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Overview

ID MAG01780
Name HKD2_bin.20
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Vicinamibacteria
Order Fen-336
Family Fen-336
Genus DATKME01
Species
Assembly information
Completeness (%) 63.42
Contamination (%) 1.75
GC content (%) 73.0
N50 (bp) 14,743
Genome size (bp) 3,261,068

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2665

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10030085_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 450.0
HKD2_k127_10030085_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 409.0
HKD2_k127_10030085_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000005513 217.0
HKD2_k127_10030085_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000007746 127.0
HKD2_k127_10030085_4 Thioesterase superfamily - - - 0.000000000000000000000000000001995 128.0
HKD2_k127_10030085_5 Tetratricopeptide repeat - - - 0.0000000000000000000001134 106.0
HKD2_k127_10030085_6 metal cluster binding K06940 - - 0.00000000000004347 81.0
HKD2_k127_10030519_0 cellulose binding - - - 7.817e-268 848.0
HKD2_k127_10030519_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 388.0
HKD2_k127_10030519_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 308.0
HKD2_k127_10030519_3 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003316 289.0
HKD2_k127_10030519_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001172 255.0
HKD2_k127_10030519_5 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000000000000000000001647 248.0
HKD2_k127_10030519_6 Domain of unknown function (DUF4962) K19051 GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510 4.2.2.7,4.2.2.8 0.0000000000000000000000000000000000000000000001491 193.0
HKD2_k127_10030519_7 - K03646 - - 0.0000000695 64.0
HKD2_k127_10077228_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 561.0
HKD2_k127_10077228_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 415.0
HKD2_k127_10077228_2 COGs COG2912 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000293 241.0
HKD2_k127_10077228_3 DNA-binding transcription factor activity - - - 0.000000000000000000000131 102.0
HKD2_k127_10077228_4 Outer membrane efflux protein - - - 0.00000000000000000007196 103.0
HKD2_k127_10087930_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1696.0
HKD2_k127_10087930_1 Phosphoesterase family - - - 1.651e-209 684.0
HKD2_k127_10087930_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 400.0
HKD2_k127_10087930_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009087 269.0
HKD2_k127_10095344_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008627 301.0
HKD2_k127_10095344_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 259.0
HKD2_k127_10095344_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000003326 247.0
HKD2_k127_10095344_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000001231 184.0
HKD2_k127_10095344_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.7.7.7 0.00000000000000000000000000000000000000000002051 175.0
HKD2_k127_10095344_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000002854 158.0
HKD2_k127_10095344_6 - - - - 0.000000000000000000000000000001121 141.0
HKD2_k127_10095344_7 lyase activity - - - 0.00000000005449 75.0
HKD2_k127_10095344_8 Protein of unknown function (DUF3467) - - - 0.000003364 53.0
HKD2_k127_10117754_0 Glycoside hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 507.0
HKD2_k127_10117754_1 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 464.0
HKD2_k127_10117754_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 438.0
HKD2_k127_10117754_3 RarD protein K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006443 285.0
HKD2_k127_10117754_4 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000003236 173.0
HKD2_k127_10117754_5 - - - - 0.0000000000000000000000000000007002 130.0
HKD2_k127_10117754_6 - - - - 0.000000000000000000000000000002356 132.0
HKD2_k127_10117754_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000004044 88.0
HKD2_k127_10141269_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 3.968e-247 787.0
HKD2_k127_10141269_1 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 617.0
HKD2_k127_10141269_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 299.0
HKD2_k127_1067726_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.000000000000000000000000000000000000000000000000000007325 201.0
HKD2_k127_1067726_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000006673 124.0
HKD2_k127_1067726_2 Zn peptidase - - - 0.000000000000000000000000000009194 138.0
HKD2_k127_1067726_3 Mitochondrial biogenesis AIM24 - - - 0.000000000000002157 89.0
HKD2_k127_1067726_4 Domain of unknown function (DUF4870) - - - 0.00000000001637 78.0
HKD2_k127_1067726_5 radical SAM domain protein K22226 - - 0.0000162 57.0
HKD2_k127_1099893_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.229e-288 905.0
HKD2_k127_1099893_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000001858 258.0
HKD2_k127_1099893_2 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000001967 179.0
HKD2_k127_1099893_3 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000001452 162.0
HKD2_k127_1099893_4 B12 binding domain - - - 0.000000000000000000000000000004988 137.0
HKD2_k127_1099893_5 Amidohydrolase family - - - 0.00000000000000000000000000004442 135.0
HKD2_k127_1099893_6 GAF domain - - - 0.0000000000000003341 85.0
HKD2_k127_1099893_7 Polysaccharide biosynthesis protein - - - 0.000808 52.0
HKD2_k127_1106155_0 AAA-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 522.0
HKD2_k127_1106155_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 376.0
HKD2_k127_1106155_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000007986 193.0
HKD2_k127_1109326_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0 1129.0
HKD2_k127_1109326_1 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 2.587e-220 687.0
HKD2_k127_1109326_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406,K01011,K07112 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000002483 214.0
HKD2_k127_1109326_11 PFAM OsmC family protein K09136 - - 0.0000000000000000000000000000000000000000001995 162.0
HKD2_k127_1109326_12 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.0000000000000000000000000000000000000000007153 168.0
HKD2_k127_1109326_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000009714 153.0
HKD2_k127_1109326_14 Histidine kinase - - - 0.00000000000000000000000276 118.0
HKD2_k127_1109326_15 - - - - 0.0000000003225 70.0
HKD2_k127_1109326_16 of the alpha beta superfamily - - - 0.000005074 57.0
HKD2_k127_1109326_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 525.0
HKD2_k127_1109326_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 445.0
HKD2_k127_1109326_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 418.0
HKD2_k127_1109326_5 PFAM virulence factor family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 417.0
HKD2_k127_1109326_6 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 312.0
HKD2_k127_1109326_7 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 307.0
HKD2_k127_1109326_8 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000000886 239.0
HKD2_k127_1109326_9 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000009133 208.0
HKD2_k127_1120819_0 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 447.0
HKD2_k127_1120819_1 saccharopine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 359.0
HKD2_k127_1120819_2 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 358.0
HKD2_k127_1120819_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000002094 238.0
HKD2_k127_1120819_4 - - - - 0.000000000000000000000000000000000000000001521 172.0
HKD2_k127_1120819_5 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000006754 141.0
HKD2_k127_1120819_6 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.00000000000000000000000000000001129 132.0
HKD2_k127_1120819_7 P-loop containing region of AAA domain K03546 - - 0.0000000000000000000000000000003241 125.0
HKD2_k127_1120819_8 BON domain - - - 0.000000000000007466 78.0
HKD2_k127_1120819_9 Xanthine dehydrogenase K12528 GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00001725 53.0
HKD2_k127_1181365_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 352.0
HKD2_k127_1181365_1 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001287 309.0
HKD2_k127_1181365_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000004827 171.0
HKD2_k127_1299459_0 PIN domain K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 516.0
HKD2_k127_1299459_1 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 394.0
HKD2_k127_1299459_2 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002383 256.0
HKD2_k127_1299459_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000002609 222.0
HKD2_k127_1299459_4 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000001708 87.0
HKD2_k127_1333255_0 Mur ligase middle domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 421.0
HKD2_k127_1333255_1 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000001389 233.0
HKD2_k127_1333255_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000122 50.0
HKD2_k127_1342215_0 Fibronectin type III-like domain K05349 - 3.2.1.21 1.626e-253 806.0
HKD2_k127_1342215_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 9.512e-195 617.0
HKD2_k127_1342215_10 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000008401 234.0
HKD2_k127_1342215_11 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000004983 226.0
HKD2_k127_1342215_12 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000001135 224.0
HKD2_k127_1342215_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000002193 202.0
HKD2_k127_1342215_14 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000003851 188.0
HKD2_k127_1342215_15 PFAM Diacylglycerol kinase, catalytic - - - 0.0000000000000000000000000000000000000000000003038 183.0
HKD2_k127_1342215_16 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000001987 167.0
HKD2_k127_1342215_17 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000001138 124.0
HKD2_k127_1342215_18 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000007341 114.0
HKD2_k127_1342215_19 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000000000914 94.0
HKD2_k127_1342215_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 412.0
HKD2_k127_1342215_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.0000000000000001278 83.0
HKD2_k127_1342215_3 transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 335.0
HKD2_k127_1342215_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 300.0
HKD2_k127_1342215_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 289.0
HKD2_k127_1342215_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009058 283.0
HKD2_k127_1342215_7 Thermolysin metallopeptidase, alpha-helical domain K01400 GO:0005575,GO:0005576 3.4.24.28 0.0000000000000000000000000000000000000000000000000000000000000000000000002202 270.0
HKD2_k127_1342215_8 Belongs to the DapA family K01714,K22397 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0047440,GO:0071704,GO:0072329,GO:1901575 4.1.2.28,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000005034 263.0
HKD2_k127_1342215_9 Protein serine threonine phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000003117 233.0
HKD2_k127_1346491_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 563.0
HKD2_k127_1346491_1 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 376.0
HKD2_k127_1346491_2 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 333.0
HKD2_k127_1346491_3 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000113 198.0
HKD2_k127_1346491_4 FeS assembly SUF system protein SufT - - - 0.000000000000000000000000000000000000000000000000000001577 197.0
HKD2_k127_1346491_5 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000001523 205.0
HKD2_k127_1346491_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000008224 164.0
HKD2_k127_1346491_7 biosynthesis protein K08253 - 2.7.10.2 0.000000000000000000000006598 115.0
HKD2_k127_1346491_8 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000008879 93.0
HKD2_k127_1346491_9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07669 - - 0.00000000000002127 86.0
HKD2_k127_1347651_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 4.14e-280 889.0
HKD2_k127_1347651_1 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 593.0
HKD2_k127_1347651_10 permease K07243 - - 0.00000000000000007471 87.0
HKD2_k127_1347651_11 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0002837 54.0
HKD2_k127_1347651_2 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 505.0
HKD2_k127_1347651_3 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 383.0
HKD2_k127_1347651_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 321.0
HKD2_k127_1347651_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000231 224.0
HKD2_k127_1347651_6 Domain of unknown function (DUF4405) - - - 0.00000000000000000000000000000000000000000000000000000154 210.0
HKD2_k127_1347651_7 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.00000000000000000000000000000000009679 141.0
HKD2_k127_1347651_8 HupF/HypC family K04653 - - 0.000000000000000000000000000393 115.0
HKD2_k127_1347651_9 nickel cation binding K04651 - - 0.00000000000000000000000002626 118.0
HKD2_k127_1352680_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1297.0
HKD2_k127_1352680_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 395.0
HKD2_k127_1352680_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 349.0
HKD2_k127_1352680_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 342.0
HKD2_k127_1352680_4 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 298.0
HKD2_k127_1352680_5 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000007339 171.0
HKD2_k127_1352680_6 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000000000000000000000000000004259 162.0
HKD2_k127_1352680_7 VIT family - - - 0.000000000000000003964 101.0
HKD2_k127_1352680_8 outer membrane efflux protein - - - 0.0000002918 57.0
HKD2_k127_1376540_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 543.0
HKD2_k127_1376540_1 alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 461.0
HKD2_k127_1376540_10 Transcriptional regulator K13653 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019243,GO:0019249,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046185,GO:0046394,GO:0051596,GO:0061727,GO:0071704,GO:0072330,GO:1901575,GO:1901576,GO:1901615,GO:1901617 - 0.0000000000000000000000000000000000000000000003247 175.0
HKD2_k127_1376540_11 Transcriptional regulator K13653 - - 0.00000000000000000000000000000000000000000006245 168.0
HKD2_k127_1376540_12 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000002896 156.0
HKD2_k127_1376540_13 positive regulation of growth rate - - - 0.00000000000000000000000000000000000005313 158.0
HKD2_k127_1376540_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000004393 148.0
HKD2_k127_1376540_15 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000508 128.0
HKD2_k127_1376540_16 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000003484 117.0
HKD2_k127_1376540_17 PASTA domain K12132 - 2.7.11.1 0.000000000000000002131 94.0
HKD2_k127_1376540_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000001546 91.0
HKD2_k127_1376540_19 - - - - 0.0000000000004822 74.0
HKD2_k127_1376540_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 399.0
HKD2_k127_1376540_20 Polymer-forming cytoskeletal - - - 0.000000008607 63.0
HKD2_k127_1376540_21 AntiSigma factor - - - 0.00004163 55.0
HKD2_k127_1376540_22 Gram-negative bacterial TonB protein C-terminal - - - 0.0004973 50.0
HKD2_k127_1376540_3 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 351.0
HKD2_k127_1376540_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 310.0
HKD2_k127_1376540_5 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002475 283.0
HKD2_k127_1376540_6 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005987 246.0
HKD2_k127_1376540_7 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000002789 241.0
HKD2_k127_1376540_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000001782 231.0
HKD2_k127_1376540_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000001426 182.0
HKD2_k127_138697_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 466.0
HKD2_k127_138697_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 419.0
HKD2_k127_138697_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K19517 - 2.7.1.15,2.7.1.64 0.00000000000000000000000000000000000000003759 172.0
HKD2_k127_138697_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000008808 141.0
HKD2_k127_1400585_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 398.0
HKD2_k127_1400585_1 cytochrome c biogenesis protein - - - 0.0000000000000000000008912 109.0
HKD2_k127_1400585_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000006884 69.0
HKD2_k127_1403478_0 beta-galactosidase activity - - - 0.0 1077.0
HKD2_k127_1403478_1 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 514.0
HKD2_k127_1403478_2 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001098 261.0
HKD2_k127_1403478_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000005825 157.0
HKD2_k127_1403478_4 4Fe-4S binding domain - - - 0.000000000000555 79.0
HKD2_k127_1403478_6 response regulator K02481,K07713 - - 0.000000004384 70.0
HKD2_k127_1403478_7 - K07039 - - 0.000004552 54.0
HKD2_k127_141523_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 558.0
HKD2_k127_141523_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 527.0
HKD2_k127_141523_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000006656 168.0
HKD2_k127_141523_11 Radical SAM - - - 0.0000000000000000000000000000000000000005299 166.0
HKD2_k127_141523_12 - - - - 0.000000000000000000000008137 118.0
HKD2_k127_141523_13 PFAM Radical SAM - - - 0.00000000000009916 79.0
HKD2_k127_141523_14 - - - - 0.0000000003618 72.0
HKD2_k127_141523_2 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 374.0
HKD2_k127_141523_3 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 350.0
HKD2_k127_141523_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 336.0
HKD2_k127_141523_5 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 347.0
HKD2_k127_141523_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002746 282.0
HKD2_k127_141523_7 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002015 276.0
HKD2_k127_141523_8 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000003836 249.0
HKD2_k127_141523_9 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003536 232.0
HKD2_k127_1421889_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 535.0
HKD2_k127_1421889_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 506.0
HKD2_k127_1421889_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000004132 112.0
HKD2_k127_1421889_11 tigr00255 - - - 0.0006177 53.0
HKD2_k127_1421889_2 NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 458.0
HKD2_k127_1421889_3 Bacterial sugar transferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 413.0
HKD2_k127_1421889_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 365.0
HKD2_k127_1421889_5 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002508 276.0
HKD2_k127_1421889_6 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009735 264.0
HKD2_k127_1421889_7 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000001112 202.0
HKD2_k127_1421889_8 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000001553 183.0
HKD2_k127_1421889_9 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000001416 158.0
HKD2_k127_143239_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.347e-281 906.0
HKD2_k127_143239_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.108e-235 751.0
HKD2_k127_143239_10 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002852 256.0
HKD2_k127_143239_11 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001795 243.0
HKD2_k127_143239_12 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000001349 233.0
HKD2_k127_143239_13 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000002629 177.0
HKD2_k127_143239_14 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000001593 155.0
HKD2_k127_143239_15 - - - - 0.0000000000000000000000000000000002339 139.0
HKD2_k127_143239_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000002374 114.0
HKD2_k127_143239_17 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.000000000000000000005385 106.0
HKD2_k127_143239_18 Polymer-forming cytoskeletal - - - 0.0000000000000000000552 100.0
HKD2_k127_143239_19 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000003791 99.0
HKD2_k127_143239_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.067e-228 717.0
HKD2_k127_143239_20 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000005941 101.0
HKD2_k127_143239_21 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000001978 90.0
HKD2_k127_143239_22 shape-determining protein MreD K03571 - - 0.00006955 55.0
HKD2_k127_143239_23 cell adhesion - - - 0.0007024 53.0
HKD2_k127_143239_3 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 475.0
HKD2_k127_143239_4 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 452.0
HKD2_k127_143239_5 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 443.0
HKD2_k127_143239_6 NUBPL iron-transfer P-loop NTPase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 337.0
HKD2_k127_143239_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 304.0
HKD2_k127_143239_8 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 298.0
HKD2_k127_143239_9 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003519 287.0
HKD2_k127_1456008_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 437.0
HKD2_k127_1456008_1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 374.0
HKD2_k127_1456008_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000342 177.0
HKD2_k127_1456274_0 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 442.0
HKD2_k127_1456274_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001701 280.0
HKD2_k127_1456274_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006115 258.0
HKD2_k127_1456274_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000008081 258.0
HKD2_k127_1456274_4 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000002236 244.0
HKD2_k127_1456274_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000009663 219.0
HKD2_k127_1456274_6 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000003094 186.0
HKD2_k127_1456274_7 membrane - - - 0.0000000000000000000000000000000000004698 151.0
HKD2_k127_1456274_8 Chorismate mutase type II K04093 - 5.4.99.5 0.000000000000000000001947 108.0
HKD2_k127_150616_0 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006372 256.0
HKD2_k127_150616_1 PFAM regulatory protein ArsR - - - 0.00000000000000000000000000000000000000000004078 163.0
HKD2_k127_150616_2 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.0000000000000000000000000000000000001519 156.0
HKD2_k127_150616_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000001811 151.0
HKD2_k127_150616_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000003361 145.0
HKD2_k127_150616_5 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000005912 128.0
HKD2_k127_150616_6 - - - - 0.0000000000000004997 85.0
HKD2_k127_150616_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000684 57.0
HKD2_k127_1521496_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 1.982e-296 919.0
HKD2_k127_1521496_1 belongs to the aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 587.0
HKD2_k127_1521496_10 ethanolamine catabolic process K04027 - - 0.000000000000000000000000000003468 128.0
HKD2_k127_1521496_11 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000002065 120.0
HKD2_k127_1521496_12 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.0000000000000000000000000005783 126.0
HKD2_k127_1521496_13 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000000007935 104.0
HKD2_k127_1521496_14 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000002534 63.0
HKD2_k127_1521496_15 testosterone 17-beta-dehydrogenase (NADP+) activity K00826 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006694,GO:0006703,GO:0006706,GO:0008150,GO:0008152,GO:0008202,GO:0008210,GO:0008610,GO:0009056,GO:0009058,GO:0009987,GO:0010817,GO:0016042,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0033764,GO:0034754,GO:0042445,GO:0042446,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0047045,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.6.1.42 0.000009793 48.0
HKD2_k127_1521496_16 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0001206 52.0
HKD2_k127_1521496_2 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 482.0
HKD2_k127_1521496_3 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 429.0
HKD2_k127_1521496_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 384.0
HKD2_k127_1521496_5 RnfC Barrel sandwich hybrid domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 370.0
HKD2_k127_1521496_6 propanediol catabolic process K15024 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 300.0
HKD2_k127_1521496_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000002545 194.0
HKD2_k127_1521496_8 BMC - - - 0.0000000000000000000000000000000000000000001355 165.0
HKD2_k127_1521496_9 COG1349 Transcriptional regulators of sugar metabolism - - - 0.000000000000000000000000000000000000000000555 180.0
HKD2_k127_1541425_0 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.00000000000000000000000000000000000000000000004741 180.0
HKD2_k127_1541425_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000003617 136.0
HKD2_k127_1541425_2 competence protein - - - 0.00000000000000000000000000001691 134.0
HKD2_k127_1552740_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 582.0
HKD2_k127_1552740_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 302.0
HKD2_k127_1552740_2 endo-1,4-beta-xylanase activity K01181 - 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
HKD2_k127_1552740_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000007309 250.0
HKD2_k127_1552740_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000004936 228.0
HKD2_k127_1552740_5 - - - - 0.000000000000000000000000000000000000000000000000001684 207.0
HKD2_k127_1552740_6 Protein of unknown function (DUF3179) - - - 0.000000000000000000000000000000001696 150.0
HKD2_k127_1552740_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000002799 134.0
HKD2_k127_1552740_8 - - - - 0.00000000000000004386 98.0
HKD2_k127_1552740_9 tetratricopeptide repeat - - - 0.00002802 56.0
HKD2_k127_1556139_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 542.0
HKD2_k127_1565855_0 COG0433 Predicted ATPase K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 604.0
HKD2_k127_1565855_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006927 270.0
HKD2_k127_1565855_2 Belongs to the N-Me-Phe pilin family - - - 0.000000000000000000000000000000000000000112 163.0
HKD2_k127_1565855_3 ATPase involved in DNA repair K03546 - - 0.0000000000000000000000000000000000000001139 170.0
HKD2_k127_1565855_4 DNA-binding transcription factor activity - - - 0.0000000000002957 74.0
HKD2_k127_1565855_5 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000003315 70.0
HKD2_k127_1569085_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.095e-312 983.0
HKD2_k127_1569085_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.903e-242 777.0
HKD2_k127_1569085_10 Metallo-beta-lactamase superfamily K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001987 293.0
HKD2_k127_1569085_11 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000147 259.0
HKD2_k127_1569085_12 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001771 262.0
HKD2_k127_1569085_13 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000001313 224.0
HKD2_k127_1569085_14 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000002396 228.0
HKD2_k127_1569085_15 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000148 216.0
HKD2_k127_1569085_16 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000000000000000000000000001306 191.0
HKD2_k127_1569085_17 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000002916 193.0
HKD2_k127_1569085_18 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000006048 154.0
HKD2_k127_1569085_19 STAS domain K04749 - - 0.0000000000000000000000001343 110.0
HKD2_k127_1569085_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 536.0
HKD2_k127_1569085_20 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000007433 106.0
HKD2_k127_1569085_21 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000359 115.0
HKD2_k127_1569085_22 - - - - 0.00000000000000000001572 102.0
HKD2_k127_1569085_23 outer membrane autotransporter barrel domain protein - - - 0.00000000000000000536 91.0
HKD2_k127_1569085_24 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000004951 84.0
HKD2_k127_1569085_25 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000002054 83.0
HKD2_k127_1569085_26 PBS lyase HEAT-like repeat - - - 0.000000001962 70.0
HKD2_k127_1569085_28 S-layer homology domain - - - 0.0000001275 65.0
HKD2_k127_1569085_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 462.0
HKD2_k127_1569085_30 Domain of unknown function (DUF1844) - - - 0.0000002338 61.0
HKD2_k127_1569085_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 467.0
HKD2_k127_1569085_5 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 393.0
HKD2_k127_1569085_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 379.0
HKD2_k127_1569085_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 370.0
HKD2_k127_1569085_8 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 319.0
