - - - - 0.000000000005629 73.0
HKD2_k127_856436_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000001394 66.0
HKD2_k127_856436_19 Thioredoxin-like - - - 0.0000000007311 63.0
HKD2_k127_856436_2 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 445.0
HKD2_k127_856436_20 Thioredoxin-like - - - 0.000000006327 59.0
HKD2_k127_856436_21 COG1225 Peroxiredoxin - - - 0.00004955 49.0
HKD2_k127_856436_3 ABC transporter K17215 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 437.0
HKD2_k127_856436_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 417.0
HKD2_k127_856436_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 349.0
HKD2_k127_856436_6 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 317.0
HKD2_k127_856436_7 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 302.0
HKD2_k127_856436_8 QueT transporter K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005699 280.0
HKD2_k127_856436_9 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000002469 244.0
HKD2_k127_8581240_0 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 1.354e-205 652.0
HKD2_k127_8581240_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000005109 117.0
HKD2_k127_8649021_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 548.0
HKD2_k127_8649021_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 354.0
HKD2_k127_8649021_10 Belongs to the UPF0109 family K06960 GO:0008150,GO:0040007 - 0.000000000000000000000664 101.0
HKD2_k127_8649021_11 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000001395 101.0
HKD2_k127_8649021_12 SNARE associated Golgi protein - - - 0.000001888 50.0
HKD2_k127_8649021_2 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 325.0
HKD2_k127_8649021_3 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 285.0
HKD2_k127_8649021_4 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001528 275.0
HKD2_k127_8649021_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000003063 201.0
HKD2_k127_8649021_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000004251 168.0
HKD2_k127_8649021_7 Cupin - - - 0.000000000000000000000000000000004971 133.0
HKD2_k127_8649021_8 Nuclease-related domain K07460 - - 0.000000000000000000000000000002514 127.0
HKD2_k127_8649021_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000002793 119.0
HKD2_k127_8656027_0 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 434.0
HKD2_k127_8656027_1 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 422.0
HKD2_k127_8656027_10 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 254.0
HKD2_k127_8656027_11 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000009375 228.0
HKD2_k127_8656027_12 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000001446 218.0
HKD2_k127_8656027_13 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000004692 199.0
HKD2_k127_8656027_14 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000009825 181.0
HKD2_k127_8656027_15 Lysine exporter LysO - - - 0.000000000000000000000000000000000000000000000006615 178.0
HKD2_k127_8656027_16 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000003154 98.0
HKD2_k127_8656027_17 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000001134 64.0
HKD2_k127_8656027_18 Lysine exporter LysO - - - 0.000000274 55.0
HKD2_k127_8656027_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 419.0
HKD2_k127_8656027_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 391.0
HKD2_k127_8656027_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 369.0
HKD2_k127_8656027_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 341.0
HKD2_k127_8656027_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 315.0
HKD2_k127_8656027_7 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 316.0
HKD2_k127_8656027_8 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001241 301.0
HKD2_k127_8656027_9 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 263.0
HKD2_k127_8656465_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 458.0
HKD2_k127_8656465_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 387.0
HKD2_k127_8656465_2 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 383.0
HKD2_k127_8656465_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 374.0
HKD2_k127_8656465_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 292.0
HKD2_k127_8656465_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000527 230.0
HKD2_k127_8656465_6 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000003304 209.0
HKD2_k127_8656465_7 PFAM Pyruvate K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000103 166.0
HKD2_k127_8656465_8 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000001627 136.0
HKD2_k127_8656465_9 4 iron, 4 sulfur cluster binding K00176,K05524 - 1.2.7.3 0.000000000000006868 78.0
HKD2_k127_8660340_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 609.0
HKD2_k127_8660340_1 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 488.0
HKD2_k127_8660340_10 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000005892 258.0
HKD2_k127_8660340_11 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000002436 254.0
HKD2_k127_8660340_12 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
HKD2_k127_8660340_13 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000000000000000000003771 227.0
HKD2_k127_8660340_14 FCD - - - 0.00000000000000000000000000000000000000000000009115 179.0
HKD2_k127_8660340_15 VKc - - - 0.00000000000000002681 88.0
HKD2_k127_8660340_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001929 82.0
HKD2_k127_8660340_17 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000364 82.0
HKD2_k127_8660340_2 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 448.0
HKD2_k127_8660340_3 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 436.0
HKD2_k127_8660340_4 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 383.0
HKD2_k127_8660340_5 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 378.0
HKD2_k127_8660340_6 Zinc-binding dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 369.0
HKD2_k127_8660340_7 Transketolase, thiamine diphosphate binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 364.0
HKD2_k127_8660340_8 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 363.0
HKD2_k127_8660340_9 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 348.0
HKD2_k127_8798762_0 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 295.0
HKD2_k127_8798762_1 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000142 94.0
HKD2_k127_8820507_0 Belongs to the DegT DnrJ EryC1 family K16016 - 4.2.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 385.0
