Overview

ID MAG01785
Name HKD2_bin.27
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Bacteroidota_A
Class UBA10030
Order UBA10030
Family UBA6906
Genus
Species
Assembly information
Completeness (%) 93.48
Contamination (%) 2.03
GC content (%) 63.0
N50 (bp) 12,794
Genome size (bp) 2,813,980

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2377

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10052548_0 ferredoxin-NADP+ reductase activity K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 402.0
HKD2_k127_10052548_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 345.0
HKD2_k127_10052548_2 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000004505 91.0
HKD2_k127_10057772_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1127.0
HKD2_k127_10057772_1 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 377.0
HKD2_k127_10057772_2 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 406.0
HKD2_k127_10057772_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007136 256.0
HKD2_k127_10057772_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000001057 243.0
HKD2_k127_10057772_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000008305 221.0
HKD2_k127_10057772_6 PD-(D/E)XK nuclease superfamily K01144,K03406,K03582,K03657,K03658,K07464,K16898,K19465 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5,3.1.12.1,3.6.4.12 0.00000000000000000000000001642 121.0
HKD2_k127_10195053_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 460.0
HKD2_k127_10195053_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002416 257.0
HKD2_k127_10195053_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004342 252.0
HKD2_k127_1026815_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 313.0
HKD2_k127_1026815_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 314.0
HKD2_k127_1026815_2 Multidrug transporter K08161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 302.0
HKD2_k127_1026815_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000004202 204.0
HKD2_k127_1026815_4 ABC-2 type transporter K01992 - - 0.000000207 60.0
HKD2_k127_1084175_0 - - - - 0.0 1660.0
HKD2_k127_1084175_1 N-Acetylmuramoyl-L-alanine amidase - - - 1.494e-303 959.0
HKD2_k127_1084175_10 - - - - 0.000000000000000000000000000000000000000004564 174.0
HKD2_k127_1084175_11 TIGRFAM universal bacterial protein YeaZ K14742 - - 0.00000000000000000000000000000000000002005 154.0
HKD2_k127_1084175_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000258 132.0
HKD2_k127_1084175_13 TRANSCRIPTIONal - - - 0.000000000000000000000000000000719 129.0
HKD2_k127_1084175_14 - - - - 0.00000000000000000000000000004675 124.0
HKD2_k127_1084175_15 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000000006728 123.0
HKD2_k127_1084175_16 rhs-related protein - - - 0.000000000000003831 89.0
HKD2_k127_1084175_2 phosphorelay signal transduction system K03413 - - 6.586e-213 672.0
HKD2_k127_1084175_4 arginyl-tRNA aminoacylation K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 5.206e-201 640.0
HKD2_k127_1084175_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 393.0
HKD2_k127_1084175_7 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 346.0
HKD2_k127_1084175_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 301.0
HKD2_k127_1084175_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000002099 232.0
HKD2_k127_123558_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 596.0
HKD2_k127_123558_1 antibiotic biosynthetic process K01434,K07116 - 3.5.1.11,3.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 602.0
HKD2_k127_123558_2 Pyruvate kinase, barrel domain K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 464.0
HKD2_k127_123558_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005665 273.0
HKD2_k127_123558_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000005099 244.0
HKD2_k127_123558_5 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001801 241.0
HKD2_k127_123558_6 - - - - 0.000000000000000000000000000000000000000000000000000000002185 214.0
HKD2_k127_123558_7 Pfam Amidohydrolase K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000005162 135.0
HKD2_k127_123558_8 antisigma factor binding K04749,K06378 - - 0.000000000000000005823 88.0
HKD2_k127_1299984_0 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 1.417e-278 882.0
HKD2_k127_1299984_1 N-Acetylmuramoyl-L-alanine amidase K01176,K01448,K06385 - 3.2.1.1,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005088 292.0
HKD2_k127_1299984_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000001128 124.0
HKD2_k127_1313264_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 331.0
HKD2_k127_1313264_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 329.0
HKD2_k127_1313264_2 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000002367 143.0
HKD2_k127_1369335_0 COG COG0383 Alpha-mannosidase - - - 1.953e-266 858.0
HKD2_k127_1369335_1 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000001797 148.0
HKD2_k127_1369335_2 Glycosyl hydrolase 38 domain protein - - - 0.0000000001621 74.0
HKD2_k127_1369335_3 PFAM Fibronectin type III domain - - - 0.000008278 59.0
HKD2_k127_1369335_4 Glycosyl hydrolases family 38 N-terminal domain - - - 0.000031 53.0
HKD2_k127_1395008_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 384.0
HKD2_k127_1395008_1 ATPase activity K01990,K13926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 341.0
HKD2_k127_1395008_2 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 315.0
HKD2_k127_1395008_3 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 310.0
HKD2_k127_1395008_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000000000000000000008236 209.0
HKD2_k127_1395008_5 outer membrane efflux protein - - - 0.00000000000000000000000000000000104 146.0
HKD2_k127_1455975_0 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 395.0
HKD2_k127_1455975_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007063 248.0
HKD2_k127_1455975_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000001665 234.0
HKD2_k127_1455975_3 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000003346 222.0
HKD2_k127_1455975_4 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000005734 196.0
HKD2_k127_145834_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 430.0
HKD2_k127_145834_1 siderophore transport K02014 - - 0.00000000000000000000000000000001227 132.0
HKD2_k127_1462252_0 mRNA catabolic process K18682 - - 2.133e-220 694.0
HKD2_k127_1462252_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.875e-205 651.0
HKD2_k127_1462252_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 585.0
HKD2_k127_1462252_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000003158 179.0
HKD2_k127_1462252_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000005258 104.0
HKD2_k127_1469425_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006501 261.0
HKD2_k127_1469425_2 histidine kinase, HAMP K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002594 225.0
HKD2_k127_1469425_3 Protein of unknown function (DUF1501) - - - 0.000000000000000000002935 109.0
HKD2_k127_1525526_0 helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 439.0
HKD2_k127_1525526_1 - - - - 0.00000000000000000000000000000000000000000008568 166.0
HKD2_k127_1525526_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.000000000000000000000000000000000000000000104 165.0
HKD2_k127_1558287_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 508.0
HKD2_k127_1558287_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 469.0
HKD2_k127_1558287_10 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000003996 139.0
HKD2_k127_1558287_11 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000002931 86.0
HKD2_k127_1558287_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000001334 57.0
HKD2_k127_1558287_2 DNA primase activity K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 459.0
HKD2_k127_1558287_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 301.0
HKD2_k127_1558287_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002715 289.0
HKD2_k127_1558287_5 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005247 283.0
HKD2_k127_1558287_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005995 250.0
HKD2_k127_1558287_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000000000000000000000002336 230.0
HKD2_k127_1558287_8 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000007573 207.0
HKD2_k127_1558287_9 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000001114 152.0
HKD2_k127_1581434_0 serine-type peptidase activity K06889,K07214 - - 7.782e-227 733.0
HKD2_k127_1581434_1 symporter activity K03307 - - 6.265e-221 696.0
HKD2_k127_1581434_2 transferase activity, transferring glycosyl groups K18785 - 2.4.1.319,2.4.1.320 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 402.0
HKD2_k127_1581434_3 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 332.0
HKD2_k127_161435_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K01876,K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.12,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 517.0
HKD2_k127_161435_1 triose-phosphate isomerase activity K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 295.0
HKD2_k127_161435_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000004548 128.0
HKD2_k127_161435_3 Belongs to the glycosyl hydrolase 2 family - - - 0.00001349 52.0
HKD2_k127_1617209_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1335.0
HKD2_k127_1617209_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 336.0
HKD2_k127_1617209_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006442 259.0
HKD2_k127_1658087_0 Concanavalin A-like lectin/glucanases superfamily - - - 9.357e-242 775.0
HKD2_k127_1658087_1 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 341.0
HKD2_k127_1658087_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000006177 237.0
HKD2_k127_165973_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 371.0
HKD2_k127_165973_1 Transposase IS200 like - - - 0.0000000000000000000000000000006863 127.0
HKD2_k127_165973_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000002953 123.0
HKD2_k127_165973_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000001376 81.0
HKD2_k127_1672036_0 galactose-1-phosphate uridylyltransferase K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 429.0
HKD2_k127_1672036_1 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000004566 86.0
HKD2_k127_1672036_2 Hemerythrin HHE cation binding domain - - - 0.00000000001914 68.0
HKD2_k127_1679295_0 beta-galactosidase activity K01190,K01195 - 3.2.1.23,3.2.1.31 1.08e-257 815.0
HKD2_k127_1679295_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 317.0
HKD2_k127_1679295_2 NHL repeat containing protein - - - 0.0000000000000000002346 93.0
HKD2_k127_1679295_3 Starch binding domain K01200 - 3.2.1.41 0.00000000000007636 78.0
HKD2_k127_1726574_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 478.0
HKD2_k127_1726574_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 464.0
HKD2_k127_1726574_2 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000002923 191.0
HKD2_k127_1726574_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000001015 156.0
HKD2_k127_1736234_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 428.0
HKD2_k127_1736234_1 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 353.0
HKD2_k127_1736234_2 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002354 280.0
HKD2_k127_1736234_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000002016 224.0
HKD2_k127_1736234_4 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000003071 118.0
HKD2_k127_1736234_5 PhoD-like phosphatase K01113 - 3.1.3.1 0.0000003212 63.0
HKD2_k127_1776572_0 Belongs to the peptidase S8 family - - - 2.221e-303 962.0
HKD2_k127_1776572_1 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 479.0
HKD2_k127_1776572_2 Binding-protein-dependent transport system inner membrane component K02025,K17322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
HKD2_k127_1776572_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 354.0
HKD2_k127_1776572_4 binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 349.0
HKD2_k127_1776572_5 alcohol dehydrogenase K17818 - 1.1.1.287 0.000000000000000001237 87.0
HKD2_k127_1776572_6 PPIC-type PPIASE domain - - - 0.000000003195 70.0
HKD2_k127_1787895_0 Glycogen debranching enzyme - - - 2.541e-225 707.0
HKD2_k127_1787895_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 452.0
HKD2_k127_1787895_10 positive regulation of growth rate - GO:0003674,GO:0005488,GO:0008150,GO:0010035,GO:0010038,GO:0030955,GO:0031420,GO:0035864,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896 - 0.00000000000000000000000000003749 121.0
HKD2_k127_1787895_11 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.00000000000000000000000002116 122.0
HKD2_k127_1787895_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 411.0
HKD2_k127_1787895_3 Belongs to the peptidase S51 family K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 336.0
HKD2_k127_1787895_4 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008922 269.0
HKD2_k127_1787895_5 - - - - 0.0000000000000000000000000000000000000000004707 169.0
HKD2_k127_1787895_6 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000009826 165.0
HKD2_k127_1787895_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000001184 158.0
HKD2_k127_1787895_8 - - - - 0.00000000000000000000000000000000001841 141.0
HKD2_k127_1787895_9 ApaG domain K06195 - - 0.00000000000000000000000000000000004545 142.0
HKD2_k127_1793596_0 beta-galactosidase activity K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 621.0
HKD2_k127_1793596_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 332.0
HKD2_k127_1793596_2 transferase activity, transferring glycosyl groups K20885 - 2.4.1.339,2.4.1.340 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 293.0
HKD2_k127_1793596_3 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.000000000000000000000000000000000000000000000000000000000000000000000000000001196 275.0
HKD2_k127_1793596_4 Pectate lyase K01142,K01728 - 3.1.11.2,4.2.2.2 0.000000000000000000321 93.0
HKD2_k127_1803918_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.267e-261 843.0
HKD2_k127_1803918_1 glutamine synthetase K01915 - 6.3.1.2 4.258e-253 786.0
