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Overview

ID MAG01781
Name HKD2_bin.22
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class WTBG01
Order WTBG01
Family WTBG01
Genus CALJBY01
Species
Assembly information
Completeness (%) 60.73
Contamination (%) 0.56
GC content (%) 55.0
N50 (bp) 5,789
Genome size (bp) 1,418,158

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1331

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_1009830_0 Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 361.0
HKD2_k127_1009830_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000001281 230.0
HKD2_k127_1009830_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000009579 205.0
HKD2_k127_1009830_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000001186 163.0
HKD2_k127_1009830_4 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000003059 144.0
HKD2_k127_1009830_5 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.00000000003329 74.0
HKD2_k127_1009830_6 energy transducer activity K03646,K03832 - - 0.00001876 55.0
HKD2_k127_10113297_0 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000002149 249.0
HKD2_k127_10113297_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000005528 225.0
HKD2_k127_10113297_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000002886 63.0
HKD2_k127_10187897_0 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 454.0
HKD2_k127_10187897_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 441.0
HKD2_k127_10187897_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000005834 269.0
HKD2_k127_10187897_3 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000009177 169.0
HKD2_k127_10187897_4 anaerobic cobalt chelatase K02190 - 4.99.1.3 0.00007059 52.0
HKD2_k127_1049841_0 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 451.0
HKD2_k127_1049841_1 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 335.0
HKD2_k127_1049841_2 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 315.0
HKD2_k127_1049841_3 PFAM regulatory protein TetR K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000002382 240.0
HKD2_k127_109142_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 460.0
HKD2_k127_109142_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000172 243.0
HKD2_k127_109142_2 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000122 197.0
HKD2_k127_109142_3 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000001087 162.0
HKD2_k127_1159643_0 Hsp70 protein - - - 9.403e-221 710.0
HKD2_k127_1159643_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K09384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 298.0
HKD2_k127_1214673_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 336.0
HKD2_k127_1214673_1 antr2,pht4 K08193 GO:0003674,GO:0005215,GO:0005315,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0006721,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0008643,GO:0009507,GO:0009526,GO:0009528,GO:0009536,GO:0009706,GO:0009941,GO:0009987,GO:0010028,GO:0015075,GO:0015144,GO:0015145,GO:0015229,GO:0015291,GO:0015318,GO:0015711,GO:0015749,GO:0015849,GO:0015882,GO:0016020,GO:0016021,GO:0016108,GO:0016116,GO:0016122,GO:0019866,GO:0022804,GO:0022857,GO:0031090,GO:0031224,GO:0031967,GO:0031969,GO:0031975,GO:0034219,GO:0034220,GO:0035461,GO:0042170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044425,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046942,GO:0046943,GO:0051119,GO:0051179,GO:0051180,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0090482,GO:0098656,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 334.0
HKD2_k127_1214673_2 peptidase U32 - - - 0.0000000000000000000000000004576 117.0
HKD2_k127_1289198_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 458.0
HKD2_k127_1289198_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000009106 173.0
HKD2_k127_1289198_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000003483 124.0
HKD2_k127_1290462_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 578.0
HKD2_k127_1290462_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000003403 253.0
HKD2_k127_1304018_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 601.0
HKD2_k127_1304018_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 456.0
HKD2_k127_1304018_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
HKD2_k127_1304018_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000002619 149.0
HKD2_k127_1304018_4 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000002344 147.0
HKD2_k127_1304018_5 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000007578 134.0
HKD2_k127_1304018_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.000000000204 63.0
HKD2_k127_1304018_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000008726 57.0
HKD2_k127_1304018_8 Evidence 5 No homology to any previously reported sequences - - - 0.0000000325 59.0
HKD2_k127_1304018_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000007923 49.0
HKD2_k127_1336092_0 Belongs to the RtcB family K14415 - 6.5.1.3 5.65e-210 663.0
HKD2_k127_1336092_1 RNB K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 423.0
HKD2_k127_1336092_2 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 357.0
HKD2_k127_1336092_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
HKD2_k127_1336092_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000003172 192.0
HKD2_k127_1336092_5 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000008425 123.0
HKD2_k127_1336092_7 Nucleoside-triphosphatase, cancer-related K06928 - 3.6.1.15 0.00000000007685 65.0
HKD2_k127_1349631_0 Conserved protein K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001016 282.0
HKD2_k127_1349631_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000001372 224.0
HKD2_k127_1349631_2 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000000000000000000000000000000000000000002308 172.0
HKD2_k127_1349631_3 cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000001579 172.0
HKD2_k127_1349631_4 - - - - 0.00003666 47.0
HKD2_k127_1405101_0 Glycosyl transferase family 21 - - - 1.871e-303 966.0
HKD2_k127_1405101_1 (ABC) transporter K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 621.0
HKD2_k127_1405101_2 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 413.0
HKD2_k127_1405101_3 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 399.0
HKD2_k127_1405101_5 Tetratricopeptide repeat - - - 0.00000000001299 76.0
HKD2_k127_1405101_6 SMART Rhodanese domain protein - - - 0.0001268 44.0
HKD2_k127_1423671_0 GXGXG motif - - - 0.0 1170.0
HKD2_k127_1423671_1 Conserved region in glutamate synthase - - - 2.554e-270 838.0
HKD2_k127_1423671_10 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000343 154.0
HKD2_k127_1423671_11 lytic transglycosylase activity - - - 0.000000000000000000001058 108.0
HKD2_k127_1423671_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 6.67e-215 674.0
HKD2_k127_1423671_3 Asparagine synthase K01953 - 6.3.5.4 1.055e-204 656.0
HKD2_k127_1423671_4 Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 593.0
HKD2_k127_1423671_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 590.0
HKD2_k127_1423671_6 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 468.0
HKD2_k127_1423671_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 382.0
HKD2_k127_1423671_8 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 332.0
HKD2_k127_1423671_9 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000005575 236.0
HKD2_k127_1435920_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 471.0
HKD2_k127_1435920_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 297.0
HKD2_k127_1435920_2 SMART Rhodanese domain protein - - - 0.00001262 49.0
HKD2_k127_1453481_0 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 313.0
HKD2_k127_1453481_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000336 271.0
HKD2_k127_1453481_2 PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000006024 224.0
HKD2_k127_1460444_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.731e-276 863.0
HKD2_k127_1460444_1 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000004229 184.0
HKD2_k127_1460444_2 metallopeptidase activity - - - 0.000007319 55.0
HKD2_k127_1462092_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 335.0
HKD2_k127_1462092_1 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 342.0
HKD2_k127_1462092_2 Cyclophilin-like K09143 - - 0.000000000000000000000000000000001374 135.0
HKD2_k127_1462092_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000002798 128.0
HKD2_k127_1462092_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000006384 83.0
HKD2_k127_1471073_0 Protein export membrane protein K03296,K18138 - - 0.0 1398.0
HKD2_k127_1471073_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 334.0
HKD2_k127_1471073_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000006214 120.0
HKD2_k127_1492825_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 515.0
HKD2_k127_1492825_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 372.0
HKD2_k127_1492825_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000003139 195.0
HKD2_k127_1492825_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000002969 114.0
HKD2_k127_1496146_0 Extracellular solute-binding protein, family 5 - - - 6.737e-237 754.0
HKD2_k127_1496146_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 7.215e-215 686.0
HKD2_k127_1496146_2 transport systems K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 420.0
HKD2_k127_1496146_3 PFAM Binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 416.0
HKD2_k127_1496146_4 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000008765 107.0
HKD2_k127_1496146_5 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000001118 98.0
HKD2_k127_1496146_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000002927 68.0
HKD2_k127_1496294_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 608.0
HKD2_k127_1496294_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000008605 242.0
HKD2_k127_1496294_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000001821 171.0
HKD2_k127_1496294_3 short-chain dehydrogenase reductase K00059 - 1.1.1.100 0.00000000002526 64.0
HKD2_k127_1496294_4 nucleosidase K01239,K01243 - 3.2.2.1,3.2.2.9 0.00000000009884 70.0
HKD2_k127_1542894_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 561.0
HKD2_k127_1542894_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004895 278.0
HKD2_k127_1542894_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 258.0
HKD2_k127_1542894_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000002962 123.0
HKD2_k127_1542894_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000002473 107.0
HKD2_k127_1562314_0 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000001567 188.0
HKD2_k127_1562314_1 Pfam Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000002164 162.0
HKD2_k127_1562314_2 PFAM oxidoreductase nitrogenase, component 1 K02587 - - 0.0000000000000001194 85.0
HKD2_k127_1562314_3 Uncharacterised ArCR, COG2043 - - - 0.000001111 59.0
HKD2_k127_1584249_0 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 398.0
HKD2_k127_1584249_1 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 317.0
HKD2_k127_1584249_2 - - - - 0.0000000002557 69.0
HKD2_k127_1594767_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 302.0
HKD2_k127_1594767_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000294 285.0
HKD2_k127_1594767_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000007067 163.0
HKD2_k127_1594767_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000001899 57.0
HKD2_k127_1598433_0 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 461.0
HKD2_k127_1598433_1 mandelate racemase muconate lactonizing K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 434.0
HKD2_k127_1598433_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 348.0
HKD2_k127_1598433_3 PFAM Rh family protein ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000009735 212.0
HKD2_k127_1598433_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000004005 177.0
HKD2_k127_1598433_5 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin K05370 - 1.3.7.3 0.000001078 59.0
HKD2_k127_1598433_6 - - - - 0.00001125 51.0
HKD2_k127_1611050_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.134e-196 621.0
HKD2_k127_1611050_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 559.0
HKD2_k127_1611050_2 4 iron, 4 sulfur cluster binding K18356 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000000001976 216.0
HKD2_k127_1658939_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 419.0
HKD2_k127_1658939_1 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000001047 197.0
HKD2_k127_1658939_2 PFAM Cytochrome c bacterial - - - 0.0004873 46.0
HKD2_k127_1825646_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 509.0
HKD2_k127_1825646_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 404.0
HKD2_k127_1825646_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000001114 188.0
HKD2_k127_1825646_3 Bacterial regulatory protein, Fis family K02667 - - 0.000000002117 64.0
HKD2_k127_1882207_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 385.0
HKD2_k127_1882207_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001875 274.0
HKD2_k127_1882207_2 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000003717 201.0
HKD2_k127_1882207_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000003408 132.0
HKD2_k127_1906250_0 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000005087 192.0
HKD2_k127_1906250_1 - - - - 0.000000000000000000000000000000000000000000000000002724 189.0
HKD2_k127_1906250_2 - - - - 0.00000000000000000000000000000000000000000001271 177.0
HKD2_k127_1906250_3 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000002401 101.0
HKD2_k127_1906250_4 NADPH-dependent FMN reductase - - - 0.0000000000000000003335 97.0
HKD2_k127_1906250_5 Flavodoxin-like fold K00355,K11748 - 1.6.5.2 0.0000000000000000008201 88.0
HKD2_k127_1906250_6 cellulose binding - - - 0.0000000002409 63.0
HKD2_k127_19086_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 574.0
HKD2_k127_19086_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 330.0
HKD2_k127_19086_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000003118 89.0
HKD2_k127_2001886_0 DNA polymerase K02347 - - 6.835e-196 627.0
HKD2_k127_2001886_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000009971 165.0
HKD2_k127_202047_0 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 461.0
HKD2_k127_202047_1 PFAM Glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 436.0
HKD2_k127_202047_2 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.0002496 43.0
HKD2_k127_210849_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1018.0
HKD2_k127_210849_1 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 401.0
HKD2_k127_210849_10 Hsp20/alpha crystallin family - - - 0.00000000000000000000008069 105.0
HKD2_k127_210849_11 - - - - 0.0000000000000000004419 91.0
HKD2_k127_210849_12 cellulose binding K13735 - - 0.000000000000003576 77.0