HKD2_k127_8820507_1 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 311.0
HKD2_k127_8820507_2 Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000001873 206.0
HKD2_k127_8820507_3 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000001694 175.0
HKD2_k127_8820507_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000001151 159.0
HKD2_k127_8820507_5 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000008015 85.0
HKD2_k127_8862596_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 355.0
HKD2_k127_8862596_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
HKD2_k127_8862596_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000859 191.0
HKD2_k127_8862596_3 tagaturonate epimerase - - - 0.000000000000000000000000000005043 138.0
HKD2_k127_8862596_4 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000004226 109.0
HKD2_k127_8862596_5 Putative transposase - - - 0.0000000000000000000001166 100.0
HKD2_k127_8862596_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00001884 48.0
HKD2_k127_8890573_0 Glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 520.0
HKD2_k127_8890573_1 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 495.0
HKD2_k127_8956885_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 344.0
HKD2_k127_8956885_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 339.0
HKD2_k127_8956885_10 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000001273 76.0
HKD2_k127_8956885_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 326.0
HKD2_k127_8956885_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 316.0
HKD2_k127_8956885_4 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 315.0
HKD2_k127_8956885_5 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001001 283.0
HKD2_k127_8956885_6 Fructose-1,6-bisphosphate aldolase, class II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000001192 201.0
HKD2_k127_8956885_7 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000006992 163.0
HKD2_k127_8956885_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000001374 166.0
HKD2_k127_8956885_9 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000001038 117.0
HKD2_k127_8959399_0 PFAM alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 6.266e-252 788.0
HKD2_k127_8959399_1 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 550.0
HKD2_k127_8959399_10 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000000000000000000008036 205.0
HKD2_k127_8959399_11 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000002051 205.0
HKD2_k127_8959399_12 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000008892 173.0
HKD2_k127_8959399_13 GntR family - - - 0.0000000000000000000000000000000000005362 152.0
HKD2_k127_8959399_14 haloacid dehalogenase-like hydrolase - - - 0.00000002056 62.0
HKD2_k127_8959399_15 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.0000002606 56.0
HKD2_k127_8959399_2 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 481.0
HKD2_k127_8959399_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 487.0
HKD2_k127_8959399_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 456.0
HKD2_k127_8959399_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 384.0
HKD2_k127_8959399_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 324.0
HKD2_k127_8959399_7 binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009893 252.0
HKD2_k127_8959399_8 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000001681 227.0
HKD2_k127_8959399_9 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000001987 226.0
HKD2_k127_8973772_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1474.0
HKD2_k127_8984100_0 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.0 1034.0
HKD2_k127_8984100_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007843 263.0
HKD2_k127_8984100_2 - - - - 0.0000000000000000000000000000000000000000000000007497 178.0
HKD2_k127_8984100_3 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000002769 133.0
HKD2_k127_8984100_4 Iron-sulfur cluster-binding domain K06871 - - 0.0000002489 60.0
HKD2_k127_9006391_0 Sulfatase K01130 - 3.1.6.1 1.187e-279 866.0
HKD2_k127_9035296_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 589.0
HKD2_k127_9035296_1 Tetratricopeptide repeat K11935 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 544.0
HKD2_k127_9035296_10 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 342.0
HKD2_k127_9035296_11 ABC transporter permease K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 328.0
HKD2_k127_9035296_12 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 326.0
HKD2_k127_9035296_13 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004433 280.0
HKD2_k127_9035296_14 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005473 278.0
HKD2_k127_9035296_15 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006704 268.0
HKD2_k127_9035296_16 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001099 253.0
HKD2_k127_9035296_17 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001212 253.0
HKD2_k127_9035296_18 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000754 236.0
HKD2_k127_9035296_19 CarD-like/TRCF domain K07736 GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0040007,GO:0042594,GO:0044419,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
HKD2_k127_9035296_2 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 524.0
HKD2_k127_9035296_20 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000001078 213.0
HKD2_k127_9035296_21 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001127 209.0
HKD2_k127_9035296_22 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000093 205.0
HKD2_k127_9035296_23 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000007808 205.0
HKD2_k127_9035296_24 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000001785 200.0
HKD2_k127_9035296_25 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000005742 189.0
HKD2_k127_9035296_26 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000307 185.0
HKD2_k127_9035296_27 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.000000000000000000000000000000000005769 155.0
HKD2_k127_9035296_28 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000272 135.0
HKD2_k127_9035296_29 Thioesterase superfamily - - - 0.00000000000000000000000000000003469 131.0
HKD2_k127_9035296_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 492.0
HKD2_k127_9035296_30 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003961 118.0