HKD2_k127_1569085_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002318 309.0
HKD2_k127_1570815_0 Carbon starvation protein CstA K06200 - - 2.235e-273 861.0
HKD2_k127_1570815_1 PFAM Pyrrolo-quinoline quinone K00117 - 1.1.5.2 5.7e-259 833.0
HKD2_k127_1570815_10 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007403 289.0
HKD2_k127_1570815_11 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002138 276.0
HKD2_k127_1570815_12 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001631 276.0
HKD2_k127_1570815_13 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000000000000000006109 153.0
HKD2_k127_1570815_14 FeS assembly SUF system protein SufT - - - 0.0000000000000000001281 89.0
HKD2_k127_1570815_15 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000004958 88.0
HKD2_k127_1570815_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.871e-195 614.0
HKD2_k127_1570815_3 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 451.0
HKD2_k127_1570815_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 391.0
HKD2_k127_1570815_5 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 384.0
HKD2_k127_1570815_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 390.0
HKD2_k127_1570815_7 InterPro IPR010496 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 377.0
HKD2_k127_1570815_8 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 352.0
HKD2_k127_1570815_9 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 293.0
HKD2_k127_1584555_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 1.197e-203 643.0
HKD2_k127_1584555_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 2.416e-196 637.0
HKD2_k127_1584555_10 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 351.0
HKD2_k127_1584555_11 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000006732 274.0
HKD2_k127_1584555_12 Cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000001453 241.0
HKD2_k127_1584555_13 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000005298 248.0
HKD2_k127_1584555_14 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001813 241.0
HKD2_k127_1584555_15 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000003255 213.0
HKD2_k127_1584555_16 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000064 217.0
HKD2_k127_1584555_17 2Fe-2S -binding K13483 - - 0.00000000000000000000000000000000000000000000004517 197.0
HKD2_k127_1584555_18 Major facilitator superfamily K08161 - - 0.000000000000000000000000000000000000000005887 173.0
HKD2_k127_1584555_19 Thioredoxin-like - - - 0.00000000000000000000000001038 115.0
HKD2_k127_1584555_2 L-asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 607.0
HKD2_k127_1584555_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000975 106.0
HKD2_k127_1584555_21 - - - - 0.0000000000000000008226 89.0
HKD2_k127_1584555_22 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.000000000006278 80.0
HKD2_k127_1584555_23 Ceramide hydroxylase involved in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids. Hydroxylates the very long chain fatty acid of ceramides at C2 and C3 K19703 GO:0000170,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006643,GO:0006644,GO:0006664,GO:0006665,GO:0006673,GO:0006675,GO:0006687,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016021,GO:0016491,GO:0019637,GO:0019752,GO:0030148,GO:0031224,GO:0031984,GO:0032787,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046467,GO:0055114,GO:0071704,GO:0080132,GO:0098827,GO:1901135,GO:1901564,GO:1901566,GO:1901576,GO:1903509 1.14.18.6 0.00000000001144 75.0
HKD2_k127_1584555_24 Protein of unknown function (DUF1343) - - - 0.000004673 49.0
HKD2_k127_1584555_26 tetratricopeptide repeat - - - 0.0002496 52.0
HKD2_k127_1584555_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 451.0
HKD2_k127_1584555_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 446.0
HKD2_k127_1584555_5 GatB/GatE catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 459.0
HKD2_k127_1584555_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 384.0
HKD2_k127_1584555_7 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 393.0
HKD2_k127_1584555_8 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 370.0
HKD2_k127_1584555_9 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 352.0
HKD2_k127_1615097_0 peptidase K01415,K07386 - 3.4.24.71 9.59e-232 760.0
HKD2_k127_1615097_1 Cyclomaltodextrinase, N-terminal K21575 - 3.2.1.135 3.909e-223 735.0
HKD2_k127_1615097_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003915 282.0
HKD2_k127_1615097_11 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002064 246.0
HKD2_k127_1615097_12 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000009792 200.0
HKD2_k127_1615097_13 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000002003 183.0
HKD2_k127_1615097_14 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000002084 171.0
HKD2_k127_1615097_15 TIGRFAM folate-binding protein YgfZ K06980 - - 0.0000000000000000000000000000000000000002156 163.0
HKD2_k127_1615097_16 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000001477 136.0
HKD2_k127_1615097_17 Transcriptional regulator - - - 0.00000000000000000000000000000003761 138.0
HKD2_k127_1615097_18 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000004852 118.0
HKD2_k127_1615097_19 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000004544 54.0
HKD2_k127_1615097_2 Cytochrome c554 and c-prime - - - 1.321e-211 676.0
HKD2_k127_1615097_20 Late embryogenesis abundant protein - - - 0.0001486 52.0
HKD2_k127_1615097_3 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 630.0
HKD2_k127_1615097_4 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 543.0
HKD2_k127_1615097_5 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 528.0
HKD2_k127_1615097_6 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 377.0
HKD2_k127_1615097_7 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 327.0
HKD2_k127_1615097_8 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 315.0
HKD2_k127_1615097_9 isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002612 264.0
HKD2_k127_1622465_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 377.0
HKD2_k127_1622465_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 334.0
HKD2_k127_1622465_10 COG1404 Subtilisin-like serine proteases K13276 - - 0.00008585 53.0
HKD2_k127_1622465_2 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001026 287.0
HKD2_k127_1622465_3 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000009159 254.0
HKD2_k127_1622465_4 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000001734 244.0
HKD2_k127_1622465_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000163 170.0
HKD2_k127_1622465_6 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000006748 140.0
HKD2_k127_1622465_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000001568 75.0
HKD2_k127_1622465_8 Putative cell wall binding repeat 2 K03641 - - 0.0000000009306 69.0
HKD2_k127_1622465_9 - K05826 - - 0.00000005359 57.0
HKD2_k127_1664506_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.4e-322 1019.0
HKD2_k127_1664506_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.054e-220 701.0
HKD2_k127_1664506_10 DksA TraR C4-type K06204 - - 0.00000000008988 68.0
HKD2_k127_1664506_11 zinc-ribbon domain - - - 0.000000437 59.0
HKD2_k127_1664506_12 Protein of unknown function (DUF429) - - - 0.0000006876 61.0
HKD2_k127_1664506_13 PilZ domain - - - 0.0006742 53.0
HKD2_k127_1664506_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 6.524e-220 705.0
HKD2_k127_1664506_3 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 412.0
HKD2_k127_1664506_4 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000001649 241.0
HKD2_k127_1664506_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000002612 237.0
HKD2_k127_1664506_6 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000004931 194.0
HKD2_k127_1664506_7 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000001166 166.0
HKD2_k127_1664506_8 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000001651 160.0
HKD2_k127_1664506_9 SdrD B-like domain - - - 0.00000000000000000000000000001842 138.0
HKD2_k127_1741460_0 ACT domain K12524 - 1.1.1.3,2.7.2.4 3.333e-236 756.0
HKD2_k127_1741460_1 Homoserine O-succinyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 499.0
HKD2_k127_1741460_2 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 404.0
HKD2_k127_1741460_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008097 302.0
HKD2_k127_1741460_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000002021 256.0
HKD2_k127_1741460_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000005319 226.0
HKD2_k127_1741460_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000001696 87.0
HKD2_k127_174159_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 542.0
HKD2_k127_174159_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 373.0
HKD2_k127_174159_2 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 357.0
HKD2_k127_174159_3 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008259 254.0
HKD2_k127_174159_4 PFAM fumarate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000002192 233.0
HKD2_k127_174159_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000001748 160.0
HKD2_k127_1759394_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 466.0
HKD2_k127_1759394_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000002273 258.0
HKD2_k127_1759394_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000001285 226.0
HKD2_k127_1759394_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000002803 190.0
HKD2_k127_1759394_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000014 161.0
HKD2_k127_1759394_5 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000002227 136.0
HKD2_k127_1760629_0 amino acid transport K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 504.0
HKD2_k127_1760629_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 356.0
HKD2_k127_1760629_10 COG2146 Ferredoxin subunits of nitrite reductase and K00363 - 1.7.1.15 0.000000000000000000000003579 105.0
HKD2_k127_1760629_11 Tfp pilus assembly protein FimV - - - 0.000000000000000001161 93.0
HKD2_k127_1760629_12 Preprotein translocase SecG subunit K03075 - - 0.000000000000000007118 89.0
HKD2_k127_1760629_13 - - - - 0.00000006586 66.0
HKD2_k127_1760629_14 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000002161 64.0
HKD2_k127_1760629_15 PilZ domain - - - 0.0007048 51.0
HKD2_k127_1760629_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 342.0
HKD2_k127_1760629_3 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 335.0
HKD2_k127_1760629_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004488 291.0
HKD2_k127_1760629_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000001408 188.0
HKD2_k127_1760629_6 - - - - 0.00000000000000000000000000000000000000001658 164.0
HKD2_k127_1760629_7 - - - - 0.00000000000000000000000000000000000001046 166.0
HKD2_k127_1760629_8 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000001467 164.0
HKD2_k127_1760629_9 - - - - 0.0000000000000000000000000000000000003488 164.0
HKD2_k127_1762185_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 527.0
HKD2_k127_1762185_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 439.0
HKD2_k127_1762185_10 Psort location Cytoplasmic, score K09707 - - 0.0000000000000000000000000000000000000009081 152.0
HKD2_k127_1762185_11 DoxX - - - 0.0000000000000000000000000000001956 131.0
HKD2_k127_1762185_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 336.0
HKD2_k127_1762185_3 Belongs to the pseudouridine synthase RsuA family K06178,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000513 234.0
HKD2_k127_1762185_4 AAA domain (Cdc48 subfamily) K03544 - - 0.0000000000000000000000000000000000000000000000000000000000034 222.0
HKD2_k127_1762185_5 Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000004289 209.0
HKD2_k127_1762185_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000001462 207.0
HKD2_k127_1762185_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000007411 190.0
HKD2_k127_1762185_8 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000002393 175.0
HKD2_k127_1762185_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000005318 171.0
HKD2_k127_177418_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 437.0
HKD2_k127_177418_1 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 402.0
HKD2_k127_177418_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 381.0
HKD2_k127_177418_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 337.0
HKD2_k127_177418_4 Adenosine/AMP deaminase K01488,K19572 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000002246 263.0
HKD2_k127_177418_5 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000000006152 228.0
HKD2_k127_177418_7 PBS lyase HEAT-like repeat - - - 0.00000000004899 75.0
HKD2_k127_177418_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000004143 67.0
HKD2_k127_1868801_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 488.0
HKD2_k127_1868801_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 314.0
HKD2_k127_1868801_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004364 267.0
HKD2_k127_1868801_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000002084 164.0
HKD2_k127_1868801_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000002748 151.0
HKD2_k127_1868801_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000004346 102.0
HKD2_k127_1868801_6 Jag_N K06346 - - 0.00000000000002034 87.0
HKD2_k127_1868801_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000148 79.0
HKD2_k127_1868801_8 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001381 69.0
HKD2_k127_1868801_9 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.0000000001928 68.0
HKD2_k127_1870099_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 483.0
HKD2_k127_1870099_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 409.0
HKD2_k127_1870099_10 Predicted membrane protein (DUF2232) - - - 0.00004657 55.0
HKD2_k127_1870099_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000009947 189.0
HKD2_k127_1870099_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000002936 162.0
HKD2_k127_1870099_4 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000005507 153.0
HKD2_k127_1870099_5 Could be involved in septation K06412 - - 0.000000000000000000000000001275 119.0
HKD2_k127_1870099_6 Ribosomal protein S18 K02963 - - 0.000000000000000000000000002263 114.0
HKD2_k127_1870099_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000006484 107.0
HKD2_k127_1870099_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000002932 107.0
HKD2_k127_1870099_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000002331 74.0
HKD2_k127_1890815_0 Belongs to the DegT DnrJ EryC1 family K02805,K13010,K18653 - 2.6.1.102,2.6.1.104,2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 336.0
HKD2_k127_1890815_1 PFAM Glycosyl transferase family 2 K07027 - - 0.00000000000000000000000000004166 134.0
HKD2_k127_1890815_2 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000005095 103.0
HKD2_k127_1890815_3 Psort location CytoplasmicMembrane, score - - - 0.00000000000000001074 98.0
HKD2_k127_1890815_4 Bacterial membrane protein, YfhO - - - 0.00000000000000003131 96.0
HKD2_k127_1915133_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 326.0
HKD2_k127_1915133_1 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000000002229 215.0
HKD2_k127_1915133_2 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000002893 197.0
HKD2_k127_1915133_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000006599 177.0
HKD2_k127_1915133_4 Zn peptidase - - - 0.000000000000000000000000000000000000000000007825 169.0
HKD2_k127_1915133_5 converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.000000000000000000000000000000000000000005986 173.0
HKD2_k127_1915133_6 COG0457 FOG TPR repeat - - - 0.00000001162 67.0
HKD2_k127_1915133_7 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000114 61.0
HKD2_k127_2029176_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000112 108.0
HKD2_k127_2029176_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000004597 68.0
HKD2_k127_2137373_0 TonB-dependent receptor - - - 0.0 1284.0
HKD2_k127_2137373_1 Sodium:alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 587.0
HKD2_k127_2137373_10 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000165 260.0
HKD2_k127_2137373_11 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000000000000000000000000000000000000000000000006469 245.0
HKD2_k127_2137373_12 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000431 209.0
HKD2_k127_2137373_13 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000000000001724 219.0
HKD2_k127_2137373_14 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000001011 203.0
HKD2_k127_2137373_15 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000197 186.0
HKD2_k127_2137373_16 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000000000000008008 158.0
HKD2_k127_2137373_17 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000003849 112.0
HKD2_k127_2137373_2 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 477.0
HKD2_k127_2137373_3 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 460.0
HKD2_k127_2137373_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 422.0
HKD2_k127_2137373_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 402.0
HKD2_k127_2137373_6 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009901 336.0
HKD2_k127_2137373_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 305.0
HKD2_k127_2137373_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001882 298.0
HKD2_k127_2137373_9 PFAM Glycosyl transferase, family K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
HKD2_k127_2148244_0 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 395.0
HKD2_k127_2148244_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000003879 218.0
HKD2_k127_2148244_2 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000003915 93.0
HKD2_k127_2148244_3 Histidine kinase-like ATPase domain - - - 0.0000000000000000003074 94.0
HKD2_k127_2148244_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000003254 69.0
HKD2_k127_2150113_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1314.0
HKD2_k127_2150113_1 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.841e-202 666.0
HKD2_k127_2150113_2 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001178 286.0
HKD2_k127_2150113_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000008036 258.0
HKD2_k127_2150113_4 phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000008439 210.0
HKD2_k127_2150113_5 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000005031 214.0
HKD2_k127_2150113_6 - - - - 0.00000001095 61.0
HKD2_k127_2150113_7 Protein of unknown function (DUF533) - - - 0.0000005503 63.0
HKD2_k127_220572_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HKD2_k127_220572_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.00000000000000000000000000000000000000000000000000000000000145 228.0
HKD2_k127_220572_2 Iodothyronine deiodinase - - - 0.00000000000000000000000000000000000000002618 158.0
HKD2_k127_220572_3 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000486 162.0
HKD2_k127_2263651_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 1.365e-238 773.0
HKD2_k127_2263651_1 Sulfatase K01137 - 3.1.6.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 392.0
HKD2_k127_2263651_2 LOR/SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 388.0
HKD2_k127_2263651_3 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 302.0
HKD2_k127_2263651_4 Predicted membrane protein (DUF2127) - - - 0.0000000000000000008849 89.0
HKD2_k127_2263651_5 lipolytic protein G-D-S-L family K01183 - 3.2.1.14 0.000000000000000004499 96.0
HKD2_k127_234679_0 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 597.0
HKD2_k127_234679_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 571.0
HKD2_k127_234679_10 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000003704 140.0
HKD2_k127_234679_11 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000007491 86.0
HKD2_k127_234679_12 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000004488 68.0
HKD2_k127_234679_13 Patatin-like phospholipase - - - 0.0005305 52.0
HKD2_k127_234679_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 353.0
HKD2_k127_234679_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 362.0
HKD2_k127_234679_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 319.0
HKD2_k127_234679_5 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004481 246.0
HKD2_k127_234679_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001969 238.0
HKD2_k127_234679_7 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000732 189.0
HKD2_k127_234679_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000005256 166.0
HKD2_k127_2383374_0 Belongs to the aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 328.0
HKD2_k127_2383374_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000003183 158.0
HKD2_k127_2383374_2 belongs to the aldehyde dehydrogenase family. ALDH1L subfamily K00289 GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009109,GO:0009256,GO:0009258,GO:0009396,GO:0009397,GO:0009987,GO:0016053,GO:0016054,GO:0016155,GO:0016491,GO:0016620,GO:0016645,GO:0016646,GO:0016903,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019752,GO:0031974,GO:0032991,GO:0033721,GO:0034641,GO:0042219,GO:0042398,GO:0042558,GO:0042559,GO:0042560,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046394,GO:0046395,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046700,GO:0051186,GO:0051187,GO:0051188,GO:0055114,GO:0070013,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.5.1.6 0.0003852 45.0
HKD2_k127_23875_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 1.413e-249 789.0
HKD2_k127_23875_1 Alpha-L-fucosidase K01206,K07114,K07126 - 3.2.1.51 1.87e-212 689.0
HKD2_k127_23875_10 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 484.0
HKD2_k127_23875_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 447.0
HKD2_k127_23875_12 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 426.0
HKD2_k127_23875_13 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 411.0
HKD2_k127_23875_14 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 361.0
HKD2_k127_23875_15 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 353.0
HKD2_k127_23875_16 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 350.0
HKD2_k127_23875_17 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 330.0
HKD2_k127_23875_18 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 303.0
HKD2_k127_23875_19 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 274.0
HKD2_k127_23875_2 Prolyl oligopeptidase family - - - 3.655e-212 678.0
HKD2_k127_23875_20 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003869 275.0
HKD2_k127_23875_21 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000001206 236.0
HKD2_k127_23875_22 RbsD / FucU transport protein family K02431 - 5.1.3.29 0.000000000000000000000000000000000000000000000000000000000000547 214.0
HKD2_k127_23875_23 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000001422 214.0
HKD2_k127_23875_24 Ndr family - - - 0.0000000000000000000000000000000000000000000000000000002145 209.0
HKD2_k127_23875_25 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000001177 200.0
HKD2_k127_23875_26 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.00000000000000000000000000000000000000000000000008423 199.0
HKD2_k127_23875_27 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000003005 190.0
HKD2_k127_23875_28 COG1121 ABC-type Mn Zn transport systems ATPase component K09817 - - 0.000000000000000000000000000000000000000000002071 186.0
HKD2_k127_23875_29 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.00000000000000000000000000000000000000000218 178.0
HKD2_k127_23875_3 Peptidase family M28 - - - 1.287e-199 638.0
HKD2_k127_23875_30 Belongs to the bacterial solute-binding protein 9 family K09818 - - 0.0000000000000000000000000000000000000256 157.0
HKD2_k127_23875_31 transmembrane transport - - - 0.0000000000000000000000000002898 125.0
HKD2_k127_23875_32 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000007529 113.0
HKD2_k127_23875_33 - - - - 0.000000000000000000000008623 117.0
HKD2_k127_23875_34 - - - - 0.0000000000000000002621 89.0
HKD2_k127_23875_35 ThiS family K03636 - - 0.00000000000004072 78.0
HKD2_k127_23875_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 647.0
HKD2_k127_23875_5 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 572.0
HKD2_k127_23875_6 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 541.0
HKD2_k127_23875_7 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 533.0
HKD2_k127_23875_8 Aldo/keto reductase family K00002 - 1.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 512.0
HKD2_k127_23875_9 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 503.0
HKD2_k127_2396967_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004991 282.0
HKD2_k127_2396967_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000961 237.0
HKD2_k127_2396967_2 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000003591 238.0
HKD2_k127_2396967_3 PAS domain - - - 0.0000000000000000000000000000000000000001053 173.0
HKD2_k127_2396967_4 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000004013 114.0
HKD2_k127_2472668_0 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 566.0
HKD2_k127_2472668_1 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 471.0
HKD2_k127_2472668_2 - - - - 0.00000000000000000000000000000000000000000000000000000000006105 229.0
HKD2_k127_2472668_3 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000001255 228.0
HKD2_k127_2472668_4 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000001003 181.0
HKD2_k127_2472668_5 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000001316 158.0
HKD2_k127_2472668_6 nucleotide metabolic process - - - 0.000000000000000000000000000000000000001552 168.0
HKD2_k127_2496228_0 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 533.0
HKD2_k127_2496228_1 PAS domain containing protein K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004703 286.0
HKD2_k127_2496228_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000006259 224.0
HKD2_k127_2496228_3 Domain of unknown function (DUF4184) - - - 0.0000000000000000000000000000009475 132.0
HKD2_k127_2496228_4 response regulator - - - 0.00000000000001501 79.0
HKD2_k127_2496228_5 His Kinase A (phosphoacceptor) domain - - - 0.0000008534 63.0
HKD2_k127_2560131_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.222e-289 906.0
HKD2_k127_2560131_1 family 2, sugar binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 622.0
HKD2_k127_2560131_10 DUF218 domain - - - 0.00000000000000000442 94.0
HKD2_k127_2560131_11 BON domain - - - 0.00000000000000004043 92.0
HKD2_k127_2560131_12 Protein of unknown function (DUF2911) - - - 0.0000000000000001059 87.0
HKD2_k127_2560131_13 YceI-like domain - - - 0.0000000000000009006 90.0
HKD2_k127_2560131_14 Rieske [2Fe-2S] domain - - - 0.000000000000001751 84.0
HKD2_k127_2560131_15 - - - - 0.0000000000000116 87.0
HKD2_k127_2560131_16 - - - - 0.0000000000003322 78.0
HKD2_k127_2560131_18 Sulfurtransferase - - - 0.000000000001419 70.0
HKD2_k127_2560131_19 Carboxymuconolactone decarboxylase family - - - 0.000000005269 64.0
HKD2_k127_2560131_2 C-terminus of AA_permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 510.0
HKD2_k127_2560131_20 SNARE associated Golgi protein - - - 0.00000001613 60.0
HKD2_k127_2560131_3 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 401.0
HKD2_k127_2560131_4 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 402.0
HKD2_k127_2560131_5 Catalyzes the sodium-dependent transport of glutamate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 379.0
HKD2_k127_2560131_6 Ferritin-like domain K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000003109 199.0
HKD2_k127_2560131_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000005147 171.0
HKD2_k127_2560131_8 Flavin reductase like domain - - - 0.0000000000000000000000000000000000001914 158.0
HKD2_k127_2560131_9 alpha beta K06889 - - 0.0000000000000000000000004613 116.0
HKD2_k127_2575606_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 569.0
HKD2_k127_2575606_1 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 373.0
HKD2_k127_2575606_2 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 289.0
HKD2_k127_2575606_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000001151 190.0
HKD2_k127_2575606_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000003966 158.0
HKD2_k127_2575606_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000004757 95.0
HKD2_k127_2575606_6 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000007613 91.0
HKD2_k127_2575606_7 Protein of unknown function (DUF2752) - - - 0.000001051 60.0
HKD2_k127_2575606_8 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000002216 54.0
HKD2_k127_2575606_9 histidine kinase HAMP region domain protein K03406 - - 0.0002022 53.0
HKD2_k127_2597052_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.078e-204 653.0
HKD2_k127_2597052_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.953e-198 662.0
HKD2_k127_2597052_10 PFAM CHAD domain containing protein - - - 0.000000001763 68.0
HKD2_k127_2597052_11 Thioredoxin-like - - - 0.000000002655 60.0
HKD2_k127_2597052_12 Protein of unknown function DUF47 K07220 - - 0.000001104 50.0
HKD2_k127_2597052_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 407.0
HKD2_k127_2597052_3 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 369.0