HKD2_k127_210849_13 Iron only hydrogenase large subunit, C-terminal domain - - - 0.00000001195 59.0
HKD2_k127_210849_14 Ribbon-helix-helix domain - - - 0.0007936 44.0
HKD2_k127_210849_2 Mediates zinc uptake. May also transport other divalent cations K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 378.0
HKD2_k127_210849_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 369.0
HKD2_k127_210849_4 PFAM catalytic domain of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002223 292.0
HKD2_k127_210849_5 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000537 245.0
HKD2_k127_210849_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000001396 225.0
HKD2_k127_210849_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000108 222.0
HKD2_k127_210849_8 Major facilitator superfamily K08151 - - 0.00000000000000000000000000000000000000000000003627 177.0
HKD2_k127_210849_9 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000487 152.0
HKD2_k127_215437_0 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 313.0
HKD2_k127_215437_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000006996 237.0
HKD2_k127_215437_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000006298 171.0
HKD2_k127_215437_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000002426 130.0
HKD2_k127_215437_4 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000000000000001431 116.0
HKD2_k127_215437_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000002786 55.0
HKD2_k127_2354649_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005783 276.0
HKD2_k127_2354649_1 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002259 258.0
HKD2_k127_2354649_2 YHS domain - - - 0.00000000000000000000001062 103.0
HKD2_k127_2354649_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000000000000001245 97.0
HKD2_k127_2354649_4 PFAM thiamineS protein - - - 0.00000000001004 67.0
HKD2_k127_2354649_5 cytochrome c - - - 0.00003554 49.0
HKD2_k127_2396148_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 395.0
HKD2_k127_2396148_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 341.0
HKD2_k127_241402_0 Epimerase dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 389.0
HKD2_k127_241402_1 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 314.0
HKD2_k127_241402_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000008602 264.0
HKD2_k127_241402_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000007334 140.0
HKD2_k127_241402_4 - - - - 0.0000000000008795 81.0
HKD2_k127_2597230_0 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 576.0
HKD2_k127_2597230_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 348.0
HKD2_k127_2597230_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004876 276.0
HKD2_k127_2597230_3 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000002362 162.0
HKD2_k127_2621297_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 6.046e-276 857.0
HKD2_k127_2621297_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 495.0
HKD2_k127_2621297_2 Transaldolase/Fructose-6-phosphate aldolase - - - 0.000000000000000000000000000000000000000000000002047 178.0
HKD2_k127_2692399_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 462.0
HKD2_k127_2692399_1 cysteine-tRNA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 422.0
HKD2_k127_2692399_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 329.0
HKD2_k127_2692399_3 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002898 284.0
HKD2_k127_2692399_4 lipid binding K03098 - - 0.0000000000000000000000000000000000000000000006868 173.0
HKD2_k127_2692399_5 lycopene cyclase - - - 0.0000000000000001362 84.0
HKD2_k127_2692399_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000887 73.0
HKD2_k127_2692399_7 lycopene cyclase - - - 0.00003522 46.0
HKD2_k127_2707656_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.847e-243 771.0
HKD2_k127_2707656_1 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 406.0
HKD2_k127_2707656_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000122 121.0
HKD2_k127_2707656_3 ribosomal RNA large subunit methyltransferase J K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.000158 44.0
HKD2_k127_271141_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 484.0
HKD2_k127_271141_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 436.0
HKD2_k127_271141_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 424.0
HKD2_k127_271141_3 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00007138 47.0
HKD2_k127_2725961_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 376.0
HKD2_k127_2725961_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000002565 260.0
HKD2_k127_2725961_2 O-methyltransferase, family 2 - - - 0.000000002576 62.0
HKD2_k127_2826109_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.159e-274 850.0
HKD2_k127_2826109_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000009327 172.0
HKD2_k127_2826109_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000004461 158.0
HKD2_k127_2826109_3 RadC-like JAB domain K03630 - - 0.0000000006455 60.0
HKD2_k127_2847943_0 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 323.0
HKD2_k127_2847943_1 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000001847 181.0
HKD2_k127_2847943_2 Radical SAM - - - 0.000000000000000000000000004146 117.0
HKD2_k127_2847943_3 PLD-like domain - - - 0.00000000000000000002157 98.0
HKD2_k127_2857621_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 8.057e-317 981.0
HKD2_k127_2857621_1 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 5.411e-223 703.0
HKD2_k127_2857621_2 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004009 251.0
HKD2_k127_2857621_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000002837 240.0
HKD2_k127_2857621_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000002333 91.0
HKD2_k127_2857621_5 Pfam:Pyridox_oxidase - - - 0.00000000002955 71.0
HKD2_k127_2857621_6 - - - - 0.000184 51.0
HKD2_k127_2862944_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 399.0
HKD2_k127_2862944_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000002708 226.0
HKD2_k127_2862944_2 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000001735 218.0
HKD2_k127_2862944_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000002633 156.0
HKD2_k127_2896931_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 602.0
HKD2_k127_295570_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1062.0
HKD2_k127_295570_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9.282e-294 917.0
HKD2_k127_295570_2 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000003187 214.0
HKD2_k127_2982603_0 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 374.0
HKD2_k127_2982603_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000007774 148.0
HKD2_k127_2982603_2 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000003303 75.0
HKD2_k127_2982603_3 Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin K05370 - 1.3.7.3 0.000001965 59.0
HKD2_k127_2982603_4 CAAX protease self-immunity - - - 0.000005818 56.0
HKD2_k127_2985698_0 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 359.0
HKD2_k127_2985698_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 313.0
HKD2_k127_2985698_2 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000003868 255.0
HKD2_k127_2985698_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000004001 188.0
HKD2_k127_2985698_4 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000002941 121.0
HKD2_k127_3050552_0 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 433.0
HKD2_k127_3050552_1 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 431.0
HKD2_k127_3050552_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 301.0
HKD2_k127_3050552_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124,K21308 - - 0.0000000000000000000000000000000000001608 145.0
HKD2_k127_3050552_4 CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0022607,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.0000000000000000000000000004871 116.0
HKD2_k127_3050552_5 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000073 109.0
HKD2_k127_3050552_6 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000008685 85.0
HKD2_k127_3050552_7 cell division protein - - - 0.000000743 59.0
HKD2_k127_3076407_0 Belongs to the citrate synthase family K01647 GO:0003674,GO:0003824,GO:0004108,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0036440,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.1 6.511e-195 618.0
HKD2_k127_3076407_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 307.0
HKD2_k127_3076407_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000006396 125.0
HKD2_k127_3077471_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 1.488e-280 874.0
HKD2_k127_3077471_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 539.0
HKD2_k127_3077471_2 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.00000000000000000000000000000001422 140.0
HKD2_k127_3077471_3 Bacterial regulatory proteins, tetR family - - - 0.00000000001019 72.0
HKD2_k127_3090727_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002503 277.0
HKD2_k127_3090727_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000001162 153.0
HKD2_k127_3090727_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K00441,K00528,K03522,K03616 - 1.12.98.1,1.18.1.2,1.19.1.1 0.0000000000000000000003912 104.0
HKD2_k127_3119039_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 451.0
HKD2_k127_3119039_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000118 239.0
HKD2_k127_3119039_2 Uncharacterised ArCR, COG2043 - - - 0.0000000002409 70.0
HKD2_k127_315973_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 454.0
HKD2_k127_315973_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 421.0
HKD2_k127_315973_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000009142 197.0
HKD2_k127_315973_3 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000002071 176.0
HKD2_k127_315973_4 3-dehydroquinate dehydratase activity K00014,K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.000000000000000000000000001947 113.0
HKD2_k127_3193334_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000005156 210.0
HKD2_k127_3193334_1 PFAM Nitroreductase - - - 0.000000000000000000000000000006686 127.0
HKD2_k127_3193334_2 Isochorismatase family - - - 0.00000000000000000000000000002423 125.0
HKD2_k127_3193334_3 Major facilitator superfamily - - - 0.000000000000000000000005489 111.0
HKD2_k127_3203390_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000289 229.0
HKD2_k127_3203390_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000001076 228.0
HKD2_k127_3203390_2 Putative regulatory protein - - - 0.0000000000000002168 81.0
HKD2_k127_321773_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000001626 152.0
HKD2_k127_321773_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000001573 113.0
HKD2_k127_321773_2 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000004291 107.0
HKD2_k127_3240399_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 451.0
HKD2_k127_3240399_1 Phospholipase D. Active site motifs. - - - 0.00000000000000000000000000000000000007841 151.0
HKD2_k127_3240399_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000006165 85.0
HKD2_k127_3240399_3 - - - - 0.0000029 58.0
HKD2_k127_3450397_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 476.0
HKD2_k127_3450397_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 361.0
HKD2_k127_3450397_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 343.0
HKD2_k127_3450397_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004816 259.0
HKD2_k127_3453283_0 BadF BadG BcrA BcrD - - - 0.0 1599.0
HKD2_k127_3453283_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 374.0
HKD2_k127_3453283_2 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 291.0
HKD2_k127_3453283_3 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001736 261.0
HKD2_k127_3453283_4 tigr00255 - - - 0.000000000000000000000000000000000000000000000000000000000009318 218.0
HKD2_k127_3453283_5 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000000000009121 189.0
HKD2_k127_3455374_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001454 295.0
HKD2_k127_3455374_1 cyclic diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000005293 225.0
HKD2_k127_3455374_2 lyase activity - - - 0.000000000000000000000000000000000000005253 167.0
HKD2_k127_3455374_3 - - - - 0.0000000000000000000001032 106.0
HKD2_k127_3455374_4 - - - - 0.0000000000000000009492 91.0
HKD2_k127_3455374_5 stress protein (general stress protein 26) - - - 0.000000000000009863 81.0
HKD2_k127_3463715_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 448.0
HKD2_k127_3463715_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 312.0
HKD2_k127_3463715_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 316.0
HKD2_k127_3463715_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008842 273.0
HKD2_k127_3463715_4 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000000000000000000000000000000000000000003025 196.0
HKD2_k127_3463715_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000008998 129.0
HKD2_k127_3463715_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000002582 71.0
HKD2_k127_3463715_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000002005 63.0
HKD2_k127_3475345_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 568.0
HKD2_k127_3475345_1 cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 447.0
HKD2_k127_3475345_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 348.0
HKD2_k127_3475345_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 325.0
HKD2_k127_3475345_4 MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000003101 196.0
HKD2_k127_3475345_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000004963 156.0
HKD2_k127_3475345_6 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21562 - - 0.0000000000000000000000000001353 124.0
HKD2_k127_3475345_7 radical SAM domain protein - - - 0.000000000004889 73.0
HKD2_k127_349154_0 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 317.0
HKD2_k127_349154_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000009981 205.0
HKD2_k127_349154_2 flavodoxin nitric oxide synthase - - - 0.00000000000002088 75.0
HKD2_k127_349154_3 Flavin reductase like domain - - - 0.0000000000001949 71.0
HKD2_k127_3552950_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 1.029e-266 825.0
HKD2_k127_3552950_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000006906 190.0
HKD2_k127_3552950_2 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000505 123.0
HKD2_k127_3552977_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 388.0
HKD2_k127_3552977_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 372.0
HKD2_k127_3552977_2 Jag_N K06346 - - 0.0000000000000000000000000000000000000000000002896 175.0
HKD2_k127_3552977_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000003202 111.0