HKD2_k127_9035296_31 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000000000965 109.0
HKD2_k127_9035296_32 Binds together with S18 to 16S ribosomal RNA K01754,K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 4.3.1.19 0.0000000000000000000000004827 108.0
HKD2_k127_9035296_33 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000003134 85.0
HKD2_k127_9035296_34 - - - - 0.00003364 46.0
HKD2_k127_9035296_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 456.0
HKD2_k127_9035296_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 444.0
HKD2_k127_9035296_6 Family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 429.0
HKD2_k127_9035296_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 415.0
HKD2_k127_9035296_8 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 389.0
HKD2_k127_9035296_9 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 346.0
HKD2_k127_9045409_1 heat shock protein DnaJ K05516 - - 0.000000000000000000002948 101.0
HKD2_k127_9050783_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1025.0
HKD2_k127_9050783_1 Phosphoglucose isomerase K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 1.595e-300 929.0
HKD2_k127_9050783_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000008953 211.0
HKD2_k127_9050783_11 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000001652 200.0
HKD2_k127_9050783_12 Phosphoglycerate mutase family - - - 0.000000005053 57.0
HKD2_k127_9050783_13 - - - - 0.0003476 48.0
HKD2_k127_9050783_2 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 1.22e-278 865.0
HKD2_k127_9050783_3 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 559.0
HKD2_k127_9050783_4 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 531.0
HKD2_k127_9050783_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008705 376.0
HKD2_k127_9050783_6 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 327.0
HKD2_k127_9050783_7 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006065 281.0
HKD2_k127_9050783_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000005868 250.0
HKD2_k127_9050783_9 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000000000000000000000008936 222.0
HKD2_k127_9076201_0 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000293 205.0
HKD2_k127_9076201_1 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002775 181.0
HKD2_k127_9076201_2 4Fe-4S binding domain K14091 - - 0.0000000000000000000000000000000000000000000000003077 186.0
HKD2_k127_9076201_3 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000141 169.0
HKD2_k127_9076201_4 PFAM SpoVT AbrB K07172 - - 0.000000000000000000000000002579 113.0
HKD2_k127_9076201_5 spore germination K00442,K08315 - 3.4.23.51 0.000000000000000000000001486 111.0
HKD2_k127_9076201_6 Methyltransferase type 11 - - - 0.00000005289 55.0
HKD2_k127_9076807_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.324e-216 685.0
HKD2_k127_9076807_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.939e-212 671.0
HKD2_k127_9076807_2 PFAM Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 340.0
HKD2_k127_9076807_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 337.0
HKD2_k127_9076807_4 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 301.0
HKD2_k127_9076807_5 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004674 269.0
HKD2_k127_9076807_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001846 235.0
HKD2_k127_9076807_7 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000003403 230.0
HKD2_k127_9076807_8 Cytochrome C oxidase, cbb3-type, subunit III K00368 - 1.7.2.1 0.00001434 48.0
HKD2_k127_9092623_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 2.548e-237 751.0
HKD2_k127_9092623_1 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 6.275e-218 695.0
HKD2_k127_9092623_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000006305 244.0
HKD2_k127_9092623_11 Cell shape-determining protein MreC K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0030428,GO:0031224,GO:0031226,GO:0042546,GO:0043621,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944,GO:0071963 - 0.0000000000000000000000000000000000000000000000000000000000000000003736 240.0
HKD2_k127_9092623_12 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000004163 229.0
HKD2_k127_9092623_13 - - - - 0.0000000000000000000000000000000000000000000000000000009547 198.0
HKD2_k127_9092623_14 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.00000000000000000000000000000000000000000000000000002104 197.0
HKD2_k127_9092623_15 peptidyl-prolyl cis-trans isomerase activity K03770,K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000000000001835 195.0
HKD2_k127_9092623_16 - - - - 0.00000000000000000000000000000000002539 141.0
HKD2_k127_9092623_18 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000000000001432 115.0
HKD2_k127_9092623_19 cheY-homologous receiver domain K11443 - - 0.00000000000000000001479 98.0
HKD2_k127_9092623_2 MreB/Mbl protein K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 595.0
HKD2_k127_9092623_3 TOBE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 440.0
HKD2_k127_9092623_4 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 405.0
HKD2_k127_9092623_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 392.0
HKD2_k127_9092623_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 387.0
HKD2_k127_9092623_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 335.0
HKD2_k127_9092623_8 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 316.0
HKD2_k127_9092623_9 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001795 272.0
HKD2_k127_9101339_0 Glycogen debranching enzyme - - - 7.543e-240 744.0
HKD2_k127_9101339_1 PFAM RNA polymerase sigma factor 54, interaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 556.0
HKD2_k127_9101339_2 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 310.0
HKD2_k127_9101339_3 - - - - 0.00000000000000000000000000000000000000000000000005489 192.0
HKD2_k127_9101339_4 - - - - 0.00000000000000000000000001199 111.0
HKD2_k127_9101339_5 Antibiotic biosynthesis monooxygenase - - - 0.000000003482 64.0
HKD2_k127_9179371_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1218.0
HKD2_k127_9179371_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 464.0
HKD2_k127_9179371_2 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 374.0
HKD2_k127_9179371_3 daunorubicin resistance ABC transporter membrane protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
HKD2_k127_9179371_4 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000002464 147.0