HKD2_k127_1803918_2 tryptophanase activity K01667 - 4.1.99.1 3.633e-220 692.0
HKD2_k127_1803918_3 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 499.0
HKD2_k127_1803918_4 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000013 266.0
HKD2_k127_1803918_5 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000001656 237.0
HKD2_k127_1803918_6 purine ribonucleoside salvage K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000001414 216.0
HKD2_k127_1803918_7 COG1522 Transcriptional regulators K03719 - - 0.00000000000000000000000000000000000000000000000005972 182.0
HKD2_k127_1803918_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000008311 159.0
HKD2_k127_1845383_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.892e-263 827.0
HKD2_k127_1845383_1 Transketolase, pyrimidine binding domain K00167,K11381,K21417 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 402.0
HKD2_k127_1845383_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000004259 155.0
HKD2_k127_1845383_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000003887 146.0
HKD2_k127_1845383_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 400.0
HKD2_k127_1845383_3 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 367.0
HKD2_k127_1845383_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
HKD2_k127_1845383_5 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 302.0
HKD2_k127_1845383_6 cell redox homeostasis K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000102 284.0
HKD2_k127_1845383_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006373 283.0
HKD2_k127_1845383_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000003558 248.0
HKD2_k127_1845383_9 mRNA binding K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000002475 198.0
HKD2_k127_1852656_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 312.0
HKD2_k127_1852656_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000005595 190.0
HKD2_k127_1852656_2 Single-stranded-DNA-specific exonuclease K07462 - - 0.0004293 44.0
HKD2_k127_1878030_0 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
HKD2_k127_1878030_1 protein histidine kinase activity K02660 - - 0.000000000000000000007193 104.0
HKD2_k127_1878030_2 - - - - 0.0000002061 62.0
HKD2_k127_1980435_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1305.0
HKD2_k127_1980435_1 nitronate monooxygenase activity K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 366.0
HKD2_k127_1980435_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.0000000000000000000000000000000000001884 143.0
HKD2_k127_1980435_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000001015 103.0
HKD2_k127_201852_0 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 409.0
HKD2_k127_201852_1 peroxiredoxin activity K02199 - - 0.0000000000004018 73.0
HKD2_k127_201852_2 Prenyltransferase K13277 - - 0.0000002412 62.0
HKD2_k127_2086799_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.435e-275 861.0
HKD2_k127_2086799_1 GTP cyclohydrolase II activity K02858,K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 558.0
HKD2_k127_2086799_10 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000002257 132.0
HKD2_k127_2086799_11 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000001418 72.0
HKD2_k127_2086799_12 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00001999 53.0
HKD2_k127_2086799_13 PFAM VanZ family protein - - - 0.0005947 51.0
HKD2_k127_2086799_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 480.0
HKD2_k127_2086799_3 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 435.0
HKD2_k127_2086799_4 ATP synthesis coupled electron transport K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 391.0
HKD2_k127_2086799_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 387.0
HKD2_k127_2086799_6 translation initiation factor activity K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.000000000000000000000000000000000000000000000000000003749 198.0
HKD2_k127_2086799_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624 - - 0.00000000000000000000000000000000000000000000000000001089 193.0
HKD2_k127_2086799_8 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000002695 175.0
HKD2_k127_2086799_9 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000002702 166.0
HKD2_k127_2189260_0 glycoside hydrolase family 2 sugar binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 572.0
HKD2_k127_2189260_1 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 392.0
HKD2_k127_2189260_10 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000003667 127.0
HKD2_k127_2189260_2 cell wall glycoprotein biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 364.0
HKD2_k127_2189260_3 Psort location Cytoplasmic, score K01239 - 3.2.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 327.0
HKD2_k127_2189260_4 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006618 292.0
HKD2_k127_2189260_5 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006928 286.0
HKD2_k127_2189260_6 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003229 271.0
HKD2_k127_2189260_7 Flavodoxin K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001743 259.0
HKD2_k127_2189260_8 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000004382 184.0
HKD2_k127_2189260_9 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000003892 144.0
HKD2_k127_228607_0 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 591.0
HKD2_k127_228607_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 561.0
HKD2_k127_228607_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 494.0
HKD2_k127_228607_3 Domain of unknown function (DUF4922) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000689 263.0
HKD2_k127_228607_4 acetyltransferase K22441 - 2.3.1.57 0.000000000000000000000000000000005327 136.0
HKD2_k127_228607_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000003674 69.0
HKD2_k127_228607_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000008663 64.0
HKD2_k127_2387429_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 458.0
HKD2_k127_2387429_1 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002371 86.0
HKD2_k127_2387429_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000001357 69.0
HKD2_k127_2444539_0 cellulase activity K06882 - - 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
HKD2_k127_25392_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 438.0
HKD2_k127_25392_1 Aldo Keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 346.0
HKD2_k127_25392_2 Protein of unknown function (DUF1648) - - - 0.000000000000000000000000000000000000005149 151.0
HKD2_k127_2547309_0 prolyl-tRNA aminoacylation K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 445.0
HKD2_k127_2547309_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 403.0
HKD2_k127_2547309_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 351.0
HKD2_k127_2547309_3 metallopeptidase activity K07407 - 3.2.1.22 0.0008703 43.0
HKD2_k127_2550152_0 xylulokinase activity K00848,K00854 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.17,2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 580.0
HKD2_k127_2550152_1 acetate kinase activity K00925,K19697 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1,2.7.2.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 544.0
HKD2_k127_2550152_2 Class ii aldolase K01628,K03077,K11216 - 2.7.1.189,4.1.2.17,5.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 388.0
HKD2_k127_2550152_3 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 384.0
HKD2_k127_2550152_4 BMC K04025 - - 0.00000000000000000000000000000000000005808 153.0
HKD2_k127_2550152_5 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.0000000000000000000000000000000236 128.0
HKD2_k127_2550152_6 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000000000000000009915 120.0
HKD2_k127_2550152_7 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.0000000000000000000000002181 109.0
HKD2_k127_2550152_8 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000318 58.0
HKD2_k127_2576229_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002325 267.0
HKD2_k127_2576229_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000001575 165.0
HKD2_k127_2576229_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000003861 119.0
HKD2_k127_2576229_3 thiolester hydrolase activity K06889 - - 0.00000000000005373 84.0
HKD2_k127_2590925_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 4.507e-292 919.0
HKD2_k127_2590925_1 Cys Met metabolism K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 479.0
HKD2_k127_2590925_2 Cysteine synthase K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 480.0
HKD2_k127_2590925_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 421.0
HKD2_k127_2590925_4 COG1691 NCAIR mutase (PurE)-related K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001305 260.0
HKD2_k127_2590925_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000001055 211.0
HKD2_k127_2590925_6 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000000000000000000000002896 211.0
HKD2_k127_2590925_7 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.00000000000000000000000000000000000000000000005892 173.0
HKD2_k127_2590925_8 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000002984 149.0
HKD2_k127_2590925_9 Catalyzes two discrete reactions in the de novo synthesis of purines the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000315 72.0
HKD2_k127_2594190_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1706.0
HKD2_k127_2594190_1 PFAM NAD-dependent epimerase dehydratase - - - 1.691e-219 691.0
HKD2_k127_2594190_10 Predicted membrane protein (DUF2085) - - - 0.000000000000000000001907 100.0
HKD2_k127_2594190_2 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 1.312e-211 675.0
HKD2_k127_2594190_3 metalloendopeptidase activity K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 6.991e-196 629.0
HKD2_k127_2594190_4 Sulfate permease family K01673,K03321 - 4.2.1.1 2.447e-195 623.0
HKD2_k127_2594190_5 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 449.0
HKD2_k127_2594190_6 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 443.0
HKD2_k127_2594190_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 429.0
HKD2_k127_2594190_8 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000009394 200.0
HKD2_k127_2594190_9 CoA binding domain - - - 0.0000000000000000000000000003629 121.0
HKD2_k127_2599150_0 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000000000000000000000000000000000000000000000000000000003766 247.0
HKD2_k127_2599150_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000005965 214.0
HKD2_k127_2599150_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000002434 194.0
HKD2_k127_2599150_3 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000001835 158.0
HKD2_k127_2599150_4 efflux transmembrane transporter activity K02004 - - 0.0000000006724 71.0
HKD2_k127_2599150_5 ADP-ribosylglycohydrolase - - - 0.0000156 51.0
HKD2_k127_2611395_0 membrane organization K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 2.718e-253 809.0
HKD2_k127_2611395_1 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 6.871e-210 662.0
HKD2_k127_2611395_10 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000002173 108.0
HKD2_k127_2611395_11 outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000001924 68.0
HKD2_k127_2611395_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 321.0
HKD2_k127_2611395_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 316.0
HKD2_k127_2611395_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001962 272.0
HKD2_k127_2611395_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002747 273.0
HKD2_k127_2611395_6 unfolded protein binding K06142 - - 0.0000000000000000000000000000000000000000000000000086 186.0
HKD2_k127_2611395_7 - - - - 0.0000000000000000000000000000000000000000000000008798 184.0
HKD2_k127_2611395_8 YbaB/EbfC DNA-binding family K09747 - - 0.000000000000000000000000000003844 123.0
HKD2_k127_2611395_9 - - - - 0.000000000000000000000000000275 122.0
HKD2_k127_2617446_0 lipopolysaccharide transport - - - 3.131e-204 668.0
HKD2_k127_2617446_1 unfolded protein binding K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 574.0
HKD2_k127_2617446_10 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 362.0
HKD2_k127_2617446_11 iron ion homeostasis K03322,K03709,K04758 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 347.0
HKD2_k127_2617446_12 Belongs to the 'phage' integrase family K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 313.0
HKD2_k127_2617446_13 PhoQ Sensor K01768,K04769,K10914 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 322.0
HKD2_k127_2617446_14 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 324.0
HKD2_k127_2617446_15 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 302.0
HKD2_k127_2617446_16 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 296.0
HKD2_k127_2617446_17 - K01992,K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000876 241.0
HKD2_k127_2617446_18 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000001826 244.0
HKD2_k127_2617446_19 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000001832 193.0
HKD2_k127_2617446_2 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 552.0
HKD2_k127_2617446_20 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000003854 197.0
HKD2_k127_2617446_21 - - - - 0.000000000000000000000000000000000002478 152.0
HKD2_k127_2617446_22 FeoA - - - 0.000000000000000000008517 95.0
HKD2_k127_2617446_23 - - - - 0.00000000000000002419 95.0
HKD2_k127_2617446_25 Subtilase family - - - 0.000000000000005434 84.0
HKD2_k127_2617446_26 WD-40 repeat - - - 0.000000000000243 78.0
HKD2_k127_2617446_27 cellulose binding - - - 0.000000000001718 76.0
HKD2_k127_2617446_28 PFAM Septum formation initiator - - - 0.000006107 54.0
HKD2_k127_2617446_29 Protein of unknown function (DUF2892) - - - 0.0000113 55.0
HKD2_k127_2617446_3 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 477.0
HKD2_k127_2617446_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 466.0
HKD2_k127_2617446_5 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 458.0
HKD2_k127_2617446_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 410.0
HKD2_k127_2617446_7 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 407.0
