logo

Overview

ID MAG01782
Name HKD2_bin.23
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_B
Class Binatia
Order HRBIN30
Family JAGDMS01
Genus
Species
Assembly information
Completeness (%) 89.11
Contamination (%) 2.66
GC content (%) 68.0
N50 (bp) 22,715
Genome size (bp) 3,630,142

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3085

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10147623_0 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 376.0
HKD2_k127_10147623_1 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 353.0
HKD2_k127_10147623_10 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000001413 145.0
HKD2_k127_10147623_11 Limonene-1,2-epoxide hydrolase - - - 0.0000000000000000000000000000008392 127.0
HKD2_k127_10147623_12 Protein of unknown function (DUF2889) - - - 0.000000000001275 75.0
HKD2_k127_10147623_13 - - - - 0.000000000005956 71.0
HKD2_k127_10147623_2 lactate metabolic process K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 308.0
HKD2_k127_10147623_3 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002957 294.0
HKD2_k127_10147623_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002555 295.0
HKD2_k127_10147623_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001372 274.0
HKD2_k127_10147623_6 Secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000005296 239.0
HKD2_k127_10147623_7 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000087 235.0
HKD2_k127_10147623_8 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000009769 198.0
HKD2_k127_10147623_9 May be involved in the biosynthesis of molybdopterin K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000006802 177.0
HKD2_k127_10173441_0 Glycosyl transferases group 1 K12989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 381.0
HKD2_k127_10173441_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007009 274.0
HKD2_k127_10173441_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001649 250.0
HKD2_k127_10173441_3 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000004126 208.0
HKD2_k127_10173441_4 - - - - 0.000000000000000000000000000000005794 145.0
HKD2_k127_10173441_5 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000004731 109.0
HKD2_k127_10173441_6 GCN5 family acetyltransferase - - - 0.00000000000000000004006 101.0
HKD2_k127_10173441_7 Protein of unknown function (DUF2492) - - - 0.0000000000000000001378 93.0
HKD2_k127_10173441_8 SnoaL-like domain - - - 0.0000002506 61.0
HKD2_k127_1131573_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.701e-259 815.0
HKD2_k127_1131573_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 346.0
HKD2_k127_1131573_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000004497 224.0
HKD2_k127_1131573_3 Thiol disulfide interchange protein dsbA - - - 0.0000000000000000000000000000000001525 147.0
HKD2_k127_1131573_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000002778 106.0
HKD2_k127_1131573_5 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000001663 100.0
HKD2_k127_122540_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1148.0
HKD2_k127_122540_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 1.231e-297 925.0
HKD2_k127_122540_11 Protein of unknown function (DUF1329) - - - 0.00000000000000000000001033 115.0
HKD2_k127_122540_12 Dimerisation domain - - - 0.0000000000000001426 81.0
HKD2_k127_122540_13 Sh3 type 3 domain protein - - - 0.000000000001024 81.0
HKD2_k127_122540_14 Transcription factor zinc-finger K09981 - - 0.000000002264 66.0
HKD2_k127_122540_15 - - - - 0.00000005879 59.0
HKD2_k127_122540_2 Glutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 601.0
HKD2_k127_122540_3 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 547.0
HKD2_k127_122540_4 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 408.0
HKD2_k127_122540_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15785 - 2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 369.0
HKD2_k127_122540_6 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 313.0
HKD2_k127_122540_7 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 319.0
HKD2_k127_122540_8 COGs COG0680 Ni Fe-hydrogenase maturation factor K03605 - - 0.0000000000000000000000000000000000000002351 157.0
HKD2_k127_122540_9 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000001005 150.0
HKD2_k127_126611_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 361.0
HKD2_k127_126611_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 358.0
HKD2_k127_126611_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009668 263.0
HKD2_k127_126611_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000003593 180.0
HKD2_k127_126611_4 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000000000003271 135.0
HKD2_k127_1282851_0 4Fe-4S dicluster domain K00184 - - 0.0 1225.0
HKD2_k127_1282851_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.264e-278 866.0
HKD2_k127_1282851_10 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 542.0
HKD2_k127_1282851_11 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 542.0
HKD2_k127_1282851_12 belongs to the aldehyde dehydrogenase family K00135,K08324 GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009060,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044464,GO:0045333,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 522.0
HKD2_k127_1282851_13 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 424.0
HKD2_k127_1282851_14 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 413.0
HKD2_k127_1282851_15 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 411.0
HKD2_k127_1282851_16 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 415.0
HKD2_k127_1282851_17 Uncharacterized protein family UPF0004 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 392.0
HKD2_k127_1282851_18 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 382.0
HKD2_k127_1282851_19 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 379.0
HKD2_k127_1282851_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.218e-246 766.0
HKD2_k127_1282851_20 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 387.0
HKD2_k127_1282851_21 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 372.0
HKD2_k127_1282851_22 Elongator protein 3, MiaB family, Radical SAM K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 357.0
HKD2_k127_1282851_23 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 333.0
HKD2_k127_1282851_24 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 318.0
HKD2_k127_1282851_25 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 312.0
HKD2_k127_1282851_26 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 319.0
HKD2_k127_1282851_27 ThiJ PfpI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 304.0
HKD2_k127_1282851_28 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 295.0
HKD2_k127_1282851_29 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000012 300.0
HKD2_k127_1282851_3 Succinyl-CoA ligase like flavodoxin domain - - - 3.378e-245 785.0
HKD2_k127_1282851_30 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000187 282.0
HKD2_k127_1282851_31 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001847 251.0
HKD2_k127_1282851_32 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000006797 246.0
HKD2_k127_1282851_33 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000265 247.0
HKD2_k127_1282851_34 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000001006 237.0
HKD2_k127_1282851_35 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000001593 237.0
HKD2_k127_1282851_36 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000003593 228.0
HKD2_k127_1282851_37 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000002288 236.0
HKD2_k127_1282851_38 Mate efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000001709 211.0
HKD2_k127_1282851_39 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000011 199.0
HKD2_k127_1282851_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.491e-240 751.0
HKD2_k127_1282851_40 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000005537 181.0
HKD2_k127_1282851_41 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000003812 175.0
HKD2_k127_1282851_42 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000003828 183.0
HKD2_k127_1282851_43 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000001009 154.0
HKD2_k127_1282851_44 RES - - - 0.000000000000000000000000000000000000003025 156.0
HKD2_k127_1282851_45 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000009822 154.0
HKD2_k127_1282851_46 R3H domain protein K06346 - - 0.0000000000000000000000000000000000004604 149.0
HKD2_k127_1282851_47 - - - - 0.000000000000000000000000000000000003676 149.0
HKD2_k127_1282851_48 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000005077 138.0
HKD2_k127_1282851_49 response to oxidative stress - - - 0.0000000000000000000000000000007746 127.0
HKD2_k127_1282851_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 4.181e-225 713.0
HKD2_k127_1282851_50 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000002158 127.0
HKD2_k127_1282851_51 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.00000000000000000000000001877 117.0
HKD2_k127_1282851_52 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000001216 114.0
HKD2_k127_1282851_53 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000002958 108.0
HKD2_k127_1282851_54 Polymer-forming cytoskeletal - - - 0.0000000000000000000000008829 110.0
HKD2_k127_1282851_55 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000008514 103.0
HKD2_k127_1282851_56 Prostaglandin E synthase K00799,K15729 GO:0001516,GO:0001676,GO:0003674,GO:0003824,GO:0004667,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005641,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008285,GO:0008610,GO:0009058,GO:0009987,GO:0010033,GO:0012505,GO:0016020,GO:0016021,GO:0016053,GO:0016853,GO:0016860,GO:0019369,GO:0019371,GO:0019752,GO:0023052,GO:0031224,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0031984,GO:0032787,GO:0033218,GO:0033559,GO:0034097,GO:0042127,GO:0042175,GO:0042221,GO:0042277,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043295,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046456,GO:0046457,GO:0048037,GO:0048471,GO:0048519,GO:0048523,GO:0050220,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070013,GO:0070555,GO:0070887,GO:0071310,GO:0071345,GO:0071347,GO:0071704,GO:0072330,GO:0072341,GO:0098827,GO:1900750,GO:1901568,GO:1901570,GO:1901576,GO:1901681 2.5.1.18,5.3.99.3 0.0000000000000000000003834 103.0
HKD2_k127_1282851_57 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000001162 102.0
HKD2_k127_1282851_58 Rieske [2Fe-2S] domain - - - 0.0000000000000000001447 95.0
HKD2_k127_1282851_59 - - - - 0.0000000000000000005499 91.0
HKD2_k127_1282851_6 Polysulphide reductase, NrfD K00185 - - 1.126e-223 701.0
HKD2_k127_1282851_60 anaerobic respiration - - - 0.000000000000000002162 93.0
HKD2_k127_1282851_61 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.000000000000000003894 96.0
HKD2_k127_1282851_62 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.00000000000000004963 89.0
HKD2_k127_1282851_63 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000685 86.0
HKD2_k127_1282851_64 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000005151 75.0
HKD2_k127_1282851_65 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000005631 87.0
HKD2_k127_1282851_66 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000003607 74.0
HKD2_k127_1282851_67 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000738 68.0
HKD2_k127_1282851_68 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000008885 70.0
HKD2_k127_1282851_69 - - - - 0.0000002852 63.0
HKD2_k127_1282851_7 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 2.419e-203 640.0
HKD2_k127_1282851_70 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000005779 57.0
HKD2_k127_1282851_72 reductase - - - 0.0007624 50.0
HKD2_k127_1282851_8 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.147e-201 649.0
HKD2_k127_1282851_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 561.0
HKD2_k127_1294406_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 437.0
HKD2_k127_1294406_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 394.0
HKD2_k127_1294406_2 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 342.0
HKD2_k127_1294406_3 Rnd family efflux transporter mfp subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 318.0
HKD2_k127_1294406_4 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000004294 247.0
HKD2_k127_1325555_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1382.0
HKD2_k127_1325555_1 PFAM Glycoside hydrolase 15-related - - - 0.0 1105.0
HKD2_k127_1325555_10 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 446.0
HKD2_k127_1325555_11 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 432.0
HKD2_k127_1325555_12 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 396.0
HKD2_k127_1325555_13 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 389.0
HKD2_k127_1325555_14 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 296.0
HKD2_k127_1325555_15 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
HKD2_k127_1325555_16 chorismate binding enzyme K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001561 289.0
HKD2_k127_1325555_17 short chain dehydrogenase reductase family K18009 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 273.0
HKD2_k127_1325555_18 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003634 274.0
HKD2_k127_1325555_19 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000008694 254.0
HKD2_k127_1325555_2 Alpha/beta hydrolase family K03821,K03822 - - 6.784e-308 975.0
HKD2_k127_1325555_20 Acyl- CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000013 231.0
HKD2_k127_1325555_21 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000293 205.0
HKD2_k127_1325555_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000001064 204.0
HKD2_k127_1325555_23 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000463 203.0
HKD2_k127_1325555_24 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000006819 170.0
HKD2_k127_1325555_25 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) - - - 0.0000000000000000000000000000008642 138.0
HKD2_k127_1325555_26 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000292 123.0
HKD2_k127_1325555_27 Multicopper oxidase K04753 - - 0.0000000000000000003023 104.0
HKD2_k127_1325555_28 transcriptional - - - 0.000000000000000002379 94.0
HKD2_k127_1325555_29 Psort location CytoplasmicMembrane, score K02237 - - 0.000000000000000008232 87.0
HKD2_k127_1325555_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.691e-235 738.0
HKD2_k127_1325555_30 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000004553 60.0
HKD2_k127_1325555_4 PFAM ABC transporter K02471 - - 6.221e-195 626.0
HKD2_k127_1325555_5 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 594.0
HKD2_k127_1325555_6 peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 591.0
HKD2_k127_1325555_7 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 503.0
HKD2_k127_1325555_8 COGs COG0318 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 484.0
HKD2_k127_1325555_9 Enoyl-CoA hydratase/isomerase K01661 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071890,GO:0071944,GO:1901576,GO:1901661,GO:1901663 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 446.0
HKD2_k127_1335732_0 alpha beta alpha domain I K01835 - 5.4.2.2 8.42e-268 837.0
HKD2_k127_1335732_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.126e-221 716.0
HKD2_k127_1335732_2 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 619.0
HKD2_k127_1335732_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 329.0
HKD2_k127_1335732_4 DEAD/H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 310.0
HKD2_k127_1335732_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 296.0
HKD2_k127_1335732_6 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001197 293.0
HKD2_k127_1335732_7 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000004519 106.0
HKD2_k127_1335732_8 ParB-like nuclease domain K03497 - - 0.0002944 52.0
HKD2_k127_1339308_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 2.231e-306 966.0
HKD2_k127_1339308_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 2.086e-276 869.0
HKD2_k127_1339308_2 Von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 363.0
HKD2_k127_1339308_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000005799 251.0
HKD2_k127_1339308_4 Fic/DOC family K07341 - - 0.00000000000000000000000000000000000000000000000714 175.0
HKD2_k127_1339308_5 PFAM Ribbon-helix-helix protein, copG family K21495 - - 0.00000000000007826 74.0
HKD2_k127_1339308_6 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.00000001652 56.0
HKD2_k127_1354787_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1065.0
HKD2_k127_1354787_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.75e-303 948.0
HKD2_k127_1354787_10 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 327.0
HKD2_k127_1354787_11 Peptidase family C69 K14358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002417 278.0
HKD2_k127_1354787_12 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000002508 240.0
HKD2_k127_1354787_13 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000002678 232.0
HKD2_k127_1354787_14 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000003368 222.0
HKD2_k127_1354787_15 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000005292 179.0
HKD2_k127_1354787_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000002677 185.0
HKD2_k127_1354787_17 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000002089 160.0
HKD2_k127_1354787_18 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000003533 102.0
HKD2_k127_1354787_19 efflux transmembrane transporter activity K15725 - - 0.00000000000000000000206 109.0
HKD2_k127_1354787_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.51e-284 897.0
HKD2_k127_1354787_20 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000002377 100.0
HKD2_k127_1354787_21 Bacterial Ig-like domain 2 - - - 0.00000000000000000002395 108.0
HKD2_k127_1354787_22 haloacid dehalogenase K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.00000000000000000008436 98.0
HKD2_k127_1354787_23 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000005188 92.0
HKD2_k127_1354787_24 Domain of unknown function (DUF4149) - - - 0.000000009115 67.0
HKD2_k127_1354787_3 Transglycosylase - - - 5.436e-244 797.0
HKD2_k127_1354787_4 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 5.064e-199 647.0
HKD2_k127_1354787_5 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 452.0
HKD2_k127_1354787_6 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 415.0
HKD2_k127_1354787_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 351.0
HKD2_k127_1354787_8 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 361.0
HKD2_k127_1354787_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 316.0
HKD2_k127_1365811_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1224.0
HKD2_k127_1365811_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 602.0
HKD2_k127_1365811_10 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000009745 258.0
HKD2_k127_1365811_11 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000245 231.0
HKD2_k127_1365811_12 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000212 202.0
HKD2_k127_1365811_13 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000002363 209.0
HKD2_k127_1365811_14 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000001691 193.0
HKD2_k127_1365811_15 nitrate reductase molybdenum cofactor assembly chaperone K17052 - - 0.000000000000000000000000000000000000000000000000005105 188.0
HKD2_k127_1365811_16 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000001207 147.0
HKD2_k127_1365811_17 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000389 137.0
HKD2_k127_1365811_18 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000001427 130.0
HKD2_k127_1365811_19 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.0000000000000000000000000000002417 127.0
HKD2_k127_1365811_2 Sigma-54 interaction domain K15836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 550.0
HKD2_k127_1365811_20 Transcriptional regulator, Crp Fnr family K01420 - - 0.000000000000000000000001395 113.0
HKD2_k127_1365811_21 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000175 107.0
HKD2_k127_1365811_23 TIGRFAM alpha-glucan - - - 0.000000000000000002486 88.0
HKD2_k127_1365811_24 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000001355 83.0
HKD2_k127_1365811_25 Domain of unknown function (DUF4136) - - - 0.00000000000007671 80.0
HKD2_k127_1365811_26 ferrous iron import across plasma membrane - - - 0.000009414 53.0
HKD2_k127_1365811_3 4Fe-4S dicluster domain K17048,K17051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 478.0
HKD2_k127_1365811_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 470.0
HKD2_k127_1365811_5 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 385.0
HKD2_k127_1365811_6 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 304.0
HKD2_k127_1365811_7 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003858 275.0
HKD2_k127_1365811_9 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000001722 237.0
HKD2_k127_1371539_0 homoserine kinase activity K02204 - 2.7.1.39 0.0 1057.0
HKD2_k127_1371539_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 1.109e-258 818.0
HKD2_k127_1371539_10 DoxX-like family K15977 - - 0.00000000000000000000000002416 119.0
HKD2_k127_1371539_11 Putative DNA-binding domain - - - 0.000000000000000000001402 105.0
HKD2_k127_1371539_12 - - - - 0.0000000002893 66.0
HKD2_k127_1371539_13 Putative zinc-finger - - - 0.000000001809 63.0
HKD2_k127_1371539_14 - - - - 0.0000002918 57.0
HKD2_k127_1371539_15 Major Facilitator Superfamily - - - 0.0000007176 53.0
HKD2_k127_1371539_16 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.0001942 49.0
HKD2_k127_1371539_17 mechanosensitive ion channel - - - 0.0007477 48.0
HKD2_k127_1371539_2 choline dehydrogenase activity - - - 1.542e-218 702.0
HKD2_k127_1371539_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 420.0
HKD2_k127_1371539_4 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 397.0
HKD2_k127_1371539_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 364.0
HKD2_k127_1371539_6 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 344.0
HKD2_k127_1371539_7 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009801 340.0
HKD2_k127_1371539_8 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000184 182.0
HKD2_k127_1371539_9 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000003684 117.0
HKD2_k127_1392890_0 FAD linked oxidase domain protein - - - 0.0 1320.0
HKD2_k127_1392890_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.306e-283 878.0
HKD2_k127_1392890_11 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004869 282.0
HKD2_k127_1392890_12 - - - - 0.000000000000000000000000000000000000000000000000000000000001974 218.0
HKD2_k127_1392890_13 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000002468 205.0
HKD2_k127_1392890_14 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000000000000001233 138.0
HKD2_k127_1392890_15 - - - - 0.000000000000000000003552 96.0
HKD2_k127_1392890_16 PFAM Glycosyl transferase family 2 - - - 0.0000000008016 71.0
HKD2_k127_1392890_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 3.03e-269 854.0
HKD2_k127_1392890_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.345e-261 817.0
HKD2_k127_1392890_4 alpha amylase, catalytic region - - - 8.602e-221 694.0
HKD2_k127_1392890_5 Amino acid permease - - - 3.846e-220 700.0
HKD2_k127_1392890_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 557.0
HKD2_k127_1392890_7 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 503.0
HKD2_k127_1392890_8 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 391.0
HKD2_k127_1392890_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 332.0
HKD2_k127_1405870_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 8.681e-233 753.0
HKD2_k127_1405870_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 5.621e-232 744.0
HKD2_k127_1405870_10 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000001422 200.0
HKD2_k127_1405870_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000005489 168.0
HKD2_k127_1405870_12 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000005017 154.0
HKD2_k127_1405870_13 dihydroorotate dehydrogenase K17723 - 1.3.1.1 0.00000000000000000000000000000000004795 151.0
HKD2_k127_1405870_14 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000006602 140.0
HKD2_k127_1405870_15 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000002621 143.0
HKD2_k127_1405870_16 Calcium/calmodulin dependent protein kinase II association domain - - - 0.0000000000000000000000000000002136 134.0
HKD2_k127_1405870_17 FixH K09926 - - 0.000000000000000000000000000003459 125.0
HKD2_k127_1405870_18 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000000002902 115.0
HKD2_k127_1405870_19 Methylmuconolactone methyl-isomerase - - - 0.0000000000000000000008331 105.0
HKD2_k127_1405870_2 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 1.807e-215 686.0
HKD2_k127_1405870_20 - - - - 0.000000000000003307 83.0
HKD2_k127_1405870_21 Cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000001899 75.0
HKD2_k127_1405870_22 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000003111 64.0
HKD2_k127_1405870_23 - - - - 0.0000000006801 60.0
HKD2_k127_1405870_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 439.0
HKD2_k127_1405870_4 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 311.0
HKD2_k127_1405870_5 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001425 286.0
HKD2_k127_1405870_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002853 258.0
HKD2_k127_1405870_7 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000000000007525 217.0
HKD2_k127_1405870_8 COG0348 Polyferredoxin - - - 0.00000000000000000000000000000000000000000000000000000001526 203.0
HKD2_k127_1405870_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000003454 201.0
HKD2_k127_1438302_0 lipopolysaccharide transport K22110 - - 0.0 1395.0
HKD2_k127_1438302_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.092e-265 829.0
HKD2_k127_1438302_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000005748 163.0
HKD2_k127_1438302_11 B-1 B cell differentiation - - - 0.0000000000000000000000000000000004195 151.0
HKD2_k127_1438302_12 - - - - 0.0000000000000000000000000000001466 139.0
HKD2_k127_1438302_13 Transglycosylase associated protein - - - 0.000000000000000000000000000004748 121.0
HKD2_k127_1438302_14 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000001941 79.0
HKD2_k127_1438302_15 Alpha beta hydrolase - - - 0.00000000004024 64.0
HKD2_k127_1438302_16 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0001459 51.0
HKD2_k127_1438302_2 Penicillin amidase K01434,K07116 - 3.5.1.11,3.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 598.0
HKD2_k127_1438302_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 563.0
HKD2_k127_1438302_4 Belongs to the TPP enzyme family K01652 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 508.0
HKD2_k127_1438302_5 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641,K15311 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 398.0
HKD2_k127_1438302_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 382.0
HKD2_k127_1438302_7 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 347.0
HKD2_k127_1438302_8 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000158 247.0
HKD2_k127_1438302_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000008514 213.0
HKD2_k127_1457421_0 Flavin-binding monooxygenase-like - - - 6.893e-287 893.0
HKD2_k127_1457421_1 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 316.0
HKD2_k127_1457421_2 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000001157 172.0
HKD2_k127_1457421_3 Cysteine rich repeat - - - 0.00000000002564 69.0
HKD2_k127_1503505_0 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 572.0
HKD2_k127_1503505_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 480.0
HKD2_k127_1503505_2 PFAM alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 361.0
HKD2_k127_1503505_3 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000007984 162.0
HKD2_k127_1503505_4 alkaline phosphatase K01113 - 3.1.3.1 0.000000000000001657 84.0
HKD2_k127_1503505_5 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 0.00000000000005165 74.0
HKD2_k127_1559464_0 formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 1.337e-312 985.0
HKD2_k127_1559464_1 Glycosyl hydrolase family 57 - - - 8.353e-247 775.0
HKD2_k127_1559464_10 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 322.0
HKD2_k127_1559464_11 Pfam:Kce - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003817 268.0
HKD2_k127_1559464_12 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007013 258.0
HKD2_k127_1559464_13 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000004467 220.0
HKD2_k127_1559464_14 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000002531 211.0
HKD2_k127_1559464_15 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000009224 211.0
HKD2_k127_1559464_16 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000003512 188.0
HKD2_k127_1559464_17 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000002146 173.0
HKD2_k127_1559464_18 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000001426 179.0
HKD2_k127_1559464_19 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000144 175.0
HKD2_k127_1559464_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 3.294e-234 734.0
HKD2_k127_1559464_20 Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.0000000000000000000004176 106.0
HKD2_k127_1559464_21 Belongs to the 'phage' integrase family - - - 0.000000000000000000004781 98.0
HKD2_k127_1559464_22 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.00000000000003893 85.0
HKD2_k127_1559464_23 - - - - 0.0000000006816 69.0
HKD2_k127_1559464_3 Acyl-coa dehydrogenase K00249 - 1.3.8.7 2.614e-202 637.0
HKD2_k127_1559464_4 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 572.0
HKD2_k127_1559464_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 512.0
HKD2_k127_1559464_6 Dehydrogenase K00055 - 1.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 446.0
HKD2_k127_1559464_7 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 395.0
HKD2_k127_1559464_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 352.0
HKD2_k127_1559464_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 340.0
HKD2_k127_1633846_0 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 593.0
HKD2_k127_1633846_1 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 526.0
HKD2_k127_1633846_10 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000003172 112.0
HKD2_k127_1633846_11 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000001222 59.0
HKD2_k127_1633846_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 514.0
HKD2_k127_1633846_3 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 467.0
HKD2_k127_1633846_4 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 442.0
HKD2_k127_1633846_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0030312,GO:0040007,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0071944,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22,4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 357.0
HKD2_k127_1633846_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 258.0
HKD2_k127_1633846_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000003217 223.0
HKD2_k127_1633846_8 peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000003538 207.0
HKD2_k127_1633846_9 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000005427 186.0
HKD2_k127_1777424_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 6.305e-269 838.0
HKD2_k127_1777424_1 protein conserved in bacteria - - - 4.742e-227 711.0
HKD2_k127_1777424_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 368.0
HKD2_k127_1777424_11 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 366.0
HKD2_k127_1777424_12 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 316.0
HKD2_k127_1777424_13 Psort location Cytoplasmic, score K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004424 306.0
HKD2_k127_1777424_14 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002777 266.0
HKD2_k127_1777424_15 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008871 278.0
HKD2_k127_1777424_16 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 263.0
HKD2_k127_1777424_17 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 259.0
HKD2_k127_1777424_18 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000004257 219.0
HKD2_k127_1777424_19 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000000007366 209.0
HKD2_k127_1777424_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.021e-215 691.0
HKD2_k127_1777424_20 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000000000000000000000007568 213.0
HKD2_k127_1777424_21 enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000005591 201.0
HKD2_k127_1777424_22 Protein of unknown function (DUF445) - - - 0.000000000000000000000000000000000000000000000000005995 199.0
HKD2_k127_1777424_23 methyltransferase - - - 0.00000000000000000000000000000000000000000002241 169.0
HKD2_k127_1777424_24 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000000000000000000000001296 160.0
HKD2_k127_1777424_25 DNA polymerase III, delta' K02340 - 2.7.7.7 0.0000000000000000000000000000000000000001864 168.0
HKD2_k127_1777424_26 PFAM Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000001482 149.0
HKD2_k127_1777424_27 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000001279 132.0
HKD2_k127_1777424_28 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000002582 125.0
HKD2_k127_1777424_29 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0000000000000000000000000004425 125.0
HKD2_k127_1777424_3 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 541.0
HKD2_k127_1777424_30 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000246 102.0
HKD2_k127_1777424_31 Sodium Bile acid symporter family - - - 0.000000000000000007764 94.0
HKD2_k127_1777424_32 - - - - 0.000000000000001034 90.0
HKD2_k127_1777424_33 Thioredoxin - - - 0.000000178 61.0
HKD2_k127_1777424_34 methyltransferase activity K21310 - 2.1.1.334 0.0000004332 60.0
HKD2_k127_1777424_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 526.0
HKD2_k127_1777424_5 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 526.0
HKD2_k127_1777424_6 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 479.0
HKD2_k127_1777424_7 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 395.0
