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Overview

ID MAG01778
Name HKD2_bin.19
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfuromonadia
Order Geobacterales
Family Geobacteraceae
Genus Geomonas
Species
Assembly information
Completeness (%) 99.97
Contamination (%) 4.27
GC content (%) 60.0
N50 (bp) 20,458
Genome size (bp) 5,001,585

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4180

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10210417_0 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 476.0
HKD2_k127_10210417_1 TIGRFAM Phage - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 456.0
HKD2_k127_10210417_10 - - - - 0.000000000000000000000000000000000000000000000000006239 189.0
HKD2_k127_10210417_12 glycosyltransferase - - - 0.000000000000000000000000000000000000000000009323 174.0
HKD2_k127_10210417_13 - - - - 0.000000000000000000000000000000000000000004053 164.0
HKD2_k127_10210417_14 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000004047 158.0
HKD2_k127_10210417_15 chromosome segregation - - - 0.00000000000000000000000000000000000000007624 158.0
HKD2_k127_10210417_16 Phage prohead protease, HK97 family - - - 0.000000000000000000000000000000000000005245 166.0
HKD2_k127_10210417_17 - - - - 0.00000000000000000000000000000000000005843 160.0
HKD2_k127_10210417_18 Rubrerythrin - - - 0.0000000000000000000000000000000000006603 151.0
HKD2_k127_10210417_19 Pkd domain containing protein - - - 0.00000000000000000000000000000000003459 145.0
HKD2_k127_10210417_2 ftsk spoiiie K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 447.0
HKD2_k127_10210417_20 - - - - 0.00000000000000000000000000000000007132 143.0
HKD2_k127_10210417_21 Phage Mu protein F like protein - - - 0.0000000000000000000000000000000001716 146.0
HKD2_k127_10210417_22 - - - - 0.0000000000000000000000000000000005927 144.0
HKD2_k127_10210417_23 - - - - 0.000000000000000000000000000000001815 139.0
HKD2_k127_10210417_24 - - - - 0.00000000000000000000000000000006431 132.0
HKD2_k127_10210417_25 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000009818 131.0
HKD2_k127_10210417_26 O-methyltransferase activity - - - 0.00000000000000000000000000003904 123.0
HKD2_k127_10210417_27 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000002025 118.0
HKD2_k127_10210417_28 AAA domain K14680 - 6.5.1.3 0.0000000000000000000000002831 110.0
HKD2_k127_10210417_29 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000314 118.0
HKD2_k127_10210417_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003665 272.0
HKD2_k127_10210417_30 - - - - 0.0000000000000000000000432 109.0
HKD2_k127_10210417_31 - - - - 0.0000000000000000000005504 106.0
HKD2_k127_10210417_32 Cache_2 - - - 0.00000000000000000000426 100.0
HKD2_k127_10210417_33 - - - - 0.000000000000000001505 93.0
HKD2_k127_10210417_35 Polysaccharide deacetylase - - - 0.00000000000000004629 97.0
HKD2_k127_10210417_36 - - - - 0.0000000000000001917 91.0
HKD2_k127_10210417_37 - - - - 0.0000000000000008632 90.0
HKD2_k127_10210417_38 - - - - 0.000000000000004781 82.0
HKD2_k127_10210417_39 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0000000000001519 77.0
HKD2_k127_10210417_4 Phage tail tape measure protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007835 284.0
HKD2_k127_10210417_40 VRR-NUC domain - - - 0.000000000001459 74.0
HKD2_k127_10210417_42 - - - - 0.00000000005572 69.0
HKD2_k127_10210417_43 - - - - 0.00000000007909 69.0
HKD2_k127_10210417_44 - - - - 0.0000000007716 68.0
HKD2_k127_10210417_45 Mu-like prophage protein gpG - - - 0.000001115 56.0
HKD2_k127_10210417_46 serine threonine protein kinase - - - 0.000003879 54.0
HKD2_k127_10210417_48 - - - - 0.00003408 53.0
HKD2_k127_10210417_49 - - - - 0.00005906 52.0
HKD2_k127_10210417_5 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001411 256.0
HKD2_k127_10210417_50 Transcriptional regulator - - - 0.0002645 47.0
HKD2_k127_10210417_51 - - - - 0.000642 54.0
HKD2_k127_10210417_52 Protein of unknown function (DUF1360) - - - 0.0006682 47.0
HKD2_k127_10210417_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002423 252.0
HKD2_k127_10210417_7 cyclopropane-fatty-acyl-phospholipid synthase K00574,K09846,K21192 - 2.1.1.210,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000864 214.0
HKD2_k127_10210417_8 Participates in initiation and elongation during chromosome replication - - - 0.0000000000000000000000000000000000000000000000000000000004653 227.0
HKD2_k127_10210417_9 hydrolase, family 25 - - - 0.000000000000000000000000000000000000000000000000000007981 198.0
HKD2_k127_10211172_0 - - - - 0.0000008438 60.0
HKD2_k127_1050457_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1120.0
HKD2_k127_1050457_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 7.132e-268 827.0
HKD2_k127_1050457_10 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000001152 96.0
HKD2_k127_1050457_12 - - - - 0.0000000000001174 83.0
HKD2_k127_1050457_13 Protein of unknown function (DUF2845) - - - 0.00000000001873 69.0
HKD2_k127_1050457_14 Chitinase class I K03791 - - 0.00000004043 65.0
HKD2_k127_1050457_15 - - - - 0.000001603 57.0
HKD2_k127_1050457_2 Nucleoside-specific channel-forming protein, Tsx - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 368.0
HKD2_k127_1050457_3 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 314.0
HKD2_k127_1050457_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003566 260.0
HKD2_k127_1050457_5 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000001638 182.0
HKD2_k127_1050457_7 Chitinase class I K03791 - - 0.0000000000000000000000000000000000001533 154.0
HKD2_k127_1050457_9 - - - - 0.00000000000000000000000001846 110.0
HKD2_k127_1096803_0 COG0433 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 434.0
HKD2_k127_113883_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.00000000000000000000000000000009084 132.0
HKD2_k127_113883_1 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000001347 120.0
HKD2_k127_113883_2 - - - - 0.0000000000002633 73.0
HKD2_k127_114942_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3270.0
HKD2_k127_114942_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1380.0
HKD2_k127_114942_11 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000002 198.0
HKD2_k127_114942_12 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000001338 185.0
HKD2_k127_114942_13 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000000001785 133.0
HKD2_k127_114942_14 - - - - 0.000000005111 62.0
HKD2_k127_114942_16 Histidine kinase K02482 - 2.7.13.3 0.00002222 56.0
HKD2_k127_114942_2 PFAM Aldehyde dehydrogenase K00131 - 1.2.1.9 1.283e-301 930.0
HKD2_k127_114942_3 Pfam:KaiC K08482 - - 4.778e-212 668.0
HKD2_k127_114942_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.028e-195 636.0
HKD2_k127_114942_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 380.0
HKD2_k127_114942_6 LysM domain K08307,K12204,K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003 268.0
HKD2_k127_114942_7 HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007096 262.0
HKD2_k127_114942_8 ribonuclease BN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005054 264.0
HKD2_k127_114942_9 PFAM Transcriptional regulator, histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000004139 238.0
HKD2_k127_1169531_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 492.0
HKD2_k127_1169531_1 PFAM Transposase DDE domain - - - 0.000006093 48.0
HKD2_k127_1223122_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 503.0
HKD2_k127_1223122_1 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000000000000000000001709 236.0
HKD2_k127_1223122_2 COGs COG3316 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000009642 138.0
HKD2_k127_1223122_3 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000008753 119.0
HKD2_k127_1223122_4 Transposase - - - 0.0000001793 57.0
HKD2_k127_1223122_5 COGs COG3316 Transposase and inactivated derivatives - - - 0.000004111 50.0
HKD2_k127_1223122_6 - K07498 - - 0.00055 46.0
HKD2_k127_1288373_0 Histidine kinase K07646 - 2.7.13.3 0.0 1386.0
HKD2_k127_1288373_1 amino acid - - - 6.617e-294 910.0
HKD2_k127_1288373_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.927e-275 849.0
HKD2_k127_1288373_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 296.0
HKD2_k127_1289242_0 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 486.0
HKD2_k127_1289242_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 448.0
HKD2_k127_1289242_2 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000001303 242.0
HKD2_k127_1290426_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 366.0
HKD2_k127_1290426_1 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000000000000000000000000000000000000000003361 168.0
HKD2_k127_1301007_0 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 484.0
HKD2_k127_1301007_1 PFAM ROSMUCR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000244 223.0
HKD2_k127_1301007_2 ParB-like nuclease domain K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.000000000000000000000001654 106.0
HKD2_k127_1315063_0 - - - - 0.0 1085.0
HKD2_k127_1315063_1 Pyruvate carboxyltransferase K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 5.456e-219 683.0
HKD2_k127_1315063_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 452.0
HKD2_k127_1315063_3 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 433.0
HKD2_k127_1315063_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00006798 56.0
HKD2_k127_1315976_0 response regulator K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 564.0
HKD2_k127_1326726_0 AcrB/AcrD/AcrF family - - - 0.0 1060.0
HKD2_k127_1338465_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 subunit K00164 - 1.2.4.2 0.0 1446.0
HKD2_k127_1338465_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1337.0
HKD2_k127_1338465_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 334.0
HKD2_k127_1338465_11 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 304.0
HKD2_k127_1338465_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 292.0
HKD2_k127_1338465_13 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 287.0
HKD2_k127_1338465_15 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
HKD2_k127_1338465_16 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000000000000008556 181.0
HKD2_k127_1338465_17 HNH nucleases - - - 0.00000000000000000000000000000000000000001079 153.0
HKD2_k127_1338465_18 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000002157 64.0
HKD2_k127_1338465_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1099.0
HKD2_k127_1338465_3 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.0 1023.0
HKD2_k127_1338465_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 2.739e-304 949.0
HKD2_k127_1338465_5 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 6.193e-241 752.0
HKD2_k127_1338465_6 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 542.0
HKD2_k127_1338465_7 Two component signalling adaptor domain K03415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 511.0
HKD2_k127_1338465_8 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 400.0
HKD2_k127_1338465_9 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 379.0
HKD2_k127_13387_0 - - - - 0.00000000000000000000000000000000005301 137.0
HKD2_k127_13387_1 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000001453 97.0
HKD2_k127_13387_2 - - - - 0.00000000000000000002389 92.0
HKD2_k127_13387_4 - - - - 0.0000000000000007538 78.0
HKD2_k127_13387_5 - - - - 0.000000000000003727 79.0
HKD2_k127_13387_6 - - - - 0.00000000003577 64.0
HKD2_k127_13387_7 - - - - 0.00002848 49.0
HKD2_k127_1362861_0 Belongs to the DEAD box helicase family K03732,K05592 - 3.6.4.13 9.061e-239 746.0
HKD2_k127_1362861_1 WYL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 541.0
HKD2_k127_1363297_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 1.131e-208 653.0
HKD2_k127_1363297_1 PFAM alpha beta hydrolase fold K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 407.0
HKD2_k127_1363297_2 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 343.0
HKD2_k127_1374105_0 DNA ligase K01971 - 6.5.1.1 0.0 1242.0
HKD2_k127_1374105_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 441.0
HKD2_k127_1374105_2 Biogenesis protein K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
HKD2_k127_1374105_3 Domain of unknown function (DUF2383) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001558 256.0
HKD2_k127_1374105_5 - - - - 0.0000000000000000000101 92.0
HKD2_k127_1374105_6 Helix-turn-helix domain - - - 0.0000000000000000000153 93.0
HKD2_k127_1374105_7 UPF0391 membrane protein - - - 0.000000000000000006096 84.0
HKD2_k127_137930_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 508.0
HKD2_k127_137930_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 392.0
HKD2_k127_137930_2 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000002346 119.0
HKD2_k127_137930_3 - - - - 0.00000000000000001817 90.0
HKD2_k127_1380506_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1702.0
HKD2_k127_1380506_1 elongation factor Tu domain 2 protein K06207 - - 0.0 1129.0
HKD2_k127_1380506_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 5.75e-229 717.0
HKD2_k127_1380506_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.961e-222 692.0
HKD2_k127_1380506_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 6.337e-222 691.0
HKD2_k127_1380506_13 impB/mucB/samB family K02346 - 2.7.7.7 2.137e-218 683.0
HKD2_k127_1380506_14 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.611e-216 673.0
HKD2_k127_1380506_15 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 1.294e-210 665.0
HKD2_k127_1380506_16 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 6.375e-210 659.0
HKD2_k127_1380506_17 Peptidoglycan polymerase that is essential for cell division K03588 - - 7.456e-208 650.0
HKD2_k127_1380506_18 Belongs to the methyltransferase superfamily K07444,K12297 - 2.1.1.173,2.1.1.264 7.299e-205 644.0
HKD2_k127_1380506_19 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 608.0
HKD2_k127_1380506_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0 1047.0
HKD2_k127_1380506_20 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 569.0
HKD2_k127_1380506_21 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 577.0
HKD2_k127_1380506_22 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 512.0
HKD2_k127_1380506_23 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 499.0
HKD2_k127_1380506_24 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 477.0
HKD2_k127_1380506_25 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 470.0
HKD2_k127_1380506_26 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 438.0
HKD2_k127_1380506_27 Essential cell division protein K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 427.0
HKD2_k127_1380506_28 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 379.0
HKD2_k127_1380506_29 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 372.0
HKD2_k127_1380506_3 Acetyl-CoA hydrolase/transferase N-terminal domain K01067,K18118 - 2.8.3.18,3.1.2.1 0.0 1014.0
HKD2_k127_1380506_30 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 349.0
HKD2_k127_1380506_31 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 296.0
HKD2_k127_1380506_32 Histidine kinase K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 297.0
HKD2_k127_1380506_33 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002821 250.0
HKD2_k127_1380506_34 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000005804 222.0
HKD2_k127_1380506_35 - - - - 0.0000000000000000000000000000000000000000000000000000000001175 209.0
HKD2_k127_1380506_36 - - - - 0.000000000000000000000000000000000000000000000000000000002168 200.0
HKD2_k127_1380506_37 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000001194 204.0
HKD2_k127_1380506_38 Cell division protein FtsL - - - 0.0000000000000000000000000000000000000000000000000335 180.0
HKD2_k127_1380506_39 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.00000000000000000000003289 102.0
HKD2_k127_1380506_4 Chemotaxis sensory transducer K03406 - - 3.597e-320 992.0
HKD2_k127_1380506_40 Sel1-like repeats. K07126 - - 0.00000000003202 73.0
HKD2_k127_1380506_41 - - - - 0.000000003693 64.0
HKD2_k127_1380506_5 Histidine kinase - - - 2.474e-281 886.0
HKD2_k127_1380506_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.911e-269 833.0
HKD2_k127_1380506_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 4.757e-256 797.0
HKD2_k127_1380506_8 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.998e-255 788.0
HKD2_k127_1380506_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 3.746e-249 775.0
HKD2_k127_1381081_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1382.0
HKD2_k127_1381081_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 499.0
HKD2_k127_1381081_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386,K20011 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 375.0
HKD2_k127_1381081_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000009199 214.0
HKD2_k127_1381081_4 - - - - 0.000000000000000000000000000000000000000000001992 168.0
HKD2_k127_1381081_5 4Fe-4S binding domain - - - 0.00000000000000000002147 90.0
HKD2_k127_1382237_0 Transposase IS4 family - - - 1.765e-212 670.0
HKD2_k127_1382237_1 - - - - 0.000000101 59.0
HKD2_k127_1382628_0 Cys/Met metabolism PLP-dependent enzyme - - - 6.986e-210 657.0
HKD2_k127_1382628_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 589.0
HKD2_k127_1382628_2 PFAM alpha beta hydrolase fold K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 458.0
HKD2_k127_1382628_3 SMART Elongator protein 3 MiaB NifB K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 421.0
HKD2_k127_1382628_4 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 380.0
HKD2_k127_1382628_5 Binding-protein-dependent transport system inner membrane component K02050,K15554 - - 0.00000000000000000000000000000000003801 135.0
HKD2_k127_1382628_7 pyridoxamine 5-phosphate - - - 0.00000000003363 68.0
HKD2_k127_1385088_0 B12 binding domain K04034 - 1.21.98.3 6.326e-216 685.0
HKD2_k127_1385088_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 599.0
HKD2_k127_1385088_2 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 455.0
HKD2_k127_1385088_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 364.0
HKD2_k127_1385088_4 [acyl-carrier-protein] S-malonyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 326.0
HKD2_k127_1385088_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 254.0
HKD2_k127_1385088_6 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
HKD2_k127_1385088_7 FabA-like domain K02372 - 4.2.1.59 0.00000001469 62.0
HKD2_k127_1386755_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 1.784e-304 953.0
HKD2_k127_1386755_1 PFAM major facilitator superfamily MFS_1 K08177 - - 1.64e-244 759.0
HKD2_k127_1386755_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000008471 209.0
HKD2_k127_1386755_12 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000000000000000000254 196.0
HKD2_k127_1386755_13 MarR family transcriptional K15973 - - 0.00000000000000000000000000000000000000000000000001539 184.0
HKD2_k127_1386755_14 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000000000000006829 175.0
HKD2_k127_1386755_15 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000002318 163.0
HKD2_k127_1386755_16 response regulator - - - 0.000000000000000000000000000000000000000007564 164.0
HKD2_k127_1386755_17 ATP-independent chaperone mediated protein folding K06006 - - 0.000000000000000000000000000000001765 136.0
HKD2_k127_1386755_2 Histidine kinase - - - 1.305e-212 671.0
HKD2_k127_1386755_22 - - - - 0.000000002715 58.0
HKD2_k127_1386755_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 560.0
HKD2_k127_1386755_5 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 434.0
HKD2_k127_1386755_6 GPR1 FUN34 yaaH family protein K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 394.0
HKD2_k127_1386755_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 393.0
HKD2_k127_1386755_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 331.0
HKD2_k127_1386755_9 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007617 273.0
HKD2_k127_1389277_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0 1560.0
HKD2_k127_1389277_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1065.0
HKD2_k127_1389277_10 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 510.0
HKD2_k127_1389277_11 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 511.0
HKD2_k127_1389277_12 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 458.0
HKD2_k127_1389277_13 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 451.0
HKD2_k127_1389277_14 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 431.0
HKD2_k127_1389277_15 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 407.0
HKD2_k127_1389277_16 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 368.0
HKD2_k127_1389277_18 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009625 256.0
HKD2_k127_1389277_19 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
HKD2_k127_1389277_2 Histidine kinase - - - 2.774e-307 946.0
HKD2_k127_1389277_20 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000001409 213.0
HKD2_k127_1389277_24 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000003023 75.0
HKD2_k127_1389277_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 5.015e-292 899.0
HKD2_k127_1389277_4 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 6.967e-272 844.0
HKD2_k127_1389277_5 response regulator K02481,K07715 - - 1.691e-256 795.0
HKD2_k127_1389277_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771,K04772 - 3.4.21.107 4.921e-254 790.0
HKD2_k127_1389277_7 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 570.0
HKD2_k127_1389277_8 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 562.0
HKD2_k127_1389277_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 542.0
HKD2_k127_139635_0 - - - - 0.0000000000000000000000000000000000000000000001377 186.0
HKD2_k127_139635_1 COGs COG3328 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000003817 141.0
HKD2_k127_139635_2 COGs COG3328 Transposase and inactivated derivatives - - - 0.00000000000000000003619 95.0
HKD2_k127_1401026_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 8.364e-205 639.0
HKD2_k127_1401026_1 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 419.0
HKD2_k127_1401026_11 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0002798 45.0
HKD2_k127_1401026_2 Flavodoxin-like fold K01118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 361.0
HKD2_k127_1401026_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 319.0
HKD2_k127_1401026_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 297.0
HKD2_k127_1401026_5 antibiotic catabolic process K13277,K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005769 268.0
HKD2_k127_1401026_6 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000000000000000000000000000001958 188.0
HKD2_k127_1401026_7 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000003194 162.0
HKD2_k127_1401026_8 fibronectin type III domain protein - - - 0.000000000001025 70.0
HKD2_k127_141119_0 HELICc2 K03722 - 3.6.4.12 0.0 1452.0
HKD2_k127_141119_1 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1211.0
HKD2_k127_141119_10 bacterial-type flagellum-dependent cell motility K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 433.0
HKD2_k127_141119_11 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 401.0
HKD2_k127_141119_12 PFAM Endonuclease exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
HKD2_k127_141119_13 PFAM Phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 368.0
HKD2_k127_141119_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 369.0
HKD2_k127_141119_15 Belongs to the flagella basal body rod proteins family K02391,K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 343.0
HKD2_k127_141119_16 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 353.0
HKD2_k127_141119_17 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 335.0
HKD2_k127_141119_18 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 312.0
HKD2_k127_141119_19 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 301.0
HKD2_k127_141119_2 Flagellar basal body rod protein K02396 - - 6.904e-196 621.0
HKD2_k127_141119_20 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001008 291.0
HKD2_k127_141119_23 Pfam Zn-finger in ubiquitin-hydrolases and other protein K03455 - - 0.000000000000000000000000000000000000000144 154.0
HKD2_k127_141119_24 PFAM flagellar FlbD family protein K02385 - - 0.0000000000000000000000000000000000277 135.0
HKD2_k127_141119_25 PFAM Flagellar protein K02395 - - 0.0000000000000000000000000000001245 127.0
HKD2_k127_141119_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 599.0
HKD2_k127_141119_4 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 576.0
HKD2_k127_141119_5 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 576.0
HKD2_k127_141119_6 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 526.0
HKD2_k127_141119_7 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 468.0
HKD2_k127_141119_8 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 456.0
HKD2_k127_141119_9 Belongs to the flagella basal body rod proteins family K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 448.0
HKD2_k127_1413314_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1590.0
HKD2_k127_1413314_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1254.0
HKD2_k127_1413314_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 604.0
HKD2_k127_1413314_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 482.0
HKD2_k127_1413314_4 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 441.0
HKD2_k127_1413314_5 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000001896 207.0
HKD2_k127_1413314_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000009382 163.0
HKD2_k127_1413314_7 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000001641 108.0
HKD2_k127_1419691_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 513.0
HKD2_k127_1419691_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
HKD2_k127_1419691_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000003087 116.0
HKD2_k127_1419691_3 histidine kinase HAMP region domain protein - - - 0.00003453 46.0
HKD2_k127_1423365_0 Acyl-protein synthetase, LuxE - - - 3.705e-202 632.0
HKD2_k127_1426266_0 Domain of unknown function (DUF4070) - - - 2.414e-246 768.0
HKD2_k127_1426266_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 6.525e-222 694.0
HKD2_k127_1426266_10 Cyclase dehydrase - - - 0.00000000000000000000000000005272 121.0
HKD2_k127_1426266_2 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 517.0
HKD2_k127_1426266_3 PFAM import inner membrane translocase, subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 377.0
HKD2_k127_1426266_4 hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 355.0
HKD2_k127_1426266_5 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 338.0
HKD2_k127_1426266_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 282.0
HKD2_k127_1426266_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000001141 202.0
HKD2_k127_1426266_8 protein-glutamate methylesterase activity K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000003312 184.0
HKD2_k127_1426266_9 PFAM Polyketide cyclase dehydrase K03396 - 4.4.1.22 0.00000000000000000000000000000000000000000000000002742 183.0
HKD2_k127_1431158_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 417.0
HKD2_k127_1431158_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 412.0
HKD2_k127_1431158_2 - - - - 0.000000004265 57.0
HKD2_k127_1431158_3 - - - - 0.0001006 46.0
HKD2_k127_1437790_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.208e-229 725.0
HKD2_k127_1437790_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000002595 215.0
HKD2_k127_14488_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1834.0
HKD2_k127_14488_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 8.623e-212 674.0
HKD2_k127_14488_10 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 379.0
HKD2_k127_14488_11 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 372.0
HKD2_k127_14488_12 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 337.0
HKD2_k127_14488_13 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 320.0
HKD2_k127_14488_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005669 291.0
HKD2_k127_14488_15 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003573 254.0
HKD2_k127_14488_16 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000433 245.0
HKD2_k127_14488_17 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001909 233.0
HKD2_k127_14488_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001144 224.0
HKD2_k127_14488_19 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000345 208.0
HKD2_k127_14488_2 TIGRFAM cytochrome C family protein - - - 3.958e-208 655.0
HKD2_k127_14488_20 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000001996 193.0
HKD2_k127_14488_21 mercury ion transmembrane transporter activity K07089,K07213 - - 0.00000000000000000000000000000000000000000000006363 173.0
HKD2_k127_14488_22 electron transfer activity K05337 - - 0.000000000000000000000000000003005 120.0
HKD2_k127_14488_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 4.522e-205 647.0
HKD2_k127_14488_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 602.0
HKD2_k127_14488_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 576.0
HKD2_k127_14488_6 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 565.0
HKD2_k127_14488_7 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 463.0
HKD2_k127_14488_8 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 463.0
HKD2_k127_1459835_0 penicillin-binding protein K05365,K05366,K21464 - 2.4.1.129,3.4.16.4 1.331e-307 953.0
HKD2_k127_1460427_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1134.0
HKD2_k127_1460427_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 598.0
HKD2_k127_1460427_10 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 364.0
HKD2_k127_1460427_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
HKD2_k127_1460427_12 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003726 255.0
HKD2_k127_1460427_13 phosphorelay signal transduction system K03413 - - 0.000000000000000000000000000000000000000000000000000000005045 201.0
HKD2_k127_1460427_14 Membrane - - - 0.0000000000000000000000000000000000000000000000001344 182.0
HKD2_k127_1460427_15 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000001735 170.0
HKD2_k127_1460427_16 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000001214 165.0
HKD2_k127_1460427_2 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 572.0
HKD2_k127_1460427_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 530.0
HKD2_k127_1460427_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 473.0
HKD2_k127_1460427_5 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 469.0
HKD2_k127_1460427_6 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 446.0
HKD2_k127_1460427_7 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 443.0
HKD2_k127_1460427_8 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 439.0
HKD2_k127_1460427_9 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 393.0
HKD2_k127_1463090_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 3.46e-202 634.0
HKD2_k127_1463090_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 523.0
HKD2_k127_1463090_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 365.0
HKD2_k127_1463090_3 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 349.0
HKD2_k127_1463090_5 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000004116 175.0
HKD2_k127_1463090_6 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000003336 169.0
HKD2_k127_1470212_0 type IV pilus assembly PilZ - - - 0.0 1039.0
HKD2_k127_1470212_1 metal-dependent phosphohydrolase HD region - - - 2.135e-312 966.0
HKD2_k127_1470212_2 Histidine kinase - - - 1.361e-274 861.0
HKD2_k127_1470212_3 Sensor diguanylate cyclase, GAF domain-containing - - - 3.957e-253 800.0
HKD2_k127_1470212_4 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 573.0
HKD2_k127_1475554_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 468.0
HKD2_k127_1475554_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 332.0
HKD2_k127_1475554_2 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000001749 198.0
HKD2_k127_1475554_3 YMGG-like Gly-zipper - - - 0.0000000000000000000000000000000000000002844 154.0
HKD2_k127_1475554_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000003915 154.0
HKD2_k127_1475554_5 - - - - 0.00000000000000000000000000000000003473 138.0
HKD2_k127_1477317_0 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 398.0
HKD2_k127_1477317_1 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 345.0
HKD2_k127_1481477_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 6.412e-252 780.0
HKD2_k127_1481477_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.833e-232 723.0
HKD2_k127_1481477_2 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 353.0
HKD2_k127_1481477_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000005047 190.0
HKD2_k127_1483439_0 Methionine biosynthesis protein MetW - - - 0.000000000001483 76.0
HKD2_k127_1483439_1 DDE superfamily endonuclease - - - 0.00001791 49.0
HKD2_k127_1483883_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1062.0
HKD2_k127_1483883_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1007.0
HKD2_k127_1483883_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 282.0
HKD2_k127_1483883_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004975 286.0
HKD2_k127_1483883_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
HKD2_k127_1483883_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000001748 211.0
HKD2_k127_1483883_14 Prokaryotic E2 family C - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001129 211.0
HKD2_k127_1483883_15 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000002743 179.0
HKD2_k127_1483883_16 peptidoglycan binding - - - 0.0000000000000000000000000000000000000004271 156.0
HKD2_k127_1483883_18 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000005981 108.0
HKD2_k127_1483883_19 - - - - 0.000000000000001087 84.0
HKD2_k127_1483883_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 6.317e-253 788.0
HKD2_k127_1483883_20 Protein of Unknown function (DUF2604) - - - 0.000000000000003262 78.0
HKD2_k127_1483883_21 Predicted metal binding domain - - - 0.000000003716 66.0
HKD2_k127_1483883_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.952e-249 773.0
HKD2_k127_1483883_4 Sensor protein, DUF3365, HAMP and PAS domain-containing, heme-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 560.0
HKD2_k127_1483883_5 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 471.0
HKD2_k127_1483883_6 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 391.0
HKD2_k127_1483883_7 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 367.0
HKD2_k127_1483883_8 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 328.0
HKD2_k127_1483883_9 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 303.0
HKD2_k127_1493672_0 DEAD_2 K10844 - 3.6.4.12 1.709e-308 957.0
HKD2_k127_1493672_1 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 301.0
HKD2_k127_1493672_2 cytochrome - - - 0.0000000000000000000000000000000000000000002389 161.0
HKD2_k127_1494775_0 PFAM natural resistance-associated macrophage protein - - - 6.622e-200 630.0
HKD2_k127_1494775_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 560.0
HKD2_k127_1494775_2 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 496.0
HKD2_k127_1494775_3 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 342.0
HKD2_k127_1494775_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000003679 144.0
HKD2_k127_1494775_7 - - - - 0.00005036 45.0
HKD2_k127_1495819_0 Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 445.0
HKD2_k127_1495819_1 required for the transposition of insertion element IS2404 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 374.0
HKD2_k127_1495819_2 Transposase IS66 family - - - 0.000000000000000000000000000001338 122.0
HKD2_k127_1495819_3 Caspase domain - - - 0.0000000000000000000000357 107.0
HKD2_k127_1498076_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000002856 185.0
HKD2_k127_1498976_0 - - - - 0.000000000000000000000000000002506 120.0
HKD2_k127_1498976_1 - - - - 0.000000000000000000007392 95.0
HKD2_k127_1498976_3 - - - - 0.000000000001516 68.0
HKD2_k127_1498976_4 - - - - 0.0000004342 53.0
HKD2_k127_1498976_5 - - - - 0.000001045 50.0
HKD2_k127_1502422_0 PFAM Carboxylyase-related protein K03182 - 4.1.1.98 0.0 1118.0
HKD2_k127_1502422_1 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 411.0
HKD2_k127_1502422_2 PFAM histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000000000000000002251 203.0
HKD2_k127_1502422_3 Domain of unknown function (DUF4124) - - - 0.0000000000000001926 80.0
HKD2_k127_1504149_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 507.0
HKD2_k127_1504149_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 500.0
HKD2_k127_1504149_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 458.0
HKD2_k127_1504149_3 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 455.0
HKD2_k127_1504149_4 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 407.0
HKD2_k127_1504149_5 Psort location CytoplasmicMembrane, score K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 291.0
HKD2_k127_1504149_6 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000009693 192.0
HKD2_k127_1530265_0 Aconitate hydratase 1 K01681 - 4.2.1.3 0.0 1275.0
HKD2_k127_1530265_1 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.0 1241.0
HKD2_k127_1530265_10 Sigma-54 factor interaction domain-containing protein - - - 2.194e-226 708.0
HKD2_k127_1530265_11 Histidine kinase - - - 1.021e-225 711.0
HKD2_k127_1530265_12 Pyridine nucleotide-disulphide oxidoreductase - - - 8.159e-222 689.0
HKD2_k127_1530265_13 TonB-dependent Receptor Plug K16092 - - 6.242e-215 684.0
HKD2_k127_1530265_14 AIR synthase related protein domain protein K01933 - 6.3.3.1 5.28e-214 666.0
HKD2_k127_1530265_15 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 5.508e-209 651.0
HKD2_k127_1530265_16 SMART Elongator protein 3 MiaB NifB - - - 2.27e-205 648.0
HKD2_k127_1530265_17 belongs to the CobB CobQ family K06873 - - 5.285e-205 642.0
HKD2_k127_1530265_18 CHASE4 domain - - - 1.554e-196 637.0
HKD2_k127_1530265_19 Methyl-transferase K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 618.0
HKD2_k127_1530265_2 Histidine kinase - - - 0.0 1167.0
HKD2_k127_1530265_20 Response receiver-modulated cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 579.0
HKD2_k127_1530265_21 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 571.0
HKD2_k127_1530265_22 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 580.0
HKD2_k127_1530265_23 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 588.0
HKD2_k127_1530265_24 Lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 562.0
HKD2_k127_1530265_25 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 551.0
HKD2_k127_1530265_26 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 541.0
HKD2_k127_1530265_27 AAA domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 521.0
HKD2_k127_1530265_28 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 519.0
HKD2_k127_1530265_29 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 496.0
HKD2_k127_1530265_3 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 6.094e-312 969.0
HKD2_k127_1530265_30 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 481.0
HKD2_k127_1530265_31 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 461.0
HKD2_k127_1530265_32 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
HKD2_k127_1530265_33 Response receiver sensor diguanylate cyclase, PAS domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 463.0
HKD2_k127_1530265_34 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 450.0
HKD2_k127_1530265_35 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 413.0
HKD2_k127_1530265_36 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 409.0
HKD2_k127_1530265_37 sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 421.0
HKD2_k127_1530265_38 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007887 389.0
HKD2_k127_1530265_39 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 384.0
HKD2_k127_1530265_4 ATP-binding region ATPase domain protein K03407,K13490 - 2.7.13.3 6.612e-308 955.0
HKD2_k127_1530265_40 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 353.0
HKD2_k127_1530265_41 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 351.0
HKD2_k127_1530265_42 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 347.0
HKD2_k127_1530265_43 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 337.0
HKD2_k127_1530265_44 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 331.0
HKD2_k127_1530265_45 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 347.0
HKD2_k127_1530265_46 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 329.0
HKD2_k127_1530265_47 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 330.0
HKD2_k127_1530265_48 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 306.0
HKD2_k127_1530265_49 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 304.0
HKD2_k127_1530265_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 1.492e-291 909.0
HKD2_k127_1530265_50 Membrane-associated sensor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 323.0
HKD2_k127_1530265_51 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 298.0
HKD2_k127_1530265_52 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 299.0
HKD2_k127_1530265_53 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007748 292.0
HKD2_k127_1530265_54 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 293.0
HKD2_k127_1530265_55 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002419 270.0
HKD2_k127_1530265_56 Metal-dependent phosphohydrolase K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
HKD2_k127_1530265_57 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000006199 238.0
HKD2_k127_1530265_58 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
HKD2_k127_1530265_59 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000000000000000000000000000000000000000000000000000008207 246.0
HKD2_k127_1530265_6 Sodium:sulfate symporter transmembrane region K14445 - - 6.757e-269 832.0
HKD2_k127_1530265_60 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000002599 199.0
HKD2_k127_1530265_61 dnak suppressor protein K06204 - - 0.00000000000000000000000000000000000000000000000000002459 191.0
HKD2_k127_1530265_62 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000001458 187.0
HKD2_k127_1530265_63 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000396 186.0
HKD2_k127_1530265_64 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000005617 183.0
HKD2_k127_1530265_65 YtxH-like protein - - - 0.0000000000000000000000000000000000000008378 151.0
HKD2_k127_1530265_66 protein conserved in bacteria - - - 0.0000000000000000000000000000007873 126.0
HKD2_k127_1530265_67 homolog of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.00000000000000000000000000006955 119.0
HKD2_k127_1530265_68 SlyX K03745 - - 0.00000000000000000000000003741 108.0
HKD2_k127_1530265_69 YtxH-like protein - - - 0.000000000000000000000000205 107.0
HKD2_k127_1530265_7 response regulator - - - 4.204e-262 812.0
HKD2_k127_1530265_72 Dienelactone hydrolase family K06889 - - 0.00000001568 56.0
HKD2_k127_1530265_73 Alpha/beta hydrolase family - - - 0.000000261 53.0
HKD2_k127_1530265_74 PFAM WD40 domain protein beta Propeller - - - 0.0000229 48.0
HKD2_k127_1530265_75 - - - - 0.0005772 48.0
HKD2_k127_1530265_8 alpha amylase, catalytic region - - - 4.467e-242 757.0
HKD2_k127_1530265_9 SurA N-terminal domain K03770 - 5.2.1.8 1.837e-239 750.0
HKD2_k127_1532767_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 436.0
HKD2_k127_1532767_1 PFAM Nitroreductase - - - 0.00000000000000007795 81.0
HKD2_k127_1533951_0 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1213.0
HKD2_k127_1533951_1 4Fe-4S dicluster domain - - - 0.0 1118.0
HKD2_k127_1533951_10 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 462.0
HKD2_k127_1533951_11 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 406.0
HKD2_k127_1533951_12 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 383.0
HKD2_k127_1533951_13 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 379.0
HKD2_k127_1533951_14 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 315.0
HKD2_k127_1533951_15 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 305.0
HKD2_k127_1533951_16 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 298.0
HKD2_k127_1533951_17 IMP dehydrogenase activity K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002236 252.0
HKD2_k127_1533951_18 THUMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000001763 239.0
HKD2_k127_1533951_19 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000192 244.0
HKD2_k127_1533951_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 6.421e-263 816.0
HKD2_k127_1533951_20 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000009442 227.0
HKD2_k127_1533951_21 PFAM DivIVA family protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000000001695 215.0
HKD2_k127_1533951_22 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000000000000004952 206.0
HKD2_k127_1533951_23 YGGT family K02221 - - 0.000000000000000000000000000000000000000000000000003553 183.0
HKD2_k127_1533951_24 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000005087 183.0
HKD2_k127_1533951_25 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000000000000002887 178.0
HKD2_k127_1533951_26 Sulfatase - - - 0.000000000000000000000000000000000000000000000001419 194.0
HKD2_k127_1533951_27 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000000000000000000000002871 167.0
HKD2_k127_1533951_28 Cache 3/Cache 2 fusion domain - - - 0.0000000000000000000000000000000000000000002329 179.0
HKD2_k127_1533951_29 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000003745 160.0