HKD2_k127_2597052_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 339.0
HKD2_k127_2597052_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000006007 209.0
HKD2_k127_2597052_6 PFAM response regulator receiver K07657 - - 0.00000000000000000000000000000000000000000000000000002643 192.0
HKD2_k127_2597052_7 Thioredoxin-like - - - 0.0000000000000000000000000000000000000004778 174.0
HKD2_k127_2597052_8 Phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000456 100.0
HKD2_k127_2597052_9 carboxymuconolactone decarboxylase - - - 0.0000000000001536 76.0
HKD2_k127_2602160_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.291e-249 784.0
HKD2_k127_2602160_1 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 1.207e-203 642.0
HKD2_k127_2602160_10 - - - - 0.0000000000000000000001524 108.0
HKD2_k127_2602160_2 Sulfate permease family K03321 - - 3.437e-198 641.0
HKD2_k127_2602160_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 475.0
HKD2_k127_2602160_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 462.0
HKD2_k127_2602160_5 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 383.0
HKD2_k127_2602160_6 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 327.0
HKD2_k127_2602160_7 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006929 275.0
HKD2_k127_2602160_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000001033 209.0
HKD2_k127_2602160_9 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000000000009902 177.0
HKD2_k127_2606604_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 338.0
HKD2_k127_2606604_1 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000445 212.0
HKD2_k127_2606604_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000001629 143.0
HKD2_k127_2611974_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 7.062e-230 726.0
HKD2_k127_2611974_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 525.0
HKD2_k127_2611974_10 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000004666 62.0
HKD2_k127_2611974_11 Thiol disulfide interchange protein dsbA - - - 0.0006609 49.0
HKD2_k127_2611974_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 473.0
HKD2_k127_2611974_3 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007811 334.0
HKD2_k127_2611974_4 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005912 299.0
HKD2_k127_2611974_5 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002948 300.0
HKD2_k127_2611974_6 - - - - 0.000000000000000000000000000003922 139.0
HKD2_k127_2611974_7 Methyltransferase domain - - - 0.000000000000000000000000002946 126.0
HKD2_k127_2611974_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000001145 124.0
HKD2_k127_2611974_9 NUDIX domain - - - 0.000000000000000000004052 106.0
HKD2_k127_2650277_0 Belongs to the glycosyl hydrolase 67 family K01235 - 3.2.1.139 0.0 1027.0
HKD2_k127_2650277_1 response regulator - - - 4.557e-246 797.0
HKD2_k127_2650277_2 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 2.436e-219 692.0
HKD2_k127_2650277_3 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 504.0
HKD2_k127_2650277_4 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 376.0
HKD2_k127_2650277_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 298.0
HKD2_k127_2650277_6 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001434 269.0
HKD2_k127_2650277_7 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007648 247.0
HKD2_k127_2650277_8 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000004789 173.0
HKD2_k127_2650277_9 WD40 domain protein beta Propeller - - - 0.000000000000000000005865 108.0
HKD2_k127_2657639_0 carboxylic acid catabolic process K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 532.0
HKD2_k127_2657639_1 glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 464.0
HKD2_k127_2657639_10 - - - - 0.0000000000000000000000000000000000007418 149.0
HKD2_k127_2657639_11 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000001461 151.0
HKD2_k127_2657639_12 Putative adhesin - - - 0.00000000000000000000000000114 130.0
HKD2_k127_2657639_13 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000001862 122.0
HKD2_k127_2657639_14 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000002585 86.0
HKD2_k127_2657639_15 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000001774 82.0
HKD2_k127_2657639_16 Rhodanese-like domain - - - 0.000000000008421 77.0
HKD2_k127_2657639_17 Domain of unknown function (DUF4349) - - - 0.00003471 55.0
HKD2_k127_2657639_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 415.0
HKD2_k127_2657639_3 Pyridoxal-dependent decarboxylase conserved domain K00486,K01593 - 1.14.13.9,4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 398.0
HKD2_k127_2657639_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002061 248.0
HKD2_k127_2657639_5 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000000000000001633 239.0
HKD2_k127_2657639_6 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000001304 217.0
HKD2_k127_2657639_7 actin binding - - - 0.000000000000000000000000000000000000000000001837 172.0
HKD2_k127_2657639_8 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000813 161.0
HKD2_k127_2657639_9 Mannosyltransferase (PIG-V) - - - 0.0000000000000000000000000000000000000664 163.0
HKD2_k127_2658798_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 3.959e-197 620.0
HKD2_k127_2658798_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 519.0
HKD2_k127_2658798_2 Protein of unknown function (DUF502) - - - 0.00000003915 64.0
HKD2_k127_2669401_0 beta-galactosidase activity - - - 7.424e-212 665.0
HKD2_k127_2669401_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 561.0
HKD2_k127_2669401_10 HEAT repeat - - - 0.0000002149 64.0
HKD2_k127_2669401_11 lipolytic protein G-D-S-L family - - - 0.00007083 56.0
HKD2_k127_2669401_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 552.0
HKD2_k127_2669401_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 504.0
HKD2_k127_2669401_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 499.0
HKD2_k127_2669401_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 453.0
HKD2_k127_2669401_6 Phosphofructokinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 407.0
HKD2_k127_2669401_7 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 432.0
HKD2_k127_2669401_8 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000004445 244.0
HKD2_k127_2669401_9 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000001526 133.0
HKD2_k127_2696442_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 555.0
HKD2_k127_2696442_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 488.0
HKD2_k127_2696442_10 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000001831 188.0
HKD2_k127_2696442_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000001174 142.0
HKD2_k127_2696442_12 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000000002339 139.0
HKD2_k127_2696442_13 Fibronectin-binding A domain protein - - - 0.0000000000000000000000000000000008452 150.0
HKD2_k127_2696442_14 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000001024 134.0
HKD2_k127_2696442_15 Tetratricopeptide repeats - - - 0.000000000000000000000000000004371 137.0
HKD2_k127_2696442_16 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000008765 119.0
HKD2_k127_2696442_17 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001589 105.0
HKD2_k127_2696442_18 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000004993 106.0
HKD2_k127_2696442_19 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000001727 109.0
HKD2_k127_2696442_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 347.0
HKD2_k127_2696442_20 Belongs to the UPF0109 family K06960 - - 0.0000000001037 68.0
HKD2_k127_2696442_21 RDD family - - - 0.00000007624 63.0
HKD2_k127_2696442_22 Roadblock/LC7 domain - - - 0.0000001357 57.0
HKD2_k127_2696442_23 repeat-containing protein - - - 0.000008869 59.0
HKD2_k127_2696442_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 317.0
HKD2_k127_2696442_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 312.0
HKD2_k127_2696442_5 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 332.0
HKD2_k127_2696442_6 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 306.0
HKD2_k127_2696442_7 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003817 284.0
HKD2_k127_2696442_8 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000002876 248.0
HKD2_k127_2696442_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000001861 188.0
HKD2_k127_2736861_0 PfkB domain protein K00874 - 2.7.1.45 1.242e-194 611.0
HKD2_k127_2736861_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 627.0
HKD2_k127_2736861_2 tagaturonate epimerase K21619 - 5.1.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 586.0
HKD2_k127_2736861_3 lactate racemase activity K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 510.0
HKD2_k127_2736861_4 Methane oxygenase PmoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 375.0
HKD2_k127_2736861_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001825 240.0
HKD2_k127_2736861_6 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000003045 154.0
HKD2_k127_2736861_7 FCD K05799 - - 0.0000000000000000000000005763 119.0
HKD2_k127_2764879_0 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001919 246.0
HKD2_k127_2764879_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
HKD2_k127_2764879_2 Putative regulatory protein - - - 0.00000000000000000000000000000000000000000000000000007747 191.0
HKD2_k127_2764879_3 - - - - 0.0000000000000000000000000000000000000000000000003952 182.0
HKD2_k127_2764879_4 PFAM Band 7 protein - - - 0.00000000000000000000000000000000003861 136.0
HKD2_k127_2811489_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5.575e-312 975.0
HKD2_k127_2811489_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 544.0
HKD2_k127_2811489_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 469.0
HKD2_k127_2811489_3 recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002183 280.0
HKD2_k127_2811489_4 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
HKD2_k127_2811489_5 PHP domain protein - - - 0.0000000000000000000000000000000000000001338 170.0
HKD2_k127_2811489_6 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000000008473 102.0
HKD2_k127_2811489_7 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000004049 90.0
HKD2_k127_2811489_8 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000001573 67.0
HKD2_k127_2811489_9 - - - - 0.0001582 55.0
HKD2_k127_285803_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 8.109e-211 666.0
HKD2_k127_285803_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 436.0
HKD2_k127_285803_10 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000005084 136.0
HKD2_k127_285803_11 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000002011 147.0
HKD2_k127_285803_12 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000002887 150.0
HKD2_k127_285803_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000001045 112.0
HKD2_k127_285803_14 Helix-hairpin-helix motif - - - 0.0000000000000000000003795 101.0
HKD2_k127_285803_15 Alpha beta K06889 - - 0.0000000000000000001424 94.0
HKD2_k127_285803_16 - - - - 0.00002341 55.0
HKD2_k127_285803_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 374.0
HKD2_k127_285803_3 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 328.0
HKD2_k127_285803_4 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 331.0
HKD2_k127_285803_5 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 319.0
HKD2_k127_285803_6 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000002014 219.0
HKD2_k127_285803_7 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000000008662 164.0
HKD2_k127_285803_8 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000001391 163.0
HKD2_k127_285803_9 belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.0000000000000000000000000000000000000003898 154.0
HKD2_k127_2937441_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002482 285.0
HKD2_k127_2937441_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000003414 123.0
HKD2_k127_2937441_2 Forkhead associated domain - - - 0.0000001011 60.0
HKD2_k127_2948848_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.157e-204 649.0
HKD2_k127_2948848_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 326.0
HKD2_k127_2948848_2 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001864 243.0
HKD2_k127_2948848_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000002829 211.0
HKD2_k127_2948848_4 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000223 185.0
HKD2_k127_2948848_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000453 169.0
HKD2_k127_2948848_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000004758 170.0
HKD2_k127_2948848_7 peptidase M48, Ste24p - - - 0.000000000000000002373 101.0
HKD2_k127_3001143_0 Sortilin, neurotensin receptor 3, - - - 0.0 1241.0
HKD2_k127_3001143_1 - - - - 4.32e-248 817.0
HKD2_k127_3001143_2 PAP2 superfamily - - - 4.355e-208 658.0
HKD2_k127_3001143_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 501.0
HKD2_k127_3001143_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002637 280.0
HKD2_k127_3001143_5 PFAM Pyrrolo-quinoline quinone K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000007032 190.0
HKD2_k127_3001143_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000002211 187.0
HKD2_k127_3001143_7 toxin-antitoxin pair type II binding - - - 0.0000003872 55.0
HKD2_k127_3038665_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002338 247.0
HKD2_k127_3038665_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000001061 210.0
HKD2_k127_3038665_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000004601 138.0
HKD2_k127_3038665_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.0000000001116 72.0
HKD2_k127_3064733_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 344.0
HKD2_k127_3064733_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000008811 238.0
HKD2_k127_3064733_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000005633 209.0
HKD2_k127_3064733_3 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000007737 142.0
HKD2_k127_3064733_4 Protein of unknown function (DUF420) - - - 0.000000000000000000000000000008366 134.0
HKD2_k127_3064733_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000228 97.0
HKD2_k127_3064733_6 COG1520 FOG WD40-like repeat - - - 0.000000000003151 78.0
HKD2_k127_3064733_7 Protein of unknown function (DUF465) - - - 0.000004037 52.0
HKD2_k127_3097843_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 512.0
HKD2_k127_3097843_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000176 252.0
HKD2_k127_3097843_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004971 265.0
HKD2_k127_3097843_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003852 253.0
HKD2_k127_3097843_4 Domain of unknown function (DUF4380) - - - 0.00000000000000000000000000000000000000000000003934 185.0
HKD2_k127_3097843_5 Thioredoxin-like - - - 0.000000000000000000000000000000001476 137.0
HKD2_k127_3097843_6 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.00000000000000000000000003387 113.0
HKD2_k127_3097843_7 Lactoylglutathione lyase K05606 - 5.1.99.1 0.00000000000009709 83.0
HKD2_k127_3097843_8 - - - - 0.000000000448 69.0
HKD2_k127_3097843_9 ATP-independent chaperone mediated protein folding K06006 - - 0.0005593 49.0
HKD2_k127_3133484_0 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 456.0
HKD2_k127_3133484_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 379.0
HKD2_k127_3133484_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 351.0
HKD2_k127_3133484_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 321.0
HKD2_k127_3133484_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 268.0
HKD2_k127_3133484_5 MacB-like periplasmic core domain K02003,K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008261 269.0
HKD2_k127_3133484_6 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003566 256.0
HKD2_k127_3133484_7 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000006791 177.0
HKD2_k127_3133484_8 PFAM Dual specificity protein phosphatase - - - 0.0000000004339 66.0
HKD2_k127_318682_0 Class II Aldolase and Adducin N-terminal domain - - - 2.675e-291 913.0
HKD2_k127_318682_2 isomerase K01820 - 5.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 591.0
HKD2_k127_318682_3 COG1070 Sugar (pentulose and hexulose) K00848 - 2.7.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 409.0
HKD2_k127_318682_4 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000006777 246.0
HKD2_k127_318682_5 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000000000000000000000000004733 203.0
HKD2_k127_318682_6 YceI-like domain - - - 0.0000000000000005319 87.0
HKD2_k127_319138_0 AcrB/AcrD/AcrF family - - - 0.0 1050.0
HKD2_k127_319138_1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 5.677e-303 953.0
HKD2_k127_319138_2 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 359.0
HKD2_k127_319138_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003648 251.0
HKD2_k127_319138_4 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000001723 149.0
HKD2_k127_3193549_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1246.0
HKD2_k127_3193549_1 Belongs to the glycosyl hydrolase 2 family - - - 0.0 1186.0
HKD2_k127_3193549_10 Sigma-70, region 4 K03088 - - 0.0000000000000000000001692 106.0
HKD2_k127_3193549_11 Cytochrome C' - - - 0.000000000000000004264 94.0
HKD2_k127_3193549_12 - - - - 0.00001174 55.0
HKD2_k127_3193549_14 Double zinc ribbon - - - 0.00002612 57.0
HKD2_k127_3193549_15 denitrification pathway K03532 - - 0.000179 51.0
HKD2_k127_3193549_16 AntiSigma factor - - - 0.0009606 50.0
HKD2_k127_3193549_2 Sodium:solute symporter family - - - 1.46e-286 891.0
HKD2_k127_3193549_3 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 611.0
HKD2_k127_3193549_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 405.0
HKD2_k127_3193549_5 KR domain K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001784 314.0
HKD2_k127_3193549_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000008997 250.0
HKD2_k127_3193549_7 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000005871 164.0
HKD2_k127_3193549_8 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000006426 152.0
HKD2_k127_3193549_9 - - - - 0.0000000000000000000000000005525 127.0
HKD2_k127_3213614_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate K03701 - - 0.0 1122.0
HKD2_k127_3213614_1 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 546.0
HKD2_k127_3213614_10 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000005023 145.0
HKD2_k127_3213614_11 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8 0.000000000000000000000000000000000008191 154.0
HKD2_k127_3213614_12 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.0000000000000000000000000000007299 142.0
HKD2_k127_3213614_13 Heat shock protein DnaJ domain protein - - - 0.0000000000000189 85.0
HKD2_k127_3213614_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 450.0
HKD2_k127_3213614_3 Belongs to the ALAD family K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 439.0
HKD2_k127_3213614_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 418.0
HKD2_k127_3213614_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 360.0
HKD2_k127_3213614_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000001114 276.0
HKD2_k127_3213614_7 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000002284 203.0
HKD2_k127_3213614_8 TilS substrate binding domain K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000002407 193.0
HKD2_k127_3213614_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000001512 182.0
HKD2_k127_3214054_0 Glycosyl hydrolase family 3 K05349 - 3.2.1.21 2.023e-303 958.0
HKD2_k127_3214054_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 453.0
HKD2_k127_3214054_2 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 334.0
HKD2_k127_3214054_3 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.00000000007555 72.0
HKD2_k127_3214054_4 chlorophyll binding - - - 0.00009669 54.0
HKD2_k127_3249444_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 1.552e-208 679.0
HKD2_k127_3249444_1 Domain of unknown function (DUF5107) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 462.0
HKD2_k127_3249444_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000003442 87.0
HKD2_k127_3249444_3 - - - - 0.00005449 52.0
HKD2_k127_3288574_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000004599 196.0
HKD2_k127_3288574_1 Belongs to the complex I 20 kDa subunit family K18023 - 1.12.7.2 0.00000000000000000000000000000000004629 151.0
HKD2_k127_3288574_2 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000002519 121.0
HKD2_k127_3288574_3 peptidyl-tyrosine sulfation - - - 0.0000000000000001162 92.0
HKD2_k127_3338020_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 482.0
HKD2_k127_3338020_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 444.0
HKD2_k127_3338020_2 Acetyltransferase (GNAT) domain K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 462.0
HKD2_k127_3338020_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 370.0
HKD2_k127_3338020_4 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 347.0
HKD2_k127_3338020_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000001846 205.0
HKD2_k127_3338020_6 TonB-dependent receptor K16092 - - 0.00000000000000000000000001566 122.0
HKD2_k127_3339158_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 603.0
HKD2_k127_3346206_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 349.0
HKD2_k127_3346206_1 rubredoxin K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 313.0
HKD2_k127_3346206_10 Putative phosphatase (DUF442) - - - 0.0000000000000000001834 103.0
HKD2_k127_3346206_11 redox protein, regulator of disulfide bond formation K07397 - - 0.00000001055 57.0
HKD2_k127_3346206_12 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000023 65.0
HKD2_k127_3346206_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 299.0
HKD2_k127_3346206_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001364 280.0
HKD2_k127_3346206_4 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008599 275.0
HKD2_k127_3346206_5 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000005481 252.0
HKD2_k127_3346206_6 RelA SpoT domain protein - - - 0.0000000000000000000000000000000000000000000000000001109 206.0
HKD2_k127_3346206_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000008897 201.0
HKD2_k127_3346206_8 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000002074 150.0
HKD2_k127_3346206_9 Proto-chlorophyllide reductase 57 kd subunit - - - 0.000000000000000000004147 101.0
HKD2_k127_3359035_0 belongs to the thioredoxin family K03671,K05838 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 493.0
HKD2_k127_3359035_1 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 486.0
HKD2_k127_3359035_10 - - - - 0.00000000006435 75.0
HKD2_k127_3359035_11 His Kinase A (phosphoacceptor) domain - - - 0.000000002482 66.0
HKD2_k127_3359035_2 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 402.0
HKD2_k127_3359035_3 synthase K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 314.0
HKD2_k127_3359035_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002246 279.0
HKD2_k127_3359035_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003222 272.0
HKD2_k127_3359035_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000002399 193.0
HKD2_k127_3359035_7 PFAM Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000002439 163.0
HKD2_k127_3359035_8 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000008766 165.0
HKD2_k127_3359035_9 AI-2E family transporter - - - 0.0000000000000000000000000000000000001936 150.0
HKD2_k127_3400830_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 344.0
HKD2_k127_3400830_1 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 313.0
HKD2_k127_3400830_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001004 270.0
HKD2_k127_3400830_3 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000002587 240.0
HKD2_k127_3400830_4 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000005001 239.0
HKD2_k127_3400830_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000003532 224.0
HKD2_k127_3400830_6 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000006815 193.0
HKD2_k127_34081_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1893.0
HKD2_k127_34081_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 343.0
HKD2_k127_34081_2 Surface antigen K07278 - - 0.0009779 51.0
HKD2_k127_3435892_0 Heat shock 70 kDa protein K04043 - - 1.564e-209 673.0
HKD2_k127_3435892_1 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 411.0
HKD2_k127_3435892_2 Phosphate acetyl/butaryl transferase K00625,K02028 - 2.3.1.8,3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 293.0
HKD2_k127_3435892_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004275 302.0
HKD2_k127_3435892_4 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000008841 161.0
HKD2_k127_3435892_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000003789 160.0
HKD2_k127_3435892_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000002835 100.0
HKD2_k127_346025_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 563.0
HKD2_k127_346025_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 556.0
HKD2_k127_346025_10 Transposase K07491 - - 0.000000000000000000000000003115 119.0
HKD2_k127_346025_11 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000001466 88.0
HKD2_k127_346025_12 membrane-fusion protein - - - 0.000000000000003345 88.0
HKD2_k127_346025_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 387.0
HKD2_k127_346025_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 349.0
HKD2_k127_346025_4 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 370.0
HKD2_k127_346025_5 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 349.0
HKD2_k127_346025_6 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001129 285.0
HKD2_k127_346025_7 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000002944 240.0
HKD2_k127_346025_8 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000009433 190.0
HKD2_k127_346025_9 HlyD family secretion protein K02005 - - 0.0000000000000000000000000005988 128.0
HKD2_k127_3513284_0 Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 473.0
HKD2_k127_3513284_1 PFAM glucosamine galactosamine-6-phosphate isomerase K02564 - 3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 309.0
HKD2_k127_3513284_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001101 278.0
HKD2_k127_3513284_3 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000006193 190.0
HKD2_k127_3513284_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000003581 171.0
HKD2_k127_3571296_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 407.0
HKD2_k127_3571296_1 N-acyl-L-amino acid amidohydrolase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 388.0
HKD2_k127_3571296_2 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002533 266.0
HKD2_k127_3571296_3 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000001286 203.0
HKD2_k127_3571296_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000001342 160.0
HKD2_k127_3571296_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000001588 153.0
HKD2_k127_3571296_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000003665 136.0
HKD2_k127_3571296_7 von Willebrand factor, type A K12511 - - 0.000000000000000000008082 103.0
HKD2_k127_3594606_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 5.047e-259 817.0
HKD2_k127_3594606_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 1.853e-244 777.0
HKD2_k127_3594606_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 460.0
HKD2_k127_3594606_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 341.0
HKD2_k127_3594606_4 Flavin-nucleotide-binding protein K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008536 249.0
HKD2_k127_3594606_5 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000003923 114.0
HKD2_k127_3594606_6 NmrA-like family - - - 0.0000000006496 64.0
HKD2_k127_3718531_0 B12 binding domain K00548 - 2.1.1.13 0.0 1538.0
HKD2_k127_3718531_1 Belongs to the ClpA ClpB family K03694 - - 9.823e-255 811.0
HKD2_k127_3718531_2 ATP:ADP antiporter activity K01932,K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 356.0
HKD2_k127_3718531_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001439 295.0
HKD2_k127_3718531_4 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.00000000000000000000000000001254 120.0
HKD2_k127_3718531_5 - - - - 0.00000000000000000000000005838 127.0
HKD2_k127_3718531_6 Smr domain - - - 0.00000000000000000000000459 112.0
HKD2_k127_3739425_0 Oligopeptide transporter OPT - - - 1.171e-246 780.0
HKD2_k127_3739425_1 Fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 612.0
HKD2_k127_3739425_10 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 340.0
HKD2_k127_3739425_11 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 302.0
HKD2_k127_3739425_12 unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 316.0
HKD2_k127_3739425_13 PFAM response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 298.0
HKD2_k127_3739425_14 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002957 294.0
HKD2_k127_3739425_15 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001404 263.0
HKD2_k127_3739425_16 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003561 260.0
HKD2_k127_3739425_17 histidyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000005096 202.0
HKD2_k127_3739425_18 Protein of unknown function (DUF1572) - - - 0.00000000000000000000000000000000000000000000001856 189.0
HKD2_k127_3739425_19 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000001061 170.0