HKD2_k127_3552977_4 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000002426 94.0
HKD2_k127_3552977_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000001977 93.0
HKD2_k127_3552977_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000002437 67.0
HKD2_k127_3629425_0 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 417.0
HKD2_k127_3629425_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008982 281.0
HKD2_k127_3629425_2 Alpha/beta hydrolase family - - - 0.0006506 52.0
HKD2_k127_363136_0 Glycoside hydrolase family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000694 280.0
HKD2_k127_363136_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000671 104.0
HKD2_k127_366022_0 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 530.0
HKD2_k127_366022_1 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 410.0
HKD2_k127_366022_10 Flavodoxin domain K00230 - 1.3.5.3 0.000000000001454 79.0
HKD2_k127_366022_11 Belongs to the HY2 family K05369 - 1.3.7.2 0.0002429 52.0
HKD2_k127_366022_2 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 342.0
HKD2_k127_366022_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 334.0
HKD2_k127_366022_4 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 282.0
HKD2_k127_366022_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000338 258.0
HKD2_k127_366022_6 FAD binding domain - - - 0.00000000000000000000000000000000001465 152.0
HKD2_k127_366022_7 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000008645 113.0
HKD2_k127_366022_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000001513 117.0
HKD2_k127_366022_9 PFAM regulatory protein TetR - - - 0.00000000000000007266 89.0
HKD2_k127_3720500_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 392.0
HKD2_k127_3720500_1 Ribosomal protein L13 K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005613 201.0
HKD2_k127_3720500_2 structural constituent of ribosome K02996 - - 0.00000000000000000000000000000000000000000001458 165.0
HKD2_k127_3720500_3 Poly A polymerase head domain K00970 - 2.7.7.19 0.0000000000000000000004723 104.0
HKD2_k127_376721_0 Amino acid permease - - - 7.047e-258 807.0
HKD2_k127_376721_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 6.091e-214 681.0
HKD2_k127_376721_2 PFAM response regulator receiver K11384 - - 1.024e-208 657.0
HKD2_k127_376721_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002407 291.0
HKD2_k127_376721_4 Pyridoxamine 5'-phosphate - - - 0.0000004516 59.0
HKD2_k127_3854055_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00184 - - 3.011e-218 704.0
HKD2_k127_3854055_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 438.0
HKD2_k127_3868444_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 454.0
HKD2_k127_3868444_1 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001621 253.0
HKD2_k127_3868444_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000003084 178.0
HKD2_k127_3868444_3 denitrification pathway - - - 0.00000000000000000000000000000000000000001034 177.0
HKD2_k127_3868444_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000006503 168.0
HKD2_k127_3868444_5 NHL repeat - - - 0.000000000000000000000000000000003878 131.0
HKD2_k127_3872292_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.119e-263 824.0
HKD2_k127_3872292_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 476.0
HKD2_k127_3872292_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
HKD2_k127_3872292_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 303.0
HKD2_k127_3872292_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000003671 256.0
HKD2_k127_3872292_5 YbbR-like protein - - - 0.00000000000000000000000000000001043 139.0
HKD2_k127_3872292_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000004252 62.0
HKD2_k127_3877306_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 6.657e-246 771.0
HKD2_k127_3877306_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 572.0
HKD2_k127_3877306_10 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000001228 233.0
HKD2_k127_3877306_11 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000002216 229.0
HKD2_k127_3877306_12 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000001186 219.0
HKD2_k127_3877306_13 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000001226 181.0
HKD2_k127_3877306_14 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000007377 165.0
HKD2_k127_3877306_15 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000002931 167.0
HKD2_k127_3877306_16 Ferredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.000000000000000000001286 95.0
HKD2_k127_3877306_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 533.0
HKD2_k127_3877306_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 428.0
HKD2_k127_3877306_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 354.0
HKD2_k127_3877306_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 327.0
HKD2_k127_3877306_6 Ribosomal protein S2 K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 326.0
HKD2_k127_3877306_7 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 320.0
HKD2_k127_3877306_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007979 286.0
HKD2_k127_3877306_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007332 256.0
HKD2_k127_3885683_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1685.0
HKD2_k127_3885683_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 527.0
HKD2_k127_3885683_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 514.0
HKD2_k127_3885683_3 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 340.0
HKD2_k127_3885683_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002041 231.0
HKD2_k127_3885683_5 4Fe-4S dicluster domain K14091 - - 0.000000000000000000000000000000000000000003101 157.0
HKD2_k127_3926512_0 PFAM Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 471.0
HKD2_k127_3926512_1 Flavodoxin-like fold - - - 0.00000000000000002428 93.0
HKD2_k127_3926512_2 Transcriptional regulator - - - 0.0000000000000001689 85.0
HKD2_k127_3953528_0 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 381.0
HKD2_k127_3953528_1 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000007429 261.0
HKD2_k127_4008162_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000001436 217.0
HKD2_k127_4008162_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000009906 201.0
HKD2_k127_4008162_2 PFAM Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000005117 194.0
HKD2_k127_4008162_3 anaerobic cobalt chelatase K02190 - 4.99.1.3 0.000000000518 68.0
HKD2_k127_4048455_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 539.0
HKD2_k127_4048455_1 sulfate adenylyltransferase K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 500.0
HKD2_k127_4048455_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 413.0
HKD2_k127_4048455_3 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 402.0
HKD2_k127_4048455_4 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 294.0
HKD2_k127_4048455_5 type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.00001088 51.0
HKD2_k127_4062181_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 577.0
HKD2_k127_4062181_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000001128 188.0
HKD2_k127_4062181_2 LeuA allosteric (dimerisation) domain K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000001017 166.0
HKD2_k127_4066069_0 Flavodoxin domain K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000001009 233.0
HKD2_k127_4066069_1 Sigma-70 factor, region 1.1 K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000003569 245.0
HKD2_k127_4066069_2 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000002201 176.0
HKD2_k127_4066069_3 Sugar (and other) transporter - - - 0.00000000000000000000591 94.0
HKD2_k127_41482_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 602.0
HKD2_k127_41482_1 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 263.0
HKD2_k127_41482_2 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001564 151.0
HKD2_k127_41482_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000008232 111.0
HKD2_k127_4156470_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 537.0
HKD2_k127_4156470_1 FAD binding domain - - - 0.0000000715 55.0
HKD2_k127_4165884_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 405.0
HKD2_k127_4165884_1 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000001031 196.0
HKD2_k127_4165884_2 - - - - 0.0000102 55.0
HKD2_k127_4169532_0 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 471.0
HKD2_k127_4169532_1 WYL domain K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002471 258.0
HKD2_k127_4169532_2 FAD binding domain - - - 0.000000000000000000000001853 118.0
HKD2_k127_4171467_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 550.0
HKD2_k127_4171467_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 526.0
HKD2_k127_4171467_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 478.0
HKD2_k127_4171467_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 346.0
HKD2_k127_4171467_4 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000008996 272.0
HKD2_k127_4171467_5 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000002476 203.0
HKD2_k127_4171467_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000773 119.0
HKD2_k127_4198066_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 376.0
HKD2_k127_4198066_1 PFAM Transketolase K21417 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 321.0
HKD2_k127_4198066_2 COG3264 Small-conductance mechanosensitive channel K22051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003708 276.0
HKD2_k127_4198066_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000007297 225.0
HKD2_k127_4217851_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 363.0
HKD2_k127_4217851_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 330.0
HKD2_k127_4217851_2 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000003628 198.0
HKD2_k127_4217851_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000001033 169.0
HKD2_k127_4217851_4 NUDIX domain - - - 0.0000000000000000000000000000000000001025 149.0
HKD2_k127_4217851_5 Domain of unknown function (DUF362) - - - 0.000000000000000000001856 105.0
HKD2_k127_4217851_6 Major Facilitator Superfamily - - - 0.000000000003472 76.0
HKD2_k127_4217851_7 Putative zinc-finger - - - 0.0004091 51.0
HKD2_k127_4264905_0 Exporters of the RND superfamily K07003 - - 2.102e-303 949.0
HKD2_k127_4264905_1 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 344.0
HKD2_k127_4264905_2 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 305.0
HKD2_k127_4264905_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004885 265.0
HKD2_k127_4268790_0 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 335.0
HKD2_k127_4268790_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 342.0
HKD2_k127_4268790_2 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000002715 265.0
HKD2_k127_4269268_0 Bacterial capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 302.0
HKD2_k127_4269268_1 FAD binding domain K00104 - 1.1.3.15 0.0000000000000000000000000001087 132.0
HKD2_k127_4269268_2 P60 family K21471 - - 0.00000000000000000001191 106.0
HKD2_k127_4304580_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 411.0
HKD2_k127_4304580_1 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000000000000000000000000000000000000000007838 177.0
HKD2_k127_4315617_0 Belongs to the selenophosphate synthase 1 family. Class I subfamily K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 449.0
HKD2_k127_4315617_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 322.0
HKD2_k127_4315617_10 - - - - 0.0000004588 55.0
HKD2_k127_4315617_11 Molybdopterin converting factor, small subunit K03636 - - 0.000007264 52.0
HKD2_k127_4315617_12 von Willebrand factor, type A K07114 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0001126 56.0
HKD2_k127_4315617_2 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 307.0
HKD2_k127_4315617_3 Amino acid permease K16238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 309.0
HKD2_k127_4315617_4 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000618 269.0
HKD2_k127_4315617_5 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000002016 224.0
HKD2_k127_4315617_6 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.0000000000000000000000007571 109.0
HKD2_k127_4315617_7 COG COG0714 MoxR-like ATPases General function prediction only - - - 0.00000000000000000001129 104.0
HKD2_k127_4315617_8 - - - - 0.000000000000005105 81.0
HKD2_k127_4315617_9 TIGRFAM Molybdenum-pterin binding - - - 0.0000000001062 64.0
HKD2_k127_4536027_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.263e-194 618.0
HKD2_k127_4536027_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000003153 93.0
HKD2_k127_4536027_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0004308 46.0
HKD2_k127_4675561_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 336.0
HKD2_k127_4675561_1 - - - - 0.000000000000000000000000000000000000000000000000000001322 215.0
HKD2_k127_4703573_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 591.0
HKD2_k127_4703573_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 417.0
HKD2_k127_4703573_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 408.0
HKD2_k127_4703573_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000001528 116.0
HKD2_k127_4708394_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.00000000000000000000000000000000000000000000000000000000000003926 223.0
HKD2_k127_4708394_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000003457 181.0
HKD2_k127_4708394_2 - - - - 0.00000000000000000000000000001332 126.0
HKD2_k127_4708394_3 - - - - 0.000000002604 67.0
HKD2_k127_4734204_0 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000003268 174.0
HKD2_k127_4734204_1 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.00000000000000000000000000000000000000000004137 170.0
HKD2_k127_4734204_2 Hep Hag repeat protein - - - 0.00000000000005462 83.0
HKD2_k127_4734204_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - 0.0000009923 55.0
HKD2_k127_477049_0 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 348.0
HKD2_k127_477049_1 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768 - 2.7.1.202 0.000000000000000000000000001062 130.0
HKD2_k127_481788_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1167.0
HKD2_k127_481788_1 PFAM Rhomboid family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001078 247.0
HKD2_k127_481788_2 peroxiredoxin activity - - - 0.0000000000000000000000002181 109.0
HKD2_k127_491326_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 450.0
HKD2_k127_491326_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 345.0
HKD2_k127_491326_10 Pilus assembly protein, PilP K02665 - - 0.0000000000000006179 86.0
HKD2_k127_491326_11 PFAM Fimbrial assembly K02663 - - 0.000000000000004977 82.0
HKD2_k127_491326_12 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.0001514 48.0
HKD2_k127_491326_2 PFAM type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 314.0