HKD2_k127_9179900_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067,K18118 - 2.8.3.18,3.1.2.1 1.226e-255 796.0
HKD2_k127_9179900_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.966e-209 657.0
HKD2_k127_9179900_2 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 601.0
HKD2_k127_9179900_3 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 520.0
HKD2_k127_9179900_4 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 310.0
HKD2_k127_9179900_5 Fibronectin type 3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003838 267.0
HKD2_k127_9179900_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000005053 207.0
HKD2_k127_9179900_7 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000005605 104.0
HKD2_k127_9179900_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000003 73.0
HKD2_k127_9213899_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1165.0
HKD2_k127_9213899_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.234e-311 976.0
HKD2_k127_9213899_10 PFAM Na Picotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 421.0
HKD2_k127_9213899_11 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 374.0
HKD2_k127_9213899_12 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 363.0
HKD2_k127_9213899_13 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
HKD2_k127_9213899_14 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 286.0
HKD2_k127_9213899_15 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008322 289.0
HKD2_k127_9213899_16 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004544 274.0
HKD2_k127_9213899_17 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000009923 260.0
HKD2_k127_9213899_18 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000081 273.0
HKD2_k127_9213899_19 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000002074 250.0
HKD2_k127_9213899_2 thiamine pyrophosphate protein TPP binding domain protein K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 4.057e-279 868.0
HKD2_k127_9213899_20 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000001163 214.0
HKD2_k127_9213899_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000006101 216.0
HKD2_k127_9213899_22 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000006948 209.0
HKD2_k127_9213899_23 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25 0.00000000000000000000000000000000000000000000000000000002945 207.0
HKD2_k127_9213899_24 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000002837 196.0
HKD2_k127_9213899_25 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000004025 202.0
HKD2_k127_9213899_26 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000001545 181.0
HKD2_k127_9213899_27 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530,K05788 - - 0.0000000000000000000000000000000000004086 141.0
HKD2_k127_9213899_28 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000004282 151.0
HKD2_k127_9213899_29 RecX family K03565 - - 0.0000000000000000002549 94.0
HKD2_k127_9213899_3 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 4.378e-272 850.0
HKD2_k127_9213899_30 family 5 K15580 - - 0.0000000000000001453 92.0
HKD2_k127_9213899_31 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000002137 92.0
HKD2_k127_9213899_32 sequence-specific DNA binding - - - 0.0000000000001215 82.0
HKD2_k127_9213899_33 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000002171 68.0
HKD2_k127_9213899_35 Domain of unknown function (DUF4845) - - - 0.000308 49.0
HKD2_k127_9213899_36 Leucine-rich repeats, typical (most populated) subfamily K19613 - - 0.0003371 47.0
HKD2_k127_9213899_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.475e-247 772.0
HKD2_k127_9213899_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004455,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 541.0
HKD2_k127_9213899_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 531.0
HKD2_k127_9213899_7 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 525.0
HKD2_k127_9213899_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 473.0
HKD2_k127_9213899_9 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 436.0
HKD2_k127_9216964_0 methyltransferase activity - - - 0.00000000000006796 80.0
HKD2_k127_9216964_1 Phospholipid methyltransferase - - - 0.00000000004905 70.0
HKD2_k127_9217428_0 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000002657 187.0
HKD2_k127_9217428_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000004868 95.0
HKD2_k127_9217428_3 EamA-like transporter family - - - 0.00000000000000007389 84.0
HKD2_k127_9217428_5 EF hand - - - 0.0008996 43.0
HKD2_k127_9228551_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0 1180.0
HKD2_k127_9228551_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1008.0
HKD2_k127_9228551_10 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000007504 191.0
HKD2_k127_9228551_11 amino acid - - - 0.0000000000000000000000000000000000000005809 152.0
HKD2_k127_9228551_12 - - - - 0.000000000000000000006024 96.0
HKD2_k127_9228551_13 Domain of unknown function (DUF4118) K07646 - 2.7.13.3 0.00000000006088 72.0
HKD2_k127_9228551_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 1.001e-281 877.0
HKD2_k127_9228551_3 Amino acid permease - - - 1.636e-195 626.0
HKD2_k127_9228551_4 TIGRFAM Potassium uptake protein TrkH K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 511.0
HKD2_k127_9228551_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 369.0
HKD2_k127_9228551_6 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 361.0
HKD2_k127_9228551_7 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001797 276.0
HKD2_k127_9228551_8 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
HKD2_k127_9228551_9 TrkA-N domain K03499,K10716 - - 0.0000000000000000000000000000000000000000000000000000001184 202.0
HKD2_k127_9250556_0 helicase superfamily c-terminal domain K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 3.085e-295 927.0
HKD2_k127_9250556_1 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 595.0
HKD2_k127_9250556_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 344.0
HKD2_k127_9250556_11 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000003295 107.0
HKD2_k127_9250556_12 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000004999 92.0
HKD2_k127_9250556_13 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000006061 88.0
HKD2_k127_9250556_14 PFAM nuclease (SNase domain protein) - - - 0.000000000000002133 84.0
HKD2_k127_9250556_15 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.00008782 48.0