HKD2_k127_1533951_3 Ammonium Transporter K03320 - - 4.185e-261 812.0
HKD2_k127_1533951_30 Putative regulatory protein - - - 0.00000000000000000000000000000000000001816 144.0
HKD2_k127_1533951_31 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000383 142.0
HKD2_k127_1533951_32 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000006997 120.0
HKD2_k127_1533951_33 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000001105 109.0
HKD2_k127_1533951_4 Ammonium Transporter Family K03320 - - 2.784e-246 771.0
HKD2_k127_1533951_5 electron transfer flavoprotein, alpha subunit K03522 - - 1.571e-238 743.0
HKD2_k127_1533951_6 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 530.0
HKD2_k127_1533951_7 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 546.0
HKD2_k127_1533951_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 509.0
HKD2_k127_1533951_9 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD2_k127_1554244_0 GGDEF domain containing protein - - - 0.0 1223.0
HKD2_k127_1554244_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 5.777e-240 751.0
HKD2_k127_1554244_10 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000002711 227.0
HKD2_k127_1554244_11 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.0000000000000000000000000000000000000000000000000000000000001872 220.0
HKD2_k127_1554244_2 PFAM Xanthine uracil vitamin C permease K02824 - - 5.466e-227 715.0
HKD2_k127_1554244_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 564.0
HKD2_k127_1554244_4 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 560.0
HKD2_k127_1554244_5 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 415.0
HKD2_k127_1554244_6 PFAM Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 379.0
HKD2_k127_1554244_7 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 371.0
HKD2_k127_1554244_8 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 335.0
HKD2_k127_1554244_9 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006961 269.0
HKD2_k127_156265_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 322.0
HKD2_k127_156265_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000002118 222.0
HKD2_k127_1567509_0 Transposase zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 389.0
HKD2_k127_1567509_1 PFAM Transposase IS66 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 325.0
HKD2_k127_1567509_2 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000005692 135.0
HKD2_k127_1572536_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000003264 126.0
HKD2_k127_1592313_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1034.0
HKD2_k127_1592313_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 7e-323 994.0
HKD2_k127_1592313_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 396.0
HKD2_k127_1592313_3 phosphorelay signal transduction system K15012 - - 0.000000000000000000000000000000000000000000000000000000002531 213.0
HKD2_k127_1592313_4 Helix-turn-helix domain - - - 0.00000000000000000000000000001042 120.0
HKD2_k127_1600012_0 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001349 284.0
HKD2_k127_1600012_1 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000002365 68.0
HKD2_k127_1613158_0 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 297.0
HKD2_k127_1621705_0 Histidine kinase HAMP - - - 3.353e-307 953.0
HKD2_k127_1621705_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 6.124e-246 768.0
HKD2_k127_1621705_2 B12 binding domain - - - 4.143e-236 736.0
HKD2_k127_1621705_4 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.00000000000000000000000000000000000000000000000000000002564 199.0
HKD2_k127_1640948_0 Belongs to the glutamate synthase family K22083 - 2.1.1.21 1.66e-315 970.0
HKD2_k127_1640948_1 Glutamine amidotransferases class-II - - - 1.095e-217 678.0
HKD2_k127_1640948_2 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 4.543e-217 679.0
HKD2_k127_1640948_3 PFAM glutamate synthase alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 426.0
HKD2_k127_1640948_4 4Fe-4S dicluster domain K00196,K05796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 290.0
HKD2_k127_1640948_5 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.0000000000000000000000000000000000000001143 153.0
HKD2_k127_1649237_0 response to hydroperoxide K03878 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030425,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0033194,GO:0034622,GO:0034641,GO:0036477,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0097447,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:0120038,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002697 199.0
HKD2_k127_1649237_1 response to hydroperoxide K03878 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030425,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0033194,GO:0034622,GO:0034641,GO:0036477,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0097447,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:0120038,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000005874 128.0
HKD2_k127_1649237_2 response to hydroperoxide K03878 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030425,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0033194,GO:0034622,GO:0034641,GO:0036477,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0097447,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:0120038,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000001167 88.0
HKD2_k127_1649237_3 response to hydroperoxide K03878 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0007005,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010033,GO:0010257,GO:0014070,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030425,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032981,GO:0032991,GO:0033108,GO:0033194,GO:0034622,GO:0034641,GO:0036477,GO:0042221,GO:0042493,GO:0042773,GO:0042775,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044297,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044463,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0050896,GO:0055086,GO:0055114,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072521,GO:0097447,GO:0097458,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0120025,GO:0120038,GO:1901135,GO:1901360,GO:1901564,GO:1901700,GO:1902494,GO:1990204 1.6.5.3 0.0000000006665 59.0
HKD2_k127_1661276_0 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 2.048e-211 665.0
HKD2_k127_1662230_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009979 473.0
HKD2_k127_1678486_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 5.894e-282 873.0
HKD2_k127_1678486_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 446.0
HKD2_k127_1678486_2 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 377.0
HKD2_k127_1678486_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000005296 227.0
HKD2_k127_1689289_0 Polysaccharide biosynthesis protein CapD - - - 0.0 1039.0
HKD2_k127_1689289_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 7.014e-264 826.0
HKD2_k127_1689289_2 Capsule assembly protein Wzi - - - 5.283e-256 799.0
HKD2_k127_1689289_3 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 465.0
HKD2_k127_1689289_4 Catalyzes the synthesis of activated sulfate K00860,K00955,K00958 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 308.0
HKD2_k127_1689289_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000004398 190.0
HKD2_k127_1695841_0 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 359.0
HKD2_k127_1708826_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 1.422e-217 677.0
HKD2_k127_1708826_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 585.0
HKD2_k127_1708826_10 PFAM PHP domain protein K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 306.0
HKD2_k127_1708826_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000000000000000000000000000000000000001034 186.0
HKD2_k127_1708826_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000001944 186.0
HKD2_k127_1708826_13 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000000000000000000000259 183.0
HKD2_k127_1708826_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000002629 174.0
HKD2_k127_1708826_16 Carboxypeptidase regulatory-like domain - - - 0.0001179 51.0
HKD2_k127_1708826_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 576.0
HKD2_k127_1708826_3 Nickel-dependent hydrogenase large subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 538.0
HKD2_k127_1708826_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 464.0
HKD2_k127_1708826_5 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 447.0
HKD2_k127_1708826_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 453.0
HKD2_k127_1708826_7 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 386.0
HKD2_k127_1708826_8 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 344.0
HKD2_k127_1708826_9 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 322.0
HKD2_k127_1714405_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0 1021.0
HKD2_k127_1714405_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.5e-293 899.0
HKD2_k127_1714405_10 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 519.0
HKD2_k127_1714405_11 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 496.0
HKD2_k127_1714405_12 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 484.0
HKD2_k127_1714405_13 TIGRFAM phosphate ABC transporter K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 465.0
HKD2_k127_1714405_14 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 435.0
HKD2_k127_1714405_15 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 415.0
HKD2_k127_1714405_16 (EAL) domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 415.0
HKD2_k127_1714405_17 response regulator K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 362.0
HKD2_k127_1714405_18 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 359.0
HKD2_k127_1714405_19 response regulator K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 342.0
HKD2_k127_1714405_2 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 1.77e-254 801.0
HKD2_k127_1714405_20 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 297.0
HKD2_k127_1714405_21 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003583 280.0
HKD2_k127_1714405_22 sigma factor antagonist activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001988 288.0
HKD2_k127_1714405_23 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001651 269.0
HKD2_k127_1714405_24 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004206 268.0
HKD2_k127_1714405_25 Universal stress protein K06149 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003034 257.0
HKD2_k127_1714405_26 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006123 243.0
HKD2_k127_1714405_27 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000000000000000000002626 206.0
HKD2_k127_1714405_28 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000002813 193.0
HKD2_k127_1714405_29 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.000000000000000000000000000000000000008456 151.0
HKD2_k127_1714405_3 FAD dependent oxidoreductase K07137 - - 5.735e-252 785.0
HKD2_k127_1714405_30 antisigma factor binding - - - 0.000000000000000000000000001587 117.0
HKD2_k127_1714405_31 Prolipoprotein diacylglyceryl transferase - - - 0.0000000000000000000008901 98.0
HKD2_k127_1714405_33 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000002059 84.0
HKD2_k127_1714405_36 transmembrane signaling receptor activity K03406 - - 0.0005623 44.0
HKD2_k127_1714405_4 histidine kinase - - - 1.739e-222 693.0
HKD2_k127_1714405_5 peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 5.459e-198 623.0
HKD2_k127_1714405_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 3.278e-196 617.0
HKD2_k127_1714405_7 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 581.0
HKD2_k127_1714405_8 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 580.0
HKD2_k127_1714405_9 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 553.0
HKD2_k127_1721241_0 cellulose binding - - - 1.548e-297 944.0
HKD2_k127_1721241_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.677e-238 741.0
HKD2_k127_1721241_2 NAD(P)-binding Rossmann-like domain - - - 4.925e-196 620.0
HKD2_k127_1721241_3 response regulator K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 312.0
HKD2_k127_1721241_5 Phosphopantetheine attachment site K02078 - - 0.000000000000000000000000001919 115.0
HKD2_k127_1753096_0 ABC transporter C-terminal domain K15738 - - 0.0 1084.0
HKD2_k127_1753096_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.432e-232 726.0
HKD2_k127_1753096_10 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 284.0
HKD2_k127_1753096_11 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 251.0
HKD2_k127_1753096_12 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000000000000000000000000000005454 222.0
HKD2_k127_1753096_13 - - - - 0.00000000000000000000000000000000000000000000000000000001473 203.0
HKD2_k127_1753096_15 Protein of unknown function (DUF1294) - - - 0.000000000000000000000000001891 114.0
HKD2_k127_1753096_17 histidine kinase HAMP region domain protein K03406 - - 0.000000000000168 71.0
HKD2_k127_1753096_2 Pro-kumamolisin, activation domain K08677 - - 3.622e-227 736.0
HKD2_k127_1753096_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 1.341e-206 644.0
HKD2_k127_1753096_4 Formate/nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 429.0
HKD2_k127_1753096_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 430.0
HKD2_k127_1753096_6 PFAM Chromosomal replication initiator, DnaA K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 380.0
HKD2_k127_1753096_7 alpha beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
HKD2_k127_1753096_8 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 336.0
HKD2_k127_1753096_9 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 297.0
HKD2_k127_1768318_0 MMPL family K07003 - - 0.0 1025.0
HKD2_k127_1768318_1 Aromatic amino acid lyase K01745 - 4.3.1.3 4.929e-302 930.0
HKD2_k127_1768318_10 PFAM Beta-ketoacyl synthase K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 429.0
HKD2_k127_1768318_11 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 416.0
HKD2_k127_1768318_12 PFAM FAD dependent oxidoreductase K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 391.0
HKD2_k127_1768318_13 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 352.0
HKD2_k127_1768318_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 322.0
HKD2_k127_1768318_15 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000447 282.0
HKD2_k127_1768318_16 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000001269 241.0
HKD2_k127_1768318_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001911 267.0
HKD2_k127_1768318_18 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000006386 230.0
HKD2_k127_1768318_19 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000004131 212.0
HKD2_k127_1768318_2 SMART Elongator protein 3 MiaB NifB - - - 1.349e-275 852.0
HKD2_k127_1768318_20 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000000000000000000004136 211.0
HKD2_k127_1768318_21 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000123 177.0
HKD2_k127_1768318_22 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000003726 154.0
HKD2_k127_1768318_23 PFAM Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000001024 153.0
HKD2_k127_1768318_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000006246 143.0
HKD2_k127_1768318_25 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000002997 133.0
HKD2_k127_1768318_26 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000003149 112.0
HKD2_k127_1768318_27 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000005813 108.0
HKD2_k127_1768318_28 PFAM Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA FabZ K02372 - 4.2.1.59 0.000000000009996 70.0
HKD2_k127_1768318_29 PFAM Lipid A 3-O-deacylase-related - - - 0.0000000006779 64.0
HKD2_k127_1768318_3 B12 binding domain - - - 1.856e-228 711.0
HKD2_k127_1768318_30 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000695 46.0
HKD2_k127_1768318_4 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 1.172e-217 679.0
HKD2_k127_1768318_5 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 1.295e-213 670.0
HKD2_k127_1768318_6 SMART Elongator protein 3 MiaB NifB - - - 3.744e-204 644.0
HKD2_k127_1768318_7 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 615.0
HKD2_k127_1768318_8 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 599.0
HKD2_k127_1768318_9 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 512.0
HKD2_k127_1801855_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1389.0
HKD2_k127_1801855_1 aminotransferase class I and II - - - 1.764e-255 793.0
HKD2_k127_1801855_2 PFAM ABC transporter K05776 - - 7.727e-227 711.0
HKD2_k127_1801855_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
HKD2_k127_1801855_4 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 388.0
HKD2_k127_1801855_5 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 370.0
HKD2_k127_1801855_6 HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000003245 230.0
HKD2_k127_1801855_8 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000001999 165.0
HKD2_k127_1801855_9 PFAM DSBA oxidoreductase - - - 0.000000000000007493 85.0
HKD2_k127_184620_0 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 0.0 1565.0
HKD2_k127_184620_1 Pro-kumamolisin, activation domain K08677 - - 0.000000000000000000003043 98.0
HKD2_k127_1872705_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 0.0 1469.0
HKD2_k127_1872705_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.007e-257 859.0
HKD2_k127_1872705_2 PFAM Aldehyde ferredoxin oxidoreductase - - - 4.153e-219 694.0
HKD2_k127_1872705_3 Aminotransferase class-III K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 575.0
HKD2_k127_1872705_4 Amino acid permease K03294,K14052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 481.0
HKD2_k127_1872705_5 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 334.0
HKD2_k127_1872705_6 PFAM RNA polymerase sigma factor 54, interaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 331.0
HKD2_k127_1889583_0 ORF located using Blastx - - - 0.000000000001243 70.0
HKD2_k127_1889583_1 COG NOG38524 non supervised orthologous group - - - 0.00000000008652 64.0
HKD2_k127_1942312_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0 1002.0
HKD2_k127_1942312_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.307e-292 901.0
HKD2_k127_1942312_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 300.0
HKD2_k127_1942312_3 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002713 278.0
HKD2_k127_1942312_5 - - - - 0.0009594 44.0
HKD2_k127_1973833_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.221e-207 647.0
HKD2_k127_1975932_0 elongation factor Tu domain 2 protein K02355 - - 0.0 1240.0
HKD2_k127_1975932_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 513.0
HKD2_k127_1975932_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 476.0
HKD2_k127_1975932_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 451.0
HKD2_k127_1975932_4 12 heme-binding sites - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 358.0
HKD2_k127_2002798_0 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 388.0
HKD2_k127_2002798_1 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 312.0
HKD2_k127_2008528_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1487.0
HKD2_k127_2008528_1 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.0 1079.0
HKD2_k127_2008528_2 Histidine kinase K07711 - 2.7.13.3 0.0 1049.0
HKD2_k127_2008528_3 deoxyhypusine monooxygenase activity - - - 5.761e-207 654.0
HKD2_k127_2008528_4 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 559.0
HKD2_k127_2008528_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 562.0
HKD2_k127_2008528_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 430.0
HKD2_k127_2008528_7 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001225 298.0
HKD2_k127_2008528_8 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 267.0
HKD2_k127_2008528_9 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000005267 237.0
HKD2_k127_200940_0 - - - - 0.000000000000000373 80.0
HKD2_k127_200940_3 - - - - 0.000408 43.0
HKD2_k127_2023561_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 6.921e-254 792.0
HKD2_k127_2023561_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 445.0
HKD2_k127_2023561_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.00000000000000000000000119 117.0
HKD2_k127_203945_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000003051 182.0
HKD2_k127_203945_1 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000001951 140.0
HKD2_k127_203945_2 Protein of unknown function (DUF3761) - - - 0.00000000000000004579 88.0
HKD2_k127_2040035_0 Histidine kinase - - - 1.561e-275 863.0
HKD2_k127_2040035_1 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 342.0
HKD2_k127_2040035_2 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 331.0
HKD2_k127_2040035_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001392 234.0
HKD2_k127_2040035_4 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000001238 221.0
HKD2_k127_2040035_5 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000000000000001265 175.0
HKD2_k127_2058015_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005379 239.0
HKD2_k127_2058015_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000006443 224.0
HKD2_k127_2058015_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000001609 157.0
HKD2_k127_2058015_3 Glycosyltransferase like family 2 - - - 0.000001989 50.0
HKD2_k127_2085125_0 Ompa motb domain protein - - - 0.0 2430.0
HKD2_k127_2085125_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1469.0
HKD2_k127_2085125_10 Protein conserved in bacteria - - - 9.861e-200 634.0
HKD2_k127_2085125_11 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 563.0
HKD2_k127_2085125_12 PFAM Peptidase C13 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 565.0
HKD2_k127_2085125_13 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 481.0
HKD2_k127_2085125_14 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 465.0
HKD2_k127_2085125_15 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 453.0
HKD2_k127_2085125_16 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 429.0
HKD2_k127_2085125_17 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 399.0
HKD2_k127_2085125_18 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 365.0
HKD2_k127_2085125_19 PFAM Maf family protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 309.0
HKD2_k127_2085125_2 ABC transporter K06158 - - 3.46e-321 987.0
HKD2_k127_2085125_20 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000007707 217.0
HKD2_k127_2085125_21 SMART helix-turn-helix domain protein K18831 - - 0.00000000000000000000000000000000000000000000000000002684 190.0
HKD2_k127_2085125_22 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000002043 177.0
HKD2_k127_2085125_23 transcription factor binding - - - 0.0000000000000000000000000000000000000000000000002771 183.0
HKD2_k127_2085125_24 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000000000000000000000001134 163.0
HKD2_k127_2085125_27 response regulator - - - 0.0000000000000000000007647 106.0
HKD2_k127_2085125_28 Protein of unknown function (DUF2971) - - - 0.000000000000002171 87.0
HKD2_k127_2085125_3 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 4.809e-268 828.0
HKD2_k127_2085125_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.063e-263 822.0
HKD2_k127_2085125_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 1.062e-252 782.0
HKD2_k127_2085125_6 Domain of unknown function (DUF4070) - - - 1.519e-251 785.0
HKD2_k127_2085125_7 Peptidase U62 modulator of DNA gyrase K03568 - - 1.311e-248 772.0
HKD2_k127_2085125_8 PFAM peptidase U32 K08303 - - 9.009e-210 662.0
HKD2_k127_2085125_9 PFAM peptidase M16 domain protein - - - 4.354e-204 643.0
HKD2_k127_210646_0 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 2.149e-199 627.0
HKD2_k127_210646_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 564.0
HKD2_k127_210646_2 B12 binding domain - - - 0.000000000000000000000000000006821 119.0
HKD2_k127_210927_0 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000006855 236.0
HKD2_k127_210927_1 DDE superfamily endonuclease - - - 0.0000000000000000008298 87.0
HKD2_k127_216841_0 AsmA-like C-terminal region - - - 0.0 1311.0
HKD2_k127_216841_1 histidine kinase, HAMP K13598 - 2.7.13.3 0.0 1244.0
HKD2_k127_216841_10 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 8.776e-264 816.0
HKD2_k127_216841_11 SMART Elongator protein 3 MiaB NifB - - - 2.118e-263 821.0
HKD2_k127_216841_12 AMP-binding enzyme K01897 - 6.2.1.3 5.202e-242 763.0
HKD2_k127_216841_13 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 2.506e-218 686.0
HKD2_k127_216841_14 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 1.612e-202 636.0
HKD2_k127_216841_15 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 3.608e-197 652.0
HKD2_k127_216841_16 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 594.0
HKD2_k127_216841_17 NAD(P)H-binding K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 586.0
HKD2_k127_216841_18 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 583.0
HKD2_k127_216841_19 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 546.0
HKD2_k127_216841_2 thiolester hydrolase activity - - - 0.0 1086.0
HKD2_k127_216841_20 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 546.0
HKD2_k127_216841_21 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 517.0
HKD2_k127_216841_22 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 518.0
HKD2_k127_216841_23 Domains LysM, LysM, NLPC_P60 K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 508.0
HKD2_k127_216841_24 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 505.0
HKD2_k127_216841_25 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 440.0
HKD2_k127_216841_26 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 442.0
HKD2_k127_216841_27 PFAM YdjC family protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 438.0
HKD2_k127_216841_28 COGs COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 441.0
HKD2_k127_216841_29 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 410.0
HKD2_k127_216841_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0 1069.0
HKD2_k127_216841_30 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 351.0
HKD2_k127_216841_31 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 314.0
HKD2_k127_216841_32 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 287.0
HKD2_k127_216841_33 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 299.0
HKD2_k127_216841_34 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007026 278.0
HKD2_k127_216841_35 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000007933 266.0
HKD2_k127_216841_36 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009573 252.0
HKD2_k127_216841_37 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
HKD2_k127_216841_38 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001792 246.0
HKD2_k127_216841_39 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000000000000005247 226.0
HKD2_k127_216841_4 General secretory system II, protein E domain protein K02454 - - 0.0 1054.0
HKD2_k127_216841_40 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000001539 207.0
HKD2_k127_216841_41 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000002702 200.0
HKD2_k127_216841_42 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000002152 149.0
HKD2_k127_216841_43 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000002701 143.0
HKD2_k127_216841_44 - - - - 0.00000000000000000000000000000001592 132.0
HKD2_k127_216841_46 - - - - 0.00000000000000000000001273 103.0
HKD2_k127_216841_47 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0043610,GO:0044424,GO:0044464,GO:0050789,GO:0065007 - 0.0000000000000001193 83.0
HKD2_k127_216841_48 Response regulator, receiver - - - 0.0000000000000002255 79.0
HKD2_k127_216841_49 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000007535 68.0
HKD2_k127_216841_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 2.006e-305 943.0
HKD2_k127_216841_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.75e-292 902.0
HKD2_k127_216841_7 ABC1 family K03688 - - 3.125e-283 882.0
HKD2_k127_216841_8 SMART Elongator protein 3 MiaB NifB - - - 1.293e-277 856.0
HKD2_k127_216841_9 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 7.063e-264 818.0
HKD2_k127_2197265_0 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 591.0
HKD2_k127_2197265_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00003134 48.0
HKD2_k127_222505_0 Protein of unknown function (DUF1566) - - - 0.00000000000000000002459 104.0
HKD2_k127_222505_1 PKD domain containing protein - - - 0.0000000006372 71.0
HKD2_k127_22538_0 Histidine kinase A domain protein - - - 0.0 1086.0
HKD2_k127_22538_1 Putative exonuclease, RdgC K03554 - - 1.914e-226 706.0
HKD2_k127_22538_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 603.0
HKD2_k127_22538_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 572.0
HKD2_k127_22538_4 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 538.0
HKD2_k127_22538_5 PFAM ABC transporter K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 529.0
HKD2_k127_22538_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000002627 238.0
HKD2_k127_22538_7 PFAM Metal-dependent hydrolase HDOD - - - 0.000003426 52.0
HKD2_k127_22538_9 protein histidine kinase activity K07315,K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.0006363 46.0
HKD2_k127_2263616_0 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 455.0
HKD2_k127_2263616_1 PFAM integrase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002954 254.0
HKD2_k127_22818_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000003512 243.0
HKD2_k127_22818_1 Transposase - - - 0.00000000000000000000000000000000008588 139.0
HKD2_k127_22818_2 Multicopper oxidase - - - 0.000001828 51.0
HKD2_k127_234548_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 509.0
HKD2_k127_234548_1 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
HKD2_k127_234548_2 HisKA, HATPase_c - - - 0.000000000000000000000000000000000000003182 148.0
HKD2_k127_239748_0 Rhodopirellula transposase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 433.0
HKD2_k127_239748_1 Rhodopirellula transposase DDE domain - - - 0.000002738 50.0
HKD2_k127_240205_0 Glycosyl hydrolases family 25 - - - 0.00000000000000000000000000000000000000000001068 170.0
HKD2_k127_240205_1 Phage integrase family - - - 0.000000000000000000000000000000000000001261 151.0
HKD2_k127_240205_2 - - - - 0.0000000000001383 72.0
HKD2_k127_240205_4 - - - - 0.0000000002422 65.0
HKD2_k127_240205_5 Collagen triple helix repeat protein - - - 0.00004431 56.0
HKD2_k127_2410782_0 Actin K05692 GO:0000003,GO:0000228,GO:0000278,GO:0000281,GO:0000785,GO:0000790,GO:0000910,GO:0003006,GO:0003674,GO:0005198,GO:0005200,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005856,GO:0005884,GO:0005886,GO:0005912,GO:0005924,GO:0005925,GO:0006325,GO:0006338,GO:0006996,GO:0007010,GO:0007049,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007291,GO:0007349,GO:0008104,GO:0008150,GO:0009653,GO:0009987,GO:0015629,GO:0016020,GO:0016043,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030054,GO:0030055,GO:0030154,GO:0031011,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032507,GO:0032991,GO:0033036,GO:0033202,GO:0034613,GO:0035060,GO:0035148,GO:0035239,GO:0035295,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044703,GO:0045185,GO:0048232,GO:0048468,GO:0048515,GO:0048609,GO:0048646,GO:0048856,GO:0048869,GO:0051179,GO:0051235,GO:0051276,GO:0051301,GO:0051641,GO:0051651,GO:0051704,GO:0061640,GO:0065007,GO:0065008,GO:0070013,GO:0070161,GO:0070603,GO:0070727,GO:0071840,GO:0071944,GO:0097346,GO:0097433,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:1902494,GO:1903047,GO:1904949 - 2.181e-250 772.0
HKD2_k127_2554686_0 type I restriction modification DNA specificity domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 332.0
HKD2_k127_2554686_1 PFAM Cytochrome C K04561 - 1.7.2.5 0.000000000000003925 78.0
HKD2_k127_2554686_2 Homeodomain-like domain - - - 0.0000005859 51.0
HKD2_k127_2554691_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 533.0
HKD2_k127_2554691_1 Protein of unknown function (DUF1778) - - - 0.0000000000000000000001447 99.0
HKD2_k127_2554691_2 ISXO2-like transposase domain - - - 0.0000000000000001641 79.0
HKD2_k127_2559788_0 Sulfatase - - - 2.128e-288 899.0
HKD2_k127_2559788_1 MlaD protein K06192 - - 1.93e-254 795.0
HKD2_k127_2559788_10 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007426 241.0
HKD2_k127_2559788_11 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000000000000000000000000001392 206.0
HKD2_k127_2559788_12 Phosphopantetheine attachment site - - - 0.00000000000000000008021 96.0
HKD2_k127_2559788_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 525.0
HKD2_k127_2559788_3 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 483.0
HKD2_k127_2559788_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 478.0
HKD2_k127_2559788_5 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 457.0
HKD2_k127_2559788_6 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 371.0
HKD2_k127_2559788_7 PFAM Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 283.0
HKD2_k127_2559788_8 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001657 282.0
HKD2_k127_2559788_9 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000004223 246.0
HKD2_k127_2564416_0 PFAM outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 468.0
HKD2_k127_2564416_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 353.0
HKD2_k127_2564416_2 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006526 255.0
HKD2_k127_2564416_3 beta-lactamase - - - 0.000000000000000000000000000000000000000003459 180.0
HKD2_k127_2583167_0 Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 364.0
HKD2_k127_2583167_1 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 288.0
HKD2_k127_2583167_2 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001684 239.0
HKD2_k127_2583167_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000009253 226.0
HKD2_k127_2583167_4 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000002145 225.0
HKD2_k127_2588736_0 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.0 1222.0
HKD2_k127_2588736_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.872e-263 827.0
HKD2_k127_2588736_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 2.095e-242 752.0
HKD2_k127_2588736_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 323.0
HKD2_k127_2588736_4 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 305.0
HKD2_k127_2588736_6 SpoVT / AbrB like domain - - - 0.0000000000001565 72.0
HKD2_k127_2602094_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 530.0
HKD2_k127_2602094_1 Chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001215 275.0
HKD2_k127_2602094_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000007031 233.0
HKD2_k127_2602094_3 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000000000000000000001606 187.0
HKD2_k127_2602094_4 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000008333 144.0
HKD2_k127_2602094_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000001047 105.0
HKD2_k127_2602094_6 Protein of unknown function (DUF1566) - - - 0.00000000000000000000007825 106.0
HKD2_k127_2602094_7 - K07138 - - 0.00000000000000004746 84.0
HKD2_k127_2611471_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1194.0
HKD2_k127_2611471_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 302.0
HKD2_k127_2613392_0 histidine kinase HAMP region domain protein - - - 0.0 1256.0
HKD2_k127_2613392_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 472.0
HKD2_k127_2616689_0 - K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 490.0
HKD2_k127_2616689_1 Nacht domain - - - 0.0000000001006 68.0
HKD2_k127_2616689_2 - - - - 0.00000001654 61.0
HKD2_k127_2619577_0 histidine kinase HAMP region domain protein K03406 - - 0.0 1538.0
HKD2_k127_2623810_0 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 405.0
HKD2_k127_2623810_1 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 323.0
HKD2_k127_2623810_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000001258 238.0
HKD2_k127_2623810_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000000000000000000000000001505 211.0
HKD2_k127_2623810_4 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000001169 159.0
HKD2_k127_2623810_5 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000004898 111.0
HKD2_k127_2623810_6 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000001274 60.0
HKD2_k127_2623810_7 Phosphoribosyl transferase domain K07100 - - 0.00002798 48.0
HKD2_k127_2629204_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 1.477e-260 805.0
HKD2_k127_2629204_1 Major Facilitator Superfamily K02429 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 503.0
HKD2_k127_2629204_2 WLM domain K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001025 263.0
HKD2_k127_2629204_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000002379 243.0
HKD2_k127_2629204_4 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000001738 130.0
HKD2_k127_2629204_5 nUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000002566 67.0
HKD2_k127_2648308_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.442e-284 879.0
HKD2_k127_2648308_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 9.455e-196 613.0
HKD2_k127_2648308_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 285.0
HKD2_k127_2659080_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 595.0
HKD2_k127_2659919_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 388.0
HKD2_k127_2659919_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 333.0
HKD2_k127_2659919_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 336.0
HKD2_k127_2659919_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001872 192.0
HKD2_k127_2659919_4 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000000000000000000000000000000000000007455 162.0
HKD2_k127_2659919_5 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000009386 89.0
HKD2_k127_2659919_6 PFAM Glycosyl transferases group 1 - - - 0.000000000005706 67.0
HKD2_k127_2672728_0 Isocitrate dehydrogenase NADP-dependent, monomeric type K00031 - 1.1.1.42 0.0 1312.0
HKD2_k127_2672728_1 cluster binding protein - - - 0.0 1239.0
HKD2_k127_2672728_10 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 1.434e-240 747.0
HKD2_k127_2672728_11 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 3.035e-235 737.0
HKD2_k127_2672728_12 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 5.696e-222 693.0
HKD2_k127_2672728_13 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.295e-221 689.0
HKD2_k127_2672728_14 Type VI secretion system, TssF K11896 - - 3.236e-218 693.0
HKD2_k127_2672728_15 Phage late control gene D protein (GPD) K11904 - - 1.467e-209 668.0
HKD2_k127_2672728_16 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 595.0
HKD2_k127_2672728_17 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 585.0
HKD2_k127_2672728_18 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 563.0
HKD2_k127_2672728_19 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 538.0
HKD2_k127_2672728_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0 1191.0
HKD2_k127_2672728_20 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 498.0
HKD2_k127_2672728_21 Regulatory protein GntR HTH K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 426.0
HKD2_k127_2672728_22 Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 349.0
HKD2_k127_2672728_23 ImpA, N-terminal, type VI secretion system K11902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 342.0
HKD2_k127_2672728_24 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 318.0
HKD2_k127_2672728_25 type VI secretion protein K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007712 291.0
HKD2_k127_2672728_26 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006384 266.0
HKD2_k127_2672728_27 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009828 255.0
HKD2_k127_2672728_28 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008272 246.0
HKD2_k127_2672728_29 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002202 243.0
HKD2_k127_2672728_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1137.0
HKD2_k127_2672728_30 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000005279 238.0
HKD2_k127_2672728_31 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000000000000000001502 224.0
HKD2_k127_2672728_32 Type VI secretion system protein DotU K11892 - - 0.00000000000000000000000000000000000000000000000000000000001643 213.0
HKD2_k127_2672728_33 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000007835 209.0
HKD2_k127_2672728_34 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000001512 176.0
HKD2_k127_2672728_35 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000000000000000007736 136.0
HKD2_k127_2672728_36 Type VI secretion - - - 0.00000000000000000000000000000001439 138.0
HKD2_k127_2672728_37 Gene 25-like lysozyme K11897 - - 0.00000000000000000000000000000002262 132.0
HKD2_k127_2672728_39 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000002104 50.0
HKD2_k127_2672728_4 TIGRFAM L-lactate transport K03303 - - 0.0 1084.0
HKD2_k127_2672728_5 ImcF-related N-terminal domain K11891 - - 0.0 1066.0
HKD2_k127_2672728_6 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 9.559e-292 908.0
HKD2_k127_2672728_7 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 3.824e-268 828.0
HKD2_k127_2672728_8 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 2.211e-256 799.0
HKD2_k127_2672728_9 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 2.021e-252 780.0
HKD2_k127_2674693_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12137 - - 4.487e-297 923.0
HKD2_k127_2674693_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 4.973e-291 906.0
HKD2_k127_2674693_10 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 458.0
HKD2_k127_2674693_11 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 432.0
HKD2_k127_2674693_12 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 438.0
HKD2_k127_2674693_13 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 390.0
HKD2_k127_2674693_14 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 360.0
HKD2_k127_2674693_15 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 353.0
HKD2_k127_2674693_16 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 342.0
HKD2_k127_2674693_17 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 322.0
HKD2_k127_2674693_18 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 279.0
HKD2_k127_2674693_2 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 2.692e-285 882.0
HKD2_k127_2674693_3 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 1.456e-254 790.0
HKD2_k127_2674693_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 3.588e-254 791.0
HKD2_k127_2674693_5 Polysulphide reductase, NrfD - - - 3.909e-227 714.0
HKD2_k127_2674693_6 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 538.0
HKD2_k127_2674693_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 524.0
HKD2_k127_2674693_8 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 518.0
HKD2_k127_2674693_9 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 499.0
HKD2_k127_2675506_0 General secretory system II, protein E domain protein K02652 - - 0.0 1037.0
HKD2_k127_2675506_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.873e-282 885.0
HKD2_k127_2675506_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 461.0
HKD2_k127_2675506_11 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 459.0
HKD2_k127_2675506_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 398.0
HKD2_k127_2675506_13 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.0000000000000000000000003871 105.0
HKD2_k127_2675506_2 Protein of unknown function (DUF2723) - - - 3.735e-277 880.0
HKD2_k127_2675506_3 PFAM Lytic transglycosylase catalytic K08309 - - 1.955e-276 870.0
HKD2_k127_2675506_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 2.149e-252 785.0
HKD2_k127_2675506_5 Sensor histidine kinase PilS, PAS domain-containing K02668,K07709 - 2.7.13.3 9.93e-230 723.0
HKD2_k127_2675506_6 PFAM type II secretion system K02653 - - 3.849e-224 699.0
HKD2_k127_2675506_7 twitching motility protein K02669 - - 8.503e-221 687.0
HKD2_k127_2675506_8 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 518.0
HKD2_k127_2675506_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 479.0
HKD2_k127_2686894_0 Transposase, Mutator family K07493 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 595.0
HKD2_k127_2686894_1 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000000000000004807 120.0
HKD2_k127_2687701_0 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001719 228.0
HKD2_k127_2694685_0 Cytochrome c554 and c-prime - - - 5.85e-220 687.0
HKD2_k127_2694685_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 289.0
HKD2_k127_2696565_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1137.0
HKD2_k127_2696565_1 PFAM ABC transporter related K06020 - 3.6.3.25 0.0 1046.0
HKD2_k127_2696565_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 436.0
HKD2_k127_2696565_11 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 411.0
HKD2_k127_2696565_12 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 417.0
HKD2_k127_2696565_13 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 413.0
HKD2_k127_2696565_14 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 344.0
HKD2_k127_2696565_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004161 274.0
HKD2_k127_2696565_16 unfolded protein binding K06142 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002323 268.0
HKD2_k127_2696565_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000001061 247.0
HKD2_k127_2696565_18 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