HKD2_k127_3739425_2 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 536.0
HKD2_k127_3739425_20 Stringent starvation protein B K09985 - - 0.0000000000000000000000000000000000000003232 158.0
HKD2_k127_3739425_21 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000003357 153.0
HKD2_k127_3739425_22 PFAM phosphoesterase, PA-phosphatase related - - - 0.000000000000000000008173 105.0
HKD2_k127_3739425_23 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000001181 104.0
HKD2_k127_3739425_24 ABC transporter transmembrane region K06147 - - 0.000946 51.0
HKD2_k127_3739425_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 535.0
HKD2_k127_3739425_4 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 552.0
HKD2_k127_3739425_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 473.0
HKD2_k127_3739425_6 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 456.0
HKD2_k127_3739425_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 441.0
HKD2_k127_3739425_8 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 428.0
HKD2_k127_3739425_9 Glycosyl Hydrolase Family 88 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 360.0
HKD2_k127_3832731_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 413.0
HKD2_k127_3832731_1 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 365.0
HKD2_k127_3832731_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 308.0
HKD2_k127_3832731_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 311.0
HKD2_k127_3832731_4 - - - - 0.0000000000000000000000000000000000000000000000000000003481 206.0
HKD2_k127_3832731_5 Domain of unknown function (DUF5009) - - - 0.00000000000000000000000000000000000000000000000003331 203.0
HKD2_k127_3832731_6 Glycosyl hydrolase-like 10 - - - 0.0002645 52.0
HKD2_k127_3832731_7 TonB-dependent Receptor Plug Domain - - - 0.0002798 43.0
HKD2_k127_3836471_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 584.0
HKD2_k127_3836471_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 584.0
HKD2_k127_3836471_10 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000004021 157.0
HKD2_k127_3836471_11 Protein of unknown function (DUF2585) - - - 0.0000000000000000000000000000004935 138.0
HKD2_k127_3836471_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 433.0
HKD2_k127_3836471_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 330.0
HKD2_k127_3836471_4 Squalene/phytoene synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002354 247.0
HKD2_k127_3836471_5 Fumarylacetoacetate (FAA) hydrolase family K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000009997 258.0
HKD2_k127_3836471_6 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005611 235.0
HKD2_k127_3836471_7 phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000006116 224.0
HKD2_k127_3836471_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000901 203.0
HKD2_k127_3836471_9 FAD dependent oxidoreductase K00514 - 1.3.5.6 0.000000000000000000000000000000000000000000000000004807 204.0
HKD2_k127_3836481_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 5.066e-240 760.0
HKD2_k127_3836481_1 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 567.0
HKD2_k127_3836481_11 Protein of unknown function (DUF2892) - - - 0.0000000000000000004385 89.0
HKD2_k127_3836481_12 TIGRFAM TonB K03832 - - 0.000000000000000002838 93.0
HKD2_k127_3836481_14 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00004951 57.0
HKD2_k127_3836481_2 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 526.0
HKD2_k127_3836481_3 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000002197 265.0
HKD2_k127_3836481_4 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000001735 213.0
HKD2_k127_3836481_5 Lysophospholipase K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000006969 196.0
HKD2_k127_3836481_6 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000001599 170.0
HKD2_k127_3836481_7 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000004274 155.0
HKD2_k127_3836481_8 - - - - 0.0000000000000000000000000000000001513 152.0
HKD2_k127_3836481_9 Cytidylate kinase-like family - - - 0.000000000000000000000000000000002274 149.0
HKD2_k127_3902110_0 Tricorn protease C1 domain K08676 - - 0.0 1255.0
HKD2_k127_3902110_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1075.0
HKD2_k127_3902110_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K16950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 387.0
HKD2_k127_3902110_11 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 336.0
HKD2_k127_3902110_12 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 338.0
HKD2_k127_3902110_13 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 341.0
HKD2_k127_3902110_14 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 319.0
HKD2_k127_3902110_15 electron transfer activity K03616,K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 300.0
HKD2_k127_3902110_16 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001282 297.0
HKD2_k127_3902110_17 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000002883 254.0
HKD2_k127_3902110_18 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000002385 205.0
HKD2_k127_3902110_19 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000001868 200.0
HKD2_k127_3902110_2 xanthine dehydrogenase activity - - - 2.098e-307 977.0
HKD2_k127_3902110_20 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000005594 174.0
HKD2_k127_3902110_21 Antirepressor regulating drug resistance - - - 0.000000000000000000000000000000000009623 156.0
HKD2_k127_3902110_22 Penicillinase repressor - - - 0.0000000000000000000000000000000006199 135.0
HKD2_k127_3902110_23 Dehydrogenase K00087,K03518 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000003646 139.0
HKD2_k127_3902110_24 Belongs to the universal stress protein A family - - - 0.000000000000000000000000003298 123.0
HKD2_k127_3902110_25 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000003295 104.0
HKD2_k127_3902110_26 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000003275 70.0
HKD2_k127_3902110_3 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 2.162e-252 803.0
HKD2_k127_3902110_4 Protein of unknown function (DUF4038) - - - 2.007e-221 710.0
HKD2_k127_3902110_5 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00207,K12527,K17723 - 1.3.1.1,1.3.1.2,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 609.0
HKD2_k127_3902110_6 dipeptidyl-peptidase activity K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 592.0
HKD2_k127_3902110_8 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 511.0
HKD2_k127_3902110_9 2 iron, 2 sulfur cluster binding K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 465.0
HKD2_k127_3903470_0 Belongs to the glycosyl hydrolase 3 family K05349,K17641 - 3.2.1.21 1.786e-213 692.0
HKD2_k127_3903470_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.41e-197 639.0
HKD2_k127_3903470_10 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000004443 171.0
HKD2_k127_3903470_11 3D domain - - - 0.000000000000006162 81.0
HKD2_k127_3903470_12 - - - - 0.00000000004635 69.0
HKD2_k127_3903470_13 PFAM glycosyl transferase family 39 K14340 - - 0.000000000129 74.0
HKD2_k127_3903470_2 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 518.0
HKD2_k127_3903470_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 302.0
HKD2_k127_3903470_4 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000127 274.0
HKD2_k127_3903470_5 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006435 254.0
HKD2_k127_3903470_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000005598 231.0
HKD2_k127_3903470_7 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.0000000000000000000000000000000000000000000000000000000681 201.0
HKD2_k127_3903470_8 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000004447 193.0
HKD2_k127_3903470_9 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000001492 177.0
HKD2_k127_3918206_0 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002047 239.0
HKD2_k127_3918206_1 Thioesterase K07107 - - 0.0000000000000000000000000000000008739 133.0
HKD2_k127_3918206_2 ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000001651 108.0
HKD2_k127_3918206_3 Probably functions as a manganese efflux pump - - - 0.0000001643 65.0
HKD2_k127_3947808_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1048.0
HKD2_k127_3947808_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 454.0
HKD2_k127_3947808_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000005058 241.0
HKD2_k127_3947808_3 Tetratricopeptide repeat - - - 0.00000000000885 72.0
HKD2_k127_3953635_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.354e-308 976.0
HKD2_k127_3953635_1 FAD linked oxidases, C-terminal domain K18930 - - 4.322e-235 766.0
HKD2_k127_3953635_10 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000002434 178.0
HKD2_k127_3953635_11 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000002656 151.0
HKD2_k127_3953635_12 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000002694 138.0
HKD2_k127_3953635_13 AcrB/AcrD/AcrF family K03296 - - 0.0000000000000000000000000000002432 139.0
HKD2_k127_3953635_14 SNARE associated Golgi protein - - - 0.000000000000000000000000000001611 128.0
HKD2_k127_3953635_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000003746 106.0
HKD2_k127_3953635_16 Biotin-lipoyl like - - - 0.0000000000000000000002049 111.0
HKD2_k127_3953635_17 Tetratricopeptide repeat - - - 0.0000000000002986 84.0
HKD2_k127_3953635_18 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.00001536 55.0
HKD2_k127_3953635_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 523.0
HKD2_k127_3953635_3 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 492.0
HKD2_k127_3953635_4 RNA binding S1 domain protein K06959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 428.0
HKD2_k127_3953635_5 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 350.0
HKD2_k127_3953635_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003332 280.0
HKD2_k127_3953635_7 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000002775 237.0
HKD2_k127_3953635_8 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000008384 173.0
HKD2_k127_3953635_9 Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000004298 177.0
HKD2_k127_3963024_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 487.0
HKD2_k127_3963024_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 362.0
HKD2_k127_3963024_2 PFAM UvrB UvrC protein K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006061 274.0
HKD2_k127_3963024_3 4 iron, 4 sulfur cluster binding K00184 - - 0.000000000000000000000000000000000000000000000000000000003015 210.0
HKD2_k127_3963024_4 Doxx family K15977 - - 0.000000000000000000000000000000000000001274 153.0
HKD2_k127_3963024_5 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000008699 72.0
HKD2_k127_4004386_0 Glycosyl hydrolases family 2, TIM barrel domain K01190,K01195 GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23,3.2.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 550.0
HKD2_k127_4004386_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 499.0
HKD2_k127_4004386_2 glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich K01190 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 459.0
HKD2_k127_4004386_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002221 237.0
HKD2_k127_4004386_4 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000006112 192.0
HKD2_k127_4004386_5 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000005133 170.0
HKD2_k127_4004386_6 Polysaccharide deacetylase - - - 0.00000000000000000000000001774 127.0
HKD2_k127_400563_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.509e-225 723.0
HKD2_k127_400563_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 361.0
HKD2_k127_400563_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 328.0
HKD2_k127_400563_3 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 330.0
HKD2_k127_400563_4 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000008702 267.0
HKD2_k127_400563_5 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000006887 168.0
HKD2_k127_400563_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000003673 149.0
HKD2_k127_400563_7 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000002954 141.0
HKD2_k127_400563_8 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000009276 121.0
HKD2_k127_4016489_0 Beta-galactosidase K01190 - 3.2.1.23 5e-324 1042.0
HKD2_k127_4016489_1 PFAM ABC transporter transmembrane K06147 - - 1.41e-268 837.0
HKD2_k127_4016489_10 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000000001785 158.0
HKD2_k127_4016489_11 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000001859 153.0
HKD2_k127_4016489_12 - - - - 0.0000000000000000000000000000008087 139.0
HKD2_k127_4016489_13 BON domain - - - 0.00000000000000000000131 105.0
HKD2_k127_4016489_14 DoxX-like family K15977 - - 0.00000000000000005277 92.0
HKD2_k127_4016489_15 Rhomboid family - - - 0.00000000000004535 79.0
HKD2_k127_4016489_16 Cyclic nucleotide-monophosphate binding domain - - - 0.000000195 59.0
HKD2_k127_4016489_2 WD40-like Beta Propeller Repeat - - - 4.98e-203 645.0
HKD2_k127_4016489_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 502.0
HKD2_k127_4016489_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 396.0
HKD2_k127_4016489_5 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 338.0
HKD2_k127_4016489_6 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 325.0
HKD2_k127_4016489_7 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001045 291.0
HKD2_k127_4016489_8 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001491 259.0
HKD2_k127_4016489_9 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000003711 227.0
HKD2_k127_4035502_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 383.0
HKD2_k127_4035502_1 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
HKD2_k127_4035502_2 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000002785 248.0
HKD2_k127_4035502_3 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000712 235.0
HKD2_k127_4035502_4 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000002951 192.0
HKD2_k127_4035502_5 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000005037 139.0
HKD2_k127_4035502_6 4Fe-4S binding domain - - - 0.000000000000000000000000003267 126.0
HKD2_k127_4038350_0 AMP-binding enzyme C-terminal domain K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 539.0
HKD2_k127_4038350_1 alpha-galactosidase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 545.0
HKD2_k127_4038350_10 CoA binding domain K06929 - - 0.00000000000000000000000000000000000009893 147.0
HKD2_k127_4038350_11 - - - - 0.000000000005162 72.0
HKD2_k127_4038350_12 Prolyl oligopeptidase family - - - 0.00000791 55.0
HKD2_k127_4038350_2 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 523.0
HKD2_k127_4038350_3 GHMP kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 408.0
HKD2_k127_4038350_4 KDPG and KHG aldolase K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 315.0
HKD2_k127_4038350_5 Inosine-uridine preferring nucleoside hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 317.0
HKD2_k127_4038350_6 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 311.0
HKD2_k127_4038350_7 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 292.0
HKD2_k127_4038350_8 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001593 271.0
HKD2_k127_4038350_9 - - - - 0.0000000000000000000000000000000000000000508 163.0
HKD2_k127_4052917_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 388.0
HKD2_k127_4052917_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 336.0
HKD2_k127_4052917_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000002036 113.0
HKD2_k127_4052917_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000003844 55.0
HKD2_k127_4061774_0 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 434.0
HKD2_k127_4061774_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 435.0
HKD2_k127_4061774_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 399.0
HKD2_k127_4061774_3 Methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 368.0
HKD2_k127_4061774_4 4-phosphoerythronate dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 334.0
HKD2_k127_4061774_5 oxidoreductase activity - - - 0.00000000000002474 88.0
HKD2_k127_4061774_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00008546 55.0
HKD2_k127_4213923_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.0 1219.0
HKD2_k127_4213923_1 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 555.0
HKD2_k127_4213923_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 473.0
HKD2_k127_4213923_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 390.0
HKD2_k127_4213923_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 358.0
HKD2_k127_4213923_5 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000001776 120.0
HKD2_k127_4213923_6 Protein of unknown function (DUF2911) - - - 0.000000000000000000000004371 109.0
HKD2_k127_4213923_7 PFAM von Willebrand factor type A K07114,K12511 - - 0.000000000000000000000201 111.0
HKD2_k127_426089_0 Zinc carboxypeptidase - - - 4.959e-206 667.0
HKD2_k127_426089_1 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 547.0
HKD2_k127_426089_2 Belongs to the DEAD box helicase family K03732,K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 337.0
HKD2_k127_426089_3 ABC transporter C-terminal domain K06158 - - 0.000000000000000000000001781 110.0
HKD2_k127_426089_4 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000003711 76.0
HKD2_k127_4273151_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 288.0
HKD2_k127_4273151_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001233 284.0
HKD2_k127_4273151_2 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000004645 165.0
HKD2_k127_4273151_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000005305 154.0
HKD2_k127_4273151_4 Competence protein - - - 0.0000000000000000000000000000000003563 140.0
HKD2_k127_4273151_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000007347 115.0
HKD2_k127_4273151_6 S1 P1 Nuclease - - - 0.00000000000000000000000177 120.0
HKD2_k127_4273151_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000008846 109.0
HKD2_k127_4273151_8 STAS domain K04749 - - 0.0000000000001311 80.0
HKD2_k127_4273151_9 Protein of unknown function (DUF1573) - - - 0.00000007624 63.0
HKD2_k127_4303968_0 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 4.609e-210 670.0
HKD2_k127_4303968_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000009469 219.0
HKD2_k127_4303968_2 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000001763 131.0
HKD2_k127_444126_0 Alpha-glucosidase K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 588.0
HKD2_k127_444126_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 470.0
HKD2_k127_444126_10 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000007156 154.0
HKD2_k127_444126_11 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000002062 138.0
HKD2_k127_444126_12 Thioredoxin K03671 - - 0.00000000000000000000000000000008392 142.0
HKD2_k127_444126_13 phosphoesterase, PA-phosphatase - - - 0.00000000000000000005933 103.0
HKD2_k127_444126_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 409.0
HKD2_k127_444126_3 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 379.0
HKD2_k127_444126_4 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 318.0
HKD2_k127_444126_5 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 294.0
HKD2_k127_444126_6 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 293.0
HKD2_k127_444126_7 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001401 275.0
HKD2_k127_444126_8 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005908 258.0
HKD2_k127_444126_9 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002226 265.0
HKD2_k127_4480420_0 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 567.0
HKD2_k127_4480420_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 447.0
HKD2_k127_4480420_2 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003571 281.0
HKD2_k127_4480420_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000001554 223.0
HKD2_k127_4480420_4 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000009021 104.0
HKD2_k127_4480420_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000009896 111.0
HKD2_k127_4480420_6 Forkhead associated domain - - - 0.0000000000001653 81.0
HKD2_k127_4570483_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 531.0
HKD2_k127_4570483_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 408.0
HKD2_k127_4570483_2 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
HKD2_k127_4570483_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000009862 245.0
HKD2_k127_4570483_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000856 216.0
HKD2_k127_4570483_5 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000006588 165.0
HKD2_k127_4570483_6 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000004362 57.0
HKD2_k127_4582071_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1081.0
HKD2_k127_4582071_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 521.0
HKD2_k127_4582071_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000002824 128.0
HKD2_k127_4582071_11 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000751 113.0
HKD2_k127_4582071_12 Heat shock protein DnaJ domain protein - - - 0.0000000000000000001607 101.0
HKD2_k127_4582071_13 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000004602 94.0
HKD2_k127_4582071_14 Outer membrane protein (OmpH-like) K06142 - - 0.00000001895 63.0
HKD2_k127_4582071_15 TonB C terminal - - - 0.00002576 56.0
HKD2_k127_4582071_2 Surface antigen variable number K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 415.0
HKD2_k127_4582071_3 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 337.0
HKD2_k127_4582071_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 314.0
HKD2_k127_4582071_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008893 274.0
HKD2_k127_4582071_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000005692 262.0
HKD2_k127_4582071_7 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001254 258.0
HKD2_k127_4582071_8 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000196 247.0
HKD2_k127_4582071_9 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000006745 246.0
HKD2_k127_4598811_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.074e-201 675.0
HKD2_k127_4598811_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 537.0
HKD2_k127_4598811_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 311.0
HKD2_k127_4598811_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000002666 247.0
HKD2_k127_4598811_4 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000101 219.0
HKD2_k127_4598811_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000001003 199.0
HKD2_k127_4781623_0 ASPIC and UnbV - - - 7.387e-206 672.0
HKD2_k127_4781623_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 560.0
HKD2_k127_4781623_2 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 490.0
HKD2_k127_4781623_3 histidine kinase A domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 499.0
HKD2_k127_4781623_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 471.0
HKD2_k127_4781623_5 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 364.0
HKD2_k127_4781623_6 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 368.0
HKD2_k127_4781623_7 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000007169 157.0
HKD2_k127_4794449_0 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 590.0
HKD2_k127_4794449_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 576.0
HKD2_k127_4794449_10 4Fe-4S binding domain - - - 0.0000000000000000000000000000007205 123.0
HKD2_k127_4794449_11 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.00000000000000000000000008037 117.0
HKD2_k127_4794449_12 - - - - 0.0000000002967 71.0
HKD2_k127_4794449_2 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 480.0
HKD2_k127_4794449_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 320.0
HKD2_k127_4794449_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003096 277.0
HKD2_k127_4794449_5 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004107 276.0
HKD2_k127_4794449_6 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000001767 200.0
HKD2_k127_4794449_7 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000002102 200.0
HKD2_k127_4794449_8 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000278 193.0
HKD2_k127_4794449_9 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000482 182.0
HKD2_k127_4862201_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 530.0
HKD2_k127_4862201_1 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 331.0
HKD2_k127_4862201_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001613 291.0
HKD2_k127_4862201_3 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000001057 201.0
HKD2_k127_4862201_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000005523 111.0
HKD2_k127_4862201_5 Cell division protein FtsQ K03589 - - 0.0000000000753 76.0
HKD2_k127_487324_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 416.0
HKD2_k127_487324_1 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 401.0
HKD2_k127_487324_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 377.0
HKD2_k127_487324_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003571 261.0
HKD2_k127_487324_4 Aminotransferase K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000005303 230.0
HKD2_k127_487324_5 Sulfatase - - - 0.0000000000000000000000000000000000000000000000002108 198.0
HKD2_k127_487324_6 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000005004 106.0
HKD2_k127_487324_7 PFAM Radical SAM domain protein - - - 0.0000000000000000003205 97.0
HKD2_k127_487324_8 Domain of unknown function (DUF4388) - - - 0.00001306 56.0
HKD2_k127_4877613_0 COG1472 Beta-glucosidase-related glycosidases K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004883 285.0
HKD2_k127_4877613_1 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000002538 244.0
HKD2_k127_4877613_2 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000001295 123.0
HKD2_k127_4877613_3 GatB Yqey family protein K09117 - - 0.0000000000000000000000000003564 119.0
HKD2_k127_4877613_5 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.000000000000000000000007138 118.0
HKD2_k127_4925373_0 4Fe-4S dicluster domain K00184 - - 2.086e-257 818.0
HKD2_k127_4925373_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000001319 135.0
HKD2_k127_4927520_0 PFAM LmbE family protein K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 602.0
HKD2_k127_4927520_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 553.0
HKD2_k127_4927520_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000005455 201.0
HKD2_k127_4927520_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000003037 201.0
HKD2_k127_4927520_12 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000001934 215.0
HKD2_k127_4927520_13 Membrane - - - 0.0000000000000000000000000000002036 141.0
HKD2_k127_4927520_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000003695 139.0
HKD2_k127_4927520_15 Domain of unknown function (DUF4340) - - - 0.0000000000000000006058 101.0
HKD2_k127_4927520_16 Domain of unknown function (DUF4388) - - - 0.000000001354 72.0
HKD2_k127_4927520_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 516.0
HKD2_k127_4927520_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 392.0
HKD2_k127_4927520_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 369.0
HKD2_k127_4927520_5 transport system involved in gliding motility, auxiliary K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 319.0
HKD2_k127_4927520_6 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005028 280.0
HKD2_k127_4927520_7 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004334 271.0
HKD2_k127_4927520_8 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000001239 265.0
HKD2_k127_4927520_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000003103 230.0
HKD2_k127_5145477_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 434.0
HKD2_k127_5145477_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 339.0
HKD2_k127_5145477_2 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 325.0
HKD2_k127_5145477_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000001631 222.0
HKD2_k127_5145477_4 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000008263 198.0
HKD2_k127_5145477_5 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000004313 145.0
HKD2_k127_5166290_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.152e-233 738.0
HKD2_k127_5166290_1 General secretory system II, protein E domain protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 546.0
HKD2_k127_5166290_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 362.0
HKD2_k127_5166290_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000001321 198.0
HKD2_k127_5166290_4 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000007428 169.0
HKD2_k127_5166290_5 phenylalanine-tRNA ligase activity K01890 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000001182 177.0
HKD2_k127_5166290_6 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000003926 167.0
HKD2_k127_5166290_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000007892 135.0
HKD2_k127_5166290_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001561 69.0
HKD2_k127_5184495_1 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003574 250.0
HKD2_k127_5184495_2 sugar isomerase K01820 - 5.3.1.14 0.00000000000000000003166 92.0