HKD2_k127_9250556_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 561.0
HKD2_k127_9250556_3 PFAM aminotransferase class-III K01845,K21585 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006083,GO:0006091,GO:0006113,GO:0006520,GO:0006553,GO:0006554,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016740,GO:0016769,GO:0016853,GO:0016866,GO:0016869,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019475,GO:0019477,GO:0019665,GO:0019666,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0040007,GO:0042168,GO:0042286,GO:0042440,GO:0042737,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044464,GO:0046148,GO:0046395,GO:0046440,GO:0046483,GO:0046501,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 2.6.1.111,5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 555.0
HKD2_k127_9250556_4 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 512.0
HKD2_k127_9250556_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 531.0
HKD2_k127_9250556_6 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 497.0
HKD2_k127_9250556_7 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 456.0
HKD2_k127_9250556_8 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0097159,GO:1901265,GO:1901363 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 383.0
HKD2_k127_9250556_9 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 351.0
HKD2_k127_9253327_0 carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 527.0
HKD2_k127_9253327_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000005321 179.0
HKD2_k127_9253327_2 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000127 96.0
HKD2_k127_9306270_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.916e-203 640.0
HKD2_k127_9306270_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05559,K05565 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 622.0
HKD2_k127_9306270_10 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000002261 132.0
HKD2_k127_9306270_11 - - - - 0.00000000000000000000000002718 112.0
HKD2_k127_9306270_12 4Fe-4S binding domain - - - 0.00000000000000000000005491 105.0
HKD2_k127_9306270_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000268 90.0
HKD2_k127_9306270_14 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000004465 81.0
HKD2_k127_9306270_2 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 471.0
HKD2_k127_9306270_3 Malate/L-lactate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 374.0
HKD2_k127_9306270_4 ATP synthesis coupled electron transport K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 332.0
HKD2_k127_9306270_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 318.0
HKD2_k127_9306270_6 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006384 266.0
HKD2_k127_9306270_7 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000009115 264.0
HKD2_k127_9306270_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000002623 205.0
HKD2_k127_9306270_9 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000006537 196.0
HKD2_k127_9325622_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.852e-221 694.0
HKD2_k127_9325622_1 thiamine transport K02011 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 601.0
HKD2_k127_9325622_10 mannose-6-phosphate isomerase K01809 - 5.3.1.8 0.000000000000000000000000000000000001147 142.0
HKD2_k127_9325622_11 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.0000000000000000000000000002851 123.0
HKD2_k127_9325622_12 Ferredoxin - - - 0.000000000000000000001975 100.0
HKD2_k127_9325622_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 488.0
HKD2_k127_9325622_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 438.0
HKD2_k127_9325622_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007055 403.0
HKD2_k127_9325622_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 392.0
HKD2_k127_9325622_6 TOBE domain K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 379.0
HKD2_k127_9325622_7 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 355.0
HKD2_k127_9325622_8 Oxidoreductase family, NAD-binding Rossmann fold K18106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 353.0
HKD2_k127_9325622_9 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 315.0
HKD2_k127_9327319_0 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 307.0
HKD2_k127_9327319_1 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
HKD2_k127_9327319_2 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000001195 226.0
HKD2_k127_9327319_3 Methyltransferase MtaA K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000472 226.0
HKD2_k127_9327319_4 with different specificities (related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000000003338 218.0
HKD2_k127_9327319_5 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000002896 196.0
HKD2_k127_9327319_6 Aldolase/RraA - - - 0.00000000000000000000000000000000000000006153 159.0
HKD2_k127_9327319_7 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000001 157.0
HKD2_k127_9327319_8 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000008888 149.0
HKD2_k127_9327319_9 PFAM KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000001299 75.0
HKD2_k127_9338314_0 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000001199 199.0
HKD2_k127_9338314_1 methyltransferase - - - 0.0000000000000000000000000000000000192 145.0
HKD2_k127_9344451_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0 1216.0
HKD2_k127_9344451_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 606.0
HKD2_k127_9344451_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 598.0
HKD2_k127_9344451_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 421.0
HKD2_k127_9344451_4 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002714 264.0
HKD2_k127_9344451_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003718 261.0
HKD2_k127_9344451_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000002195 189.0
HKD2_k127_9344451_7 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000004864 140.0
HKD2_k127_9344451_8 Protein of unknown function (DUF1559) - - - 0.00005007 50.0
HKD2_k127_9352084_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 8.771e-238 752.0
HKD2_k127_9352084_1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 359.0
HKD2_k127_9352084_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.0000000000000000000000000000000000000000000000000000000000000000000002016 243.0
HKD2_k127_9352084_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
HKD2_k127_9352084_4 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000009405 156.0