HKD2_k127_1777424_8 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 380.0
HKD2_k127_1777424_9 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 383.0
HKD2_k127_1793665_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1423.0
HKD2_k127_1793665_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.81e-259 812.0
HKD2_k127_1793665_10 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 359.0
HKD2_k127_1793665_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005814 285.0
HKD2_k127_1793665_12 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001688 257.0
HKD2_k127_1793665_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001664 222.0
HKD2_k127_1793665_14 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis - - - 0.00000000000000000000000000000000000000000000000000006303 204.0
HKD2_k127_1793665_15 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000231 195.0
HKD2_k127_1793665_16 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000003014 180.0
HKD2_k127_1793665_17 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000001214 153.0
HKD2_k127_1793665_18 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.00000000000000000000000000000000000002246 147.0
HKD2_k127_1793665_19 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000001474 149.0
HKD2_k127_1793665_2 Protein of unknown function, DUF255 K06888 - - 1.048e-210 676.0
HKD2_k127_1793665_20 CBS domain K04767,K07168,K07182 - - 0.000000000000000000000000000000002046 136.0
HKD2_k127_1793665_21 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000007255 136.0
HKD2_k127_1793665_22 Hemerythrin HHE cation binding domain - - - 0.00000000002379 74.0
HKD2_k127_1793665_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 589.0
HKD2_k127_1793665_4 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 476.0
HKD2_k127_1793665_5 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 446.0
HKD2_k127_1793665_6 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 441.0
HKD2_k127_1793665_7 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 430.0
HKD2_k127_1793665_8 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 428.0
HKD2_k127_1793665_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 407.0
HKD2_k127_1896282_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1178.0
HKD2_k127_1896282_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.844e-212 672.0
HKD2_k127_1896282_10 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003211 254.0
HKD2_k127_1896282_11 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000009552 232.0
HKD2_k127_1896282_12 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000004745 205.0
HKD2_k127_1896282_13 tRNA methyltransferase complex GCD14 subunit - - - 0.000000000000000000000000000000000000000000000001097 184.0
HKD2_k127_1896282_14 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000003575 135.0
HKD2_k127_1896282_15 Tetratricopeptide repeat - - - 0.00003276 54.0
HKD2_k127_1896282_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 2.74e-203 643.0
HKD2_k127_1896282_3 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 439.0
HKD2_k127_1896282_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 398.0
HKD2_k127_1896282_5 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 384.0
HKD2_k127_1896282_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 373.0
HKD2_k127_1896282_7 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 323.0
HKD2_k127_1896282_8 Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 306.0
HKD2_k127_1896282_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005393 282.0
HKD2_k127_1991600_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 377.0
HKD2_k127_1991600_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 311.0
HKD2_k127_1991600_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006159 240.0
HKD2_k127_2316554_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 7.782e-225 727.0
HKD2_k127_2316554_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 572.0
HKD2_k127_2316554_10 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000002726 173.0
HKD2_k127_2316554_11 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000003396 171.0
HKD2_k127_2316554_12 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000001776 154.0
HKD2_k127_2316554_13 protein conserved in bacteria - - - 0.00000000000000000000000000000001262 135.0
HKD2_k127_2316554_14 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000000593 134.0
HKD2_k127_2316554_15 Protein conserved in bacteria K09986 - - 0.000000000000000000003413 98.0
HKD2_k127_2316554_16 Transcription factor zinc-finger K09981 - - 0.00000000001493 74.0
HKD2_k127_2316554_17 Alpha/beta hydrolase family - - - 0.000000001722 68.0
HKD2_k127_2316554_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 482.0
HKD2_k127_2316554_3 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 374.0
HKD2_k127_2316554_4 Diacylglycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003633 275.0
HKD2_k127_2316554_5 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000853 243.0
HKD2_k127_2316554_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000799 244.0
HKD2_k127_2316554_7 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000443 235.0
HKD2_k127_2316554_8 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007303 226.0
HKD2_k127_2316554_9 LemA family K03744 - - 0.00000000000000000000000000000000000000000000001212 179.0
HKD2_k127_2370699_0 Biotin carboxylase C-terminal domain - - - 1.033e-293 915.0
HKD2_k127_2370699_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.007e-280 880.0
HKD2_k127_2370699_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.793e-247 803.0
HKD2_k127_2370699_3 Glycosyltransferase, group 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 488.0
HKD2_k127_2370699_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 344.0
HKD2_k127_2370699_5 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000001935 113.0
HKD2_k127_2370699_6 Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0000000000001523 74.0
HKD2_k127_255738_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 613.0
HKD2_k127_255738_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 593.0
HKD2_k127_255738_10 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000001412 228.0
HKD2_k127_255738_11 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000001894 226.0
HKD2_k127_255738_12 PFAM Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000001017 222.0
HKD2_k127_255738_13 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000966 201.0
HKD2_k127_255738_14 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000001634 143.0
HKD2_k127_255738_15 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000008808 135.0
HKD2_k127_255738_16 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000004359 132.0
HKD2_k127_255738_17 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000001721 112.0
HKD2_k127_255738_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 490.0
HKD2_k127_255738_3 ABC transporter, ATP-binding protein K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 423.0
HKD2_k127_255738_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 374.0
HKD2_k127_255738_5 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 336.0
HKD2_k127_255738_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 295.0
HKD2_k127_255738_7 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
HKD2_k127_255738_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000003424 256.0
HKD2_k127_255738_9 ATPase component of Mn Zn ABC-type transporter K09817,K09820 - - 0.00000000000000000000000000000000000000000000000000000000000000005752 234.0
HKD2_k127_2571319_0 reductase - - - 0.00000000000000000000000000000000000000000000000000000003955 207.0
HKD2_k127_2571319_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000002437 174.0
HKD2_k127_2571319_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000004825 110.0
HKD2_k127_2571319_4 Electron transfer flavoprotein FAD-binding domain K03522,K22432 - 1.3.1.108 0.0000000001332 66.0
HKD2_k127_2644479_0 Glycogen debranching enzyme - - - 0.0 1559.0
HKD2_k127_2644479_1 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0 1044.0
HKD2_k127_2644479_10 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 557.0
HKD2_k127_2644479_11 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 555.0
HKD2_k127_2644479_12 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 545.0
HKD2_k127_2644479_13 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 547.0
HKD2_k127_2644479_14 (ABC) transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 531.0
HKD2_k127_2644479_15 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 527.0
HKD2_k127_2644479_16 Quinohemoprotein amine dehydrogenase, alpha subunit domain II K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 456.0
HKD2_k127_2644479_17 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 451.0
HKD2_k127_2644479_18 ABC transporter K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 381.0
HKD2_k127_2644479_19 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 355.0
HKD2_k127_2644479_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.035e-317 981.0
HKD2_k127_2644479_20 4Fe-4S binding domain K08358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 356.0
HKD2_k127_2644479_21 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 338.0
HKD2_k127_2644479_22 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 332.0
HKD2_k127_2644479_23 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 327.0
HKD2_k127_2644479_24 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 316.0
HKD2_k127_2644479_25 Quinohemoprotein amine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 314.0
HKD2_k127_2644479_26 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 297.0
HKD2_k127_2644479_27 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 267.0
HKD2_k127_2644479_28 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005158 269.0
HKD2_k127_2644479_29 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008662 252.0
HKD2_k127_2644479_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.841e-311 964.0
HKD2_k127_2644479_30 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000005191 228.0
HKD2_k127_2644479_31 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000002662 234.0
HKD2_k127_2644479_32 Hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000001986 204.0
HKD2_k127_2644479_33 lipoprotein involved in nitrous oxide reduction K19342 - - 0.00000000000000000000000000000000000000000003616 168.0
HKD2_k127_2644479_34 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000229 149.0
HKD2_k127_2644479_35 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000045 138.0
HKD2_k127_2644479_36 3D domain - - - 0.00000000000000000000004194 107.0
HKD2_k127_2644479_38 - - - - 0.0000008974 54.0
HKD2_k127_2644479_39 GNAT family - - - 0.0000984 52.0
HKD2_k127_2644479_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 3.486e-224 707.0
HKD2_k127_2644479_5 Belongs to the glycosyl hydrolase 57 family - - - 3.501e-214 691.0
HKD2_k127_2644479_6 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 1.788e-201 641.0
HKD2_k127_2644479_7 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 605.0
HKD2_k127_2644479_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 584.0
HKD2_k127_2644479_9 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 582.0
HKD2_k127_2659502_0 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 570.0
HKD2_k127_2659502_1 PFAM 2-nitropropane dioxygenase NPD K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 516.0
HKD2_k127_2659502_10 Selenoprotein B glycine betaine sarcosine D-proline reductase K10794 - 1.21.4.1 0.0000000000000000000000000000000000000000000000002735 182.0
HKD2_k127_2659502_11 COGs COG2905 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000000002721 177.0
HKD2_k127_2659502_12 - - - - 0.0000000000000000000000000000000002047 136.0
HKD2_k127_2659502_13 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000008174 152.0
HKD2_k127_2659502_14 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000005762 119.0
HKD2_k127_2659502_15 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000004317 79.0
HKD2_k127_2659502_16 Belongs to the peptidase S8 family - - - 0.000000001466 71.0
HKD2_k127_2659502_2 Wax ester synthase-like Acyl-CoA acyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 437.0
HKD2_k127_2659502_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 377.0
HKD2_k127_2659502_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 371.0
HKD2_k127_2659502_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 350.0
HKD2_k127_2659502_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 303.0
HKD2_k127_2659502_7 Short-chain dehydrogenase reductase SDR K17754 - 1.1.1.163 0.000000000000000000000000000000000000000000000000000000000000000000001123 245.0
HKD2_k127_2659502_8 Lactamase, beta 2 - GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000001078 222.0
HKD2_k127_2659502_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000004005 204.0
HKD2_k127_2661597_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.985e-199 629.0
HKD2_k127_2661597_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 550.0
HKD2_k127_2661597_10 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 311.0
HKD2_k127_2661597_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 297.0
HKD2_k127_2661597_12 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 301.0
HKD2_k127_2661597_13 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008101 296.0
HKD2_k127_2661597_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009329 278.0
HKD2_k127_2661597_15 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003778 261.0
HKD2_k127_2661597_16 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003643 266.0
HKD2_k127_2661597_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000001018 256.0
HKD2_k127_2661597_18 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000005717 253.0
HKD2_k127_2661597_19 COG3243 Poly(3-hydroxyalkanoate) synthetase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001967 253.0
HKD2_k127_2661597_2 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 547.0
HKD2_k127_2661597_20 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000001523 233.0
HKD2_k127_2661597_21 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000304 220.0
HKD2_k127_2661597_22 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002086 211.0
HKD2_k127_2661597_23 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000003135 216.0
HKD2_k127_2661597_24 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001281 213.0
HKD2_k127_2661597_25 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000005802 195.0
HKD2_k127_2661597_26 Outer membrane lipoprotein Slp K07285 - - 0.0000000000000000000000000000000000000000000000000000237 194.0
HKD2_k127_2661597_27 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000006281 198.0
HKD2_k127_2661597_28 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000002649 184.0
HKD2_k127_2661597_29 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000004625 186.0
HKD2_k127_2661597_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 556.0
HKD2_k127_2661597_30 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000747 175.0
HKD2_k127_2661597_31 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000007673 173.0
HKD2_k127_2661597_32 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000005376 159.0
HKD2_k127_2661597_33 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000002247 153.0
HKD2_k127_2661597_34 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000002601 156.0
HKD2_k127_2661597_35 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000007169 143.0
HKD2_k127_2661597_36 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000001645 129.0
HKD2_k127_2661597_37 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000001134 130.0
HKD2_k127_2661597_38 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000944 119.0
HKD2_k127_2661597_39 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000005296 108.0
HKD2_k127_2661597_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 459.0
HKD2_k127_2661597_40 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000002882 96.0
HKD2_k127_2661597_41 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000001798 76.0
HKD2_k127_2661597_42 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000823 67.0
HKD2_k127_2661597_43 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000827 66.0
HKD2_k127_2661597_44 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000009022 66.0
HKD2_k127_2661597_45 Cadherin-like - - - 0.0000001963 64.0
HKD2_k127_2661597_46 Fibronectin, type III domain - - - 0.0000005751 62.0
HKD2_k127_2661597_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 374.0
HKD2_k127_2661597_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 348.0
HKD2_k127_2661597_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
HKD2_k127_2661597_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 321.0
HKD2_k127_2661597_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 316.0
HKD2_k127_2663357_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
HKD2_k127_2663357_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004975 212.0
HKD2_k127_2663357_2 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000001666 190.0
HKD2_k127_2663357_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000405 168.0
HKD2_k127_2663357_4 PFAM monooxygenase FAD-binding K20944 - 1.14.13.220 0.00002238 55.0
HKD2_k127_2677492_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.977e-206 646.0
HKD2_k127_2677492_1 Aldehyde dehydrogenase family - - - 9.154e-197 632.0
HKD2_k127_2677492_10 sulfolactate sulfo-lyase activity K01685,K01708 - 4.2.1.42,4.2.1.7 0.0000000000000001793 90.0
HKD2_k127_2677492_2 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 516.0
HKD2_k127_2677492_3 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 388.0
HKD2_k127_2677492_4 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 351.0
HKD2_k127_2677492_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
HKD2_k127_2677492_6 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000002369 246.0
HKD2_k127_2677492_7 Nitroreductase family - - - 0.0000000000000000000000000000000000000000164 162.0
HKD2_k127_2677492_8 YjbR - - - 0.000000000000000000000000000000000000004269 158.0
HKD2_k127_2677492_9 - - - - 0.000000000000000000000000000000000000009791 151.0
HKD2_k127_2680391_0 Squalene-hopene cyclase C-terminal domain K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 5.121e-226 720.0
HKD2_k127_2680391_1 Adenylate cyclase K01768 - 4.6.1.1 1.182e-215 683.0
HKD2_k127_2680391_10 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003656 289.0
HKD2_k127_2680391_11 ergosterol biosynthetic process K02291,K21679 - 2.5.1.32,2.5.1.99,4.2.3.156 0.0000000000000000000000000000000000000000000000000000000000000000000000000009753 279.0
HKD2_k127_2680391_12 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006385 261.0
HKD2_k127_2680391_13 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000514 255.0
HKD2_k127_2680391_14 Flavin containing amine oxidoreductase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000001573 251.0
HKD2_k127_2680391_15 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000008064 226.0
HKD2_k127_2680391_16 Hydroxymethylglutaryl-coenzyme A reductase K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000005533 221.0
HKD2_k127_2680391_17 GHMP kinases C terminal K00938 - 2.7.4.2 0.0000000000000000000000000000000000000002662 167.0
HKD2_k127_2680391_18 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000007201 135.0
HKD2_k127_2680391_19 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000006984 120.0
HKD2_k127_2680391_2 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 439.0
HKD2_k127_2680391_20 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000002731 104.0
HKD2_k127_2680391_21 - - - - 0.0000000000003948 75.0
HKD2_k127_2680391_22 Phosphorylase superfamily - - - 0.000006787 56.0
HKD2_k127_2680391_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 429.0
HKD2_k127_2680391_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 368.0
HKD2_k127_2680391_5 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 359.0
HKD2_k127_2680391_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 304.0
HKD2_k127_2680391_7 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 292.0
HKD2_k127_2680391_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 290.0
HKD2_k127_2680391_9 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000584 287.0
HKD2_k127_2690548_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 418.0
HKD2_k127_2690548_10 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00000000001016 66.0
HKD2_k127_2690548_11 Pyridoxamine 5'-phosphate oxidase - - - 0.00000001057 64.0
HKD2_k127_2690548_12 Limonene-1,2-epoxide hydrolase catalytic domain K06893 - - 0.0000006786 58.0
HKD2_k127_2690548_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124,K15734 - 1.1.1.105 0.000000000000000000000000000000000000000000000000000000000008005 217.0
HKD2_k127_2690548_4 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000601 219.0
HKD2_k127_2690548_5 TIGRFAM 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase K00004,K00008 - 1.1.1.14,1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000007204 188.0
HKD2_k127_2690548_6 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000003258 185.0
HKD2_k127_2690548_7 Lactoylglutathione lyase - - - 0.000000000000000000000000000006224 125.0
HKD2_k127_2690548_8 AMP binding - - - 0.00000000000000000000003571 104.0
HKD2_k127_2690548_9 Carbon starvation protein K06200 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000000000008049 69.0
HKD2_k127_2700811_0 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 3.845e-316 994.0
HKD2_k127_2700811_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.382e-272 846.0
HKD2_k127_2700811_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001201 240.0
HKD2_k127_2700811_3 Glycosyl transferase, family 2 - - - 0.0000000000000002887 90.0
HKD2_k127_2700811_4 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000002026 87.0
HKD2_k127_2704929_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 407.0
HKD2_k127_2704929_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 359.0
HKD2_k127_2704929_11 HEAT repeats - - - 0.000000001048 68.0
HKD2_k127_2704929_12 COG0477 Permeases of the major facilitator superfamily - - - 0.000000001964 62.0
HKD2_k127_2704929_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 325.0
HKD2_k127_2704929_3 Fatty acid hydroxylase superfamily K14424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 297.0
HKD2_k127_2704929_4 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005049 285.0
HKD2_k127_2704929_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
HKD2_k127_2704929_6 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000004232 235.0
HKD2_k127_2704929_7 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000008571 164.0
HKD2_k127_2704929_8 phosphoglycerate mutase family - - - 0.0000000000000000000000000000000006658 139.0
HKD2_k127_2704929_9 methyltransferase small - - - 0.000000000000000000000000000000001991 147.0
HKD2_k127_2775093_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.438e-215 682.0
HKD2_k127_2775093_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 4.585e-197 628.0
HKD2_k127_2775093_10 protein-disulfide reductase activity - - - 0.00000000000000000000000007625 113.0
HKD2_k127_2775093_11 MaoC like domain - - - 0.000000000000000171 83.0
HKD2_k127_2775093_12 Protein of unknown function (DUF1232) - - - 0.0000000005467 68.0
HKD2_k127_2775093_2 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 597.0
HKD2_k127_2775093_3 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 486.0
HKD2_k127_2775093_4 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 365.0
HKD2_k127_2775093_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004201 288.0
HKD2_k127_2775093_6 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002947 293.0
HKD2_k127_2775093_7 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
HKD2_k127_2775093_8 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000001321 214.0
HKD2_k127_2775093_9 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000001749 177.0
HKD2_k127_2822777_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.514e-244 771.0
HKD2_k127_2822777_1 SMART Elongator protein 3 MiaB NifB - - - 2.286e-233 753.0
HKD2_k127_2822777_10 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009521 277.0
HKD2_k127_2822777_11 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000136 124.0
HKD2_k127_2822777_12 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000001892 111.0
HKD2_k127_2822777_14 - - - - 0.0000000000000002211 82.0
HKD2_k127_2822777_15 Transcriptional regulator K07726 - - 0.00000000002089 68.0
HKD2_k127_2822777_16 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000006543 57.0
HKD2_k127_2822777_2 Domain of unknown function (DUF3552) K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 581.0
HKD2_k127_2822777_3 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 571.0
HKD2_k127_2822777_4 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 506.0
HKD2_k127_2822777_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 476.0
HKD2_k127_2822777_6 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 450.0
HKD2_k127_2822777_7 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 440.0
HKD2_k127_2822777_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 318.0
HKD2_k127_2822777_9 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 312.0
HKD2_k127_285150_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 449.0
HKD2_k127_285150_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 388.0
HKD2_k127_285150_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 318.0
HKD2_k127_285150_3 FES K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000007563 226.0
HKD2_k127_285150_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000001397 214.0
HKD2_k127_285150_5 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008360,GO:0008658,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000004081 91.0
HKD2_k127_285150_6 PFAM Conserved nitrate reductase-associated protein (Nitr_red_assoc) - - - 0.00000973 53.0
HKD2_k127_2903238_0 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 356.0
HKD2_k127_2903238_1 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 359.0
HKD2_k127_2903238_2 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 323.0
HKD2_k127_2903238_3 von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000001057 222.0
HKD2_k127_2903238_4 conserved protein (some members contain a von willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000001854 145.0
HKD2_k127_2903238_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K00652,K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47,6.3.3.3 0.0000000000000000000149 95.0
HKD2_k127_2927401_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 513.0
HKD2_k127_2927401_1 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 479.0
HKD2_k127_2927401_2 Protein export membrane protein K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 467.0
HKD2_k127_2927401_3 SecD/SecF GG Motif K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 306.0
HKD2_k127_2927401_4 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000004446 186.0
HKD2_k127_2927401_5 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000003279 177.0
HKD2_k127_2927401_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000006391 145.0
HKD2_k127_2927401_7 DNA excision K02806 - - 0.00007729 48.0
HKD2_k127_2930507_0 Acetyl propionyl-CoA carboxylase, alpha subunit - - - 3.558e-249 831.0
HKD2_k127_2930507_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000009039 201.0
HKD2_k127_2930507_2 Phosphopantetheine attachment site K02078 - - 0.0000000000000000002394 91.0
HKD2_k127_2930507_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 0.000000000000888 70.0
HKD2_k127_2930507_4 4'-phosphopantetheinyl transferase superfamily - - - 0.000000001077 69.0
HKD2_k127_2965493_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 474.0
HKD2_k127_2965493_1 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 321.0
HKD2_k127_2965493_2 glycosyl transferase group 1 K08256,K16150 - 2.4.1.11,2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
HKD2_k127_2965493_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000000000000000000000000000000000000000002127 234.0
HKD2_k127_2965493_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000479 223.0
HKD2_k127_2965493_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001939 220.0
HKD2_k127_2965493_6 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000001779 201.0
HKD2_k127_2982211_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 6.427e-208 668.0
HKD2_k127_2982211_1 COG1070 Sugar (pentulose and hexulose) kinases K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 620.0
HKD2_k127_2982211_2 FAD dependent oxidoreductase K00244,K16051 - 1.3.5.4,1.3.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 466.0
HKD2_k127_2982211_3 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 451.0
HKD2_k127_2982211_4 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007217 254.0
HKD2_k127_2982211_5 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000005278 186.0
HKD2_k127_2982211_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000002363 187.0
HKD2_k127_2982211_7 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000001923 90.0
HKD2_k127_304663_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 2.331e-278 895.0
HKD2_k127_304663_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 6.221e-275 878.0
HKD2_k127_304663_10 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000001349 134.0
HKD2_k127_304663_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000244 107.0
HKD2_k127_304663_12 - - - - 0.000000000000000000002283 95.0
HKD2_k127_304663_13 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000005219 91.0
HKD2_k127_304663_14 Predicted membrane protein (DUF2232) - - - 0.000000000000000005404 98.0
HKD2_k127_304663_15 Sh3 type 3 domain protein - - - 0.0000000000000001453 94.0
HKD2_k127_304663_16 PFAM amine oxidase - - - 0.000000000000002895 76.0
HKD2_k127_304663_17 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000001278 70.0
HKD2_k127_304663_18 - - - - 0.000001858 51.0
HKD2_k127_304663_19 HEAT repeats - - - 0.000003036 59.0
HKD2_k127_304663_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 414.0
HKD2_k127_304663_20 Outer membrane efflux protein K15725 - - 0.0001601 54.0
HKD2_k127_304663_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 343.0
HKD2_k127_304663_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000618 201.0
HKD2_k127_304663_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000005019 192.0
HKD2_k127_304663_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000005289 161.0
HKD2_k127_304663_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000002098 157.0
HKD2_k127_304663_8 Ribosomal protein L9, N-terminal domain K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000006548 143.0
HKD2_k127_304663_9 - - - - 0.00000000000000000000000000000000008081 134.0
HKD2_k127_3107956_0 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 9.186e-202 638.0
HKD2_k127_3107956_1 cytochrome P450 K20497 - 1.14.15.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 511.0
HKD2_k127_3107956_2 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 451.0
HKD2_k127_3107956_3 Ethanolamine ammonia-lyase light chain (EutC) K03736 - 4.3.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
HKD2_k127_3107956_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001661 237.0
HKD2_k127_3107956_5 Protein of unknown function (DUF3237) - - - 0.0000000000000000000001867 102.0
HKD2_k127_3107956_6 ThiS family - - - 0.000002392 52.0
HKD2_k127_3109257_0 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 452.0
HKD2_k127_3109257_1 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 385.0
HKD2_k127_3109257_2 Pfam:Transaldolase K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 390.0
HKD2_k127_3109257_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 319.0
HKD2_k127_3109257_4 N-acetyl-gamma-glutamyl-phosphate reductase activity K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
HKD2_k127_3109257_5 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000005907 209.0
HKD2_k127_3109257_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.0000000000000000000004136 98.0
HKD2_k127_3109257_7 Inward rectifier potassium channel K08715 - - 0.0000003215 55.0
HKD2_k127_3156868_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 605.0
HKD2_k127_3156868_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K14446 - 1.1.1.1,1.3.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 599.0
HKD2_k127_3156868_10 PFAM Acetoacetate decarboxylase - - - 0.00000000000000000000000000000000000000000000003848 181.0
HKD2_k127_3156868_11 Serine aminopeptidase, S33 K06889 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.000000000000000000000000000000000000000002858 172.0
HKD2_k127_3156868_12 Cytochrome c - - - 0.000000000000000000000000914 114.0
HKD2_k127_3156868_13 CBS domain containing protein K04767 - - 0.00000000000000000000999 98.0
HKD2_k127_3156868_14 Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000002848 87.0
HKD2_k127_3156868_15 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K10126 - - 0.000000000000006979 80.0
HKD2_k127_3156868_16 Cytochrome c K17222 - - 0.00000000000003709 79.0
HKD2_k127_3156868_17 Trypsin-like peptidase domain - - - 0.00000004069 65.0
HKD2_k127_3156868_18 DnaJ molecular chaperone homology domain - - - 0.00007612 53.0
HKD2_k127_3156868_19 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0005322 49.0
HKD2_k127_3156868_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 518.0
HKD2_k127_3156868_3 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 516.0
HKD2_k127_3156868_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 476.0
HKD2_k127_3156868_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 388.0
HKD2_k127_3156868_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 380.0
HKD2_k127_3156868_7 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000116 286.0
HKD2_k127_3156868_8 Diacylglycerol O-acyltransferase K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000006263 253.0
HKD2_k127_3156868_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000004014 228.0
HKD2_k127_3163489_0 ATP-dependent helicase K03579 - 3.6.4.13 1.61e-206 671.0
