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Overview

ID MAG01776
Name HKD2_bin.16
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family UBA4823
Genus FEB-25
Species
Assembly information
Completeness (%) 75.98
Contamination (%) 4.08
GC content (%) 50.0
N50 (bp) 14,458
Genome size (bp) 3,798,839

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3250

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10104601_0 involved in signal transduction (via phosphorylation) involved in transcriptional regulatory mechanism and in the regulation of secondary metabolites catalytic activity ATP a protein ADP a phosphoprotein K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 394.0
HKD2_k127_10104601_1 oxidoreductase activity - - - 0.000000000000000000008362 110.0
HKD2_k127_10104601_2 endopeptidase activity - - - 0.0000000000000000139 100.0
HKD2_k127_10104601_3 Subtilase family - - - 0.0000000000008199 84.0
HKD2_k127_10133181_0 Inner membrane component of T3SS, cytoplasmic domain - - - 8.025e-201 661.0
HKD2_k127_10133181_1 PFAM Alpha amylase, catalytic K01176,K01208 GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 496.0
HKD2_k127_10133181_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001848 279.0
HKD2_k127_10133181_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000009465 185.0
HKD2_k127_10133181_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000002428 174.0
HKD2_k127_10133181_6 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000005997 92.0
HKD2_k127_10133181_7 lactoylglutathione lyase activity - - - 0.0000000001763 67.0
HKD2_k127_10179965_0 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 482.0
HKD2_k127_10179965_1 SERine Proteinase INhibitors K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 318.0
HKD2_k127_10179965_2 COGs COG0674 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000005342 88.0
HKD2_k127_1031770_0 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000057 164.0
HKD2_k127_1040278_0 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 548.0
HKD2_k127_1040278_1 Aminotransferase class-V K00830,K03430 - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 434.0
HKD2_k127_1040278_2 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 423.0
HKD2_k127_1040278_3 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002989 260.0
HKD2_k127_1040278_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000004776 153.0
HKD2_k127_1040278_5 Redoxin - - - 0.0000000000005695 70.0
HKD2_k127_1040278_6 Protein of unknown function (DUF2892) - - - 0.000000000001725 71.0
HKD2_k127_1040278_7 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000178 66.0
HKD2_k127_1040278_8 - - - - 0.00000002172 62.0
HKD2_k127_1040278_9 Regulatory protein, FmdB family - - - 0.00000002713 57.0
HKD2_k127_104370_0 PFAM multicopper oxidase type 2 - - - 4.975e-275 866.0
HKD2_k127_104370_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 9.367e-210 669.0
HKD2_k127_104370_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.000000008828 63.0
HKD2_k127_104370_12 PFAM GCN5-related N-acetyltransferase - - - 0.0001541 48.0
HKD2_k127_104370_2 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 538.0
HKD2_k127_104370_3 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 373.0
HKD2_k127_104370_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000113 280.0
HKD2_k127_104370_5 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000735 233.0
HKD2_k127_104370_6 peptidoglycan turnover - - - 0.000000000000000000000000000000000000000000000000000001106 209.0
HKD2_k127_104370_7 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000004192 190.0
HKD2_k127_104370_8 regulatory protein, arsR - - - 0.00000000000000000000000000000000000004387 149.0
HKD2_k127_104370_9 pathogenesis K01179,K07004 - 3.2.1.4 0.0000000000000000000000000000408 134.0
HKD2_k127_1071757_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 8.214e-252 788.0
HKD2_k127_1071757_1 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 2.246e-204 641.0
HKD2_k127_1071757_10 PFAM Phage tail collar - - - 0.000000000000000000000000000000000000000000000000000000000000001696 222.0
HKD2_k127_1071757_12 Transcriptional regulator IclR K13641 - - 0.000000000000000000000000000000000000000000000000000001527 202.0
HKD2_k127_1071757_13 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000002566 145.0
HKD2_k127_1071757_14 domain, Protein - - - 0.00000000000000000000000001746 126.0
HKD2_k127_1071757_15 YacP-like NYN domain K06962 - - 0.00000000000000000000004926 105.0
HKD2_k127_1071757_16 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000002549 72.0
HKD2_k127_1071757_17 - - - - 0.0000000000002695 73.0
HKD2_k127_1071757_18 alginic acid biosynthetic process K13735,K21449 - - 0.0007832 52.0
HKD2_k127_1071757_2 ABC transporter K10441,K10562 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 515.0
HKD2_k127_1071757_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 504.0
HKD2_k127_1071757_4 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 492.0
HKD2_k127_1071757_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 424.0
HKD2_k127_1071757_6 Branched-chain amino acid transport system / permease component K02057,K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 323.0
HKD2_k127_1071757_7 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 322.0
HKD2_k127_1071757_8 PFAM Phage tail collar - - - 0.000000000000000000000000000000000000000000000000000000000000000000004146 238.0
HKD2_k127_1071757_9 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004064 226.0
HKD2_k127_1181381_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 3.511e-249 800.0
HKD2_k127_1181381_1 SMART AAA ATPase - - - 3.478e-222 694.0
HKD2_k127_1181381_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 334.0
HKD2_k127_1181381_11 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 313.0
HKD2_k127_1181381_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
HKD2_k127_1181381_13 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003271 247.0
HKD2_k127_1181381_14 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
HKD2_k127_1181381_15 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
HKD2_k127_1181381_16 Acyl CoA acetate 3-ketoacid CoA K01040 - 2.8.3.12 0.0000000000000000000000000000000000001402 151.0
HKD2_k127_1181381_17 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000006658 121.0
HKD2_k127_1181381_19 Putative membrane peptidase family (DUF2324) - - - 0.0000000000000000001249 92.0
HKD2_k127_1181381_2 His Kinase A (phosphoacceptor) domain - - - 3.171e-219 691.0
HKD2_k127_1181381_20 PBP superfamily domain K02040 - - 0.00004603 55.0
HKD2_k127_1181381_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 584.0
HKD2_k127_1181381_4 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 553.0
HKD2_k127_1181381_5 Serine threonine protein kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 474.0
HKD2_k127_1181381_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 455.0
HKD2_k127_1181381_7 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 444.0
HKD2_k127_1181381_8 CpXC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 399.0
HKD2_k127_1181381_9 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 351.0
HKD2_k127_1245215_0 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 1.014e-231 730.0
HKD2_k127_1245215_1 Malic enzyme, N-terminal domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 459.0
HKD2_k127_1245215_2 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 306.0
HKD2_k127_1245215_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000003098 159.0
HKD2_k127_126156_0 (ABC) transporter K06147,K11085 - - 2.894e-246 774.0
HKD2_k127_126156_1 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 522.0
HKD2_k127_126156_10 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000000000000000002171 153.0
HKD2_k127_126156_11 - - - - 0.0000000000000000000000000000000005138 146.0
HKD2_k127_126156_12 - - - - 0.000000000000000000000002993 107.0
HKD2_k127_126156_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000000000003551 100.0
HKD2_k127_126156_15 - - - - 0.0000000000000007663 79.0
HKD2_k127_126156_16 domain, Protein - - - 0.0000000004956 70.0
HKD2_k127_126156_18 Acyl-transferase K00655 - 2.3.1.51 0.00004286 49.0
HKD2_k127_126156_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 522.0
HKD2_k127_126156_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 426.0
HKD2_k127_126156_4 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 367.0
HKD2_k127_126156_5 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 362.0
HKD2_k127_126156_6 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 323.0
HKD2_k127_126156_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003492 257.0
HKD2_k127_126156_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
HKD2_k127_126156_9 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000000000000135 197.0
HKD2_k127_1300604_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 7.721e-210 665.0
HKD2_k127_1300604_1 Acetokinase family K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 533.0
HKD2_k127_1300604_2 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.00000000000000000000000000000000000000000000000000000000001539 212.0
HKD2_k127_1300604_3 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000001836 134.0
HKD2_k127_1300604_4 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.0000000000004266 70.0
HKD2_k127_1315656_0 DNA polymerase K02337,K14162 - 2.7.7.7 2.322e-203 669.0
HKD2_k127_1315656_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 502.0
HKD2_k127_1315656_10 - - - - 0.00000000000000000000000000000000000000000004059 165.0
HKD2_k127_1315656_11 - - - - 0.00000000000000000000000000000000000008879 157.0
HKD2_k127_1315656_13 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0001656 53.0
HKD2_k127_1315656_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 340.0
HKD2_k127_1315656_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 293.0
HKD2_k127_1315656_4 Hsp70 protein K04046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004538 269.0
HKD2_k127_1315656_5 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000001917 226.0
HKD2_k127_1315656_6 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000002209 212.0
HKD2_k127_1315656_7 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000003603 211.0
HKD2_k127_1315656_8 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000003099 193.0
HKD2_k127_1315656_9 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000006072 192.0
HKD2_k127_1319358_0 VWA domain containing CoxE-like protein K07114 - - 8.591e-234 749.0
HKD2_k127_1319358_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 496.0
HKD2_k127_1319358_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000001148 250.0
HKD2_k127_1319358_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000001511 211.0
HKD2_k127_1319358_4 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000003422 102.0
HKD2_k127_1319358_5 Protein of unknown function (DUF952) - - - 0.0000000000000000006347 99.0
HKD2_k127_1319358_6 Phospholipid methyltransferase - - - 0.000000000000002254 84.0
HKD2_k127_1322245_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1069.0
HKD2_k127_1322245_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 436.0
HKD2_k127_1322245_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 350.0
HKD2_k127_1322245_3 Formiminotransferase-cyclodeaminase - - - 0.0000000008333 64.0
HKD2_k127_1367069_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 3.179e-209 658.0
HKD2_k127_1367069_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
HKD2_k127_1367069_2 PFAM YbbR family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 334.0
HKD2_k127_1367069_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000001137 65.0
HKD2_k127_1385526_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 515.0
HKD2_k127_1385526_1 fad dependent oxidoreductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 411.0
HKD2_k127_1385526_10 - - - - 0.0000000000004818 70.0
HKD2_k127_1385526_12 virion core protein (lumpy skin disease virus) - - - 0.00001877 56.0
HKD2_k127_1385526_13 Clostripain family - - - 0.0003502 49.0
HKD2_k127_1385526_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 391.0
HKD2_k127_1385526_3 ABC 3 transport family K09816,K09819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 356.0
HKD2_k127_1385526_4 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 308.0
HKD2_k127_1385526_5 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 314.0
HKD2_k127_1385526_6 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 291.0
HKD2_k127_1385526_7 Two component transcriptional regulator, winged helix family K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007953 280.0
HKD2_k127_1385526_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000002302 183.0
HKD2_k127_1385526_9 Ferric reductase like transmembrane component - - - 0.00000000000000000000000000000006349 136.0
HKD2_k127_1418163_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 612.0
HKD2_k127_1418163_1 EDD domain protein, DegV family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 490.0
HKD2_k127_1418163_10 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000001446 106.0
HKD2_k127_1418163_11 GAF domain K02480 - 2.7.13.3 0.00001299 56.0
HKD2_k127_1418163_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 443.0
HKD2_k127_1418163_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 426.0
HKD2_k127_1418163_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 406.0
HKD2_k127_1418163_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001414 281.0
HKD2_k127_1418163_6 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001559 265.0
HKD2_k127_1418163_7 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000004348 238.0
HKD2_k127_1418163_8 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000001325 212.0
HKD2_k127_1418163_9 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000001529 134.0
HKD2_k127_1425771_0 SnoaL-like domain - - - 0.000000000000000000000000000008507 124.0
HKD2_k127_1425771_1 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000006201 74.0
HKD2_k127_1425771_2 Endonuclease Exonuclease Phosphatase - - - 0.000001114 60.0
HKD2_k127_1425771_3 Lipopolysaccharide assembly protein A domain - - - 0.00002967 53.0
HKD2_k127_1429877_0 Anaerobic dimethyl sulfoxide reductase, A subunit, DmsA YnfE K07306 - 1.8.5.3 1.13e-234 750.0
HKD2_k127_1429877_1 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 307.0
HKD2_k127_1429877_2 Dimethylsulfoxide reductase chain B K07307 - - 0.0000000000000000000000008317 104.0
HKD2_k127_1437172_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 543.0
HKD2_k127_1437172_1 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 296.0
HKD2_k127_1437172_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000005673 226.0
HKD2_k127_1437172_3 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000003966 207.0
HKD2_k127_1437172_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000001431 190.0
HKD2_k127_1448168_0 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 1.653e-310 972.0
HKD2_k127_1448168_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 610.0
HKD2_k127_1448168_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000000000002674 128.0
HKD2_k127_1448168_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000001315 78.0
HKD2_k127_1448168_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 608.0
HKD2_k127_1448168_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 517.0
HKD2_k127_1448168_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 434.0
HKD2_k127_1448168_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 299.0
HKD2_k127_1448168_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001298 271.0
HKD2_k127_1448168_7 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000902 216.0
HKD2_k127_1448168_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000009997 199.0
HKD2_k127_1448168_9 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000001447 154.0
HKD2_k127_1451926_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 324.0
HKD2_k127_1451926_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002557 222.0
HKD2_k127_1454297_0 ABC transporter permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 508.0
HKD2_k127_1454297_1 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 462.0
HKD2_k127_1454297_2 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 434.0
HKD2_k127_1454297_3 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 350.0
HKD2_k127_1454297_4 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 310.0
HKD2_k127_1454297_5 Helix-turn-helix domain, rpiR family - - - 0.00000000000000000000000000006347 127.0
HKD2_k127_1454297_6 Belongs to the uridine kinase family K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000004998 71.0
HKD2_k127_1454297_7 ABC-type Fe3 transport system, periplasmic component - - - 0.0000002684 59.0
HKD2_k127_1455400_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1173.0
HKD2_k127_1455400_1 PFAM CheR methyltransferase, SAM binding domain K00575,K13924 - 2.1.1.80,3.1.1.61 5.378e-225 713.0
HKD2_k127_1455400_10 PFAM CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001132 274.0
HKD2_k127_1455400_11 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000002585 259.0
HKD2_k127_1455400_12 helix_turn_helix, Lux Regulon K14979 - - 0.00000000000000000000000000000000000000000000000000000000000001114 222.0
HKD2_k127_1455400_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000002135 217.0
HKD2_k127_1455400_14 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000313 204.0
HKD2_k127_1455400_15 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000007052 184.0
HKD2_k127_1455400_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000005227 197.0
HKD2_k127_1455400_17 - K07403 - - 0.0000000000000000000000000000000000000000000000423 176.0
HKD2_k127_1455400_18 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000001239 139.0
HKD2_k127_1455400_19 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000008088 127.0
HKD2_k127_1455400_2 Beta-Casp domain K07576 - - 4.964e-195 618.0
HKD2_k127_1455400_20 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000277 101.0
HKD2_k127_1455400_21 Domain of unknown function (DUF3786) - - - 0.000000000000000000006354 102.0
HKD2_k127_1455400_22 FR47-like protein - - - 0.0004082 44.0
HKD2_k127_1455400_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 567.0
HKD2_k127_1455400_4 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 458.0
HKD2_k127_1455400_5 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 439.0
HKD2_k127_1455400_6 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 432.0
HKD2_k127_1455400_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 399.0
HKD2_k127_1455400_8 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 371.0
HKD2_k127_1455400_9 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 351.0
HKD2_k127_1464044_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1427.0
HKD2_k127_1464044_1 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 3.34e-198 631.0
HKD2_k127_1464044_10 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
HKD2_k127_1464044_11 FAD binding domain in molybdopterin dehydrogenase K03519,K12529 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000353 208.0
HKD2_k127_1464044_12 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000004698 192.0
HKD2_k127_1464044_13 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.00000000000000000000000000000000000000000000000123 181.0
HKD2_k127_1464044_14 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000001928 177.0
HKD2_k127_1464044_15 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000845 166.0
HKD2_k127_1464044_16 Protein of unknown function (DUF1361) - - - 0.0000000000000000000000000000000000000008114 156.0
HKD2_k127_1464044_17 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000001755 136.0
HKD2_k127_1464044_18 protein conserved in bacteria - - - 0.000000000000000000000000000002426 126.0
HKD2_k127_1464044_19 inorganic diphosphatase activity K01507 - 3.6.1.1 0.00000000000000000000000000000406 124.0
HKD2_k127_1464044_2 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 552.0
HKD2_k127_1464044_20 mannose-ethanolamine phosphotransferase activity K05288 - - 0.00000000000005543 85.0
HKD2_k127_1464044_3 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 541.0
HKD2_k127_1464044_4 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 426.0
HKD2_k127_1464044_5 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 354.0
HKD2_k127_1464044_6 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 356.0
HKD2_k127_1464044_7 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 342.0
HKD2_k127_1464044_8 inorganic diphosphatase activity K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 335.0
HKD2_k127_1464044_9 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 324.0
HKD2_k127_1510917_0 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001511 277.0
HKD2_k127_1510917_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000002463 237.0
HKD2_k127_1510917_10 response to heat K03668,K09914 - - 0.0000000000000000002365 102.0
HKD2_k127_1510917_11 Domain of unknown function (DUF4190) - - - 0.000000000003527 70.0
HKD2_k127_1510917_12 domain, Protein - - - 0.000000003988 69.0
HKD2_k127_1510917_13 PFAM regulatory protein LuxR K07689 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.00000002635 61.0
HKD2_k127_1510917_15 ABC-2 family transporter protein K01992 - - 0.0000001641 56.0
HKD2_k127_1510917_16 - - - - 0.0000139 54.0
HKD2_k127_1510917_17 Beta-lactamase - - - 0.0001911 49.0
HKD2_k127_1510917_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000001828 230.0
HKD2_k127_1510917_3 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000008829 240.0
HKD2_k127_1510917_4 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000005781 235.0
HKD2_k127_1510917_5 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000001235 182.0
HKD2_k127_1510917_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.000000000000000000000000007606 115.0
HKD2_k127_1510917_7 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000005531 114.0
HKD2_k127_1510917_8 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000008929 101.0
HKD2_k127_1520784_0 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 449.0
HKD2_k127_1581773_0 Zinc-binding dehydrogenase K22231 - - 2.715e-195 614.0
HKD2_k127_1581773_1 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 556.0
HKD2_k127_1581773_10 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000001967 210.0
HKD2_k127_1581773_11 HAD-hyrolase-like - - - 0.000000000000000003211 87.0
HKD2_k127_1581773_2 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 514.0
HKD2_k127_1581773_3 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 477.0
HKD2_k127_1581773_4 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 322.0
HKD2_k127_1581773_5 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 316.0
HKD2_k127_1581773_6 TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001086 286.0
HKD2_k127_1581773_7 helix_turn _helix lactose operon repressor K05499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003217 288.0
HKD2_k127_1581773_8 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 277.0
HKD2_k127_1581773_9 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000002028 227.0
HKD2_k127_1593283_0 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 437.0
HKD2_k127_1593283_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 387.0
HKD2_k127_1593283_2 TIGRFAM polymorphic outer membrane protein K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 378.0
HKD2_k127_1593283_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002432 209.0
HKD2_k127_1593283_4 - - - - 0.0000000002431 68.0
HKD2_k127_1598580_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000005014 221.0
HKD2_k127_1598580_1 Acyl-ACP thioesterase - - - 0.00000000000000000000000000000002749 135.0
HKD2_k127_1598580_2 TIGRFAM polymorphic outer membrane protein - - - 0.0000000000001059 85.0
HKD2_k127_1617766_0 acid phosphatase activity K01077 - 3.1.3.1 0.0000000000000000000000000000000000000009425 162.0
HKD2_k127_1617766_1 KR domain - - - 0.0000000000000002066 85.0
HKD2_k127_1617978_0 Selenocysteine-specific translation elongation factor K03833 - - 1.539e-243 767.0
HKD2_k127_1617978_1 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 600.0
HKD2_k127_1617978_12 Putative zinc-finger - - - 0.00000000000000000035 90.0
HKD2_k127_1617978_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 570.0
HKD2_k127_1617978_3 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 526.0
HKD2_k127_1617978_4 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 345.0
HKD2_k127_1617978_5 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
HKD2_k127_1617978_6 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 332.0
HKD2_k127_1617978_7 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 326.0
HKD2_k127_1617978_8 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 329.0
HKD2_k127_1617978_9 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000007941 226.0
HKD2_k127_1626725_0 Secreted repeat of unknown function - - - 0.000000000000000000000000000000002417 135.0
HKD2_k127_1626725_1 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.00000000000007778 83.0
HKD2_k127_1626725_3 photosynthesis - - - 0.00000006581 65.0
HKD2_k127_1656811_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0 1506.0
HKD2_k127_1656811_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 602.0
HKD2_k127_1656811_2 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 484.0
HKD2_k127_1656811_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004533 257.0
HKD2_k127_1656811_4 Methyltransferase domain - - - 0.0000000000000000000000000005992 122.0
HKD2_k127_1656811_5 PFAM glycosyl transferase group 1 - - - 0.00003771 48.0
HKD2_k127_1693647_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.03e-271 842.0
HKD2_k127_1693647_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.699e-246 765.0
HKD2_k127_1693647_10 protein conserved in bacteria - - - 0.00000004378 56.0
HKD2_k127_1693647_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 575.0
HKD2_k127_1693647_3 aminopeptidase activity K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 414.0
HKD2_k127_1693647_4 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 348.0
HKD2_k127_1693647_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 310.0
HKD2_k127_1693647_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003026 263.0
HKD2_k127_1693647_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000006021 184.0
HKD2_k127_1693647_8 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.00000000000000000000000000000000000000000001074 170.0
HKD2_k127_1693647_9 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000001209 102.0
HKD2_k127_1739424_0 PFAM Major Facilitator Superfamily K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 510.0
HKD2_k127_1739424_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 324.0
HKD2_k127_1739424_10 DinB superfamily - - - 0.00000002301 61.0
HKD2_k127_1739424_11 - - - - 0.000003635 50.0
HKD2_k127_1739424_2 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 323.0
HKD2_k127_1739424_3 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 294.0
HKD2_k127_1739424_4 esterase K03930 - - 0.00000000000000000000000000000000000000000000000000001223 198.0
HKD2_k127_1739424_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000001275 171.0
HKD2_k127_1739424_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000001689 145.0
HKD2_k127_1739424_7 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000008141 134.0
HKD2_k127_1739424_8 reductase K00059 - 1.1.1.100 0.00000000000000000000000000001849 126.0
HKD2_k127_1739424_9 CAAX protease self-immunity K07052 - - 0.000000000000000000005976 104.0
HKD2_k127_1752952_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 584.0
HKD2_k127_1752952_1 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 494.0
HKD2_k127_1752952_10 MFS/sugar transport protein - - - 0.00000000000002424 83.0
HKD2_k127_1752952_2 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 449.0
HKD2_k127_1752952_3 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 337.0
HKD2_k127_1752952_5 Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000003004 187.0
HKD2_k127_1752952_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000002661 139.0
HKD2_k127_1752952_7 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000002934 135.0
HKD2_k127_1752952_8 It is involved in the biological process described with transmembrane transport - GO:0007275,GO:0007568,GO:0008150,GO:0008340,GO:0010259,GO:0032501,GO:0032502,GO:0048856 - 0.000000000000000000000000007439 123.0
HKD2_k127_1752952_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000001298 83.0
HKD2_k127_1763539_0 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 2.563e-239 748.0
HKD2_k127_1763539_1 formate C-acetyltransferase activity K00656 - 2.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 590.0
HKD2_k127_1763539_2 Metallopeptidase family M24 K18829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 381.0
HKD2_k127_1763539_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000004166 241.0
HKD2_k127_1763539_4 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000009817 132.0
HKD2_k127_1773893_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 3.268e-227 712.0
HKD2_k127_1773893_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 387.0
HKD2_k127_1773893_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 336.0
HKD2_k127_1773893_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 258.0
HKD2_k127_1773893_4 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000000000000000000001381 198.0
HKD2_k127_1773893_5 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000002242 195.0
HKD2_k127_1773893_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000003193 165.0
HKD2_k127_1773893_7 AAA ATPase domain - - - 0.000000000000005812 89.0
HKD2_k127_1773893_8 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000006953 84.0
HKD2_k127_1773893_9 GNAT acetyltransferase - - - 0.000000000009117 75.0
HKD2_k127_1777220_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 342.0
HKD2_k127_1777220_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 334.0
HKD2_k127_1777220_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 308.0
HKD2_k127_1777220_3 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000001244 196.0
HKD2_k127_1777220_4 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000008457 118.0
HKD2_k127_1777220_5 CAAX protease self-immunity K07052 - - 0.000000000000000000005394 99.0
HKD2_k127_1786555_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 290.0
HKD2_k127_1831878_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 528.0
HKD2_k127_1831878_1 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 443.0
HKD2_k127_1831878_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 334.0
HKD2_k127_1831878_3 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000001128 234.0
HKD2_k127_1831878_4 PFAM secretion protein HlyD family protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000002199 233.0
HKD2_k127_1840637_0 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 418.0
HKD2_k127_1840637_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001248 290.0
HKD2_k127_1840637_2 InterPro IPR014922 - - - 0.0000000000000000000000000000000000000000000000008496 179.0
HKD2_k127_1840637_3 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000001989 179.0
HKD2_k127_1840637_4 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000002908 130.0
HKD2_k127_1840637_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000002916 68.0
HKD2_k127_1840637_6 protein secretion K03116 - - 0.000000004826 59.0
HKD2_k127_184161_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 500.0
HKD2_k127_184161_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 357.0
HKD2_k127_184161_10 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000000002652 158.0
HKD2_k127_184161_11 - - - - 0.00000000000000000000000000000000000000025 159.0
HKD2_k127_184161_12 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000000000000002734 140.0
HKD2_k127_184161_13 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000009824 124.0
HKD2_k127_184161_14 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000005159 84.0
HKD2_k127_184161_15 Polymer-forming cytoskeletal - - - 0.0000000000000001726 91.0
HKD2_k127_184161_16 Protein of unknown function (DUF3467) - - - 0.000000000000001074 80.0
HKD2_k127_184161_2 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
HKD2_k127_184161_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 319.0
HKD2_k127_184161_4 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 320.0
HKD2_k127_184161_5 DNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000111 240.0
HKD2_k127_184161_6 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000000000000001349 237.0
HKD2_k127_184161_7 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000002428 214.0
HKD2_k127_184161_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000318 189.0
HKD2_k127_184161_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000001822 175.0
HKD2_k127_1932850_0 Belongs to the glycosyl hydrolase 2 family - - - 5.549e-198 633.0
HKD2_k127_1932850_1 Belongs to the TPP enzyme family K00158,K03336 - 1.2.3.3,3.7.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 619.0
HKD2_k127_1932850_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001103 281.0
HKD2_k127_1932850_3 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 0.00000000000000000000000000000009475 141.0
HKD2_k127_1932850_4 Major Facilitator Superfamily - - - 0.0000000000000001502 85.0
HKD2_k127_193870_0 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 426.0
HKD2_k127_193870_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002954 279.0
HKD2_k127_193870_2 beta-galactosidase activity K01190,K17624 - 3.2.1.23,3.2.1.97 0.00000000000005641 71.0
HKD2_k127_1962182_0 Fibronectin type III-like domain K05349 - 3.2.1.21 9.223e-261 823.0
HKD2_k127_1962182_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 358.0
HKD2_k127_1962182_2 Periplasmic binding protein-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
HKD2_k127_2023574_0 PBP superfamily domain K03750,K07219 - 2.10.1.1 3.274e-288 897.0
HKD2_k127_2023574_1 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 2.732e-206 648.0
HKD2_k127_2023574_10 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000002192 194.0
HKD2_k127_2023574_11 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000002571 119.0
HKD2_k127_2023574_12 - - - - 0.000000000000000000000000008927 127.0
HKD2_k127_2023574_14 - - - - 0.00000000000000000768 89.0
HKD2_k127_2023574_15 Rhs_assc_core RHS repeat-associated core domain protein - - - 0.00000000000000003926 96.0
HKD2_k127_2023574_2 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 2.035e-203 638.0
HKD2_k127_2023574_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 499.0
HKD2_k127_2023574_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 320.0
HKD2_k127_2023574_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 339.0
HKD2_k127_2023574_6 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 308.0
HKD2_k127_2023574_7 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 291.0
HKD2_k127_2023574_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000007383 239.0
HKD2_k127_2023574_9 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000006549 245.0
HKD2_k127_203021_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 608.0
HKD2_k127_203021_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 478.0
HKD2_k127_203021_3 serine threonine protein kinase - - - 0.0000000000000007164 87.0
HKD2_k127_203021_4 SnoaL-like domain - - - 0.00009892 51.0
HKD2_k127_2102258_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.179e-288 908.0
HKD2_k127_2102258_1 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 447.0
HKD2_k127_2102258_2 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 399.0
HKD2_k127_2102258_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 331.0
HKD2_k127_2102258_4 TIGRFAM metal dependent phophohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 309.0
HKD2_k127_2102258_5 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007079 251.0
HKD2_k127_2102258_6 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000174 203.0
HKD2_k127_2106075_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.408e-244 762.0