HKD2_k127_9352084_5 TPM domain K06872 - - 0.0000000000000000000000000000000000641 147.0
HKD2_k127_9352084_6 Protein of unknown function (DUF2847) - - - 0.00000000000002294 75.0
HKD2_k127_9352084_7 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000005958 74.0
HKD2_k127_9369627_0 FAD linked oxidase domain protein - - - 0.0 1030.0
HKD2_k127_9369627_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 614.0
HKD2_k127_9369627_10 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 364.0
HKD2_k127_9369627_11 Peptidase family M23 K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 348.0
HKD2_k127_9369627_12 COG3959 Transketolase, N-terminal subunit K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 338.0
HKD2_k127_9369627_13 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 327.0
HKD2_k127_9369627_14 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0000910,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006928,GO:0007049,GO:0007154,GO:0007165,GO:0007166,GO:0008150,GO:0008356,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0016020,GO:0016021,GO:0016043,GO:0019221,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0023052,GO:0030312,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0032506,GO:0034097,GO:0040007,GO:0040011,GO:0042173,GO:0042221,GO:0043207,GO:0043937,GO:0043938,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070098,GO:0070297,GO:0070887,GO:0071310,GO:0071345,GO:0071840,GO:0071944,GO:0071976,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 316.0
HKD2_k127_9369627_15 ATPases associated with a variety of cellular activities K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 304.0
HKD2_k127_9369627_16 - K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 304.0
HKD2_k127_9369627_17 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004895 263.0
HKD2_k127_9369627_18 Xylose isomerase-like TIM barrel K00010,K03335 - 1.1.1.18,1.1.1.369,4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000003726 270.0
HKD2_k127_9369627_19 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001972 263.0
HKD2_k127_9369627_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 565.0
HKD2_k127_9369627_20 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000375 224.0
HKD2_k127_9369627_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000001366 186.0
HKD2_k127_9369627_22 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000001211 178.0
HKD2_k127_9369627_23 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000001384 173.0
HKD2_k127_9369627_24 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000627 153.0
HKD2_k127_9369627_25 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000255 132.0
HKD2_k127_9369627_26 Putative zinc-finger - - - 0.00000000000000000000000000002948 129.0
HKD2_k127_9369627_27 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000009743 111.0
HKD2_k127_9369627_28 - - - - 0.00000000000000000000000227 104.0
HKD2_k127_9369627_29 Transporter, major facilitator family protein K08161 - - 0.0000000000000008632 90.0
HKD2_k127_9369627_3 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 527.0
HKD2_k127_9369627_4 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 512.0
HKD2_k127_9369627_5 glucuronate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 479.0
HKD2_k127_9369627_6 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 447.0
HKD2_k127_9369627_7 Insertion element 4 transposase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 416.0
HKD2_k127_9369627_8 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 406.0
HKD2_k127_9369627_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 385.0
HKD2_k127_9371654_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 569.0
HKD2_k127_9371654_1 PFAM FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 521.0
HKD2_k127_9371654_2 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 409.0
HKD2_k127_9371654_3 COG1233 Phytoene dehydrogenase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 378.0
HKD2_k127_9371654_4 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 352.0
HKD2_k127_9371654_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003307 283.0
HKD2_k127_9371654_6 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000158 228.0
HKD2_k127_9371654_7 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000000000002618 170.0
HKD2_k127_9371654_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03574 - 3.6.1.55 0.000000000000000000000000000000001545 139.0
HKD2_k127_9371654_9 FAD linked oxidases, C-terminal domain K11472 - - 0.0000001192 57.0
HKD2_k127_9391577_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 569.0
HKD2_k127_9391577_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 535.0
HKD2_k127_9391577_10 Phosphoribosyl-AMP cyclohydrolase K01496,K01497,K01523,K01814,K11755 GO:0000105,GO:0000287,GO:0003674,GO:0003824,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043167,GO:0043169,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052803,GO:0071704,GO:0071944,GO:0075136,GO:0075139,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000001021 261.0
HKD2_k127_9391577_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002556 248.0
HKD2_k127_9391577_12 Imidazoleglycerol-phosphate dehydratase K00013,K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,2.6.1.9,3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001998 240.0
HKD2_k127_9391577_13 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000007638 225.0
HKD2_k127_9391577_14 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000006009 220.0
HKD2_k127_9391577_15 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000003032 179.0
HKD2_k127_9391577_16 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.00000000000000000000000001647 112.0
HKD2_k127_9391577_17 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000005434 94.0
HKD2_k127_9391577_18 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K02887,K03628 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000006312 57.0
HKD2_k127_9391577_19 - - - - 0.000006727 48.0
HKD2_k127_9391577_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 484.0
HKD2_k127_9391577_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 462.0
HKD2_k127_9391577_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 462.0
HKD2_k127_9391577_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500,K11755 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 380.0
HKD2_k127_9391577_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 362.0