HKD2_k127_3163489_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.994e-203 644.0
HKD2_k127_3163489_10 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 382.0
HKD2_k127_3163489_11 ABC-type dipeptide transport system periplasmic component K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 368.0
HKD2_k127_3163489_12 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 339.0
HKD2_k127_3163489_13 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 319.0
HKD2_k127_3163489_14 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 321.0
HKD2_k127_3163489_15 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 308.0
HKD2_k127_3163489_16 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003263 280.0
HKD2_k127_3163489_17 nitrogen compound transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000016 259.0
HKD2_k127_3163489_18 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000002912 246.0
HKD2_k127_3163489_19 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000002543 228.0
HKD2_k127_3163489_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.614e-202 647.0
HKD2_k127_3163489_20 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000003562 207.0
HKD2_k127_3163489_21 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000002899 176.0
HKD2_k127_3163489_22 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000006596 169.0
HKD2_k127_3163489_23 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000000000001144 169.0
HKD2_k127_3163489_24 - - - - 0.000000000000000000000000000000000000005565 164.0
HKD2_k127_3163489_25 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000009528 134.0
HKD2_k127_3163489_26 COG0657 Esterase lipase - - - 0.0000000000000000000000000000006968 123.0
HKD2_k127_3163489_27 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000005362 120.0
HKD2_k127_3163489_28 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000434 109.0
HKD2_k127_3163489_29 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000719 109.0
HKD2_k127_3163489_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 606.0
HKD2_k127_3163489_30 Divergent 4Fe-4S mono-cluster K05337 - - 0.00000000000000000004112 91.0
HKD2_k127_3163489_31 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000008594 89.0
HKD2_k127_3163489_32 Ribosomal L32p protein family - - - 0.0000000000000000121 83.0
HKD2_k127_3163489_33 - - - - 0.0000000003247 70.0
HKD2_k127_3163489_34 protein trimerization K15368 - - 0.00001434 55.0
HKD2_k127_3163489_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 604.0
HKD2_k127_3163489_5 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 583.0
HKD2_k127_3163489_6 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 499.0
HKD2_k127_3163489_7 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 412.0
HKD2_k127_3163489_8 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 405.0
HKD2_k127_3163489_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 382.0
HKD2_k127_316471_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 7.606e-220 689.0
HKD2_k127_316471_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 528.0
HKD2_k127_316471_10 amine dehydrogenase activity K20276 - - 0.00000000000000003378 96.0
HKD2_k127_316471_11 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.0000000000000002713 88.0
HKD2_k127_316471_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 397.0
HKD2_k127_316471_3 CoA-transferase family III K07544 - 2.8.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 355.0
HKD2_k127_316471_4 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 315.0
HKD2_k127_316471_5 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005609 281.0
HKD2_k127_316471_6 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000000000000000000000000000000001078 239.0
HKD2_k127_316471_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000002006 216.0
HKD2_k127_316471_8 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000001309 199.0
HKD2_k127_316471_9 TPM domain K06872 - - 0.0000000000000000000000000000000005934 147.0
HKD2_k127_3178397_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1690.0
HKD2_k127_3178397_1 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1309.0
HKD2_k127_3178397_10 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 372.0
HKD2_k127_3178397_11 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 340.0
HKD2_k127_3178397_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 4.594e-231 724.0
HKD2_k127_3178397_3 Serine dehydratase K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 578.0
HKD2_k127_3178397_4 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 460.0
HKD2_k127_3178397_5 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 462.0
HKD2_k127_3178397_6 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 449.0
HKD2_k127_3178397_7 HlyD membrane-fusion protein of T1SS K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 450.0
HKD2_k127_3178397_8 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 448.0
HKD2_k127_3178397_9 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 414.0
HKD2_k127_3199142_0 alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 597.0
HKD2_k127_3199142_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 390.0
HKD2_k127_3199142_10 Type II secretion system protein K K02460 - - 0.000512 51.0
HKD2_k127_3199142_2 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 371.0
HKD2_k127_3199142_3 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 346.0
HKD2_k127_3199142_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 297.0
HKD2_k127_3199142_5 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000004249 215.0
HKD2_k127_3199142_6 Type IV pilus assembly protein PilM; K02461 - - 0.0000000000000000000000000000002725 139.0
HKD2_k127_3199142_7 Carboxylesterase family K03929 - - 0.0000000000000008412 79.0
HKD2_k127_3199142_8 Type II secretion system (T2SS), protein M K02462 - - 0.00001088 55.0
HKD2_k127_3199142_9 - - - - 0.00001809 57.0
HKD2_k127_3288901_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 366.0
HKD2_k127_3288901_1 PFAM DegT DnrJ EryC1 StrS aminotransferase family K20429 - 2.6.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 361.0
HKD2_k127_3288901_2 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 319.0
HKD2_k127_3288901_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008994 243.0
HKD2_k127_3288901_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000002486 151.0
HKD2_k127_3288901_5 radical SAM domain protein - - - 0.000000000000000000000000004852 122.0
HKD2_k127_3288901_6 light absorption K06893 - - 0.000000000000000000000001904 109.0
HKD2_k127_3288901_7 DSBA-like thioredoxin domain - - - 0.000000000000002772 91.0
HKD2_k127_3288901_8 - - - - 0.000000000001621 80.0
HKD2_k127_3288901_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000217 67.0
HKD2_k127_3307469_0 Carboxyl transferase domain - - - 2.651e-228 719.0
HKD2_k127_3307469_1 Acyclic terpene utilisation family protein AtuA - - - 1.491e-224 710.0
HKD2_k127_3307469_2 Biotin carboxylase C-terminal domain K01965,K01968 - 6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 585.0
HKD2_k127_3307469_3 PFAM acyl-CoA dehydrogenase domain protein K11731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 366.0
HKD2_k127_3307469_4 Mate efflux family protein K03327 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006767 287.0
HKD2_k127_3307469_5 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000001929 249.0
HKD2_k127_3307469_6 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000001956 224.0
HKD2_k127_3307469_7 enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000004022 225.0
HKD2_k127_3307469_8 Rhodanese Homology Domain - - - 0.00000000000000000000000000000001034 133.0
HKD2_k127_3307469_9 Cupin 2, conserved barrel domain protein - - - 0.0000421 53.0
HKD2_k127_3377067_0 NADH flavin oxidoreductase NADH oxidase K00317,K21833 - 1.5.8.1,1.5.8.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 601.0
HKD2_k127_3377067_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 474.0
HKD2_k127_3377067_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 395.0
HKD2_k127_3377067_3 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000001807 214.0
HKD2_k127_3377067_4 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000001008 153.0
HKD2_k127_3377067_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000253 128.0
HKD2_k127_3377067_6 electron transfer activity K03521 - - 0.00000000000000000001919 102.0
HKD2_k127_3377980_0 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 524.0
HKD2_k127_3377980_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 426.0
HKD2_k127_3377980_2 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 346.0
HKD2_k127_3377980_3 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 262.0
HKD2_k127_3377980_4 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000000000004901 111.0
HKD2_k127_3395550_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1836.0
HKD2_k127_3395550_1 PFAM Glycoside hydrolase 15-related - - - 0.0 1030.0
HKD2_k127_3395550_2 Glycosyl transferase family 21 K03669 - - 3.879e-239 779.0
HKD2_k127_3395550_3 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 529.0
HKD2_k127_3395550_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K18688 - 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 490.0
HKD2_k127_3395550_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 384.0
HKD2_k127_3395550_6 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 315.0
HKD2_k127_3395550_7 Protein of unknown function (DUF3131) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 314.0
HKD2_k127_34961_0 DNA topoisomerase K02470,K02622 - 5.99.1.3 5.478e-252 794.0
HKD2_k127_34961_1 topoisomerase K02469 - 5.99.1.3 6.451e-206 661.0
HKD2_k127_34961_2 PFAM CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 412.0
HKD2_k127_34961_3 Alpha beta hydrolase K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
HKD2_k127_34961_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 304.0
HKD2_k127_34961_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000003723 76.0
HKD2_k127_353899_0 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 605.0
HKD2_k127_353899_1 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 515.0
HKD2_k127_353899_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 447.0
HKD2_k127_353899_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 409.0
HKD2_k127_353899_4 neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 378.0
HKD2_k127_353899_5 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 373.0
HKD2_k127_353899_6 Beta-lactamase K08869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007089 269.0
HKD2_k127_353899_7 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.00000000000000000000000000007709 128.0
HKD2_k127_353899_8 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000007344 64.0
HKD2_k127_3540628_0 Glycosyl transferase family 21 - - - 1.007e-271 891.0
HKD2_k127_3540628_1 Thiamine pyrophosphate enzyme, central domain - - - 2.673e-234 736.0
HKD2_k127_3540628_10 membrane - - - 0.00000000000000000000000000000000000000000000003298 173.0
HKD2_k127_3540628_11 - - - - 0.000000000000000000000000000001095 124.0
HKD2_k127_3540628_12 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000004094 123.0
HKD2_k127_3540628_13 transferase activity, transferring glycosyl groups K00786 - - 0.0000000000002855 80.0
HKD2_k127_3540628_14 domain, Protein K20276 - - 0.00000000006344 68.0
HKD2_k127_3540628_15 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000695 46.0
HKD2_k127_3540628_16 AAA domain - - - 0.0001032 45.0
HKD2_k127_3540628_17 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096 2.7.7.59 0.0004334 54.0
HKD2_k127_3540628_2 alpha-L-arabinofuranosidase K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 605.0
HKD2_k127_3540628_3 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 567.0
HKD2_k127_3540628_4 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 414.0
HKD2_k127_3540628_5 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 334.0
HKD2_k127_3540628_6 Belongs to the glycosyl hydrolase 26 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 368.0
HKD2_k127_3540628_7 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 301.0
HKD2_k127_3540628_8 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000005854 233.0
HKD2_k127_3540628_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000003243 217.0
HKD2_k127_3671788_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.55e-293 912.0
HKD2_k127_3671788_1 Belongs to the heat shock protein 70 family - - - 5.112e-250 801.0
HKD2_k127_3671788_10 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074,K17735 - 1.1.1.108,1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000003423 231.0
HKD2_k127_3671788_11 PFAM short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000006626 225.0
HKD2_k127_3671788_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000000001013 155.0
HKD2_k127_3671788_13 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000416 169.0
HKD2_k127_3671788_14 - - - - 0.0000000000000000000000000000000000002425 142.0
HKD2_k127_3671788_15 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000000004755 149.0
HKD2_k127_3671788_16 translation release factor activity - - - 0.000000000000000000000000000000005493 134.0
HKD2_k127_3671788_17 Enoyl-(Acyl carrier protein) reductase K07535 - - 0.000000000000000000000000000005079 129.0
HKD2_k127_3671788_18 - - - - 0.00001961 53.0
HKD2_k127_3671788_2 Heat shock protein 70 family - - - 1.524e-199 660.0
HKD2_k127_3671788_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 4.661e-198 627.0
HKD2_k127_3671788_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 524.0
HKD2_k127_3671788_5 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 477.0
HKD2_k127_3671788_6 Ribonuclease E/G family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 469.0
HKD2_k127_3671788_7 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 389.0
HKD2_k127_3671788_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 387.0
HKD2_k127_3671788_9 PFAM ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 320.0
HKD2_k127_3746267_0 Curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 314.0
HKD2_k127_3746267_1 (Lipo)protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003761 238.0
HKD2_k127_3746267_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000001528 186.0
HKD2_k127_3746267_3 PFAM Enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000001093 143.0
HKD2_k127_3746267_4 Lipoprotein - - - 0.000000000000000000000000000000005722 132.0
HKD2_k127_3746267_5 Protein of unknown function (DUF433) - - - 0.0000000000000000001378 93.0
HKD2_k127_3746267_6 Mut7-C RNAse domain - - - 0.0000000000737 66.0
HKD2_k127_3816360_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9.353e-304 947.0
HKD2_k127_3816360_1 Protein of unknown function (DUF3604) - - - 3.145e-231 741.0
HKD2_k127_3816360_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 339.0
HKD2_k127_3816360_11 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000004147 244.0
HKD2_k127_3816360_12 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000002855 230.0
HKD2_k127_3816360_13 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.0000000000000000000000000000000000000000000000000000000000002154 222.0
HKD2_k127_3816360_14 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000009183 224.0
HKD2_k127_3816360_15 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000001181 223.0
HKD2_k127_3816360_16 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000000001327 207.0
HKD2_k127_3816360_17 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000000000000001034 183.0
HKD2_k127_3816360_18 KR domain K07124 - - 0.000000000000000000000000000000000000000000009116 178.0
HKD2_k127_3816360_19 SnoaL-like domain - - - 0.0000000000000000000000000000000000000001153 155.0
HKD2_k127_3816360_2 PFAM AMP-dependent synthetase and ligase K00666 - - 3.656e-195 625.0
HKD2_k127_3816360_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000008813 128.0
HKD2_k127_3816360_21 CBS domain - - - 0.0000000000000000000000004782 114.0
HKD2_k127_3816360_22 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.000000000000000000005859 101.0
HKD2_k127_3816360_23 Peptidase M1 membrane alanine aminopeptidase - - - 0.0000000000000001028 95.0
HKD2_k127_3816360_24 PPIC-type PPIASE domain - - - 0.000000000000004783 87.0
HKD2_k127_3816360_25 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000002093 80.0
HKD2_k127_3816360_27 PFAM Family of - - - 0.0001913 55.0
HKD2_k127_3816360_28 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 0.0003044 54.0
HKD2_k127_3816360_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897,K02182,K22133 - 6.2.1.3,6.2.1.48,6.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 553.0
HKD2_k127_3816360_4 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 489.0
HKD2_k127_3816360_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 409.0
HKD2_k127_3816360_6 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 391.0
HKD2_k127_3816360_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 348.0
HKD2_k127_3816360_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 367.0
HKD2_k127_3816360_9 HI0933-like protein K00313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 343.0
HKD2_k127_3871131_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.976e-279 878.0
HKD2_k127_3871131_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.965e-212 696.0
HKD2_k127_3871131_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 344.0
HKD2_k127_3871131_11 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 330.0
HKD2_k127_3871131_12 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 329.0
HKD2_k127_3871131_13 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 329.0
HKD2_k127_3871131_14 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 305.0
HKD2_k127_3871131_15 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 297.0
HKD2_k127_3871131_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002258 302.0
HKD2_k127_3871131_17 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000002088 244.0
HKD2_k127_3871131_18 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000001645 183.0
HKD2_k127_3871131_19 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000883 173.0
HKD2_k127_3871131_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 536.0
HKD2_k127_3871131_20 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000318 171.0
HKD2_k127_3871131_21 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000000002436 134.0
HKD2_k127_3871131_22 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000005464 123.0
HKD2_k127_3871131_23 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.000000000000000000000000004843 115.0
HKD2_k127_3871131_24 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000006294 94.0
HKD2_k127_3871131_25 Essential cell division protein K03589 - - 0.00000000000000000008847 101.0
HKD2_k127_3871131_26 AAA domain - - - 0.00000000000007295 79.0
HKD2_k127_3871131_27 - - - - 0.0000000000009757 80.0
HKD2_k127_3871131_28 - - - - 0.000000000008904 77.0
HKD2_k127_3871131_29 - - - - 0.0000000004208 72.0
HKD2_k127_3871131_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 505.0
HKD2_k127_3871131_30 PFAM Colicin V production protein K03558 - - 0.000009185 54.0
HKD2_k127_3871131_33 - - - - 0.0005888 47.0
HKD2_k127_3871131_34 PFAM magnesium chelatase ChlI subunit K07391 - - 0.0006215 44.0
HKD2_k127_3871131_4 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 485.0
HKD2_k127_3871131_5 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 494.0
HKD2_k127_3871131_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 467.0
HKD2_k127_3871131_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 459.0
HKD2_k127_3871131_8 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 444.0
HKD2_k127_3871131_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008351 404.0
HKD2_k127_38782_0 formate C-acetyltransferase glycine radical - - - 0.0 1211.0
HKD2_k127_38782_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 339.0
HKD2_k127_38782_2 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
HKD2_k127_38782_3 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000002685 217.0
HKD2_k127_38782_4 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.000000000003251 68.0
HKD2_k127_3879514_0 Pfam:CPSase_L_chain - - - 0.0 1062.0
HKD2_k127_3879514_1 Carboxyl transferase domain - - - 1.022e-257 810.0
HKD2_k127_3879514_10 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000000000001681 175.0
HKD2_k127_3879514_11 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000000000005361 154.0
HKD2_k127_3879514_12 SnoaL-like domain - - - 0.00000000000000000000000000000000008049 141.0
HKD2_k127_3879514_13 Glycosyl transferases group 1 - - - 0.00000000000000000000002393 108.0
HKD2_k127_3879514_14 SdrD B-like domain - - - 0.000000000009416 78.0
HKD2_k127_3879514_15 antibiotic catabolic process K18235 - - 0.0000754 52.0
HKD2_k127_3879514_16 zinc-ribbon domain - - - 0.0001854 49.0
HKD2_k127_3879514_2 - K20614 - 4.2.1.127,5.4.4.4 1.332e-205 664.0
HKD2_k127_3879514_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 349.0
HKD2_k127_3879514_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 333.0
HKD2_k127_3879514_5 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 339.0
HKD2_k127_3879514_6 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 314.0
HKD2_k127_3879514_7 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002034 265.0
HKD2_k127_3879514_8 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002513 266.0
HKD2_k127_3879514_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000009322 176.0
HKD2_k127_3889688_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 3529.0
HKD2_k127_3889688_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 389.0
HKD2_k127_3889688_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000003427 203.0
HKD2_k127_3889688_3 PAS fold - - - 0.0000000000000000000000000000000000000000002377 173.0
HKD2_k127_3889688_4 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000008406 142.0
HKD2_k127_3889688_5 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000008364 101.0
HKD2_k127_3889688_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - 0.00000000000001022 83.0
HKD2_k127_3889688_7 Phage integrase family - - - 0.0003215 45.0
HKD2_k127_3905540_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1449.0
HKD2_k127_3905540_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1315.0
HKD2_k127_3905540_10 Shikimate kinase K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000001874 217.0
HKD2_k127_3905540_11 fimbrial biogenesis protein PilN K02663 - - 0.00000000000000000000000000000000000000000000000000000000002783 212.0
HKD2_k127_3905540_12 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000005488 143.0
HKD2_k127_3905540_13 Belongs to the frataxin K06202 - - 0.0000000000000000000000000000000000131 138.0
HKD2_k127_3905540_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 3.209e-316 985.0
HKD2_k127_3905540_3 Type 4 fimbrial biogenesis protein K02666 - - 1.681e-248 785.0
HKD2_k127_3905540_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 518.0
HKD2_k127_3905540_5 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 481.0
HKD2_k127_3905540_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 443.0
HKD2_k127_3905540_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 323.0
HKD2_k127_3905540_8 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 287.0
HKD2_k127_3905540_9 Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000148 270.0
HKD2_k127_3956972_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 439.0
HKD2_k127_3956972_1 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 411.0
HKD2_k127_3956972_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 295.0
HKD2_k127_3956972_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000001428 234.0
HKD2_k127_3956972_4 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000002782 197.0
HKD2_k127_3956972_5 endonuclease containing a URI domain K07461 - - 0.00000000000000001043 85.0
HKD2_k127_3956972_6 GIY-YIG catalytic domain K07461 - - 0.000007184 57.0
HKD2_k127_3964996_0 Malic enzyme, NAD binding domain K00027,K00029,K22212 GO:0000166,GO:0003674,GO:0003824,GO:0004470,GO:0004471,GO:0004473,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006108,GO:0006113,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016051,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0019752,GO:0030145,GO:0032787,GO:0036094,GO:0043167,GO:0043169,GO:0043436,GO:0043464,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.38,1.1.1.40,4.1.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 538.0
HKD2_k127_3964996_1 Aldo/keto reductase family K00064 - 1.1.1.122 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 367.0
HKD2_k127_3964996_2 Mandelate Racemase Muconate Lactonizing K01684,K18334 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0050023,GO:0071704,GO:1901575 4.2.1.6,4.2.1.68 0.00000000000000000000000000000000000001117 145.0
HKD2_k127_3964996_3 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000001688 131.0
HKD2_k127_3964996_4 GYD domain - - - 0.0000000000000000000000000002965 116.0
HKD2_k127_4002040_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.018e-229 731.0
HKD2_k127_4002040_1 AAA ATPase domain K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 546.0
HKD2_k127_4002040_10 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 314.0
HKD2_k127_4002040_11 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 293.0
HKD2_k127_4002040_12 COG0788 Formyltetrahydrofolate hydrolase K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001105 280.0
HKD2_k127_4002040_13 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000009387 263.0
HKD2_k127_4002040_14 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 263.0
HKD2_k127_4002040_15 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000008661 243.0
HKD2_k127_4002040_16 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000009165 239.0
HKD2_k127_4002040_17 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000002813 221.0
HKD2_k127_4002040_18 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000003333 211.0
HKD2_k127_4002040_19 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000124 190.0
HKD2_k127_4002040_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 535.0
HKD2_k127_4002040_20 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000007022 183.0
HKD2_k127_4002040_21 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000008026 178.0
HKD2_k127_4002040_22 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000004031 164.0
HKD2_k127_4002040_23 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000007222 150.0
HKD2_k127_4002040_24 response regulator - - - 0.00000000000000000000000000000000000001582 163.0
HKD2_k127_4002040_25 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000001229 126.0
HKD2_k127_4002040_26 COG1145 Ferredoxin - - - 0.0000000000000000000005013 106.0
HKD2_k127_4002040_27 Domain of unknown function (DUF1844) - - - 0.00000000000000000003025 96.0
HKD2_k127_4002040_28 Involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose required for a number of critical mannosyl transfer reactions K17497 GO:0003674,GO:0003824,GO:0004615,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006486,GO:0006487,GO:0006605,GO:0006807,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010494,GO:0015031,GO:0015833,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019538,GO:0031012,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034645,GO:0035770,GO:0036211,GO:0036464,GO:0042886,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0062039,GO:0062040,GO:0070085,GO:0070727,GO:0070972,GO:0071702,GO:0071704,GO:0071705,GO:0072594,GO:0072599,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.4.2.8 0.0000000000000000002451 99.0
HKD2_k127_4002040_29 Universal stress protein K06149 - - 0.0000000000000000004286 93.0
HKD2_k127_4002040_3 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 511.0
HKD2_k127_4002040_30 - - - - 0.00000000000136 70.0
HKD2_k127_4002040_31 - - - - 0.000002501 53.0
HKD2_k127_4002040_32 Tetratricopeptide repeat - - - 0.00002808 55.0
HKD2_k127_4002040_33 Sulfurtransferase TusA K04085 - - 0.0001109 53.0
HKD2_k127_4002040_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 489.0
HKD2_k127_4002040_5 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 446.0
HKD2_k127_4002040_6 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 371.0
HKD2_k127_4002040_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 352.0
HKD2_k127_4002040_8 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 329.0
HKD2_k127_4002040_9 Protein of unknown function (DUF3987) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 324.0
HKD2_k127_4006279_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1075.0
HKD2_k127_4006279_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.859e-295 927.0
HKD2_k127_4006279_10 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 393.0
HKD2_k127_4006279_11 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 354.0
HKD2_k127_4006279_12 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 321.0
HKD2_k127_4006279_13 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 312.0
HKD2_k127_4006279_14 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 320.0
HKD2_k127_4006279_15 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002339 271.0
HKD2_k127_4006279_16 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000002306 244.0
HKD2_k127_4006279_17 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000001825 230.0
HKD2_k127_4006279_18 O-methyltransferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000005812 220.0
HKD2_k127_4006279_19 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000006175 204.0
HKD2_k127_4006279_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.896e-281 897.0
HKD2_k127_4006279_20 KR domain K07124 - - 0.00000000000000000000000000000000000000000004058 178.0
HKD2_k127_4006279_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000005767 138.0
HKD2_k127_4006279_22 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000009254 136.0
HKD2_k127_4006279_23 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000004563 130.0
HKD2_k127_4006279_24 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000002239 120.0
HKD2_k127_4006279_25 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000244 91.0
HKD2_k127_4006279_26 Lysine methyltransferase - - - 0.000000000000000006942 92.0
HKD2_k127_4006279_27 MAATS-type transcriptional repressor, C-terminal region K03577 - - 0.000000000000001434 85.0
HKD2_k127_4006279_28 SMART Tetratricopeptide - - - 0.00000000000009792 83.0
HKD2_k127_4006279_29 Modulates RecA activity K03565 - - 0.00000001691 63.0
HKD2_k127_4006279_3 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 524.0
HKD2_k127_4006279_31 PFAM S-layer homology domain - - - 0.0000892 53.0
HKD2_k127_4006279_4 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 524.0
HKD2_k127_4006279_5 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 473.0
HKD2_k127_4006279_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 462.0
HKD2_k127_4006279_7 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 429.0
HKD2_k127_4006279_8 AAA domain K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 424.0
HKD2_k127_4006279_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 420.0
HKD2_k127_4058875_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 445.0
HKD2_k127_4058875_1 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 397.0
HKD2_k127_4058875_10 Diacylglycerol O-acyltransferase K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000000196 209.0
HKD2_k127_4058875_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000003864 162.0
HKD2_k127_4058875_12 cheY-homologous receiver domain - - - 0.00000000000000000000000000003905 121.0
HKD2_k127_4058875_13 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000008777 108.0
HKD2_k127_4058875_14 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000001939 105.0
HKD2_k127_4058875_15 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000009346 93.0
HKD2_k127_4058875_16 thiolester hydrolase activity K06889 - - 0.000000000000003438 78.0
HKD2_k127_4058875_17 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.000000000001683 76.0
HKD2_k127_4058875_18 PFAM Glycosyl transferase, group 1 - - - 0.000002439 51.0
HKD2_k127_4058875_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 404.0
HKD2_k127_4058875_3 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 389.0
HKD2_k127_4058875_4 Haloacid dehalogenase domain protein hydrolase, type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 342.0
HKD2_k127_4058875_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 279.0
HKD2_k127_4058875_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001052 275.0
HKD2_k127_4058875_7 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000002067 230.0
HKD2_k127_4058875_8 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000000000000003304 209.0
HKD2_k127_4058875_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000007524 201.0
HKD2_k127_4063167_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1236.0
HKD2_k127_4063167_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5e-324 1014.0
HKD2_k127_4063167_10 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000001479 223.0
HKD2_k127_4063167_11 Transcriptional regulator - - - 0.0000000000000000000000000000000001176 139.0
HKD2_k127_4063167_12 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000001987 108.0
HKD2_k127_4063167_13 PFAM heat shock protein DnaJ K04082 - - 0.0000000000000000000000005411 115.0
HKD2_k127_4063167_14 iron-sulfur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000002475 95.0
HKD2_k127_4063167_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 598.0
HKD2_k127_4063167_3 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 557.0
HKD2_k127_4063167_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 385.0
HKD2_k127_4063167_5 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 363.0
HKD2_k127_4063167_6 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 325.0
HKD2_k127_4063167_7 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 326.0
HKD2_k127_4063167_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 312.0
HKD2_k127_4063167_9 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009952 287.0
HKD2_k127_4065384_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 449.0
HKD2_k127_4065384_1 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 338.0