HKD2_k127_2696565_19 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000001181 217.0
HKD2_k127_2696565_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 1.399e-314 970.0
HKD2_k127_2696565_20 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000357 200.0
HKD2_k127_2696565_21 Lipopolysaccharide kinase (Kdo/WaaP) family K11211 - 2.7.1.166 0.0000000000000000000000000000000000000001383 160.0
HKD2_k127_2696565_23 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000005136 143.0
HKD2_k127_2696565_24 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.0000000000000000000000001495 106.0
HKD2_k127_2696565_25 Trm112p-like protein K09791 - - 0.0000000000002633 73.0
HKD2_k127_2696565_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.062e-304 935.0
HKD2_k127_2696565_4 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 2.865e-232 722.0
HKD2_k127_2696565_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 595.0
HKD2_k127_2696565_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 571.0
HKD2_k127_2696565_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 533.0
HKD2_k127_2696565_8 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 510.0
HKD2_k127_2696565_9 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 453.0
HKD2_k127_2701837_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000001764 205.0
HKD2_k127_2701837_1 Anabaena sensory rhodopsin transducer - - - 0.00000000000000000000000000000000000000000000002514 171.0
HKD2_k127_2701837_2 von Willebrand factor, type A - - - 0.0000000000000000000000000002217 119.0
HKD2_k127_2704352_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 580.0
HKD2_k127_2704352_1 Histidine kinase K20971,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 375.0
HKD2_k127_2704352_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 344.0
HKD2_k127_2704352_3 response regulator K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 305.0
HKD2_k127_2704352_4 HAD-superfamily hydrolase, subfamily IA, variant 2 (HAD-like) K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008409 256.0
HKD2_k127_2704352_5 cheY-homologous receiver domain - - - 0.0000000000000000000000004953 108.0
HKD2_k127_2766363_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 8.913e-268 827.0
HKD2_k127_2766363_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 592.0
HKD2_k127_2766363_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 376.0
HKD2_k127_2766363_3 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.00000000000000000000000000000000006184 134.0
HKD2_k127_2771330_0 DNA invertase Pin K06400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 543.0
HKD2_k127_2771330_1 Type II intron maturase - - - 0.000000000000000000000000000000000252 139.0
HKD2_k127_2785836_0 PFAM Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007752 285.0
HKD2_k127_2792347_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0 1071.0
HKD2_k127_2792347_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 321.0
HKD2_k127_2792347_3 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000003507 56.0
HKD2_k127_2794517_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 6.987e-319 1031.0
HKD2_k127_2794517_1 Berberine and berberine like - - - 5.603e-254 788.0
HKD2_k127_2794517_10 - - - - 0.000000000000000000000000000000000000000000000000000006359 201.0
HKD2_k127_2794517_2 Domain of unknown function (DUF4445) - - - 9.078e-228 722.0
HKD2_k127_2794517_3 Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 6.286e-225 706.0
HKD2_k127_2794517_4 SMART Elongator protein 3 MiaB NifB - - - 1.261e-210 661.0
HKD2_k127_2794517_5 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 451.0
HKD2_k127_2794517_6 Methionine synthase B12-binding module cap domain protein K00548,K14081,K16179 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 378.0
HKD2_k127_2794517_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 314.0
HKD2_k127_2794517_8 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003883 286.0
HKD2_k127_2794517_9 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000000000000000003777 235.0
HKD2_k127_2799359_0 PFAM Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 405.0
HKD2_k127_2799359_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 300.0
HKD2_k127_2799359_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
HKD2_k127_2799359_3 - - - - 0.0000000000000000000007516 96.0
HKD2_k127_2799359_4 - - - - 0.00000000000000000001428 95.0
HKD2_k127_2803123_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002556 283.0
HKD2_k127_2803123_2 regulation of cell shape K04074,K07484 - - 0.000000003992 66.0
HKD2_k127_2803123_3 - - - - 0.0002451 48.0
HKD2_k127_282870_0 PFAM General secretory system II protein E domain protein - - - 9.534e-249 779.0
HKD2_k127_282870_1 Type II/IV secretion system protein K02669 - - 1.014e-198 622.0
HKD2_k127_282870_2 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 578.0
HKD2_k127_282870_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 552.0
HKD2_k127_282870_4 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 542.0
HKD2_k127_282870_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 514.0
HKD2_k127_282870_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 464.0
HKD2_k127_284910_0 - - - - 0.00000000000000000000000007187 112.0
HKD2_k127_284910_2 - - - - 0.0000000000003766 71.0
HKD2_k127_284910_4 ORF located using Blastx - - - 0.000000000007391 72.0
HKD2_k127_2876067_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.6e-273 842.0
HKD2_k127_2876067_1 Histidine kinase K02482 - 2.7.13.3 6.619e-271 871.0
HKD2_k127_2876067_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 355.0
HKD2_k127_2876067_11 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 317.0
HKD2_k127_2876067_12 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001016 267.0
HKD2_k127_2876067_13 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
HKD2_k127_2876067_14 Glyoxalase-like domain K01759,K08234 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000003669 222.0
HKD2_k127_2876067_15 PFAM NosL family protein - - - 0.0000000000000000000000000000000000000000000000000000000009648 205.0
HKD2_k127_2876067_16 - - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
HKD2_k127_2876067_17 NosL - - - 0.000000000000000000000000000000000000000000000000000004547 197.0
HKD2_k127_2876067_18 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000004581 191.0
HKD2_k127_2876067_19 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.00000000000000000000000000000000000000001492 155.0
HKD2_k127_2876067_2 PFAM Major Facilitator Superfamily - - - 7.424e-212 665.0
HKD2_k127_2876067_20 cell redox homeostasis - - - 0.0000000000000000000000000000000000000003467 157.0
HKD2_k127_2876067_21 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000179 117.0
HKD2_k127_2876067_22 membrane - - - 0.0000000000000000000000000003637 117.0
HKD2_k127_2876067_23 - - - - 0.0000000000000000000000002071 108.0
HKD2_k127_2876067_24 Rubredoxin - - - 0.0000000000000000000000007398 104.0
HKD2_k127_2876067_25 - - - - 0.00000000000000000001018 96.0
HKD2_k127_2876067_26 organic phosphonate transport K02044 - - 0.00000000000000003682 89.0
HKD2_k127_2876067_27 LacY proton/sugar symporter - - - 0.0002896 45.0
HKD2_k127_2876067_3 PFAM Extracellular ligand-binding receptor K01999 - - 1.003e-211 661.0
HKD2_k127_2876067_4 PFAM Extracellular ligand-binding receptor K01999 - - 1.188e-208 654.0
HKD2_k127_2876067_5 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 528.0
HKD2_k127_2876067_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 511.0
HKD2_k127_2876067_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 497.0
HKD2_k127_2876067_8 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 444.0
HKD2_k127_2876067_9 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 345.0
HKD2_k127_2886752_0 - - - - 0.00000000000001313 85.0
HKD2_k127_2886752_1 polygalacturonase activity - - - 0.000000009495 68.0
HKD2_k127_2931977_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.396e-314 969.0
HKD2_k127_2931977_1 PFAM NDP-hexose 23-dehydratase K16435 - 4.2.1.159 1.305e-202 641.0
HKD2_k127_2931977_10 Hsp20/alpha crystallin family K13993 - - 0.000000004566 59.0
HKD2_k127_2931977_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 607.0
HKD2_k127_2931977_3 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 618.0
HKD2_k127_2931977_4 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 433.0
HKD2_k127_2931977_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 359.0
HKD2_k127_2931977_6 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 331.0
HKD2_k127_2931977_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 261.0
HKD2_k127_2931977_8 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000008409 217.0
HKD2_k127_2931977_9 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000000000000000004104 202.0
HKD2_k127_2947235_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 509.0
HKD2_k127_2947235_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 500.0
HKD2_k127_2947235_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 411.0
HKD2_k127_2953465_0 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000005354 102.0
HKD2_k127_2975038_0 TIGRFAM conserved repeat domain - - - 0.0 1694.0
HKD2_k127_2975038_1 Histidine kinase - - - 0.0 1026.0
HKD2_k127_2975038_2 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006125 253.0
HKD2_k127_2975038_3 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000001439 162.0
HKD2_k127_2975038_5 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000007936 145.0
HKD2_k127_3010614_0 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 5.254e-299 921.0
HKD2_k127_3010614_1 Domain of unknown function (DUF4445) - - - 2.909e-246 771.0
HKD2_k127_3010614_10 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 341.0
HKD2_k127_3010614_11 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 323.0
HKD2_k127_3010614_12 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 312.0
HKD2_k127_3010614_13 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 308.0
HKD2_k127_3010614_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 294.0
HKD2_k127_3010614_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000014 295.0
HKD2_k127_3010614_16 Domain of unknown function (DUF4384) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 291.0
HKD2_k127_3010614_17 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009043 299.0
HKD2_k127_3010614_18 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005422 257.0
HKD2_k127_3010614_19 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000001139 266.0
HKD2_k127_3010614_2 COG2710 Nitrogenase molybdenum-iron protein alpha and beta K02591 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 581.0
HKD2_k127_3010614_20 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000007973 211.0
HKD2_k127_3010614_21 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000001573 135.0
HKD2_k127_3010614_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 564.0
HKD2_k127_3010614_4 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 539.0
HKD2_k127_3010614_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 532.0
HKD2_k127_3010614_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 529.0
HKD2_k127_3010614_7 -ABC-type branched-chain amino acid transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 466.0
HKD2_k127_3010614_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 393.0
HKD2_k127_3010614_9 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 382.0
HKD2_k127_3016542_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 1.592e-287 887.0
HKD2_k127_3016542_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001758 277.0
HKD2_k127_3016542_2 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001372 243.0
HKD2_k127_3016542_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009146 246.0
HKD2_k127_3032756_0 Transglycosylase SLT domain - - - 0.0000002798 64.0
HKD2_k127_304864_0 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 471.0
HKD2_k127_304864_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 391.0
HKD2_k127_304864_2 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 366.0
HKD2_k127_304864_3 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 330.0
HKD2_k127_304864_4 Pfam:TPM K08988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008931 274.0
HKD2_k127_3053578_0 PFAM alpha amylase catalytic region - - - 0.0 1725.0
HKD2_k127_3053578_1 histidine kinase HAMP region domain protein K03406 - - 0.0 1209.0
HKD2_k127_3053578_2 TIGRFAM YidE YbjL duplication K07085 - - 7.223e-298 925.0
HKD2_k127_3053578_3 phosphorelay signal transduction system - - - 5.167e-257 809.0
HKD2_k127_3053578_4 PFAM peptidase M16 domain protein - - - 4.752e-218 688.0
HKD2_k127_3053578_5 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 576.0
HKD2_k127_3053578_6 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 461.0
HKD2_k127_3053578_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 446.0
HKD2_k127_3053578_8 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000006971 134.0
HKD2_k127_3059304_0 PAS domain containing protein K07315,K07675 - 2.7.13.3,3.1.3.3 0.0 1348.0
HKD2_k127_3059304_1 TIGRFAM cytochrome C family protein - - - 6.621e-260 849.0
HKD2_k127_3059304_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 384.0
HKD2_k127_3059304_12 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
HKD2_k127_3059304_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008509 266.0
HKD2_k127_3059304_14 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.000000000000000000000000000000000000000000000000000000000000002031 239.0
HKD2_k127_3059304_15 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000006087 192.0
HKD2_k127_3059304_18 Pro-kumamolisin, activation domain K08677 - - 0.000000000000000000000000000000000000000005315 179.0
HKD2_k127_3059304_19 - - - - 0.0000000000000000000000000000000000000000132 156.0
HKD2_k127_3059304_2 response regulator - - - 2.003e-250 781.0
HKD2_k127_3059304_20 - - - - 0.0000000000000000000000000000009154 124.0
HKD2_k127_3059304_21 - - - - 0.0000000000000000000004222 96.0
HKD2_k127_3059304_22 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000255 79.0
HKD2_k127_3059304_24 - - - - 0.0000000098 58.0
HKD2_k127_3059304_27 small metal-binding protein - - - 0.00002354 48.0
HKD2_k127_3059304_28 Histidine kinase-like ATPases K04079 - - 0.0001412 55.0
HKD2_k127_3059304_3 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 1.135e-215 669.0
HKD2_k127_3059304_4 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006572 519.0
HKD2_k127_3059304_5 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 471.0
HKD2_k127_3059304_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 451.0
HKD2_k127_3059304_7 Transposase K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 448.0
HKD2_k127_3059304_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 417.0
HKD2_k127_3059304_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 441.0
HKD2_k127_3086057_0 ATP-binding region, ATPase domain protein - - - 0.0 1682.0
HKD2_k127_3086057_1 ATP-binding region, ATPase domain protein - - - 0.0 1642.0
HKD2_k127_3086057_10 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000001115 229.0
HKD2_k127_3086057_11 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000004682 244.0
HKD2_k127_3086057_12 metal-dependent phosphohydrolase HD region K07814 - - 0.000000000000000000000000000000000000000006103 159.0
HKD2_k127_3086057_2 Histidine kinase A domain protein - - - 0.0 1057.0
HKD2_k127_3086057_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0 1006.0
HKD2_k127_3086057_4 PFAM Major facilitator superfamily K08224 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 571.0
HKD2_k127_3086057_5 protein histidine kinase activity K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 580.0
HKD2_k127_3086057_6 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 482.0
HKD2_k127_3086057_7 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 338.0
HKD2_k127_3086057_8 methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
HKD2_k127_3086057_9 protein histidine kinase activity K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009985 291.0
HKD2_k127_309045_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 1.015e-222 694.0
HKD2_k127_309045_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 369.0
HKD2_k127_309045_2 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000006697 115.0
HKD2_k127_310522_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 9.464e-226 708.0
HKD2_k127_310522_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 1.444e-209 668.0
HKD2_k127_310522_2 COG1960 Acyl-CoA dehydrogenases K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 583.0
HKD2_k127_310522_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 466.0
HKD2_k127_310522_4 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 377.0
HKD2_k127_310522_5 3-hydroxyacyl-CoA dehydrogenase NAD-binding K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000001184 270.0
HKD2_k127_310522_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000161 267.0
HKD2_k127_310522_7 Short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000002028 101.0
HKD2_k127_3110422_0 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 322.0
HKD2_k127_3110422_1 phosphoenolpyruvate-protein phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005854 269.0
HKD2_k127_3110422_2 - - - - 0.00000000000000000000000000000000000001491 154.0
HKD2_k127_3110422_3 ThiS family - - - 0.0000000000000009668 79.0
HKD2_k127_3137772_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000007197 224.0
HKD2_k127_3137772_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000006708 126.0
HKD2_k127_3142903_0 Conserved carboxylase domain K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 0.0 1165.0
HKD2_k127_3142903_1 PFAM carboxyl transferase K01615 - 4.1.1.70 0.0 1121.0
HKD2_k127_3142903_2 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 1.294e-235 731.0
HKD2_k127_3142903_3 Short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000002028 101.0
HKD2_k127_3142903_4 malic protein domain protein K00029 - 1.1.1.40 0.00000000000000002815 83.0
HKD2_k127_3153430_0 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004 285.0
HKD2_k127_3153430_1 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000009238 175.0
HKD2_k127_3153430_2 Polymorphic membrane protein, Chlamydia - - - 0.000000000000000000000000000006291 139.0
HKD2_k127_3166314_0 Transposase IS4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 300.0
HKD2_k127_3173104_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 421.0
HKD2_k127_3178813_0 Phage tail tube protein - - - 0.0000000000000000000000000005915 117.0
HKD2_k127_3194986_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1097.0
HKD2_k127_3194986_1 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 1.291e-236 746.0
HKD2_k127_3194986_10 - - - - 0.00000000000000000000000000001202 118.0
HKD2_k127_3194986_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 1.941e-227 729.0
HKD2_k127_3194986_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 2.285e-201 633.0
HKD2_k127_3194986_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 500.0
HKD2_k127_3194986_5 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 397.0
HKD2_k127_3194986_6 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004593 276.0
HKD2_k127_3194986_7 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000003403 233.0
HKD2_k127_3194986_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000001212 179.0
HKD2_k127_3194986_9 STAS domain - - - 0.000000000000000000000000000000000000004656 148.0
HKD2_k127_3209016_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 5.034e-229 717.0
HKD2_k127_3209016_1 Putative diguanylate phosphodiesterase - - - 4.426e-221 700.0
HKD2_k127_3209016_10 Domain of Unknown Function (DUF1540) - - - 0.0000000000000000000000000000000000000000000000000000006247 193.0
HKD2_k127_3209016_11 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000001042 183.0
HKD2_k127_3209016_12 regulatory protein, arsR K03892,K21903 - - 0.00000000000000000000000000000000000000000000558 165.0
HKD2_k127_3209016_13 electron transfer activity K05337 - - 0.00000000000000000000000000155 115.0
HKD2_k127_3209016_15 fibronectin type III domain protein - - - 0.0000002439 53.0
HKD2_k127_3209016_2 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 613.0
HKD2_k127_3209016_3 Histidine kinase K07709 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010288,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071241,GO:0071248,GO:0071284,GO:0071294,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 503.0
HKD2_k127_3209016_4 PFAM flagellin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 445.0
HKD2_k127_3209016_5 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 443.0
HKD2_k127_3209016_6 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 319.0
HKD2_k127_3209016_7 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 318.0
HKD2_k127_3209016_8 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000001335 207.0
HKD2_k127_3209016_9 two component, sigma54 specific, transcriptional regulator, Fis family K10943 - - 0.0000000000000000000000000000000000000000000000000000000001696 205.0
HKD2_k127_3230509_0 Amidohydrolase family - - - 8e-323 995.0
HKD2_k127_3230509_1 Belongs to the heat shock protein 70 family K04046 - - 5.899e-231 719.0
HKD2_k127_3230509_2 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 501.0
HKD2_k127_3230509_3 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 436.0
HKD2_k127_3230509_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 463.0
HKD2_k127_3230509_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 408.0
HKD2_k127_3230509_6 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 400.0
HKD2_k127_3230509_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 354.0
HKD2_k127_3230509_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 333.0
HKD2_k127_3230509_9 Antibiotic biosynthesis monooxygenase K09932 - - 0.00000000000000000000000000000000000000000007115 166.0
HKD2_k127_3248958_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 595.0
HKD2_k127_3248958_1 Helix-turn-helix domain of transposase family ISL3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 528.0
HKD2_k127_3248958_2 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 333.0
HKD2_k127_3248958_3 Winged helix-turn helix - - - 0.000000000000000000006018 102.0
HKD2_k127_3315488_0 Catalase K03781 - 1.11.1.6 9.337e-279 865.0
HKD2_k127_3315488_1 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 1.912e-213 671.0
HKD2_k127_3315488_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 607.0
HKD2_k127_3315488_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 600.0
HKD2_k127_3315488_4 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 421.0
HKD2_k127_3315488_5 Belongs to the 5'-nucleotidase family - - - 0.0000000000000000000000000000000000000000000000000000000001641 219.0
HKD2_k127_3315488_6 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000001684 168.0
HKD2_k127_338789_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204 1.9.3.1 0.00000000000000000000000000000000000000000000136 165.0
HKD2_k127_338789_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204 1.9.3.1 0.000000000000000000000001395 103.0
HKD2_k127_338789_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204 1.9.3.1 0.00000000000000000000009663 97.0
HKD2_k127_338789_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204 1.9.3.1 0.0000000000000000000002504 96.0
HKD2_k127_338789_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204 1.9.3.1 0.0000000000000000000295 90.0
HKD2_k127_338789_5 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204 1.9.3.1 0.000000000000000003656 83.0
HKD2_k127_338789_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02256 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005751,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006979,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007568,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009628,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0017144,GO:0019637,GO:0019646,GO:0019693,GO:0019866,GO:0021549,GO:0022037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0030902,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032991,GO:0034220,GO:0034641,GO:0042221,GO:0042773,GO:0042775,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045275,GO:0045277,GO:0045333,GO:0046034,GO:0046483,GO:0046686,GO:0046688,GO:0048513,GO:0048731,GO:0048856,GO:0050896,GO:0051179,GO:0051234,GO:0051597,GO:0051602,GO:0055085,GO:0055086,GO:0055114,GO:0060322,GO:0070069,GO:0070469,GO:0071704,GO:0072521,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1902600,GO:1990204 1.9.3.1 0.0000000000000006563 77.0
HKD2_k127_3441262_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 550.0
HKD2_k127_3441262_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 362.0
HKD2_k127_3441262_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008714 230.0
HKD2_k127_3511011_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 363.0
HKD2_k127_352733_0 Rhodopirellula transposase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 429.0
HKD2_k127_352733_2 transposition K07497 - - 0.000000000000001953 83.0
HKD2_k127_354492_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003207 262.0
HKD2_k127_354492_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0005068 49.0
HKD2_k127_355728_0 NHL repeat - - - 1.323e-214 709.0
HKD2_k127_355728_1 MacB-like periplasmic core domain K02004 - - 8.731e-211 659.0
HKD2_k127_355728_2 MacB-like periplasmic core domain K02004 - - 1.763e-208 652.0
HKD2_k127_355728_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 543.0
HKD2_k127_355728_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 393.0
HKD2_k127_355728_5 S-layer homology domain - - - 0.00000000000000000000000000000000000000001102 178.0
HKD2_k127_355728_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K20276 - - 0.000000000000000000000000000000006794 142.0
HKD2_k127_355728_7 Protein conserved in bacteria K09764 - - 0.00000000000000000000000000000007745 126.0
HKD2_k127_355728_8 domain, Protein - - - 0.000000000000000001525 98.0
HKD2_k127_3559634_0 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 337.0
HKD2_k127_3559634_1 COG4644 Transposase and inactivated derivatives TnpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002294 243.0
HKD2_k127_3559634_2 Transposase - - - 0.000000000000000000255 90.0
HKD2_k127_3567056_0 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 380.0
HKD2_k127_3567056_1 NUBPL iron-transfer P-loop NTPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003296 246.0
HKD2_k127_3567056_2 S23 ribosomal protein - - - 0.000000000000000000000000000000003534 132.0
HKD2_k127_3597_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1046.0
HKD2_k127_3597_1 4Fe-4S dicluster domain - - - 2.558e-307 953.0
HKD2_k127_3597_10 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000002307 143.0
HKD2_k127_3597_11 nuclear chromosome segregation - - - 0.00000000000000000000000000001314 130.0
HKD2_k127_3597_12 Chitinase class I K03791 - - 0.000000003655 66.0
HKD2_k127_3597_13 fibronectin type III domain protein - - - 0.0001124 46.0
HKD2_k127_3597_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 6.321e-233 726.0
HKD2_k127_3597_3 electron transfer flavoprotein, alpha subunit K03522 - - 5.038e-228 712.0
HKD2_k127_3597_4 Belongs to the thiolase family K00626 - 2.3.1.9 6.21e-219 690.0
HKD2_k127_3597_5 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 498.0
HKD2_k127_3597_6 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 435.0
HKD2_k127_3597_7 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 431.0
HKD2_k127_3597_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 346.0
HKD2_k127_3597_9 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000000002123 197.0
HKD2_k127_363629_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1560.0
HKD2_k127_363629_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1456.0
HKD2_k127_363629_2 Histidine kinase - - - 1e-279 884.0
HKD2_k127_363629_3 histidine kinase, dimerisation and phosphoacceptor region - - - 8.464e-217 680.0
HKD2_k127_363629_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 505.0
HKD2_k127_363629_5 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 381.0
HKD2_k127_363629_6 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001234 282.0
HKD2_k127_363629_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000009813 180.0
HKD2_k127_363629_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000001019 171.0
HKD2_k127_363629_9 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000005322 141.0
HKD2_k127_365109_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 462.0
HKD2_k127_365109_1 PFAM Transposase - - - 0.000000000000005914 78.0
HKD2_k127_3766060_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 334.0
HKD2_k127_3766060_1 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000001267 199.0
HKD2_k127_3766060_2 PFAM Transposase DDE domain - - - 0.0000000000004266 70.0
HKD2_k127_3766060_3 Mechanosensitive ion channel - - - 0.000003829 57.0
HKD2_k127_3766060_4 Protein of unknown function (DUF1298) - - - 0.00001261 49.0
HKD2_k127_3836883_0 Psort location CytoplasmicMembrane, score - - - 1.326e-285 893.0
HKD2_k127_3836883_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 428.0
HKD2_k127_3836883_2 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 372.0
HKD2_k127_3836883_3 Protein of unknown function (DUF721) - - - 0.000000000000000000000000000000000000000000000000000000000000006917 220.0
HKD2_k127_3836883_4 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000002953 144.0
HKD2_k127_3836883_5 - - - - 0.0000000000000000000000000000002381 124.0
HKD2_k127_3847057_0 Belongs to the thiolase family K00626 - 2.3.1.9 1.086e-307 948.0
HKD2_k127_3847057_1 PFAM aminotransferase, class I and II K00814 - 2.6.1.2 2.569e-260 805.0
HKD2_k127_3847057_10 chemotaxis K03408,K03415 - - 0.000000000000000000000000000000001757 136.0
HKD2_k127_3847057_2 transmembrane signaling receptor activity K03406 - - 2.14e-204 643.0
HKD2_k127_3847057_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 411.0
HKD2_k127_3847057_4 Chemotaxis K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 379.0
HKD2_k127_3847057_5 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000009585 195.0
HKD2_k127_3847057_6 - - - - 0.000000000000000000000000000000000000000000000000000007945 195.0
HKD2_k127_3847057_7 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000007972 192.0
HKD2_k127_3847057_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000001343 188.0
HKD2_k127_3847057_9 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000001431 169.0
HKD2_k127_3874034_0 Metal-dependent phosphohydrolase K07037 - - 0.0 1262.0
HKD2_k127_3874034_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1045.0
HKD2_k127_3874034_10 Protein of unknown function (DUF1015) - - - 2.9e-233 725.0
HKD2_k127_3874034_11 Protein of unknown function (DUF512) - - - 1.226e-226 707.0
HKD2_k127_3874034_12 PFAM RNA binding S1 domain protein K02945 - - 2.11e-212 664.0
HKD2_k127_3874034_13 dioxygenase K00464 - 1.13.11.75 8.358e-211 666.0
HKD2_k127_3874034_14 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 5.699e-205 640.0
HKD2_k127_3874034_15 belongs to the CobB CobQ family K06873 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 597.0
HKD2_k127_3874034_16 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 477.0
HKD2_k127_3874034_17 S4 RNA-binding domain K06175 - 5.4.99.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 468.0
HKD2_k127_3874034_18 PFAM CBS domain containing protein K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 476.0
HKD2_k127_3874034_19 PFAM import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 444.0
HKD2_k127_3874034_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.66e-304 948.0
HKD2_k127_3874034_20 PFAM NLP P60 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 435.0
HKD2_k127_3874034_21 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 454.0
HKD2_k127_3874034_22 CRISPR-associated endoribonuclease Cas6 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 398.0
HKD2_k127_3874034_24 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 356.0
HKD2_k127_3874034_25 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 347.0
HKD2_k127_3874034_26 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 349.0
HKD2_k127_3874034_27 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 341.0
HKD2_k127_3874034_28 Metal-dependent phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 335.0
HKD2_k127_3874034_29 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 318.0
HKD2_k127_3874034_3 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 1.084e-299 923.0
HKD2_k127_3874034_30 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000056 261.0
HKD2_k127_3874034_31 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008676 254.0
HKD2_k127_3874034_32 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003619 248.0
HKD2_k127_3874034_33 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000134 247.0
HKD2_k127_3874034_34 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000001799 235.0
HKD2_k127_3874034_35 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000000000000000000000002268 202.0
HKD2_k127_3874034_36 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000008846 153.0
HKD2_k127_3874034_37 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000000000000008634 140.0
HKD2_k127_3874034_38 Protein conserved in bacteria K09954 - - 0.000000000000000000000000000000000138 133.0
HKD2_k127_3874034_39 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000003975 120.0
HKD2_k127_3874034_4 Belongs to the RtcB family K14415 - 6.5.1.3 1.184e-292 900.0
HKD2_k127_3874034_40 PFAM Type IV pilus assembly PilZ - - - 0.000000000000000000000000004251 118.0
HKD2_k127_3874034_5 PFAM Cys Met metabolism K01740 - 2.5.1.49 4.903e-271 837.0
HKD2_k127_3874034_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.166e-264 815.0
HKD2_k127_3874034_7 Response regulator, receiver K13246 - 3.1.4.52 2.991e-263 817.0
HKD2_k127_3874034_8 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 1.11e-256 794.0
HKD2_k127_3874034_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 8.538e-243 759.0
HKD2_k127_388243_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 327.0
HKD2_k127_388243_1 Transposase K07497 - - 0.000000000000000000000000000000000002644 139.0
HKD2_k127_3885553_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 1.696e-208 661.0
HKD2_k127_3885553_1 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005989 248.0
HKD2_k127_3885553_2 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000001563 205.0
HKD2_k127_3885553_3 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000004021 190.0
HKD2_k127_3885553_4 DoxX K15977 - - 0.000000000000000000000000000000000000000000000003706 178.0
HKD2_k127_3885553_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000456 154.0
HKD2_k127_3885553_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K17223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000007261 131.0
HKD2_k127_3885553_7 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000001202 117.0
HKD2_k127_3885553_9 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000578 54.0
HKD2_k127_3885888_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002637 263.0
HKD2_k127_3885888_1 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000002324 234.0
HKD2_k127_3894963_0 DNA polymerase K02347 - - 8.963e-284 883.0
HKD2_k127_3894963_1 PFAM Extracellular solute-binding protein, family 3 - - - 9.472e-229 723.0
HKD2_k127_3894963_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000008746 52.0
HKD2_k127_3894963_2 response regulator - - - 8.483e-213 669.0
HKD2_k127_3894963_3 Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane K11103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 613.0
HKD2_k127_3894963_4 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 532.0
HKD2_k127_3894963_5 Sodium:dicarboxylate symporter family K03309,K11102,K11103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 500.0
HKD2_k127_3894963_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 321.0
HKD2_k127_3894963_7 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 293.0
HKD2_k127_3894963_8 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002486 264.0
HKD2_k127_3895133_0 ISXO2-like transposase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 492.0
HKD2_k127_3895133_1 transposase activity - - - 0.000000000000000002198 85.0
HKD2_k127_3896661_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000201 284.0
HKD2_k127_3896661_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003813 272.0
HKD2_k127_3909434_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.509e-286 898.0
HKD2_k127_3909434_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 293.0
HKD2_k127_3909434_2 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000002629 235.0
HKD2_k127_3939315_0 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 449.0
HKD2_k127_3939315_1 Integrase core domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000009638 51.0
HKD2_k127_3940108_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1015.0
HKD2_k127_3940108_1 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 606.0
HKD2_k127_3940108_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 560.0
HKD2_k127_3940108_3 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 507.0
HKD2_k127_3940108_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 451.0
HKD2_k127_3940108_5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 327.0
HKD2_k127_3940108_6 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000000000000009351 165.0
HKD2_k127_3940108_7 PFAM lipopolysaccharide biosynthesis - - - 0.0000000000000000000000003768 109.0
HKD2_k127_3940108_8 DNA polymerase - - - 0.00000000000000000000008799 107.0
HKD2_k127_3958417_0 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 606.0
HKD2_k127_3958417_1 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
HKD2_k127_3961166_0 Glycogen debranching enzyme - - - 0.0 1090.0
HKD2_k127_3961166_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 2.045e-304 943.0
HKD2_k127_3961166_2 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 544.0
HKD2_k127_3961166_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 532.0
HKD2_k127_3961166_4 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 432.0
HKD2_k127_3961166_5 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 408.0
HKD2_k127_3961166_6 Protein of unknown function (DUF2795) - - - 0.0000000000000000000000005137 107.0
HKD2_k127_3964888_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 1.319e-284 888.0
HKD2_k127_3964888_1 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 599.0
HKD2_k127_3964888_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 335.0
HKD2_k127_3964888_4 Outer membrane protein beta-barrel domain K07275 - - 0.000000000000000000000000000000000000001444 150.0
HKD2_k127_3964888_5 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000001559 129.0
HKD2_k127_3964888_7 Two component signalling adaptor domain K03408 - - 0.00000000000122 69.0
HKD2_k127_3977778_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 648.0
HKD2_k127_3977778_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000009428 100.0
HKD2_k127_4000407_0 domain protein K14194 - - 0.0 1746.0
HKD2_k127_4000407_1 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0 1111.0
HKD2_k127_4000407_10 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001055 290.0
HKD2_k127_4000407_2 SMART Elongator protein 3 MiaB NifB - - - 1.301e-247 769.0
HKD2_k127_4000407_3 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 488.0
HKD2_k127_4000407_4 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 441.0
HKD2_k127_4000407_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 463.0
HKD2_k127_4000407_6 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 426.0
HKD2_k127_4000407_7 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 340.0
HKD2_k127_4000407_8 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 312.0
HKD2_k127_4000407_9 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 326.0
HKD2_k127_4027416_0 COG NOG14552 non supervised orthologous group - - - 0.000000000000000000000000000000002827 131.0
HKD2_k127_4027416_1 ORF located using Blastx - - - 0.00000000007996 66.0
HKD2_k127_4027416_2 ORF located using Blastx - - - 0.0001011 44.0
HKD2_k127_4027416_3 - - - - 0.0005555 44.0
HKD2_k127_4028967_0 histidine kinase HAMP region domain protein K03406 - - 1.142e-300 945.0
HKD2_k127_4028967_1 Protein of unknown function (DUF3373) - - - 6.029e-280 868.0
HKD2_k127_4028967_10 Transposase IS200 like - - - 0.00000000005485 70.0
HKD2_k127_4028967_11 Transposase K07491 - - 0.000000000926 63.0
HKD2_k127_4028967_2 Cytochrome c554 and c-prime - - - 1.771e-260 809.0
HKD2_k127_4028967_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 606.0
HKD2_k127_4028967_4 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 424.0
HKD2_k127_4028967_5 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001872 258.0
HKD2_k127_4028967_6 - - - - 0.00000000000000000000000000000000000000000000000000001252 192.0
HKD2_k127_4028967_8 - - - - 0.0000000000000000000000000000000000000007348 156.0
HKD2_k127_4028967_9 Transposase K07491 - - 0.00000000000000000007866 91.0
HKD2_k127_4050532_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000007092 241.0
HKD2_k127_4050532_1 - - - - 0.000000000000000000000000000000001653 130.0
HKD2_k127_4050532_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000116 69.0
HKD2_k127_4065512_0 CBS domain containing protein K00974 - 2.7.7.72 0.0 1423.0
HKD2_k127_4065512_1 AAA domain K03546 - - 0.0 1173.0
HKD2_k127_4065512_10 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 591.0
HKD2_k127_4065512_11 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 580.0
HKD2_k127_4065512_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 589.0
HKD2_k127_4065512_13 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 557.0
HKD2_k127_4065512_14 PFAM phosphate acetyl butaryl transferase K00625,K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 556.0
HKD2_k127_4065512_15 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 542.0
HKD2_k127_4065512_16 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 451.0
HKD2_k127_4065512_17 Sensor histidine kinase, PAS, PAS, PAS and PAS domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 426.0
HKD2_k127_4065512_18 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 404.0
HKD2_k127_4065512_19 GGDEF domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 402.0
HKD2_k127_4065512_2 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0 1030.0
HKD2_k127_4065512_20 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 389.0
HKD2_k127_4065512_21 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 376.0
HKD2_k127_4065512_22 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 320.0
HKD2_k127_4065512_23 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
HKD2_k127_4065512_24 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000001853 266.0
HKD2_k127_4065512_25 PFAM MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001452 252.0
HKD2_k127_4065512_26 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000002843 229.0
HKD2_k127_4065512_27 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000005147 203.0
HKD2_k127_4065512_28 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.000000000000000000000000000000000000000001584 158.0
HKD2_k127_4065512_29 - - - - 0.0000000000000000000000000000000005312 134.0
HKD2_k127_4065512_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.557e-266 829.0
HKD2_k127_4065512_30 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000199 105.0
HKD2_k127_4065512_31 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000000006061 100.0
HKD2_k127_4065512_32 - - - - 0.00000000000000000766 84.0
HKD2_k127_4065512_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 3.279e-260 803.0
HKD2_k127_4065512_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.325e-257 797.0
HKD2_k127_4065512_6 SMART Nucleotide binding protein, PINc K07175 - - 2.452e-257 798.0
HKD2_k127_4065512_7 Calcineurin-like phosphoesterase K03547 - - 3.337e-206 652.0
HKD2_k127_4065512_8 MoeA domain protein domain I and II K03750 - 2.10.1.1 5.78e-199 625.0
HKD2_k127_4065512_9 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 591.0
HKD2_k127_407527_0 P22 coat protein-protein 5 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
HKD2_k127_407527_1 Phage gp6-like head-tail connector protein - - - 0.0000000004379 64.0
HKD2_k127_407527_2 Domain of unknown function (DUF4355) - - - 0.0002295 48.0
HKD2_k127_4079791_0 - - - - 0.000000000000000000000000000004033 121.0
HKD2_k127_4079791_1 - - - - 0.00000000000000000000001043 105.0
HKD2_k127_4079791_10 - - - - 0.000000000165 64.0
HKD2_k127_4079791_12 - - - - 0.0004132 44.0
HKD2_k127_4079791_13 - - - - 0.0004827 43.0
HKD2_k127_4079791_2 - - - - 0.0000000000000000004629 86.0
HKD2_k127_4079791_3 - - - - 0.000000000000000002489 86.0
HKD2_k127_4079791_4 - - - - 0.00000000000000001483 88.0
HKD2_k127_4079791_5 mitotic sister chromatid biorientation - - - 0.00000000000000006715 79.0
HKD2_k127_4079791_6 - - - - 0.00000000000000007479 79.0
HKD2_k127_4079791_7 - - - - 0.000000000000006096 74.0
HKD2_k127_4082288_0 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 377.0
HKD2_k127_4092419_0 IS630 family ISRj1-like transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 363.0
HKD2_k127_4092419_1 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 287.0
HKD2_k127_4092419_2 SPTR A7NFQ2 Transposase and inactivated derivatives-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006336 281.0
HKD2_k127_4092419_3 Helix-turn-helix domain - - - 0.00000000000000000002329 101.0