HKD2_k127_2106075_1 BFD domain protein 2Fe-2S -binding domain protein K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 600.0
HKD2_k127_2106075_10 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000006032 290.0
HKD2_k127_2106075_11 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002834 266.0
HKD2_k127_2106075_12 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001251 241.0
HKD2_k127_2106075_13 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000307 210.0
HKD2_k127_2106075_14 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000001365 198.0
HKD2_k127_2106075_15 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000003231 165.0
HKD2_k127_2106075_16 Cupin domain - - - 0.00000000000000000000000491 104.0
HKD2_k127_2106075_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 510.0
HKD2_k127_2106075_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00113 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 505.0
HKD2_k127_2106075_4 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 492.0
HKD2_k127_2106075_5 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 439.0
HKD2_k127_2106075_6 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 415.0
HKD2_k127_2106075_7 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 381.0
HKD2_k127_2106075_8 family 4 K01222 - 3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 328.0
HKD2_k127_2106075_9 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006675 285.0
HKD2_k127_2117595_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 7.986e-215 677.0
HKD2_k127_2117595_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 481.0
HKD2_k127_2152272_0 Two component regulator propeller K17763 - - 4.739e-204 674.0
HKD2_k127_2152272_1 PFAM extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 402.0
HKD2_k127_2152272_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 341.0
HKD2_k127_2152272_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 329.0
HKD2_k127_2152272_4 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 288.0
HKD2_k127_2152272_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000001093 155.0
HKD2_k127_2152272_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000001082 136.0
HKD2_k127_2152272_7 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000255 90.0
HKD2_k127_2188818_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 383.0
HKD2_k127_2188818_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000162 272.0
HKD2_k127_2188818_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002742 257.0
HKD2_k127_2188818_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000001053 198.0
HKD2_k127_2188818_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000001538 80.0
HKD2_k127_2210203_0 COG0610 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases - - - 0.0000000000000000000000000000000000000000000000005714 180.0
HKD2_k127_2210203_1 Oxidoreductase K10678,K19286 - 1.5.1.39 0.00000000000000000000001233 110.0
HKD2_k127_2210203_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000001637 75.0
HKD2_k127_2210203_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000001992 63.0
HKD2_k127_2210203_4 SNARE associated Golgi protein - - - 0.00001774 47.0
HKD2_k127_2218426_0 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 569.0
HKD2_k127_2218426_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 492.0
HKD2_k127_2218426_10 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000006346 200.0
HKD2_k127_2218426_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001093 192.0
HKD2_k127_2218426_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000001227 182.0
HKD2_k127_2218426_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000001535 176.0
HKD2_k127_2218426_14 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000002846 158.0
HKD2_k127_2218426_15 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000003635 64.0
HKD2_k127_2218426_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 329.0
HKD2_k127_2218426_3 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 330.0
HKD2_k127_2218426_4 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 314.0
HKD2_k127_2218426_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 306.0
HKD2_k127_2218426_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004807 275.0
HKD2_k127_2218426_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004475 256.0
HKD2_k127_2218426_8 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000004605 242.0
HKD2_k127_2218426_9 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000003232 201.0
HKD2_k127_2337538_0 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 608.0
HKD2_k127_2337538_1 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 307.0
HKD2_k127_2337538_2 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.00000000000000000000001518 102.0
HKD2_k127_2337538_3 Ribosomal protein L11 methyltransferase (PrmA) K07755,K18064 - 2.1.1.137 0.0000000000007631 78.0
HKD2_k127_2337538_4 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000001058 56.0
HKD2_k127_2378335_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 567.0
HKD2_k127_2378335_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 375.0
HKD2_k127_2378335_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 347.0
HKD2_k127_2378335_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 342.0
HKD2_k127_2378335_4 ABC transporter K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 312.0
HKD2_k127_2378335_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004452 276.0
HKD2_k127_2378335_6 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 267.0
HKD2_k127_2378335_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002062 255.0
HKD2_k127_2378335_8 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000006526 243.0
HKD2_k127_2378335_9 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000001394 96.0
HKD2_k127_2453725_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 3.348e-221 699.0
HKD2_k127_2453725_1 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 286.0
HKD2_k127_2453725_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000002502 261.0
HKD2_k127_2467731_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 535.0
HKD2_k127_2467731_1 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 350.0
HKD2_k127_2467731_2 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000001859 224.0
HKD2_k127_2467731_3 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000137 194.0
HKD2_k127_2467731_4 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.00000000000000000000000000000000000000000000005835 173.0
HKD2_k127_2467731_5 PFAM phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000009521 164.0
HKD2_k127_2467731_6 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.0000000000000000000000000001875 118.0
HKD2_k127_2467731_7 - - - - 0.0000000000000000003114 98.0
HKD2_k127_2467731_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000521 95.0
HKD2_k127_2527705_0 UDP-N-acetylglucosamine 2-epimerase activity - - - 8.351e-198 633.0
HKD2_k127_2527705_1 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 523.0
HKD2_k127_2527705_10 Glycosyl transferase, family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 342.0
HKD2_k127_2527705_11 Protein of unknown function DUF115 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 322.0
HKD2_k127_2527705_12 cytidylyl-transferase K00983 - 2.7.7.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 303.0
HKD2_k127_2527705_13 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000499 272.0
HKD2_k127_2527705_14 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003912 254.0
HKD2_k127_2527705_15 Cytidylyltransferase K07257 - - 0.00000000000000000000000000000000000000000000000000000000000000000001438 243.0
HKD2_k127_2527705_16 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000292 217.0
HKD2_k127_2527705_17 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000001103 218.0
HKD2_k127_2527705_18 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000001488 198.0
HKD2_k127_2527705_19 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000000000000000000000000000000888 169.0
HKD2_k127_2527705_2 SAF K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 509.0
HKD2_k127_2527705_21 methyltransferase activity - - - 0.00000000000000000004973 100.0
HKD2_k127_2527705_22 Psort location CytoplasmicMembrane, score - - - 0.000000001038 71.0
HKD2_k127_2527705_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000004051 59.0
HKD2_k127_2527705_24 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.00004127 47.0
HKD2_k127_2527705_3 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 462.0
HKD2_k127_2527705_4 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 443.0
HKD2_k127_2527705_5 inositol 2-dehydrogenase activity K18431 - 2.7.7.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 379.0
HKD2_k127_2527705_6 Glycosyltransferase like family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 373.0
HKD2_k127_2527705_7 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 367.0
HKD2_k127_2527705_8 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 357.0
HKD2_k127_2527705_9 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 359.0
HKD2_k127_254300_0 FGGY family of carbohydrate kinases, N-terminal domain K00853 - 2.7.1.16 2.965e-281 872.0
HKD2_k127_254300_1 Alcohol dehydrogenase GroES-like domain K00004,K00008,K00098 - 1.1.1.14,1.1.1.264,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 346.0
HKD2_k127_254300_2 Metallopeptidase family M24 K18829 - - 0.0000000000000000000001466 98.0
HKD2_k127_254300_3 Class ii aldolase K01628,K03077 - 4.1.2.17,5.1.3.4 0.00000003289 55.0
HKD2_k127_2553894_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001658 291.0
HKD2_k127_2553894_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
HKD2_k127_2553894_2 Histidine kinase K03406,K07673,K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000004131 165.0
HKD2_k127_2553894_3 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.00000000000000000000005486 110.0
HKD2_k127_2553894_4 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000006775 106.0
HKD2_k127_2555917_0 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 370.0
HKD2_k127_2555917_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000002247 215.0
HKD2_k127_2555917_2 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000000000000000007701 209.0
HKD2_k127_2555917_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000004747 162.0
HKD2_k127_2555917_4 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000009847 119.0
HKD2_k127_2557550_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 609.0
HKD2_k127_2557550_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000007812 149.0
HKD2_k127_2557550_2 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000001645 118.0
HKD2_k127_2557550_3 Psort location CytoplasmicMembrane, score K07052 - - 0.000000004424 67.0
HKD2_k127_2557550_4 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000288 49.0
HKD2_k127_2557550_5 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0001283 47.0
HKD2_k127_2561220_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 8.533e-205 662.0
HKD2_k127_2561220_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004456 271.0
HKD2_k127_2561220_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000002435 238.0
HKD2_k127_2561220_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000003852 198.0
HKD2_k127_2561220_4 NUDIX domain - - - 0.000000000000000000006394 100.0
HKD2_k127_2567062_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 2.126e-251 782.0
HKD2_k127_2567062_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.195e-250 780.0
HKD2_k127_2567062_10 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 334.0
HKD2_k127_2567062_11 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 325.0
HKD2_k127_2567062_12 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 317.0
HKD2_k127_2567062_13 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 297.0
HKD2_k127_2567062_14 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006783 261.0
HKD2_k127_2567062_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
HKD2_k127_2567062_16 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000005015 220.0
HKD2_k127_2567062_17 PFAM glutamine amidotransferase class-I K07010 - - 0.000000000000000000000000000000000000000000000000000000000008714 215.0
HKD2_k127_2567062_18 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000001776 181.0
HKD2_k127_2567062_19 CYTH domain K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000000002214 180.0
HKD2_k127_2567062_2 PFAM AAA ATPase central domain protein K07478 - - 4.01e-207 653.0
HKD2_k127_2567062_20 NUDIX domain - - - 0.00000000000000000000000000000000000000000000002053 175.0
HKD2_k127_2567062_21 Acetyltransferase - - - 0.00000000000000000000000000000000000000000000005506 175.0
HKD2_k127_2567062_22 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000009934 155.0
HKD2_k127_2567062_23 Acyl-transferase - - - 0.0000000000000000000000000000000005291 141.0
HKD2_k127_2567062_24 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000001634 138.0
HKD2_k127_2567062_25 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000001127 126.0
HKD2_k127_2567062_26 acetyltransferase - - - 0.00000000000000000000000007913 113.0
HKD2_k127_2567062_27 Biotin-requiring enzyme - - - 0.000000000000000000000005183 108.0
HKD2_k127_2567062_28 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000008137 101.0
HKD2_k127_2567062_29 - - - - 0.000000000000002827 81.0
HKD2_k127_2567062_3 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 554.0
HKD2_k127_2567062_30 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00000000005759 69.0
HKD2_k127_2567062_31 CytoplasmicMembrane, score 9.99 - - - 0.0001888 56.0
HKD2_k127_2567062_4 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 556.0
HKD2_k127_2567062_5 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 434.0
HKD2_k127_2567062_7 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 429.0
HKD2_k127_2567062_8 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 389.0
HKD2_k127_2567062_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 348.0
HKD2_k127_2583026_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.115e-304 940.0
HKD2_k127_2583026_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 7.463e-231 728.0
HKD2_k127_2583026_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003043 241.0
HKD2_k127_2583026_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000001057 168.0
HKD2_k127_2583026_4 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000006959 168.0
HKD2_k127_2583026_5 methyltransferase - - - 0.000000000000000000000000000000000000009841 154.0
HKD2_k127_2583026_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000001804 115.0
HKD2_k127_2583172_0 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000005125 211.0
HKD2_k127_2583172_1 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000031 188.0
HKD2_k127_2583172_2 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000004086 118.0
HKD2_k127_2606231_0 PFAM magnesium chelatase ChlI subunit K07391 - - 9.133e-210 657.0
HKD2_k127_2606231_1 COG1520 FOG WD40-like repeat - - - 0.0002787 48.0
HKD2_k127_2609299_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009592 278.0
HKD2_k127_2609299_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000114 183.0
HKD2_k127_2609299_2 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000001257 115.0
HKD2_k127_2609299_3 antibiotic catabolic process - - - 0.0000000000000001021 93.0
HKD2_k127_2633902_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 452.0
HKD2_k127_2633902_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000001278 242.0
HKD2_k127_2633902_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000002519 133.0
HKD2_k127_2633902_3 glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000002083 115.0
HKD2_k127_2633902_4 ABC-2 type transporter K01992 - - 0.000000000000000000000004361 103.0
HKD2_k127_2653247_0 nuclear chromosome segregation - - - 3.758e-271 859.0
HKD2_k127_2653247_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 399.0
HKD2_k127_2653247_10 - - - - 0.00000000000000000000000000000000000002195 149.0
HKD2_k127_2653247_11 PFAM regulatory protein, MerR - - - 0.0000000000000000000000000001519 123.0
HKD2_k127_2653247_12 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000002428 121.0
HKD2_k127_2653247_13 LysM domain K07273,K22278 - 3.5.1.104 0.000000000000000000000000004903 119.0
HKD2_k127_2653247_15 Tfp pilus assembly protein FimV - - - 0.0002452 53.0
HKD2_k127_2653247_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 266.0
HKD2_k127_2653247_3 PFAM phospholipase D Transphosphatidylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008554 261.0
HKD2_k127_2653247_4 - - - - 0.0000000000000000000000000000000000000000000000000000000001632 211.0
HKD2_k127_2653247_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000004941 193.0
HKD2_k127_2653247_6 Transcriptional regulator K03724 - - 0.0000000000000000000000000000000000000000000009437 171.0
HKD2_k127_2653247_7 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000002377 169.0
HKD2_k127_2653247_8 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000009014 163.0
HKD2_k127_2653247_9 DinB family - - - 0.00000000000000000000000000000000000001648 147.0
HKD2_k127_2677573_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 387.0
HKD2_k127_2677573_1 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 317.0
HKD2_k127_2677573_10 CAAX protease self-immunity K07052 - - 0.00000000000000000002562 99.0
HKD2_k127_2677573_11 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000003233 99.0
HKD2_k127_2677573_12 - - - - 0.000000000000002414 80.0
HKD2_k127_2677573_13 - - - - 0.00000000109 70.0
HKD2_k127_2677573_2 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 289.0
HKD2_k127_2677573_3 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001111 295.0
HKD2_k127_2677573_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005256 253.0
HKD2_k127_2677573_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001109 253.0
HKD2_k127_2677573_6 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000002669 197.0
HKD2_k127_2677573_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000005261 201.0
HKD2_k127_2677573_8 metal-dependent membrane protease K07052 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071586,GO:0071704,GO:0071944,GO:0080120,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000015 147.0
HKD2_k127_2677573_9 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.000000000000000000000000000000675 132.0
HKD2_k127_268018_0 formate C-acetyltransferase glycine radical - - - 2.721e-301 936.0
HKD2_k127_268018_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.937e-240 762.0
HKD2_k127_268018_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 572.0
HKD2_k127_268018_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 527.0
HKD2_k127_268018_4 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 510.0
HKD2_k127_268018_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 428.0
HKD2_k127_268018_6 heme binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 353.0
HKD2_k127_268018_7 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001489 261.0
HKD2_k127_268018_8 PFAM Vitamin K epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000233 224.0
HKD2_k127_268018_9 protein-(glutamine-N5) methyltransferase activity K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000931 176.0
HKD2_k127_2689252_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 613.0
HKD2_k127_2689252_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 430.0
HKD2_k127_2689252_2 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 360.0
HKD2_k127_2689252_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 346.0
HKD2_k127_2696568_0 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 527.0
HKD2_k127_2696568_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 505.0
HKD2_k127_2696568_10 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 409.0
HKD2_k127_2696568_11 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 398.0
HKD2_k127_2696568_12 Epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 346.0
HKD2_k127_2696568_13 PFAM Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 335.0
HKD2_k127_2696568_14 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 342.0
HKD2_k127_2696568_15 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 329.0
HKD2_k127_2696568_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 297.0
HKD2_k127_2696568_17 Phosphoesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 296.0
HKD2_k127_2696568_18 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004841 276.0
HKD2_k127_2696568_19 glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000001471 257.0
HKD2_k127_2696568_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 496.0
HKD2_k127_2696568_20 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000005671 221.0
HKD2_k127_2696568_21 - - - - 0.00000000000000000000000000000000000000000000000001977 184.0
HKD2_k127_2696568_22 PFAM glycoside hydrolase, family 18 - - - 0.000000000000000000000000000000000000002908 164.0
HKD2_k127_2696568_24 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000004944 155.0
HKD2_k127_2696568_25 Parallel beta-helix repeats - - - 0.000000000000000000000000000000002957 150.0
HKD2_k127_2696568_26 response regulator K02479,K07684,K07685 - - 0.0000000000000000000000000000004484 131.0
HKD2_k127_2696568_27 Fibronectin type 3 domain - - - 0.00000000000000000000000000002029 129.0
HKD2_k127_2696568_28 polygalacturonase activity - - - 0.000000000000000000000000001394 128.0
HKD2_k127_2696568_29 - - - - 0.00000000000000000000001842 101.0
HKD2_k127_2696568_3 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005301 484.0
HKD2_k127_2696568_30 aminopeptidase activity - - - 0.00000000000001441 83.0
HKD2_k127_2696568_31 Phosphodiester glycosidase - - - 0.00000000008084 75.0
HKD2_k127_2696568_32 tetratricopeptide repeat - - - 0.000007305 58.0
HKD2_k127_2696568_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 477.0
HKD2_k127_2696568_5 PFAM Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 464.0
HKD2_k127_2696568_6 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 456.0
HKD2_k127_2696568_7 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 441.0
HKD2_k127_2696568_8 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 414.0
HKD2_k127_2696568_9 PFAM Glycosyl transferase, group 1 K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 417.0
HKD2_k127_2774438_0 belongs to the aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 566.0
HKD2_k127_2774438_1 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000002352 214.0
HKD2_k127_2774438_2 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 0.00002166 59.0
HKD2_k127_2795606_0 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 563.0
HKD2_k127_2795606_1 glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 413.0
HKD2_k127_2817291_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.602e-297 934.0
HKD2_k127_2817291_1 PFAM Dak phosphatase K07030 - - 3.735e-213 676.0
HKD2_k127_2817291_10 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000001536 166.0
HKD2_k127_2817291_11 Asp23 family, cell envelope-related function - - - 0.000000000000000000000000000000000000003404 149.0
HKD2_k127_2817291_12 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000002864 136.0
HKD2_k127_2817291_13 ribosomal protein L28 K02902 - - 0.00000000000000004315 81.0
HKD2_k127_2817291_14 EDD domain protein, DegV family - - - 0.0000000000008157 79.0
HKD2_k127_2817291_15 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000008966 61.0
HKD2_k127_2817291_2 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K07303 - 1.3.99.16 2.063e-196 636.0
HKD2_k127_2817291_3 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 454.0
HKD2_k127_2817291_4 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 368.0
HKD2_k127_2817291_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007266 249.0
HKD2_k127_2817291_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001859 246.0
HKD2_k127_2817291_7 [2Fe-2S] binding domain K07302,K18029 - 1.17.2.1,1.3.99.16 0.00000000000000000000000000000000000000000000000000000264 196.0
HKD2_k127_2817291_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000000000000000000464 194.0
HKD2_k127_2817291_9 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000825 186.0
HKD2_k127_281965_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 364.0
HKD2_k127_281965_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000003195 237.0
HKD2_k127_281965_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004403 258.0
HKD2_k127_281965_3 amino acid-binding ACT domain protein K04767 - - 0.00000000000000000000000000000000000000000000000000000000000104 217.0
HKD2_k127_281965_4 Histidine kinase - - - 0.000001105 51.0
HKD2_k127_2878863_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00207,K00219,K00317,K02293,K10797,K12527,K17723 - 1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9 6.527e-261 827.0
HKD2_k127_2878863_1 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 508.0
HKD2_k127_2878863_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 - 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 436.0
HKD2_k127_2878863_3 PFAM Glycoside hydrolase family 42 domain protein K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 287.0
HKD2_k127_2878863_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003536 276.0
HKD2_k127_2878863_5 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000125 133.0
HKD2_k127_2878863_6 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.000000000000000000836 96.0
HKD2_k127_2885906_0 DNA-binding transcription factor activity K02316,K04096,K20421 - 2.1.1.303 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 542.0
HKD2_k127_2885906_1 - - - - 0.0000000000000000002793 90.0
HKD2_k127_2885906_2 Phage terminase, small subunit - - - 0.000003728 54.0
HKD2_k127_2885906_3 DNA excision - - - 0.0004131 46.0
HKD2_k127_2911884_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 3.916e-253 793.0
HKD2_k127_2911884_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.121e-234 734.0
HKD2_k127_2911884_10 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 468.0
HKD2_k127_2911884_11 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 447.0
HKD2_k127_2911884_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 396.0
HKD2_k127_2911884_13 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 385.0
HKD2_k127_2911884_14 L-lysine catabolic process to acetate K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 326.0
HKD2_k127_2911884_15 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 317.0
HKD2_k127_2911884_16 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 305.0
HKD2_k127_2911884_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002086 281.0
HKD2_k127_2911884_18 CBS domain containing protein K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000073 287.0
HKD2_k127_2911884_19 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000048 268.0
HKD2_k127_2911884_2 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 3.138e-218 700.0
HKD2_k127_2911884_20 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005834 269.0
HKD2_k127_2911884_21 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005415 249.0
HKD2_k127_2911884_22 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.000000000000000000000000000000000000000000000000000000006265 206.0
HKD2_k127_2911884_23 Haloacid dehalogenase domain protein hydrolase - - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
HKD2_k127_2911884_24 - - - - 0.000000000000000000000000000000000000000000000000000000247 205.0
HKD2_k127_2911884_25 PFAM Maf family protein K06287 - - 0.0000000000000000000000000000000000000000000000000000002829 204.0
HKD2_k127_2911884_26 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000002106 215.0
HKD2_k127_2911884_27 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000003301 170.0
HKD2_k127_2911884_28 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000000000000000000007775 169.0
HKD2_k127_2911884_29 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000003785 142.0
HKD2_k127_2911884_3 PFAM ABC transporter related K02056 - 3.6.3.17 4.222e-202 641.0
HKD2_k127_2911884_30 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000004871 139.0
HKD2_k127_2911884_31 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000002318 133.0
HKD2_k127_2911884_32 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.000000000000000000000000000002557 134.0
HKD2_k127_2911884_33 DNA-binding transcription factor activity K04096 - - 0.00000000000000000000000000001505 121.0
HKD2_k127_2911884_34 phosphorelay signal transduction system - - - 0.0000000000000000000000001061 120.0
HKD2_k127_2911884_35 PFAM Archaeal ATPase K06921 - - 0.0000000000000000000006037 109.0
HKD2_k127_2911884_36 Protein of unknown function (DUF559) - - - 0.0000000000000000000008156 97.0
HKD2_k127_2911884_37 - - - - 0.000000000002662 68.0
HKD2_k127_2911884_39 Putative sensor - - - 0.0005817 44.0
HKD2_k127_2911884_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 553.0
HKD2_k127_2911884_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 545.0
HKD2_k127_2911884_6 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 535.0
HKD2_k127_2911884_7 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 528.0
HKD2_k127_2911884_8 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 507.0
HKD2_k127_2911884_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 504.0
HKD2_k127_2927779_0 all-trans-retinol 13,14-reductase activity K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 531.0
HKD2_k127_2927779_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 370.0
HKD2_k127_2927779_2 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.0000000000000000000000000000000000000000000000001201 182.0
HKD2_k127_2927779_3 Uncharacterized protein family, UPF0114 - - - 0.00000000000000006381 86.0
HKD2_k127_2933968_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000005398 121.0
HKD2_k127_2933968_1 coenzyme F420 binding - - - 0.0000000000000000000001516 103.0
HKD2_k127_2933968_2 transcriptional regulator, LuxR family - - - 0.0001479 46.0
HKD2_k127_2959059_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002073 261.0
HKD2_k127_2959059_1 cellulase activity K01179 - 3.2.1.4 0.000000000003587 68.0
HKD2_k127_2959904_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 343.0
HKD2_k127_2966880_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 278.0
HKD2_k127_2966880_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002434 272.0
HKD2_k127_2966880_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001038 269.0
HKD2_k127_2966880_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000006566 184.0
HKD2_k127_2966880_4 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000005398 121.0
HKD2_k127_2966880_5 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000006518 98.0
HKD2_k127_2966880_6 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000001666 78.0
HKD2_k127_3000476_0 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 535.0
HKD2_k127_3000476_1 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 426.0
HKD2_k127_3000476_2 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 417.0
HKD2_k127_3000476_3 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 322.0
HKD2_k127_3000476_4 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 289.0
HKD2_k127_3000476_5 -O-antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006097 277.0
HKD2_k127_3000476_6 domain, Protein - - - 0.0000000000000000000000000000000236 128.0
HKD2_k127_3000476_7 COG3944 Capsular polysaccharide biosynthesis protein K08252 - 2.7.10.1 0.0008194 49.0
HKD2_k127_302265_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 468.0
HKD2_k127_302265_1 PFAM Glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 312.0
HKD2_k127_302265_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000005899 173.0
HKD2_k127_302265_3 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000000000000000000000000001714 157.0
HKD2_k127_302265_4 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 0.0005704 48.0
HKD2_k127_3041175_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 307.0
HKD2_k127_3041175_1 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008188 277.0
HKD2_k127_3041175_2 Helix-turn-helix domain - - - 0.00005834 50.0
HKD2_k127_3104231_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 492.0
HKD2_k127_3104231_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000451 236.0
HKD2_k127_3104231_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005979 233.0
HKD2_k127_3104231_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000001383 72.0
HKD2_k127_3146772_0 IMP dehydrogenase activity K03406,K15371 - 1.4.1.2 3.843e-223 707.0
HKD2_k127_3146772_1 - - - - 1.335e-199 630.0
HKD2_k127_3146772_2 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 3.399e-195 629.0
HKD2_k127_3146772_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 458.0
HKD2_k127_3146772_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 450.0
HKD2_k127_3146772_5 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
HKD2_k127_3146772_6 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000003692 150.0
HKD2_k127_3160096_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 6.85e-232 723.0
HKD2_k127_3160096_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 579.0
HKD2_k127_3160096_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001089 264.0
HKD2_k127_3160096_11 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000006794 220.0
HKD2_k127_3160096_12 - - - - 0.0000000000000000000000000000000000000000002479 176.0
HKD2_k127_3160096_13 domain, Protein - - - 0.000000000000000000000000000000007251 139.0
HKD2_k127_3160096_15 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000007559 69.0
HKD2_k127_3160096_16 - - - - 0.000000003612 61.0
HKD2_k127_3160096_2 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 490.0
HKD2_k127_3160096_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 482.0
HKD2_k127_3160096_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 430.0
HKD2_k127_3160096_5 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 383.0
HKD2_k127_3160096_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 374.0
HKD2_k127_3160096_7 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 331.0
HKD2_k127_3160096_8 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 297.0
HKD2_k127_3160096_9 PFAM LmbE family protein K18455 - 3.5.1.115 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 293.0
HKD2_k127_3190868_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 9.482e-318 977.0
HKD2_k127_3190868_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.209e-209 659.0
HKD2_k127_3190868_10 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000000000000000004824 192.0
HKD2_k127_3190868_11 - - - - 0.00003012 50.0
HKD2_k127_3190868_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 572.0
HKD2_k127_3190868_3 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 452.0
HKD2_k127_3190868_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 356.0
HKD2_k127_3190868_5 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 334.0
HKD2_k127_3190868_6 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 304.0
HKD2_k127_3190868_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 295.0
HKD2_k127_3190868_8 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000003432 226.0
HKD2_k127_3190868_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000001809 213.0
HKD2_k127_3309495_0 ABC transporter (Permease) K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000023 248.0
HKD2_k127_3309495_1 organic phosphonate transmembrane transporter activity K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000001164 247.0
HKD2_k127_3309495_2 FMN binding - - - 0.00000000000000000000000000000000000001437 150.0
HKD2_k127_3309495_3 lactoylglutathione lyase activity - - - 0.000000000000000000000007139 106.0
HKD2_k127_3349762_0 SMART Elongator protein 3 MiaB NifB - - - 1.711e-234 737.0
HKD2_k127_3349762_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 442.0
HKD2_k127_3349762_2 PFAM sugar transferase - - - 0.00000000000000000000000000000001502 134.0
HKD2_k127_3349762_3 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.000000000000000000000000000003507 121.0
HKD2_k127_337174_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.512e-209 657.0
HKD2_k127_337174_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 5.46e-208 651.0