HKD2_k127_5184495_3 - - - - 0.0005955 49.0
HKD2_k127_5209578_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.691e-264 824.0
HKD2_k127_5209578_1 GMC oxidoreductase - - - 0.00000000000000000000000000000005561 127.0
HKD2_k127_5209578_2 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000000000000000000000003618 120.0
HKD2_k127_5209578_3 - - - - 0.00000000000000000000000008164 126.0
HKD2_k127_5209578_4 SnoaL-like domain - - - 0.00000000000000000000001585 112.0
HKD2_k127_521900_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 562.0
HKD2_k127_521900_1 TonB-dependent Receptor Plug Domain K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 571.0
HKD2_k127_521900_2 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 381.0
HKD2_k127_521900_3 ABC-2 family transporter protein K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 334.0
HKD2_k127_521900_4 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006087 260.0
HKD2_k127_521900_5 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000097 165.0
HKD2_k127_521900_6 Fasciclin - - - 0.0000000000000000000000001084 115.0
HKD2_k127_5220108_0 Voltage gated chloride channel - - - 2.936e-259 813.0
HKD2_k127_5220108_1 PFAM Glycoside hydrolase, family 2, TIM barrel K01190 - 3.2.1.23 3.553e-195 614.0
HKD2_k127_5220108_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000007863 153.0
HKD2_k127_5220108_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000002659 114.0
HKD2_k127_5220108_12 phosphate ion binding - - - 0.0000000000000003027 84.0
HKD2_k127_5220108_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 595.0
HKD2_k127_5220108_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 591.0
HKD2_k127_5220108_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 436.0
HKD2_k127_5220108_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 376.0
HKD2_k127_5220108_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 398.0
HKD2_k127_5220108_7 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 344.0
HKD2_k127_5220108_8 PFAM peptidase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 311.0
HKD2_k127_5220108_9 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000001628 206.0
HKD2_k127_5224921_0 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 7.919e-228 730.0
HKD2_k127_5224921_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 443.0
HKD2_k127_5224921_2 Aldehyde dehydrogenase K00131 - 1.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008755 278.0
HKD2_k127_5224921_3 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000002323 161.0
HKD2_k127_5291034_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 383.0
HKD2_k127_5291034_1 TrkA-N domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 293.0
HKD2_k127_5291034_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002502 272.0
HKD2_k127_5291034_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000007227 238.0
HKD2_k127_5291034_4 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000001882 209.0
HKD2_k127_5291034_5 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000004886 147.0
HKD2_k127_5291034_6 Cyclic nucleotide binding domain protein - - - 0.000000000000000003202 99.0
HKD2_k127_5322232_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 417.0
HKD2_k127_5322232_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 383.0
HKD2_k127_5322232_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 299.0
HKD2_k127_5322232_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000006353 243.0
HKD2_k127_5322232_4 Formyl transferase K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000001253 231.0
HKD2_k127_5322232_5 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000001914 142.0
HKD2_k127_5322232_6 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000138 100.0
HKD2_k127_5322232_7 PFAM FecR protein - - - 0.000000003113 69.0
HKD2_k127_5322232_9 - K05826 - - 0.00002545 50.0
HKD2_k127_5384949_0 radical SAM domain protein K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 633.0
HKD2_k127_5384949_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 592.0
HKD2_k127_5384949_2 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 557.0
HKD2_k127_5384949_3 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 447.0
HKD2_k127_5384949_4 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000005205 215.0
HKD2_k127_5384949_5 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000001216 183.0
HKD2_k127_5384949_6 Fatty acid K06076 - - 0.0000000000000000000000006607 117.0
HKD2_k127_5395268_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 1.642e-289 904.0
HKD2_k127_5395268_1 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 482.0
HKD2_k127_5395268_2 protein conserved in bacteria K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 372.0
HKD2_k127_5395268_3 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 376.0
HKD2_k127_5395268_4 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 342.0
HKD2_k127_5395268_5 Putative DNA-binding domain - - - 0.0000000000000000008876 98.0
HKD2_k127_5395268_6 - - - - 0.00000002131 62.0
HKD2_k127_5415370_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 3.147e-317 994.0
HKD2_k127_5415370_1 beta-galactosidase activity - - - 4.753e-313 1007.0
HKD2_k127_5415370_10 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000004164 186.0
HKD2_k127_5415370_11 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000254 140.0
HKD2_k127_5415370_12 NUDIX domain - - - 0.00000000000000000000000000000006349 136.0
HKD2_k127_5415370_13 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000007589 145.0
HKD2_k127_5415370_15 cheY-homologous receiver domain - - - 0.000000000000000000000000003098 120.0
HKD2_k127_5415370_16 Protein-disulfide isomerase - - - 0.000000000000000000000000009599 120.0
HKD2_k127_5415370_17 GtrA-like protein K00995 - 2.7.8.5 0.00000000000000000000000005665 117.0
HKD2_k127_5415370_18 ribonuclease BN K07058 - - 0.0000000000000000001229 105.0
HKD2_k127_5415370_19 PspC domain - - - 0.00000000000001186 80.0
HKD2_k127_5415370_2 Belongs to the glycosyl hydrolase 31 family K01811 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.177 1.192e-277 884.0
HKD2_k127_5415370_20 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000002764 76.0
HKD2_k127_5415370_21 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000001519 74.0
HKD2_k127_5415370_22 NUDIX hydrolase - - - 0.00000000002637 73.0
HKD2_k127_5415370_23 Anthranilate N-benzoyltransferase protein K13065 - 2.3.1.133 0.0000000005552 71.0
HKD2_k127_5415370_24 FHA domain - - - 0.000000006189 66.0
HKD2_k127_5415370_25 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000001685 62.0
HKD2_k127_5415370_27 PFAM Protein kinase domain - - - 0.00002772 56.0
HKD2_k127_5415370_3 Glycoside hydrolase family 30 K01201 - 3.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 559.0
HKD2_k127_5415370_4 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 543.0
HKD2_k127_5415370_5 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 520.0
HKD2_k127_5415370_6 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 405.0
HKD2_k127_5415370_7 Glyco_18 K01183 - 3.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 341.0
HKD2_k127_5415370_8 COG3119 Arylsulfatase A K01137 - 3.1.6.14 0.00000000000000000000000000000000000000000000000000000000000000000000007135 274.0
HKD2_k127_5415370_9 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000001452 194.0
HKD2_k127_54812_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 359.0
HKD2_k127_54812_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 317.0
HKD2_k127_54812_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 319.0
HKD2_k127_54812_3 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 300.0
HKD2_k127_54812_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000172 286.0
HKD2_k127_54812_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000007095 267.0
HKD2_k127_54812_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000007352 203.0
HKD2_k127_54812_7 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000009555 133.0
HKD2_k127_54812_8 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000003259 101.0
HKD2_k127_5484664_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1257.0
HKD2_k127_5484664_1 AAA ATPase, central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 509.0
HKD2_k127_5484664_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000004621 233.0
HKD2_k127_5484664_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000007903 163.0
HKD2_k127_5484664_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000008643 156.0
HKD2_k127_5484664_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000004804 139.0
HKD2_k127_5490883_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.464e-274 853.0
HKD2_k127_5490883_1 GMC oxidoreductase - - - 2.919e-203 642.0
HKD2_k127_5490883_10 Uncharacterized conserved protein (DUF2277) - - - 0.000000000000000000000000003339 116.0
HKD2_k127_5490883_11 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000001504 124.0
HKD2_k127_5490883_12 - - - - 0.00000000000000000007224 93.0
HKD2_k127_5490883_13 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000009546 57.0
HKD2_k127_5490883_2 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 422.0
HKD2_k127_5490883_3 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 401.0
HKD2_k127_5490883_4 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 319.0
HKD2_k127_5490883_5 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006507 289.0
HKD2_k127_5490883_7 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000002772 168.0
HKD2_k127_5490883_8 - - - - 0.000000000000000000000000000000000000003922 151.0
HKD2_k127_5490883_9 - - - - 0.0000000000000000000000000008576 123.0
HKD2_k127_5552918_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 4.431e-298 945.0
HKD2_k127_5552918_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 539.0
HKD2_k127_5552918_10 Peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000001195 175.0
HKD2_k127_5552918_11 NmrA family - - - 0.0000000000000000000000000000000003225 142.0
HKD2_k127_5552918_12 ABC transporter K01990 - - 0.000000000000000000000000002622 121.0
HKD2_k127_5552918_13 oxidoreductase activity - - - 0.000000000000000000000009927 119.0
HKD2_k127_5552918_2 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 466.0
HKD2_k127_5552918_3 Zinc metalloprotease (Elastase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 436.0
HKD2_k127_5552918_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 418.0
HKD2_k127_5552918_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 395.0
HKD2_k127_5552918_6 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 327.0
HKD2_k127_5552918_7 ATPases associated with a variety of cellular activities K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001488 269.0
HKD2_k127_5552918_8 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000001104 257.0
HKD2_k127_5552918_9 - - - - 0.0000000000000000000000000000000000000000000000000000000001411 217.0
HKD2_k127_5560479_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003444 267.0
HKD2_k127_5560479_1 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000001235 218.0
HKD2_k127_5564033_0 Domain of unknown function (DUF5107) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 460.0
HKD2_k127_5564033_1 beta-galactosidase activity - - - 0.00000000000009177 83.0
HKD2_k127_5565810_0 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 556.0
HKD2_k127_5565810_1 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 484.0
HKD2_k127_5565810_10 4Fe-4S dicluster domain K05524 - - 0.0000000000000000000000000000000000004565 141.0
HKD2_k127_5565810_11 Transcriptional regulator - - - 0.00000000000000000000000000000554 125.0
HKD2_k127_5565810_12 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000001508 113.0
HKD2_k127_5565810_14 Domain of unknown function (DUF4395) - - - 0.00000001214 63.0
HKD2_k127_5565810_15 Uncharacterized small protein (DUF2292) - - - 0.000207 52.0
HKD2_k127_5565810_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 445.0
HKD2_k127_5565810_3 Binding-protein-dependent transport system inner membrane component K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 387.0
HKD2_k127_5565810_4 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 363.0
HKD2_k127_5565810_5 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 356.0
HKD2_k127_5565810_6 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000918 265.0
HKD2_k127_5565810_7 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000005491 227.0
HKD2_k127_5565810_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000007105 191.0
HKD2_k127_5565810_9 RNA binding S1 domain protein K06959 - - 0.000000000000000000000000000000000000002914 155.0
HKD2_k127_5578176_0 Involved in the tonB-independent uptake of proteins K03641 - - 6.053e-251 806.0
HKD2_k127_5578176_1 xanthan lyase - - - 2.038e-194 622.0
HKD2_k127_5578176_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001662 242.0
HKD2_k127_5578176_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000007161 233.0
HKD2_k127_5578176_12 DoxX-like family - - - 0.00000000000000000000000000000000000000000000000000000000000007196 217.0
HKD2_k127_5578176_13 Polysaccharide lyase family 4, domain II - - - 0.000000000000000000000000000000007785 146.0
HKD2_k127_5578176_14 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000002028 117.0
HKD2_k127_5578176_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000002686 99.0
HKD2_k127_5578176_16 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000003138 77.0
HKD2_k127_5578176_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 619.0
HKD2_k127_5578176_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 423.0
HKD2_k127_5578176_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 344.0
HKD2_k127_5578176_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 329.0
HKD2_k127_5578176_6 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 303.0
HKD2_k127_5578176_7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 314.0
HKD2_k127_5578176_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000675 278.0
HKD2_k127_5578176_9 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007067 234.0
HKD2_k127_5619869_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 332.0
HKD2_k127_5619869_1 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 337.0
HKD2_k127_5619869_2 EamA-like transporter family - - - 0.0000000000000000001298 104.0
HKD2_k127_5619869_3 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.0000006748 61.0
HKD2_k127_5619869_4 AsmA-like C-terminal region K07289 - - 0.0003154 53.0
HKD2_k127_563364_0 cell wall glycoprotein biosynthetic process - - - 7.737e-248 777.0
HKD2_k127_563364_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 526.0
HKD2_k127_563364_2 Glucose-6-phosphate isomerase (GPI) K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 351.0
HKD2_k127_563364_3 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 325.0
HKD2_k127_563364_4 DNA-binding transcription factor activity K02081,K02444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001659 296.0
HKD2_k127_563364_5 oxalate decarboxylase activity K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003907 280.0
HKD2_k127_563364_6 Ferredoxin - - - 0.000000000000000000000000198 111.0
HKD2_k127_5689986_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 554.0
HKD2_k127_5689986_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000001092 266.0
HKD2_k127_5719085_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1261.0
HKD2_k127_5724283_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 7.355e-281 880.0
HKD2_k127_5724283_1 Peptidase S46 - - - 2.078e-212 684.0
HKD2_k127_5724283_10 DinB family - - - 0.0000000000000000000000000000000000000000000000217 179.0
HKD2_k127_5724283_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000004796 135.0
HKD2_k127_5724283_12 - - - - 0.0000000000000000000000000002507 133.0
HKD2_k127_5724283_2 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282,K18008 - 1.12.2.1,1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 433.0
HKD2_k127_5724283_3 PFAM alanine racemase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 321.0
HKD2_k127_5724283_4 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 310.0
HKD2_k127_5724283_5 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 311.0
HKD2_k127_5724283_6 Belongs to the peptidase M48B family K03799 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000723 288.0
HKD2_k127_5724283_7 Acyl- acyl-carrier-protein --UDP-N-acetylglucosamine O-acyltransferase K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
HKD2_k127_5724283_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000003437 209.0
HKD2_k127_5724283_9 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000001058 191.0
HKD2_k127_5814041_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 589.0
HKD2_k127_5814041_1 Spermidine putrescine-binding periplasmic protein K11069,K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 461.0
HKD2_k127_5814041_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000001118 91.0
HKD2_k127_5814041_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000005136 53.0
HKD2_k127_5814041_2 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 413.0
HKD2_k127_5814041_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 389.0
HKD2_k127_5814041_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 334.0
HKD2_k127_5814041_5 - K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009348 306.0
HKD2_k127_5814041_6 Binding-protein-dependent transport system inner membrane component K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005785 270.0
HKD2_k127_5814041_8 Domain of unknown function (DUF5009) - - - 0.000000000000000000000000000000000000000000000001094 190.0
HKD2_k127_5814041_9 - - - - 0.00000000000000000000013 102.0
HKD2_k127_5855541_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 3.742e-197 631.0
HKD2_k127_5855541_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 632.0
HKD2_k127_5855541_10 Participates in transcription elongation, termination and antitermination - - - 0.00000000000000000000000000000000000000000016 173.0
HKD2_k127_5855541_11 Transcriptional regulator K07729 - - 0.0000000000000000000007985 107.0
HKD2_k127_5855541_12 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 0.000000000000000004143 85.0
HKD2_k127_5855541_2 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 567.0
HKD2_k127_5855541_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008772 524.0
HKD2_k127_5855541_4 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 500.0
HKD2_k127_5855541_5 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 382.0
HKD2_k127_5855541_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 361.0
HKD2_k127_5855541_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003115 272.0
HKD2_k127_5855541_8 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000001545 215.0
HKD2_k127_5855541_9 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000001261 182.0
HKD2_k127_5892081_0 SAF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 582.0
HKD2_k127_5892081_1 Belongs to the DegT DnrJ EryC1 family K19430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 506.0
HKD2_k127_5892081_10 polysaccharide biosynthetic process K19431 - - 0.00000000000000000000000000006921 134.0
HKD2_k127_5892081_11 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000002887 123.0
HKD2_k127_5892081_12 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000009024 123.0
HKD2_k127_5892081_13 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 0.000000000000000003921 100.0
HKD2_k127_5892081_14 Glycosyl transferases group 1 - - - 0.0000000000000001627 95.0
HKD2_k127_5892081_15 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000001916 72.0
HKD2_k127_5892081_16 protein contain chitin-binding domain type 3 K01183,K21606 - 3.2.1.14,3.2.1.202 0.000000000822 73.0
HKD2_k127_5892081_17 Belongs to the glycosyl hydrolase 28 family - - - 0.0000007978 63.0
HKD2_k127_5892081_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 456.0
HKD2_k127_5892081_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 417.0
HKD2_k127_5892081_4 Capsular exopolysaccharide family K16554,K16692 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 329.0
HKD2_k127_5892081_5 Cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 325.0
HKD2_k127_5892081_6 Bacterial sugar transferase K19428 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007572 269.0
HKD2_k127_5892081_7 NUDIX domain K03207 - - 0.000000000000000000000000000000000000000000000000000000000000006196 221.0
HKD2_k127_5892081_8 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000007134 158.0
HKD2_k127_5892081_9 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000001919 142.0
HKD2_k127_5908338_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1057.0
HKD2_k127_5908338_1 peptidyl-tyrosine sulfation - - - 1.555e-231 739.0
HKD2_k127_5908338_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001203 232.0
HKD2_k127_5908338_11 PFAM EAL domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003538 236.0
HKD2_k127_5908338_12 YwiC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000804 210.0
HKD2_k127_5908338_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000008571 139.0
HKD2_k127_5908338_14 - - - - 0.00000000000000000000000000003905 126.0
HKD2_k127_5908338_15 Histidine kinase - - - 0.0000000000000000000000000002045 119.0
HKD2_k127_5908338_17 - - - - 0.0000000000001485 76.0
HKD2_k127_5908338_18 Nacht domain - - - 0.000000001114 71.0
HKD2_k127_5908338_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 566.0
HKD2_k127_5908338_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 542.0
HKD2_k127_5908338_4 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 424.0
HKD2_k127_5908338_5 molybdopterin oxidoreductase Fe4S4 region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 382.0
HKD2_k127_5908338_6 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 353.0
HKD2_k127_5908338_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 334.0
HKD2_k127_5908338_8 Aldehyde dehydrogenase K00131 - 1.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 311.0
HKD2_k127_5908338_9 amine dehydrogenase activity K14647,K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001494 303.0
HKD2_k127_593130_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 572.0
HKD2_k127_593130_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 399.0
HKD2_k127_593130_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 317.0
HKD2_k127_593130_3 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003945 260.0
HKD2_k127_593130_4 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.0000000000000000000000000000000000000000000000000000007824 213.0
HKD2_k127_593130_5 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000003305 184.0
HKD2_k127_593130_6 von Willebrand factor, type A K07114 - - 0.0000000000000000000000002271 123.0
HKD2_k127_593130_7 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0003092 53.0
HKD2_k127_594790_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.047e-219 696.0
HKD2_k127_594790_1 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007748 265.0
HKD2_k127_594790_2 O-acyltransferase activity K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000000000003447 240.0
HKD2_k127_594790_3 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000004277 231.0
HKD2_k127_594790_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000003224 138.0
HKD2_k127_594790_5 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000001512 66.0
HKD2_k127_6018294_0 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 318.0
HKD2_k127_6018294_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 297.0
HKD2_k127_6018294_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000001341 185.0
HKD2_k127_6018294_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000006794 164.0
HKD2_k127_6018294_4 Belongs to the ompA family K03640 - - 0.00000108 58.0
HKD2_k127_6018294_5 PFAM aldo keto reductase - - - 0.000008484 57.0
HKD2_k127_6048445_0 ATP:ADP antiporter activity K03301 - - 6.871e-195 630.0
HKD2_k127_6048445_1 cyclic nucleotide binding K00384,K10914,K16922 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000003787 203.0
HKD2_k127_6048445_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000009977 130.0
HKD2_k127_6048445_3 YtxH-like protein - - - 0.00000000002863 68.0
HKD2_k127_6051676_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 434.0
HKD2_k127_6051676_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 427.0
HKD2_k127_6051676_2 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001116 284.0
HKD2_k127_6051676_3 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000001361 260.0
HKD2_k127_6051676_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000001793 224.0
HKD2_k127_6051676_5 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000006919 220.0
HKD2_k127_6051676_6 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000000000000000000000000000000000001809 205.0
HKD2_k127_6051676_7 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000002594 164.0
HKD2_k127_6090545_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.219e-263 835.0
HKD2_k127_6090545_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 300.0
HKD2_k127_6090545_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001176 241.0
HKD2_k127_6090545_3 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000002006 170.0
HKD2_k127_6090545_4 AntiSigma factor - - - 0.000000000000000000000000005399 125.0
HKD2_k127_6090545_5 Glycosyl transferase family 41 - - - 0.0001574 51.0
HKD2_k127_6152988_0 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 554.0
HKD2_k127_6152988_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 442.0
HKD2_k127_6152988_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 424.0
HKD2_k127_6152988_3 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 388.0
HKD2_k127_6152988_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
HKD2_k127_6152988_5 PFAM glycoside hydrolase, family 9 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000001026 231.0
HKD2_k127_6152988_6 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.0000000000000000000000000000000003137 145.0
HKD2_k127_6152988_7 radical SAM domain protein K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000002947 84.0
HKD2_k127_6152988_8 base-excision repair, DNA ligation K10776,K10798 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0003950,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016886,GO:0019538,GO:0033554,GO:0034641,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0070212,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901564 2.4.2.30,6.5.1.1 0.00000001451 63.0
HKD2_k127_6172256_0 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 3.509e-246 788.0
HKD2_k127_6172256_1 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 616.0
HKD2_k127_6172256_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000002605 190.0
HKD2_k127_6172256_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000001412 195.0
HKD2_k127_6172256_12 Phospholipid methyltransferase - - - 0.0000000000000000000000006447 116.0
HKD2_k127_6172256_13 - - - - 0.0001564 51.0
HKD2_k127_6172256_2 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 443.0
HKD2_k127_6172256_3 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 447.0
HKD2_k127_6172256_4 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 416.0
HKD2_k127_6172256_5 Bacterial regulatory protein, Fis family K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 305.0
HKD2_k127_6172256_6 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 266.0
HKD2_k127_6172256_7 - - - - 0.000000000000000000000000000000000000000000000000000000001733 219.0
HKD2_k127_6172256_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000001106 216.0
HKD2_k127_6172256_9 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000889 193.0
HKD2_k127_6329021_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 553.0
HKD2_k127_6329021_1 Protein of unknown function (DUF2911) - - - 0.00000000000002272 87.0
HKD2_k127_6329021_2 - - - - 0.00000000000006769 73.0
HKD2_k127_6329021_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00004961 52.0
HKD2_k127_6382235_0 Fibronectin type III-like domain K05349 - 3.2.1.21 2.486e-281 883.0
HKD2_k127_6382235_1 PFAM Aldehyde dehydrogenase K13877 - 1.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 553.0
HKD2_k127_6382235_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 500.0
HKD2_k127_6382235_3 Belongs to the proline racemase family K12658 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855,GO:0036361,GO:0047580,GO:0047661 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 366.0
HKD2_k127_6382235_4 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 357.0
HKD2_k127_6382235_5 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 362.0
HKD2_k127_6382235_6 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001151 251.0
HKD2_k127_6382235_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714,K21062 - 3.5.4.22,4.3.3.7 0.00000000000000000000000000000000004961 147.0
HKD2_k127_6382235_8 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.000000000000000002973 92.0
HKD2_k127_6382235_9 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0000000003301 65.0
HKD2_k127_6438652_0 Hypothetical glycosyl hydrolase 6 - - - 1.628e-243 791.0
HKD2_k127_6438652_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 471.0
HKD2_k127_6438652_2 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 443.0