HKD2_k127_4094281_0 AMP-binding enzyme C-terminal domain K12507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 571.0
HKD2_k127_4094281_1 Short-chain dehydrogenase reductase (SDR) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 325.0
HKD2_k127_4094281_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000025 240.0
HKD2_k127_4094281_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 235.0
HKD2_k127_4094281_4 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000001261 65.0
HKD2_k127_4094281_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000001712 65.0
HKD2_k127_4096218_0 hmm pf01520 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000002514 172.0
HKD2_k127_4096218_1 - - - - 0.00000000000000000000000009562 108.0
HKD2_k127_4096218_2 cellulose 1,4-beta-cellobiosidase activity - - - 0.00000000000000000001702 108.0
HKD2_k127_4101889_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 2.083e-250 777.0
HKD2_k127_4101889_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 3.72e-196 621.0
HKD2_k127_4101889_10 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001598 261.0
HKD2_k127_4101889_2 Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 528.0
HKD2_k127_4101889_3 PFAM ABC transporter related K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 452.0
HKD2_k127_4101889_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 448.0
HKD2_k127_4101889_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 402.0
HKD2_k127_4101889_6 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 403.0
HKD2_k127_4101889_7 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 341.0
HKD2_k127_4101889_9 belongs to the Fur family K02076,K03711,K09823 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010043,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0046872,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005178 262.0
HKD2_k127_4107262_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1313.0
HKD2_k127_4107262_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1155.0
HKD2_k127_4107262_10 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000001861 60.0
HKD2_k127_4107262_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 997.0
HKD2_k127_4107262_3 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 559.0
HKD2_k127_4107262_4 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 389.0
HKD2_k127_4107262_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 372.0
HKD2_k127_4107262_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 323.0
HKD2_k127_4107262_8 ACT domain K03567 - - 0.0000000000000000000001228 104.0
HKD2_k127_4112974_0 GMC oxidoreductase - - - 0.0 1030.0
HKD2_k127_4112974_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 591.0
HKD2_k127_4112974_10 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 302.0
HKD2_k127_4112974_11 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 302.0
HKD2_k127_4112974_12 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 282.0
HKD2_k127_4112974_13 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000008702 241.0
HKD2_k127_4112974_14 Sugar efflux transporter for intercellular exchange K15383 - - 0.00000000000000000000000000000007639 127.0
HKD2_k127_4112974_15 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000003721 106.0
HKD2_k127_4112974_16 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000004487 107.0
HKD2_k127_4112974_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 540.0
HKD2_k127_4112974_3 HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 494.0
HKD2_k127_4112974_4 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 461.0
HKD2_k127_4112974_5 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 453.0
HKD2_k127_4112974_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 445.0
HKD2_k127_4112974_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 424.0
HKD2_k127_4112974_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 359.0
HKD2_k127_4112974_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 309.0
HKD2_k127_4141136_0 Histidine kinase - - - 4.215e-287 900.0
HKD2_k127_4141136_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 3.621e-260 809.0
HKD2_k127_4141136_2 TIGRFAM MATE efflux family protein K03327 - - 7.967e-234 730.0
HKD2_k127_4141136_3 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 615.0
HKD2_k127_4141136_4 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 602.0
HKD2_k127_4141136_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 584.0
HKD2_k127_4141136_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 426.0
HKD2_k127_4141136_7 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000852 276.0
HKD2_k127_4141136_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
HKD2_k127_4141136_9 - - - - 0.0000000000000000000000000000000000000007976 150.0
HKD2_k127_4154486_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1455.0
HKD2_k127_4154486_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1135.0
HKD2_k127_4154486_10 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 3.698e-217 685.0
HKD2_k127_4154486_11 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 606.0
HKD2_k127_4154486_12 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 507.0
HKD2_k127_4154486_13 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 473.0
HKD2_k127_4154486_14 integrase domain protein SAM domain protein K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 475.0
HKD2_k127_4154486_15 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 447.0
HKD2_k127_4154486_16 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 447.0
HKD2_k127_4154486_17 PFAM Polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 413.0
HKD2_k127_4154486_18 eight transmembrane protein EpsH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 413.0
HKD2_k127_4154486_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 404.0
HKD2_k127_4154486_2 TPR repeat-containing protein - - - 0.0 1120.0
HKD2_k127_4154486_20 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 394.0
HKD2_k127_4154486_21 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 371.0
HKD2_k127_4154486_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 366.0
HKD2_k127_4154486_23 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 361.0
HKD2_k127_4154486_24 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 378.0
HKD2_k127_4154486_25 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 346.0
HKD2_k127_4154486_26 Pfam:Methyltransf_26 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 315.0
HKD2_k127_4154486_27 Crp-like helix-turn-helix domain K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 312.0
HKD2_k127_4154486_28 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 305.0
HKD2_k127_4154486_29 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
HKD2_k127_4154486_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 4.659e-316 971.0
HKD2_k127_4154486_30 TIGRFAM EpsI family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 302.0
HKD2_k127_4154486_31 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004006 290.0
HKD2_k127_4154486_32 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005882 248.0
HKD2_k127_4154486_33 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005196 260.0
HKD2_k127_4154486_34 Protein of unknown function (DUF642) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007079 239.0
HKD2_k127_4154486_35 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
HKD2_k127_4154486_36 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000001478 239.0
HKD2_k127_4154486_37 Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane K11941 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0008150,GO:0008152,GO:0009311,GO:0016020,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0044238,GO:0044464,GO:0071704,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000008411 228.0
HKD2_k127_4154486_38 Glycosyltransferase like family 2 K07011,K20444 - - 0.0000000000000000000000000000000000000000000000000000000007036 211.0
HKD2_k127_4154486_39 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000001513 216.0
HKD2_k127_4154486_4 PFAM ATP-binding region, ATPase domain protein - - - 1.874e-291 908.0
HKD2_k127_4154486_40 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000000000000000000000115 192.0
HKD2_k127_4154486_41 transferase activity, transferring amino-acyl groups - - - 0.00000000000000000000000000000000000000000000004497 178.0
HKD2_k127_4154486_42 Chorismate mutase type II K04093 - 5.4.99.5 0.000000000000000000000000000000000000000001893 158.0
HKD2_k127_4154486_43 PKD domain - - - 0.0000000000000000000000000000000000003166 163.0
HKD2_k127_4154486_44 Acetyltransferase - - - 0.000000000000000000000000000000000000774 148.0
HKD2_k127_4154486_45 PKD domain - - - 0.0000000000000000000000000000000002143 151.0
HKD2_k127_4154486_46 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000005287 142.0
HKD2_k127_4154486_47 xylanase chitin deacetylase - - - 0.000000000000000000000000000002102 134.0
HKD2_k127_4154486_49 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000005639 98.0
HKD2_k127_4154486_5 Aminotransferase class I and II - - - 2.558e-274 846.0
HKD2_k127_4154486_50 Domain of unknown function (DUF1858) - - - 0.00000000000000000000105 101.0
HKD2_k127_4154486_51 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000001324 64.0
HKD2_k127_4154486_52 UbiA prenyltransferase family - - - 0.000002104 50.0
HKD2_k127_4154486_53 O-Antigen ligase - - - 0.000004255 59.0
HKD2_k127_4154486_54 - - - - 0.000004433 51.0
HKD2_k127_4154486_55 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0002987 53.0
HKD2_k127_4154486_6 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 6.987e-223 693.0
HKD2_k127_4154486_7 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 1.34e-221 693.0
HKD2_k127_4154486_8 Proposed homoserine kinase K15635 - 5.4.2.12 1.401e-221 692.0
HKD2_k127_4154486_9 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 2.727e-218 694.0
HKD2_k127_4163177_0 GTP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 381.0
HKD2_k127_4181342_0 Phage tail tape measure protein, TP901 family - - - 0.000000000000000000000000000000000002728 150.0
HKD2_k127_4181342_1 Phage minor structural protein - - - 0.00000000000000000000000000000000001101 147.0
HKD2_k127_4181342_2 Phage tail tape measure protein, TP901 family - - - 0.0002028 52.0
HKD2_k127_4188511_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1363.0
HKD2_k127_4188511_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0 1124.0
HKD2_k127_4188511_10 GGGtGRT protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 567.0
HKD2_k127_4188511_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 532.0
HKD2_k127_4188511_12 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 511.0
HKD2_k127_4188511_13 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 424.0
HKD2_k127_4188511_14 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 421.0
HKD2_k127_4188511_15 Uncharacterised protein family (UPF0014) K02069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 391.0
HKD2_k127_4188511_16 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 351.0
HKD2_k127_4188511_17 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 318.0
HKD2_k127_4188511_18 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 314.0
HKD2_k127_4188511_19 abc transporter atp-binding protein K02065,K02068,K02071,K05773,K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
HKD2_k127_4188511_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 1.332e-262 811.0
HKD2_k127_4188511_20 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000003306 262.0
HKD2_k127_4188511_21 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000000000000000000000000005522 206.0
HKD2_k127_4188511_22 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000000000000000000000001261 212.0
HKD2_k127_4188511_23 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000000000000000000005267 177.0
HKD2_k127_4188511_24 Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000001157 172.0
HKD2_k127_4188511_25 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000000001837 154.0
HKD2_k127_4188511_26 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000004411 118.0
HKD2_k127_4188511_27 glutathione-regulated potassium exporter activity - - - 0.000000000000000000009818 94.0
HKD2_k127_4188511_28 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001294 88.0
HKD2_k127_4188511_29 - - - - 0.0000009344 50.0
HKD2_k127_4188511_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.564e-251 778.0
HKD2_k127_4188511_30 PFAM Sodium hydrogen exchanger family K03455 - - 0.0001847 45.0
HKD2_k127_4188511_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 7.855e-247 767.0
HKD2_k127_4188511_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.228e-237 745.0
HKD2_k127_4188511_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 4.222e-211 659.0
HKD2_k127_4188511_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 2.624e-206 651.0
HKD2_k127_4188511_8 Voltage gated chloride channel - - - 1.594e-198 636.0
HKD2_k127_4188511_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 607.0
HKD2_k127_419111_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008888 291.0
HKD2_k127_419111_1 - - - - 0.000007896 51.0
HKD2_k127_4195229_0 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 457.0
HKD2_k127_4195229_1 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000000000000004785 141.0
HKD2_k127_4195748_0 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 547.0
HKD2_k127_4195748_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 306.0
HKD2_k127_4195748_2 Domain of unknown function (DUF2383) - - - 0.00000000000000000000000000000000000000000000001462 175.0
HKD2_k127_4218578_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 4.46e-210 659.0
HKD2_k127_4218578_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000004412 222.0
HKD2_k127_4218578_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.0000000000000000000000000000000000000000000000000000000002166 205.0
HKD2_k127_4218578_3 4Fe-4S dicluster domain K14091 - - 0.00000000000000000000000000000000000000000000001218 175.0
HKD2_k127_4239278_0 PFAM Acetyl-CoA hydrolase transferase K01067,K18118 - 2.8.3.18,3.1.2.1 0.0 1009.0
HKD2_k127_4239278_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 425.0
HKD2_k127_4239278_2 PFAM regulatory protein TetR K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
HKD2_k127_4239278_3 Transcriptional regulator - - - 0.0000000000000000001863 92.0
HKD2_k127_4239278_4 protein conserved in bacteria - - - 0.00000000000000003022 81.0
HKD2_k127_425612_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1348.0
HKD2_k127_425612_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.179e-259 800.0
HKD2_k127_425612_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 591.0
HKD2_k127_425612_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 383.0
HKD2_k127_425612_4 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 296.0
HKD2_k127_4272245_0 PFAM chemotaxis sensory transducer - - - 1.79e-222 703.0
HKD2_k127_4272245_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 558.0
HKD2_k127_4272245_2 Transcriptional regulator, marR - - - 0.0000000000000000000000000000000000000000000000000000000000000001254 225.0
HKD2_k127_4272245_3 drug resistance transporter, Bcr CflA K07552 - - 0.00000000000000000000000000000000000008543 143.0
HKD2_k127_4317679_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K00595 - 2.1.1.132 2.114e-250 775.0
HKD2_k127_4317679_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 420.0
HKD2_k127_4317679_2 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 419.0
HKD2_k127_4317679_3 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000006766 166.0
HKD2_k127_4343835_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0 1442.0
HKD2_k127_4343835_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 445.0
HKD2_k127_4343835_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 434.0
HKD2_k127_4343835_3 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 380.0
HKD2_k127_4343835_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 290.0
HKD2_k127_4343835_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000002722 219.0
HKD2_k127_4380253_0 - - - - 0.0000000000000000000000000000000000000001871 152.0
HKD2_k127_4380253_1 - - - - 0.0000000000002763 70.0
HKD2_k127_4380253_2 - - - - 0.0000000000009274 67.0
HKD2_k127_4390840_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 487.0
HKD2_k127_4390840_1 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 309.0
HKD2_k127_4390840_2 Sporulation and spore germination - - - 0.0000000000000000000000000000000000000000000002726 173.0
HKD2_k127_4390840_3 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.000000000000005975 79.0
HKD2_k127_4403646_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1555.0
HKD2_k127_4403646_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0 1036.0
HKD2_k127_4403646_10 GGDEF domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 416.0
HKD2_k127_4403646_11 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000366 274.0
HKD2_k127_4403646_12 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000002655 235.0
HKD2_k127_4403646_13 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000003153 230.0
HKD2_k127_4403646_14 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000000000000000000006301 222.0
HKD2_k127_4403646_15 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000007582 189.0
HKD2_k127_4403646_16 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000003584 163.0
HKD2_k127_4403646_17 TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 - - - 0.00000000000000000000000000000000006305 147.0
HKD2_k127_4403646_18 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000001082 68.0
HKD2_k127_4403646_19 Pfam:Arch_ATPase - - - 0.00000005937 54.0
HKD2_k127_4403646_2 regulator, PATAN and FRGAF domain-containing - - - 2.769e-255 802.0
HKD2_k127_4403646_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 8.84e-255 790.0
HKD2_k127_4403646_4 HEAT repeat - - - 3.288e-224 713.0
HKD2_k127_4403646_5 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 575.0
HKD2_k127_4403646_6 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 568.0
HKD2_k127_4403646_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 505.0
HKD2_k127_4403646_8 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 488.0
HKD2_k127_4403646_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 450.0
HKD2_k127_4403647_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.339e-233 726.0
HKD2_k127_4403647_1 PFAM Class II aldolase K01628 - 4.1.2.17 4.031e-199 625.0
HKD2_k127_4403647_2 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000004183 69.0
HKD2_k127_4426698_0 Alpha amylase, catalytic domain - - - 0.0 1051.0
HKD2_k127_4426698_1 gluconate transmembrane transporter activity - - - 5.262e-204 642.0
HKD2_k127_4426698_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 439.0
HKD2_k127_4426698_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000008875 212.0
HKD2_k127_4426698_5 peptidyl-prolyl cis-trans isomerase activity K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000001499 192.0
HKD2_k127_4426698_6 DNA mediated transformation - - - 0.00000000000000000000000000000000000000000000002472 175.0
HKD2_k127_4426698_7 - - - - 0.0000000000000000000000000000000000000000001789 168.0
HKD2_k127_4426698_8 Carbohydrate/starch-binding module (family 21) - - - 0.0000000000000000003985 96.0
HKD2_k127_4486814_0 malic protein domain protein K00029 - 1.1.1.40 0.0 1266.0
HKD2_k127_4486814_1 4Fe-4S dicluster domain - - - 0.0 1154.0
HKD2_k127_4486814_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 582.0
HKD2_k127_4486814_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 470.0
HKD2_k127_4486814_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 427.0
HKD2_k127_4486814_5 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 341.0
HKD2_k127_4486814_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 342.0
HKD2_k127_4486814_7 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000001424 77.0
HKD2_k127_4503732_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1692.0
HKD2_k127_4503732_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1642.0
HKD2_k127_4503732_10 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 402.0
HKD2_k127_4503732_11 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 372.0
HKD2_k127_4503732_12 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 351.0
HKD2_k127_4503732_13 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 312.0
HKD2_k127_4503732_14 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005281 281.0
HKD2_k127_4503732_15 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000455 254.0
HKD2_k127_4503732_16 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000222 242.0
HKD2_k127_4503732_17 - - - - 0.0000000000000000000000000000000000000000000000000000000003747 209.0
HKD2_k127_4503732_19 Pilus assembly protein, PilP K02665 - - 0.000000000000000000000000000000000000000000000003289 179.0
HKD2_k127_4503732_2 outer membrane autotransporter barrel domain - - - 0.0 1461.0
HKD2_k127_4503732_20 - - - - 0.0000000000000000000000000000000000000000000009947 175.0
HKD2_k127_4503732_21 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000002443 150.0
HKD2_k127_4503732_22 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000005728 132.0
HKD2_k127_4503732_23 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000000007664 122.0
HKD2_k127_4503732_24 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000002173 118.0
HKD2_k127_4503732_25 Pfam:N_methyl_2 K02671 - - 0.00000000001005 70.0
HKD2_k127_4503732_27 Prokaryotic N-terminal methylation motif - - - 0.000001045 55.0
HKD2_k127_4503732_3 PFAM type II and III secretion system protein K02666 - - 0.0 1206.0
HKD2_k127_4503732_4 Tfp pilus assembly protein tip-associated adhesin K02674 - - 9.666e-281 949.0
HKD2_k127_4503732_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 4.403e-204 640.0
HKD2_k127_4503732_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 5.417e-197 619.0
HKD2_k127_4503732_7 PFAM beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 585.0
HKD2_k127_4503732_8 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 574.0
HKD2_k127_4503732_9 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 437.0
HKD2_k127_4543434_0 IS116 IS110 IS902 family - - - 3.848e-196 614.0
HKD2_k127_4598952_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1417.0
HKD2_k127_4598952_1 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 1.157e-259 804.0
HKD2_k127_4598952_2 Participates in both transcription termination and antitermination K02600 - - 8.516e-218 679.0
HKD2_k127_4598952_3 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 331.0
HKD2_k127_4598952_4 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 322.0
HKD2_k127_4598952_5 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000002048 241.0
HKD2_k127_4598952_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000003096 128.0
HKD2_k127_4618670_0 Helix-turn-helix domain of transposase family ISL3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 407.0
HKD2_k127_462193_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000004408 230.0
HKD2_k127_463722_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 469.0
HKD2_k127_463722_1 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 419.0
HKD2_k127_4685846_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0 1184.0
HKD2_k127_4685846_1 response regulator K07712 - - 6.072e-286 883.0
HKD2_k127_4685846_10 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 351.0
HKD2_k127_4685846_11 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 302.0
HKD2_k127_4685846_12 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 296.0
HKD2_k127_4685846_13 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000001556 239.0
HKD2_k127_4685846_14 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000001952 223.0
HKD2_k127_4685846_15 Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000007235 182.0
HKD2_k127_4685846_16 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000000000000429 134.0
HKD2_k127_4685846_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 9.043e-264 815.0
HKD2_k127_4685846_3 Fumarase C C-terminus K01744 - 4.3.1.1 1.135e-237 741.0
HKD2_k127_4685846_4 - - - - 7.805e-227 709.0
HKD2_k127_4685846_5 Phospholipase D. Active site motifs. K06131 - - 1.623e-203 638.0
HKD2_k127_4685846_6 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 6.461e-197 618.0
HKD2_k127_4685846_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 545.0
HKD2_k127_4685846_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 537.0
HKD2_k127_4685846_9 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 392.0
HKD2_k127_4747495_0 transaminase activity K16423 - 2.6.1.103 0.0000000000001113 78.0
HKD2_k127_475934_0 N-acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000000009684 175.0
HKD2_k127_475934_1 Transglycosylase SLT domain - - - 0.000000001338 73.0
HKD2_k127_475934_2 Papain family cysteine protease - - - 0.0009923 43.0
HKD2_k127_4802372_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K14086 - - 2.012e-311 963.0
HKD2_k127_4802372_1 Phosphofructokinase K00850 - 2.7.1.11 2.38e-220 689.0
HKD2_k127_4802372_2 NADH dehydrogenase K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 483.0
HKD2_k127_4802372_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 282.0
HKD2_k127_4802372_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000003395 128.0
HKD2_k127_4812188_0 Endodeoxyribonuclease RusA - - - 0.000006976 50.0
HKD2_k127_482393_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1877.0
HKD2_k127_482393_1 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.0 1412.0
HKD2_k127_482393_10 fibronectin type III domain protein - - - 0.00000006489 53.0
HKD2_k127_482393_2 HisKA, HATPase_c - - - 1.051e-247 784.0
HKD2_k127_482393_3 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 2.793e-203 655.0
HKD2_k127_482393_4 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 4.453e-197 627.0
HKD2_k127_482393_5 Nitrite and sulphite reductase 4Fe-4S domain K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 602.0
HKD2_k127_482393_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 462.0
HKD2_k127_482393_7 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 425.0
HKD2_k127_482393_8 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 395.0
HKD2_k127_482393_9 Pyridoxamine 5'-phosphate oxidase K07006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000256 201.0
HKD2_k127_4826166_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1322.0
HKD2_k127_4826166_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1157.0
HKD2_k127_4826166_2 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 561.0
HKD2_k127_4826166_3 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 446.0
HKD2_k127_4826166_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000346 255.0
HKD2_k127_4826166_5 SpoIIAA-like - - - 0.00000000000000000000000000000000000000271 150.0
HKD2_k127_4855721_0 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 317.0
HKD2_k127_4855721_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000004788 173.0
HKD2_k127_4877678_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0 1063.0
HKD2_k127_4877678_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0 1032.0
HKD2_k127_4877678_10 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000000008379 168.0
HKD2_k127_4877678_11 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000000001035 128.0
HKD2_k127_4877678_12 protein secretion K03116 - - 0.0000000000000000000002098 97.0
HKD2_k127_4877678_2 PFAM Polysulphide reductase, NrfD - - - 4.854e-249 773.0
HKD2_k127_4877678_3 Histidine kinase HAMP K02482 - 2.7.13.3 7.568e-245 774.0
HKD2_k127_4877678_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 1.418e-223 700.0
HKD2_k127_4877678_5 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 1.295e-221 689.0
HKD2_k127_4877678_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 604.0
HKD2_k127_4877678_7 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 410.0
HKD2_k127_4877678_8 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002027 270.0
HKD2_k127_4877678_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005074 263.0
HKD2_k127_493979_0 FtsX-like permease family K02004 - - 0.0 1119.0
HKD2_k127_493979_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 1.745e-269 833.0
HKD2_k127_493979_10 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000209 100.0
HKD2_k127_493979_12 - - - - 0.0000001262 57.0
HKD2_k127_493979_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 529.0
HKD2_k127_493979_3 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 516.0
HKD2_k127_493979_4 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 431.0
HKD2_k127_493979_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 375.0
HKD2_k127_493979_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 351.0
HKD2_k127_493979_7 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 326.0
HKD2_k127_493979_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004327 278.0
HKD2_k127_493979_9 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000008865 224.0
HKD2_k127_50009_0 Homeodomain-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 531.0
HKD2_k127_50009_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003476 243.0
HKD2_k127_5126263_0 amine oxidase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 591.0
HKD2_k127_5126263_1 heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 490.0
HKD2_k127_5126263_11 - - - - 0.000000000001273 72.0
HKD2_k127_5126263_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 500.0
HKD2_k127_5126263_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 418.0
HKD2_k127_5126263_4 Protein of unknown function (DUF3187) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 347.0
HKD2_k127_5126263_5 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000000000000000000000000002812 218.0
HKD2_k127_5126263_6 Thioesterase-like superfamily K02614 - - 0.000000000000000000000000000000000000000000000000000000003423 202.0
HKD2_k127_5126263_7 Elongation factor - - - 0.00000000000000000000000000000000000000000000000000000007344 199.0
HKD2_k127_5126263_8 NTPase - - - 0.0000000000000000000000000000000000000000001425 164.0
HKD2_k127_5126263_9 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000000007925 108.0
HKD2_k127_5132023_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000998 508.0
HKD2_k127_5132023_1 positive regulation of growth - - - 0.00000002866 59.0
HKD2_k127_5132404_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1081.0
HKD2_k127_5132404_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 589.0
HKD2_k127_5132404_2 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 469.0
HKD2_k127_5132404_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 432.0
HKD2_k127_5132404_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 352.0
HKD2_k127_5132404_5 - - - - 0.0000000001514 63.0
HKD2_k127_5142169_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.17.1.10 0.0 1240.0
HKD2_k127_5142169_1 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0 1205.0
HKD2_k127_5142169_10 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 567.0
HKD2_k127_5142169_11 SMART Elongator protein 3 MiaB NifB K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 559.0
HKD2_k127_5142169_12 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 531.0
HKD2_k127_5142169_13 12 heme-binding sites - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 522.0
HKD2_k127_5142169_14 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 505.0
HKD2_k127_5142169_15 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 506.0
HKD2_k127_5142169_16 Nitrate TMAO reductase, membrane-bound tetraheme cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 493.0
HKD2_k127_5142169_17 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 474.0
HKD2_k127_5142169_18 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 436.0
HKD2_k127_5142169_19 Histidine kinase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 404.0
HKD2_k127_5142169_2 Heat shock 70 kDa protein K04043 - - 0.0 1155.0
HKD2_k127_5142169_20 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 392.0
HKD2_k127_5142169_21 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 388.0
HKD2_k127_5142169_22 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 385.0
HKD2_k127_5142169_23 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 363.0
HKD2_k127_5142169_24 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 359.0
HKD2_k127_5142169_25 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 300.0
HKD2_k127_5142169_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 291.0
HKD2_k127_5142169_28 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001877 267.0
HKD2_k127_5142169_29 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
HKD2_k127_5142169_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 1148.0
HKD2_k127_5142169_30 TonB C terminal K03646,K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002322 254.0
HKD2_k127_5142169_31 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000005143 239.0
HKD2_k127_5142169_32 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000000000000000000000000008319 235.0
HKD2_k127_5142169_33 phosphorelay signal transduction system K03974 - - 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
HKD2_k127_5142169_35 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000002957 140.0
HKD2_k127_5142169_38 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000000000000000003528 119.0
HKD2_k127_5142169_4 response regulator - - - 1.593e-263 818.0
HKD2_k127_5142169_40 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000001746 108.0
HKD2_k127_5142169_41 - - - - 0.00000000000000000001541 93.0
HKD2_k127_5142169_5 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.145e-261 808.0
HKD2_k127_5142169_6 histidine kinase, HAMP K02482 - 2.7.13.3 1.404e-250 784.0
HKD2_k127_5142169_7 two component, sigma54 specific, transcriptional regulator K02481 - - 2.847e-239 746.0
HKD2_k127_5142169_8 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 2.816e-204 641.0
HKD2_k127_5142169_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 570.0
HKD2_k127_5147235_0 Iron hydrogenase small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 0.0 1057.0
HKD2_k127_5147235_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K14086 - - 7.5e-322 995.0
HKD2_k127_5147235_10 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 526.0
HKD2_k127_5147235_11 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 508.0
HKD2_k127_5147235_12 NADH dehydrogenase K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 490.0
HKD2_k127_5147235_13 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 469.0
HKD2_k127_5147235_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 446.0
HKD2_k127_5147235_15 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 405.0
HKD2_k127_5147235_16 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 338.0
HKD2_k127_5147235_17 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 301.0
HKD2_k127_5147235_18 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 299.0
HKD2_k127_5147235_19 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007656 286.0
HKD2_k127_5147235_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 9.393e-317 985.0
HKD2_k127_5147235_20 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006775 235.0
HKD2_k127_5147235_21 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.000000000000000000000000000000000000000000000000000000000000002285 219.0
HKD2_k127_5147235_22 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000000000000003146 175.0
HKD2_k127_5147235_23 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000000000000000000008154 172.0
HKD2_k127_5147235_24 4Fe-4S dicluster domain K14091 - - 0.0000000000000000000000000000000000000000001329 162.0
HKD2_k127_5147235_25 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000006428 157.0
HKD2_k127_5147235_26 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000000000506 124.0
HKD2_k127_5147235_27 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000001144 124.0
HKD2_k127_5147235_3 Respiratory-chain NADH dehydrogenase 51 Kd subunit K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 2.708e-288 888.0
HKD2_k127_5147235_4 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 1.292e-257 803.0
HKD2_k127_5147235_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.28e-240 745.0
HKD2_k127_5147235_6 Fumarase C C-terminus K01744 - 4.3.1.1 5.838e-232 727.0
HKD2_k127_5147235_7 Ferrous iron transport protein B - - - 5.907e-212 666.0
HKD2_k127_5147235_8 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 8.479e-209 652.0
HKD2_k127_5147235_9 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 554.0
HKD2_k127_5151777_0 DNA-sulfur modification-associated K19169 - - 0.0001721 52.0
HKD2_k127_5161397_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 4.344e-240 756.0
HKD2_k127_5161397_1 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 6.405e-220 688.0
HKD2_k127_5161397_11 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000006451 89.0
HKD2_k127_5161397_2 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001169 287.0
HKD2_k127_5161397_3 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000007016 228.0
HKD2_k127_5161397_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000002742 183.0
HKD2_k127_5161397_6 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000002679 163.0
HKD2_k127_5161397_7 Low affinity iron permease - - - 0.0000000000000000000000000000000000000001098 154.0
HKD2_k127_5161397_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000003959 129.0
HKD2_k127_5161397_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000001372 122.0
HKD2_k127_5171020_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1534.0
HKD2_k127_5171020_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1175.0
HKD2_k127_5171020_2 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 1.026e-203 651.0
HKD2_k127_5171020_3 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 407.0
HKD2_k127_5171020_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 404.0
HKD2_k127_5171020_5 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009648 265.0
HKD2_k127_5171020_6 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000002191 167.0
HKD2_k127_5171020_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000522 106.0
HKD2_k127_5177973_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1954.0
HKD2_k127_5177973_1 type II and III secretion system protein K02453 - - 0.0 1051.0
HKD2_k127_5177973_11 General secretory system II, protein E domain protein K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 304.0
HKD2_k127_5177973_12 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 300.0
HKD2_k127_5177973_13 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 301.0
HKD2_k127_5177973_14 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000007836 184.0
HKD2_k127_5177973_16 PFAM Fimbrial assembly family protein K02663 - - 0.0000000000000000000000000000000000000000000000004924 181.0
HKD2_k127_5177973_18 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000000000000000000000000001938 167.0
HKD2_k127_5177973_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 8.46e-274 846.0
HKD2_k127_5177973_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.948e-260 805.0
HKD2_k127_5177973_4 PFAM Peptidase M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 569.0
HKD2_k127_5177973_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 518.0
HKD2_k127_5177973_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 467.0
HKD2_k127_5177973_7 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 447.0
HKD2_k127_5177973_8 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 423.0
HKD2_k127_5177973_9 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 398.0
HKD2_k127_5204142_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0 996.0
HKD2_k127_5204142_1 PFAM Cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 6.41e-244 760.0
HKD2_k127_5204142_2 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 314.0
HKD2_k127_5204142_3 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008086 236.0
HKD2_k127_5204142_4 Helix-hairpin-helix motif K02237 - - 0.000000000000000000000000000000000000000000000000000000000001007 218.0
HKD2_k127_5204142_5 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000001274 181.0
HKD2_k127_5204142_6 - - - - 0.000000000000000000000000000007275 118.0
HKD2_k127_5218174_0 Belongs to the NifD NifK NifE NifN family K02587 - - 0.0 1678.0
HKD2_k127_5218174_1 4Fe-4S dicluster domain - - - 2e-323 999.0
HKD2_k127_5218174_10 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 481.0
HKD2_k127_5218174_11 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 461.0
HKD2_k127_5218174_12 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 336.0
HKD2_k127_5218174_13 Pfam Dinitrogenase iron-molybdenum cofactor K02596 - - 0.000000000000000000000000000000000000000000000000000000000000000000001398 239.0
HKD2_k127_5218174_14 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000004447 191.0
HKD2_k127_5218174_15 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000002706 179.0
HKD2_k127_5218174_16 unfolded protein binding K06142 - - 0.0000000000000000000000000000000000000007075 156.0
HKD2_k127_5218174_18 Protein of unknown function (DUF2844) - - - 0.0000008284 57.0
HKD2_k127_5218174_2 Nitrogenase component 1 type Oxidoreductase K02586 - 1.18.6.1 4.039e-319 978.0
HKD2_k127_5218174_3 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 5.926e-318 974.0
HKD2_k127_5218174_4 electron transfer flavoprotein, alpha subunit K03522 - - 7.714e-241 748.0
HKD2_k127_5218174_5 PFAM Peptidase S10, serine carboxypeptidase - - - 1.348e-222 700.0
HKD2_k127_5218174_6 Protein of unknown function (DUF3443) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 559.0
HKD2_k127_5218174_7 PFAM Dinitrogenase reductase ADP-ribosyltransferase K05951 - 2.4.2.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 502.0
HKD2_k127_5218174_8 PFAM ADP-ribosylation Crystallin J1 K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 497.0
HKD2_k127_5218174_9 SMART Elongator protein 3 MiaB NifB K02585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 498.0
HKD2_k127_5218409_0 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000007582 182.0
HKD2_k127_5218409_1 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.000000000002234 81.0
HKD2_k127_5218409_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000743 59.0
HKD2_k127_5229119_0 Belongs to the UbiD family K03182 - 4.1.1.98 7.029e-203 640.0
HKD2_k127_5229119_1 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 475.0
HKD2_k127_5229119_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000002094 235.0
HKD2_k127_5233260_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1182.0
HKD2_k127_5233260_1 Citrate lyase alpha subunit K01643 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.10 2.008e-293 904.0
HKD2_k127_5233260_10 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 295.0
HKD2_k127_5233260_11 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 325.0
HKD2_k127_5233260_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008028 293.0
HKD2_k127_5233260_13 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000003082 280.0
HKD2_k127_5233260_14 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
HKD2_k127_5233260_15 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849,K12982 - - 0.00000000000000000000000000000000000000000000000000001711 205.0
HKD2_k127_5233260_16 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000000009304 177.0
HKD2_k127_5233260_17 - - - - 0.0000000000000000000000000000000000001131 147.0
HKD2_k127_5233260_18 Covalent carrier of the coenzyme of citrate lyase K01646 - - 0.000000000000000000000000000000000006985 139.0
HKD2_k127_5233260_2 secondary active sulfate transmembrane transporter activity K06901 - - 1.098e-276 856.0
HKD2_k127_5233260_20 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase K05964 GO:0003674,GO:0003824,GO:0006091,GO:0006113,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016772,GO:0016779,GO:0018065,GO:0018193,GO:0018209,GO:0018246,GO:0018247,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050519,GO:0055114,GO:0071704,GO:1901564 2.7.7.61 0.000000000000000001347 91.0
HKD2_k127_5233260_3 PFAM Patatin K07001 - - 4.113e-219 691.0
HKD2_k127_5233260_4 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 8.374e-208 659.0
HKD2_k127_5233260_5 Carboxypeptidase Taq (M32) metallopeptidase K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 577.0
HKD2_k127_5233260_6 Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase K01910 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008771,GO:0009987,GO:0016874,GO:0016877,GO:0016878,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 6.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 488.0
HKD2_k127_5233260_7 PAS domain containing protein K07315,K07675 - 2.7.13.3,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 419.0
HKD2_k127_5233260_8 ATP:dephospho-CoA triphosphoribosyl transferase K05966,K13930 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 357.0
HKD2_k127_5233260_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 351.0
HKD2_k127_5242450_0 DNA polymerase alpha chain like domain K02347,K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
HKD2_k127_5247586_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 2.535e-221 696.0
HKD2_k127_5247586_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000000004074 129.0
HKD2_k127_5247586_2 Peptidase C10 family - - - 0.000000008964 59.0
HKD2_k127_5253575_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 9.225e-253 801.0
HKD2_k127_5255209_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 3.885e-206 649.0