HKD2_k127_9391577_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001575 297.0
HKD2_k127_9391577_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
HKD2_k127_9391577_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001404 277.0
HKD2_k127_9393214_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000995 270.0
HKD2_k127_9393214_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000001723 62.0
HKD2_k127_9395840_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 443.0
HKD2_k127_9395840_1 Transglycosylase SLT domain K07114,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 428.0
HKD2_k127_9395840_2 Phosphomethylpyrimidine kinase K00868,K00941,K03147,K21219 GO:0008150,GO:0040007 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7,4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009668 273.0
HKD2_k127_9395840_3 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000003378 140.0
HKD2_k127_9395840_4 - - - - 0.00000004023 57.0
HKD2_k127_9410334_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 475.0
HKD2_k127_9410334_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 378.0
HKD2_k127_9410334_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000009962 198.0
HKD2_k127_9410334_3 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000003867 143.0
HKD2_k127_9417089_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000003091 141.0
HKD2_k127_9417089_1 PFAM Xylose isomerase - - - 0.0000000000000000000000000000001303 134.0
HKD2_k127_9417089_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000005478 59.0
HKD2_k127_9440346_0 isochorismatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 481.0
HKD2_k127_9440346_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000022 265.0
HKD2_k127_9440346_2 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000004936 158.0
HKD2_k127_9440346_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000001873 111.0
HKD2_k127_9440346_4 Serine threonine protein kinase K12132 - 2.7.11.1 0.000001141 55.0
HKD2_k127_9497215_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1324.0
HKD2_k127_9497215_1 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 438.0
HKD2_k127_9497215_10 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. - - - 0.0003772 48.0
HKD2_k127_9497215_2 Dihydroxyacetone kinase K05878 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 378.0
HKD2_k127_9497215_3 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 396.0
HKD2_k127_9497215_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 358.0
HKD2_k127_9497215_5 Belongs to the DapA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 347.0
HKD2_k127_9497215_6 Dak2 K05879 - 2.7.1.121 0.000000000000000000000000000000000000000000622 175.0
HKD2_k127_9497215_7 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000002713 162.0
HKD2_k127_9497215_8 - - - - 0.0000000000000000000000000000000001078 137.0
HKD2_k127_9497215_9 Chromate transporter K07240 - - 0.0000000000000000000000000000002132 130.0
HKD2_k127_951104_0 DNA polymerase X family K02347,K04477 - - 5.338e-225 711.0
HKD2_k127_951104_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 567.0
HKD2_k127_951104_10 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000001409 169.0
HKD2_k127_951104_11 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000167 161.0
HKD2_k127_951104_12 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000000000000000000000000002069 152.0
HKD2_k127_951104_13 Glycoprotease family - - - 0.000000000000000000000000000000000005978 145.0
HKD2_k127_951104_14 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000007104 122.0
HKD2_k127_951104_15 Protein of unknown function (DUF721) - - - 0.000000000001737 74.0
HKD2_k127_951104_16 SMART ATP-binding region ATPase domain protein - - - 0.000000000005577 72.0
HKD2_k127_951104_17 DUF72 domain containing protein - - - 0.0004207 45.0
HKD2_k127_951104_2 Acetamidase/Formamidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 552.0
HKD2_k127_951104_3 histidine kinase, HAMP K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 570.0
HKD2_k127_951104_4 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 372.0
HKD2_k127_951104_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108,4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 368.0
HKD2_k127_951104_6 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 327.0
HKD2_k127_951104_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 320.0
HKD2_k127_951104_8 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000008584 230.0
HKD2_k127_951104_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000004981 230.0
HKD2_k127_9532032_0 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 428.0
HKD2_k127_9532032_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000003337 89.0
HKD2_k127_9532032_3 - - - - 0.0005583 51.0
HKD2_k127_9533811_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 631.0
HKD2_k127_9533811_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 539.0
HKD2_k127_9533811_10 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 295.0
HKD2_k127_9533811_11 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000001356 183.0
HKD2_k127_9533811_12 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000004409 93.0
HKD2_k127_9533811_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000001428 77.0
HKD2_k127_9533811_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 520.0
HKD2_k127_9533811_3 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 392.0
HKD2_k127_9533811_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 376.0
HKD2_k127_9533811_5 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 379.0
HKD2_k127_9533811_6 Dihydroorotate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 365.0
HKD2_k127_9533811_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 319.0
HKD2_k127_9533811_8 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 318.0
HKD2_k127_9533811_9 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 314.0
HKD2_k127_9573269_0 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 599.0
HKD2_k127_9573269_1 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 507.0
HKD2_k127_9573269_2 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 395.0
HKD2_k127_9573269_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 348.0
HKD2_k127_9573269_4 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 346.0
HKD2_k127_9573269_5 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 343.0
HKD2_k127_9573269_6 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 346.0