HKD2_k127_2617446_8 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 389.0
HKD2_k127_2617446_9 diaminopimelate decarboxylase activity K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 383.0
HKD2_k127_2647921_1 Di-haem oxidoreductase, putative peroxidase - - - 0.0000003021 61.0
HKD2_k127_2659655_0 PFAM aspartate glutamate uridylate kinase K12524 - 1.1.1.3,2.7.2.4 9.076e-258 818.0
HKD2_k127_2659655_1 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 437.0
HKD2_k127_2659655_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
HKD2_k127_2659655_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
HKD2_k127_2659655_4 - - - - 0.000000000000000000000000000000000000000000008236 177.0
HKD2_k127_2659655_5 GYD domain - - - 0.00000000000000000000000000000000009519 135.0
HKD2_k127_2659655_6 Heavy-metal-associated domain K08364 - - 0.00000000000000000000000000692 114.0
HKD2_k127_2659655_7 nucleotide catabolic process - - - 0.000000000000000003701 96.0
HKD2_k127_2680135_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.444e-272 859.0
HKD2_k127_2680135_1 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K14660 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 555.0
HKD2_k127_2680135_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 378.0
HKD2_k127_2680135_11 [acyl-carrier-protein] S-malonyltransferase activity K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 345.0
HKD2_k127_2680135_12 fatty acid biosynthetic process K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 322.0
HKD2_k127_2680135_13 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 318.0
HKD2_k127_2680135_14 Bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 304.0
HKD2_k127_2680135_15 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 297.0
HKD2_k127_2680135_16 cyclic nucleotide binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002933 267.0
HKD2_k127_2680135_17 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000001451 255.0
HKD2_k127_2680135_18 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000001567 257.0
HKD2_k127_2680135_19 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001081 247.0
HKD2_k127_2680135_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 523.0
HKD2_k127_2680135_20 membrane organization K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000004351 248.0
HKD2_k127_2680135_21 Lamin Tail Domain - - - 0.00000000000000000000000000000000000000000000000000000000001857 230.0
HKD2_k127_2680135_22 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000006265 206.0
HKD2_k127_2680135_23 AIR carboxylase K11808 - 4.1.1.21 0.00000000000000000000000000000000000000000000000000000007896 200.0
HKD2_k127_2680135_24 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000006485 201.0
HKD2_k127_2680135_25 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001301 168.0
HKD2_k127_2680135_26 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000007723 161.0
HKD2_k127_2680135_27 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000000000004573 159.0
HKD2_k127_2680135_28 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000001244 120.0
HKD2_k127_2680135_29 phosphoenolpyruvate-dependent sugar phosphotransferase system K11189 - - 0.000000000000000000000000005453 111.0
HKD2_k127_2680135_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 524.0
HKD2_k127_2680135_30 hydrogenase maturation protease - - - 0.000000000000000000000004823 107.0
HKD2_k127_2680135_31 Protein of unknown function (DUF3276) - - - 0.000000000000000000000005786 105.0
HKD2_k127_2680135_32 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000007207 102.0
HKD2_k127_2680135_33 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000001462 104.0
HKD2_k127_2680135_34 Hydrogenase expression formation protein K04653 - - 0.0000000000000000000004586 100.0
HKD2_k127_2680135_35 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000001002 86.0
HKD2_k127_2680135_4 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 509.0
HKD2_k127_2680135_5 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
HKD2_k127_2680135_6 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 458.0
HKD2_k127_2680135_7 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 419.0
HKD2_k127_2680135_8 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 395.0
HKD2_k127_2680135_9 5-(carboxyamino)imidazole ribonucleotide synthase activity K01589 GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 399.0
HKD2_k127_2681627_0 Psort location Cytoplasmic, score K01424 - 3.5.1.1 1.29e-219 692.0
HKD2_k127_2681627_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000000000000000000005951 112.0
HKD2_k127_2681627_2 Tfp pilus assembly protein FimV - - - 0.0000000000000006517 86.0
HKD2_k127_2681627_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000783 69.0
HKD2_k127_2683842_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.252e-216 680.0
HKD2_k127_2683842_1 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 414.0
HKD2_k127_2683842_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002105 270.0
HKD2_k127_2683842_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000002 198.0
HKD2_k127_2722027_0 pyrroloquinoline quinone binding K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 404.0
HKD2_k127_2722027_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000008945 246.0
HKD2_k127_2735080_0 FAD linked oxidase domain protein K18930 - - 0.0 1067.0
HKD2_k127_2735080_1 CarboxypepD_reg-like domain - - - 7.658e-206 694.0
HKD2_k127_2735080_2 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 356.0
HKD2_k127_2735080_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 304.0
HKD2_k127_2735080_4 Thioesterase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006914 236.0
HKD2_k127_2735080_5 transglutaminase - - - 0.000000000000000000000000000009436 128.0
HKD2_k127_2760293_0 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 2.815e-218 703.0
HKD2_k127_2760293_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 512.0
HKD2_k127_2760293_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 427.0
HKD2_k127_2760293_3 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000001859 212.0
HKD2_k127_2760293_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000004561 133.0
HKD2_k127_2760293_5 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000002364 56.0
HKD2_k127_2799579_0 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000001671 103.0
HKD2_k127_2799579_1 deoxyhypusine monooxygenase activity - - - 0.000000000003442 78.0
HKD2_k127_2799579_2 Carbohydrate family 9 binding domain-like - - - 0.000000005384 58.0
HKD2_k127_2813707_0 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 615.0
HKD2_k127_2813707_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 396.0
HKD2_k127_2813707_2 isoprenoid biosynthetic process K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 385.0
HKD2_k127_2813707_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 367.0
HKD2_k127_2813707_4 protein transport K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 295.0
HKD2_k127_2813707_5 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000003837 193.0
HKD2_k127_2813707_6 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000002417 183.0
HKD2_k127_2813707_7 AMP binding - - - 0.000000000000000000000000000000000000000005953 161.0
HKD2_k127_2816458_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 7.05e-240 756.0
HKD2_k127_2816458_1 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 604.0
HKD2_k127_2816458_10 DinB superfamily - - - 0.000000000000000000000000000000001084 147.0
HKD2_k127_2816458_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000004136 98.0
HKD2_k127_2816458_12 beta-galactosidase activity K01190,K01195 - 3.2.1.23,3.2.1.31 0.000000000000001047 91.0
HKD2_k127_2816458_13 4Fe-4S binding domain - - - 0.0000008603 53.0
HKD2_k127_2816458_14 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0003824 50.0
HKD2_k127_2816458_2 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 604.0
HKD2_k127_2816458_3 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 554.0
HKD2_k127_2816458_4 ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 284.0
HKD2_k127_2816458_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001869 290.0
HKD2_k127_2816458_6 PFAM Thioredoxin domain K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007102 260.0
HKD2_k127_2816458_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000002248 163.0
HKD2_k127_2816458_8 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000000000000000004091 154.0
HKD2_k127_2816458_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15268 - - 0.0000000000000000000000000000000002462 144.0
HKD2_k127_2872853_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 400.0
HKD2_k127_2872853_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000787 249.0
HKD2_k127_2872853_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000003559 183.0
HKD2_k127_2890129_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 573.0
HKD2_k127_2890129_1 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006981 291.0
HKD2_k127_2890129_2 Asparaginase, N-terminal K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000002137 244.0
HKD2_k127_2890129_3 - - - - 0.0000000000000000000000000000000000000002455 161.0
HKD2_k127_2890129_4 positive regulation of macromolecule biosynthetic process K03973 - - 0.000001475 55.0
HKD2_k127_2908980_0 nucleotide-excision repair K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.466e-294 918.0
HKD2_k127_2908980_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 595.0
HKD2_k127_2908980_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 537.0
HKD2_k127_2908980_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000001574 194.0
HKD2_k127_2908980_4 TIGRFAM comF family protein K00764 - 2.4.2.14 0.00000000000000000000000000000000431 139.0
HKD2_k127_2908980_5 COG2202 FOG PAS PAC domain - - - 0.00000000000000000197 100.0
HKD2_k127_2934417_0 ferrous iron transmembrane transporter activity K04759 - - 1.969e-209 672.0
HKD2_k127_2934417_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 500.0
HKD2_k127_2934417_2 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000009959 216.0
HKD2_k127_2934417_3 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000004245 130.0
HKD2_k127_2934417_4 histone H1-like protein - - - 0.0000000000001056 72.0
HKD2_k127_2942293_0 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 336.0
HKD2_k127_2942293_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001393 263.0
HKD2_k127_2942293_2 Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose K06726 - 5.4.99.62 0.000000000000000000000000000000001404 134.0
HKD2_k127_2942293_3 PFAM glycoside hydrolase family 39 - - - 0.00000000000000000007264 103.0
HKD2_k127_2942293_4 Glyoxalase-like domain - - - 0.0000000000002439 77.0
HKD2_k127_2944178_0 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 3.182e-237 744.0
HKD2_k127_2944178_1 Bacterial protein of unknown function (DUF853) - - - 9.652e-207 655.0
HKD2_k127_2944178_10 PFAM cation antiporter K05569 - - 0.000000000000000000000000000000000000000000628 162.0
HKD2_k127_2944178_11 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000000001573 159.0
HKD2_k127_2944178_12 PFAM Na H antiporter MnhB subunit-related protein K05566 - - 0.000000000000000000000000000000000000002246 165.0
HKD2_k127_2944178_13 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000008284 126.0
HKD2_k127_2944178_14 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560,K05567 - - 0.0000000000000000000000000002706 117.0
HKD2_k127_2944178_15 Belongs to the P(II) protein family - - - 0.0000000000000004889 91.0
HKD2_k127_2944178_16 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000003244 76.0
HKD2_k127_2944178_17 OmpW family K07275 - - 0.0000002126 62.0
HKD2_k127_2944178_2 Domain of unknown function (DUF4040) K05559,K05565 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 618.0
HKD2_k127_2944178_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 565.0
HKD2_k127_2944178_4 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 518.0
HKD2_k127_2944178_5 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 441.0
HKD2_k127_2944178_6 Permease K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 385.0
HKD2_k127_2944178_7 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 350.0
HKD2_k127_2944178_8 PFAM regulatory protein MarR K15973 - - 0.00000000000000000000000000000000000000000000000000000556 193.0
HKD2_k127_2944178_9 YceI-like domain - - - 0.0000000000000000000000000000000000000000000001013 179.0
HKD2_k127_294483_0 PFAM Uncharacterised protein family UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 297.0
HKD2_k127_294483_1 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000002286 171.0
HKD2_k127_294483_2 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.000000000000000000000000000000003827 132.0
HKD2_k127_2951635_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.075e-299 933.0
HKD2_k127_2951635_1 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 4.013e-242 776.0
HKD2_k127_2951635_2 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002965 259.0
HKD2_k127_2951635_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000001007 182.0
HKD2_k127_2951635_4 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000008996 187.0
HKD2_k127_2971275_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 348.0
HKD2_k127_2971275_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 323.0
HKD2_k127_2971275_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005397 255.0
HKD2_k127_2988144_0 glucan 1,4-alpha-glucosidase activity K01178 - 3.2.1.3 1.343e-248 804.0
HKD2_k127_2988144_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 291.0
HKD2_k127_3003762_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.477e-285 897.0
HKD2_k127_3003762_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 2.571e-225 712.0
HKD2_k127_3003762_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000188 241.0
HKD2_k127_3003762_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000005775 147.0
HKD2_k127_3003762_4 regulation of translation K03530,K05788 - - 0.00000000000000000000000000000007639 127.0
HKD2_k127_3003762_5 gas vesicle protein - - - 0.0000000000000000000000000001509 119.0