HKD2_k127_5255209_2 Protein conserved in bacteria - - - 0.00000000001141 65.0
HKD2_k127_5255209_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000001197 58.0
HKD2_k127_5269213_1 SMART Elongator protein 3 MiaB NifB - - - 1.239e-288 893.0
HKD2_k127_5269213_10 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000002647 178.0
HKD2_k127_5269213_11 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000000000000006813 161.0
HKD2_k127_5269213_12 - - - - 0.0000000000000000000000000000000000000001999 151.0
HKD2_k127_5269213_14 cell envelope organization K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000001583 111.0
HKD2_k127_5269213_15 - - - - 0.000000000000000002369 95.0
HKD2_k127_5269213_2 PFAM Xanthine uracil vitamin C permease K06901 - - 9.218e-241 748.0
HKD2_k127_5269213_3 AAA domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 458.0
HKD2_k127_5269213_4 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 407.0
HKD2_k127_5269213_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 386.0
HKD2_k127_5269213_6 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 354.0
HKD2_k127_5269213_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 321.0
HKD2_k127_5269213_8 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001659 274.0
HKD2_k127_5269213_9 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000799 209.0
HKD2_k127_5277955_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1489.0
HKD2_k127_5277955_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 525.0
HKD2_k127_5277955_2 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 470.0
HKD2_k127_5277955_3 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 305.0
HKD2_k127_5277955_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000001347 213.0
HKD2_k127_5277955_5 - - - - 0.00000000000000000000000000000000001544 136.0
HKD2_k127_5277955_7 - - - - 0.000000000000000000000005497 101.0
HKD2_k127_5277955_8 - - - - 0.0000000000000000000758 90.0
HKD2_k127_528131_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 9.865e-229 709.0
HKD2_k127_528131_1 PFAM cytochrome c class I - - - 0.0000000000000000000000000005094 115.0
HKD2_k127_5289400_0 Gaf domain K03406 - - 2.334e-270 839.0
HKD2_k127_5289400_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 346.0
HKD2_k127_5303580_0 response regulator K13599 - - 1.764e-267 826.0
HKD2_k127_5303580_1 Protein export membrane protein K07003 - - 1.18e-242 766.0
HKD2_k127_5303580_10 response regulator K01719,K22010 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004047 273.0
HKD2_k127_5303580_11 PFAM SEC-C motif domain protein K09858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 258.0
HKD2_k127_5303580_12 Outer membrane lipoprotein LolB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003659 259.0
HKD2_k127_5303580_13 FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000000000000000000000000003083 193.0
HKD2_k127_5303580_14 PFAM Stress responsive alpha-beta barrel - - - 0.0000000000000000000000000000000000000005002 150.0
HKD2_k127_5303580_2 PFAM aminotransferase, class I and II K11358 - 2.6.1.1 2.855e-227 707.0
HKD2_k127_5303580_3 CBS domain containing protein K03699 - - 1.012e-220 691.0
HKD2_k127_5303580_4 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 9.327e-204 642.0
HKD2_k127_5303580_5 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 483.0
HKD2_k127_5303580_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
HKD2_k127_5303580_7 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 461.0
HKD2_k127_5303580_8 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 418.0
HKD2_k127_5303580_9 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 280.0
HKD2_k127_5304210_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 493.0
HKD2_k127_5304210_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 462.0
HKD2_k127_5304210_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 383.0
HKD2_k127_5304210_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009734 354.0
HKD2_k127_5304210_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006805 244.0
HKD2_k127_5306536_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 4.534e-288 889.0
HKD2_k127_5313567_0 - - - - 4.59e-211 668.0
HKD2_k127_5325903_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 2.322e-194 610.0
HKD2_k127_5325903_1 Elongation factor P K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000266 245.0
HKD2_k127_5325903_2 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000000000000000000000000439 215.0
HKD2_k127_5325903_3 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000005053 197.0
HKD2_k127_5325903_4 PFAM RNA-binding S4 domain protein K14761 - - 0.00000000000000000000000000000000788 128.0
HKD2_k127_5325903_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000001301 61.0
HKD2_k127_5328382_0 Transposase DDE domain K07487 - - 5.282e-243 758.0
HKD2_k127_5328382_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000001435 219.0
HKD2_k127_5328382_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000008817 160.0
HKD2_k127_5328382_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000006648 93.0
HKD2_k127_5328382_4 RibD C-terminal domain - - - 0.000000000000000002946 84.0
HKD2_k127_5328382_5 PFAM Porin K16079 - - 0.000001816 53.0
HKD2_k127_5345184_0 histidine kinase HAMP region domain protein - - - 0.0 1045.0
HKD2_k127_5345184_1 denitrification pathway - - - 8.085e-233 734.0
HKD2_k127_5345184_3 - - - - 0.000000000000000000000000000000000000000000000000000002857 192.0
HKD2_k127_5345184_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000006819 101.0
HKD2_k127_5357145_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 4.111e-247 766.0
HKD2_k127_5357145_1 TIGRFAM carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 1.103e-236 733.0
HKD2_k127_5357145_2 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 557.0
HKD2_k127_5357145_3 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 514.0
HKD2_k127_5357145_4 Bifunctional protein PyrR K02825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 335.0
HKD2_k127_5363195_0 phage terminase, large subunit K06909 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 587.0
HKD2_k127_5363195_1 Phage portal protein, SPP1 Gp6-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001097 263.0
HKD2_k127_5363195_2 - - - - 0.0000000000000000000000000000000000000005759 150.0
HKD2_k127_5363195_3 - - - - 0.000000000000000000000000000004977 126.0
HKD2_k127_5363195_4 - - - - 0.000000000000000008249 88.0
HKD2_k127_5363195_5 NUMOD3 motif (2 copies) - - - 0.000003034 53.0
HKD2_k127_5363195_6 head morphogenesis protein, SPP1 gp7 family - - - 0.00001543 51.0
HKD2_k127_5373623_0 AcrB/AcrD/AcrF family K03296 - - 0.0 2430.0
HKD2_k127_5373623_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 6.358e-210 659.0
HKD2_k127_5373623_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 303.0
HKD2_k127_5373623_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
HKD2_k127_5373623_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003623 247.0
HKD2_k127_5373623_14 Diguanylate cyclase - - - 0.0000000857 53.0
HKD2_k127_5373623_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 564.0
HKD2_k127_5373623_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 552.0
HKD2_k127_5373623_4 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 523.0
HKD2_k127_5373623_5 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 443.0
HKD2_k127_5373623_6 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 408.0
HKD2_k127_5373623_7 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 393.0
HKD2_k127_5373623_8 cysteine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 375.0
HKD2_k127_5373623_9 Peptidase S24-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 322.0
HKD2_k127_5389769_0 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 344.0
HKD2_k127_5389769_1 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.0000000000000000000000000000000000000000000000000003518 188.0
HKD2_k127_5401877_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 439.0
HKD2_k127_5401877_1 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000001684 231.0
HKD2_k127_5401877_2 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.000000000002813 76.0
HKD2_k127_5407481_0 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000007947 234.0
HKD2_k127_5414190_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1394.0
HKD2_k127_5414190_1 PFAM ABC transporter related K06158 - - 0.0 1071.0
HKD2_k127_5414190_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 377.0
HKD2_k127_5414190_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 349.0
HKD2_k127_5414190_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000002011 209.0
HKD2_k127_5414190_5 HNH nucleases - - - 0.0000000000000000000000000000000000000000000004389 166.0
HKD2_k127_5424356_0 ResB protein required for cytochrome c biosynthesis K07399 - - 0.0000000001358 74.0
HKD2_k127_5424356_1 - - - - 0.00000003203 61.0
HKD2_k127_5424356_2 PFAM Trypsin - - - 0.0000006764 55.0
HKD2_k127_542553_0 Protein of unknown function (DUF3373) - - - 3.084e-285 884.0
HKD2_k127_542553_2 Belongs to the CinA family - - - 0.00000000002335 70.0
HKD2_k127_5437915_0 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 3.264e-300 926.0
HKD2_k127_5437915_1 3-Beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 529.0
HKD2_k127_5437915_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000000000000000001785 210.0
HKD2_k127_5486208_0 histidine kinase HAMP region domain protein K03406 - - 4.75e-283 881.0
HKD2_k127_5486208_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 5.558e-207 658.0
HKD2_k127_5486208_10 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001401 280.0
HKD2_k127_5486208_11 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000466 270.0
HKD2_k127_5486208_12 DNA-binding transcription factor activity K06075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000568 240.0
HKD2_k127_5486208_13 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001117 226.0
HKD2_k127_5486208_15 Outer membrane protein beta-barrel domain K07275 - - 0.0000000000000000000000000000000000000000000000000000000000001202 218.0
HKD2_k127_5486208_16 - - - - 0.000000000000000000000000000000000000000000000000000000000001471 215.0
HKD2_k127_5486208_17 PFAM CYTH domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000004117 205.0
HKD2_k127_5486208_18 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000007177 178.0
HKD2_k127_5486208_19 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000166 173.0
HKD2_k127_5486208_2 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 619.0
HKD2_k127_5486208_20 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000000000006295 130.0
HKD2_k127_5486208_23 nuclease activity K06218 - - 0.00000000000000000001024 94.0
HKD2_k127_5486208_24 fibronectin type III domain protein - - - 0.000000001481 60.0
HKD2_k127_5486208_25 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.00000004088 55.0
HKD2_k127_5486208_26 alpha/beta hydrolase fold - - - 0.0001011 44.0
HKD2_k127_5486208_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 595.0
HKD2_k127_5486208_4 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 567.0
HKD2_k127_5486208_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 538.0
HKD2_k127_5486208_6 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 540.0
HKD2_k127_5486208_7 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 537.0
HKD2_k127_5486208_8 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 434.0
HKD2_k127_5486208_9 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 313.0
HKD2_k127_5494720_0 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000006487 234.0
HKD2_k127_5494720_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000001187 207.0
HKD2_k127_5502156_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 284.0
HKD2_k127_5502156_1 - - - - 0.000000000000000000000000000000000000000000000004807 172.0
HKD2_k127_5502156_2 - - - - 0.000000000000000000000000004201 109.0
HKD2_k127_5527605_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1369.0
HKD2_k127_5527605_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1052.0
HKD2_k127_5527605_10 PFAM peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 337.0
HKD2_k127_5527605_11 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 306.0
HKD2_k127_5527605_12 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004286 289.0
HKD2_k127_5527605_13 CHAD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004591 254.0
HKD2_k127_5527605_14 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000007073 227.0
HKD2_k127_5527605_15 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000004072 201.0
HKD2_k127_5527605_16 Peptidase C10 family - - - 0.000000000000000000000000000000000000000000000000000001657 222.0
HKD2_k127_5527605_17 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000006514 133.0
HKD2_k127_5527605_18 - - - - 0.000000000000000000000000000000001338 146.0
HKD2_k127_5527605_19 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000002045 134.0
HKD2_k127_5527605_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 5.53e-322 995.0
HKD2_k127_5527605_20 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000001558 121.0
HKD2_k127_5527605_21 Peptidase family M28 K19702 - 3.4.11.24 0.0000000000000000000000006912 124.0
HKD2_k127_5527605_22 PFAM SMP-30 Gluconolaconase K01219 - 3.2.1.81 0.000000000000004203 91.0
HKD2_k127_5527605_23 domain protein K20276 - - 0.00000000000002875 89.0
HKD2_k127_5527605_26 PhoD-like phosphatase K14274,K14645,K20276 - - 0.00000000294 72.0
HKD2_k127_5527605_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.713e-320 983.0
HKD2_k127_5527605_4 histidine kinase HAMP region domain protein - - - 1.573e-219 713.0
HKD2_k127_5527605_5 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 571.0
HKD2_k127_5527605_6 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 525.0
HKD2_k127_5527605_7 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 469.0
HKD2_k127_5527605_8 YicC domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 440.0
HKD2_k127_5527605_9 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 369.0
HKD2_k127_5538184_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 394.0
HKD2_k127_5538184_1 Bacterial SH3 domain homologues - - - 0.000000000000000000000000000000000000000000000000000001417 194.0
HKD2_k127_55937_0 Na+/Pi-cotransporter K03324 - - 2.681e-244 766.0
HKD2_k127_55937_1 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 542.0
HKD2_k127_55937_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 429.0
HKD2_k127_55937_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000009151 225.0
HKD2_k127_55937_4 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000000000000000000000043 170.0
HKD2_k127_55937_5 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000001083 158.0
HKD2_k127_5615956_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 382.0
HKD2_k127_5627550_0 - - - - 0.00000000000000005619 92.0
HKD2_k127_5640021_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1755.0
HKD2_k127_5640021_1 Sensor histidine kinase, HAMP and PAS domain-containing - - - 0.0 1049.0
HKD2_k127_5640021_10 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 351.0
HKD2_k127_5640021_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 338.0
HKD2_k127_5640021_12 YaeQ - - - 0.00000000000000000000000005958 108.0
HKD2_k127_5640021_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.86e-293 902.0
HKD2_k127_5640021_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.663e-272 839.0
HKD2_k127_5640021_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 5.708e-227 709.0
HKD2_k127_5640021_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 590.0
HKD2_k127_5640021_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 528.0
HKD2_k127_5640021_7 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 430.0
HKD2_k127_5640021_8 PFAM MscS Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 407.0
HKD2_k127_5640021_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 351.0
HKD2_k127_5640380_0 reverse transcriptase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 601.0
HKD2_k127_5642809_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1172.0
HKD2_k127_5642809_1 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 398.0
HKD2_k127_5642809_2 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000002326 139.0
HKD2_k127_5642809_3 Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000005964 129.0
HKD2_k127_5699851_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1548.0
HKD2_k127_5699851_1 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1522.0
HKD2_k127_5699851_10 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000002265 171.0
HKD2_k127_5699851_11 chromate transporter K07240 - - 0.00000000000000000000000000000007464 132.0
HKD2_k127_5699851_12 Polymorphic membrane protein, Chlamydia - - - 0.000000000000000000000009581 120.0
HKD2_k127_5699851_13 pyridoxamine 5-phosphate oxidase-related K07005 - - 0.00004269 48.0
HKD2_k127_5699851_2 Cytochrome c bacterial - - - 5.058e-238 742.0
HKD2_k127_5699851_3 Belongs to the peptidase S8 family K08651 - 3.4.21.66 2.22e-201 695.0
HKD2_k127_5699851_4 cheY-homologous receiver domain K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 581.0
HKD2_k127_5699851_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 518.0
HKD2_k127_5699851_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 509.0
HKD2_k127_5699851_7 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 374.0
HKD2_k127_5699851_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 315.0
HKD2_k127_5699851_9 Transcriptional regulator K18136 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000001556 218.0
HKD2_k127_5703889_0 sptr a7nhu5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 401.0
HKD2_k127_5703889_1 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 346.0
HKD2_k127_5703889_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.00000008402 61.0
HKD2_k127_5703889_3 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.000000784 53.0
HKD2_k127_5716782_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000431 163.0
HKD2_k127_5716782_1 Putative Ig domain - - - 0.00000000000001851 86.0
HKD2_k127_5724091_0 Elongator protein 3, MiaB family, Radical SAM - - - 7.781e-281 864.0
HKD2_k127_5724091_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.479e-242 757.0
HKD2_k127_5724091_10 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.00000000000000001558 93.0
HKD2_k127_5724091_11 - - - - 0.0000000002362 70.0
HKD2_k127_5724091_2 MFS/sugar transport protein - - - 1.726e-195 616.0
HKD2_k127_5724091_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 556.0
HKD2_k127_5724091_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 514.0
HKD2_k127_5724091_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 401.0
HKD2_k127_5724091_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K01829,K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000001431 196.0
HKD2_k127_5724091_9 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000000000000006361 145.0
HKD2_k127_5736711_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1608.0
HKD2_k127_5736711_1 - - - - 6.9e-252 801.0
HKD2_k127_5736711_10 Cytochrome c3 - - - 3.041e-195 612.0
HKD2_k127_5736711_11 conserved protein UCP016719 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 590.0
HKD2_k127_5736711_12 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 574.0
HKD2_k127_5736711_13 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 495.0
HKD2_k127_5736711_14 Acetokinase family K00929 - 2.7.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 496.0
HKD2_k127_5736711_15 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 491.0
HKD2_k127_5736711_16 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 476.0
HKD2_k127_5736711_17 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 475.0
HKD2_k127_5736711_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 466.0
HKD2_k127_5736711_19 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 446.0
HKD2_k127_5736711_2 PAS domain containing protein - - - 9.563e-249 781.0
HKD2_k127_5736711_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 427.0
HKD2_k127_5736711_21 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 421.0
HKD2_k127_5736711_22 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 394.0
HKD2_k127_5736711_23 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 391.0
HKD2_k127_5736711_24 cog0421, spermidine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 378.0
HKD2_k127_5736711_25 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 357.0
HKD2_k127_5736711_26 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 339.0
HKD2_k127_5736711_27 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 300.0
HKD2_k127_5736711_28 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 295.0
HKD2_k127_5736711_29 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 296.0
HKD2_k127_5736711_3 PFAM Rh family protein ammonium transporter K03320 - - 1.239e-241 749.0
HKD2_k127_5736711_30 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 282.0
HKD2_k127_5736711_33 CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000008623 216.0
HKD2_k127_5736711_34 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000009848 197.0
HKD2_k127_5736711_37 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000001494 145.0
HKD2_k127_5736711_38 response regulator K02282,K07782,K19135 - - 0.00000000000000000000000000000000000004577 149.0
HKD2_k127_5736711_39 - - - - 0.00000000000000000000000000000007968 125.0
HKD2_k127_5736711_4 POTRA domain TamA domain 1 K07277,K07278 - - 2.059e-238 750.0
HKD2_k127_5736711_5 Histone deacetylase domain K04768 - - 1.563e-225 702.0
HKD2_k127_5736711_6 Phosphate acetyl/butaryl transferase K00634 - 2.3.1.19 5.886e-224 705.0
HKD2_k127_5736711_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 3.144e-216 677.0
HKD2_k127_5736711_8 Serine aminopeptidase, S33 K03928 - 3.1.1.1 5.096e-215 690.0
HKD2_k127_5736711_9 TonB dependent receptor K02014 - - 7.706e-196 631.0
HKD2_k127_5738225_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1219.0
HKD2_k127_5738225_1 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 2.466e-205 643.0
HKD2_k127_5738225_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 567.0
HKD2_k127_5738225_3 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000000000000009394 200.0
HKD2_k127_5740912_0 Phage tail tape measure protein TP901 - - - 0.00000000000003306 78.0
HKD2_k127_5740912_1 - - - - 0.0001518 52.0
HKD2_k127_5791606_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 350.0
HKD2_k127_5791606_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000007899 141.0
HKD2_k127_5803318_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1825.0
HKD2_k127_5803318_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 6.244e-224 702.0
HKD2_k127_5803318_10 Sugar efflux transporter for intercellular exchange - - - 0.00000000000000000000000000000000000000000001911 165.0
HKD2_k127_5803318_2 sulphate transporter - - - 8.362e-195 623.0
HKD2_k127_5803318_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 572.0
HKD2_k127_5803318_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 560.0
HKD2_k127_5803318_5 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 546.0
HKD2_k127_5803318_6 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 458.0
HKD2_k127_5803318_7 lipid catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 394.0
HKD2_k127_5803318_8 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001523 284.0
HKD2_k127_5803318_9 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000001921 214.0
HKD2_k127_583705_0 COG3209 Rhs family protein - - - 0.0 1679.0
HKD2_k127_583705_1 Baseplate J-like protein - - - 0.0 1515.0
HKD2_k127_583705_10 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000000000000000000000000000000000000001501 228.0
HKD2_k127_583705_11 GGDEF domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000819 213.0
HKD2_k127_583705_12 - - - - 0.000000000000000000000000000000000000000000000000000000000111 211.0
HKD2_k127_583705_13 - - - - 0.000000000000000000000000000000000000000000000000001064 188.0
HKD2_k127_583705_14 PAAR motif - - - 0.00000000000000000000000000000000000005287 145.0
HKD2_k127_583705_15 - - - - 0.0000000006747 63.0
HKD2_k127_583705_2 protein of Photorhabdus and some similarities with - - - 0.0 1319.0
HKD2_k127_583705_3 Domain of unknown function (DUF4157) - - - 0.0 1206.0
HKD2_k127_583705_4 Phage late control gene D protein (GPD) - - - 1.768e-280 882.0
HKD2_k127_583705_5 PFAM AAA ATPase central domain protein - - - 1.223e-199 630.0
HKD2_k127_583705_6 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 368.0
HKD2_k127_583705_7 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 356.0
HKD2_k127_583705_8 T4-like virus tail tube protein gp19 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007156 273.0
HKD2_k127_583705_9 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005429 262.0
HKD2_k127_58373_0 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 1.061e-287 888.0
HKD2_k127_58373_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 595.0
HKD2_k127_58373_2 N-terminal domain of unknown function (DUF4140) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 374.0
HKD2_k127_58373_3 - - - - 0.00000000000000004045 84.0
HKD2_k127_5865821_0 amino acid-binding ACT domain protein K00003 - 1.1.1.3 6.675e-249 773.0
HKD2_k127_5865821_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 4.645e-244 755.0
HKD2_k127_5865821_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 581.0
HKD2_k127_5865821_3 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 378.0
HKD2_k127_5865821_4 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 313.0
HKD2_k127_5865821_5 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 301.0
HKD2_k127_5865821_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 289.0
HKD2_k127_5865821_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 282.0
HKD2_k127_5865821_8 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006382 256.0
HKD2_k127_5865821_9 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0000000000000000000000000002804 113.0
HKD2_k127_5868758_0 Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000004217 150.0
HKD2_k127_5871540_0 Beta-eliminating lyase K04487 - 2.8.1.7 1.119e-195 619.0
HKD2_k127_5871540_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 574.0
HKD2_k127_5871540_2 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 539.0
HKD2_k127_5871540_3 SMART Elongator protein 3 MiaB NifB K02585 - - 0.00000000000000000000000000000000000002331 145.0
HKD2_k127_5890243_0 type I restriction modification DNA specificity domain - - - 0.000000000000000000000000000000000000000000001791 169.0
HKD2_k127_5907327_0 COG3335 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005941 285.0
HKD2_k127_5907327_1 SPTR B0JN73 Transposase - - - 0.00000000005147 65.0
HKD2_k127_5998921_0 Extradiol ring-cleavage dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 377.0
HKD2_k127_5998921_1 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 308.0
HKD2_k127_5998921_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001711 248.0
HKD2_k127_5998921_3 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004236 246.0
HKD2_k127_5998921_4 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.000000000000000000000000000000000000000000000000000002219 196.0
HKD2_k127_5998921_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000005379 148.0
HKD2_k127_5998921_6 Domain of unknown function (DUF1904) - - - 0.0000000000000000000000000000584 119.0
HKD2_k127_605535_0 PFAM Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 435.0
HKD2_k127_605535_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000004403 155.0
HKD2_k127_6071170_0 PFAM Rhodopirellula transposase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 324.0
HKD2_k127_6071170_1 PFAM Rhodopirellula transposase family protein - - - 0.000000000000000000000000000000000001017 145.0
HKD2_k127_6071170_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000000001454 68.0
HKD2_k127_6086697_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0 1188.0
HKD2_k127_6086697_1 Iron-sulfur cluster-binding domain - - - 5.131e-254 788.0
HKD2_k127_6086697_2 Major facilitator superfamily MFS_1 - - - 4.46e-220 687.0
HKD2_k127_6086697_3 B12 binding domain - - - 6.445e-212 662.0
HKD2_k127_6086697_4 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 398.0
HKD2_k127_6086697_5 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 377.0
HKD2_k127_6086697_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
HKD2_k127_6086697_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003475 255.0
HKD2_k127_6086697_8 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000000000000000716 134.0
HKD2_k127_6156821_0 PFAM Transposase, IS4-like - - - 0.0000000000000000000000000000000000000000000006195 169.0
HKD2_k127_6156821_1 transposase activity - - - 0.000000000000000000000000000000000000001077 162.0
HKD2_k127_6156821_2 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000000004894 91.0
HKD2_k127_6156821_3 Transposase - - - 0.0001172 44.0
HKD2_k127_618674_0 - - - - 0.0009954 50.0
HKD2_k127_6200152_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1208.0
HKD2_k127_6200152_1 Protein of unknown function (DUF2442) - - - 0.0000002 52.0
HKD2_k127_62388_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.379e-267 824.0
HKD2_k127_62388_1 Tfp pilus assembly protein FimV - - - 6.094e-227 712.0
HKD2_k127_62388_10 Transposase IS200 like - - - 0.000000000000000000000000000000000000003412 158.0
HKD2_k127_62388_11 Nucleotidyltransferase domain - - - 0.000000000000000000000000000000000001295 140.0
HKD2_k127_62388_12 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000000001412 138.0
HKD2_k127_62388_14 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000001017 64.0
HKD2_k127_62388_2 Possible lysine decarboxylase K06966 - 3.2.2.10 4.703e-199 623.0
HKD2_k127_62388_3 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 575.0
HKD2_k127_62388_4 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 559.0
HKD2_k127_62388_5 Pfam:DUF422 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 484.0
HKD2_k127_62388_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 455.0
HKD2_k127_62388_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 316.0
HKD2_k127_62388_8 Nucleotidyltransferase substrate binding protein like - - - 0.000000000000000000000000000000000000000000000000001857 190.0
HKD2_k127_62388_9 Cytochrome P460 - - - 0.0000000000000000000000000000000000000003258 152.0
HKD2_k127_6275178_0 glutamate synthase, alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2173.0
HKD2_k127_6275178_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1278.0
HKD2_k127_6275178_10 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 576.0
HKD2_k127_6275178_11 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 573.0
HKD2_k127_6275178_12 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 509.0
HKD2_k127_6275178_13 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 506.0
HKD2_k127_6275178_14 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 494.0
HKD2_k127_6275178_15 Sensory domain found in PocR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 500.0
HKD2_k127_6275178_16 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 464.0
HKD2_k127_6275178_17 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 445.0
HKD2_k127_6275178_18 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 426.0
HKD2_k127_6275178_19 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 412.0
HKD2_k127_6275178_2 Histidine kinase - - - 0.0 1050.0
HKD2_k127_6275178_20 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 394.0
HKD2_k127_6275178_21 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 374.0
HKD2_k127_6275178_22 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 332.0
HKD2_k127_6275178_23 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 337.0
HKD2_k127_6275178_24 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 327.0
HKD2_k127_6275178_25 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 310.0
HKD2_k127_6275178_26 PFAM phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 315.0
HKD2_k127_6275178_27 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 312.0
HKD2_k127_6275178_28 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 303.0
HKD2_k127_6275178_29 Sporulation and spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
HKD2_k127_6275178_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0 1024.0
HKD2_k127_6275178_30 Acyl carrier protein phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001375 275.0
HKD2_k127_6275178_31 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000001562 231.0
HKD2_k127_6275178_32 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000000001238 181.0
HKD2_k127_6275178_33 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000000006166 163.0
HKD2_k127_6275178_34 PFAM Membrane protein of K08972 - - 0.000000000000000000000000000000000000001152 151.0
HKD2_k127_6275178_35 GYD domain - - - 0.00000000000000000000000000000000002466 137.0
HKD2_k127_6275178_36 phosphorelay signal transduction system K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000001855 107.0
HKD2_k127_6275178_38 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000002875 86.0
HKD2_k127_6275178_39 PFAM SpoVT AbrB K07172,K18842 - - 0.000000000000000151 82.0
HKD2_k127_6275178_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.931e-256 792.0
HKD2_k127_6275178_5 Aldehyde dehydrogenase family K22187 - - 2.335e-217 684.0
HKD2_k127_6275178_6 MacB-like periplasmic core domain K02004 - - 6.454e-216 676.0
HKD2_k127_6275178_7 PFAM outer membrane efflux protein - - - 1.59e-196 636.0
HKD2_k127_6275178_8 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 580.0
HKD2_k127_6275178_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 579.0
HKD2_k127_6312488_0 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0 3493.0
HKD2_k127_6312488_1 Fibronectin type 3 domain K20276 - - 0.0 3132.0
HKD2_k127_6312488_2 domain protein - - - 1.064e-257 806.0
HKD2_k127_6312488_3 SMART Elongator protein 3 MiaB NifB - - - 6.097e-240 745.0
HKD2_k127_6312488_4 cytochrome c biogenesis protein K07399 - - 7.738e-196 624.0
HKD2_k127_6312488_5 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 490.0
HKD2_k127_6312488_6 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 377.0
HKD2_k127_6383701_0 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 514.0
HKD2_k127_6383701_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000257 224.0
HKD2_k127_6383701_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000007557 204.0
HKD2_k127_6388033_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1500.0
HKD2_k127_6388033_1 Domains FehydlgC, FeS, sigma54 interaction, HTH8 - - - 0.0 1384.0
HKD2_k127_6388033_10 Chemotaxis sensory transducer K03406 - - 9.67e-239 760.0
HKD2_k127_6388033_11 histidine kinase, HAMP - - - 4.144e-236 737.0
HKD2_k127_6388033_12 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 3.694e-224 702.0
HKD2_k127_6388033_13 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 1.657e-210 664.0
HKD2_k127_6388033_14 flagellar motor switch protein FliG K02410 - - 7.968e-194 606.0
HKD2_k127_6388033_15 Ion transport 2 domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 598.0
HKD2_k127_6388033_16 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 609.0
HKD2_k127_6388033_17 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 581.0
HKD2_k127_6388033_18 flagellar motor switch protein FliM K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 565.0
HKD2_k127_6388033_19 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 574.0
HKD2_k127_6388033_2 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.0 1034.0
HKD2_k127_6388033_20 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 557.0
HKD2_k127_6388033_21 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 514.0
HKD2_k127_6388033_22 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 491.0
HKD2_k127_6388033_23 GGDEF domain K01768,K02482,K02658,K03413,K07315 - 2.7.13.3,3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 487.0
HKD2_k127_6388033_24 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 466.0
HKD2_k127_6388033_25 beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 460.0
HKD2_k127_6388033_26 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 466.0
HKD2_k127_6388033_27 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 433.0
HKD2_k127_6388033_28 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
HKD2_k127_6388033_29 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 402.0
HKD2_k127_6388033_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.345e-279 864.0
HKD2_k127_6388033_30 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 419.0
HKD2_k127_6388033_31 flagellar biosynthetic protein FliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 381.0
HKD2_k127_6388033_32 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 375.0
HKD2_k127_6388033_33 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006038 377.0
HKD2_k127_6388033_34 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
HKD2_k127_6388033_35 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 361.0
HKD2_k127_6388033_36 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 372.0
HKD2_k127_6388033_37 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 355.0
HKD2_k127_6388033_38 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 362.0
HKD2_k127_6388033_39 Flagellar basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 349.0
HKD2_k127_6388033_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 2.835e-272 842.0
HKD2_k127_6388033_40 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
HKD2_k127_6388033_41 alpha-ribazole phosphatase activity K02226,K22305,K22306 - 3.1.3.3,3.1.3.73,3.1.3.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 325.0
HKD2_k127_6388033_42 Chemotaxis phosphatase CheX K03409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 301.0
HKD2_k127_6388033_43 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 287.0
HKD2_k127_6388033_44 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001064 271.0
HKD2_k127_6388033_45 Domains REC, HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004096 287.0
HKD2_k127_6388033_46 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000138 254.0
HKD2_k127_6388033_47 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000002135 267.0
HKD2_k127_6388033_48 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008861 241.0
HKD2_k127_6388033_49 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
HKD2_k127_6388033_5 Thiamine biosynthesis protein ThiC K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 1.608e-268 829.0
HKD2_k127_6388033_50 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000004241 226.0
HKD2_k127_6388033_51 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000000000000000009908 213.0
HKD2_k127_6388033_52 bacterial-type flagellum organization K02413 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
HKD2_k127_6388033_53 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000003467 214.0
HKD2_k127_6388033_54 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000000000000001719 202.0
HKD2_k127_6388033_55 Putative flagellar - - - 0.000000000000000000000000000000000000000000000000000000002025 201.0
HKD2_k127_6388033_56 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000000000000000000008186 204.0
HKD2_k127_6388033_57 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000001529 217.0
HKD2_k127_6388033_58 flagellar K02418 - - 0.00000000000000000000000000000000000000000000000000000005647 203.0
HKD2_k127_6388033_59 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
HKD2_k127_6388033_6 The M ring may be actively involved in energy transduction K02409 - - 1.073e-264 822.0
HKD2_k127_6388033_60 PFAM flagellar hook-length control K02414 - - 0.0000000000000000000000000000000000000000000000000000001129 219.0
HKD2_k127_6388033_61 PFAM MgtE intracellular - - - 0.000000000000000000000000000000000000000000000000001298 190.0
HKD2_k127_6388033_62 Flagellar motor switch protein FliN K02417 - - 0.000000000000000000000000000000000000000000000000005065 181.0
HKD2_k127_6388033_63 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000002662 182.0
HKD2_k127_6388033_64 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000002008 170.0
HKD2_k127_6388033_65 Flagellar biosynthetic protein FliQ K02420 - - 0.00000000000000000000000000000000000000000006227 160.0
HKD2_k127_6388033_66 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000000000000002759 140.0
HKD2_k127_6388033_67 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000000001018 142.0
HKD2_k127_6388033_69 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000001088 102.0
HKD2_k127_6388033_7 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412,K03224 - 3.6.3.14 1.84e-257 797.0
HKD2_k127_6388033_70 - K02009 - - 0.0000000000000000308 84.0
HKD2_k127_6388033_71 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000002762 79.0
HKD2_k127_6388033_73 Flagellar assembly protein FliH K02411 - - 0.00000003027 64.0
HKD2_k127_6388033_74 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000005072 57.0
HKD2_k127_6388033_8 protein trimerization K06894,K07114 - - 1.888e-256 809.0
HKD2_k127_6388033_9 response regulator - - - 1.154e-253 788.0
HKD2_k127_6398236_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1735.0
HKD2_k127_6398236_1 malic protein domain protein K00029 - 1.1.1.40 0.0 1313.0
HKD2_k127_6398236_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 574.0
HKD2_k127_6398236_11 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 551.0
HKD2_k127_6398236_12 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 536.0
HKD2_k127_6398236_13 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 529.0
HKD2_k127_6398236_14 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 461.0
HKD2_k127_6398236_15 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 433.0
HKD2_k127_6398236_16 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 459.0
HKD2_k127_6398236_17 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 430.0
HKD2_k127_6398236_18 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 396.0
HKD2_k127_6398236_19 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 394.0
HKD2_k127_6398236_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1238.0
HKD2_k127_6398236_20 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 383.0
HKD2_k127_6398236_21 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 370.0
HKD2_k127_6398236_22 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 357.0
HKD2_k127_6398236_23 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 315.0
HKD2_k127_6398236_24 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 301.0
HKD2_k127_6398236_25 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 281.0
HKD2_k127_6398236_26 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000001337 241.0
HKD2_k127_6398236_27 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000003976 242.0
HKD2_k127_6398236_28 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000000000000000000000000000000000000000000000000000005429 238.0
HKD2_k127_6398236_29 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000001426 229.0
HKD2_k127_6398236_3 Domain of unknown function (DUF3488) - - - 2.022e-237 749.0
HKD2_k127_6398236_30 PFAM outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000001117 211.0
HKD2_k127_6398236_31 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000009118 193.0
HKD2_k127_6398236_32 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000001996 198.0
HKD2_k127_6398236_33 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000005622 170.0
HKD2_k127_6398236_34 - - - - 0.000000000000000000000000000000000000000000002055 171.0
HKD2_k127_6398236_4 PFAM peptidase M16 domain protein - - - 2.642e-227 708.0
HKD2_k127_6398236_5 PFAM peptidase M29, aminopeptidase II K19689 - - 7.025e-224 696.0
HKD2_k127_6398236_6 - - - - 1.141e-209 659.0
HKD2_k127_6398236_7 acyl-coa dehydrogenase K00248 - 1.3.8.1 4.257e-200 629.0
HKD2_k127_6398236_8 Biotin-lipoyl like K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 611.0
HKD2_k127_6398236_9 TOBE domain K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 578.0
HKD2_k127_6398533_0 Pkd domain containing protein - - - 0.0000003758 62.0
HKD2_k127_6420255_0 SMART Elongator protein 3 MiaB NifB K22227 - - 3.056e-234 728.0
HKD2_k127_6420255_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 8.425e-218 679.0
HKD2_k127_6420255_10 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000008903 222.0
HKD2_k127_6420255_11 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000009065 189.0
HKD2_k127_6420255_12 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000002385 182.0
HKD2_k127_6420255_13 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000004299 164.0
HKD2_k127_6420255_14 - - - - 0.0000000000000000000000000000000000000000004877 160.0
HKD2_k127_6420255_15 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000000003896 158.0
HKD2_k127_6420255_16 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000000000002136 130.0
HKD2_k127_6420255_17 - - - - 0.000000000000000000000000000006516 120.0
HKD2_k127_6420255_18 PFAM Pyridoxamine 5'-phosphate oxidase-related K07005 - - 0.000000000000000000000000001391 120.0
HKD2_k127_6420255_2 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 574.0
HKD2_k127_6420255_20 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000001351 106.0
HKD2_k127_6420255_22 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000000000002765 97.0
HKD2_k127_6420255_23 response regulator, receiver K03413 - - 0.00000000000000001751 87.0
HKD2_k127_6420255_24 Neprosin - - - 0.00000000000155 69.0