HKD2_k127_9573269_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000004781 213.0
HKD2_k127_9573269_8 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000000000000000000000008367 183.0
HKD2_k127_9640082_0 Threonine synthase K01733 - 4.2.3.1 6.039e-292 906.0
HKD2_k127_9640082_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 439.0
HKD2_k127_9640082_10 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000198 250.0
HKD2_k127_9640082_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
HKD2_k127_9640082_12 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000000000000004722 241.0
HKD2_k127_9640082_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001239 186.0
HKD2_k127_9640082_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000009888 142.0
HKD2_k127_9640082_15 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000003907 145.0
HKD2_k127_9640082_16 Psort location Cytoplasmic, score - - - 0.0000000000000000000006257 108.0
HKD2_k127_9640082_17 Domain of unknown function (DUF1844) - - - 0.000000000000000007272 87.0
HKD2_k127_9640082_18 - - - - 0.00000002521 56.0
HKD2_k127_9640082_19 peptidyl-tyrosine sulfation K00525,K01768 - 1.17.4.1,4.6.1.1 0.00000003341 65.0
HKD2_k127_9640082_2 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 413.0
HKD2_k127_9640082_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 409.0
HKD2_k127_9640082_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 367.0
HKD2_k127_9640082_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 335.0
HKD2_k127_9640082_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 321.0
HKD2_k127_9640082_7 Nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000091 282.0
HKD2_k127_9640082_8 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001204 274.0
HKD2_k127_9640082_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002507 254.0
HKD2_k127_9663292_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 409.0
HKD2_k127_9663292_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 362.0
HKD2_k127_9663292_2 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 311.0
HKD2_k127_9663292_3 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814,K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002434 272.0
HKD2_k127_9663292_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008838 269.0
HKD2_k127_9663292_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000001886 106.0
HKD2_k127_9707002_0 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 390.0
HKD2_k127_9707002_1 - - - - 0.0000001062 60.0
HKD2_k127_9732359_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 343.0
HKD2_k127_9732359_1 PFAM Acyl-CoA dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 299.0
HKD2_k127_9865954_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000007547 143.0
HKD2_k127_9865954_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000003366 94.0
HKD2_k127_9865954_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000001721 80.0
HKD2_k127_9865954_3 Diguanylate cyclase - - - 0.0000000000002041 78.0
HKD2_k127_990498_0 Belongs to the peptidase M16 family K07263 - - 0.0 1017.0
HKD2_k127_990498_1 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 1.297e-280 876.0
HKD2_k127_990498_10 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002597 280.0
HKD2_k127_990498_11 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
HKD2_k127_990498_13 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000593 218.0
HKD2_k127_990498_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330,K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000000000000501 188.0
HKD2_k127_990498_15 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000005238 197.0
HKD2_k127_990498_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000005995 188.0
HKD2_k127_990498_17 - - - - 0.00000000000000000000000000000000000000000000002767 177.0
HKD2_k127_990498_18 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000000000000000000000000000000000001345 170.0
HKD2_k127_990498_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000002301 160.0
HKD2_k127_990498_2 Hydantoinase/oxoprolinase - - - 3.075e-262 826.0
HKD2_k127_990498_20 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000003338 76.0
HKD2_k127_990498_21 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000001773 74.0
HKD2_k127_990498_22 ligase activity - - - 0.00001571 55.0
HKD2_k127_990498_3 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.694e-245 769.0
HKD2_k127_990498_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 602.0
HKD2_k127_990498_5 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 522.0
HKD2_k127_990498_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 550.0
HKD2_k127_990498_7 C4-dicarboxylate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 472.0
HKD2_k127_990498_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 413.0
HKD2_k127_990498_9 homoserine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 409.0
HKD2_k127_9952457_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1050.0
HKD2_k127_9952457_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K12266 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 580.0
HKD2_k127_9952457_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
HKD2_k127_9952457_3 Cupin - - - 0.000000000000005883 78.0
HKD2_k127_9960848_0 ABC-type Fe3 transport system permease component K02011 - - 2.332e-210 666.0
HKD2_k127_9960848_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 414.0
HKD2_k127_9960848_2 PFAM EamA-like transporter family - - - 0.0000000002014 71.0
HKD2_k127_9995635_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.069e-273 849.0
HKD2_k127_9995635_1 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
HKD2_k127_9995635_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0005502 47.0
HKD2_k127_9995635_2 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000009437 206.0
HKD2_k127_9995635_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000003717 166.0
HKD2_k127_9995635_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000004277 154.0
HKD2_k127_9995635_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000016 153.0
HKD2_k127_9995635_6 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000116 122.0
HKD2_k127_9995635_7 PFAM Response regulator receiver domain - - - 0.00000000000000000000006577 105.0
HKD2_k127_9995635_8 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.000000000000000000004939 96.0
HKD2_k127_9995635_9 SPW repeat - - - 0.00002824 51.0