HKD2_k127_4065384_2 Glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 325.0
HKD2_k127_4135392_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 419.0
HKD2_k127_4135392_1 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 382.0
HKD2_k127_4135392_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 332.0
HKD2_k127_4135392_3 Acid phosphatase homologues K09474 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
HKD2_k127_4135392_4 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004387 287.0
HKD2_k127_4135392_5 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002844 277.0
HKD2_k127_4135392_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000006178 166.0
HKD2_k127_4135392_7 Domain of unknown function (DUF4381) - - - 0.00000000000000000000002393 108.0
HKD2_k127_4135392_8 cell adhesion K02650,K02682 - - 0.0000000000007567 74.0
HKD2_k127_4135392_9 Oxygen tolerance - - - 0.000000000009096 76.0
HKD2_k127_4139782_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1028.0
HKD2_k127_4139782_1 elongation factor Tu domain 2 protein K02355 - - 2.356e-236 749.0
HKD2_k127_4139782_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 313.0
HKD2_k127_4139782_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 304.0
HKD2_k127_4139782_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003187 289.0
HKD2_k127_4139782_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000003595 226.0
HKD2_k127_4139782_6 epimerase dehydratase K07071 - - 0.000000000000000000000000000000000000000000000000005098 187.0
HKD2_k127_4139782_7 helix_turn_helix, mercury resistance K22491 - - 0.0000000000000000000000000000000000000001055 163.0
HKD2_k127_4139782_8 - - - - 0.000000000000000001006 99.0
HKD2_k127_4139782_9 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.0000000001517 72.0
HKD2_k127_4147918_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 6.165e-298 939.0
HKD2_k127_4147918_1 Bacterial protein of unknown function (DUF853) - - - 3.865e-210 663.0
HKD2_k127_4147918_10 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000579 138.0
HKD2_k127_4147918_11 - - - - 0.000000000000000000000000000000836 130.0
HKD2_k127_4147918_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000005336 100.0
HKD2_k127_4147918_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 537.0
HKD2_k127_4147918_3 Peptidase dimerisation domain K01439,K13049 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 514.0
HKD2_k127_4147918_4 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 351.0
HKD2_k127_4147918_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 355.0
HKD2_k127_4147918_6 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 323.0
HKD2_k127_4147918_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001457 269.0
HKD2_k127_4147918_8 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000001691 179.0
HKD2_k127_4147918_9 stress protein (general stress protein 26) - - - 0.00000000000000000000000000000000000000001084 168.0
HKD2_k127_4164741_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000002006 261.0
HKD2_k127_4164741_1 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001161 275.0
HKD2_k127_4164741_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000003587 182.0
HKD2_k127_4164741_3 HNH nucleases - - - 0.0000000000000000000000000000000000003742 151.0
HKD2_k127_4164741_4 beta-galactosidase activity - - - 0.0000000000001025 85.0
HKD2_k127_4164741_5 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 0.00000000009266 76.0
HKD2_k127_4203274_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.808e-237 760.0
HKD2_k127_4203274_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 4.606e-222 718.0
HKD2_k127_4203274_10 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000005852 186.0
HKD2_k127_4203274_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000003716 180.0
HKD2_k127_4203274_12 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.00000000000000000000001061 103.0
HKD2_k127_4203274_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000007746 100.0
HKD2_k127_4203274_14 Peroxiredoxin K03564 - 1.11.1.15 0.00001017 47.0
HKD2_k127_4203274_2 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 561.0
HKD2_k127_4203274_3 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 422.0
HKD2_k127_4203274_4 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 338.0
HKD2_k127_4203274_5 TIGRFAM tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001947 284.0
HKD2_k127_4203274_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000002379 271.0
HKD2_k127_4203274_7 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000005772 261.0
HKD2_k127_4203274_8 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000055 237.0
HKD2_k127_4203274_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000005487 228.0
HKD2_k127_4256570_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K00483,K21726 - 1.14.13.166,1.14.13.29,1.14.14.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 602.0
HKD2_k127_4256570_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 501.0
HKD2_k127_4256570_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004592 267.0
HKD2_k127_4256570_11 COG0695 glutaredoxin and related proteins - - - 0.000000000000000000000000000000000000000000000000000000001177 209.0
HKD2_k127_4256570_12 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000002816 205.0
HKD2_k127_4256570_13 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000003352 187.0
HKD2_k127_4256570_14 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000002405 179.0
HKD2_k127_4256570_15 EVE domain - - - 0.00000000000000000000000000000000000001094 148.0
HKD2_k127_4256570_17 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000008638 70.0
HKD2_k127_4256570_2 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 405.0
HKD2_k127_4256570_3 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 394.0
HKD2_k127_4256570_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 347.0
HKD2_k127_4256570_5 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 334.0
HKD2_k127_4256570_6 dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 312.0
HKD2_k127_4256570_7 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 288.0
HKD2_k127_4256570_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002898 284.0
HKD2_k127_4256570_9 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
HKD2_k127_4313433_0 DNA polymerase type-B family K02336 - 2.7.7.7 5.728e-267 845.0
HKD2_k127_4313433_1 Alkaline phosphatase K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 528.0
HKD2_k127_4313433_10 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001185 248.0
HKD2_k127_4313433_11 Transcriptional regulator, CarD family K07736 - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
HKD2_k127_4313433_12 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000001699 193.0
HKD2_k127_4313433_13 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000004592 150.0
HKD2_k127_4313433_14 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000000000000000006896 155.0
HKD2_k127_4313433_15 (Rieske (2Fe-2S) domain) K00363,K05710 - 1.7.1.15 0.00000000000000000000000001152 111.0
HKD2_k127_4313433_16 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000001919 113.0
HKD2_k127_4313433_17 Major Facilitator Superfamily - - - 0.000000000000000000000000377 119.0
HKD2_k127_4313433_18 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000006126 114.0
HKD2_k127_4313433_19 Belongs to the frataxin family K06202,K19054 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 1.16.3.1 0.00000000000000001459 86.0
HKD2_k127_4313433_2 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 482.0
HKD2_k127_4313433_20 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.000002119 53.0
HKD2_k127_4313433_21 domain, Protein K00703,K07082 - 2.4.1.21 0.000002392 52.0
HKD2_k127_4313433_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 419.0
HKD2_k127_4313433_4 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 399.0
HKD2_k127_4313433_5 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 376.0
HKD2_k127_4313433_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 299.0
HKD2_k127_4313433_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 300.0
HKD2_k127_4313433_8 PFAM asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004978 293.0
HKD2_k127_4313433_9 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001385 280.0
HKD2_k127_4372194_0 RNA secondary structure unwinding K03724 - - 0.0 1509.0
HKD2_k127_4372194_1 GAF domain K12266 - - 1.309e-202 645.0
HKD2_k127_4372194_2 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 518.0
HKD2_k127_4372194_3 related to 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 414.0
HKD2_k127_4372194_4 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000004057 211.0
HKD2_k127_4372194_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000001301 196.0
HKD2_k127_4372194_6 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00002207 51.0
HKD2_k127_4372194_7 ZF-HD protein dimerisation region - - - 0.0003134 46.0
HKD2_k127_460121_0 Acyl transferase domain - - - 0.0 1987.0
HKD2_k127_460121_1 TRCF K03723 - - 9.702e-296 956.0
HKD2_k127_460121_10 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000012 295.0
HKD2_k127_460121_11 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005793 281.0
HKD2_k127_460121_12 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000002771 243.0
HKD2_k127_460121_13 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000005158 199.0
HKD2_k127_460121_14 PPIC-type PPIASE domain K02597,K03769,K03771 - 5.2.1.8 0.0000000000000000000000000000000000005715 152.0
HKD2_k127_460121_15 Tetratricopeptide repeat - - - 0.00000000000000008317 85.0
HKD2_k127_460121_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 7.752e-242 760.0
HKD2_k127_460121_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.643e-236 750.0
HKD2_k127_460121_4 alpha-glucan phosphorylase K00688 - 2.4.1.1 3.42e-233 741.0
HKD2_k127_460121_5 AMP-binding enzyme C-terminal domain K00666 - - 2.141e-194 624.0
HKD2_k127_460121_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 554.0
HKD2_k127_460121_7 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00973,K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 379.0
HKD2_k127_460121_8 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 354.0
HKD2_k127_460121_9 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 331.0
HKD2_k127_4622377_0 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 376.0
HKD2_k127_4622377_1 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000005331 230.0
HKD2_k127_4622377_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000006954 233.0
HKD2_k127_4622377_3 lactoylglutathione lyase activity K08234 - - 0.000000000000000000000000000000000000000000000003328 178.0
HKD2_k127_4622377_4 Ferredoxin K02230 - 6.6.1.2 0.0000000000000000000000000000000000000000000001837 171.0
HKD2_k127_4622377_5 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000001752 167.0
HKD2_k127_4622377_6 Parallel beta-helix repeats - - - 0.00000000000002644 76.0
HKD2_k127_466900_0 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 3.903e-197 624.0
HKD2_k127_466900_1 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 578.0
HKD2_k127_466900_10 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000007661 188.0
HKD2_k127_466900_11 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000319 186.0
HKD2_k127_466900_12 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000001081 188.0
HKD2_k127_466900_13 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000001912 181.0
HKD2_k127_466900_14 CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000009765 184.0
HKD2_k127_466900_15 FAD binding domain K00103 - 1.1.3.8 0.0000000000000000000000000000000000000000000537 168.0
HKD2_k127_466900_16 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000004102 160.0
HKD2_k127_466900_17 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.0000000000000000000000000000000000001043 160.0
HKD2_k127_466900_18 - - - - 0.000000000000000000000000000003637 123.0
HKD2_k127_466900_19 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000004342 115.0
HKD2_k127_466900_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 480.0
HKD2_k127_466900_20 Cytochrome c - - - 0.000000000000000000000000374 110.0
HKD2_k127_466900_21 NnrU protein - - - 0.0000000000000000000001692 106.0
HKD2_k127_466900_22 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000008595 108.0
HKD2_k127_466900_23 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000005904 77.0
HKD2_k127_466900_24 - - - - 0.00000000002955 69.0
HKD2_k127_466900_25 Phosphate acyltransferases - - - 0.00004956 48.0
HKD2_k127_466900_26 - - - - 0.0001057 53.0
HKD2_k127_466900_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 392.0
HKD2_k127_466900_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 376.0
HKD2_k127_466900_5 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 362.0
HKD2_k127_466900_6 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 341.0
HKD2_k127_466900_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 325.0
HKD2_k127_466900_8 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 308.0
HKD2_k127_466900_9 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000135 273.0
HKD2_k127_4753851_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.607e-202 636.0
HKD2_k127_4753851_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 545.0
HKD2_k127_4753851_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 433.0
HKD2_k127_4753851_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 309.0
HKD2_k127_4753851_4 serine-type endopeptidase activity K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 303.0
HKD2_k127_4753851_5 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004824 238.0
HKD2_k127_4753851_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000001657 220.0
HKD2_k127_4753851_7 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000001139 220.0
HKD2_k127_4753851_8 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000267 121.0
HKD2_k127_4753851_9 Protein of unknown function (DUF4242) - - - 0.0000000000000008044 83.0
HKD2_k127_4756747_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 4.789e-197 634.0
HKD2_k127_4756747_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 581.0
HKD2_k127_4756747_10 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000001832 240.0
HKD2_k127_4756747_11 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000009158 156.0
HKD2_k127_4756747_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000001044 157.0
HKD2_k127_4756747_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000006399 134.0
HKD2_k127_4756747_14 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000000004166 121.0
HKD2_k127_4756747_15 PFAM Cold-shock protein DNA-binding K03704 - - 0.00000000000000000000000003163 108.0
HKD2_k127_4756747_16 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000000141 102.0
HKD2_k127_4756747_17 Carboxyl transferase domain K13932 - 4.1.1.87 0.000000000000000008971 97.0
HKD2_k127_4756747_18 OstA-like protein K09774 - - 0.000000000000000009281 91.0
HKD2_k127_4756747_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 571.0
HKD2_k127_4756747_20 Protein of unknown function (DUF507) - - - 0.0000000000004358 72.0
HKD2_k127_4756747_21 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000546 63.0
HKD2_k127_4756747_22 Protein of unknown function (DUF507) - - - 0.000002458 54.0
HKD2_k127_4756747_23 protein transport across the cell outer membrane K02246,K08084 - - 0.0008754 49.0
HKD2_k127_4756747_3 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 480.0
HKD2_k127_4756747_4 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 383.0
HKD2_k127_4756747_5 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 333.0
HKD2_k127_4756747_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 319.0
HKD2_k127_4756747_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 268.0
HKD2_k127_4756747_8 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005297 269.0
HKD2_k127_4756747_9 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 264.0
HKD2_k127_493228_0 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000002091 192.0
HKD2_k127_493228_1 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000347 186.0
HKD2_k127_493228_2 tetratricopeptide repeat - - - 0.00000000000000000000001219 111.0
HKD2_k127_493228_3 Phospholipid methyltransferase - - - 0.00000000000000000008979 93.0
HKD2_k127_493228_4 Tetratricopeptide repeat - - - 0.0004168 51.0
HKD2_k127_5030421_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 548.0
HKD2_k127_5030421_1 Adventurous gliding motility protein R - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 299.0
HKD2_k127_5030421_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000004388 173.0
HKD2_k127_5030421_3 MaoC domain-containing protein dehydratase - - - 0.0000000001049 66.0
HKD2_k127_5114812_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 1.401e-312 978.0
HKD2_k127_5114812_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 580.0
HKD2_k127_5114812_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000002414 94.0
HKD2_k127_5114812_11 - K07283 - - 0.000000000002539 78.0
HKD2_k127_5114812_12 Domain of Unknown Function (DUF748) - - - 0.000000007968 69.0
HKD2_k127_5114812_13 protein involved in outer membrane biogenesis K07289 - - 0.000755 53.0
HKD2_k127_5114812_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 363.0
HKD2_k127_5114812_3 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000004131 241.0
HKD2_k127_5114812_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000008491 241.0
HKD2_k127_5114812_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000000005305 194.0
HKD2_k127_5114812_6 amino acid transport K02030 - - 0.00000000000000000000000000000000000000000000000000005846 198.0
HKD2_k127_5114812_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000005527 190.0
HKD2_k127_5114812_8 - - - - 0.00000000000000000000000000000000000000001654 173.0
HKD2_k127_5114812_9 F420-dependent - - - 0.00000000000000000000000000000000001235 148.0
HKD2_k127_5136027_0 6-phosphofructokinase activity K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 526.0
HKD2_k127_5136027_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 361.0
HKD2_k127_5136027_2 ATPase associated with various cellular activities AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 355.0
HKD2_k127_5136027_3 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002007 276.0
HKD2_k127_5136027_4 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001491 257.0
HKD2_k127_5136027_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.0000000000000000001065 101.0
HKD2_k127_5136027_6 'Cold-shock' DNA-binding domain - - - 0.0000139 52.0
HKD2_k127_5152791_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1249.0
HKD2_k127_5152791_1 Protein of unknown function (DUF3604) - - - 0.0 1072.0
HKD2_k127_5152791_10 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 496.0
HKD2_k127_5152791_11 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 496.0
HKD2_k127_5152791_12 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 494.0
HKD2_k127_5152791_13 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 438.0
HKD2_k127_5152791_14 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 441.0
HKD2_k127_5152791_15 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 415.0
HKD2_k127_5152791_16 ATPases associated with a variety of cellular activities K05833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 390.0
HKD2_k127_5152791_17 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 390.0
HKD2_k127_5152791_18 Belongs to the binding-protein-dependent transport system permease family K05832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 396.0
HKD2_k127_5152791_19 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 395.0
HKD2_k127_5152791_2 arylsulfatase A K01130 - 3.1.6.1 1.425e-285 882.0
HKD2_k127_5152791_20 Bacterial regulatory protein, Fis family K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 365.0
HKD2_k127_5152791_21 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 354.0
HKD2_k127_5152791_22 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 331.0
HKD2_k127_5152791_23 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 334.0
HKD2_k127_5152791_24 antisigma factor binding K04749,K04757 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 316.0
HKD2_k127_5152791_25 ABC transporter substrate binding protein K01989,K05832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000292 304.0
HKD2_k127_5152791_26 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005467 267.0
HKD2_k127_5152791_27 Methyl-viologen-reducing hydrogenase, delta subunit K02572,K02573,K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006603 269.0
HKD2_k127_5152791_28 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007895 247.0
HKD2_k127_5152791_29 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000004866 241.0
HKD2_k127_5152791_3 Cytochrome C and Quinol oxidase polypeptide I - - - 1.254e-276 859.0
HKD2_k127_5152791_30 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000002821 247.0
HKD2_k127_5152791_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000002482 216.0
HKD2_k127_5152791_32 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000008239 203.0
HKD2_k127_5152791_33 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000003121 202.0
HKD2_k127_5152791_34 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000002967 186.0
HKD2_k127_5152791_35 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000599 180.0
HKD2_k127_5152791_36 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000005242 179.0
HKD2_k127_5152791_37 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000004399 167.0
HKD2_k127_5152791_38 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000002049 163.0
HKD2_k127_5152791_39 PFAM MaoC like domain - - - 0.000000000000000000000000000000000000008639 158.0
HKD2_k127_5152791_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 9.84e-270 841.0
HKD2_k127_5152791_40 Histidine kinase - - - 0.00000000000000000000000000000000000002961 163.0
HKD2_k127_5152791_41 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000000000000000000000000000000000005639 146.0
HKD2_k127_5152791_42 HupE / UreJ protein - - - 0.000000000000000000000000000000000004105 154.0
HKD2_k127_5152791_43 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000005893 145.0
HKD2_k127_5152791_44 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000000000000001726 137.0
HKD2_k127_5152791_45 transporter antisigma-factor antagonist STAS K04749 - - 0.0000000000000000000000000002541 118.0
HKD2_k127_5152791_46 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000004161 126.0
HKD2_k127_5152791_47 Phospholipid methyltransferase - - - 0.000000000000000000000009416 108.0
HKD2_k127_5152791_49 SCO1/SenC K07152 - - 0.0000000000000001947 91.0
HKD2_k127_5152791_5 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 1.03e-256 808.0
HKD2_k127_5152791_50 - - - - 0.00000000000008267 75.0
HKD2_k127_5152791_51 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000001273 72.0
HKD2_k127_5152791_52 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000003136 63.0
HKD2_k127_5152791_53 TIGRFAM MoaD family protein K03636 - - 0.0000143 51.0
HKD2_k127_5152791_54 PFAM Uncharacterised protein family UPF0150 - - - 0.00007105 46.0
HKD2_k127_5152791_56 - - - - 0.000786 45.0
HKD2_k127_5152791_6 Protein of unknown function (DUF3604) - - - 2.501e-239 764.0
HKD2_k127_5152791_7 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 609.0
HKD2_k127_5152791_8 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 591.0
HKD2_k127_5152791_9 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 587.0
HKD2_k127_5157707_0 acyl-CoA dehydrogenase K00248,K00249 - 1.3.8.1,1.3.8.7 1.512e-230 718.0
HKD2_k127_5157707_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 592.0
HKD2_k127_5157707_11 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001028 249.0
HKD2_k127_5157707_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000000002372 182.0
HKD2_k127_5157707_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000009651 158.0
HKD2_k127_5157707_14 Putative DNA-binding domain - - - 0.0000000000000000000000000000000301 138.0
HKD2_k127_5157707_15 amino acid K03294,K13868 - - 0.000000000000000000000000000000353 129.0
HKD2_k127_5157707_16 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000008734 127.0
HKD2_k127_5157707_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000002939 122.0
HKD2_k127_5157707_18 DSBA-like thioredoxin domain - - - 0.000000000007255 73.0
HKD2_k127_5157707_19 - - - - 0.00000000001942 69.0
HKD2_k127_5157707_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 578.0
HKD2_k127_5157707_3 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 526.0
HKD2_k127_5157707_4 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 513.0
HKD2_k127_5157707_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 488.0
HKD2_k127_5157707_6 ATP synthesis coupled electron transport K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 398.0
HKD2_k127_5157707_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 384.0
HKD2_k127_5157707_8 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 373.0
HKD2_k127_5157707_9 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 351.0
HKD2_k127_5164220_0 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 462.0
HKD2_k127_5164220_1 TIGRFAM gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 462.0
HKD2_k127_5164220_10 glutathione transferase activity K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
HKD2_k127_5164220_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000044 249.0
HKD2_k127_5164220_12 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000005333 222.0
HKD2_k127_5164220_13 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000004467 217.0
HKD2_k127_5164220_14 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000001535 201.0
HKD2_k127_5164220_15 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000000000000000001127 179.0
HKD2_k127_5164220_16 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000003196 180.0
HKD2_k127_5164220_17 Stigma-specific protein, Stig1 - - - 0.000000000000000000000000000000001402 153.0
HKD2_k127_5164220_18 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000006388 132.0
HKD2_k127_5164220_19 lysyltransferase activity - - - 0.000000000000000000000000000456 126.0
HKD2_k127_5164220_2 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 398.0
HKD2_k127_5164220_20 Sterol carrier protein - - - 0.00000000000000000000000001443 112.0
HKD2_k127_5164220_21 Flavin and coenzyme A sequestration protein dodecin K09165 - - 0.0000000000000000000000001253 108.0
HKD2_k127_5164220_22 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000138 107.0
HKD2_k127_5164220_23 Hsp20/alpha crystallin family - - - 0.00000000000000000000002033 106.0
HKD2_k127_5164220_24 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000001068 89.0
HKD2_k127_5164220_25 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000602 85.0
HKD2_k127_5164220_26 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000002212 81.0
HKD2_k127_5164220_27 Protein of unknown function (DUF1232) - - - 0.000000000004491 70.0
HKD2_k127_5164220_28 Polymer-forming cytoskeletal - - - 0.00000000007056 69.0
HKD2_k127_5164220_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006608 404.0
HKD2_k127_5164220_30 AraC-like ligand binding domain - - - 0.0000000007259 71.0
HKD2_k127_5164220_31 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000004203 66.0
HKD2_k127_5164220_32 Outer membrane lipoprotein-sorting protein - - - 0.00003595 54.0
HKD2_k127_5164220_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 362.0
HKD2_k127_5164220_5 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 350.0
HKD2_k127_5164220_6 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 349.0
HKD2_k127_5164220_7 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 326.0
HKD2_k127_5164220_8 oxidoreductase activity, acting on CH-OH group of donors K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 300.0
HKD2_k127_5164220_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 - 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006861 272.0
HKD2_k127_5167337_0 PFAM NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 455.0
HKD2_k127_5167337_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 415.0
HKD2_k127_5167337_2 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 384.0
HKD2_k127_5167337_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 379.0
HKD2_k127_5167337_4 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 373.0
HKD2_k127_5167337_5 Elongator protein 3, MiaB family, Radical SAM K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.0008326 44.0
HKD2_k127_5229974_0 - - - - 2.681e-210 675.0
HKD2_k127_5229974_1 DEAD DEAH box helicase K03654 - 3.6.4.12 9.967e-197 631.0
HKD2_k127_5229974_10 Pfam:DUF385 - - - 0.000000000000000000000000000000000005773 145.0
HKD2_k127_5229974_11 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000004537 104.0
HKD2_k127_5229974_12 6-phosphogluconolactonase activity - - - 0.0000000006233 74.0
HKD2_k127_5229974_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 613.0
HKD2_k127_5229974_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 488.0
HKD2_k127_5229974_4 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 446.0
HKD2_k127_5229974_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 363.0
HKD2_k127_5229974_6 Pkd domain containing protein K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002786 275.0
HKD2_k127_5229974_7 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001312 253.0
HKD2_k127_5229974_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000001896 167.0
HKD2_k127_5229974_9 - - - - 0.000000000000000000000000000000000000007225 147.0
HKD2_k127_5258007_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 599.0
HKD2_k127_5258007_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 481.0
HKD2_k127_5268396_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006688 540.0
HKD2_k127_5268396_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 519.0
HKD2_k127_5268396_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 450.0
HKD2_k127_5268396_3 Probable molybdopterin binding domain K03742 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 342.0
HKD2_k127_5268396_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00172,K00441 - 1.12.98.1,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007239 257.0
HKD2_k127_5268396_5 enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000006735 237.0
HKD2_k127_5268396_6 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000002377 150.0
HKD2_k127_5299483_0 Cytochrome C and Quinol oxidase polypeptide I K00404 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 6.931e-206 644.0
HKD2_k127_5299483_1 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 371.0
HKD2_k127_5299483_2 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 317.0
HKD2_k127_5299483_3 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000008717 231.0
HKD2_k127_5299483_4 cytochrome oxidase K00407 - - 0.00000000000728 66.0
HKD2_k127_5344799_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1250.0
HKD2_k127_5344799_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 402.0
HKD2_k127_5344799_2 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 338.0
HKD2_k127_5344799_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007136 282.0
HKD2_k127_5344799_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000111 224.0
HKD2_k127_5344799_5 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000002488 132.0
HKD2_k127_5344799_6 Sugar (and other) transporter - - - 0.00000000000000000000008116 113.0
HKD2_k127_5344799_7 acetyltransferase - - - 0.0000000000000000000003622 107.0
HKD2_k127_5344799_9 negative regulation of translational initiation - - - 0.0005911 49.0
HKD2_k127_534760_0 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 604.0
HKD2_k127_534760_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 375.0
HKD2_k127_534760_2 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 339.0
HKD2_k127_534760_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000009202 237.0
HKD2_k127_534760_4 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000001597 182.0
HKD2_k127_534760_5 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000002147 131.0
HKD2_k127_534760_6 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000001492 104.0
HKD2_k127_534760_7 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.00000000000000000001759 103.0
HKD2_k127_534760_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000008337 75.0
HKD2_k127_5373943_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 461.0
HKD2_k127_5373943_1 ABC-type multidrug transport system ATPase and permease K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 376.0
HKD2_k127_5373943_10 subunit of a heme lyase K02200 - - 0.00000000000000007632 89.0
HKD2_k127_5373943_11 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000001549 72.0
HKD2_k127_5373943_13 - - - - 0.00009212 50.0
HKD2_k127_5373943_2 Glycosyl transferases group 1 K03842 - 2.4.1.142 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 340.0
HKD2_k127_5373943_3 GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity K03843,K20296 GO:0000009,GO:0000030,GO:0000033,GO:0003674,GO:0003824,GO:0004376,GO:0004378,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0005856,GO:0006464,GO:0006486,GO:0006487,GO:0006488,GO:0006490,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010035,GO:0010038,GO:0012505,GO:0015629,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0030176,GO:0031224,GO:0031227,GO:0031984,GO:0033164,GO:0033577,GO:0034645,GO:0036211,GO:0042175,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046982,GO:0046983,GO:0047485,GO:0048306,GO:0048471,GO:0050896,GO:0051592,GO:0070085,GO:0071704,GO:0097502,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.132,2.4.1.257 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 319.0
HKD2_k127_5373943_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000005085 237.0
HKD2_k127_5373943_5 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000001935 240.0
HKD2_k127_5373943_6 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000004212 227.0
HKD2_k127_5373943_7 PFAM NHL repeat containing protein K13735 - - 0.0000000000000000000000000000000000000000000000000000000001278 228.0
HKD2_k127_5373943_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000003871 220.0