HKD2_k127_6420255_25 Prolyl oligopeptidase family - - - 0.0000000008535 70.0
HKD2_k127_6420255_27 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000006529 59.0
HKD2_k127_6420255_28 Cysteine-rich domain - - - 0.0002645 47.0
HKD2_k127_6420255_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 533.0
HKD2_k127_6420255_4 2 heme-binding sites K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 527.0
HKD2_k127_6420255_5 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 451.0
HKD2_k127_6420255_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 347.0
HKD2_k127_6420255_7 Flagellar Assembly Protein A K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 325.0
HKD2_k127_6420255_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001671 261.0
HKD2_k127_6420255_9 Protein of unknown function (DUF1456) - - - 0.00000000000000000000000000000000000000000000000000000000000000003639 228.0
HKD2_k127_6424263_0 Glycosyl transferase family 2 - - - 0.0 2005.0
HKD2_k127_6424263_1 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0 1887.0
HKD2_k127_6424263_10 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.017e-268 840.0
HKD2_k127_6424263_11 Sensor histidine kinase, PAS and GAF domain-containing - - - 2.4e-267 838.0
HKD2_k127_6424263_12 glycosyl transferase - - - 4.643e-263 829.0
HKD2_k127_6424263_13 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.582e-255 789.0
HKD2_k127_6424263_14 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 1.152e-232 722.0
HKD2_k127_6424263_15 repeat-containing protein - - - 1.881e-228 724.0
HKD2_k127_6424263_16 PFAM type II secretion system protein E K02669 - - 2.457e-216 674.0
HKD2_k127_6424263_18 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 3.198e-205 642.0
HKD2_k127_6424263_19 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.473e-198 620.0
HKD2_k127_6424263_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1701.0
HKD2_k127_6424263_20 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 608.0
HKD2_k127_6424263_21 transferase activity, transferring glycosyl groups K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 593.0
HKD2_k127_6424263_22 glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 584.0
HKD2_k127_6424263_23 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 557.0
HKD2_k127_6424263_24 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 565.0
HKD2_k127_6424263_25 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 541.0
HKD2_k127_6424263_26 Motility response receiver histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 538.0
HKD2_k127_6424263_27 Macrocin-O-methyltransferase (TylF) K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 491.0
HKD2_k127_6424263_28 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 440.0
HKD2_k127_6424263_29 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 459.0
HKD2_k127_6424263_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1675.0
HKD2_k127_6424263_30 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 443.0
HKD2_k127_6424263_31 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 322.0
HKD2_k127_6424263_32 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 299.0
HKD2_k127_6424263_33 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000237 305.0
HKD2_k127_6424263_34 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005767 265.0
HKD2_k127_6424263_35 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000009612 256.0
HKD2_k127_6424263_36 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000001859 244.0
HKD2_k127_6424263_37 PFAM flagellar FlaF family protein K06602 - - 0.000000000000000000000000000000000000000000000000000000000000000000003081 235.0
HKD2_k127_6424263_38 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000000000000000000000000000002418 198.0
HKD2_k127_6424263_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1557.0
HKD2_k127_6424263_40 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000000000006991 196.0
HKD2_k127_6424263_41 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000000000000003599 183.0
HKD2_k127_6424263_42 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000469 162.0
HKD2_k127_6424263_43 PFAM flagellar FlbT family protein K06601 - - 0.0000000000000000000000000000000001355 136.0
HKD2_k127_6424263_44 DNA polymerase beta domain protein region K07075 - - 0.000000000000000000000000000006972 121.0
HKD2_k127_6424263_45 Glycosyl transferases group 1 - - - 0.00004851 46.0
HKD2_k127_6424263_5 repeat-containing protein - - - 0.0 1347.0
HKD2_k127_6424263_6 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0 1200.0
HKD2_k127_6424263_7 Transport of potassium into the cell K03549 - - 1.925e-319 985.0
HKD2_k127_6424263_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 3.556e-287 886.0
HKD2_k127_6424263_9 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.061e-274 848.0
HKD2_k127_6425212_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1246.0
HKD2_k127_6425212_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 426.0
HKD2_k127_6425212_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 408.0
HKD2_k127_6425212_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 358.0
HKD2_k127_6425212_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 290.0
HKD2_k127_6425212_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 273.0
HKD2_k127_6425212_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000000000000003732 218.0
HKD2_k127_6425212_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000006812 107.0
HKD2_k127_6425212_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000002209 105.0
HKD2_k127_6426709_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 4.013e-224 698.0
HKD2_k127_6426709_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000087 209.0
HKD2_k127_6426709_4 ABC transporter K06158 - - 0.00000000000000007088 79.0
HKD2_k127_6428450_0 PFAM Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 524.0
HKD2_k127_6428450_1 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 329.0
HKD2_k127_6428450_2 PFAM transposase IS4 family protein K07487 - - 0.00000000000005115 79.0
HKD2_k127_6431005_0 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.0 1043.0
HKD2_k127_6431005_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.877e-291 898.0
HKD2_k127_6431005_10 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 342.0
HKD2_k127_6431005_11 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 280.0
HKD2_k127_6431005_12 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001727 278.0
HKD2_k127_6431005_13 Protein of unknown function (DUF1318) K09978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001198 280.0
HKD2_k127_6431005_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000000000003203 198.0
HKD2_k127_6431005_15 anaphase-promoting complex-dependent catabolic process - - - 0.0000000000000000000000000000000000000000000000000008563 189.0
HKD2_k127_6431005_16 phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000008659 157.0
HKD2_k127_6431005_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 1.239e-238 741.0
HKD2_k127_6431005_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 4.766e-198 621.0
HKD2_k127_6431005_4 Pyridine nucleotide-disulphide oxidoreductase K00383 - 1.8.1.7 2.987e-194 614.0
HKD2_k127_6431005_5 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 578.0
HKD2_k127_6431005_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 453.0
HKD2_k127_6431005_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 371.0
HKD2_k127_6431005_8 Pfam:DUF162 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 370.0
HKD2_k127_6431005_9 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 357.0
HKD2_k127_6433003_0 GTP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 367.0
HKD2_k127_6433003_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000004472 229.0
HKD2_k127_6433003_2 Putative transposase of IS4/5 family (DUF4096) - - - 0.0000000000000000000000000000001002 127.0
HKD2_k127_6442546_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 9.398e-237 737.0
HKD2_k127_6442546_1 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 507.0
HKD2_k127_6442546_2 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 293.0
HKD2_k127_6442546_3 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000003145 235.0
HKD2_k127_6442546_4 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000001424 145.0
HKD2_k127_6442546_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.00000000000002822 74.0
HKD2_k127_6443173_0 transposition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 543.0
HKD2_k127_6443173_2 transposition - - - 0.000000000000001437 80.0
HKD2_k127_6443389_0 Amidohydrolase family K06015 - 3.5.1.81 1.989e-204 650.0
HKD2_k127_6443389_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00004754 45.0
HKD2_k127_6464812_0 Seven times multi-haem cytochrome CxxCH - - - 2.411e-231 721.0
HKD2_k127_6464812_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 314.0
HKD2_k127_6464812_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000007535 68.0
HKD2_k127_6464812_4 Protein conserved in bacteria K09764 - - 0.000000001856 61.0
HKD2_k127_6465797_0 domain, Protein K15125,K20276 - - 0.00000000000000000000000000000000003297 158.0
HKD2_k127_6465797_1 axonogenesis involved in innervation - GO:0000902,GO:0000904,GO:0001678,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005886,GO:0006810,GO:0006839,GO:0006915,GO:0006996,GO:0007005,GO:0007154,GO:0007267,GO:0007268,GO:0007275,GO:0007399,GO:0007409,GO:0007417,GO:0008150,GO:0008219,GO:0008637,GO:0009653,GO:0009743,GO:0009746,GO:0009749,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0012501,GO:0016020,GO:0016043,GO:0019725,GO:0021675,GO:0022008,GO:0023052,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0033500,GO:0034284,GO:0035864,GO:0035865,GO:0042221,GO:0042592,GO:0042593,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043653,GO:0044424,GO:0044444,GO:0044464,GO:0048468,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055082,GO:0060384,GO:0060385,GO:0061564,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071310,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071840,GO:0071944,GO:0097458,GO:0098916,GO:0099536,GO:0099537,GO:0120025,GO:0120036,GO:0120039,GO:1901700,GO:1901701 - 0.0000000000000000000000000002052 136.0
HKD2_k127_6465797_2 pyrroloquinoline quinone binding K01051 - 3.1.1.11 0.000000000000000000308 106.0
HKD2_k127_6465797_3 acid phosphatase activity - - - 0.0000001925 66.0
HKD2_k127_6466819_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.741e-261 808.0
HKD2_k127_6466819_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 436.0
HKD2_k127_6466819_2 SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 310.0
HKD2_k127_6466819_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 281.0
HKD2_k127_6466819_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000008122 225.0
HKD2_k127_6466819_5 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000004669 184.0
HKD2_k127_6466819_6 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000000001504 136.0
HKD2_k127_6466819_7 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000002945 96.0
HKD2_k127_6472355_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 297.0
HKD2_k127_6472355_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000001175 147.0
HKD2_k127_6472355_2 MULE transposase domain - - - 0.000000000000000000000000000000003165 139.0
HKD2_k127_6472355_3 Transposase - - - 0.000000000000000000165 95.0
HKD2_k127_6482231_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0 1375.0
HKD2_k127_6482231_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1212.0
HKD2_k127_6482231_10 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 338.0
HKD2_k127_6482231_11 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 331.0
HKD2_k127_6482231_12 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 318.0
HKD2_k127_6482231_13 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 317.0
HKD2_k127_6482231_14 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
HKD2_k127_6482231_15 phosphonoacetaldehyde hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 314.0
HKD2_k127_6482231_16 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000069 260.0
HKD2_k127_6482231_17 glycerophosphodiester phosphodiesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000005831 234.0
HKD2_k127_6482231_18 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000002117 235.0
HKD2_k127_6482231_19 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000005641 214.0
HKD2_k127_6482231_2 response regulator K02667 - - 3.144e-245 762.0
HKD2_k127_6482231_20 biosynthesis protein E K06139 - - 0.00000000000000000000000000000000000000000000000000000000000005828 227.0
HKD2_k127_6482231_21 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000008307 178.0
HKD2_k127_6482231_22 WavE lipopolysaccharide synthesis - - - 0.000000000000000000000000000000000000000000000000333 189.0
HKD2_k127_6482231_23 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000004188 179.0
HKD2_k127_6482231_24 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000005131 158.0
HKD2_k127_6482231_25 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000001046 150.0
HKD2_k127_6482231_26 - - - - 0.0000000000000000000000000000000000005125 144.0
HKD2_k127_6482231_27 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000000000008888 122.0
HKD2_k127_6482231_28 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000001553 134.0
HKD2_k127_6482231_29 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000004716 131.0
HKD2_k127_6482231_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 8.448e-201 627.0
HKD2_k127_6482231_30 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000008468 118.0
HKD2_k127_6482231_31 Methyltransferase domain - - - 0.000000000000000000001131 105.0
HKD2_k127_6482231_32 - - - - 0.00000000000000000005648 90.0
HKD2_k127_6482231_33 Sulfatase - - - 0.000000000000001234 78.0
HKD2_k127_6482231_34 - - - - 0.00000000007741 76.0
HKD2_k127_6482231_35 Glycosyltransferase like family 2 - - - 0.000000001627 71.0
HKD2_k127_6482231_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 583.0
HKD2_k127_6482231_5 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 462.0
HKD2_k127_6482231_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 388.0
HKD2_k127_6482231_7 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 375.0
HKD2_k127_6482231_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 360.0
HKD2_k127_6482231_9 ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 346.0
HKD2_k127_6482901_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 1.954e-303 935.0
HKD2_k127_6482901_1 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000004039 226.0
HKD2_k127_6482901_3 denitrification pathway - - - 0.0000000000006889 74.0
HKD2_k127_6483021_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 348.0
HKD2_k127_6483021_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044464,GO:0071944 2.1.1.163,2.1.1.201 0.000000000006141 74.0
HKD2_k127_6490567_0 Domain of Unknown Function (DUF748) - - - 8.259e-258 803.0
HKD2_k127_6490567_1 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 7.627e-218 685.0
HKD2_k127_6490567_10 - - - - 0.00000000000000000000000004622 109.0
HKD2_k127_6490567_2 Belongs to the ompA family K03286 - - 9.935e-195 617.0
HKD2_k127_6490567_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 559.0
HKD2_k127_6490567_4 radical SAM domain protein K18563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 540.0
HKD2_k127_6490567_5 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 515.0
HKD2_k127_6490567_6 Ku70/Ku80 beta-barrel domain K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 438.0
HKD2_k127_6490567_7 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 345.0
HKD2_k127_6490567_8 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 323.0
HKD2_k127_6490567_9 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
HKD2_k127_6504031_0 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0 1319.0
HKD2_k127_6504031_1 Domains REC, sigma54 interaction, HTH8 - - - 3.325e-277 855.0
HKD2_k127_6504031_10 general secretion pathway protein K10927 - - 0.000000000000000000000000000000000000007654 153.0
HKD2_k127_6504031_11 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 0.000000000000000001202 85.0
HKD2_k127_6504031_12 Sporulation and spore germination - - - 0.0000000001244 62.0
HKD2_k127_6504031_2 Histidine kinase HAMP - - - 1.573e-271 841.0
HKD2_k127_6504031_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 9.937e-216 673.0
HKD2_k127_6504031_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 560.0
HKD2_k127_6504031_5 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 531.0
HKD2_k127_6504031_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 415.0
HKD2_k127_6504031_7 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 387.0
HKD2_k127_6504031_8 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 344.0
HKD2_k127_6504031_9 - - - - 0.00000000000000000000000000000000000000000000000000005704 193.0
HKD2_k127_6506883_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 473.0
HKD2_k127_6506883_1 PFAM transposase, IS4 family protein - - - 0.0000000000000000000003621 96.0
HKD2_k127_6507004_0 transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 442.0
HKD2_k127_6507004_1 Zinc-binding domain of primase-helicase K06919 - - 0.00000000000000000000000000108 121.0
HKD2_k127_6507004_2 Transposase - - - 0.0000000000000001579 81.0
HKD2_k127_6507004_3 HTH-like domain K07497 - - 0.0003703 43.0
HKD2_k127_6508719_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1095.0
HKD2_k127_6508719_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 4.89e-225 704.0
HKD2_k127_6508719_2 amino acid-binding ACT domain protein K14170 - 4.2.1.51,5.4.99.5 7.245e-206 652.0
HKD2_k127_6508719_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 519.0
HKD2_k127_6508719_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 461.0
HKD2_k127_6508719_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 436.0
HKD2_k127_6508719_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 358.0
HKD2_k127_6508719_7 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 355.0
HKD2_k127_6508719_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000003459 179.0
HKD2_k127_6527474_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000001353 190.0
HKD2_k127_6532113_0 - - - - 3.326e-282 880.0
HKD2_k127_6532113_1 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000009372 180.0
HKD2_k127_6532113_2 DDE superfamily endonuclease K07494 - - 0.00000000000000000000000000158 114.0
HKD2_k127_6552674_0 Neisseria PilC beta-propeller domain K02674 - - 7.183e-235 768.0
HKD2_k127_6552674_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 1.241e-223 716.0
HKD2_k127_6552674_11 Prokaryotic N-terminal methylation motif - - - 0.0009411 50.0
HKD2_k127_6552674_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006242 395.0
HKD2_k127_6552674_3 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 336.0
HKD2_k127_6552674_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004231 254.0
HKD2_k127_6552674_5 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000001213 196.0
HKD2_k127_6552674_6 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000000923 128.0
HKD2_k127_655728_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 571.0
HKD2_k127_6572559_0 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1061.0
HKD2_k127_6572559_1 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 454.0
HKD2_k127_6572559_2 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 409.0
HKD2_k127_6572559_3 Smr protein MutS2 - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 292.0
HKD2_k127_6572559_4 PilZ domain - - - 0.000000000000004669 83.0
HKD2_k127_6607058_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 342.0
HKD2_k127_6607058_1 DDE superfamily endonuclease - - - 0.0008562 43.0
HKD2_k127_6607068_0 peroxiredoxin, OsmC subfamily K04063 - - 0.0000000000000000000000000000000000000000000003155 170.0
HKD2_k127_6607068_1 C4-dicarboxylate transmembrane transporter activity K07791,K07792 - - 0.0000000000000000000000000000000000000004274 149.0
HKD2_k127_6607068_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0000000000000000000000006383 103.0
HKD2_k127_6608000_0 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 7.716e-256 811.0
HKD2_k127_6608000_1 histidine kinase HAMP region domain protein K03406 - - 1.736e-237 752.0
HKD2_k127_6608000_2 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 451.0
HKD2_k127_6608000_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 414.0
HKD2_k127_6608000_4 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 291.0
HKD2_k127_6608000_5 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005682 276.0
HKD2_k127_6608000_7 Two component signalling adaptor domain K03408 - - 0.0000000000000000001362 89.0
HKD2_k127_6615622_0 Aminotransferase class-V K04487 - 2.8.1.7 0.0 1350.0
HKD2_k127_6615622_1 SMART Elongator protein 3 MiaB NifB - - - 9.099e-243 756.0
HKD2_k127_6615622_10 Bacterial protein of unknown function (DUF922) - - - 0.00000000000000000000000000000000000000000000000000000054 199.0
HKD2_k127_6615622_11 Transcriptional regulator K07726 - - 0.000000000000000000000000000001375 123.0
HKD2_k127_6615622_12 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000000000009502 116.0
HKD2_k127_6615622_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.456e-208 659.0
HKD2_k127_6615622_3 Peptidase family U32 - - - 6.9e-206 651.0
HKD2_k127_6615622_4 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 559.0
HKD2_k127_6615622_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 462.0
HKD2_k127_6615622_6 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 458.0
HKD2_k127_6615622_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 304.0
HKD2_k127_6615622_8 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001569 253.0
HKD2_k127_6615622_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000003644 212.0
HKD2_k127_6620575_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000001394 210.0
HKD2_k127_6632194_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1157.0
HKD2_k127_6632194_1 Ferredoxin - - - 0.0000000000000000000000000000000000000000009035 162.0
HKD2_k127_6632194_4 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000003292 78.0
HKD2_k127_6633534_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 0.0 1519.0
HKD2_k127_6633534_1 AcrB/AcrD/AcrF family K03296,K19594 - - 0.0 1466.0
HKD2_k127_6633534_10 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 318.0
HKD2_k127_6633534_11 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 309.0
HKD2_k127_6633534_12 electron transfer activity K05337 - - 0.00000000000000000000000000000000000001374 144.0
HKD2_k127_6633534_14 Cytochrome c K08906,K12263 - - 0.000000000000000000000000000000006012 132.0
HKD2_k127_6633534_2 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.0 1022.0
HKD2_k127_6633534_3 Belongs to the thiolase family K00626 - 2.3.1.9 3.064e-257 801.0
HKD2_k127_6633534_4 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 1.406e-212 670.0
HKD2_k127_6633534_5 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 589.0
HKD2_k127_6633534_6 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 552.0
HKD2_k127_6633534_7 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 523.0
HKD2_k127_6633534_8 Biotin-lipoyl like K19595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 416.0
HKD2_k127_6633534_9 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 389.0
HKD2_k127_6641858_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.606e-286 880.0
HKD2_k127_6641858_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 1.134e-280 867.0
HKD2_k127_6641858_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 508.0
HKD2_k127_6641858_3 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 438.0
HKD2_k127_6641858_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 362.0
HKD2_k127_6641858_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 320.0
HKD2_k127_6693349_0 DEAD_2 K10844 - 3.6.4.12 9.803e-266 827.0
HKD2_k127_6693349_1 Histidine kinase K13040 - 2.7.13.3 5.164e-228 721.0
HKD2_k127_6693349_2 FIST N domain - - - 2.306e-207 649.0
HKD2_k127_6700384_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1292.0
HKD2_k127_6700384_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 1.522e-316 968.0
HKD2_k127_6700384_10 Thioesterase superfamily - - - 0.000000000000000000000000000000000504 136.0
HKD2_k127_6700384_11 Mycolic acid cyclopropane synthetase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000002204 111.0
HKD2_k127_6700384_12 Opacity family porin protein - - - 0.000000000000002454 83.0
HKD2_k127_6700384_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 511.0
HKD2_k127_6700384_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 355.0
HKD2_k127_6700384_4 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 326.0
HKD2_k127_6700384_5 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 295.0
HKD2_k127_6700384_6 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000000000003446 218.0
HKD2_k127_6700384_7 Helix-turn-helix domain of resolvase - - - 0.0000000000000000000000000000000000000000000000000001848 192.0
HKD2_k127_6700384_8 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000007656 181.0
HKD2_k127_6700384_9 - - - - 0.000000000000000000000000000000000000006997 148.0
HKD2_k127_6705091_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 2029.0
HKD2_k127_6705091_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 294.0
HKD2_k127_6705091_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000005894 164.0
HKD2_k127_6705091_3 Domain of unknown function (DUF1858) - - - 0.00000000000000000000000000000003872 125.0
HKD2_k127_6709710_0 gluconolactonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 482.0
HKD2_k127_6709710_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000001551 167.0
HKD2_k127_6711863_0 DNA-sulfur modification-associated K19169 - - 0.000002044 59.0
HKD2_k127_6711863_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.0001945 46.0
HKD2_k127_6714531_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2151.0
HKD2_k127_6714531_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1751.0
HKD2_k127_6714531_10 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 3.959e-213 670.0
HKD2_k127_6714531_11 PFAM Type II secretion system protein E K02669 - - 1.072e-210 657.0
HKD2_k127_6714531_12 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 599.0
HKD2_k127_6714531_13 Nucleotide cyclase, HAMP and GGDEF-related domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 569.0
HKD2_k127_6714531_14 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 391.0
HKD2_k127_6714531_15 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 370.0
HKD2_k127_6714531_16 Predicted methyltransferase regulatory domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 345.0
HKD2_k127_6714531_17 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 312.0
HKD2_k127_6714531_18 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 304.0
HKD2_k127_6714531_19 Belongs to the UPF0502 family K09915 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 280.0
HKD2_k127_6714531_2 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1366.0
HKD2_k127_6714531_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002126 273.0
HKD2_k127_6714531_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003217 247.0
HKD2_k127_6714531_23 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000004889 199.0
HKD2_k127_6714531_24 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000024 188.0
HKD2_k127_6714531_25 Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000000000000000007682 183.0
HKD2_k127_6714531_26 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000000001432 166.0
HKD2_k127_6714531_28 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000002188 175.0
HKD2_k127_6714531_29 GGDEF domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000005388 154.0
HKD2_k127_6714531_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1250.0
HKD2_k127_6714531_30 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000000000003131 131.0
HKD2_k127_6714531_32 cell envelope organization K05807,K08309 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000007921 124.0
HKD2_k127_6714531_4 Cytochrome c3 - - - 0.0 1124.0
HKD2_k127_6714531_5 radical SAM domain protein - - - 4.336e-272 855.0
HKD2_k127_6714531_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.209e-264 824.0
HKD2_k127_6714531_7 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 1.197e-233 729.0
HKD2_k127_6714531_8 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 8.399e-222 691.0
HKD2_k127_6714531_9 DNA-binding transcription factor activity K02274 - 1.9.3.1 3.589e-215 682.0
HKD2_k127_6717756_0 Fic/DOC family - - - 2.636e-251 779.0
HKD2_k127_6717756_1 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 601.0
HKD2_k127_6717756_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 475.0
HKD2_k127_6717756_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 426.0
HKD2_k127_6717756_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 310.0
HKD2_k127_6717756_5 Gaf domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005263 246.0
HKD2_k127_6717756_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000001945 244.0
HKD2_k127_6717756_7 GIY-YIG catalytic domain - - - 0.000000000000000000000000000000007491 133.0
HKD2_k127_6717756_8 PFAM filamentation induced by cAMP protein Fic - - - 0.00000000000000000000000000000003317 126.0
HKD2_k127_6717756_9 PFAM filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000418 123.0
HKD2_k127_6720267_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1929.0
HKD2_k127_6720267_1 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 1.141e-278 859.0
HKD2_k127_6720267_10 DinB superfamily - - - 0.00000000000000000000000002432 115.0
HKD2_k127_6720267_2 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 4.628e-257 799.0
HKD2_k127_6720267_3 PFAM major facilitator superfamily MFS_1 K02575 - - 3.158e-250 778.0
HKD2_k127_6720267_4 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 511.0
HKD2_k127_6720267_5 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 354.0
HKD2_k127_6720267_6 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 319.0
HKD2_k127_6720267_7 cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 297.0
HKD2_k127_6720267_8 Cytochrome c K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000008529 237.0
HKD2_k127_6720267_9 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000006127 206.0
HKD2_k127_6747390_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1035.0
HKD2_k127_6747390_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.78e-295 908.0
HKD2_k127_6747390_10 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 335.0
HKD2_k127_6747390_11 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 293.0
HKD2_k127_6747390_12 PFAM type IV pilus assembly PilZ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 291.0
HKD2_k127_6747390_13 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004377 271.0
HKD2_k127_6747390_14 aspartic-type endopeptidase activity K06985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002587 273.0
HKD2_k127_6747390_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005258 257.0
HKD2_k127_6747390_16 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006366 253.0
HKD2_k127_6747390_2 Flagellar biogenesis master sigma-54-dependent transcriptional response regulator - - - 6.189e-269 833.0
HKD2_k127_6747390_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 599.0
HKD2_k127_6747390_4 Metal-dependent phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 562.0
HKD2_k127_6747390_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 548.0
HKD2_k127_6747390_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 506.0
HKD2_k127_6747390_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 503.0
HKD2_k127_6747390_8 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 516.0
HKD2_k127_6747390_9 EamA-like transporter family K03298 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 387.0
HKD2_k127_6756967_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 4.035e-298 917.0
HKD2_k127_6756967_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 1.038e-223 695.0
HKD2_k127_6756967_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 392.0
HKD2_k127_6756967_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 344.0
HKD2_k127_6756967_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 316.0
HKD2_k127_6756967_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 301.0
HKD2_k127_6756967_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000176 280.0
HKD2_k127_6756967_15 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007463 256.0
HKD2_k127_6756967_16 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000007086 234.0
HKD2_k127_6756967_17 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000008803 229.0
HKD2_k127_6756967_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000003746 184.0
HKD2_k127_6756967_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 593.0
HKD2_k127_6756967_3 Alcohol dehydrogenase GroES-associated K00148 - 1.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 507.0
HKD2_k127_6756967_4 LysR substrate binding domain K02521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 474.0
HKD2_k127_6756967_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 483.0
HKD2_k127_6756967_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 431.0
HKD2_k127_6756967_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 435.0
HKD2_k127_6756967_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 424.0
HKD2_k127_6756967_9 Predicted membrane protein (DUF2232) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 404.0
HKD2_k127_6785408_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1069.0
HKD2_k127_6785408_1 Sodium:solute symporter family K14393 - - 1.145e-266 827.0
HKD2_k127_6785408_2 Putative nucleotidyltransferase substrate binding domain K07182 - - 6.769e-197 620.0
HKD2_k127_6785408_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 485.0
HKD2_k127_6785408_4 signal-transduction protein containing cAMP-binding and CBS domains K02342,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 417.0
HKD2_k127_6785408_5 IclR helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 266.0
HKD2_k127_6785408_6 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000000000000000000000003902 206.0
HKD2_k127_6785408_7 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000006366 110.0
HKD2_k127_6793157_0 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.0000000000000000000000000000000000000000000000000000002424 208.0
HKD2_k127_6819900_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.0 1397.0
HKD2_k127_6819900_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0 1184.0
HKD2_k127_6819900_10 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
HKD2_k127_6819900_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
HKD2_k127_6819900_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002546 276.0
HKD2_k127_6819900_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001853 259.0
HKD2_k127_6819900_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000003595 173.0
HKD2_k127_6819900_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000285 162.0
HKD2_k127_6819900_16 ATP synthase I chain - - - 0.0000000000000000000000000000000000000000002856 162.0
HKD2_k127_6819900_17 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000000000000002319 93.0
HKD2_k127_6819900_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1150.0
HKD2_k127_6819900_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 3.597e-253 783.0
HKD2_k127_6819900_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 9.788e-243 751.0
HKD2_k127_6819900_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.519e-241 750.0
HKD2_k127_6819900_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 2.96e-211 660.0
HKD2_k127_6819900_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 422.0
HKD2_k127_6819900_8 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 399.0
HKD2_k127_6819900_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 343.0
HKD2_k127_6823756_0 Heavy metal transcriptional response regulator K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 344.0
HKD2_k127_6823756_1 Member of a two-component regulatory system K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 304.0
HKD2_k127_6823756_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
HKD2_k127_6823756_3 denitrification pathway - - - 0.000000009115 67.0
HKD2_k127_6823756_4 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000001014 60.0
HKD2_k127_6859438_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1352.0
HKD2_k127_6859438_1 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000959 150.0
HKD2_k127_6949963_0 Belongs to the pseudouridine synthase RluA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 504.0
HKD2_k127_6949963_1 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001163 281.0
HKD2_k127_6949963_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 279.0
HKD2_k127_6949963_3 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000702 255.0
HKD2_k127_6949963_4 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000002517 243.0
HKD2_k127_6984750_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000754 310.0
HKD2_k127_6984750_1 PKD domain containing protein K01179,K07004,K13277,K20276,K21449 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 3.2.1.4 0.000000008326 70.0
HKD2_k127_698744_0 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 1.02e-239 752.0
HKD2_k127_698744_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 6.361e-226 703.0
HKD2_k127_698744_10 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000002882 81.0
HKD2_k127_698744_2 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 472.0
HKD2_k127_698744_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 465.0
HKD2_k127_698744_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 443.0
HKD2_k127_698744_5 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000708 282.0
HKD2_k127_698744_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 258.0
HKD2_k127_698744_7 PFAM histidine triad (HIT) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003198 244.0
HKD2_k127_698744_8 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000001746 181.0
HKD2_k127_698744_9 - - - - 0.000000000000000000006638 92.0
HKD2_k127_698746_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.7e-314 974.0
HKD2_k127_698746_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 9.514e-216 681.0
HKD2_k127_698746_10 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000059 213.0
HKD2_k127_698746_11 Acyl carrier protein - - - 0.0000000000000000000000000000797 122.0
HKD2_k127_698746_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.883e-196 615.0
HKD2_k127_698746_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 610.0
HKD2_k127_698746_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 496.0
HKD2_k127_698746_5 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 433.0
HKD2_k127_698746_6 formate dehydrogenase K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
HKD2_k127_698746_7 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 334.0
HKD2_k127_698746_8 PFAM type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005137 269.0
HKD2_k127_698746_9 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 263.0
HKD2_k127_6994109_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.443e-225 701.0
HKD2_k127_6994109_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 539.0
HKD2_k127_6994109_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 386.0
HKD2_k127_6994109_3 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000004736 77.0
HKD2_k127_7007584_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 316.0
HKD2_k127_7103293_0 PFAM C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.00000000000000000000000000000000000000000000000000000008125 203.0
HKD2_k127_7115511_0 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 528.0
HKD2_k127_7115511_1 of the double-stranded beta helix - - - 0.00001903 49.0
HKD2_k127_7160654_0 transposase activity - - - 0.0000000000000000003159 101.0
HKD2_k127_7160654_1 TIR domain - - - 0.0000003026 51.0
HKD2_k127_7204766_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000001622 190.0
HKD2_k127_7204766_1 cellulose binding - - - 0.00000001988 66.0
HKD2_k127_7207985_0 - K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 478.0
HKD2_k127_7247555_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1630.0
HKD2_k127_7247555_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1149.0
HKD2_k127_7247555_2 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 8.873e-198 616.0
HKD2_k127_7247555_3 Protein of unknown function (DUF327) K09770 - - 0.00000000000000000000000000000000000000000000000000000000000000003837 228.0
HKD2_k127_7247555_4 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000009864 124.0
HKD2_k127_7247555_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 0.00000000000000000000004909 104.0
HKD2_k127_7263941_0 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0 1072.0
HKD2_k127_7263941_1 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1068.0
HKD2_k127_7263941_10 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 603.0
HKD2_k127_7263941_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 529.0
HKD2_k127_7263941_12 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 517.0
HKD2_k127_7263941_13 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 488.0
HKD2_k127_7263941_14 Methyltransferase type 11 K03892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 473.0
HKD2_k127_7263941_15 ThiF family K03148 - 2.7.7.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 465.0
HKD2_k127_7263941_16 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 433.0
HKD2_k127_7263941_18 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
HKD2_k127_7263941_19 PFAM MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001191 261.0
HKD2_k127_7263941_2 4Fe-4S dicluster domain - - - 0.0 1029.0
HKD2_k127_7263941_21 Shikimate kinase K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
HKD2_k127_7263941_22 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
HKD2_k127_7263941_23 - - - - 0.00000000000000000000000000000000000364 145.0
HKD2_k127_7263941_24 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000001026 152.0
HKD2_k127_7263941_25 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000000000002915 132.0
HKD2_k127_7263941_26 Mo-molybdopterin cofactor metabolic process K03154 - - 0.000000000000000000000000000002643 121.0
HKD2_k127_7263941_27 LPP20 lipoprotein - - - 0.00000000000000000000002949 111.0
HKD2_k127_7263941_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 3.992e-299 919.0
HKD2_k127_7263941_4 electron transfer flavoprotein, alpha subunit K03522 - - 8.909e-242 751.0
HKD2_k127_7263941_5 SMART Elongator protein 3 MiaB NifB - - - 6.315e-233 726.0
HKD2_k127_7263941_6 PFAM iron-containing alcohol dehydrogenase K13954 - 1.1.1.1 2.786e-232 721.0
HKD2_k127_7263941_7 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 6.821e-203 636.0
HKD2_k127_7263941_8 Putative metallopeptidase domain - - - 3.963e-202 635.0
HKD2_k127_7263941_9 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 610.0
HKD2_k127_7341436_0 Resolvase, RNase H domain protein fold K06959 - - 0.0 1257.0
HKD2_k127_7341436_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1142.0
HKD2_k127_7341436_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 536.0
HKD2_k127_7341436_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005912 242.0
HKD2_k127_7341436_4 PFAM phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000000000000000000000000000000000001515 228.0
HKD2_k127_7341436_5 PFAM FeoA family protein K04758 - - 0.00000000000000000000000000000002935 128.0
HKD2_k127_7341436_6 PFAM FeoA family protein K04758 - - 0.00000000000000000001308 96.0
HKD2_k127_7341436_7 - - - - 0.0000000000000003142 79.0
HKD2_k127_7341436_9 SNARE associated Golgi protein - - - 0.0001416 44.0
HKD2_k127_7374201_0 PFAM ROK family protein K00845,K00847 - 2.7.1.2,2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 388.0
HKD2_k127_7425233_0 PFAM Polysaccharide export protein - - - 1.922e-314 989.0
HKD2_k127_7425233_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 2.184e-201 632.0
HKD2_k127_7425233_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 467.0
HKD2_k127_7425233_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 444.0
HKD2_k127_7425233_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 289.0
HKD2_k127_7425233_5 PFAM ROSMUCR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 282.0
HKD2_k127_7425233_6 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000000000000000000716 134.0
HKD2_k127_7425233_7 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000001324 64.0
HKD2_k127_7425233_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0001545 47.0
HKD2_k127_7442098_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 460.0
HKD2_k127_7444850_0 Collagenase K08303 - - 0.0 1324.0
HKD2_k127_7444850_1 PFAM peptidase M16 domain protein K07263 - - 7.758e-231 720.0
HKD2_k127_7444850_11 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000002812 64.0
HKD2_k127_7444850_2 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 2.199e-197 619.0
HKD2_k127_7444850_3 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 468.0
HKD2_k127_7444850_4 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 452.0
HKD2_k127_7444850_5 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 334.0
HKD2_k127_7444850_6 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 299.0
HKD2_k127_7444850_8 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
HKD2_k127_7444850_9 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