HKD2_k127_3003762_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000136 125.0
HKD2_k127_3003762_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000009521 103.0
HKD2_k127_3003762_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000008095 76.0
HKD2_k127_3003762_9 - - - - 0.00001436 49.0
HKD2_k127_3041088_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 577.0
HKD2_k127_3041088_1 serine-type endopeptidase activity K04771,K14949 - 2.7.11.1,3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000001123 236.0
HKD2_k127_3041088_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000001961 211.0
HKD2_k127_3041088_3 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000000000000000000004238 99.0
HKD2_k127_3041088_5 - - - - 0.000000000000001074 80.0
HKD2_k127_3041088_6 - - - - 0.00000000000000504 85.0
HKD2_k127_3041088_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000004603 53.0
HKD2_k127_3063076_0 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 1.954e-268 863.0
HKD2_k127_3063076_1 Belongs to the peptidase S8 family - - - 4.922e-268 876.0
HKD2_k127_3063076_10 Sigma-70 region 2 - - - 0.0000000000000000000000000000007701 128.0
HKD2_k127_3063076_11 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000004698 66.0
HKD2_k127_3063076_2 TonB-dependent receptor - - - 6.713e-267 851.0
HKD2_k127_3063076_3 ATPase activity K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 469.0
HKD2_k127_3063076_4 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 349.0
HKD2_k127_3063076_5 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 340.0
HKD2_k127_3063076_6 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 319.0
HKD2_k127_3063076_7 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004081 283.0
HKD2_k127_3063076_8 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000001467 233.0
HKD2_k127_3063076_9 arabinogalactan endo-1,4-beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000003514 189.0
HKD2_k127_3070790_0 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 345.0
HKD2_k127_3070790_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002241 295.0
HKD2_k127_3112015_0 Carboxyl transferase domain - - - 2.663e-201 640.0
HKD2_k127_3112015_1 Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 472.0
HKD2_k127_3112015_2 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.0000000000000000000000000000000000000253 148.0
HKD2_k127_3112015_3 Biotin-requiring enzyme - - - 0.000000000000000000343 96.0
HKD2_k127_3112015_4 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000182 64.0
HKD2_k127_3169817_0 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 330.0
HKD2_k127_3169817_1 Phospholipase/Carboxylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001445 287.0
HKD2_k127_3169817_2 Outer membrane lipoprotein - - - 0.0000000000000000000000001354 124.0
HKD2_k127_3194668_0 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.0 1205.0
HKD2_k127_3194668_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 476.0
HKD2_k127_3194668_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 367.0
HKD2_k127_3205472_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 614.0
HKD2_k127_3205472_1 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 535.0
HKD2_k127_3205472_2 peptidase activity, acting on L-amino acid peptides K01187,K01448,K07752 - 3.2.1.20,3.4.17.22,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 532.0
HKD2_k127_3205472_3 cysteine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 321.0
HKD2_k127_3205472_4 nucleotide catabolic process K05996 - 3.4.17.18 0.00000000000000000000000000000000000000004021 172.0
HKD2_k127_3205472_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01776,K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20,5.1.1.3 0.0000000000000000000000000000000000000004575 153.0
HKD2_k127_3205472_6 Protein of unknown function (DUF1501) - - - 0.00000000000000000000002509 115.0
HKD2_k127_3254666_0 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 423.0
HKD2_k127_3254666_1 TIGRFAM MazG family protein K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001779 270.0
HKD2_k127_3254666_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000535 236.0
HKD2_k127_3254666_3 positive regulation of growth rate - - - 0.000000000000000000000000000000109 134.0
HKD2_k127_3254666_4 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000003596 94.0
HKD2_k127_3254666_5 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000007407 91.0
HKD2_k127_3283710_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 340.0
HKD2_k127_3283710_1 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008801 286.0
HKD2_k127_3317725_0 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 470.0
HKD2_k127_3317725_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000545 200.0
HKD2_k127_3317725_2 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000007284 167.0
HKD2_k127_3323526_0 protein transport K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 1.923e-209 659.0
HKD2_k127_3323526_1 rRNA binding K02986 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 318.0
HKD2_k127_3323526_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000001112 166.0
HKD2_k127_3323526_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000002919 151.0
HKD2_k127_3323526_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000003447 135.0
HKD2_k127_3323526_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000001005 134.0
HKD2_k127_3323526_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000003871 128.0
HKD2_k127_3323526_15 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000009612 115.0
HKD2_k127_3323526_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000003502 101.0
HKD2_k127_3323526_17 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000008195 91.0
HKD2_k127_3323526_18 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000004818 70.0
HKD2_k127_3323526_19 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000001147 67.0
HKD2_k127_3323526_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 302.0
HKD2_k127_3323526_3 rRNA binding K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005231 258.0
HKD2_k127_3323526_4 tRNA binding K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000438 250.0
HKD2_k127_3323526_5 rRNA binding K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000055 233.0
HKD2_k127_3323526_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002185 211.0
HKD2_k127_3323526_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000007374 209.0
HKD2_k127_3323526_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001351 196.0
HKD2_k127_3323526_9 rRNA binding K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000000003397 169.0
HKD2_k127_3352393_0 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 1.156e-248 783.0
HKD2_k127_3352393_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000002604 228.0
HKD2_k127_3352393_2 Surface antigen - - - 0.000000000000000000000000000000000004775 156.0
HKD2_k127_340344_0 transmembrane transporter activity K03296 - - 0.00000000000000000000000000000000002063 138.0
HKD2_k127_340344_1 - - - - 0.0002277 51.0
HKD2_k127_340344_2 Appr-1'-p processing enzyme - - - 0.0004605 44.0
HKD2_k127_3408324_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 406.0
HKD2_k127_3408324_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 344.0
HKD2_k127_3408324_2 - - - - 0.00000002101 59.0
HKD2_k127_3409269_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 501.0
HKD2_k127_3521203_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 441.0
HKD2_k127_3521203_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 385.0
HKD2_k127_3521203_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001181 256.0
HKD2_k127_3521203_3 - - - - 0.0000000000171 74.0
HKD2_k127_354354_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001909 271.0
HKD2_k127_354354_1 elongation factor G K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000005376 207.0
HKD2_k127_354354_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000002641 231.0
HKD2_k127_354354_3 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000227 192.0
HKD2_k127_354354_4 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000001215 175.0
HKD2_k127_354354_5 DNA-binding transcription factor activity - - - 0.000000000000000000000000005043 117.0
HKD2_k127_3587938_0 Pfam Glycosyl hydrolases family 38 C-terminal domain K01191 - 3.2.1.24 4.328e-260 841.0
HKD2_k127_3587938_1 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 509.0
HKD2_k127_3587938_2 radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 455.0
HKD2_k127_3587938_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000006562 280.0
HKD2_k127_3587938_4 PFAM Myo-inositol catabolism IolB domain protein K03337 - 5.3.1.30 0.00000000000000002101 88.0
HKD2_k127_3633151_0 aminopeptidase activity K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 327.0
HKD2_k127_3633151_1 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 296.0
HKD2_k127_3633151_2 Zincin-like metallopeptidase - - - 0.000000000000000000000003352 106.0
HKD2_k127_3633151_3 Protein of unknown function (DUF971) - - - 0.000000000000000000001109 98.0
HKD2_k127_3633151_5 Hemerythrin HHE cation binding domain K09155 - - 0.00000000229 65.0
HKD2_k127_3652557_0 radical SAM domain protein K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 469.0
HKD2_k127_3652557_1 Domain of unknown function (DUF4835) - - - 0.000000000000000000000000000000000000001281 160.0
HKD2_k127_3652557_2 photosystem II stabilization - - - 0.0000000000000000000000001749 116.0
HKD2_k127_3652557_3 photosystem II stabilization K02237 - - 0.000001231 61.0
HKD2_k127_3809848_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 426.0
HKD2_k127_3809848_1 PA14 domain K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 376.0
HKD2_k127_3809848_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 319.0
HKD2_k127_3809848_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000003169 193.0
HKD2_k127_3809848_4 cellulose binding - - - 0.000000000000000000000005888 112.0
HKD2_k127_3809848_5 Metallo-beta-lactamase superfamily - - - 0.00000000005294 68.0
HKD2_k127_3809848_6 Hexapeptide repeat of succinyl-transferase - - - 0.0000003567 61.0
HKD2_k127_3834021_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 476.0
HKD2_k127_3834021_1 arabinose-5-phosphate isomerase activity K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 394.0
HKD2_k127_3834021_10 cobalamin-transporting ATPase activity K02014 - - 0.000000000000000000000000000000000000000000000585 190.0
HKD2_k127_3834021_11 DinB family - - - 0.00000000000000000000000000000000000000000001151 174.0
HKD2_k127_3834021_12 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.000000000000000000000000000000000000001558 157.0
HKD2_k127_3834021_13 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000106 136.0
HKD2_k127_3834021_15 Putative regulatory protein - - - 0.00000000000000000003632 94.0
HKD2_k127_3834021_16 Helix-hairpin-helix motif K02237 - - 0.000000000000003535 83.0
HKD2_k127_3834021_17 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000009306 69.0
HKD2_k127_3834021_18 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00001551 48.0
HKD2_k127_3834021_2 lipopolysaccharide-transporting ATPase activity K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 365.0
HKD2_k127_3834021_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 359.0
HKD2_k127_3834021_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 349.0
HKD2_k127_3834021_5 3-deoxy-8-phosphooctulonate synthase activity K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 350.0
HKD2_k127_3834021_6 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000108 272.0
HKD2_k127_3834021_7 lipopolysaccharide binding K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000001695 248.0
HKD2_k127_3834021_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000002631 219.0
HKD2_k127_3834021_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0070566,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000004645 190.0
HKD2_k127_3842838_0 RHS Repeat - - - 0.000000000000000000000000000000000000000000000006802 195.0
HKD2_k127_3857546_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 382.0
HKD2_k127_3857546_1 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
HKD2_k127_3857546_2 Prephenate dehydrogenase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000007674 175.0
HKD2_k127_3857546_3 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000402 175.0
HKD2_k127_3857546_4 Tetratricopeptide repeat - - - 0.00004862 52.0
HKD2_k127_3866840_0 phosphopyruvate hydratase activity K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 1.012e-201 638.0
HKD2_k127_3866840_1 Histidine kinase - - - 5.216e-195 660.0
HKD2_k127_3866840_10 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000005693 259.0
HKD2_k127_3866840_11 Glycosyl transferase, family 9 K02841,K02843,K02847,K02849,K21003 - - 0.00000000000000000000000000000000000000000000000000000008427 211.0
HKD2_k127_3866840_12 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000001314 194.0
HKD2_k127_3866840_13 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000009262 160.0
HKD2_k127_3866840_14 cellulose binding - - - 0.00000000000000000000000005094 126.0
HKD2_k127_3866840_15 membrane transporter protein K07090 - - 0.0000000000000000002763 91.0
HKD2_k127_3866840_2 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 617.0
HKD2_k127_3866840_3 Domain of unknown function (DUF4921) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 567.0
HKD2_k127_3866840_4 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 535.0
HKD2_k127_3866840_5 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 451.0
HKD2_k127_3866840_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 447.0
HKD2_k127_3866840_7 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 434.0
HKD2_k127_3866840_8 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 407.0
HKD2_k127_3866840_9 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005375 248.0
HKD2_k127_3897157_0 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001662 280.0
HKD2_k127_3897157_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000001339 173.0
HKD2_k127_3897157_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000006031 137.0