HKD2_k127_337174_10 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000006281 222.0
HKD2_k127_337174_11 Ig-like domain from next to BRCA1 gene K13276 - - 0.00000000000000000000000000000000000000000000001369 185.0
HKD2_k127_337174_12 dipeptide transport K02035 - - 0.0000000000000000000000000000000000005218 146.0
HKD2_k127_337174_13 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000006783 141.0
HKD2_k127_337174_14 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000000004413 117.0
HKD2_k127_337174_15 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000005679 108.0
HKD2_k127_337174_17 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000000000007017 106.0
HKD2_k127_337174_18 PFAM HD domain - - - 0.000000000000001362 84.0
HKD2_k127_337174_19 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000005789 70.0
HKD2_k127_337174_2 PFAM VanW family protein - - - 4.074e-202 647.0
HKD2_k127_337174_20 PBS lyase HEAT-like repeat - - - 0.00000006203 62.0
HKD2_k127_337174_21 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01761 - 2.5.1.48,4.4.1.11 0.000009705 49.0
HKD2_k127_337174_3 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 424.0
HKD2_k127_337174_4 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 387.0
HKD2_k127_337174_5 PFAM purine or other phosphorylase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 343.0
HKD2_k127_337174_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 320.0
HKD2_k127_337174_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 311.0
HKD2_k127_337174_8 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000001263 249.0
HKD2_k127_337174_9 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000005266 228.0
HKD2_k127_3388833_0 PFAM C4-dicarboxylate anaerobic carrier-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 452.0
HKD2_k127_3388833_1 Peptidase dimerisation domain K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 379.0
HKD2_k127_3388833_10 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000001585 80.0
HKD2_k127_3388833_11 SdpI/YhfL protein family - - - 0.000000000001169 72.0
HKD2_k127_3388833_2 amidohydrolase K21613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 357.0
HKD2_k127_3388833_3 2-aminoethylphosphonate-pyruvate transaminase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 295.0
HKD2_k127_3388833_4 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000006721 207.0
HKD2_k127_3388833_5 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000006901 199.0
HKD2_k127_3388833_6 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000005613 194.0
HKD2_k127_3388833_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000001039 164.0
HKD2_k127_3388833_8 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000001652 160.0
HKD2_k127_3388833_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000008615 111.0
HKD2_k127_3419939_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 290.0
HKD2_k127_3419939_1 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000000919 199.0
HKD2_k127_3419939_2 DinB family - - - 0.0000000000000000000000000000000000000000001204 164.0
HKD2_k127_3419939_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000248 158.0
HKD2_k127_3490_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1078.0
HKD2_k127_3490_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 588.0
HKD2_k127_3490_2 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 413.0
HKD2_k127_3490_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 404.0
HKD2_k127_3490_5 - - - - 0.0000000000000000000000000000000000000000003348 176.0
HKD2_k127_3490_6 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000009605 105.0
HKD2_k127_3490_7 Fungalysin metallopeptidase (M36) - - - 0.0000000000000001189 93.0
HKD2_k127_3493748_0 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 466.0
HKD2_k127_3493748_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000004153 240.0
HKD2_k127_3493748_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001275 226.0
HKD2_k127_3493748_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000815 180.0
HKD2_k127_3493748_4 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000007215 179.0
HKD2_k127_3493748_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000005455 146.0
HKD2_k127_3493748_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000003681 136.0
HKD2_k127_3493748_7 O-acyltransferase activity K00661 - 2.3.1.79 0.00000000000000000000000001329 117.0
HKD2_k127_3493748_8 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000002146 97.0
HKD2_k127_352939_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.054e-204 644.0
HKD2_k127_352939_1 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 465.0
HKD2_k127_352939_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 359.0
HKD2_k127_352939_3 beta-lactamase domain protein K05555 - - 0.000000000000000000000000000000006293 139.0
HKD2_k127_352939_4 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.000000000000000000000000000271 123.0
HKD2_k127_352939_5 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000008364 113.0
HKD2_k127_3588196_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 1.03e-271 852.0
HKD2_k127_3588196_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 456.0
HKD2_k127_3588196_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001064 305.0
HKD2_k127_3588196_3 - - - - 0.00000002965 65.0
HKD2_k127_363433_0 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 9.805e-229 719.0
HKD2_k127_363433_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 522.0
HKD2_k127_363433_2 PFAM zinc iron permease K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 349.0
HKD2_k127_363433_3 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000000002875 159.0
HKD2_k127_363433_4 Protein of unknown function (DUF402) - - - 0.0000000000000000000000000000000002862 139.0
HKD2_k127_363433_5 Sugar ABC transporter permease K10234 - - 0.00000000000000000000000000003777 118.0
HKD2_k127_363433_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000001797 69.0
HKD2_k127_3637322_0 ABC transporter transmembrane region - - - 1.739e-230 728.0
HKD2_k127_3637322_1 (ABC) transporter K06147 - - 1.21e-215 685.0
HKD2_k127_3637322_2 domain, Protein K01212,K12287,K20276 - 3.2.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000371 261.0
HKD2_k127_3637322_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000003639 225.0
HKD2_k127_36638_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1034.0
HKD2_k127_36638_1 Belongs to the carbamoyltransferase HypF family K04656 - - 2.375e-270 854.0
HKD2_k127_36638_10 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000009946 226.0
HKD2_k127_36638_11 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000009579 194.0
HKD2_k127_36638_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000003534 139.0
HKD2_k127_36638_13 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000001771 113.0
HKD2_k127_36638_14 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000004553 109.0
HKD2_k127_36638_16 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000006038 85.0
HKD2_k127_36638_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.384e-224 718.0
HKD2_k127_36638_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 563.0
HKD2_k127_36638_4 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 529.0
HKD2_k127_36638_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 508.0
HKD2_k127_36638_6 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 435.0
HKD2_k127_36638_7 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 402.0
HKD2_k127_36638_8 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
HKD2_k127_36638_9 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001744 256.0
HKD2_k127_3798151_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000001422 225.0
HKD2_k127_3798151_1 - - - - 0.000000000000000000000000000000000000001737 157.0
HKD2_k127_3812881_0 Amidohydrolase family K01464,K01466 - 3.5.2.2,3.5.2.5 3.175e-227 711.0
HKD2_k127_3812881_1 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 483.0
HKD2_k127_3812881_2 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 406.0
HKD2_k127_3812881_3 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.0000000000000000000000000000000000000000000007161 171.0
HKD2_k127_3835012_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 5.911e-240 752.0
HKD2_k127_3835012_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 485.0
HKD2_k127_3835012_2 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 476.0
HKD2_k127_3835012_3 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 340.0
HKD2_k127_3835012_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003977 284.0
HKD2_k127_3835012_5 DinB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001579 254.0
HKD2_k127_3835012_6 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001719 259.0
HKD2_k127_3835012_7 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000299 210.0
HKD2_k127_3835012_8 Aminoacyl-tRNA editing domain K01284 - 3.4.15.5 0.0000000000000000000000000000000000000000000000000000000003143 205.0
HKD2_k127_3835012_9 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000002962 188.0
HKD2_k127_3844267_0 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 576.0
HKD2_k127_3844267_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 561.0
HKD2_k127_3844267_10 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000001654 146.0
HKD2_k127_3844267_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 380.0
HKD2_k127_3844267_3 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 362.0
HKD2_k127_3844267_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 323.0
HKD2_k127_3844267_5 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
HKD2_k127_3844267_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000007654 252.0
HKD2_k127_3844267_7 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000001749 198.0
HKD2_k127_3844267_8 PFAM PfkB domain protein K16328 - 2.7.1.83 0.0000000000000000000000000000000000000000000000005035 182.0
HKD2_k127_3844267_9 PHP-associated - - - 0.000000000000000000000000000000000000002493 155.0
HKD2_k127_3882160_0 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 2.615e-200 646.0
HKD2_k127_3882160_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 571.0
HKD2_k127_3882160_10 Binding-protein-dependent transport system inner membrane component K02026,K05815,K17243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 359.0
HKD2_k127_3882160_11 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 358.0
HKD2_k127_3882160_12 Glycosyl hydrolases family 16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
HKD2_k127_3882160_13 myo-inosose-2 dehydratase activity K10709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 303.0
HKD2_k127_3882160_14 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004022 276.0
HKD2_k127_3882160_15 carbohydrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003958 279.0
HKD2_k127_3882160_16 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000005561 252.0
HKD2_k127_3882160_17 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003142 247.0
HKD2_k127_3882160_18 Shikimate kinase K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000000004247 177.0
HKD2_k127_3882160_19 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000003746 150.0
HKD2_k127_3882160_2 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 534.0
HKD2_k127_3882160_20 regulatory protein, arsR - - - 0.0000000000000000000000000000000000002452 143.0
HKD2_k127_3882160_21 - - - - 0.000000000000000000000000000000008525 149.0
HKD2_k127_3882160_22 DGC domain - - - 0.00000000000000000000000000000001132 137.0
HKD2_k127_3882160_23 OsmC-like protein - - - 0.00000000000000000000000000000001636 132.0
HKD2_k127_3882160_24 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000000000000000000002342 126.0
HKD2_k127_3882160_25 - - - - 0.0000000000000000000000000000002815 126.0
HKD2_k127_3882160_27 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000001764 126.0
HKD2_k127_3882160_28 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000008884 120.0
HKD2_k127_3882160_29 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000000000000000000007956 111.0
HKD2_k127_3882160_3 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 518.0
HKD2_k127_3882160_30 Putative Fe-S cluster - - - 0.00000000000000000000000001734 115.0
HKD2_k127_3882160_31 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000006304 105.0
HKD2_k127_3882160_32 DGC domain - - - 0.0000000000000000001011 94.0
HKD2_k127_3882160_34 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000216 67.0
HKD2_k127_3882160_35 - - - - 0.0000000001449 66.0
HKD2_k127_3882160_36 nitrogen fixation - - - 0.000004693 58.0
HKD2_k127_3882160_4 Belongs to the ABC transporter superfamily K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 493.0
HKD2_k127_3882160_5 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 488.0
HKD2_k127_3882160_6 Belongs to the ABC transporter superfamily K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 431.0
HKD2_k127_3882160_7 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 401.0
HKD2_k127_3882160_8 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 398.0
HKD2_k127_3882160_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 373.0
HKD2_k127_3886272_0 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 344.0
HKD2_k127_3886272_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 342.0
HKD2_k127_3886272_2 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003716 250.0
HKD2_k127_3886272_3 polysaccharide deacetylase K01406 - 3.4.24.40 0.0000000000000000000000000000000000000000000000009957 190.0
HKD2_k127_3886272_4 Zinc metalloprotease (Elastase) K01186,K05994,K21449 - 3.2.1.18,3.4.11.10 0.00000000000000000000000000000000005886 151.0
HKD2_k127_3886272_6 dihydrofolate reductase activity - - - 0.000000000000000000000006727 101.0
HKD2_k127_3886272_7 Septum formation initiator - - - 0.00000000000001725 78.0
HKD2_k127_3906604_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000008644 213.0
HKD2_k127_3906604_2 WD-40 repeat protein - - - 0.0000000000000000000000000000000000000003452 171.0
HKD2_k127_3906604_3 Transposase IS200 like - - - 0.000000000000000000000000000000000000004697 153.0
HKD2_k127_3906604_4 - - - - 0.000000000000000000000000000000000504 136.0
HKD2_k127_3906604_5 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000003445 136.0
HKD2_k127_3906604_6 transmembrane transporter activity K05820 - - 0.000000000000005219 82.0
HKD2_k127_3906604_7 Domain of unknown function (DU1801) - - - 0.000000001268 64.0
HKD2_k127_3935560_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004944 527.0
HKD2_k127_3935560_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 382.0
HKD2_k127_3935560_10 - - - - 0.00002784 55.0
HKD2_k127_3935560_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 304.0
HKD2_k127_3935560_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001743 220.0
HKD2_k127_3935560_4 CAAX protease self-immunity - - - 0.00000000000000000000000000001724 128.0
HKD2_k127_3935560_5 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.000000000000000000000003809 112.0
HKD2_k127_3935560_6 Domain of unknown function (DUF333) K09712 - - 0.0000000000000000000005528 110.0
HKD2_k127_3935560_7 - - - - 0.00000001672 60.0
HKD2_k127_3935560_8 Acetyltransferase (GNAT) domain - - - 0.00000004345 61.0
HKD2_k127_3935560_9 CAAX amino terminal protease family protein K07052 - - 0.0000009398 60.0
HKD2_k127_3939930_0 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 503.0
HKD2_k127_3939930_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 424.0
HKD2_k127_3939930_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006534 275.0
HKD2_k127_3939930_3 - - - - 0.0000000000000000000000000000000000000000000000000002609 192.0
HKD2_k127_3939930_4 - - - - 0.000000000000000000000000000000000000000000003464 169.0
HKD2_k127_3944251_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1361.0
HKD2_k127_3944251_1 ABC transporter, transmembrane region K06147 - - 3.794e-269 841.0
HKD2_k127_3944251_10 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000002154 184.0
HKD2_k127_3944251_11 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000001707 181.0
HKD2_k127_3944251_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K13891,K15582 - - 0.00000000000000000000000000000000000000007678 174.0
HKD2_k127_3944251_13 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000003511 122.0
HKD2_k127_3944251_14 iron-sulfur cluster assembly - - - 0.0000000000000000000000000001804 115.0
HKD2_k127_3944251_15 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15585 - - 0.0000000000000000001298 100.0
HKD2_k127_3944251_16 DNA-binding transcription factor activity - - - 0.0000000000000000005266 93.0
HKD2_k127_3944251_17 Domain of unknown function (DUF4870) K09940 - - 0.00005935 52.0
HKD2_k127_3944251_2 ABC-type multidrug transport system ATPase and permease K06147 - - 1.147e-246 783.0
HKD2_k127_3944251_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 560.0
HKD2_k127_3944251_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 387.0
HKD2_k127_3944251_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 391.0
HKD2_k127_3944251_6 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005987 290.0
HKD2_k127_3944251_7 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
HKD2_k127_3944251_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 265.0
HKD2_k127_3944251_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000005367 237.0
HKD2_k127_3947389_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
HKD2_k127_3947389_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000002766 183.0
HKD2_k127_3947389_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000002414 158.0
HKD2_k127_3947389_3 Ndr family - - - 0.000000000000000000000000000001022 127.0
HKD2_k127_3986442_0 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000051 224.0
HKD2_k127_3986442_1 Pas domain s-box - - - 0.0000000000000000000000000000000000000000000000000000134 213.0
HKD2_k127_3986442_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000461 109.0
HKD2_k127_3986442_3 - - - - 0.00000000001071 69.0
HKD2_k127_3986442_4 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0003507 45.0
HKD2_k127_4054194_0 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 452.0
HKD2_k127_4054194_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 297.0
HKD2_k127_4054194_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 294.0
HKD2_k127_4054194_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000001339 198.0
HKD2_k127_4054194_4 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000001321 201.0
HKD2_k127_4054194_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000005518 187.0
HKD2_k127_4054194_6 sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000005024 164.0
HKD2_k127_4054194_7 WD40 repeats - - - 0.0007259 45.0
HKD2_k127_4083626_0 Glycosyl transferase family group 2 K07011 - - 0.0000000000000000000000000000000000000000000000000008422 195.0
HKD2_k127_4083626_1 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000000000003354 137.0
HKD2_k127_4083626_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000005088 128.0
HKD2_k127_4083626_3 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000001176 98.0
HKD2_k127_408439_0 PFAM AAA-4 family protein K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 368.0
HKD2_k127_408439_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 349.0
HKD2_k127_408439_2 Baseplate J-like protein K01218 - 3.2.1.78 0.00000000000000000000000000000000000000000000000000000000000000001806 243.0
HKD2_k127_408439_3 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000005981 225.0
HKD2_k127_408439_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000000000000000000000000000000000000000000239 174.0
HKD2_k127_408439_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000002008 141.0
HKD2_k127_408439_6 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000003401 80.0
HKD2_k127_4097200_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.607e-300 932.0
HKD2_k127_4097200_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000007222 148.0
HKD2_k127_4097200_2 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000004707 135.0
HKD2_k127_4111728_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 2.946e-286 888.0
HKD2_k127_4111728_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.276e-215 679.0
HKD2_k127_4111728_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 509.0
HKD2_k127_4111728_3 Peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 468.0
HKD2_k127_4111728_4 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 318.0
HKD2_k127_4111728_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 302.0
HKD2_k127_4111728_6 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000004468 216.0
HKD2_k127_4111728_7 - - - - 0.00000000000000000000002363 103.0
HKD2_k127_4117445_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 8.061e-305 942.0
HKD2_k127_4117445_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 341.0
HKD2_k127_4117445_2 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004494 270.0
HKD2_k127_4117445_3 Cytochrome b K03887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000855 246.0
HKD2_k127_4117445_4 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000003204 202.0
HKD2_k127_4117445_5 Rieske [2Fe-2S] domain K03886 - - 0.000000000000000000000000004403 118.0
HKD2_k127_4117445_6 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000003025 119.0
HKD2_k127_4117445_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000007717 63.0
HKD2_k127_4117445_8 succinate dehydrogenase K00241,K00247 - - 0.0000000008085 64.0
HKD2_k127_4117445_9 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0003772 49.0
HKD2_k127_4139456_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 361.0
HKD2_k127_4139456_1 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 296.0
HKD2_k127_4156350_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 523.0
HKD2_k127_4156350_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 324.0
HKD2_k127_4156350_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001188 273.0
HKD2_k127_4156350_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000006071 223.0
HKD2_k127_4156350_4 G5 domain protein - - - 0.00000000000000000000000000000000305 145.0
HKD2_k127_4156350_5 PFAM glycoside hydrolase family 10 - - - 0.000000000000000000193 94.0
HKD2_k127_4165975_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 541.0
HKD2_k127_4165975_1 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 417.0
HKD2_k127_4165975_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 313.0
HKD2_k127_4165975_3 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000003546 186.0
HKD2_k127_425781_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 330.0
HKD2_k127_425781_1 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001092 285.0
HKD2_k127_425781_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000005557 195.0
HKD2_k127_425781_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000003396 143.0
HKD2_k127_4262196_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.418e-205 651.0
HKD2_k127_4262196_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 533.0
HKD2_k127_4262196_10 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000003757 149.0
HKD2_k127_4262196_11 Protein of unknown function (DUF1706) - - - 0.0000000000000000000000000000000001347 140.0
HKD2_k127_4262196_12 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.00000000000000000000000000001227 125.0
HKD2_k127_4262196_13 transcriptional regulator - - - 0.0000000000000000000000001138 114.0
HKD2_k127_4262196_14 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000000000000000004775 111.0
HKD2_k127_4262196_15 Phosphotransferase - - - 0.00000000000000000008913 100.0
HKD2_k127_4262196_16 Winged helix DNA-binding domain - - - 0.0000000000000000006303 89.0
HKD2_k127_4262196_17 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000006433 64.0
HKD2_k127_4262196_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 456.0
HKD2_k127_4262196_3 Thioredoxin reductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
HKD2_k127_4262196_4 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 299.0
HKD2_k127_4262196_5 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002882 263.0
HKD2_k127_4262196_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000001373 256.0
HKD2_k127_4262196_7 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000001601 229.0
HKD2_k127_4262196_8 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000002709 163.0
HKD2_k127_4262196_9 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000001837 150.0
HKD2_k127_4269798_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 7.623e-294 915.0
HKD2_k127_4269798_1 Glycogen debranching enzyme, glucanotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 441.0
HKD2_k127_4269798_10 Flavin containing amine oxidoreductase - - - 0.0000000000000000001276 103.0
HKD2_k127_4269798_11 response to abiotic stimulus K01971,K03086,K06867,K06886 GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006996,GO:0007010,GO:0007015,GO:0008092,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030029,GO:0030036,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044877,GO:0046983,GO:0051015,GO:0051259,GO:0065003,GO:0071840,GO:0097435 6.5.1.1 0.000000000000000007756 91.0
HKD2_k127_4269798_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009178 276.0
HKD2_k127_4269798_3 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001745 256.0
HKD2_k127_4269798_4 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000081 240.0
HKD2_k127_4269798_5 PFAM peptidase S58, DmpA - - - 0.00000000000000000000000000000000000000000000000000000000000001075 220.0
HKD2_k127_4269798_6 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000002745 220.0
HKD2_k127_4269798_7 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000007241 143.0
HKD2_k127_4269798_8 Pfam:DUF422 K08977 - 4.2.1.161 0.00000000000000000000000000000000002393 146.0
HKD2_k127_4269798_9 enzyme binding K00567,K07443 - 2.1.1.63 0.000000000000000000005728 97.0
HKD2_k127_4290456_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 498.0
HKD2_k127_4290456_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 375.0
HKD2_k127_4290456_3 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 296.0
HKD2_k127_4290456_4 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 281.0
HKD2_k127_4290456_5 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003283 266.0
HKD2_k127_4290456_7 DNA-binding transcription factor activity K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000531 183.0
HKD2_k127_4301408_0 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006217 267.0
HKD2_k127_4301408_1 - - - - 0.000000000000000000000000000000000000000000000003109 185.0
HKD2_k127_4301408_2 Protein of unknown function (DUF3052) - - - 0.0000000000000000000002983 102.0
HKD2_k127_4301408_3 Belongs to the UPF0250 family K09158 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000003218 87.0
HKD2_k127_4305443_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000102 217.0
HKD2_k127_4305443_1 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000003516 220.0
HKD2_k127_4305443_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000006518 178.0
HKD2_k127_4305443_3 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.000000000000000000000000000009792 123.0
HKD2_k127_4305443_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000759 122.0
HKD2_k127_4305443_5 TadE-like protein - - - 0.00000002241 62.0
HKD2_k127_4305443_6 domain, Protein - - - 0.00008138 53.0
HKD2_k127_4305443_7 PFAM TadE family protein - - - 0.0005231 44.0
HKD2_k127_4333550_0 Belongs to the peptidase S16 family - - - 3.113e-264 837.0
HKD2_k127_4333550_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.371e-213 676.0
HKD2_k127_4333550_10 COGs COG0601 ABC-type dipeptide oligopeptide nickel transport systems permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000007218 215.0
HKD2_k127_4333550_11 PFAM Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000009639 219.0
HKD2_k127_4333550_12 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000001523 206.0
HKD2_k127_4333550_13 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000001733 196.0
HKD2_k127_4333550_14 Psort location Cytoplasmic, score - - - 0.00000000000000000459 91.0
HKD2_k127_4333550_15 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.000000000000005082 76.0
HKD2_k127_4333550_16 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000582 77.0
HKD2_k127_4333550_17 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000007626 59.0
HKD2_k127_4333550_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 544.0
HKD2_k127_4333550_3 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 447.0
HKD2_k127_4333550_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 434.0
HKD2_k127_4333550_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 411.0
HKD2_k127_4333550_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 382.0
HKD2_k127_4333550_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 305.0
HKD2_k127_4333550_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 293.0
HKD2_k127_4333550_9 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001404 297.0
HKD2_k127_4404_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 605.0
HKD2_k127_4404_1 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 504.0
HKD2_k127_4404_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 340.0
HKD2_k127_4404_3 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000002417 199.0
HKD2_k127_4404_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000001506 184.0
HKD2_k127_4404_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000008231 166.0
HKD2_k127_4404_6 SnoaL-like domain - - - 0.0000000000000000000000000000000000000003565 152.0
HKD2_k127_4404_7 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000001342 93.0
HKD2_k127_4410622_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.305e-252 791.0
HKD2_k127_4410622_1 Molydopterin dinucleotide binding domain - - - 3.323e-220 704.0
HKD2_k127_4410622_10 Cytochrome c K02030,K17760,K19713 - 1.1.9.1,1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003795 286.0
HKD2_k127_4410622_11 PFAM cytochrome c oxidase, subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004585 266.0
HKD2_k127_4410622_12 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000003511 220.0
HKD2_k127_4410622_13 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000001112 220.0
HKD2_k127_4410622_14 PFAM ABC-2 type transporter K01992,K09690 - - 0.0000000000000000000000000000000000000000000000000001113 196.0
HKD2_k127_4410622_15 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000001953 169.0
HKD2_k127_4410622_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000002883 158.0
HKD2_k127_4410622_17 mitochondrial respiratory chain complex IV assembly K14998 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944 - 0.000000000000000000000000000000000000006456 155.0
HKD2_k127_4410622_18 SCO1/SenC K03619,K07152 GO:0003674,GO:0005048,GO:0005488,GO:0033218,GO:0042277 - 0.0000000000000000000000000000000000006529 153.0
HKD2_k127_4410622_19 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000000000000000000000000000000002128 151.0
HKD2_k127_4410622_2 PFAM Polysulphide reductase, NrfD K00185 - - 1.991e-205 648.0
HKD2_k127_4410622_20 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000005099 134.0
HKD2_k127_4410622_21 arylsulfatase activity - - - 0.000000000000000000000000007274 126.0
HKD2_k127_4410622_23 Glycosyl transferase family 2 - - - 0.000000000000000000000002138 121.0
HKD2_k127_4410622_24 PBS lyase HEAT-like repeat - - - 0.000000000000004681 82.0
HKD2_k127_4410622_3 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 360.0
HKD2_k127_4410622_4 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 336.0
HKD2_k127_4410622_5 Sodium/hydrogen exchanger family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 351.0
HKD2_k127_4410622_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 361.0
HKD2_k127_4410622_7 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 299.0
HKD2_k127_4410622_8 overlaps another CDS with the same product name K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 294.0
HKD2_k127_4410622_9 ABC transporter related K01990,K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000701 283.0
HKD2_k127_4410736_0 Acetamidase/Formamidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000001894 233.0
HKD2_k127_4410736_1 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000392 203.0
HKD2_k127_4410736_2 Phosphotransferase enzyme family K18844 - - 0.0000000000000000000000000000000000000000000009437 171.0
HKD2_k127_4426835_0 Serine carboxypeptidase - - - 1.912e-219 693.0
HKD2_k127_4426835_1 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 306.0
HKD2_k127_4426835_2 Glycosyltransferase family 28 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 294.0
HKD2_k127_4426835_4 DinB superfamily - - - 0.0000000000000001107 86.0
HKD2_k127_4426835_5 integral membrane protein K00728 - 2.4.1.109 0.000003473 58.0
HKD2_k127_4461484_0 Dehydrogenase E1 component K00615 - 2.2.1.1 5.313e-310 968.0
HKD2_k127_4461484_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 1.815e-229 729.0
HKD2_k127_4461484_2 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 369.0
HKD2_k127_4461484_3 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 331.0
HKD2_k127_4461484_4 PFAM PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004392 269.0
HKD2_k127_4461484_5 PFAM Roadblock LC7 family protein K07131 - - 0.000000000000000000000000000000000000000000004102 166.0
HKD2_k127_4486458_0 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000008972 236.0
HKD2_k127_4486458_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000001237 126.0
HKD2_k127_4486458_2 AAA ATPase domain K12132 - 2.7.11.1 0.00000000000000000000000000001002 125.0
HKD2_k127_4512892_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 2e-200 653.0
HKD2_k127_4512892_1 PFAM type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 573.0
HKD2_k127_4512892_10 chromosome segregation - - - 0.00000000000000000000000005457 113.0
HKD2_k127_4512892_11 - - - - 0.000000000000000001358 90.0
HKD2_k127_4512892_12 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000001989 83.0
HKD2_k127_4512892_2 GH3 auxin-responsive promoter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 490.0
HKD2_k127_4512892_3 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 434.0
HKD2_k127_4512892_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 313.0
HKD2_k127_4512892_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002861 248.0
HKD2_k127_4512892_6 Ferritin-like - - - 0.0000000000000000000000000000000000000000000000000000000000002013 220.0
HKD2_k127_4512892_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000006327 190.0
HKD2_k127_4512892_8 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000008476 169.0
HKD2_k127_4512892_9 Streptomycin adenylyltransferase K05593 - - 0.0000000000000000000000000000000005024 132.0
HKD2_k127_4555997_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 628.0
HKD2_k127_4555997_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 459.0
HKD2_k127_4555997_2 Rieske (2Fe-2S) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 318.0
HKD2_k127_4555997_3 PFAM Exonuclease, RNase T and DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001062 186.0
HKD2_k127_4555997_4 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000005111 142.0
HKD2_k127_4555997_5 acetyltransferase - - - 0.0000000000000000000000000002056 120.0
HKD2_k127_4555997_6 PspC domain - - - 0.0000000000000005378 79.0
HKD2_k127_4555997_7 DNA polymerase III, epsilon subunit and related 3'-5' K02342 - 2.7.7.7 0.000000000000003614 83.0
HKD2_k127_4555997_8 acetyltransferase - - - 0.0000000001492 66.0
HKD2_k127_4558611_0 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000001083 191.0
HKD2_k127_4558611_1 TadE-like protein - - - 0.000000002643 63.0
HKD2_k127_4558611_2 PFAM TadE family protein - - - 0.000000005532 68.0
HKD2_k127_4558611_3 - - - - 0.0001752 49.0
HKD2_k127_4592658_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1374.0
HKD2_k127_4592658_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 5.895e-230 722.0
HKD2_k127_4592658_10 Transglycosylase associated protein - - - 0.000000000000004509 77.0
HKD2_k127_4592658_11 CsbD-like - - - 0.000000000002538 68.0
HKD2_k127_4592658_2 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 356.0