HKD2_k127_491326_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000003773 219.0
HKD2_k127_491326_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000368 191.0
HKD2_k127_491326_5 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000006213 138.0
HKD2_k127_491326_6 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000002164 131.0
HKD2_k127_491326_7 OmpA family K02557 - - 0.00000000000000000000000001939 125.0
HKD2_k127_491326_8 - - - - 0.00000000000000000007197 104.0
HKD2_k127_491326_9 PFAM helix-turn-helix domain protein - - - 0.0000000000000001211 81.0
HKD2_k127_4914347_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 428.0
HKD2_k127_4914347_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 371.0
HKD2_k127_4914347_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005931 278.0
HKD2_k127_4914347_3 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001001 252.0
HKD2_k127_4914347_4 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006612 240.0
HKD2_k127_5091557_0 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 422.0
HKD2_k127_5091557_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 263.0
HKD2_k127_5091557_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000005789 127.0
HKD2_k127_5091557_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000000433 75.0
HKD2_k127_509828_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 575.0
HKD2_k127_509828_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 477.0
HKD2_k127_509828_2 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000009834 184.0
HKD2_k127_5107090_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000004351 182.0
HKD2_k127_5107090_1 Thioredoxin - - - 0.000000000000000000000000001431 116.0
HKD2_k127_5107090_2 40-residue YVTN family beta-propeller repeat - - - 0.00000005049 61.0
HKD2_k127_5107090_3 Glycine-zipper domain - - - 0.0000001234 56.0
HKD2_k127_5121805_0 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 0.0 1040.0
HKD2_k127_5121805_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 4.734e-218 694.0
HKD2_k127_5121805_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.251e-207 668.0
HKD2_k127_5121805_3 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000002526 226.0
HKD2_k127_5121805_4 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000000000000000000003059 213.0
HKD2_k127_5121805_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000002507 163.0
HKD2_k127_5121805_6 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000000000000000000000000000000000007562 161.0
HKD2_k127_5121805_7 PFAM 4Fe-4S binding domain - - - 0.00000000000000000000000000000000008521 139.0
HKD2_k127_5121805_8 Iron hydrogenase small subunit - - - 0.0000001449 55.0
HKD2_k127_5148531_0 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 368.0
HKD2_k127_5148531_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 302.0
HKD2_k127_5148531_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
HKD2_k127_5148531_3 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001895 293.0
HKD2_k127_5148531_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000001049 175.0
HKD2_k127_5148531_5 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000002591 107.0
HKD2_k127_5148531_6 Ftsk_gamma K03466 - - 0.0000000000001812 70.0
HKD2_k127_5184927_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 1.919e-222 706.0
HKD2_k127_5184927_1 aminotransferase, class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 477.0
HKD2_k127_5184927_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000007535 113.0
HKD2_k127_5184927_3 NHL repeat - - - 0.00000000002394 77.0
HKD2_k127_5187177_0 PFAM asparagine synthase K01953 - 6.3.5.4 3.443e-201 645.0
HKD2_k127_5187177_1 Glycosyl transferases group 1 - - - 0.0000002273 58.0
HKD2_k127_5202104_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K18847 - 2.1.2.1,2.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 606.0
HKD2_k127_5202104_1 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001393 266.0
HKD2_k127_5202104_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000003174 70.0
HKD2_k127_5244819_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K12142,K15830 GO:0003674,GO:0005488,GO:0016151,GO:0043167,GO:0043169,GO:0046872,GO:0046914 1.6.5.3 2.945e-255 797.0
HKD2_k127_5244819_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 2.977e-233 739.0
HKD2_k127_5244819_2 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 561.0
HKD2_k127_5244819_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 473.0
HKD2_k127_5244819_4 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 366.0
HKD2_k127_5244819_5 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 361.0
HKD2_k127_5244819_6 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 308.0
HKD2_k127_5244819_7 Dihydrodipicolinate synthetase family - - - 0.000000000000000000000000000000000000000000000000000004333 203.0
HKD2_k127_5244819_8 spore germination K00442,K08315 - 3.4.23.51 0.00000000000000000000000000000000009286 139.0
HKD2_k127_5244819_9 4Fe-4S dicluster domain - - - 0.000005754 49.0
HKD2_k127_5248812_0 PFAM ABC transporter K06158 - - 6.323e-241 758.0
HKD2_k127_5248812_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 427.0
HKD2_k127_5248812_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 316.0
HKD2_k127_5248812_3 Belongs to the SfsA family K06206 - - 0.000000000000000000000000000000006554 129.0
HKD2_k127_5248812_4 - - - - 0.000000000002403 72.0
HKD2_k127_5249643_0 NADH dehydrogenase K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 505.0
HKD2_k127_5249643_1 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 320.0
HKD2_k127_5249643_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000007483 222.0
HKD2_k127_5249643_3 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.000000000000000000000000000000001815 139.0
HKD2_k127_5249643_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000004425 102.0
HKD2_k127_5249643_5 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000002666 90.0
HKD2_k127_5249643_6 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000004266 70.0
HKD2_k127_5249643_7 Domain of unknown function (DUF362) - - - 0.0000005192 61.0
HKD2_k127_5265367_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 481.0
HKD2_k127_5265367_1 Class III cytochrome C family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 338.0
HKD2_k127_5265367_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 312.0
HKD2_k127_5265367_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000001235 123.0
HKD2_k127_5265367_4 4Fe-4S dicluster domain - - - 0.00000002794 56.0
HKD2_k127_5270419_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 309.0
HKD2_k127_5270419_1 4Fe-4S dicluster domain K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 309.0
HKD2_k127_5270419_2 Biotin-protein ligase, N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 303.0
HKD2_k127_5270419_3 PFAM Nitrate reductase gamma subunit - - - 0.00000001101 64.0
HKD2_k127_5282232_0 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003839 283.0
HKD2_k127_5282232_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000003506 239.0
HKD2_k127_5282232_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000008995 203.0
HKD2_k127_5282232_3 O-acyltransferase activity K00661,K21379 - 2.3.1.209,2.3.1.79 0.000000000000000000006787 98.0
HKD2_k127_5282232_4 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.00000004669 66.0
HKD2_k127_5282232_5 ubiE/COQ5 methyltransferase family - - - 0.00009637 49.0
HKD2_k127_5283335_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 540.0
HKD2_k127_5283335_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000001426 167.0
HKD2_k127_5324514_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.0 1031.0
HKD2_k127_5324514_1 Carbon starvation protein K06200 - - 1.194e-243 767.0
HKD2_k127_5324514_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 307.0
HKD2_k127_5324514_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000003212 199.0
HKD2_k127_5324514_4 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000007973 202.0
HKD2_k127_5324514_5 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000007324 158.0
HKD2_k127_5324514_6 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 0.000000000000004266 77.0
HKD2_k127_5341028_0 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 3.984e-197 626.0
HKD2_k127_5341028_1 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 601.0
HKD2_k127_5341028_10 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000000000000000000000000000000000000000001522 203.0
HKD2_k127_5341028_11 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000001506 197.0
HKD2_k127_5341028_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000005656 175.0
HKD2_k127_5341028_13 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000005932 169.0
HKD2_k127_5341028_14 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000009761 112.0
HKD2_k127_5341028_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000004381 100.0
HKD2_k127_5341028_2 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 411.0
HKD2_k127_5341028_3 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 326.0
HKD2_k127_5341028_4 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008283 263.0
HKD2_k127_5341028_5 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000356 241.0
HKD2_k127_5341028_6 COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000007482 240.0
HKD2_k127_5341028_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000645 223.0
HKD2_k127_5341028_8 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000007701 218.0
HKD2_k127_5341028_9 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000001129 211.0
HKD2_k127_5346858_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 537.0
HKD2_k127_5346858_1 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 374.0
HKD2_k127_5346858_10 DRTGG domain - - - 0.00000000000000000000000000000002905 130.0
HKD2_k127_5346858_11 DRTGG domain - - - 0.0000000000000000000000000000001436 128.0
HKD2_k127_5346858_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000008548 107.0
HKD2_k127_5346858_13 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000007456 57.0
HKD2_k127_5346858_2 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 366.0
HKD2_k127_5346858_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001148 252.0
HKD2_k127_5346858_4 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000002733 231.0
HKD2_k127_5346858_5 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000007271 198.0
HKD2_k127_5346858_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001354 183.0
HKD2_k127_5346858_7 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000001151 163.0
HKD2_k127_5346858_8 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000001516 150.0
HKD2_k127_5346858_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000003781 133.0
HKD2_k127_5359729_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 420.0
HKD2_k127_5359729_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 407.0
HKD2_k127_5359729_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 344.0
HKD2_k127_5359729_3 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 309.0
HKD2_k127_5359729_4 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010468,GO:0010563,GO:0010605,GO:0010629,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0060255,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000001688 184.0
HKD2_k127_5359729_5 heparin binding K04659,K16857 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.000000000000000000001483 104.0
HKD2_k127_5359729_6 phosphate-selective porin K07221 - - 0.00001442 49.0
HKD2_k127_5374193_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 8.712e-291 902.0
HKD2_k127_5374193_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 1.481e-195 636.0
HKD2_k127_5374193_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000335 221.0
HKD2_k127_5374193_3 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000000005605 157.0
HKD2_k127_5374193_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.000000000000000000000439 97.0
HKD2_k127_5374193_5 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000005216 78.0
HKD2_k127_5391747_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 490.0
HKD2_k127_5391747_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 374.0
HKD2_k127_5391747_2 FtsZ-dependent cytokinesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006831 289.0
HKD2_k127_5391747_3 Belongs to the Fur family K09825 - - 0.00000000000000000000000000000000002057 140.0
HKD2_k127_5391747_4 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000001284 117.0
HKD2_k127_5391747_5 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000000001092 94.0
HKD2_k127_5391747_6 Rubrerythrin - - - 0.0000004233 61.0
HKD2_k127_543486_0 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 408.0
HKD2_k127_543486_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 397.0
HKD2_k127_543486_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 379.0
HKD2_k127_543486_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 372.0
HKD2_k127_543486_4 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 354.0
HKD2_k127_543486_5 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 317.0
HKD2_k127_543486_6 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000006378 266.0
HKD2_k127_543486_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000002998 121.0
HKD2_k127_5443736_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.647e-205 653.0
HKD2_k127_5443736_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 569.0
HKD2_k127_5443736_10 C4-type zinc ribbon domain K07164 - - 0.000000001686 65.0
HKD2_k127_5443736_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 364.0
HKD2_k127_5443736_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000009964 261.0
HKD2_k127_5443736_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001055 250.0
HKD2_k127_5443736_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000001185 194.0
HKD2_k127_5443736_6 YacP-like NYN domain K06962 - - 0.0000000000000000000000000000009832 128.0
HKD2_k127_5443736_7 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000004258 97.0
HKD2_k127_5443736_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000007112 97.0
HKD2_k127_5443736_9 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000001148 92.0
HKD2_k127_5445699_0 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 420.0
HKD2_k127_5445699_1 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 403.0
HKD2_k127_5445699_2 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003162 277.0
HKD2_k127_5445699_3 HypF finger K04656 - - 0.00000000000000000005969 91.0
HKD2_k127_5445699_4 HupF/HypC family K04653 - - 0.0000000000000003057 80.0
HKD2_k127_5445699_5 ABC-2 type transporter - - - 0.0001034 53.0
HKD2_k127_546614_0 Domain of unknown function (DUF1998) K06877 - - 3.729e-297 929.0