HKD2_k127_3900375_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1294.0
HKD2_k127_3900375_1 - - - - 7.763e-198 624.0
HKD2_k127_3900375_10 rRNA (adenine-C2-)-methyltransferase activity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002776 287.0
HKD2_k127_3900375_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002814 246.0
HKD2_k127_3900375_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000006274 229.0
HKD2_k127_3900375_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000004398 226.0
HKD2_k127_3900375_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000002372 221.0
HKD2_k127_3900375_15 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000000000000000000000000003935 227.0
HKD2_k127_3900375_16 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000001239 207.0
HKD2_k127_3900375_17 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000001485 192.0
HKD2_k127_3900375_19 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000005769 146.0
HKD2_k127_3900375_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 453.0
HKD2_k127_3900375_20 membrane transporter protein K07090 - - 0.00000000000000000000000000000000444 136.0
HKD2_k127_3900375_21 zinc ion binding K06204 - - 0.000000000000000000000000000005164 126.0
HKD2_k127_3900375_22 FecR protein - - - 0.00000000000000000000000001244 119.0
HKD2_k127_3900375_23 DivIVA protein K04074,K07484 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000007208 118.0
HKD2_k127_3900375_24 membrane - - - 0.0000000000000000008876 97.0
HKD2_k127_3900375_25 - - - - 0.0000001587 63.0
HKD2_k127_3900375_26 CHAT domain - - - 0.00007514 56.0
HKD2_k127_3900375_27 Outer membrane lipoprotein - - - 0.0002664 54.0
HKD2_k127_3900375_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 412.0
HKD2_k127_3900375_4 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 386.0
HKD2_k127_3900375_5 metalloendopeptidase activity K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 360.0
HKD2_k127_3900375_6 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 327.0
HKD2_k127_3900375_7 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
HKD2_k127_3900375_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 308.0
HKD2_k127_3900375_9 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001013 284.0
HKD2_k127_3904320_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 336.0
HKD2_k127_3904320_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 297.0
HKD2_k127_3904320_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00970,K00974,K00982,K00990,K06950,K15371 - 1.1.1.3,1.4.1.2,2.7.7.19,2.7.7.42,2.7.7.59,2.7.7.72,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000006323 236.0
HKD2_k127_3907892_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.335e-240 775.0
HKD2_k127_3907892_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 273.0
HKD2_k127_3907892_2 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000007444 274.0
HKD2_k127_3907892_3 BadF BadG BcrA BcrD - GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 - 0.000000000000000000000000001257 121.0
HKD2_k127_3907892_4 membrane transporter protein K07090 - - 0.00000000000000001387 92.0
HKD2_k127_3909837_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 555.0
HKD2_k127_3909837_1 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.0000000000000000000000000000000000000000000000000000000000000007424 227.0
HKD2_k127_3909837_2 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000004489 96.0
HKD2_k127_3963122_0 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 355.0
HKD2_k127_3963122_1 Bacteriophage N4 adsorption protein B K11740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 352.0
HKD2_k127_3963122_2 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 327.0
HKD2_k127_3963122_3 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002638 247.0
HKD2_k127_3963122_4 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000002055 247.0
HKD2_k127_3963122_5 Peptidase S46 - - - 0.00000000000000000000000000000000000000000000000000000000000000000002626 236.0
HKD2_k127_3963122_6 Sigma-54 interaction domain - - - 0.000000000000000000000125 101.0
HKD2_k127_3963122_7 - - - - 0.0000000000000002914 80.0
HKD2_k127_3970159_0 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
HKD2_k127_3970159_1 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001248 252.0
HKD2_k127_3970159_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000001782 209.0
HKD2_k127_3970159_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000008127 197.0
HKD2_k127_3970159_4 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000001466 134.0
HKD2_k127_3970159_5 PASTA K01921,K03587,K08884,K12132 - 2.7.11.1,3.4.16.4,6.3.2.4 0.0000000000000000000000000000001303 134.0
HKD2_k127_3970159_6 Cytochrome c, class I K08738 - - 0.00000000000000000000000000005823 118.0
HKD2_k127_3987175_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 571.0
HKD2_k127_3987175_1 cAMP biosynthetic process K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009095 289.0
HKD2_k127_3987175_10 FeS assembly protein IscX - - - 0.00003261 50.0
HKD2_k127_3987175_11 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.0001024 46.0
HKD2_k127_3987175_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005806 282.0
HKD2_k127_3987175_3 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000006198 265.0
HKD2_k127_3987175_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000001533 226.0
HKD2_k127_3987175_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000006098 202.0
HKD2_k127_3987175_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000001366 186.0
HKD2_k127_3987175_7 protein maturation K13628 - - 0.00000000000000000000000000000000000000007279 155.0
HKD2_k127_3987175_8 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000002953 135.0
HKD2_k127_3987175_9 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000001758 140.0
HKD2_k127_3999337_0 Domain of unknown function (DUF5127) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 578.0
HKD2_k127_3999337_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000002877 187.0
HKD2_k127_4003639_0 metallocarboxypeptidase activity K14054 - - 1.417e-263 843.0
HKD2_k127_4003639_1 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 546.0
HKD2_k127_4003639_10 Protein of unknown function (DUF3592) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001305 248.0
HKD2_k127_4003639_11 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000000000000004765 206.0
HKD2_k127_4003639_12 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000009631 134.0
HKD2_k127_4003639_13 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000001453 114.0
HKD2_k127_4003639_14 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000005197 82.0
HKD2_k127_4003639_15 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.000002069 59.0
HKD2_k127_4003639_2 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 448.0
HKD2_k127_4003639_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 459.0
HKD2_k127_4003639_4 Histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 398.0
HKD2_k127_4003639_5 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 339.0
HKD2_k127_4003639_6 ABC-2 family transporter protein K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 336.0
HKD2_k127_4003639_7 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 320.0
HKD2_k127_4003639_8 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003736 295.0
HKD2_k127_4003639_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 261.0
HKD2_k127_4008126_0 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002199 262.0
HKD2_k127_4038529_0 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 3.854e-229 732.0
HKD2_k127_4038529_1 PFAM Aminotransferase class I and II K00814 - 2.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 513.0
HKD2_k127_4038529_2 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 444.0
HKD2_k127_4038529_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 400.0
HKD2_k127_4038529_4 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 327.0
HKD2_k127_4038529_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001619 242.0
HKD2_k127_4038529_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000006978 248.0
HKD2_k127_4038529_7 Two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000009571 177.0
HKD2_k127_4045848_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1251.0
HKD2_k127_4045848_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 494.0
HKD2_k127_4045848_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 440.0
HKD2_k127_4045848_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 448.0
HKD2_k127_4045848_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 417.0
HKD2_k127_4045848_5 Alpha-glucosidase K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 439.0
HKD2_k127_4045848_6 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 415.0
HKD2_k127_4045848_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001166 284.0
HKD2_k127_4045848_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000174 199.0
HKD2_k127_4045848_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000006417 137.0
HKD2_k127_4057931_0 ATP-dependent DNA helicase activity K03656,K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 327.0
HKD2_k127_4057931_1 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.00000000000000005653 90.0
HKD2_k127_4079781_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 6.748e-260 815.0
HKD2_k127_4079781_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 3.584e-216 678.0
HKD2_k127_4079781_10 cobalamin-transporting ATPase activity K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000008924 233.0
HKD2_k127_4079781_11 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K12982 - - 0.0000000000000000000000000000000000000000000000000000462 205.0
HKD2_k127_4079781_12 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000001692 182.0
HKD2_k127_4079781_13 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000009137 185.0
HKD2_k127_4079781_14 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000157 158.0
HKD2_k127_4079781_15 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000006247 159.0
HKD2_k127_4079781_16 ATP synthesis coupled electron transport K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000004379 139.0
HKD2_k127_4079781_17 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000001302 133.0
HKD2_k127_4079781_18 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000003176 115.0
HKD2_k127_4079781_19 - - - - 0.000000000000000003642 96.0
HKD2_k127_4079781_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 460.0
HKD2_k127_4079781_20 amine dehydrogenase activity - - - 0.0000000000000001049 92.0
HKD2_k127_4079781_21 Domain of unknown function (DUF4412) - - - 0.00000000005757 74.0
HKD2_k127_4079781_22 long-chain fatty acid transporting porin activity - - - 0.00000002358 58.0
HKD2_k127_4079781_3 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 442.0
HKD2_k127_4079781_4 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 419.0
HKD2_k127_4079781_5 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 359.0
HKD2_k127_4079781_6 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 302.0
HKD2_k127_4079781_7 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001218 284.0
HKD2_k127_4079781_8 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006949 263.0
HKD2_k127_4079781_9 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009437 253.0
HKD2_k127_4083970_0 iron-nicotianamine transmembrane transporter activity - - - 2.07e-260 824.0
HKD2_k127_4083970_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 411.0
HKD2_k127_4083970_2 Ser-tRNA(Ala) hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000001961 195.0
HKD2_k127_4083970_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000002739 198.0
HKD2_k127_4083970_4 response regulator, receiver - - - 0.000000000000000000000000000000000000000008619 164.0
HKD2_k127_4100936_0 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 617.0
HKD2_k127_4100936_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 582.0
HKD2_k127_4100936_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000006403 72.0
HKD2_k127_4100936_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 427.0
HKD2_k127_4100936_3 coenzyme F420 hydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 364.0
HKD2_k127_4100936_4 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 346.0
HKD2_k127_4100936_5 PFAM Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 312.0
HKD2_k127_4100936_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001181 258.0
HKD2_k127_4100936_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K06951 - - 0.00000000000000000000000000000000000000000000000000000000000000001628 229.0
HKD2_k127_4100936_8 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000003361 169.0
HKD2_k127_4100936_9 Hydrogenase maturation protease - - - 0.0000000000000000000000000006452 121.0
HKD2_k127_4104660_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 494.0
HKD2_k127_4104660_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 301.0
HKD2_k127_4104660_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009255 245.0
HKD2_k127_4108587_0 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 531.0
HKD2_k127_4108587_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 472.0
HKD2_k127_4108587_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000005213 138.0
HKD2_k127_4108587_11 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000494 121.0
HKD2_k127_4108587_12 Cold shock protein domain K03704 - - 0.00000000000000000000000004409 109.0
HKD2_k127_4108587_13 Predicted membrane protein (DUF2318) K09005 - - 0.0000000000000000000329 98.0
HKD2_k127_4108587_14 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000001248 96.0
HKD2_k127_4108587_15 Regulatory protein, FmdB family - - - 0.000000006527 60.0
HKD2_k127_4108587_16 Sporulation related domain - - - 0.00001898 57.0
HKD2_k127_4108587_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 451.0
HKD2_k127_4108587_3 nicotinamide-nucleotide amidase activity K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 408.0
HKD2_k127_4108587_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 364.0