HKD2_k127_4592658_3 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005303 265.0
HKD2_k127_4592658_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000691 239.0
HKD2_k127_4592658_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000314 206.0
HKD2_k127_4592658_6 - - - - 0.00000000000000000000000000000000000001519 151.0
HKD2_k127_4592658_7 PFAM HD domain - - - 0.000000000000000000000000006434 127.0
HKD2_k127_4592658_8 pfam cbs - - - 0.00000000000000000000000128 113.0
HKD2_k127_4592658_9 integral membrane protein - - - 0.00000000000000000002873 95.0
HKD2_k127_4605663_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 353.0
HKD2_k127_4605663_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 335.0
HKD2_k127_4605663_3 PFAM PfkB domain protein K16328 - 2.7.1.83 0.000000000000000000000000000000000000000000000001742 178.0
HKD2_k127_4605663_4 DNA-binding transcription factor activity - - - 0.0000000000000000000001998 107.0
HKD2_k127_4605663_5 Right handed beta helix region - - - 0.000000000000002478 87.0
HKD2_k127_4641382_0 NADH dehydrogenase K00335 - 1.6.5.3 4.408e-248 779.0
HKD2_k127_4641382_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 394.0
HKD2_k127_4641382_2 4Fe-4S binding domain K02572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001686 272.0
HKD2_k127_4641382_3 TIGRFAM reductive dehalogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001445 261.0
HKD2_k127_4641382_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003791 179.0
HKD2_k127_4641382_5 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000223 174.0
HKD2_k127_4641382_6 helix_turn_helix, Lux Regulon K02479,K07692 - - 0.00004571 52.0
HKD2_k127_4650447_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 3.376e-250 790.0
HKD2_k127_4650447_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 534.0
HKD2_k127_4650447_2 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 368.0
HKD2_k127_4650447_3 PFAM DRTGG domain protein K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 281.0
HKD2_k127_4690798_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1053.0
HKD2_k127_4690798_1 - - - - 0.00000001412 60.0
HKD2_k127_4694535_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.308e-245 781.0
HKD2_k127_4694535_1 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 5.899e-210 655.0
HKD2_k127_4694535_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000262 205.0
HKD2_k127_4694535_11 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000004374 181.0
HKD2_k127_4694535_2 DHH family K07462 - - 4.019e-201 652.0
HKD2_k127_4694535_3 PFAM ABC transporter K06020 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 572.0
HKD2_k127_4694535_4 DNA helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 497.0
HKD2_k127_4694535_5 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
HKD2_k127_4694535_6 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 318.0
HKD2_k127_4694535_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 315.0
HKD2_k127_4694535_8 DNA helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
HKD2_k127_4694535_9 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000001143 218.0
HKD2_k127_4732578_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.191e-225 715.0
HKD2_k127_4732578_1 PFAM Amidohydrolase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 561.0
HKD2_k127_4732578_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000004548 243.0
HKD2_k127_4732578_11 Putative neutral zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000000000001726 222.0
HKD2_k127_4732578_12 Coenzyme A transferase K01028,K01039 - 2.8.3.12,2.8.3.5 0.0000000000000000000000000000000000000000000000003142 185.0
HKD2_k127_4732578_13 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000003259 185.0
HKD2_k127_4732578_14 Haloacid dehalogenase-like hydrolase K07025,K18551 - - 0.000000000000000000000000000000000000000000000002823 180.0
HKD2_k127_4732578_15 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000000000004473 155.0
HKD2_k127_4732578_16 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000002166 153.0
HKD2_k127_4732578_17 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000002259 118.0
HKD2_k127_4732578_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000001377 98.0
HKD2_k127_4732578_19 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000009751 93.0
HKD2_k127_4732578_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 417.0
HKD2_k127_4732578_20 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000006559 81.0
HKD2_k127_4732578_21 Sortase family K07284 - 3.4.22.70 0.0000006142 62.0
HKD2_k127_4732578_3 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 363.0
HKD2_k127_4732578_4 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 358.0
HKD2_k127_4732578_5 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 357.0
HKD2_k127_4732578_6 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 303.0
HKD2_k127_4732578_7 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 291.0
HKD2_k127_4732578_8 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000371 269.0
HKD2_k127_4732578_9 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000196 255.0
HKD2_k127_473569_0 Heat shock 70 kDa protein K04043 - - 5.928e-320 989.0
HKD2_k127_473569_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 452.0
HKD2_k127_473569_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 396.0
HKD2_k127_473569_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000007092 172.0
HKD2_k127_473569_4 ribosomal protein - - - 0.0000000000000000000000000000000000000001896 153.0
HKD2_k127_473569_5 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000002691 80.0
HKD2_k127_475711_0 PFAM ABC transporter related K16786,K16787 - - 6.215e-222 700.0
HKD2_k127_475711_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 493.0
HKD2_k127_475711_10 ECF-type riboflavin transporter, S component K16924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001905 257.0
HKD2_k127_475711_11 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002453 252.0
HKD2_k127_475711_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000011 228.0
HKD2_k127_475711_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000005718 192.0
HKD2_k127_475711_14 Lysin motif - - - 0.00000000000000000000000000000000000000000000000009954 189.0
HKD2_k127_475711_15 Protein of unknown function (DUF2905) - - - 0.0000000000004594 71.0
HKD2_k127_475711_2 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 463.0
HKD2_k127_475711_3 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 383.0
HKD2_k127_475711_4 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 356.0
HKD2_k127_475711_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 364.0
HKD2_k127_475711_6 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 311.0
HKD2_k127_475711_7 tRNA processing K04075,K21947 - 2.8.1.15,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 287.0
HKD2_k127_475711_8 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000478 284.0
HKD2_k127_475711_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003263 272.0
HKD2_k127_4830883_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.543e-256 798.0
HKD2_k127_4830883_2 dnaJ homolog subfamily C member K19373 - - 0.0000000000002478 73.0
HKD2_k127_4844794_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.132e-263 833.0
HKD2_k127_4844794_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 2.894e-207 650.0
HKD2_k127_4844794_2 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 458.0
HKD2_k127_4844794_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
HKD2_k127_4844794_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 383.0
HKD2_k127_4844794_5 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002767 246.0
HKD2_k127_4844794_6 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0000000007865 68.0
HKD2_k127_4844794_7 Domain of unknown function (DUF4340) - - - 0.000297 51.0
HKD2_k127_4854932_0 ADP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 621.0
HKD2_k127_4854932_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 451.0
HKD2_k127_4854932_10 peroxiredoxin activity K03386,K03564,K16922 - 1.11.1.15 0.00000126 54.0
HKD2_k127_4854932_11 YCII-related domain - - - 0.000004304 54.0
HKD2_k127_4854932_2 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 432.0
HKD2_k127_4854932_3 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 370.0
HKD2_k127_4854932_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 320.0
HKD2_k127_4854932_5 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 323.0
HKD2_k127_4854932_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003343 240.0
HKD2_k127_4854932_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000172 121.0
HKD2_k127_4854932_8 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.00000000000000000000002935 109.0
HKD2_k127_4885349_0 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 521.0
HKD2_k127_4885349_1 Serine dehydrogenase proteinase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 369.0
HKD2_k127_4885349_2 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 353.0
HKD2_k127_4885349_3 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 310.0
HKD2_k127_4885349_4 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008757 264.0
HKD2_k127_4885349_5 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000006542 230.0
HKD2_k127_4885349_6 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000009636 169.0
HKD2_k127_4885349_7 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000001797 155.0
HKD2_k127_4893243_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2111.0
HKD2_k127_4893243_1 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 1.7e-259 837.0
HKD2_k127_4893243_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000006904 113.0
HKD2_k127_4893243_11 finger protein K16276 - - 0.0000000000000002326 87.0
HKD2_k127_4893243_2 PFAM ABC transporter related K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 417.0
HKD2_k127_4893243_3 extracellular solute-binding protein, family 3 K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 353.0
HKD2_k127_4893243_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 339.0
HKD2_k127_4893243_5 Binding-protein-dependent transport system inner membrane component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 327.0
HKD2_k127_4893243_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000284 285.0
HKD2_k127_4893243_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000006397 152.0
HKD2_k127_4893243_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000005902 124.0
HKD2_k127_4893243_9 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000001521 126.0
HKD2_k127_4898582_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.283e-265 829.0
HKD2_k127_4898582_1 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 529.0
HKD2_k127_4898582_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000007129 104.0
HKD2_k127_4898582_11 Transport permease protein K01992 - - 0.000000000000000001893 98.0
HKD2_k127_4898582_12 - - - - 0.000000000167 64.0
HKD2_k127_4898582_13 - - - - 0.0007044 46.0
HKD2_k127_4898582_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 368.0
HKD2_k127_4898582_3 in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 325.0
HKD2_k127_4898582_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001707 276.0
HKD2_k127_4898582_5 PFAM Diacylglycerol kinase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000003639 225.0
HKD2_k127_4898582_6 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000001817 183.0
HKD2_k127_4898582_7 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000003119 173.0
HKD2_k127_4898582_8 COG2076 Membrane transporters of cations and cationic drugs K03297,K11814 - - 0.00000000000000000000000000000003075 128.0
HKD2_k127_4898582_9 O-methyltransferase activity K00543,K13169 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008172,GO:0008757,GO:0009058,GO:0009059,GO:0009308,GO:0009309,GO:0009987,GO:0010467,GO:0010817,GO:0016740,GO:0016741,GO:0017096,GO:0017144,GO:0018130,GO:0019438,GO:0019538,GO:0030186,GO:0030187,GO:0032259,GO:0034641,GO:0034645,GO:0034754,GO:0042401,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046483,GO:0046983,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1905939,GO:1905940,GO:2000018,GO:2000019,GO:2000026,GO:2000241,GO:2000242 2.1.1.4 0.00000000000000000000000008844 119.0
HKD2_k127_4937216_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 534.0
HKD2_k127_4937216_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 441.0
HKD2_k127_4937216_10 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.00000000000000000000000000000001183 134.0
HKD2_k127_4937216_11 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.00000000000000000000000000006109 124.0
HKD2_k127_4937216_12 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000563 112.0
HKD2_k127_4937216_13 Large extracellular alpha-helical protein K06894,K08693 - 3.1.3.5,3.1.3.6,3.1.4.16 0.0000000000000000001583 103.0
HKD2_k127_4937216_14 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.0000000000000000003644 89.0
HKD2_k127_4937216_15 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000001988 100.0
HKD2_k127_4937216_16 - - - - 0.0001534 49.0
HKD2_k127_4937216_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 338.0
HKD2_k127_4937216_3 Methyltransferase domain K06983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 296.0
HKD2_k127_4937216_4 ECF transporter, substrate-specific component K16927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004401 284.0
HKD2_k127_4937216_5 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005677 283.0
HKD2_k127_4937216_6 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002182 260.0
HKD2_k127_4937216_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000000000000000004744 215.0
HKD2_k127_4937216_8 PFAM Pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000001448 188.0
HKD2_k127_4937216_9 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000001821 176.0
HKD2_k127_4995858_0 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 304.0
HKD2_k127_4995858_1 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.00000000000000000000000000000000000000009883 156.0
HKD2_k127_4995858_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000001149 156.0
HKD2_k127_4995858_3 PspC domain K03973 - - 0.0000000000001565 72.0
HKD2_k127_4995858_4 WD40 repeat-like protein - - - 0.0004933 52.0
HKD2_k127_5013767_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 9.713e-285 912.0
HKD2_k127_5013767_1 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 290.0
HKD2_k127_5013767_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000332 266.0
HKD2_k127_5013767_3 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000593 239.0
HKD2_k127_5013767_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000001526 226.0
HKD2_k127_5013767_5 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000001991 228.0
HKD2_k127_5013767_6 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000000000000592 171.0
HKD2_k127_5030094_0 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 441.0
HKD2_k127_5030094_1 -O-antigen K13009,K18814 - - 0.000000000000000000000000000000000000000003362 170.0
HKD2_k127_5030094_2 Signal peptidase K13280 - 3.4.21.89 0.000000001254 67.0
HKD2_k127_5030094_3 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000478 49.0
HKD2_k127_5045698_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000001352 180.0
HKD2_k127_5045698_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000001039 122.0
HKD2_k127_5045698_2 Probable molybdopterin binding domain - - - 0.0000000002913 61.0
HKD2_k127_5045698_3 TadE-like protein - - - 0.00000006159 60.0
HKD2_k127_5045698_4 TadE-like protein - - - 0.00000157 56.0
HKD2_k127_5045698_5 domain, Protein - - - 0.000004515 57.0
HKD2_k127_5047783_0 virulence factor implicated in the pathogenesis of mycobacterium tuberculosis at the level of intracellular survival, by the alteration of cell signaling events or by direct cytotoxicity catalytic activity a phosphatidylcholine H(2)O 1,2- diacylglycerol choline phosphate K01114 GO:0003674,GO:0003824,GO:0004620,GO:0004629,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006629,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009405,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0034480,GO:0035821,GO:0042578,GO:0044003,GO:0044238,GO:0044403,GO:0044419,GO:0044464,GO:0051701,GO:0051704,GO:0051817,GO:0052008,GO:0052043,GO:0052111,GO:0052185,GO:0052188,GO:0052368,GO:0071704,GO:0071944,GO:1901575 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000001985 241.0
HKD2_k127_5047783_1 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000001539 183.0
HKD2_k127_5047783_2 PFAM Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000008559 130.0
HKD2_k127_5047783_3 methyltransferase activity - - - 0.00000000000000000000000001723 111.0
HKD2_k127_5049176_0 PFAM glycosyl transferase, family 51 - - - 0.0 1238.0
HKD2_k127_5049176_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1065.0
HKD2_k127_5049176_10 ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003752 286.0
HKD2_k127_5049176_11 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000001363 253.0
HKD2_k127_5049176_12 succinylglutamate desuccinylase aspartoacylase K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003827 252.0
HKD2_k127_5049176_13 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006296 247.0
HKD2_k127_5049176_14 Hydrolase, alpha beta domain protein K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000273 238.0
HKD2_k127_5049176_15 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000001615 202.0
HKD2_k127_5049176_16 - - - - 0.000000000000000000000000000000000000000000000000000002823 194.0
HKD2_k127_5049176_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000003887 196.0
HKD2_k127_5049176_18 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000002637 191.0
HKD2_k127_5049176_19 - - - - 0.0000000000000000000000000000000000000000000000000005401 190.0
HKD2_k127_5049176_20 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000005228 182.0
HKD2_k127_5049176_21 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000003614 172.0
HKD2_k127_5049176_22 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000003892 170.0
HKD2_k127_5049176_23 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000001499 135.0
HKD2_k127_5049176_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 442.0
HKD2_k127_5049176_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 357.0
HKD2_k127_5049176_5 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 331.0
HKD2_k127_5049176_6 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 323.0
HKD2_k127_5049176_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 326.0
HKD2_k127_5049176_8 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 301.0
HKD2_k127_5049176_9 PFAM Thioredoxin domain K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 293.0
HKD2_k127_5049591_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 518.0
HKD2_k127_5049591_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005005 271.0
HKD2_k127_5049591_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000000000000000000000000000001199 123.0
HKD2_k127_5049591_3 cysteine-type peptidase activity - - - 0.00000000000001593 87.0
HKD2_k127_5049591_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000002125 55.0
HKD2_k127_5049591_5 trisaccharide binding K03556 - - 0.0005948 42.0
HKD2_k127_5117694_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 523.0
HKD2_k127_5117694_1 Tagatose 6 phosphate kinase K16371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 455.0
HKD2_k127_5117694_10 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000000001024 206.0
HKD2_k127_5117694_11 heat shock protein binding - - - 0.000000000000000000000000000000000000000002223 162.0
HKD2_k127_5117694_12 protein histidine kinase activity K03406 - - 0.00000000000000000004873 102.0
HKD2_k127_5117694_13 4Fe-4S dicluster domain - - - 0.0000000000001123 74.0
HKD2_k127_5117694_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 395.0
HKD2_k127_5117694_3 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 367.0
HKD2_k127_5117694_4 SIS domain K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 347.0
HKD2_k127_5117694_5 transmembrane transport K02025,K05814,K10118,K10237,K10241,K15771,K17235,K17242,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 340.0
HKD2_k127_5117694_6 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 329.0
HKD2_k127_5117694_7 DeoR C terminal sensor domain K02081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 294.0
HKD2_k127_5117694_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000003155 242.0
HKD2_k127_5117694_9 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000009564 218.0
HKD2_k127_5125909_0 Transketolase, pyrimidine binding domain - - - 3.006e-238 756.0
HKD2_k127_5125909_1 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000003592 155.0
HKD2_k127_5146050_0 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 520.0
HKD2_k127_5146050_1 Phosphoesterase or phosphohydrolase - - - 0.0000000002477 63.0
HKD2_k127_5151914_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1428.0
HKD2_k127_5151914_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1236.0
HKD2_k127_5151914_2 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 543.0
HKD2_k127_5151914_3 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002205 267.0
HKD2_k127_5151914_4 Transposase IS200 like - - - 0.0000000909 54.0
HKD2_k127_515584_0 Belongs to the thiolase family - - - 1.937e-198 625.0
HKD2_k127_515584_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 335.0
HKD2_k127_515584_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000003608 132.0
HKD2_k127_5170482_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 492.0
HKD2_k127_5170482_1 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 402.0
HKD2_k127_5179248_0 Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 0.0 1184.0
HKD2_k127_5179248_1 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0 1104.0
HKD2_k127_5179248_10 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000299 226.0
HKD2_k127_5179248_11 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
HKD2_k127_5179248_12 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000007344 209.0
HKD2_k127_5179248_13 GtrA-like protein - - - 0.00000000000000000000000000000000000000000000000001947 184.0
HKD2_k127_5179248_14 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000009634 122.0
HKD2_k127_5179248_15 Tetratricopeptide repeat - - - 0.000005806 53.0
HKD2_k127_5179248_2 beta-N-acetylhexosaminidase activity - - - 8.595e-218 692.0
HKD2_k127_5179248_3 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 551.0
HKD2_k127_5179248_4 SMART AAA ATPase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 470.0
HKD2_k127_5179248_5 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 426.0
HKD2_k127_5179248_6 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 416.0
HKD2_k127_5179248_7 pathogenesis K21471,K21687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 403.0
HKD2_k127_5179248_8 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 374.0
HKD2_k127_5179248_9 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 329.0
HKD2_k127_5184651_0 Aldo/keto reductase family - GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008076,GO:0008150,GO:0008152,GO:0009117,GO:0009898,GO:0009987,GO:0010959,GO:0012505,GO:0012506,GO:0015459,GO:0016020,GO:0016021,GO:0016192,GO:0016247,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019637,GO:0019897,GO:0019898,GO:0030141,GO:0030424,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031234,GO:0031410,GO:0031982,GO:0032879,GO:0032880,GO:0032940,GO:0032991,GO:0033267,GO:0034641,GO:0034702,GO:0034703,GO:0034705,GO:0034762,GO:0034765,GO:0035579,GO:0036230,GO:0042119,GO:0042581,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043266,GO:0043269,GO:0043299,GO:0043312,GO:0044224,GO:0044237,GO:0044238,GO:0044281,GO:0044304,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044463,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046496,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051179,GO:0051186,GO:0051234,GO:0055086,GO:0055114,GO:0060341,GO:0065007,GO:0065009,GO:0070820,GO:0070821,GO:0070995,GO:0071704,GO:0071944,GO:0072524,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098772,GO:0098796,GO:0098797,GO:0098805,GO:0099106,GO:0099503,GO:0120025,GO:0120038,GO:1901360,GO:1901379,GO:1901564,GO:1902495,GO:1903827,GO:1904062,GO:1990031,GO:1990351,GO:2000008 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 364.0
HKD2_k127_5184651_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000008421 193.0
HKD2_k127_5184651_2 PFAM Major Facilitator Superfamily K08223 - - 0.00000000000000001829 91.0
HKD2_k127_5202705_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 358.0
HKD2_k127_5202705_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000009583 210.0
HKD2_k127_5202705_2 Domain of unknown function (DUF4440) - - - 0.0000000000000000001413 96.0
HKD2_k127_5202705_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000001905 74.0
HKD2_k127_5204405_0 PHP domain protein K02347 - - 5.525e-204 650.0
HKD2_k127_5204405_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000002286 261.0
HKD2_k127_5204405_2 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002097 250.0
HKD2_k127_5204405_3 DMT(Drug metabolite transporter) superfamily permease - - - 0.00000000000000000000000000000000000000000000000000000000000899 218.0
HKD2_k127_521591_0 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 514.0
HKD2_k127_521591_1 ABC transporter, substratebinding protein K10232 - - 0.0000000000000000000000000000000000000000000000000000002266 213.0
HKD2_k127_521591_2 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000003538 176.0
HKD2_k127_521591_3 COG1175 ABC-type sugar transport systems permease components K10233 - - 0.00000000000000000000000000000000000001768 148.0
HKD2_k127_521591_4 coenzyme F420 binding - - - 0.00000000000000000000000000009708 123.0
HKD2_k127_5217534_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K16216 - 1.1.1.320 0.000000000000000000000000000000000000000000000000000000001041 209.0
HKD2_k127_5217534_1 -acetyltransferase - - - 0.000000000000000000000000000000000008625 147.0
HKD2_k127_5217534_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000004865 140.0
HKD2_k127_5217534_3 -acetyltransferase K03828,K17840 - 2.3.1.59 0.00000000000000000000000000000004303 135.0
HKD2_k127_5217534_4 Dimerisation domain - - - 0.00000000000000000000000000002282 130.0
HKD2_k127_5217534_5 EthD domain - - - 0.0000000000000000000000001039 110.0
HKD2_k127_5217534_6 NB-ARC domain - - - 0.00000000000000000000001513 106.0
HKD2_k127_5217534_7 O-methyltransferase - - - 0.00000000000000000002407 102.0
HKD2_k127_5217534_9 Luciferase-like monooxygenase - - - 0.0000006857 53.0
HKD2_k127_5221179_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1177.0
HKD2_k127_5221179_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 505.0
HKD2_k127_5221179_2 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 473.0
HKD2_k127_5221179_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 434.0
HKD2_k127_5221179_4 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 332.0
HKD2_k127_5221179_5 CAAX protease self-immunity - - - 0.00000000000000000000000000000001273 136.0
HKD2_k127_5221179_6 domain, Protein - - - 0.0000000000000000000000000000005046 128.0
HKD2_k127_5221179_7 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000068 129.0
HKD2_k127_5222426_0 penicillin amidase K01434 - 3.5.1.11 2.286e-319 998.0
HKD2_k127_5222426_1 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 518.0
HKD2_k127_5222426_11 - - - - 0.0000000000000000000000000000000000000000002372 170.0
HKD2_k127_5222426_12 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000007607 139.0
HKD2_k127_5222426_13 - - - - 0.000000000000000000000000000000003206 130.0
HKD2_k127_5222426_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000003611 126.0
HKD2_k127_5222426_15 chromate transporter K07240 - - 0.000000000000000000000000000005357 126.0
HKD2_k127_5222426_16 - - - - 0.0000000000000000000000000001266 125.0
HKD2_k127_5222426_17 Phospholipase_D-nuclease N-terminal - - - 0.000000000000004616 76.0
HKD2_k127_5222426_2 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 507.0
HKD2_k127_5222426_3 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 467.0
HKD2_k127_5222426_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 464.0
HKD2_k127_5222426_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 405.0
HKD2_k127_5222426_6 HhH-GPD family K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 377.0
HKD2_k127_5222426_7 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 309.0
HKD2_k127_5222426_8 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 312.0
HKD2_k127_5222426_9 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 301.0
HKD2_k127_5222965_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.447e-239 747.0
HKD2_k127_5222965_1 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000005011 141.0
HKD2_k127_5222965_2 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000734 139.0
HKD2_k127_5222965_3 PFAM Forkhead-associated protein - - - 0.0000000000000000014 95.0
HKD2_k127_5222965_4 - - - - 0.000000000004912 76.0
HKD2_k127_5229378_0 (ABC) transporter K06147 - - 4.213e-237 750.0
HKD2_k127_5229378_1 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 591.0
HKD2_k127_5229378_10 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000001357 211.0
HKD2_k127_5229378_11 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000002573 210.0
HKD2_k127_5229378_12 protein domain associated with K03595,K06883,K06946 - - 0.0000000000000000000000000000000000000000000000000002629 201.0
HKD2_k127_5229378_13 LysM domain K02020 - - 0.0000000000000000000000000000000000000000001309 169.0
HKD2_k127_5229378_14 - - - - 0.00000000000000000000000000000000000000001323 159.0
HKD2_k127_5229378_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001189 154.0
HKD2_k127_5229378_16 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000003544 146.0
HKD2_k127_5229378_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000001673 139.0
HKD2_k127_5229378_18 PKD domain containing protein - - - 0.00000000000000000000000225 119.0
HKD2_k127_5229378_2 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 499.0
HKD2_k127_5229378_20 PFAM Forkhead-associated - - - 0.0000000000003162 79.0
HKD2_k127_5229378_21 Conserved repeat domain - - - 0.00000000004625 73.0
HKD2_k127_5229378_22 WD40 domain protein beta Propeller - - - 0.000000006823 68.0
HKD2_k127_5229378_23 transcriptional - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00002311 52.0
HKD2_k127_5229378_24 peptidyl-tyrosine sulfation - - - 0.00006585 56.0
HKD2_k127_5229378_25 Involved in the tonB-independent uptake of proteins - - - 0.0001612 54.0
HKD2_k127_5229378_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 452.0
HKD2_k127_5229378_4 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 433.0
HKD2_k127_5229378_5 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 380.0
HKD2_k127_5229378_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 344.0
HKD2_k127_5229378_7 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 327.0
HKD2_k127_5229378_8 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
HKD2_k127_5229378_9 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002273 261.0
HKD2_k127_5241114_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 3.506e-310 963.0
HKD2_k127_5241114_1 Histidine kinase K07646 - 2.7.13.3 4.463e-293 924.0
HKD2_k127_5241114_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 376.0
HKD2_k127_5241114_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000003124 257.0
HKD2_k127_5241114_4 PFAM Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000009834 86.0
HKD2_k127_5245716_0 PFAM Glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 312.0
HKD2_k127_5245716_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000002212 175.0
HKD2_k127_5245716_2 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000000000000001984 76.0
HKD2_k127_5245716_3 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 0.000308 49.0
HKD2_k127_5285705_0 Aromatic amino acid lyase K01745 - 4.3.1.3 4.123e-259 805.0
HKD2_k127_5285705_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.646e-199 638.0
HKD2_k127_5285705_2 Peptidase family M28 K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 333.0
HKD2_k127_5285705_3 regulation of single-species biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000006079 229.0
HKD2_k127_5285705_4 Thiamine-binding protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000002246 154.0
HKD2_k127_5285705_5 4Fe-4S binding domain - - - 0.0000000000000000000000000000000002047 136.0
HKD2_k127_5285705_6 PFAM helix-turn-helix- domain containing protein, AraC type K13653 - - 0.0000000000000000000000000001822 121.0
HKD2_k127_5285705_7 membrane - - - 0.00001147 49.0
HKD2_k127_5285705_8 ThiS family - - - 0.0002645 47.0
HKD2_k127_5291660_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 7.419e-265 833.0
HKD2_k127_5291660_1 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 417.0
HKD2_k127_5291660_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 383.0
HKD2_k127_5291660_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 366.0
HKD2_k127_5291660_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 366.0
HKD2_k127_5291660_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 345.0
HKD2_k127_5291660_6 lipid binding - - - 0.00000000000000000000000000000000000000000000000000000000007284 213.0
HKD2_k127_5291660_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000007949 193.0
HKD2_k127_5291660_8 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000000000000001144 129.0
HKD2_k127_5291660_9 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000008757 102.0
HKD2_k127_5314137_0 Histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 401.0
HKD2_k127_5314137_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001559 298.0
HKD2_k127_5314137_2 response regulator K02479,K07695 GO:0001666,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006950,GO:0008150,GO:0009405,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010565,GO:0010604,GO:0010628,GO:0016020,GO:0018995,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0022611,GO:0030312,GO:0030430,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032502,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0036293,GO:0043656,GO:0043657,GO:0044174,GO:0044215,GO:0044216,GO:0044217,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0070482,GO:0071944,GO:0072493,GO:0080090,GO:0080134,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1902882,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003148 266.0
HKD2_k127_5314137_3 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000752 241.0
HKD2_k127_5314137_4 PFAM DoxX family protein K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000004262 205.0
HKD2_k127_5314137_5 cellulase activity - - - 0.0000005147 63.0
HKD2_k127_5319741_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 602.0
HKD2_k127_5319741_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 240.0
HKD2_k127_5319741_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000002018 198.0
HKD2_k127_5319741_3 - - - - 0.00000000000000000000000000000000000002139 151.0
HKD2_k127_5319741_4 TIGRFAM MoaD family protein K03636 - - 0.0000000000001938 73.0
HKD2_k127_5344565_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 341.0
HKD2_k127_5344565_1 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000004812 186.0
HKD2_k127_5344565_2 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000002933 152.0
HKD2_k127_5344565_3 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000000000004361 79.0
HKD2_k127_5358345_0 thiamine transport K02063 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005701 539.0
HKD2_k127_5358345_1 Orotidine-5-phosphate decarboxylase orotate phosphoribosyltransferase K01591,K13421 - 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 461.0
HKD2_k127_5358345_10 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000000002004 183.0
HKD2_k127_5358345_11 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000000002358 178.0
HKD2_k127_5358345_12 - - - - 0.0000000000103 71.0