HKD2_k127_6438652_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 347.0
HKD2_k127_6438652_4 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000001048 197.0
HKD2_k127_6438652_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000000001052 180.0
HKD2_k127_6438652_6 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000000000007328 153.0
HKD2_k127_6438652_7 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000002999 161.0
HKD2_k127_6438652_8 Phosphotransferase enzyme family K12132 - 2.7.11.1 0.0000000000002225 74.0
HKD2_k127_6438652_9 PilZ domain - - - 0.00002086 53.0
HKD2_k127_6523980_0 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000278 231.0
HKD2_k127_6523980_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001384 220.0
HKD2_k127_6523980_2 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000005251 198.0
HKD2_k127_6523980_3 - - - - 0.000004104 59.0
HKD2_k127_6527975_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 612.0
HKD2_k127_6527975_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 582.0
HKD2_k127_6527975_10 Heat shock protein DnaJ domain protein - - - 0.00000000000001927 85.0
HKD2_k127_6527975_11 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03591 - - 0.00062 50.0
HKD2_k127_6527975_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 478.0
HKD2_k127_6527975_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 398.0
HKD2_k127_6527975_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 350.0
HKD2_k127_6527975_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 328.0
HKD2_k127_6527975_6 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 294.0
HKD2_k127_6527975_7 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
HKD2_k127_6527975_8 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000009525 213.0
HKD2_k127_6527975_9 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000001002 117.0
HKD2_k127_6553675_0 transcription factor binding K02584 - - 1.026e-207 657.0
HKD2_k127_6553675_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000001215 249.0
HKD2_k127_6553675_2 ggdef domain - - - 0.000000000000000000000000000000000000000000000000001026 205.0
HKD2_k127_6553675_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000004502 121.0
HKD2_k127_6553675_4 - - - - 0.00000000000000008816 91.0
HKD2_k127_6553675_5 PFAM Membrane protein of K08972 - - 0.0000000000000001265 91.0
HKD2_k127_6553675_6 GDSL-like Lipase/Acylhydrolase - - - 0.000000000002741 79.0
HKD2_k127_6605690_0 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 1.037e-316 985.0
HKD2_k127_6605690_1 Maltogenic Amylase, C-terminal domain K05343 - 3.2.1.1,5.4.99.16 1.529e-240 827.0
HKD2_k127_6605690_10 Glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000228 254.0
HKD2_k127_6605690_11 NIPSNAP family containing protein - - - 0.000000000000000000000000000000000000000000000000000000000008248 225.0
HKD2_k127_6605690_12 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000228 230.0
HKD2_k127_6605690_13 and related - - - 0.000000000000000000000000000000000000000000000000000000003228 222.0
HKD2_k127_6605690_14 Trehalose-phosphatase K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000005949 214.0
HKD2_k127_6605690_15 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000323 184.0
HKD2_k127_6605690_16 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000006658 163.0
HKD2_k127_6605690_17 Cupin domain - - - 0.000000000000000000000000000000000000001338 154.0
HKD2_k127_6605690_18 PHP domain protein - - - 0.00000000000000000000000000000000000003787 165.0
HKD2_k127_6605690_19 negative regulation of transcription, DNA-templated K10947 - - 0.000000000000000000000000000000000003818 143.0
HKD2_k127_6605690_2 carboxylic acid catabolic process K18334 - 4.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 610.0
HKD2_k127_6605690_20 DoxX K16937 - 1.8.5.2 0.00000000000000000000000002217 115.0
HKD2_k127_6605690_22 membrane - - - 0.00000000000000000001377 101.0
HKD2_k127_6605690_23 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000002197 85.0
HKD2_k127_6605690_24 GDSL-like Lipase/Acylhydrolase - - - 0.00000000009476 73.0
HKD2_k127_6605690_25 PFAM Conserved TM helix - - - 0.0003445 51.0
HKD2_k127_6605690_26 metallopeptidase activity K06889 - - 0.0006453 53.0
HKD2_k127_6605690_3 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 598.0
HKD2_k127_6605690_4 chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 453.0
HKD2_k127_6605690_5 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 394.0
HKD2_k127_6605690_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 374.0
HKD2_k127_6605690_7 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 329.0
HKD2_k127_6605690_8 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007485 270.0
HKD2_k127_6605690_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004545 275.0
HKD2_k127_6611080_0 Sortilin, neurotensin receptor 3, - - - 0.0 1110.0
HKD2_k127_6611080_1 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 9.894e-266 834.0
HKD2_k127_6611080_10 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 337.0
HKD2_k127_6611080_11 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001587 222.0
HKD2_k127_6611080_12 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000005891 207.0
HKD2_k127_6611080_13 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000001437 181.0
HKD2_k127_6611080_14 - - - - 0.000000000000000003416 100.0
HKD2_k127_6611080_2 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 2.117e-217 681.0
HKD2_k127_6611080_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 589.0
HKD2_k127_6611080_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 585.0
HKD2_k127_6611080_5 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 558.0
HKD2_k127_6611080_6 histidine kinase HAMP region domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 570.0
HKD2_k127_6611080_7 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 355.0
HKD2_k127_6611080_8 Transcriptional regulatory protein, C terminal K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 321.0
HKD2_k127_6611080_9 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 337.0
HKD2_k127_6626943_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 9.046e-254 807.0
HKD2_k127_6626943_1 Helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000003669 175.0
HKD2_k127_6626943_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000005529 114.0
HKD2_k127_6638138_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 346.0
HKD2_k127_6638138_1 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
HKD2_k127_6689616_0 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 612.0
HKD2_k127_6689616_1 Pirin C-terminal cupin domain K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 537.0
HKD2_k127_6689616_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 512.0
HKD2_k127_6689780_0 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 3.216e-295 930.0
HKD2_k127_6689780_1 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 431.0
HKD2_k127_6689780_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003507 271.0
HKD2_k127_6689780_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000009904 264.0
HKD2_k127_6689780_4 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000001695 255.0
HKD2_k127_6689780_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000001018 236.0
HKD2_k127_6689780_6 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000004468 128.0
HKD2_k127_6689780_7 response regulator receiver K07713,K07715 - - 0.0000000000004097 76.0
HKD2_k127_6767455_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003038 274.0
HKD2_k127_6767455_1 Diaminopimelate epimerase K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000006285 221.0
HKD2_k127_6767455_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000003249 181.0
HKD2_k127_6767455_3 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000002091 175.0
HKD2_k127_6767455_4 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000002419 138.0
HKD2_k127_6767455_5 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000003886 114.0
HKD2_k127_6767455_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000003014 99.0
HKD2_k127_6824810_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.432e-256 814.0
HKD2_k127_6824810_1 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 578.0
HKD2_k127_6824810_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 376.0
HKD2_k127_6824810_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000002896 156.0
HKD2_k127_6847333_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1086.0
HKD2_k127_6847333_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000428 133.0
HKD2_k127_6894211_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 2.876e-198 625.0
HKD2_k127_6894211_1 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002868 288.0
HKD2_k127_6894211_2 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000006092 153.0
HKD2_k127_6934478_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 346.0
HKD2_k127_6934478_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002668 263.0
HKD2_k127_6934478_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000003167 139.0
HKD2_k127_6934478_3 - - - - 0.0000000000002179 78.0
HKD2_k127_6952903_0 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 440.0
HKD2_k127_6952903_1 IPT/TIG domain - - - 0.000000001723 71.0
HKD2_k127_6972405_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0 1143.0
HKD2_k127_6972405_1 peptidase S9 - - - 1.685e-219 709.0
HKD2_k127_6972405_2 short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 574.0
HKD2_k127_6972405_3 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 352.0
HKD2_k127_6972405_4 PFAM Oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 315.0
HKD2_k127_6972405_5 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000008603 266.0
HKD2_k127_6972405_6 Methyltransferase - - - 0.000000000000000000000000000000000000000001046 166.0
HKD2_k127_6972405_7 - - - - 0.0000000000000000000000000000000002886 143.0
HKD2_k127_6972405_8 - - - - 0.00000000000000001622 93.0
HKD2_k127_6972405_9 Polymer-forming cytoskeletal - - - 0.0000000001593 71.0
HKD2_k127_697929_0 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 545.0
HKD2_k127_697929_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 396.0
HKD2_k127_697929_11 PEGA domain - - - 0.0001838 52.0
HKD2_k127_697929_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 315.0
HKD2_k127_697929_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 261.0
HKD2_k127_697929_4 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005439 224.0
HKD2_k127_697929_5 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000008357 137.0
HKD2_k127_697929_6 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000021 124.0
HKD2_k127_697929_7 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000002566 109.0
HKD2_k127_697929_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000003601 116.0
HKD2_k127_697929_9 Involved in the tonB-independent uptake of proteins - - - 0.0000002746 53.0
HKD2_k127_6987115_0 Peptidase family M28 - - - 4.081e-295 959.0
HKD2_k127_6987115_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.044e-219 688.0
HKD2_k127_6987115_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000001138 97.0
HKD2_k127_6987115_12 protein folding - - - 0.000000006181 68.0
HKD2_k127_6987115_14 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001235 65.0
HKD2_k127_6987115_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 541.0
HKD2_k127_6987115_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 445.0
HKD2_k127_6987115_4 Aldose 1-epimerase K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002798 285.0
HKD2_k127_6987115_5 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000613 274.0
HKD2_k127_6987115_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000002578 210.0
HKD2_k127_6987115_7 capsule polysaccharide biosynthetic process - - - 0.000000000000000000000000000000002235 149.0
HKD2_k127_6987115_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000001532 139.0
HKD2_k127_6987115_9 oxidoreductase activity - - - 0.000000000000000000000001078 121.0
HKD2_k127_7012441_0 Protein of unknown function (DUF4038) - - - 5.022e-309 957.0
HKD2_k127_7012441_1 PFAM oxidoreductase domain protein - - - 3.016e-220 694.0
HKD2_k127_7012441_2 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 506.0
HKD2_k127_7012441_3 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 330.0
HKD2_k127_7012441_4 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 311.0
HKD2_k127_7012441_5 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002037 268.0
HKD2_k127_7058841_0 malic protein domain protein K00027 - 1.1.1.38 1.198e-248 780.0
HKD2_k127_7058841_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.626e-222 704.0
HKD2_k127_7058841_10 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K19517 - 2.7.1.15,2.7.1.64 0.0000000000000000000000000000000000000000003971 168.0
HKD2_k127_7058841_12 Diguanylate cyclase K21084 - 2.7.7.65 0.0000000000000000000000000000000000000000223 174.0
HKD2_k127_7058841_13 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000002639 158.0
HKD2_k127_7058841_14 ABC transporter K02003 - - 0.000000000000000000000000000000000004589 139.0
HKD2_k127_7058841_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000001069 138.0
HKD2_k127_7058841_16 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000001207 135.0
HKD2_k127_7058841_17 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000005121 123.0
HKD2_k127_7058841_18 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000006724 103.0
HKD2_k127_7058841_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 621.0
HKD2_k127_7058841_20 polysaccharide catabolic process - - - 0.0000000000003936 82.0
HKD2_k127_7058841_21 - - - - 0.00000000001117 77.0
HKD2_k127_7058841_22 Protein of unknown function (DUF3179) - - - 0.000000004107 57.0
HKD2_k127_7058841_3 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 577.0
HKD2_k127_7058841_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 515.0
HKD2_k127_7058841_5 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 416.0
HKD2_k127_7058841_6 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 408.0
HKD2_k127_7058841_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000005557 243.0
HKD2_k127_7058841_8 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000001285 213.0
HKD2_k127_7058841_9 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000001365 199.0
HKD2_k127_7222669_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 511.0
HKD2_k127_7222669_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 484.0
HKD2_k127_7222669_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 347.0
HKD2_k127_7222669_3 - - - - 0.00000000000000003305 96.0
HKD2_k127_7222669_4 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K09774 - - 0.00000000002873 77.0
HKD2_k127_72677_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1489.0
HKD2_k127_72677_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 9.78e-218 683.0
HKD2_k127_72677_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 386.0
HKD2_k127_72677_11 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 380.0
HKD2_k127_72677_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 366.0
HKD2_k127_72677_13 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 359.0
HKD2_k127_72677_14 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008884 356.0
HKD2_k127_72677_15 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000009153 242.0
HKD2_k127_72677_16 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000002473 221.0
HKD2_k127_72677_17 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000004605 216.0
HKD2_k127_72677_18 - - - - 0.00000000000000000000000000000000000000000000000000007358 207.0
HKD2_k127_72677_19 - K07018 - - 0.0000000000000000000000000000000000000000000000000001591 192.0
HKD2_k127_72677_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 624.0
HKD2_k127_72677_20 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000025 172.0
HKD2_k127_72677_21 metallopeptidase activity K06974 - - 0.00000000000000000000000000001454 137.0
HKD2_k127_72677_22 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000622 130.0
HKD2_k127_72677_23 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000006788 65.0
HKD2_k127_72677_24 helix_turn _helix lactose operon repressor K02529 - - 0.000000937 60.0
HKD2_k127_72677_3 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 580.0
HKD2_k127_72677_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 535.0
HKD2_k127_72677_5 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 509.0
HKD2_k127_72677_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 456.0
HKD2_k127_72677_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 437.0
HKD2_k127_72677_8 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 424.0
HKD2_k127_72677_9 PFAM Alkyl hydroperoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 435.0
HKD2_k127_7272840_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 8.376e-302 936.0
HKD2_k127_7272840_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 611.0
HKD2_k127_7272840_10 Bacterial membrane protein, YfhO - - - 0.0001117 54.0
HKD2_k127_7272840_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 451.0
HKD2_k127_7272840_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 418.0
HKD2_k127_7272840_4 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 393.0
HKD2_k127_7272840_5 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 339.0
HKD2_k127_7272840_6 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 334.0
HKD2_k127_7272840_7 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000003717 196.0
HKD2_k127_7272840_8 PFAM Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000001232 188.0
HKD2_k127_7272840_9 PFAM N-acetylneuraminic acid synthase K01654,K15898,K18430 - 2.5.1.101,2.5.1.56,2.5.1.97 0.000000000000000000000000002181 124.0
HKD2_k127_7275019_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.029e-201 644.0
HKD2_k127_7275019_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 565.0
HKD2_k127_7275019_10 Carboxypeptidase regulatory-like domain - - - 0.0006917 52.0
HKD2_k127_7275019_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 571.0
HKD2_k127_7275019_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 482.0
HKD2_k127_7275019_4 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 473.0
HKD2_k127_7275019_5 Phosphoesterase, PA-phosphatase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002634 271.0
HKD2_k127_7275019_6 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000002441 223.0
HKD2_k127_7275019_7 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000003543 142.0
HKD2_k127_7275019_8 - - - - 0.000000000594 66.0
HKD2_k127_7275019_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000001449 67.0
HKD2_k127_7425013_0 Serine carboxypeptidase - - - 6.902e-238 746.0
HKD2_k127_7425013_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 469.0
HKD2_k127_7425013_10 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000006077 226.0
HKD2_k127_7425013_11 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000001761 205.0
HKD2_k127_7425013_12 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000001696 194.0
HKD2_k127_7425013_13 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000001822 193.0
HKD2_k127_7425013_14 penicillin binding - - - 0.00000000000000000000000000000000000000002228 169.0
HKD2_k127_7425013_15 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000001831 162.0
HKD2_k127_7425013_16 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000119 146.0
HKD2_k127_7425013_17 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.00000000000000000000000000000001126 149.0
HKD2_k127_7425013_18 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000001137 120.0
HKD2_k127_7425013_19 response regulator receiver K07814 - - 0.00000000000000000000000001574 123.0
HKD2_k127_7425013_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 428.0
HKD2_k127_7425013_20 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.00000000000000000000004695 102.0
HKD2_k127_7425013_21 NUDIX domain - - - 0.0000000000000000000003295 102.0
HKD2_k127_7425013_22 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000005756 98.0
HKD2_k127_7425013_23 PFAM PEGA domain - - - 0.0000000000002281 81.0
HKD2_k127_7425013_24 Peptidase M56 - - - 0.000000000001412 80.0
HKD2_k127_7425013_25 - - - - 0.00005781 55.0
HKD2_k127_7425013_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 379.0
HKD2_k127_7425013_4 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 387.0
HKD2_k127_7425013_5 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 311.0
HKD2_k127_7425013_6 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 290.0
HKD2_k127_7425013_7 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001843 268.0
HKD2_k127_7425013_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000002769 253.0
HKD2_k127_7425013_9 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000002897 243.0
HKD2_k127_7518101_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 563.0
HKD2_k127_7518101_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000001024 170.0
HKD2_k127_7518101_2 GtrA-like protein - - - 0.00000000000000000000000000000000000000000035 177.0
HKD2_k127_7518101_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000001263 104.0
HKD2_k127_7523852_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 5.883e-217 700.0
HKD2_k127_7523852_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 553.0
HKD2_k127_7523852_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 348.0
HKD2_k127_7523852_3 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
HKD2_k127_7523852_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000761 283.0
HKD2_k127_7523852_5 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006831 269.0
HKD2_k127_7523852_6 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000007127 267.0
HKD2_k127_7523852_7 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.000000000000000000000000000000000219 138.0
HKD2_k127_7523852_8 - - - - 0.0000000000000000000000000001324 135.0
HKD2_k127_7532521_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 5.75e-210 664.0
HKD2_k127_7532521_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000146 208.0
HKD2_k127_7532521_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000004802 144.0
HKD2_k127_7532521_3 Domain of unknown function (DUF4912) K09942 - - 0.00000000000001295 85.0
HKD2_k127_7573685_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 481.0
HKD2_k127_7573685_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 370.0
HKD2_k127_7573685_2 PFAM Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 335.0
HKD2_k127_7573685_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 300.0
HKD2_k127_7573685_4 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000001098 259.0
HKD2_k127_7573685_5 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000009242 132.0
HKD2_k127_7573685_6 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000009476 119.0
HKD2_k127_7573685_7 cyclic nucleotide binding K04739,K10914 - - 0.00000000000000000002384 105.0
HKD2_k127_7573685_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000003508 81.0
HKD2_k127_7573685_9 heat shock protein binding - - - 0.00000000000009406 85.0
HKD2_k127_758293_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 484.0
HKD2_k127_758293_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 424.0
HKD2_k127_758293_2 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 383.0
HKD2_k127_758293_3 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000004729 238.0
HKD2_k127_758293_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000641 208.0
HKD2_k127_758293_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000003923 189.0
HKD2_k127_758293_6 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000000009545 166.0
HKD2_k127_758293_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000004525 83.0
HKD2_k127_7590897_0 PFAM MscS Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 432.0
HKD2_k127_7590897_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 342.0
HKD2_k127_7679871_0 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 289.0
HKD2_k127_7679871_1 SpoIVB peptidase S55 - - - 0.00000000000000000000000000000000000000000000000000000001288 208.0
HKD2_k127_7679871_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0040007,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000002991 97.0
HKD2_k127_7679871_4 Periplasmic component of the Tol biopolymer transport K03641 - - 0.0003463 53.0
HKD2_k127_7686069_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 4.323e-229 729.0
HKD2_k127_7686069_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000001339 226.0
HKD2_k127_7686069_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000001552 125.0
HKD2_k127_7686069_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000005454 113.0
HKD2_k127_7686069_4 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000007797 92.0
HKD2_k127_7686069_5 - - - - 0.000001755 61.0
HKD2_k127_768873_0 Tricorn protease homolog - - - 0.0 1380.0
HKD2_k127_768873_1 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 3.186e-250 794.0
HKD2_k127_768873_10 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 339.0
HKD2_k127_768873_11 Glycosyl hydrolases family 28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 303.0
HKD2_k127_768873_12 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001003 257.0
HKD2_k127_768873_13 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000001896 239.0
HKD2_k127_768873_14 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000003754 252.0
HKD2_k127_768873_15 PAS domain containing protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000006476 233.0
HKD2_k127_768873_16 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000003208 200.0
HKD2_k127_768873_17 Tannase and feruloyl esterase - - - 0.00000000000000000000000000000000000000001158 160.0
HKD2_k127_768873_18 Acid phosphatase homologues - - - 0.00000000000000002992 95.0
HKD2_k127_768873_19 Aldo/keto reductase family - - - 0.0000000004006 72.0
HKD2_k127_768873_2 Peptidase family M49 - - - 3.691e-228 723.0
HKD2_k127_768873_20 Thiol-disulfide isomerase and thioredoxins - - - 0.00002955 56.0
HKD2_k127_768873_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.526e-195 625.0
HKD2_k127_768873_4 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 548.0
HKD2_k127_768873_5 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 484.0
HKD2_k127_768873_6 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 470.0
HKD2_k127_768873_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 444.0
HKD2_k127_768873_8 Putative esterase K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 441.0
HKD2_k127_768873_9 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 363.0
HKD2_k127_7696458_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 584.0
HKD2_k127_7696458_1 PFAM Carbamoyl-phosphate synthase L chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 520.0
HKD2_k127_7696458_10 transferase activity, transferring glycosyl groups - - - 0.00000000000000000001051 100.0
HKD2_k127_7696458_11 PFAM Forkhead-associated protein - - - 0.0000000000000008669 89.0
HKD2_k127_7696458_12 FeoA K04758 - - 0.0000000001601 67.0
HKD2_k127_7696458_13 RDD family - - - 0.000000319 62.0
HKD2_k127_7696458_2 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 484.0
HKD2_k127_7696458_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 457.0
HKD2_k127_7696458_4 Glycosyl transferases group 1 K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 397.0
HKD2_k127_7696458_5 Bacillithiol biosynthesis BshC K22136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003541 267.0
HKD2_k127_7696458_6 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000009519 263.0
HKD2_k127_7696458_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000003382 192.0
HKD2_k127_7696458_8 GlcNAc-PI de-N-acetylase K01463 - - 0.0000000000000000000000000000000000000000000004574 187.0
HKD2_k127_7696458_9 - - - - 0.000000000000000000004582 96.0
HKD2_k127_7763776_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 545.0
HKD2_k127_7763776_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 509.0
HKD2_k127_7763776_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 466.0
HKD2_k127_7763776_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 343.0
HKD2_k127_7763776_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 322.0
HKD2_k127_7763776_5 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000006391 145.0
HKD2_k127_7763776_6 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000001186 157.0
HKD2_k127_7763776_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000001453 123.0
HKD2_k127_7763776_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000001643 109.0
HKD2_k127_7763776_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000001564 113.0
HKD2_k127_7772895_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 337.0
HKD2_k127_7772895_1 phosphorelay signal transduction system K01768,K10941,K11894 - 4.6.1.1 0.0000000000004212 74.0
HKD2_k127_7784594_0 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 601.0
HKD2_k127_7784594_1 amidohydrolase K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 602.0
HKD2_k127_7784594_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000001623 268.0
HKD2_k127_7784594_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000001091 263.0