HKD2_k127_546614_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000001293 210.0
HKD2_k127_546614_2 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000785 159.0
HKD2_k127_546614_3 peptidyl-tyrosine sulfation - - - 0.000002731 53.0
HKD2_k127_5503512_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.317e-248 778.0
HKD2_k127_5503512_1 PAS domain K13598 - 2.7.13.3 2.373e-242 770.0
HKD2_k127_5503512_2 phosphorelay signal transduction system K02535,K13599,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 528.0
HKD2_k127_5503512_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 413.0
HKD2_k127_5503512_4 Cell Wall K01448 - 3.5.1.28 0.000000000000000000000007097 115.0
HKD2_k127_5503512_5 Bacterial DNA-binding protein K03530 - - 0.0000001256 55.0
HKD2_k127_5503512_6 S-layer homology domain - - - 0.0001351 54.0
HKD2_k127_5509136_0 Class II vitamin B12-dependent ribonucleotide reductase K00525 - 1.17.4.1 0.0 1494.0
HKD2_k127_5509136_1 PFAM Glycoside hydrolase 15-related - - - 1.611e-299 945.0
HKD2_k127_5509136_2 ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 592.0
HKD2_k127_5525677_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 5.594e-208 663.0
HKD2_k127_5569760_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 483.0
HKD2_k127_5569760_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000004065 87.0
HKD2_k127_5569760_3 - - - - 0.00003742 53.0
HKD2_k127_5611391_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 6.933e-225 726.0
HKD2_k127_5611391_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 597.0
HKD2_k127_5611391_2 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 377.0
HKD2_k127_5658132_0 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 456.0
HKD2_k127_5658132_1 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000006206 213.0
HKD2_k127_5658132_2 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000004634 136.0
HKD2_k127_5658132_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000009672 106.0
HKD2_k127_5658132_4 Protein of unknown function (DUF1329) - - - 0.00000000000144 79.0
HKD2_k127_5658132_5 Sh3 type 3 domain protein - - - 0.0000001726 64.0
HKD2_k127_5712224_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 454.0
HKD2_k127_5712224_1 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
HKD2_k127_5712224_2 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 301.0
HKD2_k127_5712224_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000001972 184.0
HKD2_k127_5712224_4 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000001273 176.0
HKD2_k127_5712224_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000006361 145.0
HKD2_k127_5712224_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000001923 126.0
HKD2_k127_5712224_7 Amidohydrolase K07045 - - 0.0000000000000000000601 101.0
HKD2_k127_5712224_8 FAD linked oxidase K18930 - - 0.0000000000000001595 93.0
HKD2_k127_5712224_9 Coproporphyrinogen III oxidase K00228 - 1.3.3.3 0.0000000000001964 79.0
HKD2_k127_5729489_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 5.273e-224 698.0
HKD2_k127_5729489_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 513.0
HKD2_k127_5729489_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 453.0
HKD2_k127_5729489_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 441.0
HKD2_k127_5729489_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 369.0
HKD2_k127_5729489_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 317.0
HKD2_k127_5729489_6 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003087 254.0
HKD2_k127_5729489_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000005066 220.0
HKD2_k127_5729489_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000008395 173.0
HKD2_k127_5729489_9 Binds the 23S rRNA K02909 - - 0.000000000000000000000000007338 111.0
HKD2_k127_574891_0 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 457.0
HKD2_k127_574891_1 Amine oxidase, flavin-containing - - - 0.00000000000000000000000000000000000000000000000000000036 214.0
HKD2_k127_574891_2 - - - - 0.00000000000000000000000000000000000000000000001979 184.0
HKD2_k127_574891_3 metallopeptidase activity - - - 0.00002132 57.0
HKD2_k127_5750587_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.624e-208 658.0
HKD2_k127_5750587_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 457.0
HKD2_k127_5750587_10 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000006532 221.0
HKD2_k127_5750587_11 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000007498 214.0
HKD2_k127_5750587_12 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000114 209.0
HKD2_k127_5750587_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006521 200.0
HKD2_k127_5750587_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000009056 200.0
HKD2_k127_5750587_15 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000008251 190.0
HKD2_k127_5750587_16 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001781 181.0
HKD2_k127_5750587_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000002516 173.0
HKD2_k127_5750587_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000007068 163.0
HKD2_k127_5750587_19 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000005297 158.0
HKD2_k127_5750587_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 422.0
HKD2_k127_5750587_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000002046 154.0
HKD2_k127_5750587_21 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000003564 152.0
HKD2_k127_5750587_22 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000004597 145.0
HKD2_k127_5750587_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000009554 142.0
HKD2_k127_5750587_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000001123 131.0
HKD2_k127_5750587_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002969 114.0
HKD2_k127_5750587_26 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000005962 110.0
HKD2_k127_5750587_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000002622 102.0
HKD2_k127_5750587_28 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000001028 74.0
HKD2_k127_5750587_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003181 67.0
HKD2_k127_5750587_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 372.0
HKD2_k127_5750587_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 297.0
HKD2_k127_5750587_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 291.0
HKD2_k127_5750587_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 285.0
HKD2_k127_5750587_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 286.0
HKD2_k127_5750587_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 238.0
HKD2_k127_5750587_9 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000008382 229.0
HKD2_k127_5777809_0 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 377.0
HKD2_k127_5777809_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 379.0
HKD2_k127_5777809_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000458 180.0
HKD2_k127_5777809_3 PFAM plasmid stabilization system K06218 - - 0.0000000000000000000000000000000003661 132.0
HKD2_k127_5777809_4 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000002781 136.0
HKD2_k127_5777809_5 MarR family transcriptional regulator - - - 0.00000000000000000007318 94.0
HKD2_k127_5777809_6 - - - - 0.000000000000000008595 85.0
HKD2_k127_5778909_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K00355,K05587,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.446e-280 871.0
HKD2_k127_5778909_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 411.0
HKD2_k127_5778909_2 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 398.0
HKD2_k127_5778909_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004845 284.0
HKD2_k127_5778909_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000107 242.0
HKD2_k127_5778909_5 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000004907 193.0
HKD2_k127_5778909_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001753 187.0
HKD2_k127_5778909_7 TIGRFAM diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.65 0.00000000000000000000008735 102.0
HKD2_k127_5806414_0 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000000000006788 153.0
HKD2_k127_5806414_1 Cupin domain - - - 0.000000000000000000000000000000005649 135.0
HKD2_k127_5806414_2 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000004994 127.0
HKD2_k127_5828652_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 310.0
HKD2_k127_5828652_1 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 292.0
HKD2_k127_5828652_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000003073 251.0
HKD2_k127_5837835_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 554.0
HKD2_k127_5837835_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 355.0
HKD2_k127_5851506_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.306e-243 766.0
HKD2_k127_5851506_1 PFAM Phosphate-starvation-inducible - - - 0.0000000000000000000000000000000000000000000002632 170.0
HKD2_k127_588500_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 375.0
HKD2_k127_588500_1 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000006896 173.0
HKD2_k127_588500_2 PAC2 family - - - 0.0000000000000000000000000000001623 134.0
HKD2_k127_588500_3 peroxiredoxin activity - - - 0.0000000000000000007607 100.0
HKD2_k127_5887004_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 543.0
HKD2_k127_5887004_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004653 271.0
HKD2_k127_5887004_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000001436 128.0
HKD2_k127_5887004_3 Belongs to the Fur family K09825,K22297 - - 0.0000000000000000000000000000001543 129.0
HKD2_k127_5887004_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000002065 65.0
HKD2_k127_595644_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 387.0
HKD2_k127_595644_1 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000003529 207.0
HKD2_k127_595644_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000006451 204.0
HKD2_k127_595644_3 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000002927 185.0
HKD2_k127_595644_4 phosphorelay signal transduction system - - - 0.0000000000000652 86.0
HKD2_k127_5972398_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.442e-299 930.0
HKD2_k127_5972398_1 PFAM major facilitator superfamily MFS_1 K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005907 239.0
HKD2_k127_5972398_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000001068 170.0
HKD2_k127_5972398_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000001737 79.0
HKD2_k127_6025079_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 - 2.4.1.321 0.0 1052.0
HKD2_k127_6025079_1 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 557.0
HKD2_k127_6025079_2 Belongs to the precorrin methyltransferase family K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003992 281.0
HKD2_k127_6095098_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 2.045e-298 923.0
HKD2_k127_6095098_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 315.0
HKD2_k127_6095098_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 287.0
HKD2_k127_6095098_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
HKD2_k127_6112651_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 301.0
HKD2_k127_6112651_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002386 262.0
HKD2_k127_6112651_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000002354 227.0
HKD2_k127_6112651_3 PFAM ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000002229 210.0
HKD2_k127_6112651_4 ATP-binding region ATPase domain protein, histidine kinase dimerization and phosphoacceptor region - - - 0.000001948 51.0
HKD2_k127_6171272_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 513.0
HKD2_k127_6171272_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 401.0
HKD2_k127_6171272_2 Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L- methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 0.00000000000000000000000000000165 120.0
HKD2_k127_6171272_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000004563 108.0
HKD2_k127_6171272_4 Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L- methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by K22466 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.23 0.000000000006335 66.0
HKD2_k127_617961_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 452.0
HKD2_k127_617961_1 Glycosyltransferase Family 4 K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000074 274.0
HKD2_k127_617961_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000002346 147.0
HKD2_k127_617961_3 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.00000000000000000000000000002662 136.0
HKD2_k127_6268896_0 FAD binding domain - - - 0.000000000000000000000000000000000000001727 163.0
HKD2_k127_6268896_1 - - - - 0.0000000000000000000000000000000001129 147.0
HKD2_k127_6268896_2 FAD binding domain - - - 0.0000000000000000001012 90.0
HKD2_k127_6268896_3 Ferredoxin-dependent bilin reductase K08101 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0010019,GO:0016491,GO:0016627,GO:0016636,GO:0023052,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050619,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007 1.3.7.4 0.0000000007604 69.0
HKD2_k127_6268896_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00003126 50.0
HKD2_k127_6268896_5 Phytochromobilin ferredoxin oxidoreductase K08101 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0010019,GO:0016491,GO:0016627,GO:0016636,GO:0023052,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0050619,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007 1.3.7.4 0.0002986 51.0
HKD2_k127_6375165_0 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 374.0
HKD2_k127_6375165_1 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 312.0
HKD2_k127_6375165_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 297.0
HKD2_k127_6375165_3 AIR synthase related protein, C-terminal domain K00946 - 2.7.4.16 0.00000000000000000000000000000000000005959 148.0
HKD2_k127_6392555_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 446.0
HKD2_k127_6392555_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007109 255.0
HKD2_k127_6392555_2 - - - - 0.0000008248 61.0
HKD2_k127_6421365_0 Amino acid kinase family K00947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 463.0
HKD2_k127_6421365_1 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 307.0
HKD2_k127_6421365_2 - - - - 0.00000000000000000003046 94.0
HKD2_k127_6421365_3 PFAM Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain K07005 - - 0.000006916 54.0
HKD2_k127_6435761_0 Heat shock 70 kDa protein K04043 - - 3.852e-313 968.0
HKD2_k127_6435761_1 Belongs to the ClpA ClpB family K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 503.0
HKD2_k127_6435761_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000005776 167.0
HKD2_k127_64542_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 445.0