HKD2_k127_5358345_13 metal ion binding. It is involved in the biological process described with 'de novo' pyrimidine nucleobase biosynthetic process K11540 GO:0000050,GO:0000052,GO:0000166,GO:0001882,GO:0001884,GO:0002119,GO:0002134,GO:0002164,GO:0003674,GO:0003824,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0004672,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006228,GO:0006464,GO:0006468,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007275,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009605,GO:0009653,GO:0009719,GO:0009725,GO:0009791,GO:0009887,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0016053,GO:0016301,GO:0016310,GO:0016363,GO:0016597,GO:0016740,GO:0016741,GO:0016743,GO:0016772,GO:0016773,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0017144,GO:0018107,GO:0018130,GO:0018193,GO:0018210,GO:0019103,GO:0019240,GO:0019438,GO:0019538,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0019899,GO:0022612,GO:0030424,GO:0030554,GO:0031406,GO:0031667,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0032868,GO:0032991,GO:0033267,GO:0034399,GO:0034404,GO:0034641,GO:0034654,GO:0035295,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0042221,GO:0042455,GO:0042594,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043195,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043434,GO:0043436,GO:0043603,GO:0043604,GO:0043679,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044463,GO:0044464,GO:0045202,GO:0046051,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046394,GO:0046483,GO:0046777,GO:0046872,GO:0046914,GO:0048513,GO:0048565,GO:0048731,GO:0048732,GO:0048856,GO:0050896,GO:0055086,GO:0055123,GO:0060465,GO:0070013,GO:0070335,GO:0070406,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:0097458,GO:0098793,GO:0120025,GO:0120038,GO:0140096,GO:0150034,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901652,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1905905 2.1.3.2,3.5.2.3,6.3.5.5 0.00000002815 55.0
HKD2_k127_5358345_14 PFAM response regulator receiver K07657,K07664 - - 0.0000004094 57.0
HKD2_k127_5358345_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 407.0
HKD2_k127_5358345_3 Bacterial extracellular solute-binding protein K02064 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 379.0
HKD2_k127_5358345_4 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 333.0
HKD2_k127_5358345_5 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
HKD2_k127_5358345_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 322.0
HKD2_k127_5358345_7 TIGRFAM small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 302.0
HKD2_k127_5358345_8 TOBE domain K02062,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 300.0
HKD2_k127_5358345_9 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000000000127 234.0
HKD2_k127_5375691_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.684e-242 760.0
HKD2_k127_5375691_1 FAD linked oxidases, C-terminal domain - - - 6.598e-228 739.0
HKD2_k127_5375691_10 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006787 278.0
HKD2_k127_5375691_11 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000001357 232.0
HKD2_k127_5375691_12 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K04075,K15780 GO:0003674,GO:0003824,GO:0004422,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0052657,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8,6.3.4.19 0.0000000000000000000000000000000000000000000000000002051 190.0
HKD2_k127_5375691_13 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000000000000008768 118.0
HKD2_k127_5375691_14 - - - - 0.000267 45.0
HKD2_k127_5375691_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 598.0
HKD2_k127_5375691_3 Stage II sporulation E family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 545.0
HKD2_k127_5375691_4 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 512.0
HKD2_k127_5375691_5 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 439.0
HKD2_k127_5375691_6 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 408.0
HKD2_k127_5375691_7 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 406.0
HKD2_k127_5375691_8 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 360.0
HKD2_k127_5375691_9 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 315.0
HKD2_k127_5390676_0 PFAM metal-dependent phosphohydrolase HD sub domain K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 287.0
HKD2_k127_5390676_1 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000003137 101.0
HKD2_k127_5390676_3 - K09712,K14475 - - 0.000000000000002984 83.0
HKD2_k127_5397281_0 Cation transporter/ATPase, N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 556.0
HKD2_k127_5397281_1 aminopeptidase activity K01179,K01269 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 501.0
HKD2_k127_5397281_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000002426 236.0
HKD2_k127_5397281_11 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000001835 224.0
HKD2_k127_5397281_12 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000008827 169.0
HKD2_k127_5397281_13 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000006732 144.0
HKD2_k127_5397281_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000001732 123.0
HKD2_k127_5397281_15 amino acid - - - 0.00000000000000002123 96.0
HKD2_k127_5397281_17 amino acid - - - 0.000000004828 69.0
HKD2_k127_5397281_18 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0000009881 50.0
HKD2_k127_5397281_2 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 381.0
HKD2_k127_5397281_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 327.0
HKD2_k127_5397281_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 298.0
HKD2_k127_5397281_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002349 277.0
HKD2_k127_5397281_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001717 275.0
HKD2_k127_5397281_7 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001949 262.0
HKD2_k127_5397281_8 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001446 267.0
HKD2_k127_5397281_9 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006514 246.0
HKD2_k127_5410731_0 lysyltransferase activity K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.0000000000000000000000000000000000000000000000000000000003452 217.0
HKD2_k127_5410731_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000004048 205.0
HKD2_k127_5410731_2 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000001642 140.0
HKD2_k127_5417621_0 Alpha amylase, catalytic domain - - - 0.0 1391.0
HKD2_k127_5417621_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 2.899e-225 707.0
HKD2_k127_5417621_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 552.0
HKD2_k127_5417621_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 464.0
HKD2_k127_5417621_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 408.0
HKD2_k127_5417621_5 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 393.0
HKD2_k127_5417621_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 363.0
HKD2_k127_5417621_7 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001045 226.0
HKD2_k127_5417621_8 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000006112 187.0
HKD2_k127_5417621_9 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000004835 164.0
HKD2_k127_5426964_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 3.667e-262 812.0
HKD2_k127_5426964_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 597.0
HKD2_k127_5426964_2 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 573.0
HKD2_k127_5426964_3 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 411.0
HKD2_k127_5426964_4 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002524 252.0
HKD2_k127_5426964_5 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000000006809 170.0
HKD2_k127_5426964_6 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000001026 149.0
HKD2_k127_5426964_7 Pfam:DUF59 - - - 0.0000000000000000000000000000000002254 134.0
HKD2_k127_5442697_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.895e-227 735.0
HKD2_k127_5442697_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.04e-213 669.0
HKD2_k127_5442697_2 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 589.0
HKD2_k127_5442697_4 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 343.0
HKD2_k127_5442697_5 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000009469 219.0
HKD2_k127_5442697_6 PFAM OsmC family protein K07397 - - 0.0000000000000000000000000000000000000000000000001201 182.0
HKD2_k127_5442697_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000003141 124.0
HKD2_k127_5442697_9 sigma-70 region 2 domain protein K03088 - - 0.00000000000000004315 81.0
HKD2_k127_5450227_0 AAA domain - - - 0.0000000000000005499 89.0
HKD2_k127_5450227_1 - - - - 0.000000000000006585 78.0
HKD2_k127_5450227_2 Phage terminase, small subunit - - - 0.000002003 55.0
HKD2_k127_5450227_3 DNA excision - - - 0.00009641 49.0
HKD2_k127_5486631_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 573.0
HKD2_k127_5486631_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 406.0
HKD2_k127_5486631_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002198 208.0
HKD2_k127_5486631_3 - - - - 0.0000000000000000000000000000000000008607 154.0
HKD2_k127_5486631_4 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000008948 145.0
HKD2_k127_5522962_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 471.0
HKD2_k127_5522962_1 Cys/Met metabolism PLP-dependent enzyme K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 454.0
HKD2_k127_5522962_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 287.0
HKD2_k127_5527240_0 PFAM NHL repeat containing protein - - - 0.0 1100.0
HKD2_k127_5527240_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.707e-229 716.0
HKD2_k127_5527240_10 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 418.0
HKD2_k127_5527240_11 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 407.0
HKD2_k127_5527240_12 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 385.0
HKD2_k127_5527240_13 Domain of unknown function (DUF4032) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 370.0
HKD2_k127_5527240_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 362.0
HKD2_k127_5527240_15 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 335.0
HKD2_k127_5527240_16 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
HKD2_k127_5527240_17 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 301.0
HKD2_k127_5527240_18 Kelch repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 302.0
HKD2_k127_5527240_19 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 299.0
HKD2_k127_5527240_2 Participates in both transcription termination and antitermination K02600 - - 5.345e-219 697.0
HKD2_k127_5527240_20 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 292.0
HKD2_k127_5527240_21 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003028 284.0
HKD2_k127_5527240_22 PFAM Diacylglycerol kinase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003034 269.0
HKD2_k127_5527240_23 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000005272 192.0
HKD2_k127_5527240_24 Acyl-transferase K00655,K00945 - 2.3.1.51,2.7.4.25 0.00000000000000000000000000000000000000000000000001269 188.0
HKD2_k127_5527240_25 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000778 162.0
HKD2_k127_5527240_26 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000001793 145.0
HKD2_k127_5527240_27 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000000001459 131.0
HKD2_k127_5527240_28 Membrane - - - 0.0000000000000000000000000000004637 139.0
HKD2_k127_5527240_29 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000001171 97.0
HKD2_k127_5527240_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.711e-200 641.0
HKD2_k127_5527240_30 - - - - 0.000000000000005221 88.0
HKD2_k127_5527240_31 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000008141 70.0
HKD2_k127_5527240_32 amino acid K03294 - - 0.00001152 56.0
HKD2_k127_5527240_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 577.0
HKD2_k127_5527240_5 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 574.0
HKD2_k127_5527240_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 485.0
HKD2_k127_5527240_7 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 491.0
HKD2_k127_5527240_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 461.0
HKD2_k127_5527240_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 414.0
HKD2_k127_55343_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0 1363.0
HKD2_k127_55343_1 exo-alpha-(2->6)-sialidase activity - - - 1.551e-235 742.0
HKD2_k127_55343_2 PFAM peptidase S1 and S6, chymotrypsin Hap K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 312.0
HKD2_k127_55343_3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001902 246.0
HKD2_k127_55343_4 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000000006076 214.0
HKD2_k127_55343_5 Cupin domain - - - 0.0000000000000000000000000000000000000001583 153.0
HKD2_k127_55343_6 Phosphomannose isomerase type I K01809,K01840 - 5.3.1.8,5.4.2.8 0.00000000000000000000000000001037 133.0
HKD2_k127_55343_7 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000624 84.0
HKD2_k127_5542028_0 PFAM type II secretion system protein E K02283 - - 3.312e-236 737.0
HKD2_k127_5542028_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 478.0
HKD2_k127_5542028_10 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000004301 167.0
HKD2_k127_5542028_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000001002 115.0
HKD2_k127_5542028_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000006666 112.0
HKD2_k127_5542028_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.00000000000000000000000004205 111.0
HKD2_k127_5542028_14 PFAM Flp Fap pilin component K02651 - - 0.000000007668 58.0
HKD2_k127_5542028_16 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000003556 57.0
HKD2_k127_5542028_2 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
HKD2_k127_5542028_3 PFAM type II secretion system protein K12510 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 330.0
HKD2_k127_5542028_4 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007077 288.0
HKD2_k127_5542028_5 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000006208 248.0
HKD2_k127_5542028_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000000007217 236.0
HKD2_k127_5542028_7 Flp pilus assembly protein CpaB K02279 - - 0.0000000000000000000000000000000000000000000000000000000000000000005358 243.0
HKD2_k127_5542028_8 competence protein - - - 0.000000000000000000000000000000000000000000000000000000000004122 216.0
HKD2_k127_5542028_9 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000008714 206.0
HKD2_k127_5548968_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 479.0
HKD2_k127_5548968_1 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 392.0
HKD2_k127_5548968_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 319.0
HKD2_k127_5548968_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 320.0
HKD2_k127_5548968_4 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000001151 193.0
HKD2_k127_5548968_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000001343 173.0
HKD2_k127_5548968_7 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000001796 106.0
HKD2_k127_563812_0 Short-chain dehydrogenase reductase SDR - - - 3.334e-233 737.0
HKD2_k127_563812_1 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 503.0
HKD2_k127_563812_10 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000645 162.0
HKD2_k127_563812_11 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000003561 148.0
HKD2_k127_563812_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000000000004049 134.0
HKD2_k127_563812_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000000001503 132.0
HKD2_k127_563812_2 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 456.0
HKD2_k127_563812_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 439.0
HKD2_k127_563812_4 1-aminocyclopropane-1-carboxylate deaminase K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 392.0
HKD2_k127_563812_5 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 377.0
HKD2_k127_563812_6 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 363.0
HKD2_k127_563812_7 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 344.0
HKD2_k127_563812_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 328.0
HKD2_k127_563812_9 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 339.0
HKD2_k127_5680504_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1117.0
HKD2_k127_5680504_1 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 579.0
HKD2_k127_5680504_2 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 444.0
HKD2_k127_5680504_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001859 276.0
HKD2_k127_5680504_4 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000904 243.0
HKD2_k127_5680504_5 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000367 224.0
HKD2_k127_5680504_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000001022 161.0
HKD2_k127_5680504_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000001545 162.0
HKD2_k127_5723497_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1184.0
HKD2_k127_5723497_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 9.189e-314 970.0
HKD2_k127_5723497_10 Dehydrogenase E1 component K21416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001037 284.0
HKD2_k127_5723497_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009809 264.0
HKD2_k127_5723497_12 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001898 215.0
HKD2_k127_5723497_13 PFAM RNA binding S1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000009671 217.0
HKD2_k127_5723497_14 spore germination K03298 - - 0.00000000000000000000000000000000000000000000000000000000002157 215.0
HKD2_k127_5723497_15 - - - - 0.00000000000000000000000000000000000000002587 156.0
HKD2_k127_5723497_16 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000002332 154.0
HKD2_k127_5723497_17 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000009055 137.0
HKD2_k127_5723497_19 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000002605 120.0
HKD2_k127_5723497_2 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 3.264e-199 633.0
HKD2_k127_5723497_20 response regulator K03413,K07719 - - 0.000000000000000000000001192 107.0
HKD2_k127_5723497_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 619.0
HKD2_k127_5723497_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 541.0
HKD2_k127_5723497_5 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 503.0
HKD2_k127_5723497_6 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 428.0
HKD2_k127_5723497_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 392.0
HKD2_k127_5723497_8 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 386.0
HKD2_k127_5723497_9 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 370.0
HKD2_k127_585218_0 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 310.0
HKD2_k127_585218_1 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000198 278.0
HKD2_k127_585218_2 arsonoacetate metabolic process K07755 - 2.1.1.137 0.00000000002068 73.0
HKD2_k127_585218_3 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0003898 47.0
HKD2_k127_5894992_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1116.0
HKD2_k127_5894992_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 3.028e-207 659.0
HKD2_k127_5894992_10 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000002101 88.0
HKD2_k127_5894992_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.000003126 53.0
HKD2_k127_5894992_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 347.0
HKD2_k127_5894992_3 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 305.0
HKD2_k127_5894992_4 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 284.0
HKD2_k127_5894992_5 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000258 270.0
HKD2_k127_5894992_6 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000000008591 210.0
HKD2_k127_5894992_7 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000006938 188.0
HKD2_k127_5894992_8 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000764 156.0
HKD2_k127_5903504_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1268.0
HKD2_k127_5903504_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 609.0
HKD2_k127_5903504_10 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 411.0
HKD2_k127_5903504_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 412.0
HKD2_k127_5903504_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 398.0
HKD2_k127_5903504_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 391.0
HKD2_k127_5903504_14 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 376.0
HKD2_k127_5903504_15 PFAM deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 327.0
HKD2_k127_5903504_16 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 331.0
HKD2_k127_5903504_17 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 325.0
HKD2_k127_5903504_18 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 286.0
HKD2_k127_5903504_19 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000009565 246.0
HKD2_k127_5903504_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 586.0
HKD2_k127_5903504_20 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000001865 231.0
HKD2_k127_5903504_22 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000000000000000000000000000000000002063 184.0
HKD2_k127_5903504_23 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000001358 151.0
HKD2_k127_5903504_24 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000004191 142.0
HKD2_k127_5903504_25 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000000000000002953 149.0
HKD2_k127_5903504_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000001681 124.0
HKD2_k127_5903504_27 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000003711 92.0
HKD2_k127_5903504_28 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000005769 79.0
HKD2_k127_5903504_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 585.0
HKD2_k127_5903504_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 537.0
HKD2_k127_5903504_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 529.0
HKD2_k127_5903504_6 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 535.0
HKD2_k127_5903504_7 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 467.0
HKD2_k127_5903504_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 452.0
HKD2_k127_5903504_9 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 438.0
HKD2_k127_5927327_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000478 188.0
HKD2_k127_5927327_1 Alpha beta superfamily - - - 0.000000000000000000000000004561 118.0
HKD2_k127_5951675_0 transcriptional regulator K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 534.0
HKD2_k127_5951675_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 362.0
HKD2_k127_5951675_10 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000009147 161.0
HKD2_k127_5951675_11 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.000000000000000000000000000000000001422 140.0
HKD2_k127_5951675_12 GNAT acetyltransferase - - - 0.00000000000000000000000000001165 129.0
HKD2_k127_5951675_13 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000001098 119.0
HKD2_k127_5951675_14 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.0000000000000000000000001862 116.0
HKD2_k127_5951675_15 - - - - 0.000000000000000005501 85.0
HKD2_k127_5951675_16 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000001318 71.0
HKD2_k127_5951675_17 2-phosphoglycerate kinase K05715 - - 0.00000006841 62.0
HKD2_k127_5951675_18 DNA integration - - - 0.0001124 47.0
HKD2_k127_5951675_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 346.0
HKD2_k127_5951675_3 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 295.0
HKD2_k127_5951675_4 PFAM Beta-lactamase K18988 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 299.0
HKD2_k127_5951675_5 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004342 243.0
HKD2_k127_5951675_6 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000002246 230.0
HKD2_k127_5951675_7 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000001415 200.0
HKD2_k127_5951675_8 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000006931 192.0
HKD2_k127_5951675_9 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000001115 194.0
HKD2_k127_5952564_0 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000001014 225.0
HKD2_k127_5952564_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000004519 185.0
HKD2_k127_5952564_2 TAP-like protein - - - 0.00000000000000000000000000792 115.0
HKD2_k127_6012322_0 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 315.0
HKD2_k127_6012322_1 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 313.0
HKD2_k127_6012322_2 isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000002437 135.0
HKD2_k127_6012322_3 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000002761 113.0
HKD2_k127_6012322_4 ubiE/COQ5 methyltransferase family - - - 0.000000008146 65.0
HKD2_k127_609136_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.325e-304 955.0
HKD2_k127_609136_1 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 458.0
HKD2_k127_609136_2 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 317.0
HKD2_k127_609136_3 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007552 246.0
HKD2_k127_609136_4 GrpB protein - - - 0.000000000000000000000000000000000000003711 153.0
HKD2_k127_609136_6 - - - - 0.0004837 51.0
HKD2_k127_6129106_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.004e-220 692.0
HKD2_k127_6129106_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
HKD2_k127_6129106_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
HKD2_k127_6129106_3 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000003802 138.0
HKD2_k127_6179301_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 530.0
HKD2_k127_6179301_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 308.0
HKD2_k127_6179301_2 PFAM amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 292.0
HKD2_k127_6179301_3 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004182 275.0
HKD2_k127_6179301_4 IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000006276 194.0
HKD2_k127_6179301_5 Copper amine oxidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000007807 192.0
HKD2_k127_6200222_0 PFAM peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 539.0
HKD2_k127_6200222_1 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
HKD2_k127_6200222_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001443 228.0
HKD2_k127_6200222_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000004581 186.0
HKD2_k127_6203483_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 466.0
HKD2_k127_6203483_1 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002935 279.0
HKD2_k127_6203483_2 PFAM peptidase S58, DmpA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
HKD2_k127_6203483_3 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000001364 184.0
HKD2_k127_6203483_4 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000002064 109.0
HKD2_k127_6203483_5 gas vesicle protein - - - 0.000001559 53.0
HKD2_k127_6241140_0 PFAM glycoside hydrolase family 35 K12308 - 3.2.1.23 6.01e-314 979.0
HKD2_k127_6241140_1 alginic acid biosynthetic process - - - 1.148e-264 834.0
HKD2_k127_6241140_2 Putative glucoamylase - - - 2.505e-200 634.0
HKD2_k127_6241140_3 Putative glucoamylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 559.0
HKD2_k127_6241140_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 420.0
HKD2_k127_6241140_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 401.0
HKD2_k127_6241140_6 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 385.0
HKD2_k127_6241140_7 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000111 235.0
HKD2_k127_6241140_8 purine nucleotide biosynthetic process K02529 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042802,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000007427 81.0
HKD2_k127_6252792_0 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001487 265.0
HKD2_k127_6252792_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000009573 237.0
HKD2_k127_6252792_2 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000005826 192.0
HKD2_k127_6252792_3 phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000005792 172.0
HKD2_k127_6252792_4 DNA-binding transcription factor activity K21903 - - 0.00000000000000000007185 92.0
HKD2_k127_6252792_5 Phosphodiester glycosidase - - - 0.00000000000000001071 97.0
HKD2_k127_6252792_6 o-methyltransferase - - - 0.00000000000000001284 86.0
HKD2_k127_6252792_7 O-methyltransferase - - - 0.00000004596 56.0
HKD2_k127_6275910_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 524.0
HKD2_k127_6275910_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009712 263.0
HKD2_k127_6275910_2 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 0.000000000000000004149 85.0
HKD2_k127_6275910_3 - - - - 0.00000002723 62.0
HKD2_k127_6366767_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001299 248.0
HKD2_k127_6366767_1 methyltransferase K21459 - 2.1.1.301 0.00000000000000000000000008269 117.0
HKD2_k127_6366767_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000129 93.0
HKD2_k127_6366825_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 581.0
HKD2_k127_6366825_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005567 282.0
HKD2_k127_6366825_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000000004474 209.0
HKD2_k127_6366825_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000008682 155.0
HKD2_k127_6393792_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 303.0
HKD2_k127_6393792_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 289.0
HKD2_k127_6393792_10 Peptidase family M28 - - - 0.0000000000000009702 90.0
HKD2_k127_6393792_11 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000004037 55.0
HKD2_k127_6393792_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 298.0
HKD2_k127_6393792_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002164 278.0
HKD2_k127_6393792_4 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
HKD2_k127_6393792_5 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000000000000000000000001764 195.0
HKD2_k127_6393792_6 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000009615 153.0
HKD2_k127_6393792_7 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000000000000000000000003996 139.0
HKD2_k127_6393792_8 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000004176 92.0
HKD2_k127_6393792_9 - - - - 0.000000000000000007603 96.0
HKD2_k127_6401444_0 Immune inhibitor A peptidase M6 - - - 3.307e-201 645.0
HKD2_k127_6401444_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 537.0
HKD2_k127_6401444_2 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 512.0
HKD2_k127_6401444_3 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 436.0
HKD2_k127_6401444_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 373.0
HKD2_k127_6401444_5 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000003109 254.0
HKD2_k127_6401444_6 PFAM Glycosyl transferase family 2 K07011,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
HKD2_k127_6401444_7 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000001096 157.0
HKD2_k127_645169_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 486.0
HKD2_k127_645169_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 449.0
HKD2_k127_645169_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000006015 163.0
HKD2_k127_645169_3 Belongs to the UPF0109 family K06960 - - 0.000000000000000007603 85.0
HKD2_k127_6484537_0 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 388.0
HKD2_k127_6484537_1 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 374.0
HKD2_k127_6484537_2 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001483 243.0
HKD2_k127_6484537_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000009917 231.0
HKD2_k127_6484537_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000003437 216.0
HKD2_k127_651071_0 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 358.0
HKD2_k127_651071_1 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 317.0
HKD2_k127_651071_10 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000002352 104.0
HKD2_k127_651071_11 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000272 64.0
HKD2_k127_651071_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 298.0
HKD2_k127_651071_3 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005051 271.0
HKD2_k127_651071_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007803 240.0
HKD2_k127_651071_5 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000001934 207.0
HKD2_k127_651071_6 Glycosyltransferase, group 1 family - - - 0.00000000000000000000000000000000000000000000000000009276 201.0
HKD2_k127_651071_7 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000002733 157.0
HKD2_k127_651071_8 Methyltransferase domain - - - 0.00000000000000000000000004793 114.0
HKD2_k127_651071_9 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000005353 121.0
HKD2_k127_6513616_0 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 414.0
HKD2_k127_6513616_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 383.0
HKD2_k127_6513616_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007531 264.0
HKD2_k127_6539038_0 COG NOG15865 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 337.0
HKD2_k127_6539038_1 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001169 214.0
HKD2_k127_6539038_2 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000002369 81.0
HKD2_k127_6540972_0 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 0.0 1034.0
HKD2_k127_6540972_1 PFAM natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 571.0
HKD2_k127_6540972_10 ATPases associated with a variety of cellular activities - - - 0.00000000000000001986 83.0
HKD2_k127_6540972_11 - - - - 0.0000000104 62.0
HKD2_k127_6540972_2 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 381.0
HKD2_k127_6540972_3 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 330.0
HKD2_k127_6540972_4 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 303.0
HKD2_k127_6540972_5 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000009952 269.0
HKD2_k127_6540972_6 epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000009144 260.0
HKD2_k127_6540972_7 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007092 243.0
HKD2_k127_6540972_8 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000003259 237.0
HKD2_k127_6540972_9 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.0000000000000000000000000000000002567 143.0
HKD2_k127_6551606_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 620.0
HKD2_k127_6551606_1 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 431.0
HKD2_k127_6551606_3 - - - - 0.00000000000000000000000000000000000006823 155.0
HKD2_k127_6551606_4 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000889 87.0
HKD2_k127_6551606_5 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000479 67.0
HKD2_k127_6551606_6 PFAM Glycosyl transferase family 2 - - - 0.000000236 52.0
HKD2_k127_6552597_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 443.0
HKD2_k127_6552597_1 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 406.0
HKD2_k127_6552597_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000125 50.0
HKD2_k127_6552597_3 Histidine kinase - - - 0.0007178 51.0
HKD2_k127_6552597_4 Lactoylglutathione lyase and related lyases - - - 0.0007477 48.0
HKD2_k127_6552597_5 Domain of unknown function (DUF4440) - - - 0.0007971 51.0
HKD2_k127_6562934_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 6.309e-225 707.0
HKD2_k127_6562934_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 387.0
HKD2_k127_6562934_2 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 337.0
HKD2_k127_6562934_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000006651 193.0
HKD2_k127_6562934_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000004916 151.0
HKD2_k127_6562934_5 spore germination K03605 - - 0.00000000000000000000000001421 116.0
HKD2_k127_6562934_6 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000003969 98.0
HKD2_k127_6562934_7 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000003652 55.0
HKD2_k127_6566078_0 PFAM Fumarate lyase K01744 - 4.3.1.1 9.034e-202 637.0
HKD2_k127_6566078_1 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 560.0
HKD2_k127_6566078_2 Type II secretion system (T2SS), protein F K12511 - - 0.0000000000000000000000000000000000000000000002729 171.0
HKD2_k127_6566078_3 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000004338 163.0
HKD2_k127_6566078_4 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000174 113.0
HKD2_k127_6566078_5 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000006009 95.0