HKD2_k127_7784594_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000349 248.0
HKD2_k127_7784594_5 PFAM Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000547 185.0
HKD2_k127_7784594_6 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000004156 118.0
HKD2_k127_7784594_7 DoxX K16937 - 1.8.5.2 0.000000000000000000001691 109.0
HKD2_k127_7784594_8 serine threonine protein kinase - - - 0.00000000000000000002266 107.0
HKD2_k127_7784594_9 Glycosyl hydrolase-like 10 - - - 0.0000000000005191 83.0
HKD2_k127_7845423_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 325.0
HKD2_k127_7845423_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009668 273.0
HKD2_k127_7845423_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001396 278.0
HKD2_k127_7845423_3 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033817,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000002401 238.0
HKD2_k127_7845423_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000002793 119.0
HKD2_k127_7929252_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 463.0
HKD2_k127_7929252_1 Amp-dependent synthetase and ligase K00797,K01897 - 2.5.1.16,6.2.1.3 0.0000000000000000000000000000000000000000000001599 193.0
HKD2_k127_7929252_2 Lipoprotein K05811 - - 0.00000000000000000000000000000000000002601 163.0
HKD2_k127_7929252_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00334,K00335 - 1.6.5.3 0.0000000000000000000000000000000000002672 147.0
HKD2_k127_7929252_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000006515 143.0
HKD2_k127_7929252_5 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000042 135.0
HKD2_k127_7929252_6 PDZ DHR GLGF domain protein - - - 0.00000000000000000000004676 114.0
HKD2_k127_7929252_7 protein involved in cysteine biosynthesis K06203 - - 0.00000000000000000002014 101.0
HKD2_k127_7929252_8 - - - - 0.0000000000000001775 94.0
HKD2_k127_7929252_9 - - - - 0.0000006494 56.0
HKD2_k127_8054882_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 563.0
HKD2_k127_8054882_1 L-lactate permease K03303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 515.0
HKD2_k127_8054882_2 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 453.0
HKD2_k127_8054882_3 COGs COG0673 dehydrogenase and related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 432.0
HKD2_k127_8054882_4 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 332.0
HKD2_k127_8054882_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 309.0
HKD2_k127_8054882_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000004898 103.0
HKD2_k127_8054882_7 protein conserved in bacteria K09955 - - 0.0000000000000003614 93.0
HKD2_k127_8054882_9 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00002662 48.0
HKD2_k127_8074137_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.52e-250 787.0
HKD2_k127_8074137_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 564.0
HKD2_k127_8074137_2 Biotin carboxylase K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 551.0
HKD2_k127_8074137_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
HKD2_k127_8074137_4 Proteasome subunit K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000004154 223.0
HKD2_k127_8074137_5 Biotin-requiring enzyme - - - 0.00000000000000000000001622 106.0
HKD2_k127_8074137_6 Fibronectin type 3 domain - - - 0.000000000000002768 89.0
HKD2_k127_8074137_7 Putative regulatory protein - - - 0.0000426 55.0
HKD2_k127_8107639_0 cellulose binding - - - 0.0 1233.0
HKD2_k127_8107639_1 Aminotransferase K14267,K14287 - 2.6.1.17,2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 478.0
HKD2_k127_8107639_2 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 449.0
HKD2_k127_8107639_3 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 301.0
HKD2_k127_8107639_4 Endonuclease exonuclease phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 302.0
HKD2_k127_8107639_5 efflux transmembrane transporter activity K15725 - - 0.00000000000000000000000000000000000000000000000001038 197.0
HKD2_k127_8107639_6 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000007278 119.0
HKD2_k127_8150057_0 Belongs to the PEP-utilizing enzyme family K01006,K22424 - 2.7.3.13,2.7.9.1 4.671e-236 745.0
HKD2_k127_8150057_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 369.0
HKD2_k127_8150057_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 377.0
HKD2_k127_8150057_3 DoxX - - - 0.0000000000000003703 89.0
HKD2_k127_8150057_4 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000004545 90.0
HKD2_k127_8150057_5 Rhodanese Homology Domain - - - 0.00000000005572 69.0
HKD2_k127_8160710_0 Proton-conducting membrane transporter K12137,K15828 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 413.0
HKD2_k127_8160710_1 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.0001465 50.0
HKD2_k127_8180037_0 beta-galactosidase activity K05989 - 3.2.1.40 0.0 1068.0
HKD2_k127_8180037_1 PFAM Major Facilitator Superfamily K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 549.0
HKD2_k127_8180037_2 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 398.0
HKD2_k127_8180037_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 392.0
HKD2_k127_8180037_4 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 294.0
HKD2_k127_8180037_5 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.0000000000000000000000000000000000000001709 156.0
HKD2_k127_8223039_0 Sigma-54 interaction domain K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 405.0
HKD2_k127_8223039_1 MarR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000002103 181.0
HKD2_k127_8223039_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000003275 146.0
HKD2_k127_8223039_3 Histidine kinase K13598 - 2.7.13.3 0.0000000000000000000000000000002326 143.0
HKD2_k127_8223039_4 DinB family - - - 0.00000000000000000000000000003229 123.0
HKD2_k127_8223039_5 - - - - 0.00000000000000000000000000006936 123.0
HKD2_k127_8223039_6 Transglycosylase associated protein - - - 0.00000000000000000000000000008688 116.0
HKD2_k127_8223039_7 - - - - 0.000000000003718 72.0
HKD2_k127_8224478_0 Type II/IV secretion system protein K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 461.0
HKD2_k127_8224478_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 456.0
HKD2_k127_8224478_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 308.0
HKD2_k127_8224478_3 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008218 276.0
HKD2_k127_8224478_4 Glycosyl hydrolase-like 10 - - - 0.0000001472 59.0
HKD2_k127_825778_0 major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004878 271.0
HKD2_k127_825778_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000009663 137.0
HKD2_k127_825778_5 Sulfatase-modifying factor enzyme 1 - - - 0.0000000002813 72.0
HKD2_k127_825778_6 transcriptional regulator domain protein - - - 0.000000006124 70.0
HKD2_k127_8304657_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 464.0
HKD2_k127_8304657_1 NAD binding K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 421.0
HKD2_k127_8304657_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000001321 113.0
HKD2_k127_8304657_11 zinc metalloprotease K11749 - - 0.00000655 59.0
HKD2_k127_8304657_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 402.0
HKD2_k127_8304657_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 341.0
HKD2_k127_8304657_4 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 261.0
HKD2_k127_8304657_5 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000001378 243.0
HKD2_k127_8304657_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000009775 239.0
HKD2_k127_8304657_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000001053 172.0
HKD2_k127_8304657_8 - - - - 0.00000000000000000000000000000000000000001198 160.0
HKD2_k127_8304657_9 PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000001638 142.0
HKD2_k127_8350825_0 Peptidase inhibitor I9 K20754 - 3.4.21.111 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 344.0
HKD2_k127_8350825_1 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 318.0
HKD2_k127_8350825_2 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000001708 274.0
HKD2_k127_8350825_3 DinB family - - - 0.000000000000000000000000000000000000001208 153.0
HKD2_k127_8350825_4 DinB superfamily - - - 0.0000000000000000000000000000000004636 138.0
HKD2_k127_8350825_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000005757 135.0
HKD2_k127_8350825_6 COG0076 Glutamate decarboxylase and related PLP-dependent proteins - - - 0.00000000000000000000000000001066 122.0
HKD2_k127_8350825_7 peptidyl-tyrosine sulfation - - - 0.0000000000000000004308 96.0
HKD2_k127_8350825_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000001202 65.0
HKD2_k127_8359880_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 464.0
HKD2_k127_8359880_1 FHA domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000001289 177.0
HKD2_k127_8359880_2 receptor - - - 0.00000000000000000000001811 116.0
HKD2_k127_842131_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 503.0
HKD2_k127_842131_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 380.0
HKD2_k127_842131_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000005264 226.0
HKD2_k127_842131_3 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000002534 186.0
HKD2_k127_842131_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000006805 178.0
HKD2_k127_842131_5 Peptidase family M54 K06974 - - 0.00000000000000000000000005336 115.0
HKD2_k127_842131_6 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000002851 108.0
HKD2_k127_842131_7 General secretion pathway protein C K02452 - - 0.0000004783 60.0
HKD2_k127_842131_8 diguanylate cyclase - - - 0.00000074 61.0
HKD2_k127_842131_9 - - - - 0.000001155 57.0
HKD2_k127_8422329_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 445.0
HKD2_k127_8422329_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 411.0
HKD2_k127_8422329_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 327.0
HKD2_k127_8422329_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007282 295.0
HKD2_k127_8422329_4 ABC transporter K06861 - - 0.000000000000000000000000001068 113.0
HKD2_k127_8422329_5 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000002152 110.0
HKD2_k127_8422329_6 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0000000000000000000001358 98.0
HKD2_k127_8422329_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000005579 109.0
HKD2_k127_8422329_8 Phosphotransferase System K11189 - - 0.0000000000000000006827 94.0
HKD2_k127_8585266_0 PFAM Glycoside hydrolase, family 20 K12373 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 625.0
HKD2_k127_8585266_1 beta-galactosidase activity K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 591.0
HKD2_k127_8585266_10 - - - - 0.00000000262 68.0
HKD2_k127_8585266_11 Tetratricopeptide repeat K02200 - - 0.0001034 53.0
HKD2_k127_8585266_2 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 571.0
HKD2_k127_8585266_3 Major facilitator Superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 501.0
HKD2_k127_8585266_4 SMART serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 492.0
HKD2_k127_8585266_5 COGs COG0515 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 359.0
HKD2_k127_8585266_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 334.0
HKD2_k127_8585266_7 Belongs to the glycosyl hydrolase 2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 316.0
HKD2_k127_8585266_8 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000007299 116.0
HKD2_k127_8585266_9 - - - - 0.0000000005472 72.0
HKD2_k127_8625301_0 PFAM Phosphoribosyltransferase K02242 - - 0.000000000000000000000000000000007595 138.0
HKD2_k127_8625301_1 S1 P1 Nuclease - - - 0.0000000000000000000000000003731 124.0
HKD2_k127_8625301_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000004131 121.0
HKD2_k127_8625301_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000004063 91.0
HKD2_k127_864201_0 LytB protein K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 446.0
HKD2_k127_864201_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 348.0
HKD2_k127_864201_10 phytol kinase 2, chloroplastic K15892 GO:0000003,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0006066,GO:0006629,GO:0006714,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0007275,GO:0008150,GO:0008152,GO:0009719,GO:0009725,GO:0009737,GO:0009791,GO:0009908,GO:0009987,GO:0010033,GO:0016093,GO:0016301,GO:0016310,GO:0016487,GO:0016740,GO:0016772,GO:0016773,GO:0016999,GO:0017144,GO:0022414,GO:0032501,GO:0032502,GO:0033993,GO:0034308,GO:0042221,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0048367,GO:0048437,GO:0048438,GO:0048440,GO:0048467,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0052668,GO:0052669,GO:0052670,GO:0052671,GO:0052673,GO:0061458,GO:0071704,GO:0090567,GO:0097305,GO:0099402,GO:1901615,GO:1901700 2.7.1.216 0.0001006 56.0
HKD2_k127_864201_2 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0033554,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0055114,GO:0065003,GO:0070417,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
HKD2_k127_864201_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 315.0
HKD2_k127_864201_4 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000003917 296.0
HKD2_k127_864201_5 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000001462 235.0
HKD2_k127_864201_6 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.0000000000000000000000000000000000000000000000000000000002834 231.0
HKD2_k127_864201_7 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.0000000000000000000000000000000301 146.0
HKD2_k127_864201_8 COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000009331 141.0
HKD2_k127_864201_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000001836 91.0
HKD2_k127_8643115_0 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 551.0
HKD2_k127_8643115_1 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 457.0
HKD2_k127_8643115_10 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000004603 155.0
HKD2_k127_8643115_11 - - - - 0.000000000000000000000000000000009695 143.0
HKD2_k127_8643115_13 Lipid A 3-O-deacylase (PagL) - - - 0.0000001464 61.0
HKD2_k127_8643115_15 - - - - 0.0002245 53.0
HKD2_k127_8643115_2 Aminotransferase class-V K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 447.0
HKD2_k127_8643115_3 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 377.0
HKD2_k127_8643115_4 Phosphomannose isomerase type I K01809,K01840 - 5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 356.0
HKD2_k127_8643115_5 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 306.0
HKD2_k127_8643115_6 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 286.0
HKD2_k127_8643115_7 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001063 263.0
HKD2_k127_8643115_8 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000003752 209.0
HKD2_k127_8643115_9 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000003981 213.0
HKD2_k127_8649657_0 Putative carbohydrate binding domain K00702 - 2.4.1.20 0.0 1204.0
HKD2_k127_8649657_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 1.576e-312 975.0
HKD2_k127_8649657_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 1.394e-217 695.0
HKD2_k127_8649657_3 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 7.34e-198 634.0
HKD2_k127_8649657_4 ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 572.0
HKD2_k127_8649657_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 427.0
HKD2_k127_8649657_6 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 327.0
HKD2_k127_8649657_7 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001321 289.0
HKD2_k127_8649657_8 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000001256 198.0
HKD2_k127_8721078_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 509.0
HKD2_k127_8721078_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 460.0
HKD2_k127_8721078_10 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000003518 207.0
HKD2_k127_8721078_11 dCMP deaminase activity K01493 - 3.5.4.12 0.000000000000000000000000000000000000000008159 158.0
HKD2_k127_8721078_12 belongs to the sigma-70 factor family, ECF subfamily K03088 GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000006269 158.0
HKD2_k127_8721078_13 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000000001204 157.0
HKD2_k127_8721078_14 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000006887 131.0
HKD2_k127_8721078_15 Putative zinc-finger - - - 0.0000008675 60.0
HKD2_k127_8721078_2 Sugar transport protein K05340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 410.0
HKD2_k127_8721078_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 406.0
HKD2_k127_8721078_4 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 399.0
HKD2_k127_8721078_5 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 360.0
HKD2_k127_8721078_6 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 346.0
HKD2_k127_8721078_7 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 323.0
HKD2_k127_8721078_8 periplasmic ligand-binding sensor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 313.0
HKD2_k127_8721078_9 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000009205 216.0
HKD2_k127_8737729_0 siderophore transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 554.0
HKD2_k127_8737729_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 504.0
HKD2_k127_8737729_10 transcriptional K02081 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 301.0
HKD2_k127_8737729_11 LysM domain - - - 0.000000000000000000000000000000000000000000000001976 183.0
HKD2_k127_8737729_12 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000006803 147.0
HKD2_k127_8737729_13 amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000001993 129.0
HKD2_k127_8737729_14 oxidoreductase activity - - - 0.0000000000000000000000001254 125.0
HKD2_k127_8737729_15 pfkB family carbohydrate kinase - - - 0.0000000000000000000000005464 120.0
HKD2_k127_8737729_2 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 476.0
HKD2_k127_8737729_3 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 435.0
HKD2_k127_8737729_4 Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 419.0
HKD2_k127_8737729_5 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 422.0
HKD2_k127_8737729_6 Tagatose 6 phosphate kinase K16371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 384.0
HKD2_k127_8737729_7 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 378.0
HKD2_k127_8737729_8 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 344.0
HKD2_k127_8737729_9 isomerase K02082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 346.0
HKD2_k127_8738807_0 enterobactin catabolic process - - - 1.544e-237 764.0
HKD2_k127_8738807_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 578.0
HKD2_k127_8738807_10 helix_turn_helix gluconate operon transcriptional repressor K07978 - - 0.0000000000000000000000002822 117.0
HKD2_k127_8738807_11 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000002164 95.0
HKD2_k127_8738807_12 PFAM cytochrome c class III - - - 0.00000000000000026 91.0
HKD2_k127_8738807_2 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 342.0
HKD2_k127_8738807_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 297.0
HKD2_k127_8738807_4 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004027 288.0
HKD2_k127_8738807_5 molybdopterin cofactor binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001254 270.0
HKD2_k127_8738807_6 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000000000000000000000000005912 196.0
HKD2_k127_8738807_7 Acyltransferase - - - 0.00000000000000000000000000000000000000000000286 188.0
HKD2_k127_8738807_8 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000007205 123.0
HKD2_k127_8738807_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000007315 136.0
HKD2_k127_8759491_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 537.0
HKD2_k127_8759491_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 503.0
HKD2_k127_8759491_10 Phosphate acyltransferases - - - 0.0000000000000000000000000000002267 140.0
HKD2_k127_8759491_11 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000002788 125.0
HKD2_k127_8759491_12 peptidyl-tyrosine sulfation - - - 0.00000000000000005841 93.0
HKD2_k127_8759491_13 Biopolymer transport protein K03559,K03560 - - 0.0000000000000008966 91.0
HKD2_k127_8759491_14 - - - - 0.0000000000006043 79.0
HKD2_k127_8759491_15 biopolymer transport protein ExbD K03559 - - 0.0000000000007804 73.0
HKD2_k127_8759491_16 Tetratricopeptide repeat - - - 0.0000000005279 73.0
HKD2_k127_8759491_17 - - - - 0.0000000005683 71.0
HKD2_k127_8759491_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 407.0
HKD2_k127_8759491_3 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 414.0
HKD2_k127_8759491_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 366.0
HKD2_k127_8759491_5 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002441 286.0
HKD2_k127_8759491_6 von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000004284 255.0
HKD2_k127_8759491_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001575 241.0
HKD2_k127_8759491_8 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003851 244.0
HKD2_k127_8759491_9 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000008973 185.0
HKD2_k127_8762378_0 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 303.0
HKD2_k127_8762378_1 cation proton antiporter K12141 - - 0.00000000000000000000000000000000000000000000000000000000009884 213.0
HKD2_k127_8762378_2 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000002689 152.0
HKD2_k127_8842271_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000004444 282.0
HKD2_k127_8842271_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000009126 161.0
HKD2_k127_8842271_2 Type II secretory pathway component ExeA K02450 - - 0.0000001308 60.0
HKD2_k127_8941261_0 Fibronectin type III-like domain K05349 - 3.2.1.21 3.033e-303 954.0
HKD2_k127_8941261_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 343.0
HKD2_k127_8941261_10 PFAM DivIVA family protein K04074 - - 0.000000000000000000006657 99.0
HKD2_k127_8941261_11 peptidyl-tyrosine sulfation - - - 0.000000000000000001205 97.0
HKD2_k127_8941261_12 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001633 85.0
HKD2_k127_8941261_13 DNA-binding transcription factor activity - - - 0.000000000000004533 79.0
HKD2_k127_8941261_14 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.0000000000002254 75.0
HKD2_k127_8941261_15 Putative zinc- or iron-chelating domain K18475 - - 0.00000000002264 78.0
HKD2_k127_8941261_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 312.0
HKD2_k127_8941261_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002495 274.0
HKD2_k127_8941261_4 glyoxalase III activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002102 258.0
HKD2_k127_8941261_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000008756 252.0
HKD2_k127_8941261_6 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001367 234.0
HKD2_k127_8941261_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000006515 213.0
HKD2_k127_8941261_8 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000004636 177.0
HKD2_k127_8941261_9 DUF167 K09131 - - 0.000000000000000000005643 96.0
HKD2_k127_8956907_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 2.386e-195 622.0
HKD2_k127_8956907_1 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 614.0
HKD2_k127_8956907_10 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000004046 214.0
HKD2_k127_8956907_11 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000004041 176.0
HKD2_k127_8956907_12 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000009296 125.0
HKD2_k127_8956907_13 Hydrogenase maturation protease - - - 0.000000000000000001758 100.0
HKD2_k127_8956907_14 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.0000000000001144 77.0
HKD2_k127_8956907_2 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 561.0
HKD2_k127_8956907_3 Acyl-CoA dehydrogenase, C-terminal domain K16173 - 1.3.99.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 538.0
HKD2_k127_8956907_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 481.0
HKD2_k127_8956907_5 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 403.0
HKD2_k127_8956907_6 2 iron, 2 sulfur cluster binding K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 364.0
HKD2_k127_8956907_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 358.0
HKD2_k127_8956907_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 341.0
HKD2_k127_8956907_9 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000007919 229.0
HKD2_k127_895785_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 511.0
HKD2_k127_895785_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006436 280.0
HKD2_k127_895785_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000277 260.0
HKD2_k127_895785_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000005005 82.0
HKD2_k127_8967821_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.472e-252 790.0
HKD2_k127_8967821_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 544.0
HKD2_k127_8967821_10 histone H2A K63-linked ubiquitination - - - 0.000000000001724 76.0
HKD2_k127_8967821_11 - - - - 0.00000000001174 78.0
HKD2_k127_8967821_2 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 414.0
HKD2_k127_8967821_3 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 316.0
HKD2_k127_8967821_4 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 346.0
HKD2_k127_8967821_5 Memo-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000325 261.0
HKD2_k127_8967821_6 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000003765 243.0
HKD2_k127_8967821_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000004872 183.0
HKD2_k127_8967821_8 Adenylate cyclase - - - 0.000000000000000003374 93.0
HKD2_k127_8967821_9 Hydrogenase maturation protease - - - 0.000000000000006342 85.0
HKD2_k127_8990403_0 PFAM LOR SDH bifunctional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 328.0
HKD2_k127_8990403_1 Aldehyde dehydrogenase family K00294,K13821 - 1.2.1.88,1.5.5.2 0.0000002077 52.0
HKD2_k127_8994199_0 Cellulase N-terminal ig-like domain - - - 0.0 1075.0
HKD2_k127_8994199_1 Belongs to the GarS family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 512.0
HKD2_k127_8994199_10 Major Facilitator Superfamily - - - 0.0000000000000002206 93.0
HKD2_k127_8994199_11 Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins - GO:0000166,GO:0003008,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006836,GO:0006950,GO:0006952,GO:0007600,GO:0007601,GO:0007610,GO:0007632,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0012505,GO:0015696,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0023051,GO:0030176,GO:0030544,GO:0030554,GO:0031072,GO:0031224,GO:0031227,GO:0031967,GO:0031975,GO:0031984,GO:0032501,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034260,GO:0034976,GO:0035639,GO:0036094,GO:0036211,GO:0042175,GO:0042578,GO:0042742,GO:0042802,GO:0042803,GO:0043086,GO:0043087,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044601,GO:0044602,GO:0044603,GO:0045117,GO:0046983,GO:0048519,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050829,GO:0050877,GO:0050896,GO:0050906,GO:0050908,GO:0050953,GO:0050962,GO:0051087,GO:0051179,GO:0051234,GO:0051336,GO:0051346,GO:0051606,GO:0051608,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0065009,GO:0070566,GO:0070733,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0080134,GO:0080135,GO:0097159,GO:0097367,GO:0098542,GO:0098827,GO:0140096,GO:1900101,GO:1901265,GO:1901363,GO:1901564,GO:1903894,GO:1905897 - 0.00000002316 64.0
HKD2_k127_8994199_2 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 426.0
HKD2_k127_8994199_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 334.0
HKD2_k127_8994199_4 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 317.0
HKD2_k127_8994199_5 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001426 257.0
HKD2_k127_8994199_6 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000008043 218.0
HKD2_k127_8994199_7 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000001065 155.0
HKD2_k127_8994199_8 GntR family transcriptional regulator K07979 - - 0.0000000000000000007532 91.0
HKD2_k127_8994199_9 serine-type aminopeptidase activity - - - 0.0000000000000002081 85.0
HKD2_k127_8995073_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006764 284.0
HKD2_k127_8995073_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002574 237.0
HKD2_k127_8995073_2 spore germination K07790 - - 0.0000000000000000000000000000000000000003537 159.0
HKD2_k127_9001815_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 370.0
HKD2_k127_9001815_1 Outer membrane efflux protein - - - 0.0000000006619 70.0
HKD2_k127_9005175_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 6.284e-243 764.0
HKD2_k127_9005175_1 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 589.0
HKD2_k127_9005175_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 599.0
HKD2_k127_9005175_3 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
HKD2_k127_9005175_4 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000005519 220.0
HKD2_k127_9005175_5 Cell shape determining protein MreB Mrl - - - 0.000000000000000000000000000000000000000000000000000007714 202.0
HKD2_k127_9005175_6 Domain of unknown function (DUF4342) - - - 0.0000000000318 67.0
HKD2_k127_9005175_7 Acetyltransferase (GNAT) family - - - 0.0000002394 62.0
HKD2_k127_9005175_8 Cytochrome c-type biogenesis protein K02200 - - 0.0002646 54.0
HKD2_k127_9015007_0 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 526.0
HKD2_k127_9015007_1 NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 419.0