HKD2_k127_64542_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 388.0
HKD2_k127_64542_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 327.0
HKD2_k127_64542_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005618 279.0
HKD2_k127_64542_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000001252 164.0
HKD2_k127_64542_5 - - - - 0.0000000000000000000000000000000000000000002638 173.0
HKD2_k127_64542_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000003301 74.0
HKD2_k127_6482296_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 503.0
HKD2_k127_6482296_1 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000001339 254.0
HKD2_k127_6482296_2 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000001889 153.0
HKD2_k127_6482296_3 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000001984 57.0
HKD2_k127_6489389_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 587.0
HKD2_k127_6489389_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 499.0
HKD2_k127_6489389_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 400.0
HKD2_k127_6489389_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000005871 231.0
HKD2_k127_6489389_4 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000009558 230.0
HKD2_k127_6489389_5 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000004103 218.0
HKD2_k127_6489389_6 ATP cone domain K07738 - - 0.000000000000000000000000000000000000000000000000000000000006407 212.0
HKD2_k127_6489389_7 TIGRFAM iron-sulfur cluster binding protein K18979 - 1.17.99.6 0.0000000000000000000000000000000000000006336 157.0
HKD2_k127_6489389_8 NusB family K03625 - - 0.000000000000000000000000000000000000002665 151.0
HKD2_k127_6489389_9 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000001263 154.0
HKD2_k127_6491610_0 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 377.0
HKD2_k127_6491610_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000398 217.0
HKD2_k127_6491610_2 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000002333 208.0
HKD2_k127_6491610_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000005455 184.0
HKD2_k127_6491610_4 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000003085 178.0
HKD2_k127_6491610_5 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000004688 100.0
HKD2_k127_6491610_6 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0002999 44.0
HKD2_k127_6494287_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.724e-213 692.0
HKD2_k127_6494287_1 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 606.0
HKD2_k127_6494287_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 584.0
HKD2_k127_6494287_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 479.0
HKD2_k127_6494287_4 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 411.0
HKD2_k127_6494287_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 346.0
HKD2_k127_6494287_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 316.0
HKD2_k127_6494287_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006287 291.0
HKD2_k127_6494287_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007414 268.0
HKD2_k127_6494287_9 Outer membrane protein (OmpH-like) K06142 - - 0.0001109 47.0
HKD2_k127_6499124_0 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 404.0
HKD2_k127_6499124_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001522 282.0
HKD2_k127_6499124_2 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000003319 217.0
HKD2_k127_6499124_3 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.0000000000001242 78.0
HKD2_k127_6499124_4 cAMP biosynthetic process - - - 0.000004923 53.0
HKD2_k127_6517118_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 428.0
HKD2_k127_6517118_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 269.0
HKD2_k127_6517118_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000002952 194.0
HKD2_k127_6517118_3 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000004561 185.0
HKD2_k127_6517118_4 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000005701 153.0
HKD2_k127_6517118_5 gas vesicle protein - - - 0.00000000401 62.0
HKD2_k127_6517118_6 L-asparaginase II - - - 0.000008774 50.0
HKD2_k127_6522925_0 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 434.0
HKD2_k127_6522925_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000002877 199.0
HKD2_k127_6522925_2 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000003296 145.0
HKD2_k127_6522925_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000004069 107.0
HKD2_k127_6523465_0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 2.911e-200 627.0
HKD2_k127_6523465_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 544.0
HKD2_k127_6523465_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 394.0
HKD2_k127_6523465_3 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 320.0
HKD2_k127_6523465_4 Domain of unknown function (DUF4410) - - - 0.00000000000000000001684 100.0
HKD2_k127_6524802_0 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 312.0
HKD2_k127_6524802_1 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000007612 170.0
HKD2_k127_6524802_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000001307 121.0
HKD2_k127_6524802_3 Ribbon-helix-helix domain - - - 0.0000005909 54.0
HKD2_k127_6524802_4 Predicted metal-binding protein (DUF2284) - - - 0.00001745 55.0
HKD2_k127_6536654_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 468.0
HKD2_k127_6536654_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 345.0
HKD2_k127_6536654_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 315.0
HKD2_k127_6536654_3 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000005329 226.0
HKD2_k127_6536654_4 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000001076 103.0
HKD2_k127_6548584_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 528.0
HKD2_k127_6548584_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005002 281.0
HKD2_k127_6548584_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002901 263.0
HKD2_k127_6548584_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
HKD2_k127_6548584_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000181 155.0
HKD2_k127_6548584_5 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000000003483 123.0
HKD2_k127_6548584_6 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000006976 121.0
HKD2_k127_6548584_7 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000006344 109.0
HKD2_k127_6554631_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 516.0
HKD2_k127_6554631_1 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000002605 213.0
HKD2_k127_6554631_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000001196 207.0
HKD2_k127_6554631_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000001097 165.0
HKD2_k127_6554631_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000009078 107.0
HKD2_k127_6554631_5 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000002205 106.0
HKD2_k127_6554631_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000001407 106.0
HKD2_k127_6554631_7 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000009274 100.0
HKD2_k127_6554631_8 4Fe-4S dicluster domain - - - 0.0000271 55.0
HKD2_k127_6554631_9 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.00005266 52.0
HKD2_k127_6582243_0 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 357.0
HKD2_k127_6582243_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000001854 252.0
HKD2_k127_6582243_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000003062 126.0
HKD2_k127_6611236_0 Sporulation initiation inhibitor protein Soj K03496 - - 0.000000000000000000000000000000000000000000000000000705 196.0
HKD2_k127_6611236_1 Dodecin K09165 - - 0.0000000000000000000000009174 104.0
HKD2_k127_6675681_0 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000004457 218.0
HKD2_k127_6675681_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000007183 153.0
HKD2_k127_6684928_0 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 546.0
HKD2_k127_6684928_1 Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 524.0
HKD2_k127_6684928_10 Cation efflux family K16264 - - 0.0000000003117 68.0
HKD2_k127_6684928_2 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 451.0
HKD2_k127_6684928_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 306.0
HKD2_k127_6684928_4 Formate dehydrogenase alpha subunit K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 299.0
HKD2_k127_6684928_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000203 230.0
HKD2_k127_6684928_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000003133 177.0
HKD2_k127_6684928_7 PFAM Cyclic nucleotide-binding domain - - - 0.00000000000000000000000000006326 122.0
HKD2_k127_6684928_8 PFAM Rhodanese domain protein - - - 0.0000000000000006027 85.0
HKD2_k127_6684928_9 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000002464 77.0
HKD2_k127_6795373_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1562.0
HKD2_k127_6795373_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 480.0
HKD2_k127_6795373_2 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 436.0
HKD2_k127_6843326_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 5.838e-228 721.0
HKD2_k127_6843326_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 607.0
HKD2_k127_6843326_2 4 iron, 4 sulfur cluster binding K03522,K13795,K15511 - 1.14.13.208 0.00000000000000000000000000000001925 132.0
HKD2_k127_6891109_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 493.0
HKD2_k127_6891109_1 - - - - 0.000000000000000000000000000004446 122.0
HKD2_k127_6891109_2 Major Facilitator K08153 - - 0.000000000000000000000000004573 115.0
HKD2_k127_6891109_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000001185 69.0
HKD2_k127_6900224_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 563.0
HKD2_k127_6900224_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 296.0
HKD2_k127_6900224_2 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 293.0
HKD2_k127_6900224_3 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005315 294.0
HKD2_k127_6900224_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000752 133.0
HKD2_k127_6941913_0 Fibrobacter succinogenes major domain (Fib_succ_major) - - - 0.0000000000000000000000000000000000001071 151.0
HKD2_k127_6941913_1 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000006414 85.0
HKD2_k127_6941913_2 Protein of unknown function (DUF1566) - - - 0.000001093 61.0
HKD2_k127_6941913_3 Subtilase family K13274 - - 0.0004101 50.0
HKD2_k127_7001232_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.124e-236 737.0
HKD2_k127_7001232_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00972 - 2.7.7.23,2.7.7.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 536.0
HKD2_k127_7007376_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 310.0
HKD2_k127_7007376_1 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000001089 166.0
HKD2_k127_7042915_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.499e-260 816.0
HKD2_k127_7042915_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005103 276.0
HKD2_k127_7042915_2 Sporulation and spore germination - - - 0.000000000000000000004126 101.0
HKD2_k127_7068040_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 8.945e-259 811.0
HKD2_k127_7068040_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000002196 71.0
HKD2_k127_7077475_0 TIGRFAM methylmalonyl-CoA mutase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 602.0
HKD2_k127_7077475_1 cobalamin binding - - - 0.000000000000000000000000000000000000008263 149.0
HKD2_k127_7077475_2 diacylglycerol O-acyltransferase - - - 0.00001802 57.0
HKD2_k127_7136598_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 507.0
HKD2_k127_7136598_1 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 406.0
HKD2_k127_7136598_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004444 256.0
HKD2_k127_7136598_3 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000003279 236.0
HKD2_k127_7136598_4 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000000002067 156.0
HKD2_k127_7136598_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000004524 78.0
HKD2_k127_7136598_6 Domain of unknown function (DUF362) K07138 - - 0.00000000000005328 73.0
HKD2_k127_7136598_7 general stress protein - - - 0.0000000001028 68.0
HKD2_k127_722714_0 SMART Phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 537.0
HKD2_k127_722714_1 nitric oxide reductase activity - - - 0.0000000000000000000000000000000000000000000001586 172.0
HKD2_k127_722714_2 HemY protein - - - 0.0000000000000000000000001591 117.0
HKD2_k127_7303704_0 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 564.0
HKD2_k127_7303704_1 signal transduction Histidine kinase K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 362.0
HKD2_k127_7303704_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000004556 142.0
HKD2_k127_7303704_3 pyridoxamine 5'-phosphate K07005 - - 0.000000000005812 73.0
HKD2_k127_7331774_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 297.0
HKD2_k127_7331774_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000004863 268.0
HKD2_k127_7331774_2 Aminotransferase class-III K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000192 220.0
HKD2_k127_7331774_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000001653 153.0
HKD2_k127_7331774_4 Phosphopantetheine attachment site - - - 0.0000000000000000000000001001 111.0
HKD2_k127_7331774_5 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.00000000000000000000000387 105.0
HKD2_k127_7336698_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 394.0
HKD2_k127_7336698_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 380.0
HKD2_k127_7367742_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.064e-197 639.0
HKD2_k127_7528775_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1262.0
HKD2_k127_7528775_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002823 293.0
HKD2_k127_7528775_2 Outer membrane efflux protein K15725 - - 0.0000001186 53.0
HKD2_k127_75819_0 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001237 268.0
HKD2_k127_75819_1 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002212 254.0
HKD2_k127_7586032_0 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 295.0
HKD2_k127_7586032_1 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000929 222.0
HKD2_k127_7586032_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000001269 221.0
HKD2_k127_7586032_3 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000002027 166.0
HKD2_k127_7586032_4 4Fe-4S binding domain - - - 0.000005453 57.0
HKD2_k127_7593542_0 PFAM metal-dependent phosphohydrolase, HD sub domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000000001079 231.0
HKD2_k127_7593542_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000006164 162.0
HKD2_k127_7666366_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 322.0
HKD2_k127_7666366_1 Domain of unknown function (DUF4956) - - - 0.0000000000000000000000000000000000000000001793 167.0