HKD2_k127_4108587_5 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 289.0
HKD2_k127_4108587_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003002 262.0
HKD2_k127_4108587_7 response to copper ion K07156 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008653 270.0
HKD2_k127_4108587_8 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000001434 254.0
HKD2_k127_4108587_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000001322 184.0
HKD2_k127_4110053_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 552.0
HKD2_k127_4110053_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 487.0
HKD2_k127_4110053_2 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 372.0
HKD2_k127_4110053_3 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000001723 249.0
HKD2_k127_4133216_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 3.632e-218 702.0
HKD2_k127_4133216_1 Glycosyl hydrolase family 3 C-terminal domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 402.0
HKD2_k127_4133216_2 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 379.0
HKD2_k127_4133216_3 amino acid activation for nonribosomal peptide biosynthetic process K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 324.0
HKD2_k127_4133216_4 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000001564 121.0
HKD2_k127_4133216_5 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000221 84.0
HKD2_k127_4133216_6 metallopeptidase activity K01179,K01181 - 3.2.1.4,3.2.1.8 0.00000000001059 79.0
HKD2_k127_4134828_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 558.0
HKD2_k127_4134828_1 Peptidase S46 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 433.0
HKD2_k127_4134828_2 PFAM alanine dehydrogenase PNT domain protein K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 331.0
HKD2_k127_4134828_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000001747 269.0
HKD2_k127_4138772_0 purine nucleobase transmembrane transporter activity K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 557.0
HKD2_k127_4138772_1 lipopolysaccharide-transporting ATPase activity K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003334 271.0
HKD2_k127_4138772_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000004136 130.0
HKD2_k127_4208872_0 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 503.0
HKD2_k127_4208872_1 oxidoreductase activity K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 424.0
HKD2_k127_4208872_10 CHAD domain - - - 0.0000000000000001033 90.0
HKD2_k127_4208872_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 412.0
HKD2_k127_4208872_3 protein (some members contain a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 364.0
HKD2_k127_4208872_4 oxidoreductase activity K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 334.0
HKD2_k127_4208872_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000003363 184.0
HKD2_k127_4208872_6 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000005497 178.0
HKD2_k127_4208872_7 protein trimerization - - - 0.000000000000000000000000000000000000000007916 166.0
HKD2_k127_4208872_8 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.00000000000000000000000000000000000009214 155.0
HKD2_k127_4208872_9 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000007803 119.0
HKD2_k127_4218300_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 3.23e-310 975.0
HKD2_k127_4218300_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000229 223.0
HKD2_k127_4219303_0 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 413.0
HKD2_k127_4219303_1 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 398.0
HKD2_k127_4219303_2 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 334.0
HKD2_k127_4219303_3 TIGRFAM methionine biosynthesis protein MetW - - - 0.000000000000005631 78.0
HKD2_k127_4245476_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.152e-247 788.0
HKD2_k127_4245476_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 602.0
HKD2_k127_4245476_10 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 277.0
HKD2_k127_4245476_11 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001388 282.0
HKD2_k127_4245476_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000003832 238.0
HKD2_k127_4245476_13 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000002268 139.0
HKD2_k127_4245476_14 methyltransferase activity - - - 0.00000000000002835 79.0
HKD2_k127_4245476_15 amine dehydrogenase activity - - - 0.00000000005466 74.0
HKD2_k127_4245476_16 - - - - 0.0000003453 60.0
HKD2_k127_4245476_17 Putative zinc-finger - - - 0.0002579 52.0
HKD2_k127_4245476_2 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 548.0
HKD2_k127_4245476_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 527.0
HKD2_k127_4245476_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 435.0
HKD2_k127_4245476_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 399.0
HKD2_k127_4245476_6 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 387.0
HKD2_k127_4245476_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 362.0
HKD2_k127_4245476_8 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 328.0
HKD2_k127_4245476_9 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006187 285.0
HKD2_k127_4269795_0 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
HKD2_k127_4269795_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 457.0
HKD2_k127_4269795_10 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000002887 189.0
HKD2_k127_4269795_11 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.00000000000000000000000000000000000000000839 164.0
HKD2_k127_4269795_12 GDP-mannose mannosyl hydrolase activity K08310 - 3.6.1.67 0.00000000000000000000000005104 115.0
HKD2_k127_4269795_13 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000001482 102.0
HKD2_k127_4269795_14 Pfam:TPM K08988 - - 0.00000007956 58.0
HKD2_k127_4269795_2 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 443.0
HKD2_k127_4269795_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 353.0
HKD2_k127_4269795_4 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000003112 233.0
HKD2_k127_4269795_5 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000002499 230.0
HKD2_k127_4269795_6 serine-type endopeptidase activity K09973 - - 0.000000000000000000000000000000000000000000000000000000000000002654 231.0
HKD2_k127_4269795_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000002112 208.0
HKD2_k127_4269795_8 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000003973 205.0
HKD2_k127_4269795_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000332 202.0
HKD2_k127_4305955_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001943 235.0
HKD2_k127_4305955_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000005738 104.0
HKD2_k127_4305955_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000007415 107.0
HKD2_k127_4305955_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000442 69.0
HKD2_k127_4364678_0 alpha-L-rhamnosidase - - - 0.0 1183.0
HKD2_k127_4364678_1 PFAM Glycoside hydrolase, family 35 K12308 - 3.2.1.23 5.176e-250 798.0
HKD2_k127_4364678_10 PTS system, Lactose/Cellobiose specific IIB subunit K02769 - 2.7.1.202 0.000000000000000000000000002796 118.0
HKD2_k127_4364678_11 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.000000000000000000000000003019 128.0
HKD2_k127_4364678_2 PEP-utilising enzyme, N-terminal K08483,K11189,K11201 - 2.7.3.9 2.098e-205 666.0
HKD2_k127_4364678_3 C-terminal region of aryl-sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 560.0
HKD2_k127_4364678_4 Galactose mutarotase-like K01811 - 3.2.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 513.0
HKD2_k127_4364678_5 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 524.0
HKD2_k127_4364678_6 PTS system, fructose subfamily, IIC subunit K02768,K02769,K02770,K11203 - 2.7.1.202 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 454.0
HKD2_k127_4364678_7 Carbohydrate esterase, sialic acid-specific acetylesterase K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 325.0
HKD2_k127_4364678_8 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.00000000000000000000000000000000000000001746 172.0
HKD2_k127_4364678_9 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.000000000000000000000000000004931 138.0
HKD2_k127_4385845_0 4 iron, 4 sulfur cluster binding K00184 - - 0.0 1081.0
HKD2_k127_4385845_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.178e-284 900.0
HKD2_k127_4385845_10 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 376.0
HKD2_k127_4385845_11 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004912 279.0
HKD2_k127_4385845_12 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007259 299.0
HKD2_k127_4385845_13 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000753 280.0
HKD2_k127_4385845_14 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000006966 226.0
HKD2_k127_4385845_15 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000001256 202.0
HKD2_k127_4385845_16 Cytochrome c K07243 - - 0.00000000000000000000000000000000000000000000000000000004383 208.0
HKD2_k127_4385845_17 spore germination - - - 0.00000000000000000000000000000000000000000000000000000008549 206.0
HKD2_k127_4385845_18 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000001209 202.0
HKD2_k127_4385845_19 FtsZ-dependent cytokinesis - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000008384 173.0
HKD2_k127_4385845_2 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.27e-263 832.0
HKD2_k127_4385845_20 rRNA binding K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002788 126.0
HKD2_k127_4385845_21 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000002623 134.0
HKD2_k127_4385845_22 ribosomal small subunit biogenesis K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000519 98.0
HKD2_k127_4385845_23 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000918 85.0
HKD2_k127_4385845_24 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000007035 87.0
HKD2_k127_4385845_25 - - - - 0.00000003533 66.0
HKD2_k127_4385845_26 signal sequence binding - - - 0.00001716 49.0
HKD2_k127_4385845_3 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 1.594e-261 815.0
HKD2_k127_4385845_4 Polysulphide reductase, NrfD K00185 - - 1.294e-232 737.0
HKD2_k127_4385845_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 568.0
HKD2_k127_4385845_6 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 452.0
HKD2_k127_4385845_7 zinc ion transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 447.0
HKD2_k127_4385845_8 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 406.0
HKD2_k127_4385845_9 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 397.0
HKD2_k127_4416294_0 Domain of unknown function (DUF5118) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 527.0
HKD2_k127_4416294_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 367.0
HKD2_k127_4416294_2 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000003074 246.0
HKD2_k127_4534111_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.76e-269 850.0
HKD2_k127_4534111_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.588e-210 665.0
HKD2_k127_4534111_10 - - - - 0.000000000000000000000000000000000000000001367 162.0
HKD2_k127_4534111_11 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000008081 155.0
HKD2_k127_4534111_12 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000005291 151.0
HKD2_k127_4534111_13 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000001223 133.0
HKD2_k127_4534111_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA - - - 0.00000000000000000000002563 109.0
HKD2_k127_4534111_15 regulation of translation K03733,K05808,K05809 - - 0.0000000000000000504 85.0
HKD2_k127_4534111_16 Protein of unknown function (DUF494) K03747 - - 0.0005125 48.0
HKD2_k127_4534111_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 544.0
HKD2_k127_4534111_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 436.0
HKD2_k127_4534111_4 Peptidase S46 - GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 353.0
HKD2_k127_4534111_5 Domain of unknown function (DUF4153) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 349.0
HKD2_k127_4534111_6 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005248 268.0
HKD2_k127_4534111_7 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000155 246.0
HKD2_k127_4534111_8 heme binding K21471 - - 0.00000000000000000000000000000000000000000000000000000009695 209.0
HKD2_k127_4534111_9 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000005387 179.0
HKD2_k127_4535685_0 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 6.04e-246 777.0
HKD2_k127_4535685_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 2.712e-209 664.0
HKD2_k127_4535685_10 Transport permease protein K01992 - - 0.00000000000000000000000000000000000006203 150.0
HKD2_k127_4535685_11 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.00000000000000000000000000000001427 130.0
HKD2_k127_4535685_2 NAD binding K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 559.0
HKD2_k127_4535685_3 ATP synthesis coupled electron transport K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 473.0
HKD2_k127_4535685_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 417.0
HKD2_k127_4535685_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 280.0
HKD2_k127_4535685_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000128 246.0
HKD2_k127_4535685_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003021 180.0
HKD2_k127_4535685_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000006274 174.0
HKD2_k127_4535685_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000002105 149.0
HKD2_k127_4553166_0 E1-E2 ATPase K12949,K12956,K17686 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0009405,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0042221,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046688,GO:0050896,GO:0051704,GO:0071944 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 305.0
HKD2_k127_4553166_1 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000001228 223.0
HKD2_k127_4553166_2 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000234 202.0
HKD2_k127_4553166_3 DNA mismatch repair protein MutT - - - 0.0000000000000000000000000000000000001678 152.0