HKD2_k127_751299_0 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 441.0
HKD2_k127_759591_0 PFAM MULE transposase, conserved domain - - - 0.0000000000000000000000000000000000000000000348 174.0
HKD2_k127_764344_0 Heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 329.0
HKD2_k127_764344_1 Cys Met metabolism K01760 - 4.4.1.8 0.0000000000001722 70.0
HKD2_k127_7693673_0 - - - - 0.0000000000000000000000000000000000003823 145.0
HKD2_k127_7698212_0 DEAD DEAH box K03724 - - 0.0 1753.0
HKD2_k127_7698212_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.679e-260 807.0
HKD2_k127_7698212_2 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 610.0
HKD2_k127_7698212_3 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 366.0
HKD2_k127_7698212_4 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 306.0
HKD2_k127_7698971_0 PFAM transposase IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 545.0
HKD2_k127_7700854_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 603.0
HKD2_k127_7700854_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.1.1.205,1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 595.0
HKD2_k127_7700854_11 Protein of unknown function (DUF2288) - - - 0.00000000000000000000000000000000000000002596 153.0
HKD2_k127_7700854_12 Transcriptional regulator - - - 0.00000000000000000000000000000001085 129.0
HKD2_k127_7700854_2 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 591.0
HKD2_k127_7700854_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 538.0
HKD2_k127_7700854_4 PFAM flagellin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 438.0
HKD2_k127_7700854_5 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 423.0
HKD2_k127_7700854_6 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 389.0
HKD2_k127_7700854_7 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 332.0
HKD2_k127_7700854_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003558 276.0
HKD2_k127_7700854_9 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001483 269.0
HKD2_k127_7708727_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2321.0
HKD2_k127_7708727_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2111.0
HKD2_k127_7708727_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1330.0
HKD2_k127_7708727_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 302.0
HKD2_k127_7708727_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001264 246.0
HKD2_k127_7708727_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000003466 205.0
HKD2_k127_7717205_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 1.474e-200 635.0
HKD2_k127_7717205_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000007213 83.0
HKD2_k127_7722841_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1502.0
HKD2_k127_7722841_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 7.001e-268 837.0
HKD2_k127_7722841_10 TIGRFAM polysaccharide chain length determinant protein, PEP-CTERM locus subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 598.0
HKD2_k127_7722841_11 winged helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 586.0
HKD2_k127_7722841_12 PFAM Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 578.0
HKD2_k127_7722841_13 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 573.0
HKD2_k127_7722841_14 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 525.0
HKD2_k127_7722841_15 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 505.0
HKD2_k127_7722841_16 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 501.0
HKD2_k127_7722841_17 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 458.0
HKD2_k127_7722841_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 460.0
HKD2_k127_7722841_19 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 441.0
HKD2_k127_7722841_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.509e-252 786.0
HKD2_k127_7722841_20 -O-antigen K02847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 451.0
HKD2_k127_7722841_21 Secretion ATPase, PEP-CTERM locus subfamily K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 445.0
HKD2_k127_7722841_22 TIGRFAM FemAB-related protein, PEP-CTERM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 436.0
HKD2_k127_7722841_23 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 430.0
HKD2_k127_7722841_24 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 411.0
HKD2_k127_7722841_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 413.0
HKD2_k127_7722841_26 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 391.0
HKD2_k127_7722841_27 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 397.0
HKD2_k127_7722841_28 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 390.0
HKD2_k127_7722841_29 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 382.0
HKD2_k127_7722841_3 Peptidase family M1 domain - - - 3.56e-250 793.0
HKD2_k127_7722841_30 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 345.0
HKD2_k127_7722841_31 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 348.0
HKD2_k127_7722841_32 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
HKD2_k127_7722841_33 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 331.0
HKD2_k127_7722841_34 Capsular exopolysaccharide family K08252 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 325.0
HKD2_k127_7722841_35 Protein of unknown function (DUF1573) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 309.0
HKD2_k127_7722841_36 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 325.0
HKD2_k127_7722841_37 PFAM ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 301.0
HKD2_k127_7722841_38 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 286.0
HKD2_k127_7722841_39 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003139 291.0
HKD2_k127_7722841_4 - - - - 4.662e-239 744.0
HKD2_k127_7722841_40 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001101 284.0
HKD2_k127_7722841_41 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001261 276.0
HKD2_k127_7722841_42 PFAM GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001218 263.0
HKD2_k127_7722841_44 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000003444 243.0
HKD2_k127_7722841_45 serine acetyltransferase K00640,K03819 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000002209 258.0
HKD2_k127_7722841_46 Transport permease protein K09688,K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000009464 236.0
HKD2_k127_7722841_47 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.00000000000000000000000000000000000000000000000000000000000001418 218.0
HKD2_k127_7722841_48 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000001605 199.0
HKD2_k127_7722841_49 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000968 201.0
HKD2_k127_7722841_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 9.927e-214 670.0
HKD2_k127_7722841_50 Domain of unknown function (DUF1904) - - - 0.000000000000000000000000000000000000000000883 160.0
HKD2_k127_7722841_51 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000002207 169.0
HKD2_k127_7722841_53 nuclear chromosome segregation - - - 0.000000000000000000000000000000346 138.0
HKD2_k127_7722841_54 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000003257 127.0
HKD2_k127_7722841_55 - - - - 0.000000000000000000000009787 106.0
HKD2_k127_7722841_56 Belongs to the peptidase S8 family - - - 0.00000000000000000000004044 113.0
HKD2_k127_7722841_57 extracellular matrix structural constituent - - - 0.00000000000000009391 95.0
HKD2_k127_7722841_58 - - - - 0.0000000000001624 78.0
HKD2_k127_7722841_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 2.599e-210 659.0
HKD2_k127_7722841_60 GDSL-like Lipase/Acylhydrolase family - - - 0.000003191 59.0
HKD2_k127_7722841_62 fibronectin type III domain protein - - - 0.0006291 42.0
HKD2_k127_7722841_7 Peptidase dimerisation domain K01436 - - 2.621e-206 647.0
HKD2_k127_7722841_8 PFAM aminotransferase class-III K01845 - 5.4.3.8 2.443e-195 617.0
HKD2_k127_7722841_9 Putative zinc binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 601.0
HKD2_k127_7723833_0 Belongs to the beta-ketoacyl-ACP synthases family - - - 2.536e-284 878.0
HKD2_k127_7747020_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K11389 - 1.2.7.6 0.0 1131.0
HKD2_k127_7747020_1 Protein of unknown function (DUF4239) - - - 0.00005127 46.0
HKD2_k127_7754163_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 3.9e-322 993.0
HKD2_k127_7754163_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.042e-253 784.0
HKD2_k127_7754163_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 449.0
HKD2_k127_7754163_3 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 350.0
HKD2_k127_7754163_4 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001863 245.0
HKD2_k127_7754163_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000001357 211.0
HKD2_k127_7754163_6 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000001424 197.0
HKD2_k127_7754163_7 - - - - 0.000000000000001482 84.0
HKD2_k127_7754163_9 - - - - 0.00005571 47.0
HKD2_k127_7767827_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1742.0
HKD2_k127_7767827_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.839e-302 932.0
HKD2_k127_7767827_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 396.0
HKD2_k127_7767827_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 392.0
HKD2_k127_7767827_12 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 379.0
HKD2_k127_7767827_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 359.0
HKD2_k127_7767827_14 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 344.0
HKD2_k127_7767827_15 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 313.0
HKD2_k127_7767827_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
HKD2_k127_7767827_17 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 292.0
HKD2_k127_7767827_18 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000397 279.0
HKD2_k127_7767827_19 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006961 269.0
HKD2_k127_7767827_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.793e-263 815.0
HKD2_k127_7767827_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004536 261.0
HKD2_k127_7767827_21 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009877 261.0
HKD2_k127_7767827_22 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001288 260.0
HKD2_k127_7767827_23 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 254.0
HKD2_k127_7767827_24 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000009546 240.0
HKD2_k127_7767827_25 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001544 230.0
HKD2_k127_7767827_26 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000002534 213.0
HKD2_k127_7767827_27 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000003472 205.0
HKD2_k127_7767827_28 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004014 205.0
HKD2_k127_7767827_29 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002317 196.0
HKD2_k127_7767827_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 2.253e-225 702.0
HKD2_k127_7767827_30 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000002599 192.0
HKD2_k127_7767827_31 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000006837 178.0
HKD2_k127_7767827_32 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000005026 175.0
HKD2_k127_7767827_33 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000004875 160.0
HKD2_k127_7767827_34 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000001616 128.0
HKD2_k127_7767827_35 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000006709 125.0
HKD2_k127_7767827_36 PFAM ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000208 105.0
HKD2_k127_7767827_38 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000002608 76.0
HKD2_k127_7767827_39 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000008137 60.0
HKD2_k127_7767827_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 2.403e-215 669.0
HKD2_k127_7767827_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 574.0
HKD2_k127_7767827_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 522.0
HKD2_k127_7767827_7 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 419.0
HKD2_k127_7767827_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 408.0
HKD2_k127_7767827_9 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 402.0
HKD2_k127_7769691_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.0 1067.0
HKD2_k127_7769691_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 542.0
HKD2_k127_7769691_2 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 451.0
HKD2_k127_7769691_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 284.0
HKD2_k127_7769691_4 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000003531 235.0
HKD2_k127_7773514_0 helicase domain protein - - - 0.0 1866.0
HKD2_k127_7773514_1 PFAM SNF2-related protein - - - 0.0 1471.0
HKD2_k127_7773514_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000009258 222.0
HKD2_k127_7773514_11 lactoylglutathione lyase activity K01239,K08234 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000248 197.0
HKD2_k127_7773514_12 TIGRFAM addiction module toxin, RelE StbE family K19092 - - 0.000000000000000000000001384 105.0
HKD2_k127_7773514_13 bacterial-type proximal promoter sequence-specific DNA binding K07473 - - 0.00000001266 61.0
HKD2_k127_7773514_2 - - - - 1.253e-220 692.0
HKD2_k127_7773514_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 596.0
HKD2_k127_7773514_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 528.0
HKD2_k127_7773514_5 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 414.0
HKD2_k127_7773514_6 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 411.0
HKD2_k127_7773514_7 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 365.0
HKD2_k127_7773514_8 anti-sigma regulatory factor K04757 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004679 248.0
HKD2_k127_7780713_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.0 1120.0
HKD2_k127_7793385_0 Cytochrome c3 - - - 0.0 1033.0
HKD2_k127_7793385_1 PFAM ABC transporter related - - - 0.0 1006.0
HKD2_k127_7793385_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 329.0
HKD2_k127_7793385_11 beta-galactosidase activity K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 308.0
HKD2_k127_7793385_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001278 276.0
HKD2_k127_7793385_13 DNA-binding transcription factor activity K21900 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006857 282.0
HKD2_k127_7793385_14 PFAM Desulfoferrodoxin, ferrous iron-binding region K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000005132 213.0
HKD2_k127_7793385_15 - - - - 0.00000000000000000000000000000000000000000000000001571 186.0
HKD2_k127_7793385_16 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions - - - 0.00000000000000000000000000000000000000000000003639 175.0
HKD2_k127_7793385_17 - - - - 0.000000000000000000000000000000000000003253 149.0
HKD2_k127_7793385_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 2.282e-216 679.0
HKD2_k127_7793385_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 603.0
HKD2_k127_7793385_4 histidine kinase HAMP region domain protein K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 610.0
HKD2_k127_7793385_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 472.0
HKD2_k127_7793385_6 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
HKD2_k127_7793385_7 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 458.0
HKD2_k127_7793385_8 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 438.0
HKD2_k127_7793385_9 response regulator K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 376.0
HKD2_k127_7796150_0 PFAM alpha amylase catalytic region K05343 - 3.2.1.1,5.4.99.16 0.0 1794.0
HKD2_k127_7796150_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1452.0
HKD2_k127_7796150_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1354.0
HKD2_k127_7796150_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0 1008.0
HKD2_k127_7796150_4 glycoside hydrolase, family 13 domain protein K01236 - 3.2.1.141 7.344e-306 947.0
HKD2_k127_7796150_5 Ribonuclease, BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 425.0
HKD2_k127_7796150_6 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000008764 145.0
HKD2_k127_7796429_0 - - - - 3.84e-287 894.0
HKD2_k127_7807638_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 7.446e-315 970.0
HKD2_k127_7807638_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.954e-265 818.0
HKD2_k127_7807638_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 479.0
HKD2_k127_7807638_11 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 477.0
HKD2_k127_7807638_12 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 453.0
HKD2_k127_7807638_13 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 441.0
HKD2_k127_7807638_14 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 432.0
HKD2_k127_7807638_15 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 415.0
HKD2_k127_7807638_16 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 407.0
HKD2_k127_7807638_17 PFAM EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 402.0
HKD2_k127_7807638_18 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 389.0
HKD2_k127_7807638_19 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 387.0
HKD2_k127_7807638_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 6.961e-249 772.0
HKD2_k127_7807638_20 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 390.0
HKD2_k127_7807638_21 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 364.0
HKD2_k127_7807638_22 the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 353.0
HKD2_k127_7807638_23 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 268.0
HKD2_k127_7807638_24 Pyruvate kinase, alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001251 266.0
HKD2_k127_7807638_25 PFAM Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009151 254.0
HKD2_k127_7807638_26 Protein of unknown function (DUF563) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004744 254.0
HKD2_k127_7807638_27 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000001184 226.0
HKD2_k127_7807638_28 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000000000001799 195.0
HKD2_k127_7807638_29 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000000000000000000002125 192.0
HKD2_k127_7807638_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.295e-242 757.0
HKD2_k127_7807638_30 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000007706 170.0
HKD2_k127_7807638_31 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000000000001032 143.0
HKD2_k127_7807638_32 Adenylylsulphate kinase - - - 0.00000000000000000000000000000000001744 145.0
HKD2_k127_7807638_33 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000002425 119.0
HKD2_k127_7807638_34 Methyltransferase domain - - - 0.000000000000000000000009169 113.0
HKD2_k127_7807638_35 - K07090 - - 0.00000000000000000001801 101.0
HKD2_k127_7807638_36 Methyltransferase FkbM domain - - - 0.000000000000000003191 95.0
HKD2_k127_7807638_37 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01953 - 6.3.5.4 0.000001979 49.0
HKD2_k127_7807638_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 1.966e-206 645.0
HKD2_k127_7807638_5 Glycosyl transferase, family 2 - - - 1.947e-205 654.0
HKD2_k127_7807638_6 Sigma-70 factor, region 1.1 K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 548.0
HKD2_k127_7807638_7 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 528.0
HKD2_k127_7807638_8 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 528.0
HKD2_k127_7807638_9 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 511.0
HKD2_k127_7821863_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 3.594e-292 908.0
HKD2_k127_7821863_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 592.0
HKD2_k127_7821863_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 364.0
HKD2_k127_7821863_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 357.0
HKD2_k127_7821863_4 Post-segregation antitoxin CcdA K19164 - - 0.00007818 50.0
HKD2_k127_7821863_5 - - - - 0.0001219 48.0
HKD2_k127_7826029_0 Radical SAM domain protein K03424 - - 1.999e-254 790.0
HKD2_k127_7826029_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000007507 143.0
HKD2_k127_7826029_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000001658 79.0
HKD2_k127_7830080_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0 1038.0
HKD2_k127_7830080_1 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 372.0
HKD2_k127_7866542_0 - - - - 0.00000000000000000000000000003808 124.0
HKD2_k127_7917077_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1824.0
HKD2_k127_7917077_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.897e-304 940.0
HKD2_k127_7917077_10 Bacterial Ig-like domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 325.0
HKD2_k127_7917077_11 4-vinyl reductase, 4VR K07013,K17763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003184 258.0
HKD2_k127_7917077_12 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000002381 200.0
HKD2_k127_7917077_13 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000000009368 177.0
HKD2_k127_7917077_15 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000007442 155.0
HKD2_k127_7917077_16 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000000000005281 141.0
HKD2_k127_7917077_2 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 3.819e-230 732.0
HKD2_k127_7917077_3 Aromatic amino acid lyase K01745 - 4.3.1.3 5.028e-229 723.0
HKD2_k127_7917077_4 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 559.0
HKD2_k127_7917077_5 transmembrane signaling receptor activity K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 541.0
HKD2_k127_7917077_6 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 535.0
HKD2_k127_7917077_7 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 496.0
HKD2_k127_7917077_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 478.0
HKD2_k127_7917077_9 Belongs to the arginase family K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 364.0
HKD2_k127_7918969_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 510.0
HKD2_k127_7918969_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 479.0
HKD2_k127_7918969_2 Cupin 2, conserved barrel domain protein K00971,K01809,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000003429 232.0
HKD2_k127_7942003_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1303.0
HKD2_k127_7942003_1 Elongation factor SelB winged helix 3 K03833 - - 0.0 1135.0
HKD2_k127_7942003_10 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 587.0
HKD2_k127_7942003_11 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 547.0
HKD2_k127_7942003_12 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 536.0
HKD2_k127_7942003_13 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 527.0
HKD2_k127_7942003_14 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 518.0
HKD2_k127_7942003_15 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 512.0
HKD2_k127_7942003_16 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 507.0
HKD2_k127_7942003_17 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 478.0
HKD2_k127_7942003_18 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 378.0
HKD2_k127_7942003_19 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 330.0
HKD2_k127_7942003_2 - - - - 0.0 1103.0
HKD2_k127_7942003_20 Papain cysteine protease family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 313.0
HKD2_k127_7942003_21 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000005121 211.0
HKD2_k127_7942003_22 PIN domain - - - 0.000000000000000000000000000000000000008263 149.0
HKD2_k127_7942003_23 DNA methylase K07316 - 2.1.1.72 0.00000000000000000000000000000000006799 145.0
HKD2_k127_7942003_24 DNA methylase K07316 - 2.1.1.72 0.0000000000000000000000000000000002217 139.0
HKD2_k127_7942003_27 positive regulation of growth - - - 0.00000000000000000000005749 102.0
HKD2_k127_7942003_28 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003920,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015949,GO:0015950,GO:0015951,GO:0016491,GO:0016651,GO:0016657,GO:0019637,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.1.1.205,1.7.1.7 0.000000000000000000787 85.0
HKD2_k127_7942003_29 Protein of unknown function (DUF2845) - - - 0.00000000000000001999 93.0
HKD2_k127_7942003_3 ABC transporter transmembrane region K06147,K18890 - - 2.34e-316 975.0
HKD2_k127_7942003_30 metallopeptidase activity - - - 0.00004016 55.0
HKD2_k127_7942003_4 ABC transporter transmembrane region K06147,K18889 - - 1.242e-289 898.0
HKD2_k127_7942003_5 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.331e-263 818.0
HKD2_k127_7942003_6 PFAM chemotaxis sensory transducer K03406 - - 7.815e-232 728.0
HKD2_k127_7942003_7 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 2.895e-217 679.0
HKD2_k127_7942003_8 Glucose dehydrogenase C-terminus K00008,K00060 - 1.1.1.103,1.1.1.14 1.743e-209 653.0
HKD2_k127_7942003_9 PFAM aminotransferase class I and II K14155 - 4.4.1.8 2.15e-204 641.0
HKD2_k127_7945495_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 313.0
HKD2_k127_7945495_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000345 251.0
HKD2_k127_7952805_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 4.622e-243 752.0
HKD2_k127_7952805_1 regulatory protein LysR K02019 - - 0.000000000000000000000000000000000000000000000000000000000026 210.0
HKD2_k127_7952805_2 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000001311 83.0
HKD2_k127_7952805_3 Putative regulatory protein - - - 0.00000000003732 66.0
HKD2_k127_7962278_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 495.0
HKD2_k127_7962278_1 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000001271 73.0
HKD2_k127_7964512_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.631e-319 980.0
HKD2_k127_7964512_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.203e-268 828.0
HKD2_k127_7964512_10 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 352.0
HKD2_k127_7964512_11 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 310.0
HKD2_k127_7964512_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005337 255.0
HKD2_k127_7964512_13 PFAM Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000001721 246.0
HKD2_k127_7964512_16 - - - - 0.00007093 47.0
HKD2_k127_7964512_2 PFAM ResB family protein K07399 - - 2.334e-252 783.0
HKD2_k127_7964512_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 2.209e-246 768.0
HKD2_k127_7964512_4 Belongs to the GARS family K01945 - 6.3.4.13 7.116e-246 764.0
HKD2_k127_7964512_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 1.353e-214 670.0
HKD2_k127_7964512_6 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 608.0
HKD2_k127_7964512_7 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 542.0
HKD2_k127_7964512_8 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 504.0
HKD2_k127_7964512_9 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 443.0
HKD2_k127_7966495_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1574.0
HKD2_k127_7966495_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0043085,GO:0043546,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050790,GO:0065007,GO:0065009,GO:0097159,GO:0097163,GO:0140104,GO:1901363 - 2.867e-235 734.0
HKD2_k127_7966495_2 PFAM Polysulphide reductase, NrfD - - - 8.82e-227 706.0
HKD2_k127_7966495_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 538.0
HKD2_k127_7966495_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000002951 202.0
HKD2_k127_7966495_5 translation initiation factor activity K07126,K08930 - - 0.0000000000000000000000002375 108.0
HKD2_k127_7966495_6 protein secretion K03116 - - 0.000000000000000000000002375 103.0
HKD2_k127_7972289_0 NUBPL iron-transfer P-loop NTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 607.0
HKD2_k127_7977077_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1069.0
HKD2_k127_7977077_1 thiamine pyrophosphate protein TPP binding domain protein K01652 - 2.2.1.6 0.0 1023.0
HKD2_k127_7977077_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.631e-298 919.0
HKD2_k127_7977077_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 5.197e-214 668.0
HKD2_k127_7977077_4 PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 591.0
HKD2_k127_7977077_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 476.0
HKD2_k127_7977077_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 365.0
HKD2_k127_7977077_7 PFAM Peptidase M22, glycoprotease K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 362.0
HKD2_k127_7977077_8 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 309.0
HKD2_k127_7977077_9 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000114 222.0
HKD2_k127_7983154_0 DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000003515 221.0
HKD2_k127_7983154_1 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000001638 148.0
HKD2_k127_7986743_0 PrkA AAA domain protein - - - 0.0 1379.0
HKD2_k127_7986743_1 Serine protein kinase K07180 - - 0.0 1290.0
HKD2_k127_7986743_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 8.339e-197 616.0
HKD2_k127_7986743_11 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 3.673e-195 612.0
HKD2_k127_7986743_12 Domain of unknown function (DUF4403) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 576.0
HKD2_k127_7986743_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 546.0
HKD2_k127_7986743_14 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 526.0
HKD2_k127_7986743_15 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 497.0
HKD2_k127_7986743_16 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 507.0
HKD2_k127_7986743_17 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD2_k127_7986743_18 response regulator K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 447.0
HKD2_k127_7986743_19 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 358.0
HKD2_k127_7986743_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0 1011.0
HKD2_k127_7986743_20 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007992 275.0
HKD2_k127_7986743_21 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000000000001004 184.0
HKD2_k127_7986743_23 Protein of unknown function (DUF507) - - - 0.0000000000000000000000000000000000000000000002822 169.0
HKD2_k127_7986743_24 Protein of unknown function (DUF507) - - - 0.00000000000000000000000000000000003453 140.0
HKD2_k127_7986743_25 manually curated - - - 0.000000000000000000000000000001235 123.0
HKD2_k127_7986743_26 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000006016 86.0
HKD2_k127_7986743_28 - - - - 0.00000000005621 65.0
HKD2_k127_7986743_29 PFAM GGDEF domain containing protein - - - 0.00002046 53.0
HKD2_k127_7986743_3 PFAM SpoVR family protein K06415 - - 7.267e-317 977.0
HKD2_k127_7986743_4 Belongs to the UPF0229 family K09786 - - 4.216e-268 829.0
HKD2_k127_7986743_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.191e-230 717.0
HKD2_k127_7986743_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 3.424e-230 719.0
HKD2_k127_7986743_7 3'-5' exonuclease K03684 - 3.1.13.5 2.171e-210 659.0
HKD2_k127_7986743_8 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 2.277e-200 626.0
HKD2_k127_7986743_9 deoxyhypusine monooxygenase activity - - - 7.493e-197 629.0
HKD2_k127_7990461_0 Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 569.0
HKD2_k127_7990461_1 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000002079 230.0
HKD2_k127_8026548_0 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.937e-279 861.0
HKD2_k127_8026548_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 3.068e-275 852.0
HKD2_k127_8026548_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005649 276.0
HKD2_k127_8026548_11 PFAM Uncharacterised protein family UPF0150 K18843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 252.0
HKD2_k127_8026548_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001656 238.0
HKD2_k127_8026548_13 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000000000000005132 236.0
HKD2_k127_8026548_14 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000008843 233.0
HKD2_k127_8026548_15 - - - - 0.00000000000000000000000000000000000000000000000000008012 188.0
HKD2_k127_8026548_16 Roadblock/LC7 domain - - - 0.00000000000000000000000002812 111.0
HKD2_k127_8026548_17 Periplasmic or secreted lipoprotein - - - 0.00001153 49.0
HKD2_k127_8026548_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 3.151e-236 735.0
HKD2_k127_8026548_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 600.0
HKD2_k127_8026548_4 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 544.0
HKD2_k127_8026548_5 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 543.0
HKD2_k127_8026548_6 DEAD DEAH box K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 496.0
HKD2_k127_8026548_7 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 447.0
HKD2_k127_8026548_8 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 441.0
HKD2_k127_8026548_9 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002452 272.0
HKD2_k127_8030318_0 histidine kinase HAMP region domain protein K03406 - - 0.0 1255.0
HKD2_k127_8059590_0 SMART Elongator protein 3 MiaB NifB - - - 3.681e-264 816.0
HKD2_k127_8059590_1 ABC transporter, permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 556.0
HKD2_k127_8059590_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000002742 70.0
HKD2_k127_8059590_4 PFAM Trypsin - - - 0.000007298 50.0
HKD2_k127_8059590_5 addiction module antidote protein HigA K21498 - - 0.0002845 44.0
HKD2_k127_8091019_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 351.0
HKD2_k127_8091019_1 Transposase - - - 0.00000000000001895 80.0
HKD2_k127_8091019_2 Transposase K07494 - - 0.0000000004529 70.0
HKD2_k127_8095040_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 2087.0
HKD2_k127_8095040_1 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 4.683e-306 958.0
HKD2_k127_8095040_10 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 430.0
HKD2_k127_8095040_11 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 409.0
HKD2_k127_8095040_12 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 290.0
HKD2_k127_8095040_13 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000036 259.0
HKD2_k127_8095040_14 retrograde transport, endosome to Golgi K07095 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008081,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0022607,GO:0030145,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000007653 252.0
HKD2_k127_8095040_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000002113 141.0
HKD2_k127_8095040_18 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000002352 128.0
HKD2_k127_8095040_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.993e-254 786.0
HKD2_k127_8095040_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 7.291e-253 782.0
HKD2_k127_8095040_4 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 1.952e-240 746.0
HKD2_k127_8095040_5 diguanylate cyclase - - - 5.792e-229 716.0
HKD2_k127_8095040_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 2.247e-200 628.0
HKD2_k127_8095040_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 548.0
HKD2_k127_8095040_8 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
HKD2_k127_8095040_9 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 479.0
HKD2_k127_8111300_0 - - - - 0.0 1742.0
HKD2_k127_8111300_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1091.0
HKD2_k127_8111300_2 Beta-lactamase superfamily domain - - - 4.948e-232 719.0
HKD2_k127_8111300_3 Iron-containing alcohol dehydrogenase - - - 7.72e-217 677.0
HKD2_k127_8111300_4 drug resistance transporter Bcr CflA subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 609.0
HKD2_k127_8111300_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 482.0
HKD2_k127_8111300_6 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 409.0
HKD2_k127_8111300_7 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001094 252.0
HKD2_k127_8111300_8 Domain of unknown function (DUF1508) - - - 0.00000057 53.0
HKD2_k127_8121515_1 response regulator - - - 1.288e-207 651.0
HKD2_k127_8121515_2 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 470.0
HKD2_k127_8121515_3 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 327.0
HKD2_k127_8121515_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000003841 217.0
HKD2_k127_8121515_6 Belongs to the 5'-nucleotidase family - - - 0.0000000000000000000000000002081 131.0
HKD2_k127_8121515_7 gluconolactonase activity - - - 0.0000000000000002873 89.0
HKD2_k127_8123470_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 9.957e-234 730.0
HKD2_k127_8123470_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 377.0
HKD2_k127_8123470_2 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000000000000000003856 171.0
HKD2_k127_8158804_0 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 557.0
HKD2_k127_8158804_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 440.0
HKD2_k127_8158804_2 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 392.0
HKD2_k127_8158804_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000006752 209.0
HKD2_k127_8158804_4 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000004539 198.0
HKD2_k127_8158804_5 - - - - 0.00000000000000000000000000000000000000000000000001273 182.0
HKD2_k127_8158804_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K01802,K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000006634 164.0
HKD2_k127_8158804_7 Diguanylate cyclase - - - 0.000000000000000000000000017 128.0
HKD2_k127_8158804_9 - - - - 0.00003094 54.0
HKD2_k127_8175604_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 398.0
HKD2_k127_8192810_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000001248 160.0
HKD2_k127_8192810_1 DDE_Tnp_1-associated - - - 0.00000000000001083 81.0
HKD2_k127_8209506_0 PFAM Beta-ketoacyl synthase - - - 0.0 3524.0
HKD2_k127_8209506_1 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.0 2269.0
HKD2_k127_8209506_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 3.404e-304 940.0
HKD2_k127_8209506_11 type IV pilus assembly PilZ - - - 4.688e-295 920.0
HKD2_k127_8209506_12 Sensor histidine kinase, PAS, PAS, PAS and PAS domain-containing - - - 7.297e-266 840.0
HKD2_k127_8209506_13 photoreceptor activity - - - 1.822e-247 775.0
HKD2_k127_8209506_14 TIGRFAM PfaD family protein - - - 5.473e-232 730.0
HKD2_k127_8209506_15 Belongs to the thiolase family K00632 - 2.3.1.16 2.866e-201 632.0
HKD2_k127_8209506_16 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 587.0
HKD2_k127_8209506_17 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 531.0
HKD2_k127_8209506_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 507.0
HKD2_k127_8209506_19 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 484.0
HKD2_k127_8209506_2 Histidine kinase A domain protein - - - 0.0 1587.0
HKD2_k127_8209506_20 PFAM Creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 443.0
HKD2_k127_8209506_21 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 430.0
HKD2_k127_8209506_22 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 413.0
HKD2_k127_8209506_23 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 383.0
HKD2_k127_8209506_24 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 358.0
HKD2_k127_8209506_25 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 353.0
HKD2_k127_8209506_26 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 348.0
HKD2_k127_8209506_27 Histidine kinase K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 346.0
HKD2_k127_8209506_28 fatty acid responsive transcription factor FadR domain protein K03603 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 306.0
HKD2_k127_8209506_29 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 317.0
HKD2_k127_8209506_3 GGDEF domain containing protein - - - 0.0 1287.0
HKD2_k127_8209506_30 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 304.0
HKD2_k127_8209506_31 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 287.0
HKD2_k127_8209506_32 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005865 282.0
HKD2_k127_8209506_33 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006947 280.0
HKD2_k127_8209506_35 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008403 228.0
HKD2_k127_8209506_36 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000007452 229.0
HKD2_k127_8209506_37 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000005269 206.0
HKD2_k127_8209506_38 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000126 198.0
HKD2_k127_8209506_39 PFAM regulatory protein, ArsR - - - 0.0000000000000000000000000000000000000000000000000000008167 193.0
HKD2_k127_8209506_4 Histidine kinase K02482 - 2.7.13.3 0.0 1173.0
HKD2_k127_8209506_40 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000000000000001877 191.0
HKD2_k127_8209506_41 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000002376 168.0
HKD2_k127_8209506_42 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000008879 166.0
HKD2_k127_8209506_43 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000004677 159.0
HKD2_k127_8209506_46 TIGRFAM redox-active disulfide protein 2 - - - 0.000000000000000000000000000000004484 129.0
HKD2_k127_8209506_47 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000001299 144.0
HKD2_k127_8209506_48 - - - - 0.0000000000000000000000007537 104.0
HKD2_k127_8209506_49 Rubrerythrin - - - 0.0000000000000000000003958 96.0
HKD2_k127_8209506_5 FtsX-like permease family K02004 - - 0.0 1154.0
HKD2_k127_8209506_50 - - - - 0.0000000003406 62.0
HKD2_k127_8209506_51 Protein of unknown function DUF134 - - - 0.000002494 52.0
HKD2_k127_8209506_6 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0 1142.0
HKD2_k127_8209506_7 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1075.0
HKD2_k127_8209506_8 Histidine kinase - - - 0.0 1045.0
HKD2_k127_8209506_9 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.187e-308 953.0
HKD2_k127_8230184_0 Transposase and inactivated K07494 - - 0.00000000000000000000000000000000000000000000001935 179.0
HKD2_k127_8230184_1 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.00000000000000000000000003726 112.0
HKD2_k127_8247861_0 pathogenesis K18286,K20276 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 555.0
HKD2_k127_8247861_1 endopeptidase activity - - - 0.00000000000000000000000000000000000000000001028 176.0
HKD2_k127_8255362_0 General secretory system II, protein E domain protein K02652 - - 4.514e-262 810.0
HKD2_k127_8255362_1 Type II secretion system K02455,K02653 - - 2.642e-202 635.0
HKD2_k127_8255362_2 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 412.0
HKD2_k127_8260532_0 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0 1684.0
HKD2_k127_8260532_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1135.0
HKD2_k127_8260532_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 439.0
HKD2_k127_8260532_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 418.0
HKD2_k127_8260532_12 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 401.0
HKD2_k127_8260532_13 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 294.0
HKD2_k127_8260532_14 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 297.0
HKD2_k127_8260532_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 285.0
HKD2_k127_8260532_16 PFAM ATP-binding region, ATPase domain protein K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009168 254.0
HKD2_k127_8260532_17 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.000000000000000000000000000000000000000000000000000000000002312 210.0
HKD2_k127_8260532_18 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000003337 153.0
HKD2_k127_8260532_2 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 2.117e-284 882.0
HKD2_k127_8260532_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 9.571e-271 835.0
HKD2_k127_8260532_4 Tetratricopeptide TPR_2 repeat protein - - - 1.798e-266 831.0
HKD2_k127_8260532_5 AAA domain K07028 - - 2.977e-210 664.0
HKD2_k127_8260532_6 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 557.0
HKD2_k127_8260532_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 563.0
HKD2_k127_8260532_8 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 551.0
HKD2_k127_8260532_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 497.0
HKD2_k127_8274762_0 SMART AAA ATPase K02450 - - 3.7e-225 709.0
HKD2_k127_8274762_1 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 470.0
HKD2_k127_8274762_2 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008315 439.0
HKD2_k127_8274762_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 431.0
HKD2_k127_8274762_4 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 421.0
HKD2_k127_8274762_5 Type II secretion system protein B K02451 - - 0.000000000000000000000000000000000000000000000000005893 190.0
HKD2_k127_8293585_0 Rhodopirellula transposase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
HKD2_k127_8293585_1 Rhodopirellula transposase family protein - - - 0.00000000000000007795 81.0
HKD2_k127_8293585_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000373 80.0
HKD2_k127_83086_0 - - - - 0.0000000000000000000000000000000000000000000000002299 184.0
HKD2_k127_83086_1 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000002492 158.0
HKD2_k127_83086_10 - - - - 0.0006291 42.0
HKD2_k127_83086_3 non supervised orthologous group - - - 0.0000000000000000000000003444 105.0
HKD2_k127_83086_4 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000001015 96.0
HKD2_k127_83086_6 - - - - 0.000000000000000000002415 96.0
HKD2_k127_83086_7 - - - - 0.000000000000000000004142 96.0
HKD2_k127_83086_8 ORF located using Blastx - - - 0.0000000000008448 68.0
HKD2_k127_83086_9 - - - - 0.0000957 46.0
HKD2_k127_8342301_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1074.0
HKD2_k127_8342301_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 4.606e-247 773.0
HKD2_k127_8342301_2 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 1.89e-198 621.0
HKD2_k127_8342301_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 520.0
HKD2_k127_8342301_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 438.0