HKD2_k127_7666366_2 VTC domain - - - 0.0000000000000000000000017 113.0
HKD2_k127_7666366_3 Domain of unknown function (DUF4956) - - - 0.0000005522 59.0
HKD2_k127_7666366_4 Spore coat protein CotH K06330 - - 0.00001291 58.0
HKD2_k127_7670761_0 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000002511 183.0
HKD2_k127_7670761_1 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.000000000000000000000000000000000000000001084 168.0
HKD2_k127_7670761_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000004239 140.0
HKD2_k127_7670761_3 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.00000000000000000000003926 101.0
HKD2_k127_7694893_0 Nad-dependent epimerase dehydratase K01709,K01710 - 4.2.1.45,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 415.0
HKD2_k127_7694893_1 TIGRFAM Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 357.0
HKD2_k127_7694893_2 NAD-dependent epimerase dehydratase K01709,K01710 - 4.2.1.45,4.2.1.46 0.000000000000000000000000000000000000000000000000000000492 204.0
HKD2_k127_7694893_3 PFAM NHL repeat containing protein - - - 0.000000001112 67.0
HKD2_k127_7694925_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000001364 191.0
HKD2_k127_7694925_1 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000005829 177.0
HKD2_k127_7694925_2 AsmA-like C-terminal region - - - 0.000000000000002663 91.0
HKD2_k127_7694925_3 Domain of Unknown Function (DUF748) - - - 0.0000000000006234 72.0
HKD2_k127_7706719_0 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 461.0
HKD2_k127_7706719_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 344.0
HKD2_k127_7706719_2 HD domain - - - 0.000000000000000000000004287 107.0
HKD2_k127_7706719_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000005097 53.0
HKD2_k127_7713706_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 5.297e-195 617.0
HKD2_k127_7713706_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000001468 180.0
HKD2_k127_7713706_2 Thiamine-binding protein - - - 0.00000000000000004537 81.0
HKD2_k127_7728792_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 523.0
HKD2_k127_7728792_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004069 243.0
HKD2_k127_7728792_2 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000004126 149.0
HKD2_k127_7761383_0 PFAM magnesium chelatase ChlI subunit K07391 - - 5.001e-211 668.0
HKD2_k127_7761383_1 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 407.0
HKD2_k127_7761383_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000004591 194.0
HKD2_k127_7761383_3 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.000000000000000000000000000115 118.0
HKD2_k127_7761383_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000001631 65.0
HKD2_k127_7762802_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1179.0
HKD2_k127_7762802_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.23.36 0.000000000000054 76.0
HKD2_k127_7766656_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 586.0
HKD2_k127_7766656_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001303 259.0
HKD2_k127_7766656_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000007187 181.0
HKD2_k127_7811596_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.988e-222 703.0
HKD2_k127_7811596_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004992 286.0
HKD2_k127_7811596_2 Cytidylate kinase K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000003322 235.0
HKD2_k127_7811596_3 Glycogen recognition site of AMP-activated protein kinase - - - 0.00000000000000000000806 95.0
HKD2_k127_7811596_4 Thiamine-binding protein - - - 0.00000000000000000002201 93.0
HKD2_k127_7811596_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000002939 88.0
HKD2_k127_7814388_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 2.662e-242 764.0
HKD2_k127_7814388_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 585.0
HKD2_k127_7814388_2 Belongs to the HY2 family K05369 - 1.3.7.2 0.00000000000000000000000007949 116.0
HKD2_k127_7814388_3 - - - - 0.00000000003332 68.0
HKD2_k127_7824710_0 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 447.0
HKD2_k127_7824710_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 372.0
HKD2_k127_7824710_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 364.0
HKD2_k127_7824710_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 354.0
HKD2_k127_7824710_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000008276 210.0
HKD2_k127_7824710_5 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000001901 113.0
HKD2_k127_7900887_0 Threonine synthase N terminus K01733 - 4.2.3.1 1.381e-201 639.0
HKD2_k127_7900887_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 597.0
HKD2_k127_7900887_2 Adenylylsulphate kinase K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007002 276.0
HKD2_k127_7900887_3 - - - - 0.00000000000000000000000000000004586 127.0
HKD2_k127_7902011_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 5.605e-213 672.0
HKD2_k127_7902011_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000216 114.0
HKD2_k127_7916632_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000002552 202.0
HKD2_k127_7916632_1 FAD binding domain - - - 0.00000000001639 72.0
HKD2_k127_7916632_2 Helix-turn-helix domain - - - 0.000000000208 63.0
HKD2_k127_7916632_3 Thrombospondin type 3 repeat - - - 0.0000000002382 73.0
HKD2_k127_7916632_4 Helix-turn-helix domain - - - 0.00002283 49.0
HKD2_k127_7916632_5 Metallo-beta-lactamase superfamily - - - 0.0007318 42.0
HKD2_k127_7928744_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 3.161e-211 670.0
HKD2_k127_7928744_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000001847 157.0
HKD2_k127_7929697_0 Ribosomal protein L11 methyltransferase (PrmA) K15460 - 2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000006507 227.0
HKD2_k127_7929697_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000002173 141.0
HKD2_k127_7929697_2 Protein of unknown function (DUF721) - - - 0.0000000000000000002253 91.0
HKD2_k127_7929697_3 PilZ domain - - - 0.00002294 51.0
HKD2_k127_7929697_4 HEAT repeats - - - 0.0001721 50.0
HKD2_k127_79758_0 GTP-binding protein TypA K06207 - - 1.933e-231 733.0
HKD2_k127_79758_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 529.0
HKD2_k127_79758_2 CoA carboxylase activity K01615,K01965,K02160 - 4.1.1.70,6.4.1.3 0.000000000000000003193 88.0
HKD2_k127_79758_3 Lysin motif - - - 0.000000001987 64.0
HKD2_k127_79758_4 Hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.000945 43.0
HKD2_k127_7996390_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006521 238.0
HKD2_k127_7996390_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000002888 147.0
HKD2_k127_7996390_2 matrix metallopeptidase K07999 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004252,GO:0005488,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0009653,GO:0009887,GO:0009987,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022411,GO:0022603,GO:0022617,GO:0030163,GO:0030198,GO:0030574,GO:0032501,GO:0032502,GO:0032963,GO:0042475,GO:0042476,GO:0042481,GO:0042487,GO:0043062,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044421,GO:0046872,GO:0046914,GO:0048513,GO:0048646,GO:0048731,GO:0048856,GO:0050789,GO:0050793,GO:0051239,GO:0065007,GO:0070011,GO:0070167,GO:0070170,GO:0070173,GO:0071704,GO:0071840,GO:0097186,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:2000026,GO:2000027 - 0.0000001167 61.0
HKD2_k127_8038053_0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000001597 188.0
HKD2_k127_8038053_1 RDD family - - - 0.000000000000000000000000000000000001069 152.0
HKD2_k127_8038053_2 aspartic-type endopeptidase activity K06985 - - 0.00000000001647 76.0
HKD2_k127_8038053_3 Tetratricopeptide repeat - - - 0.000000004756 66.0
HKD2_k127_8072738_0 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 590.0
HKD2_k127_8072738_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 440.0
HKD2_k127_8072738_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 368.0
HKD2_k127_8072738_3 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 331.0
HKD2_k127_8072738_4 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002574 273.0
HKD2_k127_8072738_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000004692 211.0
HKD2_k127_8072738_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000003246 123.0
HKD2_k127_8072738_7 LysM domain - - - 0.000000000000000008765 94.0
HKD2_k127_8072738_8 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00000000000349 71.0
HKD2_k127_8114253_0 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 488.0
HKD2_k127_8114253_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 292.0
HKD2_k127_8114253_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000009625 256.0
HKD2_k127_8114253_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000008143 206.0
HKD2_k127_8114253_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000001146 169.0
HKD2_k127_8114253_5 Haemolytic - - - 0.0000000000000000000002137 103.0
HKD2_k127_8187117_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.639e-199 639.0
HKD2_k127_8187117_1 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000002631 235.0
HKD2_k127_8187117_2 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000002237 192.0
HKD2_k127_8187117_3 PFAM HD domain - - - 0.0000000000000000000000000000000000000000000000000000356 197.0
HKD2_k127_8187117_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000003793 190.0
HKD2_k127_8187117_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000001326 158.0
HKD2_k127_8187117_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000401 149.0
HKD2_k127_8187117_7 Mut7-C RNAse domain K09122 - - 0.000000000000000000000001953 108.0
HKD2_k127_8215628_0 aldo keto reductase K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 331.0
HKD2_k127_8215628_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000007032 242.0
HKD2_k127_8215628_2 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000007654 171.0
HKD2_k127_8215628_3 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000002872 170.0
HKD2_k127_8215628_4 peroxiredoxin activity - - - 0.000000000000000000000001549 110.0
HKD2_k127_8215628_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000008609 94.0
HKD2_k127_8215628_6 DNA binding domain, excisionase family - - - 0.000000000001239 70.0
HKD2_k127_8215628_7 HEAT repeats - - - 0.000000004874 66.0
HKD2_k127_8215628_8 Centromere protein F K11499 GO:0000075,GO:0000278,GO:0000775,GO:0000776,GO:0000777,GO:0000779,GO:0000793,GO:0000922,GO:0000940,GO:0001655,GO:0001822,GO:0003674,GO:0003682,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005694,GO:0005737,GO:0005819,GO:0005829,GO:0005856,GO:0005929,GO:0006355,GO:0006810,GO:0006996,GO:0007049,GO:0007059,GO:0007088,GO:0007093,GO:0007094,GO:0007275,GO:0007346,GO:0007399,GO:0007417,GO:0007420,GO:0008022,GO:0008104,GO:0008134,GO:0008150,GO:0008283,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010389,GO:0010468,GO:0010556,GO:0010558,GO:0010564,GO:0010605,GO:0010629,GO:0010639,GO:0010948,GO:0010965,GO:0012505,GO:0015031,GO:0015630,GO:0015833,GO:0016043,GO:0016202,GO:0016363,GO:0019219,GO:0019222,GO:0021591,GO:0022402,GO:0022607,GO:0030071,GO:0030496,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031577,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0034399,GO:0034508,GO:0034622,GO:0042221,GO:0042493,GO:0042802,GO:0042803,GO:0042886,GO:0042995,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044877,GO:0045184,GO:0045786,GO:0045839,GO:0045841,GO:0045892,GO:0045930,GO:0045934,GO:0046983,GO:0048471,GO:0048513,GO:0048519,GO:0048523,GO:0048634,GO:0048731,GO:0048856,GO:0050000,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051252,GO:0051253,GO:0051276,GO:0051303,GO:0051310,GO:0051382,GO:0051383,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0051726,GO:0051783,GO:0051784,GO:0051983,GO:0051985,GO:0060255,GO:0060322,GO:0065003,GO:0065004,GO:0065007,GO:0070013,GO:0070840,GO:0070925,GO:0071173,GO:0071174,GO:0071702,GO:0071705,GO:0071824,GO:0071840,GO:0072001,GO:0080090,GO:0097539,GO:0098687,GO:0098813,GO:0120025,GO:0120038,GO:1901861,GO:1901987,GO:1901988,GO:1901990,GO:1901991,GO:1902099,GO:1902100,GO:1902679,GO:1902749,GO:1903047,GO:1903506,GO:1903507,GO:1905818,GO:1905819,GO:2000026,GO:2000112,GO:2000113,GO:2000816,GO:2001141,GO:2001251 - 0.00003695 56.0
HKD2_k127_8234759_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.749e-236 756.0
HKD2_k127_8234759_1 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 464.0
HKD2_k127_8234759_2 tRNA pseudouridylate synthase B C-terminal domain K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000002945 231.0
HKD2_k127_8234759_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000009378 161.0
HKD2_k127_8234759_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000001066 122.0
HKD2_k127_8234759_5 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000001913 100.0
HKD2_k127_8234759_6 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000131 86.0
HKD2_k127_8234759_7 - - - - 0.000005384 49.0
HKD2_k127_8235185_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 300.0
HKD2_k127_8235185_1 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000002241 190.0
HKD2_k127_8235185_2 FAD binding domain - - - 0.00000000000000000000000000000000000008369 158.0
HKD2_k127_8259432_0 chlorophyllide reductase subunit Z K11335 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000002292 138.0
HKD2_k127_8259432_1 overlaps another CDS with the same product name K02586 - 1.18.6.1 0.0000000000004107 80.0
HKD2_k127_8259432_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000272 64.0
HKD2_k127_8265772_0 PFAM response regulator receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002615 263.0
HKD2_k127_8265772_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000012 164.0
HKD2_k127_8265772_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000003948 102.0
HKD2_k127_8311131_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 462.0
HKD2_k127_8311131_1 Radical SAM superfamily K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
HKD2_k127_8311131_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 304.0
HKD2_k127_8356819_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000002939 179.0
HKD2_k127_8356819_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001294 73.0
HKD2_k127_8365545_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 460.0
HKD2_k127_8365545_1 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 274.0
HKD2_k127_8365545_2 - - - - 0.0000008334 55.0
HKD2_k127_8365545_3 Cytochrome oxidase maturation protein - - - 0.0000924 48.0
HKD2_k127_8365545_4 - - - - 0.0001291 46.0
HKD2_k127_8399_0 Radical SAM N-terminal - - - 1.981e-273 850.0
HKD2_k127_8399_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
HKD2_k127_8531061_0 Transglycosylase SLT domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 490.0