HKD2_k127_6573_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.383e-314 975.0
HKD2_k127_6573_1 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
HKD2_k127_6573_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000003494 185.0
HKD2_k127_6574101_0 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.00000000000000000000000000000000000000000000000000000000000000004253 226.0
HKD2_k127_6574101_1 - - - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
HKD2_k127_6574101_2 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00000000000000000000000002344 115.0
HKD2_k127_6574101_3 - - - - 0.00000000000005313 75.0
HKD2_k127_65893_0 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 421.0
HKD2_k127_65893_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 450.0
HKD2_k127_65893_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 391.0
HKD2_k127_65893_4 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003702 291.0
HKD2_k127_65893_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000002894 204.0
HKD2_k127_65893_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000003132 198.0
HKD2_k127_65893_7 - K01992 - - 0.00000000000000000000000000000000000000000000000000003476 197.0
HKD2_k127_65893_8 Glycerophosphodiester phosphodiesterase - - - 0.00000000000000000000000000000000000000000000001261 190.0
HKD2_k127_65893_9 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000005964 125.0
HKD2_k127_6597380_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.353e-257 812.0
HKD2_k127_6597380_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 610.0
HKD2_k127_6597380_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 302.0
HKD2_k127_6597380_11 lipid binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 291.0
HKD2_k127_6597380_12 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001661 278.0
HKD2_k127_6597380_13 Anion-transporting ATPase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001344 258.0
HKD2_k127_6597380_14 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000002223 238.0
HKD2_k127_6597380_15 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000009557 226.0
HKD2_k127_6597380_16 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000003686 227.0
HKD2_k127_6597380_17 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001281 217.0
HKD2_k127_6597380_18 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000001149 217.0
HKD2_k127_6597380_19 - - - - 0.000000000000000000000000000000000000000000000000000001422 200.0
HKD2_k127_6597380_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 599.0
HKD2_k127_6597380_20 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000405 184.0
HKD2_k127_6597380_21 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000003224 176.0
HKD2_k127_6597380_22 PFAM low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000306 135.0
HKD2_k127_6597380_23 PFAM phospholipase Carboxylesterase K06999 - - 0.000000000000000000000000000001071 129.0
HKD2_k127_6597380_24 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000001216 96.0
HKD2_k127_6597380_3 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 579.0
HKD2_k127_6597380_4 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 512.0
HKD2_k127_6597380_5 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 448.0
HKD2_k127_6597380_6 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 428.0
HKD2_k127_6597380_7 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 397.0
HKD2_k127_6597380_8 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 375.0
HKD2_k127_6597380_9 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 329.0
HKD2_k127_6622656_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 307.0
HKD2_k127_6622656_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003076 259.0
HKD2_k127_6622656_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001322 257.0
HKD2_k127_6622656_3 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000002983 168.0
HKD2_k127_6622656_4 PFAM Methyltransferase type 11 - - - 0.0000000000000000000008417 96.0
HKD2_k127_6622656_5 - - - - 0.00000000005256 76.0
HKD2_k127_6622656_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000041 61.0
HKD2_k127_6622656_7 Heat shock protein DnaJ domain protein - - - 0.000005418 57.0
HKD2_k127_6627432_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 383.0
HKD2_k127_6627432_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 332.0
HKD2_k127_6630296_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1203.0
HKD2_k127_6630296_1 Fibronectin type III-like domain K05349 - 3.2.1.21 2.579e-294 916.0
HKD2_k127_6630296_2 Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source K01483 - 4.3.2.3 0.0000000000000000000000000000000008615 134.0
HKD2_k127_6630296_3 Transposase - - - 0.000000000000000000000001159 106.0
HKD2_k127_6646324_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 520.0
HKD2_k127_6646324_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 494.0
HKD2_k127_6646324_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 432.0
HKD2_k127_6646324_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 297.0
HKD2_k127_6646324_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001811 278.0
HKD2_k127_6646324_5 SMART helix-turn-helix domain protein K15539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001231 271.0
HKD2_k127_6646324_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
HKD2_k127_6646324_7 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000006697 199.0
HKD2_k127_6648791_0 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 480.0
HKD2_k127_6648791_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 429.0
HKD2_k127_6648791_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 357.0
HKD2_k127_6648791_3 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 305.0
HKD2_k127_6648791_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003458 278.0
HKD2_k127_6648791_5 TIGRFAM phosphate ABC transporter, permease protein PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004296 254.0
HKD2_k127_6648791_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000005831 234.0
HKD2_k127_6648791_7 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000004804 184.0
HKD2_k127_6648791_8 - - - - 0.0000000000000000000008584 102.0
HKD2_k127_6668396_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K08070 - 1.3.1.74,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 360.0
HKD2_k127_6668396_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 324.0
HKD2_k127_6668396_2 FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 320.0
HKD2_k127_6668396_3 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000003701 194.0
HKD2_k127_6668396_4 PQQ-like domain K05889,K12132 - 1.1.2.6,2.7.11.1 0.00000003239 54.0
HKD2_k127_6679341_0 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001945 272.0
HKD2_k127_6679341_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001389 265.0
HKD2_k127_6679341_2 - - - - 0.0000000002409 63.0
HKD2_k127_668018_0 Glycosyltransferase 36 associated - - - 0.0 1281.0
HKD2_k127_668018_1 Bacterial pre-peptidase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 543.0
HKD2_k127_668018_2 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 412.0
HKD2_k127_668018_3 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000003637 229.0
HKD2_k127_668018_4 Hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000003256 107.0
HKD2_k127_668018_5 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000008855 65.0
HKD2_k127_6689095_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.463e-211 674.0
HKD2_k127_6689095_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 596.0
HKD2_k127_6696119_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 456.0
HKD2_k127_6696119_1 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 401.0
HKD2_k127_6696119_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 395.0
HKD2_k127_6696119_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
HKD2_k127_6696119_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000212 283.0
HKD2_k127_6696119_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001904 278.0
HKD2_k127_6696119_8 4Fe-4S dicluster domain - - - 0.00000000000000000000002349 100.0
HKD2_k127_6717028_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.543e-226 711.0
HKD2_k127_6717028_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 4.251e-195 620.0
HKD2_k127_6717028_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 608.0
HKD2_k127_6717028_3 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 542.0
HKD2_k127_6717028_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 460.0
HKD2_k127_6717028_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000705 273.0
HKD2_k127_6717028_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000006551 212.0
HKD2_k127_6717028_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000003147 118.0
HKD2_k127_6717028_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000007432 77.0
HKD2_k127_6743617_0 ABC transporter transmembrane region K06147 - - 2.968e-252 794.0
HKD2_k127_6743617_1 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 324.0
HKD2_k127_6743617_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000194 215.0
HKD2_k127_6743617_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000001367 164.0
HKD2_k127_6743617_4 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000204 157.0
HKD2_k127_6743617_5 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000000000000000004859 126.0
HKD2_k127_6750079_0 intracellular signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 535.0
HKD2_k127_6750079_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 433.0
HKD2_k127_6750079_10 Group 1 family - - - 0.000000000000000000000000000000000000000005701 170.0
HKD2_k127_6750079_11 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000001438 144.0
HKD2_k127_6750079_12 - - - - 0.00000000000000000000021 99.0
HKD2_k127_6750079_13 - - - - 0.00000000000000008817 84.0
HKD2_k127_6750079_14 Ig-like domain from next to BRCA1 gene - - - 0.00000000000633 79.0
HKD2_k127_6750079_15 serine-type aminopeptidase activity K14475 - - 0.00000005886 66.0
HKD2_k127_6750079_16 phytoene synthase K21678 - 2.5.1.103 0.0001942 53.0
HKD2_k127_6750079_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 413.0
HKD2_k127_6750079_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 398.0
HKD2_k127_6750079_4 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 351.0
HKD2_k127_6750079_5 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 302.0
HKD2_k127_6750079_6 Oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001054 279.0
HKD2_k127_6750079_7 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001545 243.0
HKD2_k127_6750079_8 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003464 249.0
HKD2_k127_6750079_9 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
HKD2_k127_6780152_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1165.0
HKD2_k127_6780152_1 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 591.0
HKD2_k127_6780152_2 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 336.0
HKD2_k127_6780152_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 300.0
HKD2_k127_6780152_4 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000851 219.0
HKD2_k127_6780152_6 - - - - 0.0000000000000000000000000000000000000000000000000000004454 205.0
HKD2_k127_6782274_0 HNH nucleases - - - 0.000000000000001376 81.0
HKD2_k127_6782274_1 SdrD B-like domain - - - 0.0000001907 63.0
HKD2_k127_6782274_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000003476 55.0
HKD2_k127_6782274_3 - - - - 0.000267 45.0
HKD2_k127_6829676_0 PFAM Arsenical pump membrane protein K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 484.0
HKD2_k127_6829676_1 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 395.0
HKD2_k127_6829676_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 332.0
HKD2_k127_6829676_3 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 283.0
HKD2_k127_6829676_4 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005531 277.0
HKD2_k127_6829676_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000007955 226.0
HKD2_k127_6829676_6 GTPase activity K06949 - 3.1.3.100 0.000000000000000000001289 100.0
HKD2_k127_6829676_7 - - - - 0.0000000005322 67.0
HKD2_k127_6829676_8 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000001992 60.0
HKD2_k127_6829676_9 membrane protein (homolog of Drosophila rhomboid) K19225 - 3.4.21.105 0.0000003182 60.0
HKD2_k127_6855798_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1527.0
HKD2_k127_6855798_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 356.0
HKD2_k127_6861476_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 462.0
HKD2_k127_6861476_1 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 294.0
HKD2_k127_6861476_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000007951 124.0
HKD2_k127_6861476_4 - - - - 0.00007283 48.0
HKD2_k127_6863817_0 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 540.0
HKD2_k127_6879533_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 534.0
HKD2_k127_6879533_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 443.0
HKD2_k127_6879533_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 390.0
HKD2_k127_6879533_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 357.0
HKD2_k127_6879533_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000004958 71.0
HKD2_k127_688533_0 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K15372 - 2.6.1.55 3.16e-217 681.0
HKD2_k127_688533_1 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 403.0
HKD2_k127_688533_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 237.0
HKD2_k127_688533_3 Acetyltransferase (GNAT) domain K03817 - - 0.0000000000000000000000000000000000001002 145.0
HKD2_k127_6937334_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 525.0
HKD2_k127_6937334_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 307.0
HKD2_k127_6937334_3 alcohol dehydrogenase - - - 0.0000000000000000000000000000917 118.0
HKD2_k127_6937334_5 SpoU rRNA Methylase family - - - 0.00000000003635 64.0
HKD2_k127_7006648_0 Serine threonine protein kinase K12132 - 2.7.11.1 7.646e-264 826.0
HKD2_k127_7006648_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 4.799e-218 682.0
HKD2_k127_7006648_10 GyrI-like small molecule binding domain K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000001477 229.0
HKD2_k127_7006648_11 PFAM Forkhead-associated protein - - - 0.0000000000000000000000000000000000000000005124 162.0
HKD2_k127_7006648_12 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000002064 163.0
HKD2_k127_7006648_13 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000001148 154.0
HKD2_k127_7006648_14 - - - - 0.000000000000000000000000236 107.0
HKD2_k127_7006648_15 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K05873,K12960 - 3.5.4.28,3.5.4.31,4.6.1.1 0.0000000000000001869 81.0
HKD2_k127_7006648_16 Domain of unknown function (DUF4870) - - - 0.000000000000129 75.0
HKD2_k127_7006648_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 526.0
HKD2_k127_7006648_3 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 362.0
HKD2_k127_7006648_4 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 350.0
HKD2_k127_7006648_5 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 314.0
HKD2_k127_7006648_6 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 298.0
HKD2_k127_7006648_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004501 263.0
HKD2_k127_7006648_8 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000005193 259.0
HKD2_k127_7006648_9 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005687 238.0
HKD2_k127_7007188_0 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 411.0
HKD2_k127_7007188_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 416.0
HKD2_k127_7007188_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000002263 209.0
HKD2_k127_7007188_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000007509 192.0
HKD2_k127_7007188_4 acetyltransferase - - - 0.000000000000000002188 96.0
HKD2_k127_7007188_5 - - - - 0.00000000000000002414 93.0
HKD2_k127_7007188_6 Protein of unknown function (DUF2917) - - - 0.0000005268 55.0
HKD2_k127_7080446_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1340.0
HKD2_k127_7080446_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K12955 - 3.6.3.6 0.0 1086.0
HKD2_k127_7080446_10 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001214 255.0
HKD2_k127_7080446_11 Bacterial regulatory proteins, lacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000001388 232.0
HKD2_k127_7080446_12 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000008321 220.0
HKD2_k127_7080446_13 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000000003037 201.0
HKD2_k127_7080446_14 alpha/beta hydrolase fold - GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000001854 199.0
HKD2_k127_7080446_15 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.0000000000000000000000000000000000000000000000000002033 192.0
HKD2_k127_7080446_16 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000004749 194.0
HKD2_k127_7080446_17 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000004991 189.0
HKD2_k127_7080446_18 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000001786 188.0
HKD2_k127_7080446_19 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000003974 180.0
HKD2_k127_7080446_2 COG0038 Chloride channel protein EriC K03281 - - 9.045e-195 627.0
HKD2_k127_7080446_20 - - - - 0.000000000000000000000000000000000000000000008879 166.0
HKD2_k127_7080446_21 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000518 156.0
HKD2_k127_7080446_22 Universal stress protein - - - 0.000000000000000000000000000000000000001099 151.0
HKD2_k127_7080446_23 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000005284 147.0
HKD2_k127_7080446_24 - - - - 0.000000000000000000000000000000000004516 143.0
HKD2_k127_7080446_25 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000004752 130.0
HKD2_k127_7080446_26 - - - - 0.0000004394 53.0
HKD2_k127_7080446_27 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000002566 51.0
HKD2_k127_7080446_28 domain, Protein K15125,K19231 - - 0.000006954 59.0
HKD2_k127_7080446_29 cobalamin binding - - - 0.00003723 46.0
HKD2_k127_7080446_3 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 567.0
HKD2_k127_7080446_30 - - - - 0.0002746 48.0
HKD2_k127_7080446_31 CAAX protease self-immunity - - - 0.0005446 45.0
HKD2_k127_7080446_4 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 544.0
HKD2_k127_7080446_5 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 514.0
HKD2_k127_7080446_6 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 478.0
HKD2_k127_7080446_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 358.0
HKD2_k127_7080446_8 Flavin-binding monooxygenase-like K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 330.0
HKD2_k127_7080446_9 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 335.0
HKD2_k127_7087627_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 3.769e-282 889.0
HKD2_k127_7087627_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 336.0
HKD2_k127_7087627_2 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 301.0
HKD2_k127_7087627_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000009683 228.0
HKD2_k127_7087627_4 WD-40 repeat - - - 0.00000000000000000000000000000000000000000000002543 196.0
HKD2_k127_7087627_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000001738 148.0
HKD2_k127_7087627_6 - - - - 0.0000000000000000000000000000000000002964 143.0
HKD2_k127_7087627_7 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000000000000004303 135.0
HKD2_k127_7087627_8 - - - - 0.00000000000000000000000001315 111.0
HKD2_k127_7087627_9 AAA ATPase domain - - - 0.0000000001068 71.0
HKD2_k127_7088845_0 Terminase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 449.0
HKD2_k127_7088845_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000149 240.0
HKD2_k127_7088845_10 Carboxymuconolactone decarboxylase family - - - 0.00000000000000007291 82.0
HKD2_k127_7088845_11 - - - - 0.000000001953 63.0
HKD2_k127_7088845_12 - - - - 0.00004861 51.0
HKD2_k127_7088845_2 Phage portal protein, lambda family - - - 0.00000000000000000000000000000000000000000000000000000000000004854 231.0
HKD2_k127_7088845_3 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000007751 183.0
HKD2_k127_7088845_4 Aminoglycoside 3-N-acetyltransferase - - - 0.0000000000000000000000000000000002276 142.0
HKD2_k127_7088845_5 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000008018 115.0
HKD2_k127_7088845_6 - - - - 0.00000000000000000000000003776 119.0
HKD2_k127_7088845_7 Glycosyl hydrolases family 25 K07273 - - 0.0000000000000000000001264 108.0
HKD2_k127_7088845_8 Golgi phosphoprotein 3 (GPP34) - - - 0.000000000000000000009408 100.0
HKD2_k127_7088845_9 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000001139 87.0
HKD2_k127_7227234_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 4.042e-244 766.0
HKD2_k127_7227234_1 Amidohydrolase family - - - 3.431e-221 693.0
HKD2_k127_7227234_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 411.0
HKD2_k127_7227234_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 367.0
HKD2_k127_7227234_4 UTRA K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001869 260.0
HKD2_k127_7243457_0 PFAM Cytochrome C assembly protein K02198 - - 3.655e-289 902.0
HKD2_k127_7243457_1 - K07138 - - 3.878e-200 628.0
HKD2_k127_7243457_10 ATPases associated with a variety of cellular activities K02028,K10041 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 321.0
HKD2_k127_7243457_11 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 306.0
HKD2_k127_7243457_12 PFAM Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 304.0
HKD2_k127_7243457_13 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 304.0
HKD2_k127_7243457_14 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 304.0
HKD2_k127_7243457_15 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 295.0
HKD2_k127_7243457_16 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003595 258.0
HKD2_k127_7243457_17 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003935 247.0
HKD2_k127_7243457_18 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000003969 212.0
HKD2_k127_7243457_19 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000002065 215.0
HKD2_k127_7243457_2 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 617.0
HKD2_k127_7243457_20 CYTH domain - - - 0.00000000000000000000000000000000000000000000000000002237 192.0
HKD2_k127_7243457_21 - - - - 0.00000000000000000000000000000000000000000002843 173.0
HKD2_k127_7243457_22 NUDIX domain - - - 0.0000000000000000000000000000000000000000003099 162.0
HKD2_k127_7243457_23 Ribbon-helix-helix domain - - - 0.0000000000000000000000000000000000000000237 161.0
HKD2_k127_7243457_24 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000007662 160.0
HKD2_k127_7243457_25 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000001226 151.0
HKD2_k127_7243457_26 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000006542 147.0
HKD2_k127_7243457_27 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000009402 145.0
HKD2_k127_7243457_28 zinc-ribbon domain - - - 0.00000000000000000002849 97.0
HKD2_k127_7243457_29 - - - - 0.000000001216 68.0
HKD2_k127_7243457_3 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 599.0
HKD2_k127_7243457_30 PFAM Formylglycine-generating sulfatase enzyme K18912,K20333 - 1.14.99.50 0.000001357 52.0
HKD2_k127_7243457_32 Sulfatase-modifying factor enzyme 1 - - - 0.00001675 50.0
HKD2_k127_7243457_33 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0003059 46.0
HKD2_k127_7243457_4 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 431.0
HKD2_k127_7243457_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 401.0
HKD2_k127_7243457_6 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 376.0
HKD2_k127_7243457_7 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 327.0
HKD2_k127_7243457_8 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 325.0
HKD2_k127_7243457_9 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 321.0
HKD2_k127_7329165_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 484.0
HKD2_k127_7329165_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 371.0
HKD2_k127_7329165_10 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.0000000000000000000000000000000000001732 152.0
HKD2_k127_7329165_11 - - - - 0.0000000000000000000000000001534 124.0
HKD2_k127_7329165_13 Domain of unknown function (DUF4203) - - - 0.0000000000000000000000249 106.0
HKD2_k127_7329165_14 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000002621 89.0
HKD2_k127_7329165_15 - - - - 0.000000004731 65.0
HKD2_k127_7329165_16 DNA excision K02806 - - 0.00000009365 57.0
HKD2_k127_7329165_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006796 283.0
HKD2_k127_7329165_3 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000027 234.0
HKD2_k127_7329165_5 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000003493 221.0
HKD2_k127_7329165_6 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000000000001446 198.0
HKD2_k127_7329165_7 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000004083 205.0
HKD2_k127_7329165_8 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.0000000000000000000000000000000000000000000000000006192 192.0
HKD2_k127_7329165_9 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000002708 168.0
HKD2_k127_7381803_0 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 297.0
HKD2_k127_7381803_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000005378 210.0
HKD2_k127_7381803_2 - - - - 0.0000000000000000000000000000000000000000000000000000004542 202.0
HKD2_k127_7381803_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000006098 193.0
HKD2_k127_7381803_4 AAA domain - - - 0.000000000000000000000000000000000000000000000001217 178.0
HKD2_k127_7381803_5 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000001609 157.0
HKD2_k127_7381803_6 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000006495 151.0
HKD2_k127_7381803_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000007425 138.0
HKD2_k127_7381803_8 Serine Threonine protein kinase - - - 0.00000000000000000000000000182 130.0
HKD2_k127_7381803_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0002295 48.0
HKD2_k127_7430789_0 PFAM UbiA prenyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 351.0
HKD2_k127_7430789_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 347.0
HKD2_k127_7430789_2 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 312.0
HKD2_k127_7430789_3 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.000000000000001168 80.0
HKD2_k127_7480520_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.545e-283 878.0
HKD2_k127_7480520_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 361.0
HKD2_k127_7480520_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 354.0
HKD2_k127_7480520_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 332.0
HKD2_k127_7480520_4 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
HKD2_k127_7480520_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
HKD2_k127_7480520_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000001577 166.0
HKD2_k127_7480520_8 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00006381 46.0
HKD2_k127_748083_0 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 456.0
HKD2_k127_748083_1 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000001847 179.0
HKD2_k127_748083_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000002384 160.0
HKD2_k127_7645781_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 524.0
HKD2_k127_7645781_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 345.0
HKD2_k127_7645781_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 324.0
HKD2_k127_7645781_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000006314 224.0
HKD2_k127_7645781_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000004253 72.0
HKD2_k127_7671617_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 338.0
HKD2_k127_7671617_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 299.0
HKD2_k127_7671617_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000001565 232.0
HKD2_k127_7708536_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 414.0
HKD2_k127_7708536_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 401.0
HKD2_k127_7708536_2 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 389.0
HKD2_k127_7708536_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 348.0
HKD2_k127_7708536_4 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 345.0
HKD2_k127_7708536_5 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000006207 280.0
HKD2_k127_7708536_6 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000001247 215.0
HKD2_k127_7708536_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000006302 183.0
HKD2_k127_7708536_8 Transcriptional regulator, GntR family - - - 0.0000000000000000007441 96.0
HKD2_k127_7708536_9 Transcriptional regulator - - - 0.000000000002087 76.0
HKD2_k127_7711260_0 PFAM sodium calcium exchanger membrane region K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 390.0
HKD2_k127_7711260_1 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 341.0
HKD2_k127_7711260_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004925 257.0
HKD2_k127_7711260_3 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000916 150.0
HKD2_k127_7711260_4 diacylglycerol kinase, catalytic region - - - 0.0000000000000000000000000000004277 134.0
HKD2_k127_7711260_5 ribosomal protein L28 K02902 - - 0.00000000000000002285 82.0
HKD2_k127_7711260_6 antibiotic catabolic process K13277 - - 0.00001093 54.0
HKD2_k127_7713532_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 4.566e-208 666.0
HKD2_k127_7713532_1 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 313.0
HKD2_k127_7713532_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000001143 197.0
HKD2_k127_7713532_3 Nickel-containing superoxide dismutase K00518 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.15.1.1 0.0000000000000000000000000000000000000000000000000002532 189.0
HKD2_k127_7713532_4 membrane - - - 0.00000000000000000000000000000000000000004884 163.0
HKD2_k127_7713532_5 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000000009554 127.0
HKD2_k127_7713532_6 alcohol dehydrogenase - - - 0.00000000000000003675 93.0
HKD2_k127_7713532_7 Peptidase S24 - - - 0.0000002636 57.0
HKD2_k127_7715231_0 acyl-CoA dehydrogenase - - - 1.67e-266 830.0
HKD2_k127_7715231_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.79e-239 744.0
HKD2_k127_7715231_10 PFAM phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000008093 134.0
HKD2_k127_7715231_11 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000001463 100.0
HKD2_k127_7715231_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000001821 112.0
HKD2_k127_7715231_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 550.0
HKD2_k127_7715231_3 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 363.0
HKD2_k127_7715231_4 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 294.0
HKD2_k127_7715231_5 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 298.0
HKD2_k127_7715231_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003002 287.0
HKD2_k127_7715231_7 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000007733 202.0
HKD2_k127_7715231_8 exodeoxyribonuclease I activity - - - 0.0000000000000000000000000000000000000000000000000000001572 200.0
HKD2_k127_7715231_9 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000007346 165.0
HKD2_k127_7717916_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 514.0
HKD2_k127_7717916_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 479.0
HKD2_k127_7717916_10 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000507 190.0
HKD2_k127_7717916_11 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000006758 182.0
HKD2_k127_7717916_12 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.000000000000000000000000000000000000000000000006489 174.0
HKD2_k127_7717916_13 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000000000000000000251 173.0
HKD2_k127_7717916_15 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.0000000000000000001652 94.0
HKD2_k127_7717916_2 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 424.0
HKD2_k127_7717916_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 368.0
HKD2_k127_7717916_4 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 292.0
HKD2_k127_7717916_5 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
HKD2_k127_7717916_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003054 268.0
HKD2_k127_7717916_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000001319 255.0
HKD2_k127_7717916_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000004478 243.0
HKD2_k127_7738351_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.201e-275 858.0
HKD2_k127_7738351_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 426.0
HKD2_k127_7738351_10 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000009596 160.0
HKD2_k127_7738351_11 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000000000001965 160.0
HKD2_k127_7738351_12 Mut7-C ubiquitin - - - 0.00000000000000003234 83.0
HKD2_k127_7738351_13 EamA-like transporter family - - - 0.00000000002754 69.0
HKD2_k127_7738351_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 402.0
HKD2_k127_7738351_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 385.0
HKD2_k127_7738351_4 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 301.0
HKD2_k127_7738351_5 transferase activity, transferring glycosyl groups K21011,K21012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 296.0
HKD2_k127_7738351_6 Bacterial sugar transferase K19428 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
HKD2_k127_7738351_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001795 272.0
HKD2_k127_7738351_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000009678 218.0
HKD2_k127_7738351_9 Mo-molybdopterin cofactor metabolic process K03636 - - 0.0000000000000000000000000000000000000000003263 162.0
HKD2_k127_77457_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 377.0
HKD2_k127_77457_1 Histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000003974 204.0
HKD2_k127_77457_2 Phosphopantetheine attachment site - - - 0.00000000000000000000000000002454 119.0
HKD2_k127_77457_3 PFAM GHMP kinase K07031 - 2.7.1.168 0.00000000000000000000008098 98.0
HKD2_k127_77457_4 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000001304 60.0
HKD2_k127_7749059_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.035e-214 676.0
HKD2_k127_7749059_1 Aminotransferase class-III - - - 5.227e-201 634.0
HKD2_k127_7749059_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 490.0
HKD2_k127_7749059_11 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 456.0
HKD2_k127_7749059_12 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 327.0
HKD2_k127_7749059_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006867 248.0
HKD2_k127_7749059_14 Transcription regulator K03718 - - 0.00000000000000000000000000000000000004944 149.0
HKD2_k127_7749059_15 - - - - 0.000000000000000000000000002341 116.0
HKD2_k127_7749059_16 Aldo/keto reductase family - - - 0.0000000000000000000007701 96.0
HKD2_k127_7749059_17 gas vesicle protein - - - 0.0000000000000000009908 90.0
HKD2_k127_7749059_2 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 598.0
HKD2_k127_7749059_3 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821,K05830,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 568.0
HKD2_k127_7749059_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 541.0
HKD2_k127_7749059_5 Aminotransferase class-III K15372 - 2.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 522.0
HKD2_k127_7749059_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 519.0
HKD2_k127_7749059_7 Psort location Cytoplasmic, score 8.87 K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 505.0
HKD2_k127_7749059_8 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 497.0
HKD2_k127_7749059_9 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 484.0
HKD2_k127_7766320_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 8.138e-276 858.0
HKD2_k127_7766320_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 2.74e-236 750.0
HKD2_k127_7766320_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000002727 76.0
HKD2_k127_7766320_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.854e-224 704.0
HKD2_k127_7766320_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 526.0
HKD2_k127_7766320_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 435.0