HKD2_k127_5373943_9 Tetratricopeptide repeat protein - - - 0.000000000000000000000000000000002885 147.0
HKD2_k127_5397090_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 593.0
HKD2_k127_5397090_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 434.0
HKD2_k127_5397090_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 386.0
HKD2_k127_5397090_3 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 354.0
HKD2_k127_5397090_4 - - - - 0.000000000000005434 84.0
HKD2_k127_5397090_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00003199 57.0
HKD2_k127_5398600_0 belongs to the aldehyde dehydrogenase family K00130,K00151 - 1.2.1.60,1.2.1.8 2.023e-224 709.0
HKD2_k127_5398600_1 Biotin carboxylase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 591.0
HKD2_k127_5398600_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000002438 123.0
HKD2_k127_5398600_11 Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family K19429 - - 0.00000000000000000002415 100.0
HKD2_k127_5398600_12 O-acyltransferase activity - - - 0.000000000000000001456 91.0
HKD2_k127_5398600_13 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000003749 82.0
HKD2_k127_5398600_14 rRNA (guanine-N2-)-methyltransferase activity - - - 0.0000000007696 70.0
HKD2_k127_5398600_2 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K16901,K21184,K21726 - 1.14.13.166,1.14.13.29,1.14.14.15,1.14.14.8,1.14.14.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 554.0
HKD2_k127_5398600_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 510.0
HKD2_k127_5398600_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 390.0
HKD2_k127_5398600_5 Fumarylacetoacetate (FAA) hydrolase family K05921 - 4.1.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 311.0
HKD2_k127_5398600_6 3,4-dihydroxyphenylacetate 2,3-dioxygenase' K00455 - 1.13.11.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 305.0
HKD2_k127_5398600_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 301.0
HKD2_k127_5398600_8 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000000000000000000000000000005315 194.0
HKD2_k127_5398600_9 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000004571 191.0
HKD2_k127_5422669_0 Acetyl-CoA carboxylase, central region - - - 0.0 2062.0
HKD2_k127_5422669_1 Ketoacyl-synthetase C-terminal extension - - - 0.0 1139.0
HKD2_k127_5422669_10 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
HKD2_k127_5422669_11 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 320.0
HKD2_k127_5422669_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 304.0
HKD2_k127_5422669_13 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004797 280.0
HKD2_k127_5422669_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002621 266.0
HKD2_k127_5422669_15 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000009906 264.0
HKD2_k127_5422669_16 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000001824 259.0
HKD2_k127_5422669_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000498 257.0
HKD2_k127_5422669_18 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000001816 238.0
HKD2_k127_5422669_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
HKD2_k127_5422669_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.251e-215 677.0
HKD2_k127_5422669_20 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000002761 218.0
HKD2_k127_5422669_21 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000004109 212.0
HKD2_k127_5422669_22 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000005007 209.0
HKD2_k127_5422669_23 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000173 179.0
HKD2_k127_5422669_24 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000002 155.0
HKD2_k127_5422669_25 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000002031 142.0
HKD2_k127_5422669_26 SCO1/SenC K07152 - - 0.0000000000000000000000000000000001399 141.0
HKD2_k127_5422669_27 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000281 133.0
HKD2_k127_5422669_28 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000005823 136.0
HKD2_k127_5422669_29 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000005802 114.0
HKD2_k127_5422669_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 458.0
HKD2_k127_5422669_30 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000006585 96.0
HKD2_k127_5422669_32 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00004346 56.0
HKD2_k127_5422669_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 460.0
HKD2_k127_5422669_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 450.0
HKD2_k127_5422669_6 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 367.0
HKD2_k127_5422669_7 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 378.0
HKD2_k127_5422669_8 PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 341.0
HKD2_k127_5422669_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 332.0
HKD2_k127_543545_0 glutamate synthase K00284 - 1.4.7.1 1.433e-216 697.0
HKD2_k127_543545_1 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 495.0
HKD2_k127_543545_10 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000002553 137.0
HKD2_k127_543545_11 Urate oxidase N-terminal - - - 0.00000000000000000000000000000002912 137.0
HKD2_k127_543545_12 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000001002 128.0
HKD2_k127_543545_13 Glutathione S-transferase, C-terminal domain K03599 - - 0.000000000000000000000000000003117 130.0
HKD2_k127_543545_14 Belongs to the Fur family K09825 - - 0.00000000000000000000004909 104.0
HKD2_k127_543545_16 Cystathionine beta-lyase K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000002003 55.0
HKD2_k127_543545_17 MoaE protein - - - 0.000006327 51.0
HKD2_k127_543545_2 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 462.0
HKD2_k127_543545_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 349.0
HKD2_k127_543545_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 362.0
HKD2_k127_543545_5 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
HKD2_k127_543545_6 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003267 257.0
HKD2_k127_543545_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000003085 194.0
HKD2_k127_543545_8 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000001567 194.0
HKD2_k127_543545_9 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000000002033 192.0
HKD2_k127_5460550_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 589.0
HKD2_k127_5460550_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 412.0
HKD2_k127_5460550_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
HKD2_k127_5460550_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 303.0
HKD2_k127_5460550_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 313.0
HKD2_k127_5460550_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000003134 220.0
HKD2_k127_5460550_6 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000003027 170.0
HKD2_k127_5460550_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000004452 85.0
HKD2_k127_5460550_8 Glutathione S-transferase - - - 0.0000000000000001335 81.0
HKD2_k127_5517697_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1010.0
HKD2_k127_5517697_1 Belongs to the peptidase S16 family - - - 1.822e-194 639.0
HKD2_k127_5517697_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000002201 148.0
HKD2_k127_5517697_11 MOSC N-terminal beta barrel domain - - - 0.00000000000000000000004257 102.0
HKD2_k127_5517697_12 - - - - 0.0000000000003665 72.0
HKD2_k127_5517697_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0001601 54.0
HKD2_k127_5517697_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 520.0
HKD2_k127_5517697_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 483.0
HKD2_k127_5517697_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 469.0
HKD2_k127_5517697_5 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 437.0
HKD2_k127_5517697_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000002408 222.0
HKD2_k127_5517697_7 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000001676 207.0
HKD2_k127_5517697_8 MOSC domain containing protein K07140 - - 0.000000000000000000000000000000000000000000000004736 180.0
HKD2_k127_5517697_9 KR domain K08261,K21620 - 1.1.1.16,1.1.99.21 0.000000000000000000000000000000000000001395 159.0
HKD2_k127_5571894_0 ABC transporter K06020 - 3.6.3.25 2.74e-254 795.0
HKD2_k127_5571894_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 439.0
HKD2_k127_5571894_10 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein K03790 - 2.3.1.128 0.00000000000000000000000000000000000002188 152.0
HKD2_k127_5571894_11 Alpha beta hydrolase - - - 0.00000000000000000000000000000004647 142.0
HKD2_k127_5571894_12 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000007207 126.0
HKD2_k127_5571894_13 PHP-associated - - - 0.000000000000000000000000000206 124.0
HKD2_k127_5571894_14 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000004475 100.0
HKD2_k127_5571894_15 Ribosomal protein S16 K02959 - - 0.0000000000000000000005942 98.0
HKD2_k127_5571894_16 dehydratase - - - 0.000000142 59.0
HKD2_k127_5571894_17 dehydratase - - - 0.000002317 55.0
HKD2_k127_5571894_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 398.0
HKD2_k127_5571894_3 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 387.0
HKD2_k127_5571894_4 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 293.0
HKD2_k127_5571894_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002729 271.0
HKD2_k127_5571894_6 SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000000000000000000000000001019 201.0
HKD2_k127_5571894_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000001088 200.0
HKD2_k127_5571894_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000002121 179.0
HKD2_k127_5571894_9 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000001514 153.0
HKD2_k127_5576444_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 576.0
HKD2_k127_5576444_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001389 280.0
HKD2_k127_5576444_2 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007893 235.0
HKD2_k127_5576444_3 PFAM Silent information regulator protein Sir2 K12410 - - 0.00000000000000000000000000000000000000000000000000000000002756 218.0
HKD2_k127_5576444_4 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.000000000000000000000000000000000000003602 156.0
HKD2_k127_5580242_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.826e-248 775.0
HKD2_k127_5580242_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.533e-220 695.0
HKD2_k127_5580242_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000159 207.0
HKD2_k127_5580242_11 - K03561,K12287 - - 0.00000000000000000000000000000000000000000000000000006995 216.0
HKD2_k127_5580242_12 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000001197 192.0
HKD2_k127_5580242_13 MaoC like domain - - - 0.00000000000000000000000000000001529 139.0
HKD2_k127_5580242_14 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000002377 116.0
HKD2_k127_5580242_15 Clostripain family - - - 0.00000000000000000000003945 118.0
HKD2_k127_5580242_17 guanyl-nucleotide exchange factor activity K05349,K13735,K18491,K20276 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.2.1.21 0.000000000003764 81.0
HKD2_k127_5580242_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 369.0
HKD2_k127_5580242_3 SIS domain K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 365.0
HKD2_k127_5580242_4 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 368.0
HKD2_k127_5580242_5 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 353.0
HKD2_k127_5580242_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009055,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0022900,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001797 267.0
HKD2_k127_5580242_7 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000002292 276.0
HKD2_k127_5580242_8 COGs COG2912 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000006793 235.0
HKD2_k127_5580242_9 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000008129 225.0
HKD2_k127_5644706_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 626.0
HKD2_k127_5644706_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 597.0
HKD2_k127_5644706_10 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.000000000000000000000000000000000000004647 158.0
HKD2_k127_5644706_11 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000007 142.0
HKD2_k127_5644706_12 Survival protein SurE - - - 0.000000000000000000000000000000001908 142.0
HKD2_k127_5644706_13 VanZ like family - - - 0.0000000000000000000000000001099 122.0
HKD2_k127_5644706_14 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000001985 110.0
HKD2_k127_5644706_15 e3 binding domain - - - 0.000000000000000002806 87.0
HKD2_k127_5644706_16 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000007347 86.0
HKD2_k127_5644706_17 HWE histidine kinase - - - 0.00000000007476 74.0
HKD2_k127_5644706_19 Rieske [2Fe-2S] domain - - - 0.0004761 48.0
HKD2_k127_5644706_2 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 529.0
HKD2_k127_5644706_3 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 382.0
HKD2_k127_5644706_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 293.0
HKD2_k127_5644706_5 transporter (mgtE) K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001438 289.0
HKD2_k127_5644706_6 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001337 278.0
HKD2_k127_5644706_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000003291 229.0
HKD2_k127_5644706_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000002293 217.0
HKD2_k127_5644706_9 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000000000001267 208.0
HKD2_k127_5755156_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 291.0
HKD2_k127_5755156_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000789 261.0
HKD2_k127_5755156_2 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000001436 214.0
HKD2_k127_5755156_3 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000003225 211.0
HKD2_k127_5755156_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000007813 196.0
HKD2_k127_5755156_5 Domain of unknown function (DUF4956) - - - 0.000000000000000000000000000000000000000000001014 173.0
HKD2_k127_5755156_6 alpha-ribazole phosphatase activity - - - 0.000000000000000000000004217 115.0
HKD2_k127_5755156_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000003364 93.0
HKD2_k127_5755156_8 efflux transmembrane transporter activity - - - 0.00000002207 66.0
HKD2_k127_5755156_9 VTC domain - - - 0.0000001193 63.0
HKD2_k127_5891153_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 8.416e-244 784.0
HKD2_k127_5891153_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 583.0
HKD2_k127_5891153_10 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000003815 213.0
HKD2_k127_5891153_11 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000000000001448 188.0
HKD2_k127_5891153_12 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03087 - - 0.00000000000000000000000000000000000000000000007124 185.0
HKD2_k127_5891153_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000004474 136.0
HKD2_k127_5891153_14 Transketolase, pyrimidine binding domain - - - 0.000000000000000000000000000003082 121.0
HKD2_k127_5891153_15 Phosphopantetheine attachment site - - - 0.000000000000000009012 90.0
HKD2_k127_5891153_16 Belongs to the 'phage' integrase family - - - 0.00000001579 65.0
HKD2_k127_5891153_2 Major facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 444.0
HKD2_k127_5891153_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 411.0
HKD2_k127_5891153_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 402.0
HKD2_k127_5891153_5 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 394.0
HKD2_k127_5891153_6 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 381.0
HKD2_k127_5891153_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001562 276.0
HKD2_k127_5891153_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000006864 239.0
HKD2_k127_5891153_9 PFAM Cold-shock protein, DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000000000007243 234.0
HKD2_k127_6396976_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.284e-223 704.0
HKD2_k127_6396976_1 AMP-binding enzyme K02182 - 6.2.1.48 1.822e-201 640.0
HKD2_k127_6396976_10 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000002551 106.0
HKD2_k127_6396976_12 Zn-dependent protease with chaperone function - - - 0.0003168 53.0
HKD2_k127_6396976_2 Molydopterin dinucleotide binding domain K17050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 465.0
HKD2_k127_6396976_3 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 441.0
HKD2_k127_6396976_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 373.0
HKD2_k127_6396976_5 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HKD2_k127_6396976_6 Wax ester synthase-like Acyl-CoA acyltransferase domain - GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009268,GO:0009628,GO:0009987,GO:0010035,GO:0010447,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 319.0
HKD2_k127_6396976_7 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 301.0
HKD2_k127_6396976_8 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000112 237.0
HKD2_k127_6396976_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000009625 207.0
HKD2_k127_6409053_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1197.0
HKD2_k127_6409053_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 5.805e-223 708.0
HKD2_k127_6409053_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 460.0
HKD2_k127_6409053_11 Histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 418.0
HKD2_k127_6409053_12 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 403.0
HKD2_k127_6409053_13 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 388.0
HKD2_k127_6409053_14 calcium, potassium:sodium antiporter activity K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 362.0
HKD2_k127_6409053_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 330.0
HKD2_k127_6409053_16 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001191 274.0
HKD2_k127_6409053_17 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 267.0
HKD2_k127_6409053_18 TIGRFAM RHS repeat-associated core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004778 303.0
HKD2_k127_6409053_19 ATPase activity K02013,K09817 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000009062 269.0
HKD2_k127_6409053_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.573e-219 687.0
HKD2_k127_6409053_20 galactokinase activity K00849,K17781,K18674 GO:0000409,GO:0000411,GO:0000429,GO:0000431,GO:0000435,GO:0000436,GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005975,GO:0005996,GO:0006012,GO:0006355,GO:0006357,GO:0006793,GO:0006796,GO:0007154,GO:0007584,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019219,GO:0019222,GO:0019318,GO:0019320,GO:0019388,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031982,GO:0033036,GO:0033499,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043230,GO:0043231,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044421,GO:0044424,GO:0044464,GO:0045185,GO:0045893,GO:0045935,GO:0045944,GO:0045990,GO:0045991,GO:0046365,GO:0046835,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051235,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070062,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:1901575,GO:1902680,GO:1903506,GO:1903508,GO:1903561,GO:2000112,GO:2001141 2.7.1.157,2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001166 269.0
HKD2_k127_6409053_21 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006922 266.0
HKD2_k127_6409053_22 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000001217 256.0
HKD2_k127_6409053_23 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003154 253.0
HKD2_k127_6409053_24 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002649 240.0
HKD2_k127_6409053_25 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001034 240.0
HKD2_k127_6409053_26 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000002059 216.0
HKD2_k127_6409053_27 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000001392 206.0
HKD2_k127_6409053_28 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,5.4.2.8 0.000000000000000000000000000000000000000000000000000001579 204.0
HKD2_k127_6409053_29 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001362 194.0
HKD2_k127_6409053_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.317e-203 649.0
HKD2_k127_6409053_30 Lysin motif - - - 0.0000000000000000000000000000000000000000000002476 177.0
HKD2_k127_6409053_31 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000005506 171.0
HKD2_k127_6409053_32 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000006424 168.0
HKD2_k127_6409053_33 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000001579 150.0
HKD2_k127_6409053_34 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000001123 147.0
HKD2_k127_6409053_35 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000001763 131.0
HKD2_k127_6409053_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000303 133.0
HKD2_k127_6409053_37 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000232 122.0
HKD2_k127_6409053_38 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000109 120.0
HKD2_k127_6409053_39 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000006946 110.0
HKD2_k127_6409053_4 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 620.0
HKD2_k127_6409053_40 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.000000000000000000000003559 118.0
HKD2_k127_6409053_41 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000007615 108.0
HKD2_k127_6409053_42 IMP dehydrogenase activity - - - 0.0000000000000000000401 99.0
HKD2_k127_6409053_43 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000003866 85.0
HKD2_k127_6409053_44 Protein of unknown function (DUF721) - - - 0.000000000000000005673 93.0
HKD2_k127_6409053_45 - - - - 0.00000000000002569 77.0
HKD2_k127_6409053_46 Beta-lactamase superfamily domain - - - 0.000000000005006 71.0
HKD2_k127_6409053_47 Bacterial regulatory proteins, tetR family - - - 0.0000000001183 71.0
HKD2_k127_6409053_48 Dodecin K09165 - - 0.000008518 51.0
HKD2_k127_6409053_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 589.0
HKD2_k127_6409053_6 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 554.0
HKD2_k127_6409053_7 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 541.0
HKD2_k127_6409053_8 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 533.0
HKD2_k127_6409053_9 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 458.0
HKD2_k127_6419120_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.645e-321 999.0
HKD2_k127_6419120_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.109e-267 839.0
HKD2_k127_6419120_10 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001542 299.0
HKD2_k127_6419120_11 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000002462 214.0
HKD2_k127_6419120_12 Cytidylyltransferase-like K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000009687 205.0
HKD2_k127_6419120_13 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000008356 133.0
HKD2_k127_6419120_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K00969,K09710 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 2.7.7.18 0.000000000000000000000000000000004944 136.0
HKD2_k127_6419120_15 membrane transporter protein K07090 - - 0.0000000000000000000000000006365 123.0
HKD2_k127_6419120_16 Tetratricopeptide repeat - - - 0.000000000000000000000005264 116.0
HKD2_k127_6419120_17 - - - - 0.000000000000002108 79.0
HKD2_k127_6419120_18 Bacterial regulatory proteins, tetR family - - - 0.000000000000003653 84.0
HKD2_k127_6419120_19 Late embryogenesis abundant protein - - - 0.0000003555 62.0
HKD2_k127_6419120_2 oligoendopeptidase F K08602 - - 1.164e-203 653.0
HKD2_k127_6419120_20 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.000002938 58.0
HKD2_k127_6419120_3 synthetase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 612.0
HKD2_k127_6419120_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 507.0
HKD2_k127_6419120_5 Belongs to the ClpA ClpB family K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 470.0
HKD2_k127_6419120_6 Retinal pigment epithelial membrane protein K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 447.0
HKD2_k127_6419120_7 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 428.0
HKD2_k127_6419120_8 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 368.0
HKD2_k127_6419120_9 Glutathione S-transferase K00799,K03599 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 304.0
HKD2_k127_6470953_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 3.011e-244 775.0
HKD2_k127_6470953_1 ATPase associated with various cellular activities, AAA_5 K02584 - - 0.0000000001414 68.0
HKD2_k127_6470953_2 Protease prsW family - - - 0.00000002668 66.0
HKD2_k127_6470953_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000001563 53.0
HKD2_k127_648799_0 Glycolate oxidase subunit K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 569.0
HKD2_k127_648799_1 aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 505.0
HKD2_k127_648799_10 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000003904 92.0
HKD2_k127_648799_11 - - - - 0.00000000000005592 73.0
HKD2_k127_648799_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 484.0
HKD2_k127_648799_3 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 299.0
HKD2_k127_648799_4 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000005658 251.0
HKD2_k127_648799_5 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000007094 231.0
HKD2_k127_648799_6 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000008183 235.0
HKD2_k127_648799_7 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000552 187.0
HKD2_k127_648799_8 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000002582 147.0
HKD2_k127_6488565_0 PQQ enzyme repeat K00117 - 1.1.5.2 1.005e-211 679.0
HKD2_k127_6488565_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 519.0
HKD2_k127_6488565_10 lactoylglutathione lyase activity - - - 0.00000000000000000000003241 102.0
HKD2_k127_6488565_11 AIG2-like family - - - 0.0000000000000000000004411 102.0
HKD2_k127_6488565_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000001363 98.0
HKD2_k127_6488565_13 acyl-CoA hydrolase activity - - - 0.0000000000000008686 80.0
HKD2_k127_6488565_2 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 460.0
HKD2_k127_6488565_3 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 439.0
HKD2_k127_6488565_4 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 372.0
HKD2_k127_6488565_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 360.0
HKD2_k127_6488565_6 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 341.0
HKD2_k127_6488565_7 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000003758 237.0
HKD2_k127_6488565_8 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000000000000000000000009684 199.0
HKD2_k127_6488565_9 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000002837 125.0
HKD2_k127_6523227_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 442.0
HKD2_k127_6523227_1 Mur ligase, middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 424.0
HKD2_k127_6523227_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000001411 213.0
HKD2_k127_6523227_11 Transglycosylase SLT domain K06381,K08309 - - 0.00000000000000000000000000000000000000000000000002794 202.0
HKD2_k127_6523227_12 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000006035 179.0
HKD2_k127_6523227_13 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000436 171.0
HKD2_k127_6523227_14 - - - - 0.0000000000000000000000000000000000000004739 169.0
HKD2_k127_6523227_15 MarR family - - - 0.000000000000000000000000000003587 125.0
HKD2_k127_6523227_16 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000002633 130.0
HKD2_k127_6523227_17 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000005064 111.0
HKD2_k127_6523227_18 Cytochrome c K08738 - - 0.0000000000000000000006199 99.0
HKD2_k127_6523227_19 Metallo-beta-lactamase superfamily - - - 0.00000000000000003765 94.0
HKD2_k127_6523227_2 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 394.0
HKD2_k127_6523227_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
HKD2_k127_6523227_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005682 288.0
HKD2_k127_6523227_5 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003517 253.0
HKD2_k127_6523227_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000002868 236.0
HKD2_k127_6523227_7 Inositol monophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000001273 233.0
HKD2_k127_6523227_8 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000003307 230.0
HKD2_k127_6523227_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001883 221.0
HKD2_k127_6567123_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1227.0
HKD2_k127_6567123_1 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1053.0
HKD2_k127_6567123_10 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 437.0
HKD2_k127_6567123_11 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 435.0
HKD2_k127_6567123_12 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 381.0
HKD2_k127_6567123_13 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 363.0
HKD2_k127_6567123_14 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 354.0
HKD2_k127_6567123_15 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 351.0
HKD2_k127_6567123_16 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 359.0
HKD2_k127_6567123_17 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K00344 - 1.1.1.1,1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 342.0
HKD2_k127_6567123_18 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 334.0
HKD2_k127_6567123_19 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 332.0
HKD2_k127_6567123_2 Dehydrogenase E1 component K00164 - 1.2.4.2 2.106e-292 923.0
HKD2_k127_6567123_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 304.0
HKD2_k127_6567123_21 transcription factor binding K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 309.0
HKD2_k127_6567123_22 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 287.0
HKD2_k127_6567123_23 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001227 274.0
HKD2_k127_6567123_24 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001256 269.0
HKD2_k127_6567123_25 PFAM glycosyl transferase family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008144 273.0
HKD2_k127_6567123_26 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000002602 268.0
HKD2_k127_6567123_27 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000553 275.0
HKD2_k127_6567123_28 META domain - - - 0.0000000000000000000000000000000000000000000000000000000005995 211.0
HKD2_k127_6567123_29 Tetraacyldisaccharide-1-P 4'-kinase K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000008867 201.0
HKD2_k127_6567123_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 617.0
HKD2_k127_6567123_30 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000001764 190.0
HKD2_k127_6567123_31 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000143 181.0
HKD2_k127_6567123_32 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000006529 169.0
HKD2_k127_6567123_33 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000009673 167.0
HKD2_k127_6567123_34 PFAM glycosyl transferase, family 9 K02841 - - 0.00000000000000000000000000000000000001046 166.0
HKD2_k127_6567123_35 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000002794 147.0
HKD2_k127_6567123_36 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000001709 138.0
HKD2_k127_6567123_37 - - - - 0.0000000000000000000000000000002826 138.0
HKD2_k127_6567123_38 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000000000000003058 129.0
HKD2_k127_6567123_39 Belongs to the UPF0434 family K09791 - - 0.000000000000000000006243 95.0
HKD2_k127_6567123_4 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 610.0
HKD2_k127_6567123_40 - K01822 - 5.3.3.1 0.000000000000000000071 94.0
HKD2_k127_6567123_42 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0050896,GO:0051704,GO:0051716,GO:0071496 - 0.000000000000005216 85.0
HKD2_k127_6567123_43 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000002151 86.0
HKD2_k127_6567123_44 Putative regulatory protein - - - 0.0000001494 56.0
HKD2_k127_6567123_45 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.0000003042 58.0
HKD2_k127_6567123_46 PD-(D/E)XK nuclease superfamily - - - 0.000002095 50.0
HKD2_k127_6567123_5 ABC transporter K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 585.0
HKD2_k127_6567123_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 520.0
HKD2_k127_6567123_7 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 520.0
HKD2_k127_6567123_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 499.0
HKD2_k127_6567123_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 514.0
HKD2_k127_6671618_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 5.389e-216 676.0
HKD2_k127_6671618_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.456e-215 676.0
HKD2_k127_6671618_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006752 287.0
HKD2_k127_6671618_3 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000002437 216.0
HKD2_k127_6671618_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000004981 175.0
HKD2_k127_6671618_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000001759 171.0
HKD2_k127_6671618_6 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001864 150.0
HKD2_k127_6671618_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000005088 112.0
HKD2_k127_667778_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 416.0
HKD2_k127_667778_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 356.0
HKD2_k127_667778_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000007519 156.0
HKD2_k127_667778_11 GtrA-like protein K00995 - 2.7.8.5 0.0000000000000000000000000000000003721 141.0
HKD2_k127_667778_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.000000000000000000000000000001245 126.0
HKD2_k127_667778_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000002109 128.0
HKD2_k127_667778_14 Protein of unknown function (DUF971) K03593 - - 0.0000000000000000000000002686 109.0
HKD2_k127_667778_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 358.0
HKD2_k127_667778_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 331.0
HKD2_k127_667778_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 332.0
HKD2_k127_667778_5 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 318.0
HKD2_k127_667778_6 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000003553 269.0