HKD2_k127_9015007_2 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 414.0
HKD2_k127_9015007_3 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000006382 83.0
HKD2_k127_9017913_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001806 193.0
HKD2_k127_9017913_1 arylsulfatase A - - - 0.00000000000000000000000000000000000000000000009327 191.0
HKD2_k127_9042745_0 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 612.0
HKD2_k127_9042745_1 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 482.0
HKD2_k127_9042745_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 446.0
HKD2_k127_9042745_3 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 319.0
HKD2_k127_9042745_4 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000004404 236.0
HKD2_k127_9042745_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000006302 200.0
HKD2_k127_9042745_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000001326 125.0
HKD2_k127_9042745_7 - - - - 0.000000000000000000000000000002149 126.0
HKD2_k127_9042745_8 Protein of unknown function (DUF4013) - - - 0.0000000000000000001225 99.0
HKD2_k127_9042745_9 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.000000003353 60.0
HKD2_k127_9048206_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 8.3e-294 920.0
HKD2_k127_9048206_1 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 623.0
HKD2_k127_9048206_10 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000002541 81.0
HKD2_k127_9048206_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 482.0
HKD2_k127_9048206_3 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 357.0
HKD2_k127_9048206_4 PFAM phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006724 304.0
HKD2_k127_9048206_5 arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002691 269.0
HKD2_k127_9048206_6 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000006034 252.0
HKD2_k127_9048206_7 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001155 265.0
HKD2_k127_9048206_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000228 173.0
HKD2_k127_9048206_9 Male sterility protein - - - 0.000000000000000096 95.0
HKD2_k127_9069905_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 7.169e-279 882.0
HKD2_k127_9069905_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 381.0
HKD2_k127_9069905_10 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000001973 117.0
HKD2_k127_9069905_11 WD-40 repeat-containing protein K12132 - 2.7.11.1 0.000000000000000000002603 110.0
HKD2_k127_9069905_2 Allophanate hydrolase subunit 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 358.0
HKD2_k127_9069905_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 338.0
HKD2_k127_9069905_4 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 333.0
HKD2_k127_9069905_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 302.0
HKD2_k127_9069905_6 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001163 276.0
HKD2_k127_9069905_7 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001183 261.0
HKD2_k127_9069905_8 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000005935 194.0
HKD2_k127_9069905_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000001043 147.0
HKD2_k127_9082544_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1099.0
HKD2_k127_9082544_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004565 286.0
HKD2_k127_9082544_10 - - - - 0.0000001104 57.0
HKD2_k127_9082544_11 Sigma-70, region 4 K03088 - - 0.00005876 49.0
HKD2_k127_9082544_13 Psort location Periplasmic, score K05349 - 3.2.1.21 0.0007425 53.0
HKD2_k127_9082544_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000002147 196.0
HKD2_k127_9082544_3 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000007236 132.0
HKD2_k127_9082544_4 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000003624 126.0
HKD2_k127_9082544_5 - - - - 0.000000000000000004214 99.0
HKD2_k127_9082544_6 - - - - 0.000000000000000004231 91.0
HKD2_k127_9082544_8 SnoaL-like domain - - - 0.0000000000007579 77.0
HKD2_k127_9082544_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000001989 73.0
HKD2_k127_9111832_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 477.0
HKD2_k127_9111832_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000138 198.0
HKD2_k127_9111832_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000005612 194.0
HKD2_k127_9111832_3 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000001257 192.0
HKD2_k127_9111832_4 ribonuclease activity - - - 0.0000000000000000000000000001433 120.0
HKD2_k127_9111832_5 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000007303 98.0
HKD2_k127_9142510_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 555.0
HKD2_k127_9142510_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 519.0
HKD2_k127_9142510_2 TonB-dependent Receptor Plug - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 530.0
HKD2_k127_9142510_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 386.0
HKD2_k127_9142510_4 Carbohydrate-binding family 9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002299 251.0
HKD2_k127_9142510_5 BadF BadG BcrA BcrD ATPase family - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000004384 169.0
HKD2_k127_9142510_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000003854 162.0
HKD2_k127_9147364_0 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 389.0
HKD2_k127_9147364_1 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002961 278.0
HKD2_k127_9147364_2 Biotin-lipoyl like K02005,K13888 - - 0.000000000000000001855 96.0
HKD2_k127_9154503_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 2039.0
HKD2_k127_9154503_1 Oxidoreductase - - - 2.604e-261 815.0
HKD2_k127_9154503_10 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002675 255.0
HKD2_k127_9154503_11 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002084 237.0
HKD2_k127_9154503_12 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000001667 201.0
HKD2_k127_9154503_13 Enoyl-(Acyl carrier protein) reductase K00059,K18009,K19548 - 1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76 0.0000000000000000000000000000000000000000000000000000003499 220.0
HKD2_k127_9154503_14 Gluconate 2-dehydrogenase subunit 3 - - - 0.000000000000000000000000000000000000000000000001131 198.0
HKD2_k127_9154503_15 AP endonuclease family 2 C terminus - - - 0.0000000003816 72.0
HKD2_k127_9154503_16 Tetratricopeptide repeat - - - 0.00007244 48.0
HKD2_k127_9154503_2 ABC transporter K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 597.0
HKD2_k127_9154503_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 427.0
HKD2_k127_9154503_4 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 393.0
HKD2_k127_9154503_5 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 387.0
HKD2_k127_9154503_6 Branched-chain amino acid transport system / permease component K10440,K10553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 374.0
HKD2_k127_9154503_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 347.0
HKD2_k127_9154503_8 PFAM Amidohydrolase 2 K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 324.0
HKD2_k127_9154503_9 alpha-galactosidase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 326.0
HKD2_k127_9163977_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 8.961e-197 630.0
HKD2_k127_9163977_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 508.0
HKD2_k127_9163977_10 Trehalose utilisation K09992 - - 0.0000000000000000000000000000001458 139.0
HKD2_k127_9163977_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000001151 119.0
HKD2_k127_9163977_12 metal-dependent membrane protease K07052 - - 0.00001321 56.0
HKD2_k127_9163977_2 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 427.0
HKD2_k127_9163977_3 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 358.0
HKD2_k127_9163977_4 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 340.0
HKD2_k127_9163977_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 310.0
HKD2_k127_9163977_6 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000005534 261.0
HKD2_k127_9163977_7 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000002488 203.0
HKD2_k127_9163977_8 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000003368 181.0
HKD2_k127_9163977_9 Transporter associated domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000002493 169.0
HKD2_k127_9165280_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.706e-239 764.0
HKD2_k127_9165280_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.817e-224 705.0
HKD2_k127_9165280_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 359.0
HKD2_k127_9165280_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
HKD2_k127_9165280_4 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 356.0
HKD2_k127_9165280_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006477 335.0
HKD2_k127_9165280_6 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001587 282.0
HKD2_k127_9165280_7 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000001624 209.0
HKD2_k127_9165280_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000001691 76.0
HKD2_k127_9183007_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1608.0
HKD2_k127_9183007_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 573.0
HKD2_k127_9183007_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 483.0
HKD2_k127_9183007_3 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 436.0
HKD2_k127_9183007_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004149 251.0
HKD2_k127_9183007_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000002968 175.0
HKD2_k127_9183007_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000001961 126.0
HKD2_k127_9183007_7 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000003407 70.0
HKD2_k127_9183007_8 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000008877 71.0
HKD2_k127_9189520_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000003665 220.0
HKD2_k127_9189520_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000003374 191.0
HKD2_k127_9189520_2 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000005482 149.0
HKD2_k127_9189520_3 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000004111 105.0
HKD2_k127_9189520_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.000000000000005657 81.0
HKD2_k127_9189520_5 - - - - 0.00000000000143 82.0
HKD2_k127_9208833_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 627.0
HKD2_k127_9208833_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 383.0
HKD2_k127_9208833_2 CotH kinase protein - - - 0.000000000000000000000000000000000000000000000000000008228 211.0
HKD2_k127_9208833_3 PFAM Nicotinamide mononucleotide transporter PnuC K03811 - - 0.0000000000000000000000000000000000000000000000000008046 189.0
HKD2_k127_9208833_4 Domain of unknown function (DUF4956) - - - 0.0000000000000000000000000000000000001126 150.0
HKD2_k127_9208833_5 - - - - 0.00000000000000000000000000000000004637 156.0
HKD2_k127_9208833_6 AAA domain - - - 0.0000000000000000000000000000000001919 154.0
HKD2_k127_9208833_7 - - - - 0.000000000000000000000000000000132 128.0
HKD2_k127_9208833_8 phosphate ion binding - - - 0.000000000000000000001021 101.0
HKD2_k127_9229018_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 4.631e-251 792.0
HKD2_k127_9229018_1 MacB-like periplasmic core domain K02004 - - 2.782e-201 656.0
HKD2_k127_9229018_10 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000007469 241.0
HKD2_k127_9229018_11 LysM domain protein K07261 - - 0.00000000000000000000000000000000000000000000000000000000000000004085 238.0
HKD2_k127_9229018_12 3-methyladenine DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000001536 239.0
HKD2_k127_9229018_13 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000001343 210.0
HKD2_k127_9229018_14 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000005104 194.0
HKD2_k127_9229018_15 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000001496 162.0
HKD2_k127_9229018_16 PFAM Patatin K07001 - - 0.0000000000000000000000005081 115.0
HKD2_k127_9229018_17 protein-disulfide reductase activity - - - 0.00000000000000000009477 101.0
HKD2_k127_9229018_18 Bacterial regulatory protein, Fis family - - - 0.00001494 50.0
HKD2_k127_9229018_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 551.0
HKD2_k127_9229018_3 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 471.0
HKD2_k127_9229018_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 449.0
HKD2_k127_9229018_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 402.0
HKD2_k127_9229018_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 353.0
HKD2_k127_9229018_7 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 353.0
HKD2_k127_9229018_8 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 308.0
HKD2_k127_9229018_9 ATPases associated with a variety of cellular activities K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001641 254.0
HKD2_k127_9238484_0 DEAD DEAH box helicase - - - 0.0 1199.0
HKD2_k127_9238484_1 Hydrolase CocE NonD family - - - 1.456e-311 975.0
HKD2_k127_9238484_10 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 381.0
HKD2_k127_9238484_11 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 329.0
HKD2_k127_9238484_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002924 269.0
HKD2_k127_9238484_13 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003638 278.0
HKD2_k127_9238484_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003633 247.0
HKD2_k127_9238484_15 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000006864 68.0
HKD2_k127_9238484_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.157e-274 880.0
HKD2_k127_9238484_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.098e-225 707.0
HKD2_k127_9238484_4 DNA polymerase type-B family K02336 - 2.7.7.7 5.263e-197 639.0
HKD2_k127_9238484_5 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 576.0
HKD2_k127_9238484_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 573.0
HKD2_k127_9238484_7 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 532.0
HKD2_k127_9238484_8 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 436.0
HKD2_k127_9238484_9 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 421.0
HKD2_k127_9320171_0 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000002258 159.0
HKD2_k127_9320171_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000121 117.0
HKD2_k127_9320171_2 lysyltransferase activity K07027 - - 0.00000000000000000001205 104.0
HKD2_k127_9320171_3 Putative zinc-finger - GO:0005575,GO:0016020 - 0.0005363 51.0
HKD2_k127_9356761_0 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 325.0
HKD2_k127_9356761_1 GIY-YIG catalytic domain K07461 - - 0.0000000000000000001319 95.0
HKD2_k127_9356761_2 bacterial-type flagellum-dependent cell motility K03641 - - 0.0004035 45.0
HKD2_k127_9464523_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 548.0
HKD2_k127_9464523_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 315.0
HKD2_k127_9464523_10 Putative porin - - - 0.00000000000000009286 93.0
HKD2_k127_9464523_11 Protein kinase domain - - - 0.0000000000001494 81.0
HKD2_k127_9464523_12 - - - - 0.0000000000002924 84.0
HKD2_k127_9464523_14 Belongs to the peptidase S8 family - - - 0.00000006958 66.0
HKD2_k127_9464523_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 311.0
HKD2_k127_9464523_3 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 300.0
HKD2_k127_9464523_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000122 314.0
HKD2_k127_9464523_5 carbohydrate binding K21298 - 2.4.1.333 0.000000000000000000000000000000000000000000000000000000000000000000006057 263.0
HKD2_k127_9464523_6 - - - - 0.0000000000000000000000008695 107.0
HKD2_k127_9464523_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000436 110.0
HKD2_k127_9464523_8 ABC-2 family transporter protein K01992 - - 0.00000000000000000007351 104.0
HKD2_k127_9464523_9 - K01992,K19341 - - 0.000000000000000000198 103.0
HKD2_k127_9536832_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 304.0
HKD2_k127_9536832_1 RNA polymerase recycling family C-terminal K03580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006209 300.0
HKD2_k127_9536832_2 FHA domain - - - 0.000000000000000000000000000000000000000000007692 186.0
HKD2_k127_9536832_3 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000292 156.0
HKD2_k127_9536832_4 Alternative locus ID K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000005111 145.0
HKD2_k127_9536832_5 - - - - 0.00002439 47.0
HKD2_k127_9545056_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 467.0
HKD2_k127_9545056_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 374.0
HKD2_k127_9545056_2 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 365.0
HKD2_k127_9545056_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 301.0
HKD2_k127_9545056_4 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000003166 239.0
HKD2_k127_9545056_5 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000003296 235.0
HKD2_k127_9579487_0 flavin-nucleotide-binding protein structurally related to pyridoxine 5-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 509.0
HKD2_k127_9579487_1 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 513.0
HKD2_k127_9579487_2 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 360.0
HKD2_k127_9579487_3 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003555 253.0
HKD2_k127_9579487_4 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000008249 226.0
HKD2_k127_9579487_5 - - - - 0.000000000000000000000000000000001148 139.0
HKD2_k127_9579487_6 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000001107 104.0
HKD2_k127_9579487_7 pyridoxamine 5-phosphate - - - 0.0000000000000002231 85.0
HKD2_k127_9579487_8 aminopeptidase N K01256,K08776 - 3.4.11.2 0.0009278 52.0
HKD2_k127_9597242_0 Peptidase family M1 domain - - - 4.323e-255 800.0
HKD2_k127_9597242_1 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 505.0
HKD2_k127_9597242_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000001538 94.0
HKD2_k127_9597242_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.000007771 58.0
HKD2_k127_9597242_12 Transcriptional regulatory protein, C terminal - - - 0.000848 52.0
HKD2_k127_9597242_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 410.0
HKD2_k127_9597242_3 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 387.0
HKD2_k127_9597242_4 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 366.0
HKD2_k127_9597242_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 356.0
HKD2_k127_9597242_6 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000001875 231.0
HKD2_k127_9597242_7 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000004155 158.0
HKD2_k127_9597242_8 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000001353 134.0
HKD2_k127_9597242_9 response regulator, receiver - - - 0.0000000000000000000000001387 122.0
HKD2_k127_9608836_0 purine nucleobase transmembrane transporter activity K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 551.0
HKD2_k127_9608836_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 447.0
HKD2_k127_9608836_10 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000003631 164.0
HKD2_k127_9608836_11 PFAM Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000003774 145.0
HKD2_k127_9608836_12 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000006237 145.0
HKD2_k127_9608836_13 AAA domain - - - 0.000000000000000000000000002802 121.0
HKD2_k127_9608836_14 Protein involved in cellulose biosynthesis - - - 0.00000000000000000000000002801 123.0
HKD2_k127_9608836_15 O-Antigen Polymerase K02847 - - 0.000000000000000000000004251 120.0
HKD2_k127_9608836_16 metallopeptidase activity K15531,K19668,K20276 - 3.2.1.156,3.2.1.91 0.0000001432 59.0
HKD2_k127_9608836_17 Acetyltransferase (GNAT) domain - - - 0.00005834 50.0
HKD2_k127_9608836_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 399.0
HKD2_k127_9608836_3 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 397.0
HKD2_k127_9608836_4 PFAM WD40 domain protein beta Propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 396.0
HKD2_k127_9608836_5 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 338.0
HKD2_k127_9608836_6 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003102 271.0
HKD2_k127_9608836_7 Lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000224 247.0
HKD2_k127_9608836_8 deacetylase - - - 0.0000000000000000000000000000000000000000001449 183.0
HKD2_k127_9608836_9 MviN-like protein K03980 - - 0.0000000000000000000000000000000000000000009604 176.0
HKD2_k127_961221_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 527.0
HKD2_k127_961221_1 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 486.0
HKD2_k127_961221_10 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000004429 164.0
HKD2_k127_961221_11 WHG domain - - - 0.00000000000000000000000000000000000005326 150.0
HKD2_k127_961221_12 Domain of unknown function (DUF5107) - - - 0.00000000000000000000000000002161 134.0
HKD2_k127_961221_13 - - - - 0.0000000000000001281 93.0
HKD2_k127_961221_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 411.0
HKD2_k127_961221_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 395.0
HKD2_k127_961221_4 Psort location Cytoplasmic, score 8.87 K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
HKD2_k127_961221_5 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000197 301.0
HKD2_k127_961221_6 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006261 262.0
HKD2_k127_961221_7 serine-type peptidase activity K06978,K21105 - 3.1.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000002368 272.0
HKD2_k127_961221_8 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000002607 230.0
HKD2_k127_961221_9 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000003222 223.0
HKD2_k127_9628235_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 317.0
HKD2_k127_9628235_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000001342 55.0
HKD2_k127_9697760_0 PFAM Type II secretion system protein E K02652 - - 1.108e-211 665.0
HKD2_k127_9697760_1 Type ii and iii secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000211 305.0
HKD2_k127_9697760_2 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000007061 159.0
HKD2_k127_9697760_3 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000000000002465 123.0
HKD2_k127_9697760_4 Pilus assembly protein K02662 - - 0.00000000000000000003315 106.0
HKD2_k127_9716707_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 462.0
HKD2_k127_9716707_1 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 359.0
HKD2_k127_9716707_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000001577 245.0
HKD2_k127_9716707_3 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000001089 147.0
HKD2_k127_9741151_0 radical SAM domain protein K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 315.0
HKD2_k127_9741151_1 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000538 233.0
HKD2_k127_9741151_2 - - - - 0.0000000000000000000000000000000000000000000000000000000001044 225.0
HKD2_k127_9741151_3 - - - - 0.0000000000000656 87.0
HKD2_k127_9773069_0 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 238.0
HKD2_k127_9773069_1 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000009384 212.0
HKD2_k127_9773069_3 Putative adhesin - - - 0.00000000001995 74.0
HKD2_k127_9773069_4 Bacterial protein of unknown function (DUF882) - - - 0.000000004011 59.0
HKD2_k127_9773069_5 Tetratricopeptide repeat - - - 0.00000009628 63.0
HKD2_k127_9775183_0 polygalacturonase activity K01184 - 3.2.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 503.0
HKD2_k127_9775183_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 486.0
HKD2_k127_9775183_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000007293 159.0
HKD2_k127_9775183_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000004989 140.0
HKD2_k127_9775183_12 - - - - 0.0000000000002238 82.0
HKD2_k127_9775183_2 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 363.0
HKD2_k127_9775183_3 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 325.0
HKD2_k127_9775183_4 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 326.0
HKD2_k127_9775183_5 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 325.0
HKD2_k127_9775183_6 Domain of unknown function (DUF4861) - - - 0.000000000000000000000000000000000000000000000000000000000000000005047 241.0
HKD2_k127_9775183_7 COG4206 Outer membrane cobalamin receptor protein K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000006243 248.0
HKD2_k127_9775183_8 - - - - 0.00000000000000000000000000000000000000000000000000002655 201.0
HKD2_k127_9775183_9 Sortilin, neurotensin receptor 3, - - - 0.00000000000000000000000000000000000000000000000008551 184.0
HKD2_k127_9788144_0 response regulator, receiver K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 481.0
HKD2_k127_9788144_1 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 423.0
HKD2_k127_9788144_10 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000003306 156.0
HKD2_k127_9788144_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000001242 107.0
HKD2_k127_9788144_12 Peptidase family M28 - - - 0.0000000000000689 85.0
HKD2_k127_9788144_13 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0004087 55.0
HKD2_k127_9788144_2 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 355.0
HKD2_k127_9788144_3 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 338.0
HKD2_k127_9788144_4 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001199 278.0
HKD2_k127_9788144_5 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000001376 235.0
HKD2_k127_9788144_6 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000391 203.0
HKD2_k127_9788144_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000001351 181.0
HKD2_k127_9788144_8 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000002395 163.0
HKD2_k127_9788144_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000529 162.0
HKD2_k127_9797141_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005379 280.0
HKD2_k127_9797141_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009795 284.0
HKD2_k127_9797141_2 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000007099 132.0
HKD2_k127_9797141_3 - - - - 0.00000000000000000000000000000007154 133.0
HKD2_k127_9827664_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 524.0
HKD2_k127_9827664_1 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 510.0
HKD2_k127_9827664_2 chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000006601 231.0
HKD2_k127_9827664_3 Belongs to the 'phage' integrase family - - - 0.0000000000003417 77.0
HKD2_k127_9856074_0 AcrB/AcrD/AcrF family K07787,K15726 - - 1.262e-287 915.0
HKD2_k127_9856074_1 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 424.0
HKD2_k127_9856074_2 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 302.0
HKD2_k127_9856074_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000001965 189.0
HKD2_k127_9856074_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000006961 187.0
HKD2_k127_9856074_5 pyrroloquinoline quinone binding - - - 0.0000000000000006569 92.0
HKD2_k127_9856074_6 efflux transmembrane transporter activity K15725 - - 0.0000000001016 72.0
HKD2_k127_9954611_0 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 417.0
HKD2_k127_9954611_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000148 300.0
HKD2_k127_9954611_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000476 239.0
HKD2_k127_9954611_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000003866 223.0
HKD2_k127_9954611_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000001214 217.0
HKD2_k127_9954611_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000004986 201.0
HKD2_k127_9954611_6 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000000000002001 168.0
HKD2_k127_9954611_7 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000002617 127.0
HKD2_k127_9954611_8 ASPIC and UnbV - - - 0.00000000008885 70.0
HKD2_k127_9954611_9 COG0457 FOG TPR repeat - - - 0.00000000174 70.0
HKD2_k127_9978464_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 556.0
HKD2_k127_9978464_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001012 282.0
HKD2_k127_9978464_2 nuclear chromosome segregation - - - 0.0000000000000000000000000000000001123 145.0
HKD2_k127_9978464_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000002491 106.0
HKD2_k127_9978464_6 nuclear chromosome segregation - - - 0.0000000000004792 79.0
HKD2_k127_9978464_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000002488 73.0
HKD2_k127_9978464_8 salt-induced outer membrane protein K07283 - - 0.00000002709 65.0
HKD2_k127_9983711_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 581.0
HKD2_k127_9983711_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 456.0
HKD2_k127_9983711_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000266 117.0
HKD2_k127_9983711_11 Putative regulatory protein - - - 0.0000000007819 62.0
HKD2_k127_9983711_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 443.0
HKD2_k127_9983711_3 Major facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 392.0
HKD2_k127_9983711_4 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 364.0
HKD2_k127_9983711_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001063 258.0
HKD2_k127_9983711_6 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000006657 198.0
HKD2_k127_9983711_7 - - - - 0.0000000000000000000000000000000000001151 151.0
HKD2_k127_9983711_8 Protein of unknown function (DUF1579) - - - 0.0000000000000000000000000000000000001949 147.0
HKD2_k127_9983711_9 - - - - 0.00000000000000000000000000008213 135.0