HKD2_k127_7766320_5 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 420.0
HKD2_k127_7766320_6 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 362.0
HKD2_k127_7766320_7 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 289.0
HKD2_k127_7766320_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000005797 211.0
HKD2_k127_7766320_9 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000004039 166.0
HKD2_k127_7777776_0 DEAD DEAH box helicase domain protein K06877 - - 5.411e-297 935.0
HKD2_k127_7777776_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 8.275e-220 690.0
HKD2_k127_7777776_10 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000003569 185.0
HKD2_k127_7777776_11 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000000000000003797 175.0
HKD2_k127_7777776_12 - - - - 0.000000000000000000000000000000008072 136.0
HKD2_k127_7777776_13 - - - - 0.000000000000000000000279 102.0
HKD2_k127_7777776_14 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000000000000001277 97.0
HKD2_k127_7777776_2 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 541.0
HKD2_k127_7777776_3 DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 511.0
HKD2_k127_7777776_4 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 470.0
HKD2_k127_7777776_5 PFAM aminotransferase class V K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 429.0
HKD2_k127_7777776_6 NAD-dependent epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 313.0
HKD2_k127_7777776_7 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000956 245.0
HKD2_k127_7777776_8 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008528 237.0
HKD2_k127_7777776_9 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000002848 238.0
HKD2_k127_7803360_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 5.214e-247 776.0
HKD2_k127_7803360_1 transporter K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 424.0
HKD2_k127_7803360_2 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 408.0
HKD2_k127_7803360_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 368.0
HKD2_k127_7803360_4 drug transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
HKD2_k127_7803360_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 259.0
HKD2_k127_7803360_6 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000008534 216.0
HKD2_k127_7803360_7 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000000000001452 202.0
HKD2_k127_7820503_0 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000003145 206.0
HKD2_k127_7820503_1 - - - - 0.0000000000000000000000000000000000000000000000000000274 201.0
HKD2_k127_7820503_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000001825 176.0
HKD2_k127_7820503_3 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000001831 83.0
HKD2_k127_7820503_4 Tfp pilus assembly protein FimV - - - 0.000000559 61.0
HKD2_k127_7828860_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1056.0
HKD2_k127_7828860_1 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 2.005e-280 887.0
HKD2_k127_7828860_10 Protease prsW family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007805 280.0
HKD2_k127_7828860_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000001185 242.0
HKD2_k127_7828860_12 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000002001 235.0
HKD2_k127_7828860_13 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000005081 226.0
HKD2_k127_7828860_14 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000003226 194.0
HKD2_k127_7828860_15 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000001893 179.0
HKD2_k127_7828860_16 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000008253 175.0
HKD2_k127_7828860_17 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000001354 170.0
HKD2_k127_7828860_18 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000001405 132.0
HKD2_k127_7828860_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001849 125.0
HKD2_k127_7828860_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 5.378e-273 848.0
HKD2_k127_7828860_21 MazG-like family - - - 0.000000000000000000000000000006359 121.0
HKD2_k127_7828860_22 Peptidase family M48 - - - 0.00000000000000000000008614 108.0
HKD2_k127_7828860_23 Tetratricopeptide TPR_2 repeat protein - - - 0.000000001023 67.0
HKD2_k127_7828860_3 Elongator protein 3, MiaB family, Radical SAM - - - 2.011e-261 820.0
HKD2_k127_7828860_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.564e-247 769.0
HKD2_k127_7828860_5 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 476.0
HKD2_k127_7828860_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 454.0
HKD2_k127_7828860_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 417.0
HKD2_k127_7828860_8 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 372.0
HKD2_k127_7828860_9 Adenosine/AMP deaminase K01488,K18286 GO:0000034,GO:0003674,GO:0003824,GO:0006139,GO:0006144,GO:0006145,GO:0006146,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0046083,GO:0046100,GO:0046101,GO:0046112,GO:0046113,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 291.0
HKD2_k127_7829619_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 409.0
HKD2_k127_7829619_1 PFAM TrkA-N domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 351.0
HKD2_k127_7829619_2 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 284.0
HKD2_k127_7829619_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000002381 223.0
HKD2_k127_7829619_4 Lipid kinase - - - 0.0000000000000000000000000000000000000000000001248 173.0
HKD2_k127_7829619_5 methyltransferase - - - 0.0000000000000000000000000000005042 133.0
HKD2_k127_7829619_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000006971 122.0
HKD2_k127_78309_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 598.0
HKD2_k127_78309_1 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 490.0
HKD2_k127_78309_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 392.0
HKD2_k127_78309_3 sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000996 248.0
HKD2_k127_78309_4 Nudix hydrolase - - - 0.000000000000000000000000000000000000000000000007403 177.0
HKD2_k127_78309_5 Trypsin K04771 - 3.4.21.107 0.000000000000000000000001276 113.0
HKD2_k127_78309_6 AntiSigma factor - - - 0.00000511 58.0
HKD2_k127_7836520_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 348.0
HKD2_k127_7836520_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 334.0
HKD2_k127_7836520_2 Putative membrane peptidase family (DUF2324) - - - 0.0000000000000000000000000000000000000000000000000001009 197.0
HKD2_k127_7836520_3 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000006476 175.0
HKD2_k127_7836520_4 Belongs to the peptidase S8 family - - - 0.0000004409 57.0
HKD2_k127_7853954_0 ATP-dependent transcriptional regulator K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 481.0
HKD2_k127_7853954_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 330.0
HKD2_k127_7859285_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1735.0
HKD2_k127_7859285_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 2.492e-231 724.0
HKD2_k127_7859285_10 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001413 236.0
HKD2_k127_7859285_11 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000003644 243.0
HKD2_k127_7859285_12 - - - - 0.000000000000000000000000000000000000000000000000000000000001975 217.0
HKD2_k127_7859285_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000006175 209.0
HKD2_k127_7859285_14 - - - - 0.000000000000000000000000000000000000000000003387 178.0
HKD2_k127_7859285_15 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000007154 132.0
HKD2_k127_7859285_16 - - - - 0.000000000000000000000000000000005134 137.0
HKD2_k127_7859285_17 - - - - 0.0000000000000000000000009291 112.0
HKD2_k127_7859285_18 Ribosomal protein S21 K02970 - - 0.00000000000000000002215 93.0
HKD2_k127_7859285_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 476.0
HKD2_k127_7859285_21 Peptidoglycan-binding lysin domain - - - 0.000009172 57.0
HKD2_k127_7859285_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 443.0
HKD2_k127_7859285_4 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 427.0
HKD2_k127_7859285_5 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 310.0
HKD2_k127_7859285_6 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 302.0
HKD2_k127_7859285_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 293.0
HKD2_k127_7859285_8 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001215 259.0
HKD2_k127_7859285_9 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000122 265.0
HKD2_k127_787909_0 Belongs to the glycosyl hydrolase 13 family K01187 - 3.2.1.20 1.251e-213 680.0
HKD2_k127_787909_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000002021 211.0
HKD2_k127_787909_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.000000000000000000000005981 108.0
HKD2_k127_787909_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000000121 98.0
HKD2_k127_787909_4 - - - - 0.0000007311 57.0
HKD2_k127_7902080_0 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 423.0
HKD2_k127_7902080_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 372.0
HKD2_k127_7902080_2 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 341.0
HKD2_k127_7902080_3 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 331.0
HKD2_k127_7902080_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 303.0
HKD2_k127_7902080_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000002566 125.0
HKD2_k127_7902080_6 Transglutaminase-like superfamily - - - 0.00000000000000000001626 103.0
HKD2_k127_7925384_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001088 271.0
HKD2_k127_7925384_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001488 257.0
HKD2_k127_7925384_2 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000114 259.0
HKD2_k127_7925384_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000001481 198.0
HKD2_k127_7925384_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000003019 198.0
HKD2_k127_7925384_5 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000000000000000000000000000000000004587 188.0
HKD2_k127_7928732_0 xylulokinase activity K00854 - 2.7.1.17 4.279e-201 636.0
HKD2_k127_7928732_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 437.0
HKD2_k127_7928732_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 433.0
HKD2_k127_7928732_3 import. Responsible for energy coupling to the transport system K10441,K10542 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 421.0
HKD2_k127_7928732_4 KDPG and KHG aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004359 272.0
HKD2_k127_7928732_5 Glucose-6-phosphate isomerase (GPI) K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001357 246.0
HKD2_k127_7928732_6 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000002996 218.0
HKD2_k127_7928732_7 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000001195 169.0
HKD2_k127_7928732_8 ABC-type sugar transport system periplasmic component K10439,K10543 - - 0.000000000000000000000000000000003519 141.0
HKD2_k127_7932695_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.807e-277 872.0
HKD2_k127_7932695_1 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 3.089e-205 646.0
HKD2_k127_7932695_10 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 367.0
HKD2_k127_7932695_11 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 356.0
HKD2_k127_7932695_12 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 349.0
HKD2_k127_7932695_13 Heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 347.0
HKD2_k127_7932695_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 310.0
HKD2_k127_7932695_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 304.0
HKD2_k127_7932695_16 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 294.0
HKD2_k127_7932695_17 polysaccharide biosynthetic process K16694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 301.0
HKD2_k127_7932695_18 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 283.0
HKD2_k127_7932695_19 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
HKD2_k127_7932695_2 PFAM fumarate lyase K01679 - 4.2.1.2 1.968e-195 620.0
HKD2_k127_7932695_20 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000000000000000001523 211.0
HKD2_k127_7932695_21 - - - - 0.00000000000000000000000000000000000000000000000000000000806 216.0
HKD2_k127_7932695_22 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000005777 166.0
HKD2_k127_7932695_23 SnoaL-like domain - - - 0.000000000000000000008116 97.0
HKD2_k127_7932695_24 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000001257 82.0
HKD2_k127_7932695_25 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000003671 71.0
HKD2_k127_7932695_26 DNA internalization competence protein ComEC Rec2-like protein K02238 - - 0.0000000007536 70.0
HKD2_k127_7932695_27 Glycosyltransferase family 87 - - - 0.000003303 59.0
HKD2_k127_7932695_3 CoA-transferase family III K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 482.0
HKD2_k127_7932695_4 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 434.0
HKD2_k127_7932695_5 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 440.0
HKD2_k127_7932695_6 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 413.0
HKD2_k127_7932695_7 translation release factor activity K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 393.0
HKD2_k127_7932695_8 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 387.0
HKD2_k127_7932695_9 L-asparaginase II K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 366.0
HKD2_k127_7932945_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.314e-232 723.0
HKD2_k127_7932945_1 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 430.0
HKD2_k127_7932945_2 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 301.0
HKD2_k127_7932945_3 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K22479 - - 0.000000000000000000000000000001144 124.0
HKD2_k127_7968142_0 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 602.0
HKD2_k127_7968142_1 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 400.0
HKD2_k127_7968142_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000004109 200.0
HKD2_k127_7968142_3 Divergent PAP2 family K09775 - - 0.0000000000000000000000000000000000000000000004321 170.0
HKD2_k127_7968142_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000004917 68.0
HKD2_k127_7971154_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.304e-235 741.0
HKD2_k127_7971154_1 domain, Protein K01219,K17624 - 3.2.1.81,3.2.1.97 6.58e-214 684.0
HKD2_k127_7971154_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000598 229.0
HKD2_k127_7971154_11 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000006298 200.0
HKD2_k127_7971154_12 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000001951 170.0
HKD2_k127_7971154_13 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000002007 162.0
HKD2_k127_7971154_14 Rieske [2Fe-2S] domain K03886 - - 0.000000000000000000000000000001705 126.0
HKD2_k127_7971154_15 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.00000000000000000000000004095 125.0
HKD2_k127_7971154_16 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000001629 74.0
HKD2_k127_7971154_17 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000002058 72.0
HKD2_k127_7971154_18 Cytochrome c - - - 0.00000001372 68.0
HKD2_k127_7971154_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000002005 61.0
HKD2_k127_7971154_2 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 585.0
HKD2_k127_7971154_3 tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 574.0
HKD2_k127_7971154_4 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 374.0
HKD2_k127_7971154_5 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 377.0
HKD2_k127_7971154_6 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 298.0
HKD2_k127_7971154_7 Cytochrome b/b6/petB K00412,K03888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000137 239.0
HKD2_k127_7971154_8 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000004509 244.0
HKD2_k127_7971154_9 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000004717 223.0
HKD2_k127_7983406_0 GMC oxidoreductase - - - 4.644e-220 694.0
HKD2_k127_7983406_1 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 365.0
HKD2_k127_7983406_2 - - - - 0.000000000000000000000000000000000001374 147.0
HKD2_k127_7983406_3 endonuclease containing a URI domain K07461 - - 0.00000000000001017 76.0
HKD2_k127_7983406_4 Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.0000000001692 66.0
HKD2_k127_7983406_5 Evidence 4 Homologs of previously reported genes of K07461 - - 0.0001496 44.0
HKD2_k127_7998111_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000001539 212.0
HKD2_k127_7998111_1 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000007899 169.0
HKD2_k127_8003372_0 ABC transporter transmembrane region K06147 - - 5.802e-257 803.0
HKD2_k127_8003372_1 ABC transporter transmembrane region K06147 - - 5.865e-248 779.0
HKD2_k127_8033145_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1199.0
HKD2_k127_8033145_1 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 3.829e-271 847.0
HKD2_k127_8033145_10 Domain of unknown function DUF11 - - - 0.00001463 57.0
HKD2_k127_8033145_11 serine-type aminopeptidase activity - - - 0.00001736 53.0
HKD2_k127_8033145_2 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 516.0
HKD2_k127_8033145_3 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 289.0
HKD2_k127_8033145_4 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000191 280.0
HKD2_k127_8033145_5 4Fe-4S dicluster domain K00196 - - 0.0000000000000000000000000000000000000000000000000000000000003585 218.0
HKD2_k127_8033145_6 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000002096 115.0
HKD2_k127_8033145_7 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000002103 110.0
HKD2_k127_8060859_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 601.0
HKD2_k127_8060859_1 FAD binding domain K00278,K03388 - 1.4.3.16,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 602.0
HKD2_k127_8060859_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 393.0
HKD2_k127_8060859_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000365 256.0
HKD2_k127_8060859_4 Isochorismatase family K09020 - 3.5.1.110 0.00000000000000001154 91.0
HKD2_k127_8065790_0 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 302.0
HKD2_k127_8065790_1 L COG3436 Transposase and inactivated derivatives K07484 - - 0.000000000000000000106 94.0
HKD2_k127_8065790_2 Transposase IS66 family K07484 - - 0.0000000000003057 72.0
HKD2_k127_8065790_3 Transposase IS66 family - - - 0.0007284 46.0
HKD2_k127_8065790_4 PFAM Transposase IS66 family K07484 - - 0.0008381 44.0
HKD2_k127_8081335_0 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 600.0
HKD2_k127_8081335_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000006721 207.0
HKD2_k127_8081335_3 - - - - 0.0000000000001346 75.0
HKD2_k127_8081335_4 LuxR family transcriptional regulator - - - 0.0003098 51.0
HKD2_k127_8083853_0 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 411.0
HKD2_k127_8083853_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 361.0
HKD2_k127_8083853_10 Protein of unknown function (DUF4230) - - - 0.00000000000000000000000000000000006308 142.0
HKD2_k127_8083853_11 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000000008448 123.0
HKD2_k127_8083853_12 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000004446 122.0
HKD2_k127_8083853_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000002494 120.0
HKD2_k127_8083853_14 phosphorelay signal transduction system - - - 0.000000000000000000000007699 106.0
HKD2_k127_8083853_15 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000004305 101.0
HKD2_k127_8083853_2 Enoyl-(Acyl carrier protein) reductase K00059,K00068 - 1.1.1.100,1.1.1.140 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 306.0
HKD2_k127_8083853_3 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 305.0
HKD2_k127_8083853_4 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 297.0
HKD2_k127_8083853_5 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 296.0
HKD2_k127_8083853_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006263 267.0
HKD2_k127_8083853_7 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001548 242.0
HKD2_k127_8083853_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000815 180.0
HKD2_k127_8083853_9 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000001033 170.0
HKD2_k127_8131598_0 Alpha-Mannosidase K01191,K15524 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 3.2.1.170,3.2.1.24 1.196e-267 856.0
HKD2_k127_8131598_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 2.354e-258 819.0
HKD2_k127_8131598_10 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003931 268.0
HKD2_k127_8131598_11 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002219 267.0
HKD2_k127_8131598_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000002601 222.0
HKD2_k127_8131598_13 Nacht domain K13730 - - 0.00000000000000000000000000000000000000000000000005016 193.0
HKD2_k127_8131598_14 cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000001526 136.0
HKD2_k127_8131598_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000005811 90.0
HKD2_k127_8131598_16 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000004123 78.0
HKD2_k127_8131598_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.584e-209 666.0
HKD2_k127_8131598_3 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 516.0
HKD2_k127_8131598_4 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 512.0
HKD2_k127_8131598_5 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 373.0
HKD2_k127_8131598_6 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 361.0
HKD2_k127_8131598_7 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 347.0
HKD2_k127_8131598_8 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 330.0
HKD2_k127_8131598_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000174 273.0
HKD2_k127_8134361_0 PFAM IstB domain protein ATP-binding protein K02315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 515.0
HKD2_k127_8134361_1 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 384.0
HKD2_k127_8134361_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 323.0
HKD2_k127_8134361_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004109 264.0
HKD2_k127_8134361_4 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000002754 235.0
HKD2_k127_8134361_5 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000001646 212.0
HKD2_k127_8134361_6 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000001182 146.0
HKD2_k127_8134361_7 TIGRFAM primosome, DnaD subunit - - - 0.0000000000000000000000000000000000003242 149.0
HKD2_k127_8134361_8 - - - - 0.00000000000000000000000000004433 130.0
HKD2_k127_8227609_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 295.0
HKD2_k127_8227609_1 PFAM Radical SAM domain protein - - - 0.0000000000000003083 81.0
HKD2_k127_8246679_0 N-terminal 7TM region of histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 563.0
HKD2_k127_8246679_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 533.0
HKD2_k127_8246679_10 acetyltransferase K06889,K19273 - - 0.000000000000000000000000000000000000002697 153.0
HKD2_k127_8246679_11 TIGRFAM competence protein ComEA helix-hairpin-helix repeat protein K02237 - - 0.0000000000000000000000000000000000002378 147.0
HKD2_k127_8246679_12 - - - - 0.0000000000000000000000000000000000163 144.0
HKD2_k127_8246679_13 Sigma-70 region 2 K03088 - - 0.0000000000000000000000001932 113.0
HKD2_k127_8246679_14 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.000000000000000000001678 96.0
HKD2_k127_8246679_15 transcriptional - - - 0.000000000000000001043 94.0
HKD2_k127_8246679_16 - - - - 0.000002113 57.0
HKD2_k127_8246679_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 454.0
HKD2_k127_8246679_3 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 408.0
HKD2_k127_8246679_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 381.0
HKD2_k127_8246679_5 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 342.0
HKD2_k127_8246679_6 PFAM RNA binding S1 domain protein K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 310.0
HKD2_k127_8246679_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 302.0
HKD2_k127_8246679_8 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000007833 191.0
HKD2_k127_8246679_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000005548 167.0
HKD2_k127_8312338_0 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 488.0
HKD2_k127_8312338_1 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 331.0
HKD2_k127_8312338_10 - - - - 0.000007015 52.0
HKD2_k127_8312338_3 - - - - 0.00000000000000000000000000000000000009285 155.0
HKD2_k127_8312338_4 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.00000000000000000000000000000004172 136.0
HKD2_k127_8312338_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000004768 136.0
HKD2_k127_8312338_6 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000009303 98.0
HKD2_k127_8312338_7 - - - - 0.00000000000000005106 91.0
HKD2_k127_8312338_8 - - - - 0.0000000000000000786 83.0
HKD2_k127_8312338_9 sh3 domain protein K01448,K04771 - 3.4.21.107,3.5.1.28 0.000002566 60.0
HKD2_k127_8319900_0 COGs COG3533 conserved K09955 - - 2.758e-234 742.0
HKD2_k127_8319900_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000002736 209.0
HKD2_k127_832924_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 386.0
HKD2_k127_832924_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003308 274.0
HKD2_k127_832924_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007914 280.0
HKD2_k127_832924_3 phosphoglycerate mutase - - - 0.00000000000008382 76.0
HKD2_k127_832924_4 SNARE-like domain protein - - - 0.0001409 52.0
HKD2_k127_8330374_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 421.0
HKD2_k127_8330374_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 341.0
HKD2_k127_8330374_10 - - - - 0.000000000000000000000000004723 118.0
HKD2_k127_8330374_11 Domain of unknown function (DUF4342) - - - 0.0000000000000000000007445 97.0
HKD2_k127_8330374_12 GIY-YIG catalytic domain - - - 0.000000000000000000003628 95.0
HKD2_k127_8330374_13 methyltransferase activity - - - 0.0000000000000000001358 92.0
HKD2_k127_8330374_14 - - - - 0.000000000000001806 85.0
HKD2_k127_8330374_15 TIGRFAM C_GCAxxG_C_C family protein - - - 0.00000000000001639 74.0
HKD2_k127_8330374_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000235 79.0
HKD2_k127_8330374_17 Belongs to the peptidase M50B family K06402 - - 0.000000000198 71.0
HKD2_k127_8330374_18 - - - - 0.0000000002266 64.0
HKD2_k127_8330374_2 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000015 278.0
HKD2_k127_8330374_20 Acetyltransferase (GNAT) family - - - 0.0000001562 63.0
HKD2_k127_8330374_3 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000006697 245.0
HKD2_k127_8330374_4 Domain of unknown function (DUF4287) - - - 0.00000000000000000000000000000000000000000000000005526 184.0
HKD2_k127_8330374_5 homoserine kinase type II (protein kinase fold) - - - 0.000000000000000000000000000000000000000000000221 180.0
HKD2_k127_8330374_6 Butirosin biosynthesis protein H, N-terminal - - - 0.000000000000000000000000000000000000001027 160.0
HKD2_k127_8330374_7 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000003386 147.0
HKD2_k127_8330374_8 Hemerythrin HHE cation binding - - - 0.00000000000000000000000000000000000852 144.0
HKD2_k127_8330374_9 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000001118 125.0
HKD2_k127_8352700_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 345.0
HKD2_k127_8352700_1 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000001808 207.0
HKD2_k127_8352700_2 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000001366 192.0
HKD2_k127_8352700_3 cellulase activity K01178,K14645,K18546 - 3.2.1.3 0.00000000000000000000000000004569 128.0
HKD2_k127_8352700_4 ABC-2 family transporter protein - - - 0.0000000000000000000006816 100.0
HKD2_k127_8352700_5 - - - - 0.000000001809 63.0
HKD2_k127_8352700_6 Helix-turn-helix - - - 0.0001727 45.0
HKD2_k127_8385181_0 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 426.0
HKD2_k127_8385181_1 fad dependent oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 374.0
HKD2_k127_8385181_2 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
HKD2_k127_8385181_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000003141 160.0
HKD2_k127_8385181_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000001111 144.0
HKD2_k127_8385181_6 DNA alkylation repair enzyme - - - 0.0000000261 64.0
HKD2_k127_8425233_0 peptidase - - - 1.378e-255 801.0
HKD2_k127_8425233_1 Zn_pept - - - 3.29e-239 751.0
HKD2_k127_8425233_10 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 325.0
HKD2_k127_8425233_11 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 312.0
HKD2_k127_8425233_12 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 300.0
HKD2_k127_8425233_13 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 284.0
HKD2_k127_8425233_14 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003798 287.0
HKD2_k127_8425233_15 Lipid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000252 278.0
HKD2_k127_8425233_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000001899 243.0
HKD2_k127_8425233_17 Ribosomal protein L11 methyltransferase (PrmA) K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000000009543 233.0
HKD2_k127_8425233_18 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000005504 206.0
HKD2_k127_8425233_19 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000008406 198.0
HKD2_k127_8425233_2 protein kinase activity - - - 1.627e-226 737.0
HKD2_k127_8425233_20 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000002023 201.0
HKD2_k127_8425233_21 CHAD - - - 0.000000000000000000000000000000000000000000000000000005912 207.0
HKD2_k127_8425233_22 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000008395 173.0
HKD2_k127_8425233_23 aspartic-type endopeptidase activity K02236,K02506,K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000002102 174.0
HKD2_k127_8425233_24 NUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.0000000000000000000000000000000000000000001431 166.0
HKD2_k127_8425233_25 Methyltransferase type 11 - - - 0.0000000000000000000000000000001705 132.0
HKD2_k127_8425233_26 Redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000001104 126.0
HKD2_k127_8425233_27 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.00000000000000000000000000006884 119.0
HKD2_k127_8425233_29 Pfam Wyosine base formation - - - 0.0004454 49.0
HKD2_k127_8425233_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.743e-206 648.0
HKD2_k127_8425233_4 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 465.0
HKD2_k127_8425233_5 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 461.0
HKD2_k127_8425233_6 extracellular polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 452.0
HKD2_k127_8425233_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 439.0
HKD2_k127_8425233_8 PFAM TrkA-N domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 350.0
HKD2_k127_8425233_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 333.0
HKD2_k127_8517884_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 451.0
HKD2_k127_8517884_1 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000025 200.0
HKD2_k127_8519300_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 535.0
HKD2_k127_8519300_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 394.0
HKD2_k127_8519300_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001042 253.0
HKD2_k127_8519300_3 Transposase IS200 like - - - 0.000000000000000000000000000000003724 134.0
HKD2_k127_8519300_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000001441 117.0
HKD2_k127_8519300_5 Ribosomal L27 protein K02899 - - 0.0000000000000000000000000002538 115.0
HKD2_k127_8519300_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000000001487 113.0
HKD2_k127_8519300_7 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000001229 53.0
HKD2_k127_8639649_0 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 403.0
HKD2_k127_8639649_1 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000002868 164.0
HKD2_k127_8639649_2 Acyltransferase family - - - 0.0000000000000000000000001225 113.0
HKD2_k127_8639649_3 ubiE/COQ5 methyltransferase family - - - 0.00001368 55.0
HKD2_k127_8649978_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.034e-312 978.0
HKD2_k127_8649978_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 423.0
HKD2_k127_8649978_10 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000005538 143.0
HKD2_k127_8649978_11 VIT family - - - 0.00000000000000000000000000002389 127.0
HKD2_k127_8649978_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000001945 94.0
HKD2_k127_8649978_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 351.0
HKD2_k127_8649978_3 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 341.0
HKD2_k127_8649978_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004939 297.0
HKD2_k127_8649978_5 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006119 283.0
HKD2_k127_8649978_6 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009273 253.0
HKD2_k127_8649978_7 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000155 219.0
HKD2_k127_8649978_8 Methyltransferase - - - 0.000000000000000000000000000000000000000000000001205 184.0
HKD2_k127_8649978_9 MarR family - - - 0.0000000000000000000000000000000000006217 148.0
HKD2_k127_8669385_0 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001175 201.0
HKD2_k127_8669385_1 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000004687 157.0
HKD2_k127_8669385_2 bis(5'-adenosyl)-triphosphatase activity K02503 - - 0.00000000000000000000000000000000000004662 148.0
HKD2_k127_8669385_3 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000002601 133.0
HKD2_k127_8669385_4 TIGRFAM C_GCAxxG_C_C family protein - - - 0.00000000000000000000000002812 111.0
HKD2_k127_8669385_5 Psort location Extracellular, score 9.64 - - - 0.0000000000000000000005335 110.0
HKD2_k127_8669385_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000003901 99.0
HKD2_k127_8669385_7 cellulose binding - - - 0.00000000000002502 86.0
HKD2_k127_8669385_8 T5orf172 domain K07461 - - 0.00002868 47.0
HKD2_k127_8711864_0 Heat shock 70 kDa protein K04043 - - 9.183e-298 924.0
HKD2_k127_8711864_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 2.093e-278 873.0
HKD2_k127_8711864_10 TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC K16012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 410.0
HKD2_k127_8711864_11 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 314.0
HKD2_k127_8711864_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 317.0
HKD2_k127_8711864_13 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
HKD2_k127_8711864_14 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000007113 190.0
HKD2_k127_8711864_15 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000001056 181.0
HKD2_k127_8711864_17 NUDIX domain - - - 0.000000000000000000000000001737 130.0
HKD2_k127_8711864_18 ubiE/COQ5 methyltransferase family - - - 0.000000000001075 76.0
HKD2_k127_8711864_19 Permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000002517 75.0
HKD2_k127_8711864_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 607.0
HKD2_k127_8711864_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 531.0
HKD2_k127_8711864_4 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 501.0
HKD2_k127_8711864_5 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 491.0
HKD2_k127_8711864_6 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 471.0
HKD2_k127_8711864_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 452.0
HKD2_k127_8711864_8 Heparinase II/III-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 466.0
HKD2_k127_8711864_9 peptidase M29 aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 433.0
HKD2_k127_8729649_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 322.0
HKD2_k127_8729649_1 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.000000000000000000000000000000000000000000000000000000000000000000000000002832 267.0
HKD2_k127_8729649_2 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.0000000000000000000000000000000002371 145.0
HKD2_k127_8729649_3 Glycosyl transferase family 2 - - - 0.0001454 46.0
HKD2_k127_8779089_0 cobalamin binding - - - 6.232e-265 824.0
HKD2_k127_8779089_1 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 566.0
HKD2_k127_8779089_10 PFAM alpha beta hydrolase fold - - - 0.00000000000003071 78.0
HKD2_k127_8779089_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001185 248.0