HKD2_k127_667778_7 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000006043 204.0
HKD2_k127_667778_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000003098 208.0
HKD2_k127_667778_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000007007 169.0
HKD2_k127_6793704_0 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000951 173.0
HKD2_k127_6793704_1 AAA ATPase domain - - - 0.00000000000000000000000000000000000000001404 164.0
HKD2_k127_6793704_2 Histidine kinase - - - 0.00001533 58.0
HKD2_k127_6815503_0 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 391.0
HKD2_k127_6815503_1 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002593 297.0
HKD2_k127_6815503_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000002587 184.0
HKD2_k127_6815503_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000006061 158.0
HKD2_k127_6815503_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000008043 143.0
HKD2_k127_6815503_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000006501 137.0
HKD2_k127_6815503_6 NUDIX domain - - - 0.000000000000000000000000000001175 132.0
HKD2_k127_6815503_7 Transglutaminase-like K07184 - - 0.00000000000000000000000001069 118.0
HKD2_k127_6848383_0 Sulfatase K01130 - 3.1.6.1 8.363e-309 951.0
HKD2_k127_6848383_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000005347 220.0
HKD2_k127_6848383_10 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000124 98.0
HKD2_k127_6848383_11 Phage plasmid primase P4 family - - - 0.00000000000000004548 84.0
HKD2_k127_6848383_12 - - - - 0.0000000000000008461 85.0
HKD2_k127_6848383_13 PFAM Glycosyl transferase family 2 - - - 0.0000000000002429 82.0
HKD2_k127_6848383_14 Transposase - - - 0.0000004386 55.0
HKD2_k127_6848383_15 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0005006 52.0
HKD2_k127_6848383_2 - - - - 0.0000000000000000000000000000000000000000000000000000004384 201.0
HKD2_k127_6848383_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000001608 213.0
HKD2_k127_6848383_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000001055 193.0
HKD2_k127_6848383_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000005931 186.0
HKD2_k127_6848383_6 - - - - 0.000000000000000000000000000000000000002079 164.0
HKD2_k127_6848383_7 - - - - 0.00000000000000000000000000000000001046 139.0
HKD2_k127_6848383_8 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000004227 112.0
HKD2_k127_6848383_9 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000001959 91.0
HKD2_k127_6896720_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 607.0
HKD2_k127_6896720_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 499.0
HKD2_k127_6896720_10 CAAX amino terminal protease family protein K07052 - - 0.00000000000000000000000009302 114.0
HKD2_k127_6896720_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 503.0
HKD2_k127_6896720_3 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 452.0
HKD2_k127_6896720_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 408.0
HKD2_k127_6896720_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 382.0
HKD2_k127_6896720_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000008372 173.0
HKD2_k127_6896720_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001096 137.0
HKD2_k127_6896720_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000002828 137.0
HKD2_k127_6896720_9 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000002582 125.0
HKD2_k127_6909594_0 SecA preprotein cross-linking domain K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 387.0
HKD2_k127_6909594_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 334.0
HKD2_k127_6909594_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001814 271.0
HKD2_k127_6909594_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000008436 184.0
HKD2_k127_6909594_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000001686 149.0
HKD2_k127_6909594_5 Thioredoxin - - - 0.00000000000000000000000000000001277 131.0
HKD2_k127_6909594_6 Protein-disulfide isomerase - - - 0.00003864 50.0
HKD2_k127_6925893_0 NADH Ubiquinone plastoquinone (complex I) K05565 - - 1.08e-220 707.0
HKD2_k127_6925893_1 Peptidase family M41 K03798 - - 6.268e-211 674.0
HKD2_k127_6925893_10 histidine kinase A domain protein - - - 0.0000000000000000000002714 110.0
HKD2_k127_6925893_11 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000000000000000003465 102.0
HKD2_k127_6925893_12 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000001248 102.0
HKD2_k127_6925893_13 - - - - 0.00000001224 61.0
HKD2_k127_6925893_14 Transposase and inactivated derivatives K07497 - - 0.00003292 49.0
HKD2_k127_6925893_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 550.0
HKD2_k127_6925893_3 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 411.0
HKD2_k127_6925893_4 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 405.0
HKD2_k127_6925893_5 GAF domain - - - 0.0000000000000000000000000000000000000000000000001812 192.0
HKD2_k127_6925893_6 PFAM Na H antiporter MnhB subunit-related protein K05566 - - 0.00000000000000000000000000000000000000000001404 181.0
HKD2_k127_6925893_7 PFAM cation antiporter K05569 - - 0.00000000000000000000000000000000000000000009167 165.0
HKD2_k127_6925893_8 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000000000000000000000000001545 139.0
HKD2_k127_6925893_9 PFAM NADH-ubiquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000001016 135.0
HKD2_k127_6951860_0 transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 379.0
HKD2_k127_6951860_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 348.0
HKD2_k127_6951860_2 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 333.0
HKD2_k127_6951860_3 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000007254 233.0
HKD2_k127_6951860_4 efflux transmembrane transporter activity K12340 - - 0.0000000000000000000000000000000000000000000000000002686 203.0
HKD2_k127_70098_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.574e-274 852.0
HKD2_k127_70098_1 short chain dehydrogenase reductase family K18009 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
HKD2_k127_70098_2 transport system involved in gliding motility, auxiliary K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003957 271.0
HKD2_k127_70098_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000007854 193.0
HKD2_k127_70098_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000001126 147.0
HKD2_k127_70098_5 GatB YqeY K09117 - - 0.00000000004635 69.0
HKD2_k127_70098_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00085 45.0
HKD2_k127_7053039_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.288e-235 743.0
HKD2_k127_7053039_1 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 503.0
HKD2_k127_7053039_10 - - - - 0.0000007793 59.0
HKD2_k127_7053039_2 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 350.0
HKD2_k127_7053039_3 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 332.0
HKD2_k127_7053039_4 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000147 273.0
HKD2_k127_7053039_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000002358 178.0
HKD2_k127_7053039_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000002078 169.0
HKD2_k127_7053039_7 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000005352 151.0
HKD2_k127_7053039_8 Regulatory protein, FmdB family - - - 0.0000000000000000000000000001193 123.0
HKD2_k127_7053039_9 Universal stress protein family - - - 0.000000000000005775 81.0
HKD2_k127_7120044_0 PAS domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 576.0
HKD2_k127_7120044_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 482.0
HKD2_k127_7120044_10 Tyrosine phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000001995 173.0
HKD2_k127_7120044_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000548 136.0
HKD2_k127_7120044_12 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000209 100.0
HKD2_k127_7120044_13 DNA primase activity - - - 0.000000000000008766 87.0
HKD2_k127_7120044_14 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000005545 54.0
HKD2_k127_7120044_2 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 411.0
HKD2_k127_7120044_3 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 403.0
HKD2_k127_7120044_4 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 375.0
HKD2_k127_7120044_5 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 371.0
HKD2_k127_7120044_6 acyl-CoA hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006651 268.0
HKD2_k127_7120044_7 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000003347 245.0
HKD2_k127_7120044_8 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004124 258.0
HKD2_k127_7120044_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000003048 205.0
HKD2_k127_7425838_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 413.0
HKD2_k127_7425838_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 335.0
HKD2_k127_7425838_2 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000309 280.0
HKD2_k127_7425838_3 FabA-like domain K02372 - 4.2.1.59 0.00000000000000000000000000000832 129.0
HKD2_k127_745233_0 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001217 304.0
HKD2_k127_745233_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001034 254.0
HKD2_k127_745233_10 Protein of unknown function (DUF2878) - - - 0.0000000000000000000000000001001 126.0
HKD2_k127_745233_11 ABC-type cobalt transport system, permease component - - - 0.0000000000000000000001722 109.0
HKD2_k127_745233_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000001483 88.0
HKD2_k127_745233_13 Virulence activator alpha C-term - - - 0.000000000001915 79.0
HKD2_k127_745233_14 CDP-alcohol phosphatidyltransferase K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000006067 67.0
HKD2_k127_745233_15 Lamin Tail Domain - - - 0.00000004813 66.0
HKD2_k127_745233_16 cobalt transport protein K16785 - - 0.000001546 59.0
HKD2_k127_745233_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000001662 59.0
HKD2_k127_745233_2 PFAM ABC transporter related K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008502 259.0
HKD2_k127_745233_3 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000001075 242.0
HKD2_k127_745233_4 TonB dependent receptor K02014,K16089 - - 0.0000000000000000000000000000000000000000000000000000000000001386 239.0
HKD2_k127_745233_5 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000001408 219.0
HKD2_k127_745233_6 tRNA wobble cytosine modification - - - 0.000000000000000000000000000000000000000000000000653 184.0
HKD2_k127_745233_7 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000003792 179.0
HKD2_k127_745233_8 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.00000000000000000000000000000000000000000001163 166.0
HKD2_k127_745233_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000005023 158.0
HKD2_k127_7474819_0 COG0464 ATPases of the AAA class - - - 1.509e-231 725.0
HKD2_k127_7474819_1 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 484.0
HKD2_k127_7474819_10 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000007047 249.0
HKD2_k127_7474819_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000004476 213.0
HKD2_k127_7474819_12 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000004235 178.0
HKD2_k127_7474819_14 Transcriptional regulator - - - 0.000000000000000000000000006053 113.0
HKD2_k127_7474819_15 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000001312 117.0
HKD2_k127_7474819_16 GAF domain - - - 0.00000000000000000000001765 116.0
HKD2_k127_7474819_17 Biopolymer transport protein K03559 - - 0.000000000000000003588 93.0
HKD2_k127_7474819_18 Tetratricopeptide repeat - - - 0.00009159 48.0
HKD2_k127_7474819_2 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 473.0
HKD2_k127_7474819_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 448.0
HKD2_k127_7474819_4 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 424.0
HKD2_k127_7474819_5 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 398.0
HKD2_k127_7474819_6 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 387.0
HKD2_k127_7474819_7 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 372.0
HKD2_k127_7474819_8 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003508 285.0
HKD2_k127_7474819_9 F420-0:Gamma-glutamyl ligase K12234 GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000001693 242.0
HKD2_k127_7674966_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1257.0
HKD2_k127_7674966_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.582e-268 861.0
HKD2_k127_7674966_10 PFAM CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 367.0
HKD2_k127_7674966_11 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 353.0
HKD2_k127_7674966_12 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 343.0
HKD2_k127_7674966_13 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 319.0
HKD2_k127_7674966_14 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 295.0
HKD2_k127_7674966_15 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005255 285.0
HKD2_k127_7674966_16 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001294 276.0
HKD2_k127_7674966_17 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000008413 254.0
HKD2_k127_7674966_18 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000001656 211.0
HKD2_k127_7674966_19 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000009606 200.0
HKD2_k127_7674966_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.026e-216 685.0
HKD2_k127_7674966_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000009686 171.0
HKD2_k127_7674966_21 Protein of unknown function (DUF1329) - - - 0.00000000000000000000000000000000001222 151.0
HKD2_k127_7674966_22 YbbR-like protein - - - 0.0000000000000000000000000000000005142 145.0
HKD2_k127_7674966_23 ATP GTP hydrolase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000002947 138.0
HKD2_k127_7674966_24 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000006633 116.0
HKD2_k127_7674966_25 Pro-kumamolisin, activation domain K08677 - - 0.000000000001557 74.0
HKD2_k127_7674966_3 Flavin containing amine oxidoreductase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 4.166e-211 665.0
HKD2_k127_7674966_4 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 519.0
HKD2_k127_7674966_5 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 515.0
HKD2_k127_7674966_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 490.0
HKD2_k127_7674966_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 446.0
HKD2_k127_7674966_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 426.0
HKD2_k127_7674966_9 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 379.0
HKD2_k127_7676902_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.616e-247 778.0
HKD2_k127_7676902_1 peptidase S9 prolyl oligopeptidase active site domain protein - - - 2.24e-237 755.0
HKD2_k127_7676902_10 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000177 251.0
HKD2_k127_7676902_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005646 228.0
HKD2_k127_7676902_12 PFAM Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000001212 212.0
HKD2_k127_7676902_13 PFAM N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000004081 172.0
HKD2_k127_7676902_14 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000746 142.0
HKD2_k127_7676902_15 PFAM biotin lipoyl attachment domain-containing protein - - - 0.000000000000007848 87.0
HKD2_k127_7676902_16 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00008835 48.0
HKD2_k127_7676902_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 585.0
HKD2_k127_7676902_3 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 519.0
HKD2_k127_7676902_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 436.0
HKD2_k127_7676902_5 homoserine kinase type II (Protein kinase fold) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 344.0
HKD2_k127_7676902_6 Electron transfer flavoprotein, beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 306.0
HKD2_k127_7676902_7 electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 299.0
HKD2_k127_7676902_8 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000187 282.0
HKD2_k127_7676902_9 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006515 287.0
HKD2_k127_7681393_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 6.612e-241 784.0
HKD2_k127_7681393_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 1.431e-218 723.0
HKD2_k127_7681393_10 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000004853 51.0
HKD2_k127_7681393_2 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 599.0
HKD2_k127_7681393_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 476.0
HKD2_k127_7681393_4 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000004584 202.0
HKD2_k127_7681393_5 YGGT family K02221 - - 0.0000000000000000000000000000000001633 134.0
HKD2_k127_7681393_6 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000001504 135.0
HKD2_k127_7681393_7 lysyltransferase activity K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 0.0000000000000000000000000001121 130.0
HKD2_k127_7681393_8 Putative regulatory protein - - - 0.00000000000000000002575 94.0
HKD2_k127_7681393_9 Belongs to the UPF0235 family K09131 - - 0.00000000002507 72.0
HKD2_k127_7681968_0 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 563.0
HKD2_k127_7681968_1 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 543.0
HKD2_k127_7681968_10 Membrane - - - 0.0000000000000002396 85.0
HKD2_k127_7681968_11 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0001472 51.0
HKD2_k127_7681968_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002077 278.0
HKD2_k127_7681968_3 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002632 285.0
HKD2_k127_7681968_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000138 201.0
HKD2_k127_7681968_5 Serine hydrolase K07002 - - 0.000000000000000000000000000000009527 141.0
HKD2_k127_7681968_6 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000001211 122.0
HKD2_k127_7681968_7 - - - - 0.0000000000000000000000000002049 116.0
HKD2_k127_7681968_8 - - - - 0.0000000000000000000000000005539 114.0
HKD2_k127_7681968_9 PFAM GGDEF domain containing protein - - - 0.0000000000000000004134 90.0
HKD2_k127_7703612_0 acetyl-CoA hydrolase transferase - - - 1.036e-198 641.0
HKD2_k127_7703612_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 537.0
HKD2_k127_7703612_10 - - - - 0.0002373 50.0
HKD2_k127_7703612_2 ABC transporter substrate-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 424.0
HKD2_k127_7703612_3 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
HKD2_k127_7703612_4 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 347.0
HKD2_k127_7703612_5 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000001086 195.0
HKD2_k127_7703612_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000119 181.0
HKD2_k127_7703612_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000002548 128.0
HKD2_k127_7703612_8 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000001156 104.0
HKD2_k127_7703612_9 - - - - 0.00000000000000000002545 95.0
HKD2_k127_7707531_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 370.0
HKD2_k127_7707531_1 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 338.0
HKD2_k127_7707531_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 324.0
HKD2_k127_7707531_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000001109 220.0
HKD2_k127_7707531_4 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000001051 147.0
HKD2_k127_7707531_5 Fibronectin fibrinogen-binding protein - - - 0.000000000000000000000000000002397 124.0
HKD2_k127_7707531_6 Cytochrome C' - - - 0.000000000000008309 80.0
HKD2_k127_7707531_7 Pyridoxamine 5'-phosphate oxidase - - - 0.000000006295 66.0
HKD2_k127_7707531_8 Acyl-ACP thioesterase K07107 - - 0.00000001729 65.0
HKD2_k127_7709676_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.05e-221 695.0
HKD2_k127_7709676_1 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 404.0
HKD2_k127_7709676_2 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000002229 239.0
HKD2_k127_7709676_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000001008 213.0
HKD2_k127_7709676_4 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000002369 130.0
HKD2_k127_7709676_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000002069 134.0
HKD2_k127_7709676_6 Domain of unknown function (DUF1956) - - - 0.0000000000000000000000000002312 127.0
HKD2_k127_7709676_7 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000001056 104.0
HKD2_k127_7709676_8 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.000000000000002677 90.0
HKD2_k127_7732230_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 1.079e-250 787.0
HKD2_k127_7732230_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00249 - 1.3.8.7 7.874e-218 681.0
HKD2_k127_7732230_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 464.0
HKD2_k127_7732230_3 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001448 288.0
HKD2_k127_7732230_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000008071 231.0
HKD2_k127_7732230_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000001165 225.0
HKD2_k127_7732230_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000001851 155.0
HKD2_k127_7732230_7 - - - - 0.00000000000000000000000006016 118.0
HKD2_k127_7737571_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 597.0
HKD2_k127_7737571_1 Belongs to the GARS family K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 518.0
HKD2_k127_7737571_10 PQQ-like domain - - - 0.00000000000000000000000000000000000001915 160.0
HKD2_k127_7737571_11 protein-(glutamine-N5) methyltransferase activity - - - 0.000000000000000000000000000000000006867 145.0
HKD2_k127_7737571_12 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000001373 135.0
HKD2_k127_7737571_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000002615 139.0
HKD2_k127_7737571_14 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000001211 141.0
HKD2_k127_7737571_15 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000009844 120.0
HKD2_k127_7737571_16 PFAM PQQ enzyme repeat - - - 0.000000000000000005094 98.0
HKD2_k127_7737571_17 Belongs to the BolA IbaG family - - - 0.000000000000001145 83.0
HKD2_k127_7737571_18 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000165 57.0
HKD2_k127_7737571_19 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.00002472 53.0
HKD2_k127_7737571_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 484.0
HKD2_k127_7737571_3 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 471.0
HKD2_k127_7737571_4 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 446.0
HKD2_k127_7737571_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 375.0
HKD2_k127_7737571_6 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 311.0
HKD2_k127_7737571_7 Including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000001156 201.0
HKD2_k127_7737571_8 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000002126 195.0
HKD2_k127_7737571_9 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000744 173.0
HKD2_k127_7748122_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 425.0
HKD2_k127_7748122_1 Tocopherol cyclase K09834 - 5.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 295.0
HKD2_k127_7748122_2 Phosphate acyltransferases K15781 - 2.3.1.51,3.1.3.3 0.000000000000000000000000000000000000000000000000003344 191.0
HKD2_k127_7748122_3 transferase activity, transferring acyl groups K03824 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000456 177.0
HKD2_k127_7748122_4 Protein of unknown function (DUF3108) - - - 0.00001675 55.0
HKD2_k127_7754246_0 acyl-CoA dehydrogenase K09456,K20035 - - 3.606e-202 647.0
HKD2_k127_7754246_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 600.0
HKD2_k127_7754246_10 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000002196 176.0
HKD2_k127_7754246_11 Ferric uptake regulator family K03711,K09825 - - 0.0000000000000000000000000001978 120.0
HKD2_k127_7754246_12 Sh3 type 3 domain protein - - - 0.00000000000000201 85.0
HKD2_k127_7754246_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 611.0
HKD2_k127_7754246_3 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 496.0
HKD2_k127_7754246_4 PFAM RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 463.0
HKD2_k127_7754246_5 2-epimerase K16213 - 5.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 449.0
HKD2_k127_7754246_6 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 461.0
HKD2_k127_7754246_7 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002543 286.0
HKD2_k127_7754246_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000001726 197.0
HKD2_k127_7754246_9 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000008949 199.0
HKD2_k127_7755516_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1074.0
HKD2_k127_7755516_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.621e-282 893.0
HKD2_k127_7755516_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 333.0
HKD2_k127_7755516_11 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 312.0
HKD2_k127_7755516_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 302.0
HKD2_k127_7755516_13 Rnd family efflux transporter mfp subunit K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 307.0
HKD2_k127_7755516_14 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000744 286.0
HKD2_k127_7755516_15 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000003021 208.0
HKD2_k127_7755516_16 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000003179 188.0
HKD2_k127_7755516_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000004697 170.0
HKD2_k127_7755516_18 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000004432 162.0
HKD2_k127_7755516_19 methyltransferase - - - 0.0000000000000000000000000000000000002769 151.0
HKD2_k127_7755516_2 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 593.0
HKD2_k127_7755516_20 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000008179 150.0
HKD2_k127_7755516_21 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000008206 117.0
HKD2_k127_7755516_22 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000001928 117.0
HKD2_k127_7755516_23 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000002054 98.0
HKD2_k127_7755516_24 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000002057 81.0
HKD2_k127_7755516_25 AAA ATPase domain - - - 0.000000000000007712 75.0
HKD2_k127_7755516_26 Evidence 5 No homology to any previously reported sequences K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000187 79.0
HKD2_k127_7755516_27 Peptidogalycan biosysnthesis/recognition K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.47 0.000000000003877 80.0
HKD2_k127_7755516_28 Flavin containing amine oxidoreductase - - - 0.0000001832 65.0
HKD2_k127_7755516_29 acetyltransferase - - - 0.0001128 53.0
HKD2_k127_7755516_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 569.0
HKD2_k127_7755516_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 520.0
HKD2_k127_7755516_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 456.0
HKD2_k127_7755516_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 443.0
HKD2_k127_7755516_7 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 404.0
HKD2_k127_7755516_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 364.0
HKD2_k127_7755516_9 Cytochrome P450 K15981 - 1.14.13.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 367.0
HKD2_k127_7768326_0 Zn-dependent metallo-hydrolase RNA specificity domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 527.0
HKD2_k127_7768326_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 428.0
HKD2_k127_7768326_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004695 261.0
HKD2_k127_7768326_3 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000001577 218.0
HKD2_k127_7768326_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000006606 64.0
HKD2_k127_7775640_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 4.886e-211 682.0
HKD2_k127_7775640_1 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 578.0
HKD2_k127_7775640_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 351.0
HKD2_k127_7775640_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000006724 237.0
HKD2_k127_7775640_4 Memo-like protein - - - 0.000000000000000000000000000000000000000000000000001268 200.0
HKD2_k127_7775640_5 cellulose binding - - - 0.00000000000000000000000000000000005814 147.0
HKD2_k127_7775640_6 MMPL family K07003 - - 0.00000000000000000000009755 104.0
HKD2_k127_7775640_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.00000000004211 70.0
HKD2_k127_7775640_8 Domain of unknown function (DUF4911) - - - 0.00008529 48.0
HKD2_k127_7784879_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 3.058e-236 764.0
HKD2_k127_7784879_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 489.0
HKD2_k127_7784879_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000005484 147.0
HKD2_k127_7784879_11 Domain of unknown function (DUF4442) K02614 - - 0.0000000000000000001883 96.0
HKD2_k127_7784879_12 Protein of unknown function (DUF2905) - - - 0.00000000000000001093 85.0
HKD2_k127_7784879_13 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0000002247 53.0
HKD2_k127_7784879_14 thiolester hydrolase activity - - - 0.000002717 61.0
HKD2_k127_7784879_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 425.0
HKD2_k127_7784879_3 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 402.0
HKD2_k127_7784879_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 384.0
HKD2_k127_7784879_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 315.0
HKD2_k127_7784879_6 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 284.0
HKD2_k127_7784879_7 Histidine kinase HAMP - - - 0.00000000000000000000000000000000000000000000000000000000001146 227.0
HKD2_k127_7784879_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000505 197.0
HKD2_k127_7784879_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000001366 184.0
HKD2_k127_7868325_0 glycosyl transferase family K00697 - 2.4.1.15,2.4.1.347 1.761e-299 936.0
HKD2_k127_7868325_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 608.0
HKD2_k127_7868325_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009783 282.0
HKD2_k127_7868325_11 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000009568 260.0
HKD2_k127_7868325_12 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000003983 216.0
HKD2_k127_7868325_13 Trehalose-phosphatase K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000004606 219.0
HKD2_k127_7868325_14 Redoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000244 205.0
HKD2_k127_7868325_15 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000158 198.0
HKD2_k127_7868325_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000195 165.0
HKD2_k127_7868325_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000002332 175.0
HKD2_k127_7868325_18 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000001334 156.0
HKD2_k127_7868325_19 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000002846 161.0
HKD2_k127_7868325_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 504.0
HKD2_k127_7868325_20 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000005339 153.0
HKD2_k127_7868325_21 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000001878 148.0
HKD2_k127_7868325_22 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000000000157 129.0
HKD2_k127_7868325_23 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000004134 128.0
HKD2_k127_7868325_24 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000001842 128.0
HKD2_k127_7868325_25 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000006619 112.0
HKD2_k127_7868325_26 Protein of unknown function (DUF1302) - - - 0.00000000000000000008618 104.0
HKD2_k127_7868325_27 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000003055 96.0
HKD2_k127_7868325_28 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000002581 81.0
HKD2_k127_7868325_29 Pfam NUDIX - - - 0.00000000000002807 78.0
HKD2_k127_7868325_3 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 455.0
HKD2_k127_7868325_30 - - - - 0.0000000009404 66.0
HKD2_k127_7868325_31 COG0530 Ca2 Na antiporter K07301 - - 0.0001335 49.0
HKD2_k127_7868325_32 AntiSigma factor - - - 0.0002104 51.0
HKD2_k127_7868325_33 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0003978 48.0
HKD2_k127_7868325_4 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 428.0
HKD2_k127_7868325_5 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 409.0
HKD2_k127_7868325_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 372.0
HKD2_k127_7868325_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 347.0
HKD2_k127_7868325_8 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 350.0
HKD2_k127_7868325_9 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 303.0
HKD2_k127_7874150_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 603.0
HKD2_k127_7874150_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00800,K04116 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 569.0
HKD2_k127_7874150_10 oxidoreductase activity, acting on CH-OH group of donors K16260 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0000000000000000000000000000000002269 140.0
HKD2_k127_7874150_12 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000004393 95.0
HKD2_k127_7874150_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000001132 86.0
HKD2_k127_7874150_14 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000001549 73.0
HKD2_k127_7874150_2 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 486.0
HKD2_k127_7874150_3 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 451.0
HKD2_k127_7874150_4 Exporters of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 463.0
HKD2_k127_7874150_5 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 422.0
HKD2_k127_7874150_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 421.0
HKD2_k127_7874150_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 341.0
HKD2_k127_7874150_8 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 350.0
HKD2_k127_7874150_9 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000002613 154.0
HKD2_k127_7897352_0 Phosphate transport regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007655 579.0
HKD2_k127_7897352_1 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 533.0
HKD2_k127_7897352_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 483.0
HKD2_k127_7897352_3 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000003415 258.0
HKD2_k127_7897352_4 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000002917 167.0
HKD2_k127_7897352_5 Domain of unknown function (DUF362) - - - 0.0000000000000003074 92.0
HKD2_k127_7929829_0 pyruvate-flavodoxin oxidoreductase activity - - - 1.475e-213 680.0