HKD2_k127_8342301_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008998 243.0
HKD2_k127_8342301_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000000005045 218.0
HKD2_k127_8342301_7 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000000000000000000002907 217.0
HKD2_k127_84180_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1473.0
HKD2_k127_84180_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1427.0
HKD2_k127_84180_10 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 6.563e-242 754.0
HKD2_k127_84180_11 PFAM AAA ATPase central domain protein K07478 - - 9.282e-242 751.0
HKD2_k127_84180_12 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 6.701e-239 749.0
HKD2_k127_84180_13 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.796e-221 688.0
HKD2_k127_84180_14 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 1.321e-209 653.0
HKD2_k127_84180_15 Peptidase U62 modulator of DNA gyrase K03592 - - 4.443e-197 622.0
HKD2_k127_84180_16 Natural resistance-associated macrophage protein K03322 - - 3.821e-195 616.0
HKD2_k127_84180_17 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 609.0
HKD2_k127_84180_18 Alkaline and neutral invertase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 603.0
HKD2_k127_84180_19 PFAM Stage II sporulation K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 589.0
HKD2_k127_84180_2 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1274.0
HKD2_k127_84180_20 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 584.0
HKD2_k127_84180_21 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 561.0
HKD2_k127_84180_22 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823,K12372 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 516.0
HKD2_k127_84180_23 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 504.0
HKD2_k127_84180_24 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 505.0
HKD2_k127_84180_25 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 494.0
HKD2_k127_84180_26 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 480.0
HKD2_k127_84180_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 466.0
HKD2_k127_84180_28 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 462.0
HKD2_k127_84180_29 Nad-dependent epimerase dehydratase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 400.0
HKD2_k127_84180_3 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1206.0
HKD2_k127_84180_30 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 370.0
HKD2_k127_84180_31 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
HKD2_k127_84180_32 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 340.0
HKD2_k127_84180_33 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 307.0
HKD2_k127_84180_34 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 302.0
HKD2_k127_84180_35 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 300.0
HKD2_k127_84180_36 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 284.0
HKD2_k127_84180_37 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 261.0
HKD2_k127_84180_39 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
HKD2_k127_84180_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.0 1049.0
HKD2_k127_84180_40 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000000000000000000000000008556 213.0
HKD2_k127_84180_41 - - - - 0.0000000000000000000000000000000000000000000000000005984 190.0
HKD2_k127_84180_42 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000000000000000000002356 183.0
HKD2_k127_84180_44 PFAM regulatory protein, ArsR - - - 0.00000000000000000000000000000000000000000000009158 169.0
HKD2_k127_84180_45 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000001527 168.0
HKD2_k127_84180_47 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000001016 113.0
HKD2_k127_84180_49 Surface antigen - - - 0.00000000000000000004897 98.0
HKD2_k127_84180_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 8.989e-317 974.0
HKD2_k127_84180_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 3.468e-306 944.0
HKD2_k127_84180_7 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 1.023e-301 937.0
HKD2_k127_84180_8 PFAM phosphoesterase, RecJ domain protein K07462 - - 1.082e-267 833.0
HKD2_k127_84180_9 May be involved in recombinational repair of damaged DNA K03631 - - 2.497e-252 788.0
HKD2_k127_8444506_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1242.0
HKD2_k127_8444506_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1155.0
HKD2_k127_8444506_10 4Fe-4S dicluster domain - - - 4.468e-197 622.0
HKD2_k127_8444506_11 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 582.0
HKD2_k127_8444506_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 560.0
HKD2_k127_8444506_13 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 554.0
HKD2_k127_8444506_14 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 550.0
HKD2_k127_8444506_15 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 525.0
HKD2_k127_8444506_16 PFAM lipopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 501.0
HKD2_k127_8444506_17 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K20276 - 3.4.24.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 496.0
HKD2_k127_8444506_18 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 489.0
HKD2_k127_8444506_19 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 473.0
HKD2_k127_8444506_2 Protein of unknown function, DUF255 K06888 - - 0.0 1039.0
HKD2_k127_8444506_20 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 462.0
HKD2_k127_8444506_21 UDP-N-acetylglucosamine 2-epimerase K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 456.0
HKD2_k127_8444506_22 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 435.0
HKD2_k127_8444506_23 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
HKD2_k127_8444506_24 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 432.0
HKD2_k127_8444506_25 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
HKD2_k127_8444506_26 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 423.0
HKD2_k127_8444506_27 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 391.0
HKD2_k127_8444506_28 cellulose binding K01183,K01233,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.132,3.2.1.14,3.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 402.0
HKD2_k127_8444506_29 cyclic nucleotide binding K10914,K21562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 375.0
HKD2_k127_8444506_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 6.168e-313 970.0
HKD2_k127_8444506_30 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 375.0
HKD2_k127_8444506_31 Type II secretion system (T2SS), protein F K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 352.0
HKD2_k127_8444506_32 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 346.0
HKD2_k127_8444506_33 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 320.0
HKD2_k127_8444506_34 3' exoribonuclease, RNase T-like K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 293.0
HKD2_k127_8444506_35 PFAM Polysaccharide export protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001081 280.0
HKD2_k127_8444506_36 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000002106 263.0
HKD2_k127_8444506_37 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004252 260.0
HKD2_k127_8444506_38 protein tyrosine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
HKD2_k127_8444506_39 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008551 242.0
HKD2_k127_8444506_4 PFAM oxidoreductase - - - 4.877e-263 828.0
HKD2_k127_8444506_40 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000000000000000000000002624 206.0
HKD2_k127_8444506_41 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000000000000009579 194.0
HKD2_k127_8444506_43 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001124 191.0
HKD2_k127_8444506_44 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000001631 190.0
HKD2_k127_8444506_45 membrane K08995 - - 0.000000000000000000000000000000000000000000005155 169.0
HKD2_k127_8444506_46 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000002735 158.0
HKD2_k127_8444506_49 - - - - 0.00000000000000000000000000000008822 132.0
HKD2_k127_8444506_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.944e-240 754.0
HKD2_k127_8444506_50 Outer membrane protein beta-barrel domain K07275 - - 0.0000000000000000000000000000002062 126.0
HKD2_k127_8444506_51 - - - - 0.0000000000000000000000000002018 121.0
HKD2_k127_8444506_52 rubredoxin - - - 0.000000000000000000000000001151 113.0
HKD2_k127_8444506_54 Histidine Phosphotransfer domain - - - 0.000000000000001336 81.0
HKD2_k127_8444506_55 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000001964 59.0
HKD2_k127_8444506_57 TadE-like protein - - - 0.00002396 52.0
HKD2_k127_8444506_6 PFAM type II secretion system protein E K02283,K03609 - - 3.844e-228 712.0
HKD2_k127_8444506_7 Aminotransferase class-V - - - 1.787e-210 657.0
HKD2_k127_8444506_8 Belongs to the peptidase S1C family K04771 - 3.4.21.107 8.665e-201 635.0
HKD2_k127_8444506_9 Pilus formation protein N terminal region K02280 - - 3.454e-199 629.0
HKD2_k127_8465020_0 TIGRFAM cytochrome C family protein - - - 0.00000000002297 73.0
HKD2_k127_8514837_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.575e-309 965.0
HKD2_k127_8514837_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 604.0
HKD2_k127_8514837_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 426.0
HKD2_k127_8514837_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 295.0
HKD2_k127_8514919_0 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 535.0
HKD2_k127_8514919_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 370.0
HKD2_k127_8562967_0 Cys Met metabolism K01739,K01760 - 2.5.1.48,4.4.1.8 1.704e-219 685.0
HKD2_k127_8562967_1 Cys Met metabolism K01760 - 4.4.1.8 1.224e-208 652.0
HKD2_k127_8632_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1554.0
HKD2_k127_8632_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0 1533.0
HKD2_k127_8632_2 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 2.241e-290 896.0
HKD2_k127_8632_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 7.145e-275 857.0
HKD2_k127_8632_4 RmuC family K09760 - - 1.776e-223 703.0
HKD2_k127_8632_5 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 3.343e-213 668.0
HKD2_k127_8632_6 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 484.0
HKD2_k127_8632_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 404.0
HKD2_k127_8632_8 CHRD domain - - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
HKD2_k127_8632_9 CoA carboxylase activity K01965,K17490 - 2.1.3.1,6.4.1.3 0.000000000000000000000000000000000000000000000006489 174.0
HKD2_k127_8658619_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0 1122.0
HKD2_k127_8658619_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0 1062.0
HKD2_k127_8658619_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 463.0
HKD2_k127_8658619_11 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 454.0
HKD2_k127_8658619_12 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 320.0
HKD2_k127_8658619_13 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 259.0
HKD2_k127_8658619_14 PFAM Ribose galactose isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HKD2_k127_8658619_15 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000004141 129.0
HKD2_k127_8658619_16 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000000000000000004712 145.0
HKD2_k127_8658619_17 - - - - 0.0000000000000000002923 90.0
HKD2_k127_8658619_18 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.0000000000003453 86.0
HKD2_k127_8658619_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 4.463e-293 924.0
HKD2_k127_8658619_20 IPT/TIG domain - - - 0.0000002362 66.0
HKD2_k127_8658619_3 4Fe-4S dicluster domain - - - 4.138e-289 901.0
HKD2_k127_8658619_4 Belongs to the ompA family K03286 - - 1.6e-199 632.0
HKD2_k127_8658619_5 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 673.0
HKD2_k127_8658619_6 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 603.0
HKD2_k127_8658619_7 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 596.0
HKD2_k127_8658619_8 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 587.0
HKD2_k127_8658619_9 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 552.0
HKD2_k127_8910461_0 - - - - 1.033e-288 894.0
HKD2_k127_8910461_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000005308 105.0
HKD2_k127_8952728_0 PFAM alpha beta hydrolase fold K22318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 540.0
HKD2_k127_8962733_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 347.0
HKD2_k127_8962733_1 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000009331 215.0
HKD2_k127_8962733_2 PFAM Transposase - - - 0.0000000000000000000000000000000000000000000607 164.0
HKD2_k127_8962733_3 Transposase - - - 0.0000000000000000000000000005297 115.0
HKD2_k127_8962733_4 PFAM Rhodopirellula transposase - - - 0.000000000003094 68.0
HKD2_k127_8962733_5 PFAM Rhodopirellula transposase - - - 0.0000000003672 62.0
HKD2_k127_8965699_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 5.131e-231 723.0
HKD2_k127_8965699_1 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 547.0
HKD2_k127_8965699_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 484.0
HKD2_k127_8965699_4 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 288.0
HKD2_k127_8965699_5 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000001005 86.0
HKD2_k127_8970090_0 AcrB/AcrD/AcrF family - - - 0.0 2304.0
HKD2_k127_8970090_1 Bacterial periplasmic substrate-binding proteins K02030 - - 4.559e-207 660.0
HKD2_k127_8970090_2 Bacterial regulatory protein, Fis family - - - 2.851e-198 638.0
HKD2_k127_8970090_3 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 500.0
HKD2_k127_8970090_4 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 419.0
HKD2_k127_8970090_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005506 262.0
HKD2_k127_8970090_6 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004937 274.0
HKD2_k127_8970090_9 Neutral amino acid transporter - - - 0.0000102 49.0
HKD2_k127_8974969_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000005929 179.0
HKD2_k127_8976291_0 PFAM ThiJ PfpI domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 351.0
HKD2_k127_8976291_1 Outer membrane protein beta-barrel domain K07275 - - 0.0000000000000000000000000000000000000000000000000000000000000004097 225.0
HKD2_k127_8981632_0 ABC transporter, permease protein K02004 - - 4.618e-204 641.0
HKD2_k127_8981632_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 477.0
HKD2_k127_8981863_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 567.0
HKD2_k127_8981863_1 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 337.0
HKD2_k127_8981863_2 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001131 246.0
HKD2_k127_8981863_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000000000000000003352 106.0
HKD2_k127_8981863_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000001301 61.0
HKD2_k127_8983000_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 293.0
HKD2_k127_8983000_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000004171 218.0
HKD2_k127_8994833_0 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 1.121e-278 864.0
HKD2_k127_8994833_1 PFAM glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 6.273e-268 839.0
HKD2_k127_8994833_10 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 371.0
HKD2_k127_8994833_11 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 359.0
HKD2_k127_8994833_12 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 332.0
HKD2_k127_8994833_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 327.0
HKD2_k127_8994833_14 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 318.0
HKD2_k127_8994833_16 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 295.0
HKD2_k127_8994833_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 291.0
HKD2_k127_8994833_18 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 290.0
HKD2_k127_8994833_19 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000003415 237.0
HKD2_k127_8994833_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.651e-248 773.0
HKD2_k127_8994833_20 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000000001355 218.0
HKD2_k127_8994833_21 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000003101 196.0
HKD2_k127_8994833_22 - - - - 0.00000000000000000000000000000000000000000000000001041 181.0
HKD2_k127_8994833_23 - - - - 0.0000000000000000000000000000000000000000005382 160.0
HKD2_k127_8994833_3 Belongs to the ALAD family K01698 - 4.2.1.24 7.306e-210 654.0
HKD2_k127_8994833_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 606.0
HKD2_k127_8994833_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 577.0
HKD2_k127_8994833_6 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 552.0
HKD2_k127_8994833_7 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 494.0
HKD2_k127_8994833_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 469.0
HKD2_k127_8994833_9 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 445.0
HKD2_k127_8996635_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0 1049.0
HKD2_k127_8996635_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 1.765e-241 756.0
HKD2_k127_8996635_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000009711 147.0
HKD2_k127_8996635_11 TM2 domain - - - 0.0000000000000000000000000000000003951 138.0
HKD2_k127_8996635_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 5.819e-203 634.0
HKD2_k127_8996635_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 7.873e-199 629.0
HKD2_k127_8996635_4 PFAM tRNA synthetase, class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 480.0
HKD2_k127_8996635_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 370.0
HKD2_k127_8996635_6 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000263 246.0
HKD2_k127_8996635_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000601 228.0
HKD2_k127_8996635_8 Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000003412 177.0
HKD2_k127_8996635_9 - - - - 0.0000000000000000000000000000000000000000000005166 177.0
HKD2_k127_8999243_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 420.0
HKD2_k127_8999243_1 PFAM Lipid A 3-O-deacylase-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000258 229.0
HKD2_k127_8999243_2 - - - - 0.0000000000000000000000000000001068 129.0
HKD2_k127_8999370_0 histidine kinase HAMP region domain protein K03406 - - 7.502e-295 921.0
HKD2_k127_8999370_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 453.0
HKD2_k127_9005631_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.657e-304 941.0
HKD2_k127_9005631_1 TIGRFAM YidE YbjL duplication K07085 - - 2.956e-243 757.0
HKD2_k127_9005631_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 446.0
HKD2_k127_9005631_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 354.0
HKD2_k127_9005631_4 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000003064 220.0
HKD2_k127_9005631_5 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000732 101.0
HKD2_k127_9007729_0 PFAM Extracellular solute-binding protein, family 3 - - - 1.247e-254 797.0
HKD2_k127_9007729_1 response regulator - - - 4.901e-238 745.0
HKD2_k127_9007729_2 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07792 - - 1.184e-194 614.0
HKD2_k127_9007729_3 SH3 domain (SH3b1 type) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009927 266.0
HKD2_k127_9009197_0 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 4.01e-212 668.0
HKD2_k127_9009197_1 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 375.0
HKD2_k127_9012081_0 Asparagine synthase K01953 - 6.3.5.4 4.531e-211 674.0
HKD2_k127_9012081_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 397.0
HKD2_k127_9012081_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 372.0
HKD2_k127_9014119_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1038.0
HKD2_k127_9014119_1 Response regulator, receiver - - - 5.643e-293 916.0
HKD2_k127_9014119_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005187 238.0
HKD2_k127_9014119_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000001089 232.0
HKD2_k127_9014119_12 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000007707 202.0
HKD2_k127_9014119_13 CDP-diacylglycerol pyrophosphatase K01521 - 3.6.1.26 0.00000000000000000000000000000000000000000000000000002989 197.0
HKD2_k127_9014119_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 7.132e-223 692.0
HKD2_k127_9014119_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 9.373e-222 689.0
HKD2_k127_9014119_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 8.677e-203 633.0
HKD2_k127_9014119_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 7.806e-202 630.0
HKD2_k127_9014119_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 560.0
HKD2_k127_9014119_7 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 451.0
HKD2_k127_9014119_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 366.0
HKD2_k127_9014119_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009213 269.0
HKD2_k127_9017183_0 Histidine kinase K02482 - 2.7.13.3 3.452e-272 848.0
HKD2_k127_9017183_1 response regulator K02481 - - 8.652e-253 788.0
HKD2_k127_9017183_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 500.0
HKD2_k127_9017183_11 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 471.0
HKD2_k127_9017183_12 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002426 263.0
HKD2_k127_9017183_13 PFAM nuclease (SNase domain protein) K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002181 261.0
HKD2_k127_9017183_14 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000004921 240.0
HKD2_k127_9017183_15 SMART Mov34 MPN PAD-1 family protein K21140 - 3.13.1.6 0.0000000000000000000000000001594 115.0
HKD2_k127_9017183_16 TIGRFAM thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000000000000002222 112.0
HKD2_k127_9017183_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 2.905e-222 695.0
HKD2_k127_9017183_3 Iron-containing alcohol dehydrogenase K00086 - 1.1.1.202 1.924e-207 649.0
HKD2_k127_9017183_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 580.0
HKD2_k127_9017183_5 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 577.0
HKD2_k127_9017183_6 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 561.0
HKD2_k127_9017183_7 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 489.0
HKD2_k127_9017183_8 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 494.0
HKD2_k127_9017183_9 Binding-protein-dependent transport system inner membrane component K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 479.0
HKD2_k127_9041936_0 gluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 508.0
HKD2_k127_9041936_1 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000003321 156.0
HKD2_k127_9041936_2 Metallo-peptidase family M12 - - - 0.0000001626 53.0
HKD2_k127_9062568_0 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000034 159.0
HKD2_k127_9062568_1 O-methyltransferase activity - - - 0.000000005478 61.0
HKD2_k127_9071702_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.981e-254 796.0
HKD2_k127_9071702_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 529.0
HKD2_k127_9071702_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 501.0
HKD2_k127_9071702_3 PFAM transport-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 460.0
HKD2_k127_9071702_4 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 454.0
HKD2_k127_9071702_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 358.0
HKD2_k127_9071702_6 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 332.0
HKD2_k127_9071702_7 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
HKD2_k127_9075871_0 Sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 426.0
HKD2_k127_9075871_1 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001701 189.0
HKD2_k127_9075871_2 - - - - 0.00004956 48.0
HKD2_k127_9075871_3 - - - - 0.00008963 47.0
HKD2_k127_9082150_0 transposition - - - 1.078e-227 710.0
HKD2_k127_9082150_1 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001998 240.0
HKD2_k127_9088248_0 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0 1068.0
HKD2_k127_9088248_1 PFAM magnesium chelatase ChlI subunit K07391 - - 1.421e-300 925.0
HKD2_k127_9088248_10 - - - - 0.00000000000000000000000000000000000000000000000000000008163 197.0
HKD2_k127_9088248_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 2.745e-228 710.0
HKD2_k127_9088248_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 565.0
HKD2_k127_9088248_4 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 547.0
HKD2_k127_9088248_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 527.0
HKD2_k127_9088248_6 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 484.0
HKD2_k127_9088248_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 420.0
HKD2_k127_9088248_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 357.0
HKD2_k127_9088248_9 Guanylyl transferase CofC like K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009823 269.0
HKD2_k127_9113399_0 Peptidase family M23 - - - 5.398e-199 628.0
HKD2_k127_9113399_2 Transglycosylase K21464 - 2.4.1.129,3.4.16.4 0.00000000001711 66.0
HKD2_k127_9128196_0 COG3666 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000004354 192.0
HKD2_k127_9147510_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 485.0
HKD2_k127_9147510_1 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002429 258.0
HKD2_k127_9147510_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000001219 186.0
HKD2_k127_9152346_0 acetyl-CoA hydrolase transferase K18288 - - 5.119e-228 709.0
HKD2_k127_9152346_1 - - - - 4.111e-221 692.0
HKD2_k127_9152346_2 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 402.0
HKD2_k127_9152346_3 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 347.0
HKD2_k127_9152346_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 319.0
HKD2_k127_9152346_5 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 284.0
HKD2_k127_9209668_0 histidine kinase HAMP region domain protein K03406 - - 5.228e-272 846.0
HKD2_k127_9209668_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 584.0
HKD2_k127_9209668_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 370.0
HKD2_k127_9209668_3 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001111 250.0
HKD2_k127_9209668_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000009133 208.0
HKD2_k127_9233917_0 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 391.0
HKD2_k127_9233917_1 PFAM transposase IS3 IS911 family protein K07497 - - 0.000000000000000000000000009148 111.0
HKD2_k127_9237636_0 Protein export membrane protein K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 287.0
HKD2_k127_9237636_1 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000000000000000000000000000000000000001684 217.0
HKD2_k127_9259556_0 PFAM Transposase DDE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 359.0
HKD2_k127_9266930_0 Site-specific recombinase, DNA invertase Pin - - - 5.812e-260 820.0
HKD2_k127_9266930_1 IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000007752 160.0
HKD2_k127_9266930_2 Integrase core domain - - - 0.00002534 52.0
HKD2_k127_9275253_0 MMPL family K07003 - - 0.0 1305.0
HKD2_k127_9275253_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.0 1240.0
HKD2_k127_9275253_10 rRNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 308.0
HKD2_k127_9275253_11 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001588 268.0
HKD2_k127_9275253_12 PFAM NLP P60 protein K19223 - - 0.00000000000000000000000000000000000000000000000000000000000000001273 233.0
HKD2_k127_9275253_13 hmm pf00545 - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000241 209.0
HKD2_k127_9275253_14 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000001452 162.0
HKD2_k127_9275253_15 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000008422 154.0
HKD2_k127_9275253_16 Barstar (barnase inhibitor) K03623 - - 0.0000000000000000000000000000000001542 134.0
HKD2_k127_9275253_17 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000004591 151.0
HKD2_k127_9275253_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1077.0
HKD2_k127_9275253_20 Protein of unknown function (DUF2905) - - - 0.000000000000000000000000000007233 119.0
HKD2_k127_9275253_21 Helix-turn-helix XRE-family like proteins K15773 - - 0.0000000000000000000000000002408 115.0
HKD2_k127_9275253_22 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000002359 113.0
HKD2_k127_9275253_23 PilZ domain - - - 0.00000000000000000000001502 106.0
HKD2_k127_9275253_24 - - - - 0.000004824 53.0
HKD2_k127_9275253_26 COG0457 FOG TPR repeat - - - 0.0006734 51.0
HKD2_k127_9275253_3 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 2.723e-214 666.0
HKD2_k127_9275253_4 Pfam:HipA_N K07154 - 2.7.11.1 1.404e-207 652.0
HKD2_k127_9275253_5 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 9.123e-195 612.0
HKD2_k127_9275253_6 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 630.0
HKD2_k127_9275253_7 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 552.0
HKD2_k127_9275253_8 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 347.0
HKD2_k127_9275253_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 310.0
HKD2_k127_9286542_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 548.0
HKD2_k127_9328179_0 COG1484 DNA replication protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 289.0
HKD2_k127_9328179_1 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000653 274.0
HKD2_k127_933080_0 Flagellar biogenesis master sigma-54-dependent transcriptional response regulator - - - 2.261e-209 662.0
HKD2_k127_933080_1 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 458.0
HKD2_k127_933080_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001375 252.0
HKD2_k127_933080_3 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000001436 128.0
HKD2_k127_933080_6 PFAM ThiJ PfpI domain protein - - - 0.000000001435 59.0
HKD2_k127_933080_7 - - - - 0.00000009516 54.0
HKD2_k127_9350585_0 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001099 283.0
HKD2_k127_9375030_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 347.0
HKD2_k127_9375030_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 312.0
HKD2_k127_9375030_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000211 221.0
HKD2_k127_9375030_3 Phosphopantetheine attachment site K02078 - - 0.000000000000000000002741 96.0
HKD2_k127_9375030_4 lipid A biosynthesis acyltransferase - - - 0.00000002666 55.0
HKD2_k127_9379247_0 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 488.0
HKD2_k127_9390185_0 - - - - 0.00000000000000000000000004056 119.0
HKD2_k127_9390185_1 - - - - 0.0000004534 57.0
HKD2_k127_9394278_0 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 390.0
HKD2_k127_9394278_1 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007614 278.0
HKD2_k127_9447536_0 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.0 1123.0
HKD2_k127_9447536_1 Domains REC, sigma54 interaction, HTH8 - - - 2.426e-266 824.0
HKD2_k127_9447536_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 547.0
HKD2_k127_9447536_3 Conserved protein K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 459.0
HKD2_k127_9453517_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 380.0
HKD2_k127_9462652_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 466.0
HKD2_k127_9462652_1 - - - - 0.0000000000000000000000000000009574 124.0
HKD2_k127_9462652_2 - - - - 0.0000000000001918 73.0
HKD2_k127_9462811_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 299.0
HKD2_k127_949280_0 type I restriction modification DNA specificity domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 365.0
HKD2_k127_949280_1 Helicase conserved C-terminal domain - - - 0.0000000000000002649 83.0
HKD2_k127_9551390_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 377.0
HKD2_k127_9551390_1 Shikimate quinate 5-dehydrogenase family protein K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 312.0
HKD2_k127_9551390_2 LrgB-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 294.0
HKD2_k127_9551390_3 LrgA family K06518 - - 0.000000000000000000000000000000000009509 141.0
HKD2_k127_9577089_0 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 361.0
HKD2_k127_9577089_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000135 143.0
HKD2_k127_9577089_2 - - - - 0.0000000000001925 79.0
HKD2_k127_9577089_3 LrgB-like family - - - 0.000000002863 58.0
HKD2_k127_9577158_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1993.0
HKD2_k127_9577158_1 4Fe-4S dicluster domain - - - 0.0 1231.0
HKD2_k127_9577158_10 acyl-coa dehydrogenase - - - 6.927e-215 675.0
HKD2_k127_9577158_11 Belongs to the thiolase family K00626 - 2.3.1.9 4.619e-214 670.0
HKD2_k127_9577158_12 electron transfer flavoprotein, alpha subunit K03522 - - 1.108e-211 665.0
HKD2_k127_9577158_13 PFAM Coenzyme A transferase K01039 - 2.8.3.12 8.705e-202 629.0
HKD2_k127_9577158_14 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 613.0
HKD2_k127_9577158_15 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 585.0
HKD2_k127_9577158_16 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 531.0
HKD2_k127_9577158_17 PFAM Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 526.0
HKD2_k127_9577158_18 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 520.0
HKD2_k127_9577158_19 Chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 529.0
HKD2_k127_9577158_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1078.0
HKD2_k127_9577158_20 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 454.0
HKD2_k127_9577158_21 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 453.0
HKD2_k127_9577158_22 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 451.0
HKD2_k127_9577158_23 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 471.0
HKD2_k127_9577158_24 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 417.0
HKD2_k127_9577158_25 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 374.0
HKD2_k127_9577158_26 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 364.0
HKD2_k127_9577158_27 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 350.0
HKD2_k127_9577158_28 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 300.0
HKD2_k127_9577158_29 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 303.0
HKD2_k127_9577158_3 PFAM Acetyl-CoA hydrolase transferase K01067,K18118 - 2.8.3.18,3.1.2.1 3.7e-322 988.0
HKD2_k127_9577158_31 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009977 284.0
HKD2_k127_9577158_32 Transcription regulator MerR DNA binding K21902 - - 0.00000000000000000000000000000000000000000000000000000000000000001623 226.0
HKD2_k127_9577158_33 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000000000000005432 182.0
HKD2_k127_9577158_34 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000000000000000009762 180.0
HKD2_k127_9577158_35 PFAM Protein phosphatase K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000002327 178.0
HKD2_k127_9577158_36 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000003563 188.0
HKD2_k127_9577158_37 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000002313 89.0
HKD2_k127_9577158_38 - - - - 0.000000000000003391 85.0
HKD2_k127_9577158_39 Fn3 associated - - - 0.00000000000002486 87.0
HKD2_k127_9577158_4 4Fe-4S dicluster domain - - - 2.498e-300 932.0
HKD2_k127_9577158_40 PFAM PKD domain containing protein - - - 0.0000000000009034 82.0
HKD2_k127_9577158_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.057e-293 907.0
HKD2_k127_9577158_6 PFAM Extracellular solute-binding protein, family 3 K02030 - - 3.824e-253 794.0
HKD2_k127_9577158_7 Sigma-54 factor interaction domain-containing protein - - - 2.083e-238 747.0
HKD2_k127_9577158_8 acyl-coa dehydrogenase K00248 - 1.3.8.1 8.583e-227 704.0
HKD2_k127_9577158_9 Bacterial regulatory protein, Fis family - - - 7.263e-224 700.0
HKD2_k127_9616473_0 PFAM biotin lipoyl attachment domain-containing protein - - - 0.0 1745.0
HKD2_k127_9616473_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1434.0
HKD2_k127_9616473_10 Tetratricopeptide TPR_2 repeat protein - - - 1.558e-291 911.0
HKD2_k127_9616473_11 SMART PAS domain containing protein - - - 2.223e-287 899.0
HKD2_k127_9616473_12 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 5.376e-287 886.0
HKD2_k127_9616473_13 DHHA2 domain protein K15986 - 3.6.1.1 4.537e-283 877.0
HKD2_k127_9616473_14 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 1.726e-275 850.0
HKD2_k127_9616473_15 Cytochrome c554 and c-prime - - - 1.182e-274 852.0
HKD2_k127_9616473_16 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 6.146e-264 824.0
HKD2_k127_9616473_17 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.285e-257 796.0
HKD2_k127_9616473_18 4Fe-4S dicluster domain K11473 - - 2.799e-253 785.0
HKD2_k127_9616473_19 UvrD-like helicase C-terminal domain - - - 3.567e-238 752.0
HKD2_k127_9616473_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1322.0
HKD2_k127_9616473_20 Domain of unknown function (DUF2088) - - - 4.227e-224 699.0
HKD2_k127_9616473_21 PFAM penicillin-binding protein transpeptidase - - - 8.829e-216 676.0
HKD2_k127_9616473_22 TIGRFAM branched-chain amino acid aminotransferase K00826 - 2.6.1.42 1.116e-208 652.0
HKD2_k127_9616473_23 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 1.115e-196 622.0
HKD2_k127_9616473_24 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 602.0
HKD2_k127_9616473_25 PFAM ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 591.0
HKD2_k127_9616473_27 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 503.0
HKD2_k127_9616473_28 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 491.0
HKD2_k127_9616473_29 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 484.0
HKD2_k127_9616473_3 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0 1198.0
HKD2_k127_9616473_30 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 481.0
HKD2_k127_9616473_31 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 467.0
HKD2_k127_9616473_32 Cell surface protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 462.0
HKD2_k127_9616473_33 SMART PDZ DHR GLGF domain protein K02452 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 441.0
HKD2_k127_9616473_34 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 426.0
HKD2_k127_9616473_35 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007841 416.0
HKD2_k127_9616473_36 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 419.0
HKD2_k127_9616473_37 Calcineurin-like phosphoesterase K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 410.0
HKD2_k127_9616473_38 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 414.0
HKD2_k127_9616473_39 Pfam:UPF0118 K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 401.0
HKD2_k127_9616473_4 PFAM carboxyl transferase - - - 0.0 1093.0
HKD2_k127_9616473_40 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 397.0
HKD2_k127_9616473_41 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 381.0
HKD2_k127_9616473_42 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 359.0
HKD2_k127_9616473_43 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 338.0
HKD2_k127_9616473_44 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 317.0
HKD2_k127_9616473_45 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 288.0
HKD2_k127_9616473_46 Type II secretion system (T2SS), protein J K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002584 278.0
HKD2_k127_9616473_48 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 260.0
HKD2_k127_9616473_49 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009414 248.0
HKD2_k127_9616473_5 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.826e-321 987.0
HKD2_k127_9616473_50 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003495 239.0
HKD2_k127_9616473_51 Uncharacterised protein family (UPF0158) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006658 239.0
HKD2_k127_9616473_52 TIGRFAM general secretion pathway protein F K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000004199 243.0
HKD2_k127_9616473_53 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000007509 224.0
HKD2_k127_9616473_54 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000000000000000000000000000000000000000000000005991 224.0
HKD2_k127_9616473_55 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000001895 223.0
HKD2_k127_9616473_56 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000005038 220.0
HKD2_k127_9616473_57 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000001141 199.0
HKD2_k127_9616473_58 PFAM Methylamine - - - 0.000000000000000000000000000000000000000000000000003863 186.0
HKD2_k127_9616473_59 gas vesicle protein - - - 0.0000000000000000000000000000000000000000000000005494 176.0
HKD2_k127_9616473_6 PFAM Type II secretion system protein E K02454 - - 9.279e-313 961.0
HKD2_k127_9616473_60 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000004435 177.0
HKD2_k127_9616473_61 Bacterial protein of unknown function (DUF948) - - - 0.0000000000000000000000000000000000000000000003295 169.0
HKD2_k127_9616473_66 metal cluster binding K06940 - - 0.000000000000000000000000000000002706 133.0
HKD2_k127_9616473_68 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000000000001433 122.0
HKD2_k127_9616473_69 YHS domain - - - 0.0000000000000000000000000000461 117.0
HKD2_k127_9616473_7 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 9.19e-306 949.0
HKD2_k127_9616473_71 regulation of response to stimulus K02014,K13730 - - 0.00000000000000005563 95.0
HKD2_k127_9616473_72 Chagasin family peptidase inhibitor I42 - - - 0.000000000000008255 85.0
HKD2_k127_9616473_75 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.000000000821 62.0
HKD2_k127_9616473_76 - - - - 0.000001259 60.0
HKD2_k127_9616473_77 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000001342 61.0
HKD2_k127_9616473_79 hydrolase family 81 - - - 0.0001492 55.0
HKD2_k127_9616473_8 Type II and III secretion system protein K02453 - - 3.749e-303 940.0
HKD2_k127_9616473_80 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0003668 51.0
HKD2_k127_9616473_9 Protein of unknown function (DUF3373) - - - 1.525e-291 902.0
HKD2_k127_9671734_1 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000002539 119.0
HKD2_k127_9696897_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.72e-266 822.0
HKD2_k127_9696897_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 603.0
HKD2_k127_9696897_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 552.0
HKD2_k127_9696897_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 497.0
HKD2_k127_9696897_4 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 359.0
HKD2_k127_9696897_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 345.0
HKD2_k127_9696897_6 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001485 278.0
HKD2_k127_9696897_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000421 260.0
HKD2_k127_9696897_8 chemotaxis K03410 - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
HKD2_k127_9709045_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 453.0
HKD2_k127_9709045_1 Transposase and inactivated derivatives K07497 - - 0.00001655 49.0
HKD2_k127_9721827_0 12 heme-binding sites - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001231 264.0
HKD2_k127_9721827_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004122 261.0
HKD2_k127_9721827_2 COG0671 Membrane-associated phospholipid phosphatase - GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009605,GO:0009607,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0042578,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0046467,GO:0046493,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0071704,GO:0075136,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000006317 247.0
HKD2_k127_979646_0 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 2.167e-212 714.0
HKD2_k127_979646_1 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000324 210.0
HKD2_k127_9822691_0 hmm pf01520 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000001758 161.0
HKD2_k127_9822691_2 - - - - 0.00000000000000000000001911 102.0
HKD2_k127_9822691_3 - - - - 0.0001053 55.0
HKD2_k127_9825269_0 - - - - 0.0000000000000000000000000000001704 125.0
HKD2_k127_9825269_1 - - - - 0.0000000000000000000000008919 104.0
HKD2_k127_9825269_2 mitotic sister chromatid biorientation - - - 0.0000000000000000001672 91.0
HKD2_k127_9825269_3 - - - - 0.00000000000000007578 87.0
HKD2_k127_9825269_4 - - - - 0.000000000000007241 79.0
HKD2_k127_9863300_0 Protein kinase, ABC1 domain-containing - - - 6.733e-240 749.0
HKD2_k127_9863300_1 Phage tail sheath C-terminal domain K06907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 578.0
HKD2_k127_9863300_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 437.0
HKD2_k127_9863300_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 338.0
HKD2_k127_9863300_4 transcriptional regulator K22108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 318.0
HKD2_k127_9863300_5 Protein of unknown function (DUF4255) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 293.0
HKD2_k127_9863300_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002175 268.0
HKD2_k127_9863300_7 - - - - 0.00000000000000000569 85.0
HKD2_k127_9880591_0 PFAM Multi antimicrobial extrusion protein MatE K03327 - - 7.005e-210 662.0
HKD2_k127_9880591_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 547.0
HKD2_k127_9880591_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 323.0
HKD2_k127_9880591_3 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000003232 183.0
HKD2_k127_9880591_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000004202 124.0
HKD2_k127_9880591_6 - - - - 0.0000000000001547 70.0
HKD2_k127_9896654_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 0.0000000000000000000000000000000000000000000002529 168.0
HKD2_k127_9963073_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.48e-321 997.0
HKD2_k127_9963073_1 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000174 246.0
HKD2_k127_9963073_2 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000000001159 168.0