HKD2_k127_8779089_3 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000000001162 226.0
HKD2_k127_8779089_4 chain release factor K15034 - - 0.000000000000000000000000000000000000000002729 158.0
HKD2_k127_8779089_5 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000532 171.0
HKD2_k127_8779089_6 Cyclic-di-AMP receptor - - - 0.000000000000000000000000598 108.0
HKD2_k127_8779089_7 Cyclic-di-AMP receptor - - - 0.0000000000000000000009324 97.0
HKD2_k127_8779089_8 conserved protein (DUF2156) K14205 - 2.3.2.3 0.00000000000000000001656 105.0
HKD2_k127_8779089_9 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000008089 83.0
HKD2_k127_878573_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2029.0
HKD2_k127_878573_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1069.0
HKD2_k127_878573_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008834 264.0
HKD2_k127_878573_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000002397 241.0
HKD2_k127_878573_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000008629 229.0
HKD2_k127_878573_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000002235 220.0
HKD2_k127_8819210_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 460.0
HKD2_k127_8819210_1 Formate/nitrite transporter K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 358.0
HKD2_k127_8819210_2 phosphorelay signal transduction system K07670 - - 0.0000000000000000000000000000000000000000000000000000000000003442 218.0
HKD2_k127_8819210_3 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000001008 222.0
HKD2_k127_8824622_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 2.647e-318 999.0
HKD2_k127_8824622_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 1.478e-233 735.0
HKD2_k127_8824622_10 proteolysis K21140 - 3.13.1.6 0.000000000000000000000001371 108.0
HKD2_k127_8824622_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 450.0
HKD2_k127_8824622_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 335.0
HKD2_k127_8824622_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 283.0
HKD2_k127_8824622_5 glycosyl transferase group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000002876 273.0
HKD2_k127_8824622_6 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000005113 226.0
HKD2_k127_8824622_7 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000002847 199.0
HKD2_k127_8824622_9 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000002772 112.0
HKD2_k127_8968550_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 532.0
HKD2_k127_8968550_1 6-phosphogluconolactonase activity K00036,K01057 GO:0000166,GO:0002262,GO:0002376,GO:0002520,GO:0003674,GO:0003824,GO:0004344,GO:0004345,GO:0005488,GO:0005515,GO:0005536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006066,GO:0006081,GO:0006098,GO:0006139,GO:0006518,GO:0006575,GO:0006629,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006749,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009051,GO:0009058,GO:0009117,GO:0009892,GO:0009898,GO:0009987,GO:0010605,GO:0010732,GO:0010734,GO:0016020,GO:0016051,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016788,GO:0017057,GO:0019222,GO:0019321,GO:0019322,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0021700,GO:0030097,GO:0030099,GO:0030154,GO:0030218,GO:0030246,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0033554,GO:0034101,GO:0034599,GO:0034641,GO:0036094,GO:0042221,GO:0042592,GO:0042802,GO:0042803,GO:0043249,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046165,GO:0046364,GO:0046390,GO:0046483,GO:0046496,GO:0046983,GO:0047935,GO:0047936,GO:0048029,GO:0048037,GO:0048468,GO:0048469,GO:0048513,GO:0048519,GO:0048523,GO:0048534,GO:0048731,GO:0048821,GO:0048856,GO:0048869,GO:0048872,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051172,GO:0051186,GO:0051246,GO:0051248,GO:0051716,GO:0052689,GO:0055086,GO:0055114,GO:0060255,GO:0061515,GO:0065007,GO:0065008,GO:0070887,GO:0071695,GO:0071704,GO:0071944,GO:0072524,GO:0080090,GO:0090407,GO:0097159,GO:0098552,GO:0098562,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653 1.1.1.363,1.1.1.49,3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 292.0
HKD2_k127_8968550_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 283.0
HKD2_k127_8968550_3 YbaB/EbfC DNA-binding family K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000001979 114.0
HKD2_k127_8995985_0 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000006872 243.0
HKD2_k127_8995985_1 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000007555 180.0
HKD2_k127_8995985_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000005656 175.0
HKD2_k127_8995985_3 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000000000005787 140.0
HKD2_k127_9003129_0 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000001621 182.0
HKD2_k127_9003129_1 - - - - 0.0000000000000000000000000000000000000003879 162.0
HKD2_k127_9006751_0 Beta-lactamase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 508.0
HKD2_k127_9006751_1 beta-galactosidase activity K01190,K17624 - 3.2.1.23,3.2.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006168 498.0
HKD2_k127_9006751_12 SMART RNA-processing protein HAT helix repeating-containing protein - - - 0.00000000000000000001437 109.0
HKD2_k127_9006751_13 - - - - 0.0000000000000004969 84.0
HKD2_k127_9006751_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 512.0
HKD2_k127_9006751_3 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 456.0
HKD2_k127_9006751_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 393.0
HKD2_k127_9006751_5 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 351.0
HKD2_k127_9006751_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 336.0
HKD2_k127_9006751_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003321 282.0
HKD2_k127_9006751_8 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008145 248.0
HKD2_k127_9006751_9 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002068 240.0
HKD2_k127_9029928_0 PFAM Shikimate quinate 5-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 351.0
HKD2_k127_9029928_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 343.0
HKD2_k127_9029928_2 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 315.0
HKD2_k127_9029928_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 293.0
HKD2_k127_9029928_4 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000003741 171.0
HKD2_k127_9029928_5 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.000000000000000000000000000000000000000003603 160.0
HKD2_k127_9029928_6 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.0000000000000000000000000000000000000001299 156.0
HKD2_k127_9049512_0 PFAM SMC domain protein K03546 - - 9.057e-199 648.0
HKD2_k127_9049512_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 432.0
HKD2_k127_9049512_2 Thg1 C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 380.0
HKD2_k127_9049512_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 339.0
HKD2_k127_9049512_4 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 304.0
HKD2_k127_9049512_5 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000008384 200.0
HKD2_k127_9049512_6 AAA domain - - - 0.0000000000000000000000000000000000000000000000000208 185.0
HKD2_k127_9049512_7 transferase activity, transferring glycosyl groups K14597 - - 0.00000000000004871 78.0
HKD2_k127_9075943_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 2.333e-233 732.0
HKD2_k127_9075943_1 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 422.0
HKD2_k127_9075943_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004856 272.0
HKD2_k127_9075943_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
HKD2_k127_9075943_4 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000004514 207.0
HKD2_k127_9075943_5 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.00000000000000000000000000000000000000000000000001597 189.0
HKD2_k127_9075943_6 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000003016 170.0
HKD2_k127_9075943_7 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000006901 119.0
HKD2_k127_9075943_9 Ethyl tert-butyl ether degradation - - - 0.0006382 49.0
HKD2_k127_9092672_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 3.863e-303 960.0
HKD2_k127_9092672_1 Pfam FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 554.0
HKD2_k127_9092672_10 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 321.0
HKD2_k127_9092672_11 PFAM dihydrodipicolinate synthetase K01714,K21062 - 3.5.4.22,4.3.3.7 0.000000000000000000000000000000000000000000000000000134 197.0
HKD2_k127_9092672_12 sh3 domain protein K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000003538 174.0
HKD2_k127_9092672_13 maltose binding K15770,K15771 - - 0.0000000000000000000000000000001467 142.0
HKD2_k127_9092672_14 PFAM ROK family protein - - - 0.000000000000000000000002114 106.0
HKD2_k127_9092672_15 iron-sulfur cluster insertion protein erpA K15724 - - 0.00000000000000000000001098 105.0
HKD2_k127_9092672_16 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00002869 48.0
HKD2_k127_9092672_17 virion core protein (lumpy skin disease virus) - - - 0.0002211 51.0
HKD2_k127_9092672_2 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 548.0
HKD2_k127_9092672_3 maltose binding K15770,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 516.0
HKD2_k127_9092672_4 PFAM Alpha amylase, catalytic K01176,K01208 GO:0000272,GO:0000287,GO:0001871,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005975,GO:0005976,GO:0005982,GO:0005983,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0016020,GO:0016052,GO:0016160,GO:0016787,GO:0016798,GO:0019867,GO:0030246,GO:0030247,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046872,GO:0071704,GO:1901575,GO:2001070 3.2.1.1,3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 500.0
HKD2_k127_9092672_5 Alpha amylase, catalytic domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 487.0
HKD2_k127_9092672_6 transmembrane transport K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 464.0
HKD2_k127_9092672_7 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 432.0
HKD2_k127_9092672_8 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 375.0
HKD2_k127_9092672_9 PFAM binding-protein-dependent transport systems inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 371.0
HKD2_k127_9095561_0 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000002435 140.0
HKD2_k127_9095561_1 Butirosin biosynthesis protein H, N-terminal - - - 0.0000000000000000000000000004797 120.0
HKD2_k127_9095561_2 homoserine kinase activity - - - 0.00000000000000000000000272 106.0
HKD2_k127_9095561_3 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000001144 102.0
HKD2_k127_9095561_4 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000003077 57.0
HKD2_k127_9109708_0 carbon starvation protein CstA K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 525.0
HKD2_k127_9109708_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 492.0
HKD2_k127_9109708_10 Berberine and berberine like - - - 0.000000000000000000000000000000000000000000001264 169.0
HKD2_k127_9109708_11 - - - - 0.00000000000000000000000000000000000001424 145.0
HKD2_k127_9109708_12 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000001399 127.0
HKD2_k127_9109708_13 beta-lactamase - - - 0.0000000000000000000000001023 111.0
HKD2_k127_9109708_15 - - - - 0.0000000000000000000008901 98.0
HKD2_k127_9109708_16 ABC-2 family transporter protein K01992 - - 0.000000001595 69.0
HKD2_k127_9109708_17 Tetratricopeptide repeat - - - 0.00005887 53.0
HKD2_k127_9109708_18 ABC-2 type transporter K01992 - - 0.0001 54.0
HKD2_k127_9109708_2 transferase activity, transferring acyl groups K15520 - 2.3.1.189 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 324.0
HKD2_k127_9109708_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 308.0
HKD2_k127_9109708_4 PFAM ABC transporter related K01990,K16907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
HKD2_k127_9109708_5 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001634 264.0
HKD2_k127_9109708_6 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000001528 236.0
HKD2_k127_9109708_7 tungstate ion transport K01990,K07705,K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000002977 238.0
HKD2_k127_9109708_8 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000004885 199.0
HKD2_k127_9109708_9 - - - - 0.00000000000000000000000000000000000000000000000343 185.0
HKD2_k127_9140239_0 PA domain - - - 0.0 1147.0
HKD2_k127_9140239_1 elongation factor Tu domain 2 protein K02355 - - 5e-324 1002.0
HKD2_k127_9140239_10 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000004294 228.0
HKD2_k127_9140239_11 methyltransferase activity K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000005774 163.0
HKD2_k127_9140239_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 569.0
HKD2_k127_9140239_3 peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 417.0
HKD2_k127_9140239_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 294.0
HKD2_k127_9140239_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 295.0
HKD2_k127_9140239_6 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004167 282.0
HKD2_k127_9140239_7 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000007122 271.0
HKD2_k127_9140239_8 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003507 260.0
HKD2_k127_9140239_9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K04708 - 1.1.1.102 0.000000000000000000000000000000000000000000000000000000000000000005767 235.0
HKD2_k127_9158576_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.458e-204 644.0
HKD2_k127_9158576_1 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 605.0
HKD2_k127_9158576_10 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 345.0
HKD2_k127_9158576_11 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 318.0
HKD2_k127_9158576_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 344.0
HKD2_k127_9158576_13 glycerophosphodiester transmembrane transport K17246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 284.0
HKD2_k127_9158576_14 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002848 259.0
HKD2_k127_9158576_15 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000003089 177.0
HKD2_k127_9158576_16 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000006482 161.0
HKD2_k127_9158576_17 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000000008729 86.0
HKD2_k127_9158576_18 domain protein - - - 0.00000000000002922 79.0
HKD2_k127_9158576_19 Nucleoside H+ symporter K05820 - - 0.000002665 55.0
HKD2_k127_9158576_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 570.0
HKD2_k127_9158576_20 Two component transcriptional regulator, winged helix family K07667 - - 0.000002842 56.0
HKD2_k127_9158576_21 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000008774 50.0
HKD2_k127_9158576_22 Transmembrane secretion effector - - - 0.0002456 48.0
HKD2_k127_9158576_3 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 458.0
HKD2_k127_9158576_4 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 434.0
HKD2_k127_9158576_5 carbohydrate transport K02027,K17244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 424.0
HKD2_k127_9158576_6 PFAM ROK family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 396.0
HKD2_k127_9158576_7 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 385.0
HKD2_k127_9158576_8 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 362.0
HKD2_k127_9158576_9 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K10118,K10233,K15771,K17245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 349.0
HKD2_k127_9217855_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1128.0
HKD2_k127_9217855_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 1.494e-223 699.0
HKD2_k127_9217855_10 cyclic nucleotide binding K10914 - - 0.000000000000000000000000002866 118.0
HKD2_k127_9217855_11 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000001075 113.0
HKD2_k127_9217855_12 Domain of unknown function DUF87 K06915 - - 0.000000000000000001165 86.0
HKD2_k127_9217855_13 Hydrogenase maturation protease - - - 0.000000000000000005225 90.0
HKD2_k127_9217855_2 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 481.0
HKD2_k127_9217855_3 Helicase conserved C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 461.0
HKD2_k127_9217855_4 4Fe-4S dicluster domain K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 354.0
HKD2_k127_9217855_5 coenzyme F420 hydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 309.0
HKD2_k127_9217855_6 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 293.0
HKD2_k127_9217855_7 NurA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002339 252.0
HKD2_k127_9217855_9 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000003658 159.0
HKD2_k127_9243386_0 PFAM Aminotransferase class I and II K05825 - - 1.824e-196 619.0
HKD2_k127_9243386_1 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000009215 148.0
HKD2_k127_9243386_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.0000000000000000007378 94.0
HKD2_k127_9247424_0 glucan 1,4-alpha-glucosidase activity - - - 1.19e-233 740.0
HKD2_k127_9247424_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 7.023e-220 709.0
HKD2_k127_9247424_10 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 338.0
HKD2_k127_9247424_11 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 336.0
HKD2_k127_9247424_12 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 328.0
HKD2_k127_9247424_13 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 316.0
HKD2_k127_9247424_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 313.0
HKD2_k127_9247424_15 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 310.0
HKD2_k127_9247424_16 amino acid activation for nonribosomal peptide biosynthetic process K14379 - 3.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 313.0
HKD2_k127_9247424_17 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 308.0
HKD2_k127_9247424_18 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 299.0
HKD2_k127_9247424_19 metallophosphoesterase K07096,K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001744 284.0
HKD2_k127_9247424_2 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 621.0
HKD2_k127_9247424_20 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003047 259.0
HKD2_k127_9247424_21 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000987 240.0
HKD2_k127_9247424_22 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000006707 229.0
HKD2_k127_9247424_23 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000001724 215.0
HKD2_k127_9247424_24 - - - - 0.00000000000000000000000000000000000000000000002368 179.0
HKD2_k127_9247424_25 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000002516 173.0
HKD2_k127_9247424_26 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000002311 173.0
HKD2_k127_9247424_27 - - - - 0.0000000000000000000000000000000000000000000008522 181.0
HKD2_k127_9247424_28 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002094 169.0
HKD2_k127_9247424_29 LysM domain - - - 0.000000000000000000000000000000000000000003064 166.0
HKD2_k127_9247424_3 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 537.0
HKD2_k127_9247424_30 - - - - 0.000000000000000000000000000000000000000003172 162.0
HKD2_k127_9247424_31 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000001075 159.0
HKD2_k127_9247424_32 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000006104 146.0
HKD2_k127_9247424_33 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000003381 133.0
HKD2_k127_9247424_34 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000004976 132.0
HKD2_k127_9247424_35 acetyltransferase K00621 - 2.3.1.4 0.00000000000000000000000000000005714 137.0
HKD2_k127_9247424_36 - - - - 0.0000000000000000000000000009764 117.0
HKD2_k127_9247424_37 Haem-degrading - - - 0.000000000000000000000000001961 116.0
HKD2_k127_9247424_38 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000001679 100.0
HKD2_k127_9247424_4 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 541.0
HKD2_k127_9247424_40 Double zinc ribbon - - - 0.0000000000000009697 87.0
HKD2_k127_9247424_41 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000001231 59.0
HKD2_k127_9247424_42 ThiS family K03636 - - 0.000001224 55.0
HKD2_k127_9247424_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 476.0
HKD2_k127_9247424_6 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 448.0
HKD2_k127_9247424_7 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 433.0
HKD2_k127_9247424_8 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 426.0
HKD2_k127_9247424_9 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 374.0
HKD2_k127_9249394_0 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 612.0
HKD2_k127_9249394_1 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 526.0
HKD2_k127_9249394_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 373.0
HKD2_k127_9249394_3 - - - - 0.00000000000000000000000000000000002232 140.0
HKD2_k127_9249394_4 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000001079 77.0
HKD2_k127_9258222_0 adenosylmethionine-8-amino-7-oxononanoate transaminase activity K15372 - 2.6.1.55 1.349e-213 671.0
HKD2_k127_9258222_1 RNA-binding PUA-like domain of methyltransferase RsmF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 401.0
HKD2_k127_9258222_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000001774 235.0
HKD2_k127_9258222_3 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.000000000000000000000000001466 112.0
HKD2_k127_9258668_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1311.0
HKD2_k127_9258668_1 Bacterial extracellular solute-binding protein - - - 4.251e-195 620.0
HKD2_k127_9258668_2 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 488.0
HKD2_k127_9258668_3 COG3209 Rhs family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005978 235.0
HKD2_k127_9258668_4 Phage integrase family - - - 0.000000000000000000000000000000000000000002584 163.0
HKD2_k127_9258668_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000002591 120.0
HKD2_k127_9258668_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000001011 79.0
HKD2_k127_9258668_7 PFAM transposase mutator type - - - 0.000000000000001567 81.0
HKD2_k127_9258668_8 Involved in the tonB-independent uptake of proteins K12132,K20276 - 2.7.11.1 0.000000005001 68.0
HKD2_k127_9269215_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1015.0
HKD2_k127_9269215_1 PFAM ABC transporter related K06158 - - 1.408e-209 671.0
HKD2_k127_9269215_10 ABC transporter K01990 - - 0.00000000000000000000000000000000000008235 150.0
HKD2_k127_9269215_11 - - - - 0.000000000000000000000000000000000005314 139.0
HKD2_k127_9269215_12 PFAM Stage V sporulation protein S K06416 - - 0.000000000000000000000000000002219 122.0
HKD2_k127_9269215_13 - - - - 0.00000000000000000000003646 106.0
HKD2_k127_9269215_15 - - - - 0.00002868 55.0
HKD2_k127_9269215_2 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 471.0
HKD2_k127_9269215_3 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 423.0
HKD2_k127_9269215_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 414.0
HKD2_k127_9269215_5 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 413.0
HKD2_k127_9269215_6 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 332.0
HKD2_k127_9269215_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004922 302.0
HKD2_k127_9269215_8 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000009176 175.0
HKD2_k127_9285263_0 Carboxypeptidase Taq (M32) metallopeptidase K01299 - 3.4.17.19 3.01e-224 704.0
HKD2_k127_9285263_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.522e-196 619.0
HKD2_k127_9285263_10 COG0784 FOG CheY-like receiver - - - 0.00000000000000000000000000000000000000000000003001 174.0
HKD2_k127_9285263_11 Protein of unknown function (DUF1641) - - - 0.000000000000000000000000000000000000000000007449 171.0
HKD2_k127_9285263_12 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000002767 162.0
HKD2_k127_9285263_13 SnoaL-like domain - - - 0.0000000000000000000000000000003211 126.0
HKD2_k127_9285263_14 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000009605 124.0
HKD2_k127_9285263_15 - - - - 0.00000000000000000000000001761 116.0
HKD2_k127_9285263_16 Transposase - - - 0.000000000000000001281 87.0
HKD2_k127_9285263_2 exo-alpha-(2->6)-sialidase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 581.0
HKD2_k127_9285263_3 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 311.0
HKD2_k127_9285263_4 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
HKD2_k127_9285263_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000006378 229.0
HKD2_k127_9285263_6 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000005419 229.0
HKD2_k127_9285263_7 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000003597 206.0
HKD2_k127_9285263_8 PFAM DinB family protein - - - 0.000000000000000000000000000000000000000000000000000000000463 207.0
HKD2_k127_9285263_9 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000003015 210.0
HKD2_k127_9291175_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 1.383e-308 957.0
HKD2_k127_9291175_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 8.885e-286 888.0
HKD2_k127_9291175_2 Radical_SAM C-terminal domain K07739 - 2.3.1.48 2.543e-236 741.0
HKD2_k127_9294015_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.886e-290 903.0
HKD2_k127_9294015_1 Protein of unknown function, DUF255 K06888 - - 7.977e-210 673.0
HKD2_k127_9294015_10 Phosphotransferase enzyme family K18844 - - 0.000000000000000000000000000000000000000006391 160.0
HKD2_k127_9294015_11 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000003916 140.0
HKD2_k127_9294015_12 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000003831 128.0
HKD2_k127_9294015_13 FR47-like protein - - - 0.000000000000000000007383 99.0
HKD2_k127_9294015_14 GNAT acetyltransferase - - - 0.0000000000000000003705 96.0
HKD2_k127_9294015_2 PFAM glycosidase PH1107-related K18785,K20885 - 2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 527.0
HKD2_k127_9294015_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 521.0
HKD2_k127_9294015_4 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 513.0
HKD2_k127_9294015_5 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 360.0
HKD2_k127_9294015_6 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005185 287.0
HKD2_k127_9294015_7 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002173 266.0
HKD2_k127_9294015_8 COGs COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.0000000000000000000000000000000000000000000000000000000001155 211.0
HKD2_k127_9294015_9 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000003952 166.0
HKD2_k127_9320282_0 PFAM major facilitator superfamily MFS_1 K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 415.0
HKD2_k127_9320282_1 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 407.0
HKD2_k127_9320282_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 379.0
HKD2_k127_9320282_3 PFAM tRNA rRNA methyltransferase (SpoU) K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002904 249.0
HKD2_k127_9320282_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000001829 218.0
HKD2_k127_9320282_5 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000001583 177.0
HKD2_k127_9320282_6 bacterial-type flagellum-dependent swarming motility - - - 0.000000000000000000000000000000000001469 155.0
HKD2_k127_9320282_7 - K03686 - - 0.0000000000002026 73.0
HKD2_k127_9320282_8 - - - - 0.0000000003022 63.0
HKD2_k127_9379740_0 abc transporter atp-binding protein K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004284 261.0
HKD2_k127_9379740_1 Cystathionine beta-synthase K01697 - 4.2.1.22 0.000000000000000000000000000000000000000000000005924 185.0
HKD2_k127_9379740_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000008034 173.0
HKD2_k127_9379740_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000434 150.0
HKD2_k127_9379740_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000448 129.0
HKD2_k127_9379740_5 FCD - - - 0.0000000000000000000000002936 113.0
HKD2_k127_9379740_6 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000008711 70.0
HKD2_k127_9384996_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 501.0
HKD2_k127_9384996_1 Coenzyme F420 hydrogenase dehydrogenase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 312.0
HKD2_k127_9384996_10 sirohydrochlorin cobaltochelatase activity - - - 0.000001674 49.0
HKD2_k127_9384996_2 EamA-like transporter family K03298 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 292.0
HKD2_k127_9384996_3 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001478 293.0
HKD2_k127_9384996_4 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001118 265.0
HKD2_k127_9384996_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007958 261.0
HKD2_k127_9384996_6 Thioredoxin - - - 0.0000000000000000000000000000000226 130.0
HKD2_k127_9384996_7 TfoX N-terminal domain - - - 0.0000000000000000000000001514 111.0
HKD2_k127_9384996_8 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000003112 105.0
HKD2_k127_9384996_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000006282 75.0
HKD2_k127_9392220_0 Transcriptional activator domain - - - 3.416e-225 735.0
HKD2_k127_9392220_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 417.0
HKD2_k127_9392220_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 350.0
HKD2_k127_9392220_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000002409 238.0
HKD2_k127_9392220_4 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000000009142 110.0
HKD2_k127_9392220_5 Polymorphic membrane protein, Chlamydia - - - 0.00000000000000000000000331 109.0
HKD2_k127_9392220_6 - - - - 0.000000000000000002048 86.0
HKD2_k127_9456449_0 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 407.0
HKD2_k127_9456449_1 PFAM Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 377.0
HKD2_k127_9456449_2 Winged helix DNA-binding domain K09927 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 301.0
HKD2_k127_9456449_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008397 290.0
HKD2_k127_9456449_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000002014 223.0
HKD2_k127_9456449_5 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000003342 219.0
HKD2_k127_9456449_6 Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000811 216.0
HKD2_k127_9456449_7 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000001631 134.0
HKD2_k127_9456449_8 YCII-related domain - - - 0.000000000001504 68.0
HKD2_k127_9502033_0 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 553.0
HKD2_k127_9502033_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 450.0
HKD2_k127_9502033_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 420.0
HKD2_k127_9503307_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000294 111.0
HKD2_k127_9503307_1 PFAM lipopolysaccharide biosynthesis protein K08253 - 2.7.10.2 0.0000000000000002993 83.0
HKD2_k127_9507351_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 520.0
HKD2_k127_9507351_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 434.0
HKD2_k127_9507351_2 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 348.0
HKD2_k127_9507351_3 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 314.0
HKD2_k127_9507351_4 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000126 233.0
HKD2_k127_9507351_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000009073 164.0
HKD2_k127_9507351_6 Hydrolase, NUDIX family K03574,K17816 - 3.6.1.55,3.6.1.56 0.0000000000000000000000000000000000000006725 153.0
HKD2_k127_9507351_7 DUF218 domain - - - 0.00000000000002333 81.0
HKD2_k127_9507351_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0006369 52.0
HKD2_k127_9538487_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 614.0
HKD2_k127_9538487_1 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 275.0
HKD2_k127_9538487_2 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0000000000000000000000000000000002656 137.0
HKD2_k127_9554064_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003029 299.0
HKD2_k127_9554064_1 Acetylornithine deacetylase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006319 283.0
HKD2_k127_9554064_2 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006996 252.0
HKD2_k127_9554064_3 zinc-ribbon domain - - - 0.00000000000164 74.0
HKD2_k127_9568466_0 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000001415 121.0
HKD2_k127_9568466_1 amine dehydrogenase activity - - - 0.0000000000004983 83.0
HKD2_k127_9568466_2 HlyD membrane-fusion protein of T1SS K02005 - - 0.000001709 61.0
HKD2_k127_9568466_3 HlyD family secretion protein K02005 - - 0.00000688 59.0
HKD2_k127_9617569_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 304.0
HKD2_k127_9617569_1 PFAM Haloacid dehalogenase domain protein hydrolase K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001445 283.0
HKD2_k127_9617569_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000001192 83.0
HKD2_k127_9710161_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000007328 195.0
HKD2_k127_9710161_1 RNA-binding protein - - - 0.0000000000000000000003614 98.0
HKD2_k127_9710161_2 CarD-like/TRCF domain K07736 - - 0.000000008931 63.0
HKD2_k127_9715715_0 -O-antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 563.0
HKD2_k127_9715715_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 479.0
HKD2_k127_9715715_10 Nacht domain K13730 - - 0.0000000000000000000000000000000000000000000000000000000000005481 229.0
HKD2_k127_9715715_11 adenosylhomocysteine nucleosidase activity K01239,K01243,K03716 - 3.2.2.1,3.2.2.9,4.1.99.14 0.00000000000000000000000000000000000000000000000000001425 198.0
HKD2_k127_9715715_12 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000000000000000000000000000001043 171.0
HKD2_k127_9715715_13 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000009248 160.0
HKD2_k127_9715715_14 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000000000000000000000001914 112.0
HKD2_k127_9715715_15 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000008247 77.0
HKD2_k127_9715715_16 Putative regulatory protein - - - 0.000000000009593 68.0
HKD2_k127_9715715_2 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 415.0
HKD2_k127_9715715_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 367.0
HKD2_k127_9715715_4 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 340.0
HKD2_k127_9715715_5 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 319.0
HKD2_k127_9715715_6 dolichyl monophosphate biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004665 276.0
HKD2_k127_9715715_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000001592 257.0
HKD2_k127_9715715_8 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000006676 226.0
HKD2_k127_9715715_9 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000003471 216.0
HKD2_k127_984384_0 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000000000000000000000002107 227.0
HKD2_k127_984384_1 Peptidase family M20/M25/M40 - - - 0.00000000000000000000000646 104.0
HKD2_k127_984384_2 nitrogen compound transport K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0000000000004685 75.0
HKD2_k127_9861863_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000633 84.0
HKD2_k127_9866824_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 332.0
HKD2_k127_9866824_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007588 239.0
HKD2_k127_9866824_2 - K06039,K07092 - - 0.00000000000000000000000000000000000000000000007008 171.0
HKD2_k127_9866824_3 sulfur carrier activity K00549,K04085 - 2.1.1.14 0.00000003215 63.0
HKD2_k127_9916456_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 3.808e-234 733.0
HKD2_k127_9916456_1 PFAM amidohydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 554.0
HKD2_k127_9916456_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000004628 168.0
HKD2_k127_9916456_12 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000000105 149.0
HKD2_k127_9916456_13 XRE family K21498 - - 0.000000000000000000000000000000000000002798 148.0
HKD2_k127_9916456_2 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 510.0
HKD2_k127_9916456_3 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 463.0
HKD2_k127_9916456_4 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 449.0
HKD2_k127_9916456_5 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 434.0
HKD2_k127_9916456_6 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 361.0
HKD2_k127_9916456_7 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000001846 215.0
HKD2_k127_9916456_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000155 190.0
HKD2_k127_9916456_9 PFAM LmbE family protein - - - 0.000000000000000000000000000000000000000000000000001923 191.0