HKD2_k127_7929829_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 458.0
HKD2_k127_7929829_2 acyl-CoA transferase carnitine dehydratase K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000001177 259.0
HKD2_k127_7929829_3 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000005334 222.0
HKD2_k127_7929829_4 - - - - 0.00000006266 65.0
HKD2_k127_7946133_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.576e-274 863.0
HKD2_k127_7946133_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.254e-264 837.0
HKD2_k127_7946133_10 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 301.0
HKD2_k127_7946133_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000004495 271.0
HKD2_k127_7946133_12 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001746 254.0
HKD2_k127_7946133_13 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000001886 210.0
HKD2_k127_7946133_14 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000000000003902 196.0
HKD2_k127_7946133_15 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000002602 203.0
HKD2_k127_7946133_16 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000001335 190.0
HKD2_k127_7946133_17 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000006195 169.0
HKD2_k127_7946133_18 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000005611 158.0
HKD2_k127_7946133_19 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000002315 144.0
HKD2_k127_7946133_2 Transferase hexapeptide repeat containing protein K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 607.0
HKD2_k127_7946133_20 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006509 132.0
HKD2_k127_7946133_21 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000006604 109.0
HKD2_k127_7946133_22 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000005114 91.0
HKD2_k127_7946133_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 440.0
HKD2_k127_7946133_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 406.0
HKD2_k127_7946133_5 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 366.0
HKD2_k127_7946133_6 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 351.0
HKD2_k127_7946133_7 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 344.0
HKD2_k127_7946133_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 322.0
HKD2_k127_7946133_9 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 308.0
HKD2_k127_7947108_0 PFAM carboxyl transferase - - - 4.774e-247 771.0
HKD2_k127_7947108_1 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 494.0
HKD2_k127_7947108_10 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000002129 184.0
HKD2_k127_7947108_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000005001 155.0
HKD2_k127_7947108_12 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000005238 138.0
HKD2_k127_7947108_13 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002173 126.0
HKD2_k127_7947108_14 Tetratricopeptide repeat - - - 0.0000000000000000000000000002788 132.0
HKD2_k127_7947108_15 PFAM biotin lipoyl attachment domain-containing protein - - - 0.00000000000000000000000000928 119.0
HKD2_k127_7947108_17 Thiamine biosynthesis K03154 - - 0.0000000000000006607 81.0
HKD2_k127_7947108_18 2Fe-2S -binding domain K02192 - - 0.0000004895 55.0
HKD2_k127_7947108_19 DNA-sulfur modification-associated - - - 0.00001743 57.0
HKD2_k127_7947108_2 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 413.0
HKD2_k127_7947108_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 373.0
HKD2_k127_7947108_4 PFAM Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 368.0
HKD2_k127_7947108_5 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 313.0
HKD2_k127_7947108_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 293.0
HKD2_k127_7947108_7 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000419 252.0
HKD2_k127_7947108_8 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000006163 205.0
HKD2_k127_7947108_9 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000003322 205.0
HKD2_k127_7957746_0 Carbon starvation protein K06200 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 7.613e-285 888.0
HKD2_k127_7957746_1 Carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 292.0
HKD2_k127_7957746_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002379 273.0
HKD2_k127_8093488_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 8.398e-250 786.0
HKD2_k127_8093488_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.139e-247 775.0
HKD2_k127_8093488_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 536.0
HKD2_k127_8093488_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 413.0
HKD2_k127_8093488_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 319.0
HKD2_k127_8093488_5 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000001895 145.0
HKD2_k127_8093488_6 Biotin lipoyl attachment domain-containing protein - - - 0.00000000000001229 75.0
HKD2_k127_8093488_7 - - - - 0.00003019 51.0
HKD2_k127_8171447_0 Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 527.0
HKD2_k127_8171447_1 HD superfamily K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 462.0
HKD2_k127_8171447_10 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000005777 141.0
HKD2_k127_8171447_11 alpha-ribazole phosphatase activity K02226,K15634,K15640 - 3.1.3.73,5.4.2.12 0.0000000000000000000000000000004502 130.0
HKD2_k127_8171447_12 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000004837 83.0
HKD2_k127_8171447_13 Protein of unknown function (DUF1573) - - - 0.0000000009741 70.0
HKD2_k127_8171447_14 Smr domain - - - 0.000000008008 64.0
HKD2_k127_8171447_2 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 403.0
HKD2_k127_8171447_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 380.0
HKD2_k127_8171447_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 359.0
HKD2_k127_8171447_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 314.0
HKD2_k127_8171447_6 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 301.0
HKD2_k127_8171447_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000001719 216.0
HKD2_k127_8171447_8 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000000000005709 197.0
HKD2_k127_8171447_9 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000000000000002064 153.0
HKD2_k127_8203396_0 Large extracellular alpha-helical protein K06894 - - 0.0 1775.0
HKD2_k127_8203396_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 632.0
HKD2_k127_8203396_10 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 322.0
HKD2_k127_8203396_11 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
HKD2_k127_8203396_12 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000003715 236.0
HKD2_k127_8203396_13 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000001186 184.0
HKD2_k127_8203396_14 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000008779 156.0
HKD2_k127_8203396_15 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000036 157.0
HKD2_k127_8203396_16 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000009904 151.0
HKD2_k127_8203396_17 KR domain - - - 0.00000000000000000000000000000000000002986 155.0
HKD2_k127_8203396_18 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000157 139.0
HKD2_k127_8203396_19 ACT domain - - - 0.0000000000000000000000000001737 121.0
HKD2_k127_8203396_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 559.0
HKD2_k127_8203396_20 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000003512 114.0
HKD2_k127_8203396_21 - - - - 0.0000000000000000001332 96.0
HKD2_k127_8203396_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000001552 93.0
HKD2_k127_8203396_23 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000002891 75.0
HKD2_k127_8203396_24 PFAM regulatory protein MarR - - - 0.00000000001362 70.0
HKD2_k127_8203396_25 Heavy-metal resistance - - - 0.0000007079 57.0
HKD2_k127_8203396_26 - - - - 0.00000343 53.0
HKD2_k127_8203396_27 Heavy-metal resistance - - - 0.00005627 51.0
HKD2_k127_8203396_29 - - - - 0.0000621 48.0
HKD2_k127_8203396_3 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 521.0
HKD2_k127_8203396_4 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 474.0
HKD2_k127_8203396_5 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 417.0
HKD2_k127_8203396_6 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 419.0
HKD2_k127_8203396_7 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 411.0
HKD2_k127_8203396_8 'glutamate synthase K00123,K00317,K00528,K09835 - 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 360.0
HKD2_k127_8203396_9 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 361.0
HKD2_k127_8441664_0 PFAM transcriptional regulator domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 505.0
HKD2_k127_8441664_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 452.0
HKD2_k127_8441664_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 437.0
HKD2_k127_8441664_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 302.0
HKD2_k127_8441664_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 307.0
HKD2_k127_8441664_5 Protein involved in cellulose biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003485 276.0
HKD2_k127_8441664_6 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001786 266.0
HKD2_k127_8441664_7 ADP-glyceromanno-heptose 6-epimerase activity K01784,K20534 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000001393 203.0
HKD2_k127_8441664_8 YCII-related domain - - - 0.0000000000000000000000000000000000000000000003734 169.0
HKD2_k127_8501966_0 O-methyltransferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 484.0
HKD2_k127_8501966_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 368.0
HKD2_k127_8501966_2 - - - - 0.000000000000000000000000005692 122.0
HKD2_k127_8501966_3 SnoaL-like domain - - - 0.00000000000000000000000001373 124.0
HKD2_k127_8501966_4 - - - - 0.00004342 47.0
HKD2_k127_8571414_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 3.521e-233 736.0
HKD2_k127_8571414_1 Predicted Peptidoglycan domain K17733 - - 0.00000000000000000000000000000000000000000000000000000000000002224 233.0
HKD2_k127_8571414_2 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.00000000000000000000000000000000000000000000000000008351 208.0
HKD2_k127_8571414_3 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000002036 143.0
HKD2_k127_8571414_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000001546 131.0
HKD2_k127_8571414_5 PFAM amine oxidase K01854 - 5.4.99.9 0.000000000000000000002303 96.0
HKD2_k127_8571414_6 sh3 domain protein - - - 0.000000000002158 79.0
HKD2_k127_8696799_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.999e-267 849.0
HKD2_k127_8696799_1 Transketolase, C-terminal domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 486.0
HKD2_k127_8696799_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 468.0
HKD2_k127_8696799_3 Histone deacetylase domain K11418 - 3.5.1.98 0.000000000000000000000000000000000000000000000000000000000000000001832 237.0
HKD2_k127_8696799_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000001367 97.0
HKD2_k127_8696799_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000002919 84.0
HKD2_k127_8696799_6 - - - - 0.00000000000001271 85.0
HKD2_k127_8696799_7 alcohol dehydrogenase - - - 0.00000000000003607 75.0
HKD2_k127_88895_0 PFAM Transketolase central region K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 336.0
HKD2_k127_88895_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 262.0
HKD2_k127_88895_2 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000878 254.0
HKD2_k127_88895_3 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000004102 243.0
HKD2_k127_88895_4 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000002153 119.0
HKD2_k127_88895_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000001617 107.0
HKD2_k127_88895_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000002146 97.0
HKD2_k127_8956744_1 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000000001747 192.0
HKD2_k127_8956744_10 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00001323 47.0
HKD2_k127_8956744_2 Glycosyl transferase family 11 - - - 0.000000000000000000000000000000000000000000000000002517 196.0
HKD2_k127_8956744_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000002171 134.0
HKD2_k127_8956744_4 endoribonuclease L-PSP - - - 0.00000000000000000000000000001804 120.0
HKD2_k127_8956744_5 Belongs to the 'phage' integrase family K14059 - - 0.0000000000000000001612 96.0
HKD2_k127_8956744_7 Belongs to the 'phage' integrase family K14059 - - 0.00000002003 61.0
HKD2_k127_8956744_9 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000177 58.0
HKD2_k127_8992316_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 5.824e-252 816.0
HKD2_k127_8992316_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 2.502e-235 760.0
HKD2_k127_8992316_10 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 296.0
HKD2_k127_8992316_11 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001932 276.0
HKD2_k127_8992316_12 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005329 249.0
HKD2_k127_8992316_13 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000005436 235.0
HKD2_k127_8992316_14 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000009704 193.0
HKD2_k127_8992316_15 protein containing LysM domain - GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - 0.00000000000000000000000000000000000000000000000007637 183.0
HKD2_k127_8992316_16 Transporter Component K07112 - - 0.000000000000000000000000000000000000000001674 165.0
HKD2_k127_8992316_17 transporter component K07112 - - 0.00000000000000000000000000000000000003413 153.0
HKD2_k127_8992316_18 SnoaL-like domain - - - 0.000000000000000000000000000000000002208 143.0
HKD2_k127_8992316_19 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000009804 150.0
HKD2_k127_8992316_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 3.091e-231 749.0
HKD2_k127_8992316_20 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000006919 128.0
HKD2_k127_8992316_21 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.000000000000000000000000002866 118.0
HKD2_k127_8992316_22 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000005863 112.0
HKD2_k127_8992316_23 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000284 82.0
HKD2_k127_8992316_24 PFAM short-chain dehydrogenase reductase SDR - - - 0.000004721 57.0
HKD2_k127_8992316_3 Molydopterin dinucleotide binding domain K10700,K17050 - 1.17.99.2 6.891e-205 672.0
HKD2_k127_8992316_4 PFAM AMP-dependent synthetase and ligase K00666 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087 - 7.071e-194 615.0
HKD2_k127_8992316_5 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 625.0
HKD2_k127_8992316_6 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 565.0
HKD2_k127_8992316_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 449.0
HKD2_k127_8992316_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
HKD2_k127_8992316_9 4Fe-4S dicluster domain K17048,K17051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 395.0
HKD2_k127_8998429_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 1.833e-208 671.0
HKD2_k127_8998429_1 phosphate transport system permease protein K02038 - - 1.484e-196 647.0
HKD2_k127_8998429_2 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 438.0
HKD2_k127_8998429_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 360.0
HKD2_k127_8998429_4 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000506 242.0
HKD2_k127_8998429_5 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000002383 173.0
HKD2_k127_8998429_6 - - - - 0.00000000000000000000000000001966 134.0
HKD2_k127_900_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 7.107e-196 619.0
HKD2_k127_900_1 Alcohol dehydrogenase groes K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 546.0
HKD2_k127_900_10 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000007397 127.0
HKD2_k127_900_11 Cytochrome P460 - - - 0.0000000001653 69.0
HKD2_k127_900_2 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 419.0
HKD2_k127_900_3 NADP-dependent oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 396.0
HKD2_k127_900_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 320.0
HKD2_k127_900_5 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000001294 247.0
HKD2_k127_900_6 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000003078 230.0
HKD2_k127_900_7 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004086 228.0
HKD2_k127_900_8 ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000004474 238.0
HKD2_k127_900_9 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000007179 141.0
HKD2_k127_9001712_0 Alpha beta hydrolase K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 470.0
HKD2_k127_9001712_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 431.0
HKD2_k127_9001712_2 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 419.0
HKD2_k127_9001712_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000002466 226.0
HKD2_k127_9001712_4 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000001844 176.0
HKD2_k127_9001712_5 N-acetyltransferase K00675 - 2.3.1.118 0.0000000000000000000000000000000000001252 152.0
HKD2_k127_9001712_6 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000003277 139.0
HKD2_k127_9001712_7 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000003503 152.0
HKD2_k127_9001712_8 glycosyl transferase family 8 - - - 0.00000000000000000000000000000004068 139.0
HKD2_k127_9001712_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000003809 106.0
HKD2_k127_9012172_0 copper-translocating P-type ATPase K17686 - 3.6.3.54 0.0 1032.0
HKD2_k127_9012172_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.954e-229 722.0
HKD2_k127_9012172_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000004108 57.0
HKD2_k127_9012172_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000004712 60.0
HKD2_k127_9012172_2 Alkyl sulfatase dimerisation - - - 2.849e-214 688.0
HKD2_k127_9012172_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.533e-203 641.0
HKD2_k127_9012172_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 593.0
HKD2_k127_9012172_5 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 402.0
HKD2_k127_9012172_6 ATP synthase subunit D K02120 - - 0.000000000000000000000000000005715 134.0
HKD2_k127_9012172_7 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.000000000000000000009116 96.0
HKD2_k127_9012172_8 subunit (C K02119 - - 0.000000000000000002182 98.0
HKD2_k127_9012172_9 AMP binding - - - 0.000000000000002053 82.0
HKD2_k127_9043092_0 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 499.0
HKD2_k127_9043092_1 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 376.0
HKD2_k127_9043092_10 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000001178 173.0
HKD2_k127_9043092_11 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000005377 172.0
HKD2_k127_9043092_12 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000003865 172.0
HKD2_k127_9043092_13 Phage integrase family - - - 0.0000000000000000000000000009563 120.0
HKD2_k127_9043092_14 Parallel beta-helix repeats K12287 - - 0.000000000000000000000000132 113.0
HKD2_k127_9043092_15 - - - - 0.000228 46.0
HKD2_k127_9043092_2 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 330.0
HKD2_k127_9043092_3 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004259 269.0
HKD2_k127_9043092_4 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004749 275.0
HKD2_k127_9043092_5 Spirocyclase AveC-like - - - 0.000000000000000000000000000000000000000000000000000001314 207.0
HKD2_k127_9043092_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000001036 184.0
HKD2_k127_9043092_7 Hemerythrin HHE cation binding K07322 - - 0.00000000000000000000000000000000000000000000000284 180.0
HKD2_k127_9043092_8 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000001694 179.0
HKD2_k127_9043092_9 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000005846 182.0
HKD2_k127_9046350_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1387.0
HKD2_k127_9046350_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 4.732e-231 732.0
HKD2_k127_9046350_10 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000004907 90.0
HKD2_k127_9046350_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 438.0
HKD2_k127_9046350_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 381.0
HKD2_k127_9046350_4 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 320.0
HKD2_k127_9046350_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003863 279.0
HKD2_k127_9046350_6 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000113 246.0
HKD2_k127_9046350_7 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000003897 149.0
HKD2_k127_9046350_8 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000001434 136.0
HKD2_k127_9046350_9 - - - - 0.000000000000000000000009693 107.0
HKD2_k127_9064889_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 5.822e-227 727.0
HKD2_k127_9064889_1 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 484.0
HKD2_k127_9064889_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000008722 164.0
HKD2_k127_9064889_2 DSBA-like thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 385.0
HKD2_k127_9064889_3 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 357.0
HKD2_k127_9064889_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002916 288.0
HKD2_k127_9064889_5 TIGRFAM acetylornithine and succinylornithine aminotransferase K00821,K05830,K09251 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000007621 261.0
HKD2_k127_9064889_6 3-hydroxyacyl-coa dehydrogenase K00074 GO:0003674,GO:0003824,GO:0003857,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0008691,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000153 250.0
HKD2_k127_9064889_7 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000002802 225.0
HKD2_k127_9064889_8 enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000003633 218.0
HKD2_k127_9064889_9 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000003394 186.0
HKD2_k127_9067725_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.45e-227 712.0
HKD2_k127_9067725_1 TIGRFAM methylmalonyl-CoA mutase N-terminal domain - - - 3.041e-212 672.0
HKD2_k127_9067725_10 cobalamin binding - - - 0.000000000000000000000000000000000002839 160.0
HKD2_k127_9067725_12 Nitrile hydratase beta subunit - - - 0.0000000000000000000000000000003074 126.0
HKD2_k127_9067725_13 - - - - 0.0000000000000000000000000000187 128.0
HKD2_k127_9067725_14 Phosphotriesterase family K07048 - - 0.00004156 46.0
HKD2_k127_9067725_2 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 1.562e-209 662.0
HKD2_k127_9067725_3 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 548.0
HKD2_k127_9067725_4 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 493.0
HKD2_k127_9067725_5 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 446.0
HKD2_k127_9067725_6 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 412.0
HKD2_k127_9067725_7 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 302.0
HKD2_k127_9067725_8 PFAM Nitrile hydratase alpha K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 287.0
HKD2_k127_9067725_9 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000003311 214.0
HKD2_k127_9118151_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 402.0
HKD2_k127_9118151_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 387.0
HKD2_k127_9118151_2 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004099 273.0
HKD2_k127_9118151_3 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000498 123.0
HKD2_k127_9118151_4 Oxidoreductase FAD-binding domain K16246 - - 0.00000000000000000000000009816 119.0
HKD2_k127_9118151_5 - - - - 0.0000000004308 72.0
HKD2_k127_9118151_6 Acetyltransferase (GNAT) domain - - - 0.00003376 53.0
HKD2_k127_9124880_0 nickel-dependent hydrogenase, large subunit K06281 - 1.12.99.6 1.901e-268 837.0
HKD2_k127_9124880_1 GTP-binding protein TypA K06207 - - 1.234e-240 762.0
HKD2_k127_9124880_10 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 388.0
HKD2_k127_9124880_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 378.0
HKD2_k127_9124880_12 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 355.0
HKD2_k127_9124880_13 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 355.0
HKD2_k127_9124880_14 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 342.0
HKD2_k127_9124880_15 4 iron, 4 sulfur cluster binding K00124 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0006066,GO:0006071,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016052,GO:0019400,GO:0019405,GO:0019563,GO:0019588,GO:0019662,GO:0019751,GO:0031224,GO:0031226,GO:0042597,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046164,GO:0046174,GO:0055114,GO:0071704,GO:0071944,GO:1901575,GO:1901615,GO:1901616 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 304.0
HKD2_k127_9124880_16 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 296.0
HKD2_k127_9124880_17 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 308.0
HKD2_k127_9124880_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 258.0
HKD2_k127_9124880_19 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004734 250.0
HKD2_k127_9124880_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 508.0
HKD2_k127_9124880_20 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001395 255.0
HKD2_k127_9124880_21 COG1024 Enoyl-CoA hydratase carnithine racemase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000001083 228.0
HKD2_k127_9124880_22 YhhN family - - - 0.00000000000000000000000000000000000000000000000000000001093 207.0
HKD2_k127_9124880_23 SnoaL-like domain - - - 0.000000000000000000000000000000000000578 145.0
HKD2_k127_9124880_24 SnoaL-like domain - - - 0.0000000000000000000000000000000001259 137.0
HKD2_k127_9124880_25 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000443 138.0
HKD2_k127_9124880_26 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000002849 96.0
HKD2_k127_9124880_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 490.0
HKD2_k127_9124880_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 466.0
HKD2_k127_9124880_5 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 424.0
HKD2_k127_9124880_6 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 422.0
HKD2_k127_9124880_7 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 413.0
HKD2_k127_9124880_8 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 409.0
HKD2_k127_9124880_9 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 388.0
HKD2_k127_9157958_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 608.0
HKD2_k127_9157958_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 585.0
HKD2_k127_9157958_10 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 337.0
HKD2_k127_9157958_11 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 329.0
HKD2_k127_9157958_12 Male sterility protein K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 326.0
HKD2_k127_9157958_13 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 346.0
HKD2_k127_9157958_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 313.0
HKD2_k127_9157958_15 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007769 267.0
HKD2_k127_9157958_16 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001921 269.0
HKD2_k127_9157958_17 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
HKD2_k127_9157958_18 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000005428 259.0
HKD2_k127_9157958_19 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000002292 241.0
HKD2_k127_9157958_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 560.0
HKD2_k127_9157958_20 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
HKD2_k127_9157958_21 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001926 231.0
HKD2_k127_9157958_22 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000001238 216.0
HKD2_k127_9157958_23 Choline/ethanolamine kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000007456 218.0
HKD2_k127_9157958_24 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000004422 213.0
HKD2_k127_9157958_25 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000001056 193.0
HKD2_k127_9157958_26 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000001682 194.0
HKD2_k127_9157958_27 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000001076 194.0
HKD2_k127_9157958_28 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000005463 181.0
HKD2_k127_9157958_29 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000141 192.0
HKD2_k127_9157958_3 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 447.0
HKD2_k127_9157958_30 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000008849 179.0
HKD2_k127_9157958_31 glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000002337 193.0
HKD2_k127_9157958_32 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000002843 179.0
HKD2_k127_9157958_33 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001082 157.0
HKD2_k127_9157958_34 AMP binding - - - 0.0000000000000000000000000002692 120.0
HKD2_k127_9157958_35 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000002332 87.0
HKD2_k127_9157958_36 Glyoxalase-like domain K01759,K01849,K05606 - 4.4.1.5,5.1.99.1,5.4.99.2 0.0000000000000009501 89.0
HKD2_k127_9157958_37 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000001709 88.0
HKD2_k127_9157958_38 Protein of unknown function (DUF3426) - - - 0.000000000000038 84.0
HKD2_k127_9157958_39 Bacterial membrane protein, YfhO - - - 0.0000002176 64.0
HKD2_k127_9157958_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 439.0
HKD2_k127_9157958_40 TonB C terminal K03832 - - 0.000001013 61.0
HKD2_k127_9157958_41 SH3 domain protein - - - 0.000525 51.0
HKD2_k127_9157958_5 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 400.0
HKD2_k127_9157958_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 396.0
HKD2_k127_9157958_7 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 385.0
HKD2_k127_9157958_8 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 374.0
HKD2_k127_9157958_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 341.0
HKD2_k127_9168615_0 AMP-binding enzyme C-terminal domain K00666 - - 4.277e-221 697.0
HKD2_k127_9168615_1 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 340.0
HKD2_k127_9168615_2 3-beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.000000000000000000000000000000000000000000000000000000000000000000000005383 257.0
HKD2_k127_9168615_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004419 260.0
HKD2_k127_9168615_4 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000003381 136.0
HKD2_k127_9209265_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 435.0
HKD2_k127_9209265_1 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 373.0
HKD2_k127_9209265_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007831 271.0
HKD2_k127_9209265_3 Pfam Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001552 252.0
HKD2_k127_9209265_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000002703 217.0
HKD2_k127_9209265_5 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity K13669 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000006132 72.0
HKD2_k127_9209265_7 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.000000274 55.0
HKD2_k127_9232037_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 7.869e-319 987.0
HKD2_k127_9232037_1 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 8.939e-233 732.0
HKD2_k127_9232037_2 acyl-CoA dehydrogenase K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 365.0
HKD2_k127_9232037_3 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000669 261.0
HKD2_k127_9235163_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 6.92e-256 806.0
HKD2_k127_9235163_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 508.0
HKD2_k127_9235163_10 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000003549 230.0
HKD2_k127_9235163_11 Protein of unknown function (DUF1134) - - - 0.00000000000000000000000000000000000000000000000000000003295 205.0
HKD2_k127_9235163_12 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000002429 182.0
HKD2_k127_9235163_13 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000004352 181.0
HKD2_k127_9235163_14 Glycine zipper - - - 0.00000000000000000000000000000000000005745 155.0
HKD2_k127_9235163_15 response to copper ion K07156,K14166 - - 0.00000000000000000000000000000000001858 141.0
HKD2_k127_9235163_16 carbon dioxide binding K04653,K04654 - - 0.0000000000000000000000000000000005312 134.0
HKD2_k127_9235163_17 nickel cation binding K04651 - - 0.000000000000000000000001419 109.0
HKD2_k127_9235163_2 copper resistance K07245,K14166 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 507.0
HKD2_k127_9235163_3 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 481.0
HKD2_k127_9235163_4 FAD dependent oxidoreductase K15736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 446.0
HKD2_k127_9235163_5 oxidoreductases (related to aryl-alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 425.0
HKD2_k127_9235163_6 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 392.0
HKD2_k127_9235163_7 Acetyl-CoA hydrolase/transferase C-terminal domain K18288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 384.0
HKD2_k127_9235163_8 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 378.0
HKD2_k127_9235163_9 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
HKD2_k127_9241351_0 (ABC) transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 556.0
HKD2_k127_9241351_1 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 473.0
HKD2_k127_9241351_10 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 294.0
HKD2_k127_9241351_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 295.0
HKD2_k127_9241351_12 PFAM Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001839 276.0
HKD2_k127_9241351_13 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000003188 266.0
HKD2_k127_9241351_14 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007614 250.0
HKD2_k127_9241351_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000002076 239.0
HKD2_k127_9241351_16 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000001688 233.0
HKD2_k127_9241351_17 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000003338 229.0
HKD2_k127_9241351_18 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000009259 221.0
HKD2_k127_9241351_19 CcmB protein K02194 - - 0.000000000000000000000000000000000000000000000000006251 190.0
HKD2_k127_9241351_2 ABC-type multidrug transport system ATPase and permease K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 439.0
HKD2_k127_9241351_20 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000008786 191.0
HKD2_k127_9241351_21 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000002472 169.0