HKD2_k127_4553166_4 Heavy-metal-associated domain K07213 - - 0.000000000265 70.0
HKD2_k127_4553166_5 Tetratricopeptide repeat - - - 0.0005787 45.0
HKD2_k127_4563352_0 Tricorn protease C1 domain K08676 - - 0.0 1387.0
HKD2_k127_4563352_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0 1114.0
HKD2_k127_4563352_10 carboxymethylenebutenolidase activity K01061,K06889 - 3.1.1.45 0.00000000000000000003016 102.0
HKD2_k127_4563352_11 Domain of unknown function (DUF309) K09763 - - 0.00000000001414 71.0
HKD2_k127_4563352_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 404.0
HKD2_k127_4563352_3 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 387.0
HKD2_k127_4563352_4 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 318.0
HKD2_k127_4563352_5 HI0933 family K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007196 281.0
HKD2_k127_4563352_6 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000943 278.0
HKD2_k127_4563352_7 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.000000000000000000000000000000000001925 143.0
HKD2_k127_4563352_8 KR domain - - - 0.0000000000000000000000000000000002451 147.0
HKD2_k127_4563352_9 - K07112 - - 0.0000000000000000000000000000911 120.0
HKD2_k127_4652746_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.0000000000000000000000000000000000000000002116 173.0
HKD2_k127_4727566_0 DNA-directed 5'-3' RNA polymerase activity K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1934.0
HKD2_k127_4727566_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1314.0
HKD2_k127_4727566_10 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000002228 225.0
HKD2_k127_4727566_11 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000008629 217.0
HKD2_k127_4727566_12 rRNA binding K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000003985 216.0
HKD2_k127_4727566_13 tRNA binding K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000006096 220.0
HKD2_k127_4727566_14 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000002534 178.0
HKD2_k127_4727566_15 cytoplasmic translation K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000003148 172.0
HKD2_k127_4727566_16 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000004907 160.0
HKD2_k127_4727566_17 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000007984 162.0
HKD2_k127_4727566_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001945 151.0
HKD2_k127_4727566_19 rRNA binding K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006918 102.0
HKD2_k127_4727566_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1079.0
HKD2_k127_4727566_20 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000005018 78.0
HKD2_k127_4727566_21 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000003007 74.0
HKD2_k127_4727566_22 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0002425 44.0
HKD2_k127_4727566_3 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 8.384e-220 687.0
HKD2_k127_4727566_4 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 389.0
HKD2_k127_4727566_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 321.0
HKD2_k127_4727566_6 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 308.0
HKD2_k127_4727566_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001385 248.0
HKD2_k127_4727566_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000006898 235.0
HKD2_k127_4727566_9 Forms part of the polypeptide exit tunnel K02926,K16193 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000163 235.0
HKD2_k127_4730963_0 polyribonucleotide nucleotidyltransferase activity K02945,K03527,K07571,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 1.435e-247 776.0
HKD2_k127_4730963_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 441.0
HKD2_k127_4730963_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 314.0
HKD2_k127_4730963_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000006323 55.0
HKD2_k127_47564_0 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 588.0
HKD2_k127_47564_1 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 576.0
HKD2_k127_47564_10 Cupin 2, conserved barrel domain protein - - - 0.000002905 53.0
HKD2_k127_47564_2 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 502.0
HKD2_k127_47564_3 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 435.0
HKD2_k127_47564_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 392.0
HKD2_k127_47564_5 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 289.0
HKD2_k127_47564_6 Domain of unknown function (DUF1949) - - - 0.00000000000000000000000000000000000001466 151.0
HKD2_k127_47564_7 transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000007888 128.0
HKD2_k127_47564_9 - K01992 - - 0.000000000001387 80.0
HKD2_k127_4767914_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 440.0
HKD2_k127_4767914_1 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 335.0
HKD2_k127_4828062_0 Cytochrome c554 and c-prime - - - 5.017e-205 648.0
HKD2_k127_4828062_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.289e-197 625.0
HKD2_k127_4828062_10 carboxypeptidase activity K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 305.0
HKD2_k127_4828062_11 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 263.0
HKD2_k127_4828062_12 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005665 263.0
HKD2_k127_4828062_13 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009502 232.0
HKD2_k127_4828062_14 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000003511 220.0
HKD2_k127_4828062_15 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000001771 180.0
HKD2_k127_4828062_16 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000001229 171.0
HKD2_k127_4828062_17 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000005729 171.0
HKD2_k127_4828062_18 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000003097 163.0
HKD2_k127_4828062_19 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000002972 156.0
HKD2_k127_4828062_2 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 588.0
HKD2_k127_4828062_20 Cytochrome c K08738 - - 0.000000000000000000000000000001103 133.0
HKD2_k127_4828062_21 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000006659 130.0
HKD2_k127_4828062_22 methyltransferase - - - 0.00000000000000000000000000001169 126.0
HKD2_k127_4828062_23 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000002188 115.0
HKD2_k127_4828062_24 rod shape-determining protein MreD K03571 - - 0.00000000000000000004191 96.0
HKD2_k127_4828062_25 Sulfurtransferase - - - 0.0000000000000003757 84.0
HKD2_k127_4828062_26 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0001373 55.0
HKD2_k127_4828062_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 587.0
HKD2_k127_4828062_4 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 552.0
HKD2_k127_4828062_5 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 417.0
HKD2_k127_4828062_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K22110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 413.0
HKD2_k127_4828062_7 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 361.0
HKD2_k127_4828062_8 peptidoglycan glycosyltransferase activity K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 364.0
HKD2_k127_4828062_9 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 317.0
HKD2_k127_4836528_0 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K01057,K02564 GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576 3.1.1.31,3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 443.0
HKD2_k127_4836528_1 synthetase (ADP forming), alpha K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 296.0
HKD2_k127_4836528_2 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.00000000000000000000002639 109.0
HKD2_k127_4845530_0 Glycosyl hydrolases family 35 K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 453.0
HKD2_k127_4845530_1 PFAM Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 319.0
HKD2_k127_492445_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.287e-198 646.0
HKD2_k127_492445_1 Peptidase family M49 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 578.0
HKD2_k127_492445_10 Protein of unknown function (DUF4230) - - - 0.0000000000000000000000000000000000000001098 163.0
HKD2_k127_492445_11 Homocysteine S-methyltransferase K00547,K21169 - 2.1.1.10 0.000000000000000000000000000005977 126.0
HKD2_k127_492445_12 - - - - 0.000000000000000000000000021 113.0
HKD2_k127_492445_13 Protein of unknown function DUF72 - - - 0.000000000000000001801 98.0
HKD2_k127_492445_14 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000000000000749 80.0
HKD2_k127_492445_15 - - - - 0.000000000005034 73.0
HKD2_k127_492445_2 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 469.0
HKD2_k127_492445_3 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 443.0
HKD2_k127_492445_4 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 372.0
HKD2_k127_492445_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 324.0
HKD2_k127_492445_6 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 325.0
HKD2_k127_492445_7 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 275.0
HKD2_k127_492445_8 impB/mucB/samB family K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001695 248.0
HKD2_k127_492445_9 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000001981 205.0
HKD2_k127_4928174_0 ABC transporter - - - 1.601e-269 838.0
HKD2_k127_4928174_1 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 528.0
HKD2_k127_4928174_10 cellulose binding - - - 0.0000000000000001533 86.0
HKD2_k127_4928174_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 501.0
HKD2_k127_4928174_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 415.0
HKD2_k127_4928174_4 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006398 292.0
HKD2_k127_4928174_5 Belongs to the 5'-nucleotidase family K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000001277 247.0
HKD2_k127_4928174_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000001303 177.0
HKD2_k127_4928174_7 - - - - 0.0000000000000000000001591 102.0
HKD2_k127_4928174_8 Belongs to the 5'-nucleotidase family - - - 0.0000000000000000000001738 113.0
HKD2_k127_4928174_9 cheY-homologous receiver domain - - - 0.000000000000000000001637 94.0
HKD2_k127_4955302_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 473.0
HKD2_k127_4955302_1 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003639 259.0
HKD2_k127_4955302_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000005296 190.0
HKD2_k127_4955302_3 Pilus assembly protein PilX K02673 - - 0.0000000000000000000000000000000000000000000000001168 194.0
HKD2_k127_4955302_4 PFAM Fimbrial assembly family protein - - - 0.000000000000000000000000000000000000000547 167.0
HKD2_k127_4955302_5 hemolysin activation secretion protein K11016 - - 0.00000000000000000000000000000000000001038 162.0
HKD2_k127_4955302_6 - - - - 0.00000000000000000000000000000000002701 146.0
HKD2_k127_4955302_7 - - - - 0.0000000000000000000000005274 112.0
HKD2_k127_500356_0 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 409.0
HKD2_k127_500356_1 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000006497 70.0
HKD2_k127_500356_2 Belongs to the glycosyl hydrolase 31 family - - - 0.000003708 61.0
HKD2_k127_5084157_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 503.0
HKD2_k127_5084157_1 cystathionine gamma-synthase activity K01758,K01760,K01761 - 4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 501.0
HKD2_k127_5084157_2 Cytochrome C-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 473.0
HKD2_k127_5084157_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000003413 207.0
HKD2_k127_5084157_4 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000004574 209.0
HKD2_k127_5084157_5 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000000000000000001799 121.0
HKD2_k127_5084157_6 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000002235 59.0
HKD2_k127_5084157_7 heat shock protein binding - - - 0.0002543 44.0
HKD2_k127_5086622_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 523.0
HKD2_k127_5086622_1 protein TIM barrel - - - 0.0000000000000000000007207 102.0
HKD2_k127_5086622_2 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000001124 107.0
HKD2_k127_510245_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.017e-259 812.0
HKD2_k127_510245_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 542.0
HKD2_k127_510245_10 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000005882 222.0
HKD2_k127_510245_11 rRNA binding K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000004379 178.0
HKD2_k127_510245_12 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000004731 180.0
HKD2_k127_510245_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000003334 158.0
HKD2_k127_510245_14 biotin transmembrane transporter activity K03523 - - 0.000000000000000000000000000000000001671 149.0
HKD2_k127_510245_15 Peptidase M56 - - - 0.000000000000000000000000000000163 143.0
HKD2_k127_510245_16 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.000000000000000000000000001505 113.0
HKD2_k127_510245_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000006944 106.0
HKD2_k127_510245_18 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000331 109.0
HKD2_k127_510245_19 iron-sulfur cluster assembly - - - 0.000000000000000000007387 94.0
HKD2_k127_510245_2 transcription antitermination K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 508.0
HKD2_k127_510245_20 long-chain fatty acid transport protein - - - 0.00000000000000003969 86.0
HKD2_k127_510245_21 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000003091 73.0
HKD2_k127_510245_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 464.0
HKD2_k127_510245_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 416.0
HKD2_k127_510245_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000737 396.0
HKD2_k127_510245_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 396.0
HKD2_k127_510245_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006947 280.0
HKD2_k127_510245_8 Cell division ATP-binding protein ftsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000003334 250.0
HKD2_k127_510245_9 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000631 254.0
HKD2_k127_5104092_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 321.0
HKD2_k127_5104092_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000014 278.0