HKD2_k127_8531061_1 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 299.0
HKD2_k127_8531061_2 sporulation initiation inhibitor protein Soj K03496 - - 0.00000000000000000000000000000000000000000000000000000005385 209.0
HKD2_k127_8531061_3 Belongs to the ParA family K04562 - - 0.000000000000006395 86.0
HKD2_k127_8531061_4 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000001222 59.0
HKD2_k127_8531061_5 nuclease of the RecB family - - - 0.0000001128 61.0
HKD2_k127_8531061_6 Ribbon-helix-helix domain - - - 0.000006658 50.0
HKD2_k127_8531061_7 Iron-sulfur cluster assembly accessory protein K13628 - - 0.0007856 46.0
HKD2_k127_86245_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 5.92e-272 852.0
HKD2_k127_86245_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.653e-236 756.0
HKD2_k127_86245_2 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 489.0
HKD2_k127_86245_3 COG2805 Tfp pilus assembly protein, pilus retraction ATPase PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 470.0
HKD2_k127_86245_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 455.0
HKD2_k127_86245_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000002444 198.0
HKD2_k127_86245_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000002977 160.0
HKD2_k127_86245_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000001488 128.0
HKD2_k127_86245_8 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000002343 121.0
HKD2_k127_86245_9 structural constituent of ribosome K02916 - - 0.000000000000000008586 86.0
HKD2_k127_8735384_0 Nickel-dependent hydrogenase K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 512.0
HKD2_k127_8735384_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 351.0
HKD2_k127_8735384_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 292.0
HKD2_k127_8735384_3 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 263.0
HKD2_k127_8735384_4 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000006547 153.0
HKD2_k127_8735384_5 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000004706 148.0
HKD2_k127_8735384_6 homoserine transmembrane transporter activity - - - 0.0000000000007413 77.0
HKD2_k127_8735384_7 spore germination K03605 - - 0.00000009268 62.0
HKD2_k127_8735384_8 Helix-turn-helix XRE-family like proteins - - - 0.00004046 47.0
HKD2_k127_8903058_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 606.0
HKD2_k127_8903058_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 309.0
HKD2_k127_8903058_2 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.000000000000000000000000000000000000000000000001652 190.0
HKD2_k127_8903058_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000001849 154.0
HKD2_k127_8949782_0 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 383.0
HKD2_k127_8949782_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000003941 192.0
HKD2_k127_8949782_2 GlcNAc-PI de-N-acetylase - - - 0.0000000001 64.0
HKD2_k127_8949782_3 Ribbon-helix-helix domain - - - 0.0000001014 55.0
HKD2_k127_8972165_0 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000008192 218.0
HKD2_k127_8972165_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000008286 184.0
HKD2_k127_8972165_2 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000000000000000000000000000000000000000007501 167.0
HKD2_k127_8972165_3 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000004664 158.0
HKD2_k127_8972165_4 Iron only hydrogenase large subunit, C-terminal domain - - - 0.0000000001163 64.0
HKD2_k127_8980425_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 314.0
HKD2_k127_8980425_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 292.0
HKD2_k127_8980425_2 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000003523 232.0
HKD2_k127_8980425_3 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000001646 175.0
HKD2_k127_8980425_4 RNA recognition motif - - - 0.00000000000000000000000000001349 119.0
HKD2_k127_8980425_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000008175 116.0
HKD2_k127_8980425_6 PFAM regulatory protein TetR K13770 - - 0.000000000006335 66.0
HKD2_k127_8980425_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000002971 55.0
HKD2_k127_9023078_0 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 556.0
HKD2_k127_9023078_1 Pterin binding enzyme K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 337.0
HKD2_k127_9023078_2 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000001991 207.0
HKD2_k127_9023078_3 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.000000000000000000001192 95.0
HKD2_k127_9039840_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.404e-209 670.0
HKD2_k127_9039840_1 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 438.0
HKD2_k127_9039840_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
HKD2_k127_9039840_3 PFAM HD domain - - - 0.000000000000000000000000003224 113.0
HKD2_k127_9039840_4 Membrane proteins related to metalloendopeptidases K06194 - - 0.000000000000000000000003352 106.0
HKD2_k127_9059133_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 457.0
HKD2_k127_9059133_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 394.0
HKD2_k127_9059133_10 - - - - 0.0000000000000000000000000000000000000004349 158.0
HKD2_k127_9059133_2 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 387.0
HKD2_k127_9059133_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 383.0
HKD2_k127_9059133_4 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003136 267.0
HKD2_k127_9059133_5 PFAM Peptidase M23 K21471 - - 0.0000000000000000000000000000000000000000000000000000004249 209.0
HKD2_k127_9059133_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000003114 194.0
HKD2_k127_9059133_7 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000001495 196.0
HKD2_k127_9059133_8 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000001602 193.0
HKD2_k127_9059133_9 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000004175 173.0
HKD2_k127_9064065_0 acetyl-CoA hydrolase transferase - - - 9.306e-212 674.0
HKD2_k127_9064065_1 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000003271 111.0
HKD2_k127_9064065_2 PFAM MltA K08304 - - 0.000000000001005 69.0
HKD2_k127_9110099_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 518.0
HKD2_k127_9110099_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000004289 208.0
HKD2_k127_9110099_2 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000003441 155.0
HKD2_k127_9121282_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 445.0
HKD2_k127_9121282_1 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 362.0
HKD2_k127_9121282_2 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
HKD2_k127_9121282_3 cell wall organization K01448 - 3.5.1.28 0.000000000257 70.0
HKD2_k127_9138407_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 4.242e-199 632.0
HKD2_k127_9138407_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 560.0
HKD2_k127_9138407_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001047 273.0
HKD2_k127_9160929_0 PFAM CobN Magnesium Chelatase K02230,K03403 - 6.6.1.1,6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 518.0
HKD2_k127_9160929_1 Bacterial regulatory protein, Fis family K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 296.0
HKD2_k127_9160929_2 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001236 247.0
HKD2_k127_9160929_3 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000004863 113.0
HKD2_k127_9160929_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000001155 102.0
HKD2_k127_9190038_0 Belongs to the ClpX chaperone family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 588.0
HKD2_k127_9190038_1 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 355.0
HKD2_k127_9190038_2 heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 324.0
HKD2_k127_9190038_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000003084 153.0
HKD2_k127_9190038_4 Amidohydrolase - - - 0.00000000000000000000000000000001069 138.0
HKD2_k127_9190038_5 Tetratricopeptide repeat-like domain - - - 0.000000000000000003151 94.0
HKD2_k127_9190038_6 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000003048 91.0
HKD2_k127_9224918_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.075e-314 979.0
HKD2_k127_9224918_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 325.0
HKD2_k127_9224918_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 301.0
HKD2_k127_9224918_3 YGGT family K02221 - - 0.000000000000000000000000000000002061 132.0
HKD2_k127_9224918_4 DUF167 K09131 - - 0.00000000000000000000000006425 109.0
HKD2_k127_9224918_5 DivIVA protein K04074 - - 0.0000000000000000000001012 104.0
HKD2_k127_9224918_6 - - - - 0.000000003487 59.0
HKD2_k127_9232861_0 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 312.0
HKD2_k127_9232861_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000107 182.0
HKD2_k127_9232861_2 Protein of unknown function (DUF1329) - - - 0.0009906 45.0
HKD2_k127_9253530_0 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 314.0
HKD2_k127_9253530_1 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000004039 265.0
HKD2_k127_9253530_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000002869 153.0
HKD2_k127_9255648_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 319.0
HKD2_k127_9255648_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 300.0
HKD2_k127_9255648_2 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 295.0
HKD2_k127_9255648_3 PFAM amidohydrolase 2 K07045 - - 0.00000000000000000000000000000000000000000000000435 183.0
HKD2_k127_9255648_4 MFS/sugar transport protein - - - 0.000000000005857 70.0
HKD2_k127_9255648_5 Periplasmic or secreted lipoprotein - - - 0.0000000001722 64.0
HKD2_k127_9255648_6 PFAM secretion protein HlyD family protein K01993 - - 0.0000000006119 60.0
HKD2_k127_9255648_7 Periplasmic or secreted lipoprotein - - - 0.000000002074 66.0
HKD2_k127_9255648_8 DNA excision K02806 - - 0.00001992 49.0
HKD2_k127_9260700_0 Transketolase, pyrimidine binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 379.0
HKD2_k127_9260700_1 E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 339.0
HKD2_k127_9260700_2 Bacterial capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000001265 162.0
HKD2_k127_9260700_3 Phosphotriesterase family K07048 - - 0.000000000000000008304 86.0
HKD2_k127_9269772_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.344e-206 651.0
HKD2_k127_9269772_1 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 546.0
HKD2_k127_9269772_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000001609 153.0
HKD2_k127_9269772_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000002066 112.0
HKD2_k127_9278939_0 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000004572 234.0
HKD2_k127_9278939_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10819 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000006386 235.0
HKD2_k127_9285491_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 408.0
HKD2_k127_9285491_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003451 254.0
HKD2_k127_9285491_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000000000000000000000001085 139.0
HKD2_k127_9285491_3 Ribbon-helix-helix protein, copG family - - - 0.00000000000209 73.0
HKD2_k127_9303558_0 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 559.0
HKD2_k127_9303558_1 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 391.0
HKD2_k127_9303558_2 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 402.0
HKD2_k127_9303558_3 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000113 193.0
HKD2_k127_9303558_4 PFAM CobN magnesium chelatase K02230 - 6.6.1.2 0.00000000000000000000000000000000000000001785 160.0
HKD2_k127_9303558_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000009368 152.0
HKD2_k127_9310277_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00366,K00392 - 1.7.7.1,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 376.0
HKD2_k127_9310277_1 PFAM metal-dependent phosphohydrolase HD sub - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 354.0
HKD2_k127_9310277_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 316.0
HKD2_k127_9310277_3 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 293.0
HKD2_k127_9310277_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000001975 227.0
HKD2_k127_9356707_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 548.0
HKD2_k127_9356707_1 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009714 282.0
HKD2_k127_9356707_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000015 68.0
HKD2_k127_9389044_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
HKD2_k127_9389044_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000002718 221.0
HKD2_k127_9389044_2 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000004867 143.0
HKD2_k127_939522_0 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 389.0
HKD2_k127_939522_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002969 242.0
HKD2_k127_939522_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000007817 220.0
HKD2_k127_939522_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000001606 125.0
HKD2_k127_939522_4 cobalamin binding K22491 - - 0.0006089 44.0
HKD2_k127_9451088_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 339.0
HKD2_k127_9451088_1 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000264 250.0
HKD2_k127_9451088_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000001484 151.0
HKD2_k127_9451088_3 Tetratricopeptide repeat - - - 0.0000001994 57.0
HKD2_k127_9467267_0 Psort location CytoplasmicMembrane, score 10.00 K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 534.0
HKD2_k127_9467267_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000002726 173.0
HKD2_k127_95081_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 4.447e-267 833.0
HKD2_k127_95081_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 409.0
HKD2_k127_95081_2 Involved in the tonB-independent uptake of proteins K13669 - - 0.000000007151 67.0
HKD2_k127_9701803_0 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 391.0
HKD2_k127_9701803_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000001659 222.0
HKD2_k127_9701803_2 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000000252 122.0
HKD2_k127_9701803_3 response regulator K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000002309 104.0
HKD2_k127_9754587_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 376.0
HKD2_k127_9754587_1 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
HKD2_k127_9754587_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000006991 87.0
HKD2_k127_9819340_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 352.0
HKD2_k127_9819340_1 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000006691 192.0
HKD2_k127_995787_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 376.0
HKD2_k127_995787_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 366.0
HKD2_k127_995787_2 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001335 258.0