HKD2_k127_9241351_22 NlpC/P60 family K19224,K21471 - - 0.00000000000000000000000000000008204 134.0
HKD2_k127_9241351_23 Domain of unknown function (DUF309) K09763 - - 0.000000000000000000000000007598 119.0
HKD2_k127_9241351_24 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000008218 89.0
HKD2_k127_9241351_25 YCII-related domain K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000003269 90.0
HKD2_k127_9241351_26 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000000007283 79.0
HKD2_k127_9241351_27 - - - - 0.0000000001862 72.0
HKD2_k127_9241351_28 - - - - 0.000001302 55.0
HKD2_k127_9241351_3 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 416.0
HKD2_k127_9241351_4 ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 409.0
HKD2_k127_9241351_5 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 392.0
HKD2_k127_9241351_6 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
HKD2_k127_9241351_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 308.0
HKD2_k127_9241351_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 315.0
HKD2_k127_9241351_9 ATPases associated with a variety of cellular activities K05847 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 297.0
HKD2_k127_92641_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1472.0
HKD2_k127_92641_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.252e-219 687.0
HKD2_k127_92641_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 308.0
HKD2_k127_92641_11 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000002972 238.0
HKD2_k127_92641_12 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000002188 233.0
HKD2_k127_92641_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000002446 226.0
HKD2_k127_92641_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000001558 194.0
HKD2_k127_92641_15 Uridine 5'-monophosphate synthase K13421 GO:0003674,GO:0003824,GO:0004588,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000002354 168.0
HKD2_k127_92641_16 Isochorismatase family - - - 0.00000000000000000000000000000000000007841 151.0
HKD2_k127_92641_17 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000835 141.0
HKD2_k127_92641_18 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000008799 140.0
HKD2_k127_92641_19 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000002727 139.0
HKD2_k127_92641_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.017e-211 687.0
HKD2_k127_92641_20 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000281 121.0
HKD2_k127_92641_21 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000004074 86.0
HKD2_k127_92641_3 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 568.0
HKD2_k127_92641_4 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 511.0
HKD2_k127_92641_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 505.0
HKD2_k127_92641_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 483.0
HKD2_k127_92641_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 413.0
HKD2_k127_92641_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
HKD2_k127_92641_9 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 321.0
HKD2_k127_9272528_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.689e-290 923.0
HKD2_k127_9272528_1 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 514.0
HKD2_k127_9272528_10 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007785 271.0
HKD2_k127_9272528_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000559 264.0
HKD2_k127_9272528_12 lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000002902 254.0
HKD2_k127_9272528_13 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000885 229.0
HKD2_k127_9272528_14 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000001506 233.0
HKD2_k127_9272528_15 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.00000000000000000000000000000000000000000000002915 182.0
HKD2_k127_9272528_16 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000006429 152.0
HKD2_k127_9272528_17 FabA-like domain - - - 0.000000000000000000000000000000003174 143.0
HKD2_k127_9272528_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000001095 142.0
HKD2_k127_9272528_19 Pyruvate formate lyase-like K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000344 117.0
HKD2_k127_9272528_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 482.0
HKD2_k127_9272528_20 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000003051 109.0
HKD2_k127_9272528_21 - - - - 0.000000000000002921 81.0
HKD2_k127_9272528_22 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000002654 79.0
HKD2_k127_9272528_23 Domain of unknown function (DUF374) K09778 - - 0.0000000002274 70.0
HKD2_k127_9272528_24 - - - - 0.000000003639 67.0
HKD2_k127_9272528_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 474.0
HKD2_k127_9272528_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 406.0
HKD2_k127_9272528_5 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 343.0
HKD2_k127_9272528_6 lipid A export permease ATP-binding protein MsbA K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 342.0
HKD2_k127_9272528_7 KR domain K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 301.0
HKD2_k127_9272528_8 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 299.0
HKD2_k127_9272528_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000006679 269.0
HKD2_k127_9278984_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1178.0
HKD2_k127_9278984_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.443e-312 967.0
HKD2_k127_9278984_10 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000002918 206.0
HKD2_k127_9278984_11 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000008179 201.0
HKD2_k127_9278984_12 GAF domain - - - 0.000000000000000000000000000000000000000000000000001626 205.0
HKD2_k127_9278984_13 phosphate transporter K03306 - - 0.00000000000000000000000000000000002051 137.0
HKD2_k127_9278984_14 - - - - 0.0000000000000002315 94.0
HKD2_k127_9278984_15 Kazal type serine protease inhibitors - - - 0.00000000002393 72.0
HKD2_k127_9278984_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 6.958e-230 722.0
HKD2_k127_9278984_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.698e-226 726.0
HKD2_k127_9278984_4 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 467.0
HKD2_k127_9278984_5 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 423.0
HKD2_k127_9278984_6 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 365.0
HKD2_k127_9278984_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 329.0
HKD2_k127_9278984_8 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003083 262.0
HKD2_k127_9278984_9 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000002219 224.0
HKD2_k127_9299750_0 PFAM Type II secretion system protein E K02454 - - 2.444e-202 645.0
HKD2_k127_9299750_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K02302,K02303,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 512.0
HKD2_k127_9299750_10 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000005832 168.0
HKD2_k127_9299750_11 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000000000004654 155.0
HKD2_k127_9299750_12 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000005027 147.0
HKD2_k127_9299750_13 General secretion pathway protein C K02452 - - 0.0000000000000000000000000000000000008427 151.0
HKD2_k127_9299750_14 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000003493 122.0
HKD2_k127_9299750_15 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000001707 127.0
HKD2_k127_9299750_16 Aminoglycoside 3-N-acetyltransferase K00662 - 2.3.1.81 0.0000000000000000000000007198 115.0
HKD2_k127_9299750_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000006187 91.0
HKD2_k127_9299750_19 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000003934 79.0
HKD2_k127_9299750_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 464.0
HKD2_k127_9299750_20 Type II secretion system (T2SS), protein J K02459 - - 0.0000001254 63.0
HKD2_k127_9299750_21 Belongs to the peptidase S8 family - - - 0.0000002955 63.0
HKD2_k127_9299750_22 General secretion pathway protein K K02460 - - 0.0009561 48.0
HKD2_k127_9299750_3 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 429.0
HKD2_k127_9299750_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 426.0
HKD2_k127_9299750_5 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 427.0
HKD2_k127_9299750_6 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 399.0
HKD2_k127_9299750_7 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 389.0
HKD2_k127_9299750_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001619 284.0
HKD2_k127_9299750_9 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000001016 204.0
HKD2_k127_9300216_0 B12 binding domain - - - 2.935e-275 853.0
HKD2_k127_9300216_1 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027,K14205 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.2.3 3.095e-251 802.0
HKD2_k127_9300216_10 AMP-binding enzyme K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 533.0
HKD2_k127_9300216_11 Pyridoxal-dependent decarboxylase conserved domain K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 521.0
HKD2_k127_9300216_12 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 488.0
HKD2_k127_9300216_13 lipoprotein localization to outer membrane K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 483.0
HKD2_k127_9300216_14 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 478.0
HKD2_k127_9300216_15 lipoprotein involved in nitrous oxide reduction K21601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 433.0
HKD2_k127_9300216_16 unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 387.0
HKD2_k127_9300216_17 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 385.0
HKD2_k127_9300216_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 380.0
HKD2_k127_9300216_19 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 318.0
HKD2_k127_9300216_2 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 2.222e-222 717.0
HKD2_k127_9300216_20 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 315.0
HKD2_k127_9300216_21 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 303.0
HKD2_k127_9300216_22 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006876 255.0
HKD2_k127_9300216_23 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000004506 239.0
HKD2_k127_9300216_24 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000000000000000000000006249 248.0
HKD2_k127_9300216_25 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000001298 194.0
HKD2_k127_9300216_26 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000258 190.0
HKD2_k127_9300216_27 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000003909 183.0
HKD2_k127_9300216_28 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000005757 179.0
HKD2_k127_9300216_29 carboxylic ester hydrolase activity K08680 - 4.2.99.20 0.00000000000000000000000000000000000000001278 173.0
HKD2_k127_9300216_3 Hydantoinase B/oxoprolinase - - - 5.367e-220 705.0
HKD2_k127_9300216_30 - - - - 0.0000000000000000000000000000000000003586 148.0
HKD2_k127_9300216_31 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000002889 150.0
HKD2_k127_9300216_32 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000008024 134.0
HKD2_k127_9300216_33 - - - - 0.000000000000000000000153 100.0
HKD2_k127_9300216_34 RNA recognition motif - - - 0.0000000000000000000002158 100.0
HKD2_k127_9300216_35 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.00000000000000002964 89.0
HKD2_k127_9300216_36 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000001097 53.0
HKD2_k127_9300216_37 Ketosteroid isomerase-related protein - - - 0.000000149 59.0
HKD2_k127_9300216_38 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000003425 63.0
HKD2_k127_9300216_4 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 1.305e-205 663.0
HKD2_k127_9300216_5 HAMP domain K11383 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 612.0
HKD2_k127_9300216_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 581.0
HKD2_k127_9300216_7 Response regulator, receiver K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 583.0
HKD2_k127_9300216_8 Epoxide hydrolase N terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 563.0
HKD2_k127_9300216_9 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 522.0
HKD2_k127_9320372_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 8.597e-220 700.0
HKD2_k127_9320372_1 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 616.0
HKD2_k127_9320372_10 COG3119 Arylsulfatase A and related enzymes K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 351.0
HKD2_k127_9320372_11 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 329.0
HKD2_k127_9320372_12 Belongs to the glycosyl hydrolase 18 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 341.0
HKD2_k127_9320372_13 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 317.0
HKD2_k127_9320372_14 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008482 297.0
HKD2_k127_9320372_15 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005123 287.0
HKD2_k127_9320372_16 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002112 279.0
HKD2_k127_9320372_17 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000003963 232.0
HKD2_k127_9320372_18 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000008693 196.0
HKD2_k127_9320372_19 Amino-transferase class IV K00824,K00826 - 2.6.1.21,2.6.1.42 0.000000000000000000000000000000000000000000000078 184.0
HKD2_k127_9320372_2 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 555.0
HKD2_k127_9320372_20 - - - - 0.000000000000000000000000000000000000000000001391 169.0
HKD2_k127_9320372_21 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000817 180.0
HKD2_k127_9320372_22 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000005427 164.0
HKD2_k127_9320372_23 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000003099 123.0
HKD2_k127_9320372_24 - - - - 0.000000000000000000000000006572 117.0
HKD2_k127_9320372_25 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000002218 110.0
HKD2_k127_9320372_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000009749 98.0
HKD2_k127_9320372_27 Glycosyl transferase 4-like - - - 0.0000000000000000009678 100.0
HKD2_k127_9320372_28 - - - - 0.000000000002394 76.0
HKD2_k127_9320372_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 486.0
HKD2_k127_9320372_30 Belongs to the RimK family K05844 - - 0.00001284 57.0
HKD2_k127_9320372_31 BON domain - - - 0.00003134 48.0
HKD2_k127_9320372_32 polysaccharide deacetylase - - - 0.00003667 52.0
HKD2_k127_9320372_4 elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 468.0
HKD2_k127_9320372_5 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 441.0
HKD2_k127_9320372_6 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 433.0
HKD2_k127_9320372_7 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 427.0
HKD2_k127_9320372_8 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 397.0
HKD2_k127_9320372_9 Dehydratase K18290 - 4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 374.0
HKD2_k127_9372603_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K18307 - - 4.115e-289 918.0
HKD2_k127_9372603_1 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 4.075e-264 829.0
HKD2_k127_9372603_10 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003752 286.0
HKD2_k127_9372603_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007549 263.0
HKD2_k127_9372603_12 o-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000003521 250.0
HKD2_k127_9372603_13 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000003948 220.0
HKD2_k127_9372603_14 spore germination K16928 - - 0.000000000000000000000000000000000000000000000000000000001089 209.0
HKD2_k127_9372603_15 - - - - 0.000000000000000000000000000000000000000000000000000000292 218.0
HKD2_k127_9372603_16 Inosine-uridine preferring nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.00000000000000000000000000000000000000000000000001462 192.0
HKD2_k127_9372603_17 PFAM Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000001323 163.0
HKD2_k127_9372603_18 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000004376 159.0
HKD2_k127_9372603_19 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000001917 159.0
HKD2_k127_9372603_2 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 593.0
HKD2_k127_9372603_20 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.000000000000000000000000000000000006077 140.0
HKD2_k127_9372603_21 ABC-type Cobalt transport system, permease K16785 - - 0.000000000000000000000000000000000009468 154.0
HKD2_k127_9372603_22 transcriptional regulator, Rrf2 family K13643 - - 0.00000000000000003888 91.0
HKD2_k127_9372603_24 Pfam:DUF385 - - - 0.000001777 56.0
HKD2_k127_9372603_25 CAAX protease self-immunity K07052 - - 0.000002933 58.0
HKD2_k127_9372603_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 541.0
HKD2_k127_9372603_4 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 510.0
HKD2_k127_9372603_5 acyl-CoA dehydrogenase activity K00248,K00253 - 1.3.8.1,1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 497.0
HKD2_k127_9372603_6 acyl-CoA dehydrogenase K14448 - 1.3.8.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 453.0
HKD2_k127_9372603_7 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 380.0
HKD2_k127_9372603_8 acetyl-CoA hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 382.0
HKD2_k127_9372603_9 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 298.0
HKD2_k127_9467536_0 Coenzyme A transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 411.0
HKD2_k127_9467536_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 357.0
HKD2_k127_9467536_10 Domain of unknown function (DUF4399) - - - 0.00000000001647 65.0
HKD2_k127_9467536_11 Carotenoid biosynthesis protein - - - 0.00000008358 63.0
HKD2_k127_9467536_12 Cytochrome c K00406,K08906 - - 0.0000002329 56.0
HKD2_k127_9467536_2 Dehydrogenase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 334.0
HKD2_k127_9467536_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 333.0
HKD2_k127_9467536_4 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003004 261.0
HKD2_k127_9467536_5 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004047 245.0
HKD2_k127_9467536_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000007115 218.0
HKD2_k127_9467536_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000002534 169.0
HKD2_k127_9467536_8 phosphoglycerate mutase - - - 0.0000000000000000000000000002309 122.0
HKD2_k127_9480061_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 378.0
HKD2_k127_9480061_1 COG2211 Na melibiose symporter and related transporters K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 352.0
HKD2_k127_9480061_10 transcriptional regulator K02623,K14057 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000002627 108.0
HKD2_k127_9480061_11 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000003393 74.0
HKD2_k127_9480061_12 - - - - 0.000000001394 72.0
HKD2_k127_9480061_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 320.0
HKD2_k127_9480061_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002121 245.0
HKD2_k127_9480061_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000004825 228.0
HKD2_k127_9480061_5 protein conserved in bacteria K09793 - - 0.000000000000000000000000000000000000000000000000001034 187.0
HKD2_k127_9480061_6 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000009068 164.0
HKD2_k127_9480061_7 epimerase K18981 - 1.1.1.203 0.00000000000000000000000000000001959 137.0
HKD2_k127_9480061_8 oxidoreductase activity K02674,K07114 - - 0.00000000000000000000000000003865 133.0
HKD2_k127_9480061_9 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000003444 116.0
HKD2_k127_9506436_0 B12 binding domain K00548 - 2.1.1.13 0.0 1350.0
HKD2_k127_9506436_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 600.0
HKD2_k127_9506436_10 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 397.0
HKD2_k127_9506436_11 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 390.0
HKD2_k127_9506436_12 PFAM Major Facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 370.0
HKD2_k127_9506436_13 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 364.0
HKD2_k127_9506436_14 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 349.0
HKD2_k127_9506436_15 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 345.0
HKD2_k127_9506436_16 Flagellar biogenesis master sigma-54-dependent transcriptional response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 336.0
HKD2_k127_9506436_17 Enoyl-(Acyl carrier protein) reductase - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 314.0
HKD2_k127_9506436_18 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 310.0
HKD2_k127_9506436_19 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 306.0
HKD2_k127_9506436_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 539.0
HKD2_k127_9506436_20 Type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 320.0
HKD2_k127_9506436_21 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 304.0
HKD2_k127_9506436_22 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 297.0
HKD2_k127_9506436_23 Evidence 2b Function of strongly homologous gene K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001624 270.0
HKD2_k127_9506436_24 ErfK YbiS YcfS YnhG family protein K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004655 261.0
HKD2_k127_9506436_25 MmgE/PrpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002948 263.0
HKD2_k127_9506436_26 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000009087 239.0
HKD2_k127_9506436_27 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001134 237.0
HKD2_k127_9506436_28 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001705 238.0
HKD2_k127_9506436_29 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002724 240.0
HKD2_k127_9506436_3 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 536.0
HKD2_k127_9506436_30 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000005741 220.0
HKD2_k127_9506436_31 belongs to the thioredoxin family K03671,K05838 - - 0.00000000000000000000000000000000000000000000000000000000009314 214.0
HKD2_k127_9506436_32 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000004624 205.0
HKD2_k127_9506436_33 Smr domain - - - 0.0000000000000000000000000000000000000000000000000000001646 203.0
HKD2_k127_9506436_34 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000102 199.0
HKD2_k127_9506436_35 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000001189 190.0
HKD2_k127_9506436_36 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000001838 193.0
HKD2_k127_9506436_37 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000002034 196.0
HKD2_k127_9506436_38 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000005743 208.0
HKD2_k127_9506436_39 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000006973 195.0
HKD2_k127_9506436_4 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 494.0
HKD2_k127_9506436_40 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000002105 186.0
HKD2_k127_9506436_41 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000002944 199.0
HKD2_k127_9506436_42 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000004742 198.0
HKD2_k127_9506436_43 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000002511 183.0
HKD2_k127_9506436_44 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000946 193.0
HKD2_k127_9506436_45 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000000000002238 175.0
HKD2_k127_9506436_46 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000006303 177.0
HKD2_k127_9506436_47 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000001336 178.0
HKD2_k127_9506436_48 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000005827 171.0
HKD2_k127_9506436_49 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000001016 165.0
HKD2_k127_9506436_5 S-adenosylmethionine-dependent methyltransferase K00571,K06969,K07444,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.191,2.1.1.264,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 449.0
HKD2_k127_9506436_50 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000105 156.0
HKD2_k127_9506436_51 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000007388 160.0
HKD2_k127_9506436_52 PFAM Ig domain protein, group 1 domain protein - - - 0.0000000000000000000000000000000000003729 164.0
HKD2_k127_9506436_53 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000007914 144.0
HKD2_k127_9506436_54 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000007198 141.0
HKD2_k127_9506436_55 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000002161 124.0
HKD2_k127_9506436_56 CBS domain K04767 - - 0.00000000000000000000000000003298 124.0
HKD2_k127_9506436_57 cheY-homologous receiver domain - - - 0.0000000000000000000000000003777 120.0
HKD2_k127_9506436_58 PFAM Ig domain protein, group 1 domain protein - - - 0.000000000000000000000000002282 132.0
HKD2_k127_9506436_6 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 457.0
HKD2_k127_9506436_60 cheY-homologous receiver domain - - - 0.0000000000000000000000009747 119.0
HKD2_k127_9506436_61 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000001243 111.0
HKD2_k127_9506436_62 dehydratase - - - 0.00000000000000000000007907 109.0
HKD2_k127_9506436_63 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000002115 108.0
HKD2_k127_9506436_64 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000002467 108.0
HKD2_k127_9506436_65 Amino acid permease K03294 - - 0.0000000000000001076 84.0
HKD2_k127_9506436_66 Tetratricopeptide repeat - - - 0.0000000000000002159 93.0
HKD2_k127_9506436_67 PFAM FUN14 family - - - 0.0000000000000002549 83.0
HKD2_k127_9506436_68 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000003893 84.0
HKD2_k127_9506436_69 FecR protein - - - 0.0000000000000004468 88.0
HKD2_k127_9506436_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 436.0
HKD2_k127_9506436_70 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000486 88.0
HKD2_k127_9506436_72 rod shape-determining protein MreD K03571 - - 0.000000000001294 74.0
HKD2_k127_9506436_73 assembly protein K02665 - - 0.000000000004889 73.0
HKD2_k127_9506436_74 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0000000001371 74.0
HKD2_k127_9506436_75 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000003449 66.0
HKD2_k127_9506436_76 - - - - 0.0000007089 57.0
HKD2_k127_9506436_77 cell adhesion K05889,K17713 - 1.1.2.6 0.00001484 57.0
HKD2_k127_9506436_78 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00001833 55.0
HKD2_k127_9506436_79 - - - - 0.00006582 50.0
HKD2_k127_9506436_8 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 413.0
HKD2_k127_9506436_81 Pyridoxamine 5'-phosphate oxidase - - - 0.0002404 51.0
HKD2_k127_9506436_9 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 437.0
HKD2_k127_9810021_0 ferredoxin-NADP+ reductase activity K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 440.0
HKD2_k127_9810021_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 416.0
HKD2_k127_9810021_2 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000008615 267.0
HKD2_k127_9810021_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
HKD2_k127_9810021_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000001395 201.0
HKD2_k127_9810021_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.000000000000169 74.0
HKD2_k127_9838131_0 Fumarate reductase flavoprotein C-term K00239 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.5.1,1.3.5.4 2.231e-285 885.0
HKD2_k127_9838131_1 PFAM FAD linked oxidase domain protein K00803 - 2.5.1.26 1.057e-210 672.0
HKD2_k127_9838131_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 378.0
HKD2_k127_9838131_11 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 366.0
HKD2_k127_9838131_12 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 357.0
HKD2_k127_9838131_13 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009233 284.0
HKD2_k127_9838131_14 Proteasome subunit K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000004985 241.0
HKD2_k127_9838131_15 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000001846 227.0
HKD2_k127_9838131_16 Psort location CytoplasmicMembrane, score 10.00 K02066 - - 0.0000000000000000000000000000000000000000000000000000000000001269 221.0
HKD2_k127_9838131_17 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000002104 189.0
HKD2_k127_9838131_18 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.0000000000000000000000000000000000000000000001043 175.0
HKD2_k127_9838131_19 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000009083 132.0
HKD2_k127_9838131_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.899e-202 634.0
HKD2_k127_9838131_20 PFAM toluene tolerance K07323 - - 0.000000000000000000000000000004745 127.0
HKD2_k127_9838131_21 Zincin-like metallopeptidase - - - 0.000000000000000000000008476 115.0
HKD2_k127_9838131_22 - - - - 0.000000000000000000001282 97.0
HKD2_k127_9838131_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 592.0
HKD2_k127_9838131_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 536.0
HKD2_k127_9838131_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 503.0
HKD2_k127_9838131_6 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 499.0
HKD2_k127_9838131_7 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 486.0
HKD2_k127_9838131_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 400.0
HKD2_k127_9838131_9 Amino acid kinase family K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 390.0
HKD2_k127_991799_0 UvrD/REP helicase N-terminal domain - - - 3.278e-232 763.0
HKD2_k127_991799_1 abc transporter atp-binding protein K11085 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 472.0
HKD2_k127_991799_10 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000000000000000000000000000002259 174.0
HKD2_k127_991799_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000006331 166.0
HKD2_k127_991799_12 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000002022 158.0
HKD2_k127_991799_13 - - - - 0.00000000000000000000000007606 118.0
HKD2_k127_991799_14 - - - - 0.0000000000007698 78.0
HKD2_k127_991799_15 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000002788 70.0
HKD2_k127_991799_16 - - - - 0.00000001061 64.0
HKD2_k127_991799_17 MaoC like domain - - - 0.000007137 53.0
HKD2_k127_991799_18 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity K09709 - 4.2.1.153 0.00002588 55.0
HKD2_k127_991799_2 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 469.0
HKD2_k127_991799_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 476.0
HKD2_k127_991799_4 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 393.0
HKD2_k127_991799_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001304 285.0
HKD2_k127_991799_6 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000008264 230.0
HKD2_k127_991799_7 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000003598 219.0
HKD2_k127_991799_8 PAS domain K19694 - - 0.00000000000000000000000000000000000000000000001109 187.0
HKD2_k127_991799_9 - - - - 0.000000000000000000000000000000000000000000001142 176.0
HKD2_k127_9930409_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 604.0
HKD2_k127_9930409_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 510.0
HKD2_k127_9930409_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 413.0
HKD2_k127_9930409_3 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 417.0
HKD2_k127_9930409_4 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000001212 247.0
HKD2_k127_9930409_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000004228 215.0
HKD2_k127_9930409_6 Anion-transporting ATPase - - - 0.0000000000000000000000000000000000008628 157.0
HKD2_k127_9930409_7 Anion-transporting ATPase - - - 0.00000000000000000000000000000000008438 154.0
HKD2_k127_9930409_8 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000000832 122.0
HKD2_k127_9930409_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000001232 91.0
HKD2_k127_9939571_0 Heat shock 70 kDa protein K04043 - - 3.219e-310 961.0
HKD2_k127_9939571_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 576.0
HKD2_k127_9939571_10 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000201 276.0
HKD2_k127_9939571_11 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000002398 253.0
HKD2_k127_9939571_12 AIR synthase related protein, C-terminal domain K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000001234 234.0
HKD2_k127_9939571_13 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000006006 227.0
HKD2_k127_9939571_14 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000001018 216.0
HKD2_k127_9939571_15 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000001896 171.0
HKD2_k127_9939571_16 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000001101 152.0
HKD2_k127_9939571_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.00000000000000000000000000000029 140.0
HKD2_k127_9939571_18 Recombination protein O C terminal K03584 - - 0.0000000000000000000000000000005927 132.0
HKD2_k127_9939571_19 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000008905 123.0
HKD2_k127_9939571_2 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 563.0
HKD2_k127_9939571_20 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03749 - - 0.0001428 52.0
HKD2_k127_9939571_3 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 565.0
HKD2_k127_9939571_4 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 475.0
HKD2_k127_9939571_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 415.0
HKD2_k127_9939571_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 386.0
HKD2_k127_9939571_7 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 311.0
HKD2_k127_9939571_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 299.0
HKD2_k127_9939571_9 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 299.0
HKD2_k127_9952139_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 448.0
HKD2_k127_9952139_1 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 410.0
HKD2_k127_9952139_10 - - - - 0.0002344 52.0
HKD2_k127_9952139_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 320.0
HKD2_k127_9952139_3 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004855 292.0
HKD2_k127_9952139_4 unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001093 250.0
HKD2_k127_9952139_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000001891 200.0
HKD2_k127_9952139_6 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000002671 152.0
HKD2_k127_9952139_7 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000006132 161.0
HKD2_k127_9952139_8 Domain of unknown function (DUF4340) - - - 0.00000000007665 71.0
HKD2_k127_9952139_9 Tetratricopeptide repeat - - - 0.000001123 60.0