HKD2_k127_5104092_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007644 282.0
HKD2_k127_5104092_3 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005109 277.0
HKD2_k127_5104092_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000004911 264.0
HKD2_k127_5104092_5 PFAM Stress responsive alpha-beta barrel domain protein - - - 0.000000000000000005738 87.0
HKD2_k127_5104092_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000002746 49.0
HKD2_k127_5104092_7 COG1943 Transposase and inactivated derivatives K07491 - - 0.00002358 49.0
HKD2_k127_5127727_0 undecaprenyl-phosphate glucose phosphotransferase activity K05946,K21303 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 456.0
HKD2_k127_5127727_1 transferase activity, transferring glycosyl groups K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000078 251.0
HKD2_k127_5127727_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000001116 237.0
HKD2_k127_5127727_3 NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000001114 217.0
HKD2_k127_5131524_0 Branched-chain amino acid transport system / permease component K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 349.0
HKD2_k127_5131524_1 transport system, ATPase K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
HKD2_k127_5131524_2 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000001305 125.0
HKD2_k127_5133687_0 ATP-dependent helicase K03579 - 3.6.4.13 3.454e-245 783.0
HKD2_k127_5133687_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000006578 227.0
HKD2_k127_5133687_2 membrane - - - 0.00000000000000000000000000000000000000006884 159.0
HKD2_k127_5133687_3 deoxyhypusine monooxygenase activity - - - 0.000004811 54.0
HKD2_k127_515154_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001986 289.0
HKD2_k127_515154_1 antiporter activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000001791 244.0
HKD2_k127_515154_2 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000006339 244.0
HKD2_k127_515979_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 312.0
HKD2_k127_515979_1 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000769 224.0
HKD2_k127_515979_2 ADP-glyceromanno-heptose 6-epimerase activity K00311 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.5.5.1 0.0000000000000000000000000000000000000000001723 172.0
HKD2_k127_515979_3 cheY-homologous receiver domain - - - 0.000000000000000000003568 98.0
HKD2_k127_5160230_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 310.0
HKD2_k127_5160230_1 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000002594 225.0
HKD2_k127_5160230_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000004267 218.0
HKD2_k127_5160230_3 PFAM 3-carboxy-cis,cis-muconate lactonizing enzyme K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000004783 182.0
HKD2_k127_5160230_4 asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000442 165.0
HKD2_k127_5160230_5 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.0000000000000000000009582 95.0
HKD2_k127_5162101_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 4.22e-306 953.0
HKD2_k127_5162101_1 Sodium:neurotransmitter symporter family - - - 8.44e-261 813.0
HKD2_k127_5162101_10 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000002008 190.0
HKD2_k127_5162101_2 Amino acid permease - - - 1.419e-210 670.0
HKD2_k127_5162101_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 3.085e-195 636.0
HKD2_k127_5162101_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 496.0
HKD2_k127_5162101_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 400.0
HKD2_k127_5162101_6 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 399.0
HKD2_k127_5162101_7 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 367.0
HKD2_k127_5162101_8 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000004222 262.0
HKD2_k127_5162101_9 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000002376 228.0
HKD2_k127_5201161_0 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 415.0
HKD2_k127_5201161_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000004184 128.0
HKD2_k127_5201161_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000007687 115.0
HKD2_k127_5201427_0 ftsk spoiiie K03466 - - 1.245e-218 704.0
HKD2_k127_5201427_1 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 510.0
HKD2_k127_5201427_10 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000007885 113.0
HKD2_k127_5201427_11 Helix-hairpin-helix motif K02237 - - 0.000000000000007354 83.0
HKD2_k127_5201427_2 heat shock protein binding K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 450.0
HKD2_k127_5201427_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 429.0
HKD2_k127_5201427_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 329.0
HKD2_k127_5201427_5 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.000000000000000000000000000000000000000000000000000000001608 211.0
HKD2_k127_5201427_6 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000002384 183.0
HKD2_k127_5201427_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K12733 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000002116 164.0
HKD2_k127_5201427_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K02652,K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000005091 147.0
HKD2_k127_5201427_9 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000003258 124.0
HKD2_k127_5230660_0 glutamate synthase alpha subunit K00265 - 1.4.1.13,1.4.1.14 0.0 1680.0
HKD2_k127_5235070_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 8.763e-268 835.0
HKD2_k127_5235070_1 Belongs to the TPP enzyme family K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 2.565e-223 721.0
HKD2_k127_5235070_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 587.0
HKD2_k127_5235070_3 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 414.0
HKD2_k127_5235070_4 Aconitase family (aconitate hydratase) K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000727 213.0
HKD2_k127_5235070_5 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000028 201.0
HKD2_k127_5256051_0 mismatched DNA binding K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 517.0
HKD2_k127_5256051_1 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 398.0
HKD2_k127_5256051_10 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000001193 203.0
HKD2_k127_5256051_11 RNA pseudouridylate synthase K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000002943 201.0
HKD2_k127_5256051_12 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000008917 202.0
HKD2_k127_5256051_13 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000002284 182.0
HKD2_k127_5256051_14 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000001084 184.0
HKD2_k127_5256051_15 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000001968 158.0
HKD2_k127_5256051_16 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000009895 156.0
HKD2_k127_5256051_17 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000007877 145.0
HKD2_k127_5256051_18 DinB superfamily K07552 - - 0.0000000000000000000000000000000005874 137.0
HKD2_k127_5256051_19 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000001549 110.0
HKD2_k127_5256051_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 396.0
HKD2_k127_5256051_21 - - - - 0.0000000000000001406 87.0
HKD2_k127_5256051_22 ABC-2 family transporter protein K01992 - - 0.00000000000005775 83.0
HKD2_k127_5256051_23 cellulose binding - - - 0.0000006545 63.0
HKD2_k127_5256051_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 385.0
HKD2_k127_5256051_4 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 381.0
HKD2_k127_5256051_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000617 356.0
HKD2_k127_5256051_6 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 334.0
HKD2_k127_5256051_7 - K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
HKD2_k127_5256051_8 transporter of a GTP-driven Fe(2 ) uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008839 260.0
HKD2_k127_5256051_9 HhH-GPD family K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005778 248.0
HKD2_k127_5264900_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 467.0
HKD2_k127_5264900_1 extracellular polysaccharide biosynthetic process K07011,K16554,K20998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 352.0
HKD2_k127_5264900_2 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005337 255.0
HKD2_k127_5264900_3 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005805 267.0
HKD2_k127_5264900_4 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003265 265.0
HKD2_k127_5264900_5 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000008464 256.0
HKD2_k127_5264900_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000008967 213.0
HKD2_k127_5264900_7 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000003619 201.0
HKD2_k127_5264900_8 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000001084 168.0
HKD2_k127_5264900_9 rhs-related protein - - - 0.000185 46.0
HKD2_k127_5271254_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001676 302.0
HKD2_k127_5271254_1 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002123 299.0
HKD2_k127_5273990_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1094.0
HKD2_k127_5273990_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 414.0
HKD2_k127_5273990_11 Cysteine-rich CPXCG - - - 0.000000001018 66.0
HKD2_k127_5273990_2 glutamyl-tRNA reductase activity K02407,K02492 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 391.0
HKD2_k127_5273990_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 303.0
HKD2_k127_5273990_4 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 290.0
HKD2_k127_5273990_5 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
HKD2_k127_5273990_6 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000001651 160.0
HKD2_k127_5273990_7 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000005218 144.0
HKD2_k127_5273990_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000002023 65.0
HKD2_k127_5283309_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 314.0
HKD2_k127_5283309_1 endo-1,4-beta-xylanase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007319 278.0
HKD2_k127_5283309_2 Glycosyl hydrolase family 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008006 256.0
HKD2_k127_5283309_3 PFAM glycoside hydrolase family 10 K01181 - 3.2.1.8 0.000000000001239 70.0
HKD2_k127_5287790_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0 1023.0
HKD2_k127_5287790_1 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 346.0
HKD2_k127_5287790_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 344.0
HKD2_k127_5287790_3 proline dehydrogenase activity K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 300.0
HKD2_k127_5287790_4 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002746 286.0
HKD2_k127_5287790_5 Nucleoside recognition K06373,K06374 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000331 264.0
HKD2_k127_5287790_6 Nucleoside recognition K06373,K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000000001847 236.0
HKD2_k127_5287790_7 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000001212 159.0
HKD2_k127_5287790_8 - - - - 0.0000000000000000000000001271 115.0
HKD2_k127_5287790_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000001672 91.0
HKD2_k127_5315980_0 GTPase activity K03596 - - 4.378e-298 923.0
HKD2_k127_5315980_1 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 542.0
HKD2_k127_5315980_10 haloacid dehalogenase-like hydrolase - - - 0.000000000000004205 86.0
HKD2_k127_5315980_2 porphobilinogen synthase activity K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 475.0
HKD2_k127_5315980_3 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 458.0
HKD2_k127_5315980_4 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 435.0
HKD2_k127_5315980_5 coproporphyrinogen oxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 340.0
HKD2_k127_5315980_6 FAD dependent oxidoreductase K00109,K00273,K15736 - 1.1.99.2,1.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 332.0
HKD2_k127_5315980_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000005593 259.0
HKD2_k127_5315980_8 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000908 180.0
HKD2_k127_5315980_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000003742 127.0
HKD2_k127_5321813_0 hydrolase activity, hydrolyzing O-glycosyl compounds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 354.0
HKD2_k127_5321813_1 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000001464 204.0
HKD2_k127_5321813_2 Membrane - - - 0.000000000000000000000000000000000000000000000000000006836 204.0
HKD2_k127_5321813_3 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000001665 74.0
HKD2_k127_5336345_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 304.0
HKD2_k127_5336345_1 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 305.0
HKD2_k127_5336345_2 PFAM Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000004077 89.0
HKD2_k127_5345103_0 membrane organization K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 338.0
HKD2_k127_5345103_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000007131 203.0
HKD2_k127_5345103_2 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000265 95.0
HKD2_k127_5378762_0 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 389.0
HKD2_k127_5378762_1 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 377.0
HKD2_k127_5378762_2 Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000000000000000000000000000000001347 186.0
HKD2_k127_5378762_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000441 94.0
HKD2_k127_5393493_0 Domain of unknown function (DUF4091) - - - 3.223e-205 653.0
HKD2_k127_5393493_1 Glycosyl hydrolases family 38 N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 587.0
HKD2_k127_5393493_2 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 426.0
HKD2_k127_5404051_0 DNA-directed DNA polymerase activity K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 4.262e-268 848.0
HKD2_k127_5421652_0 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 444.0
HKD2_k127_5421652_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 322.0
HKD2_k127_5421652_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 314.0
HKD2_k127_5421652_3 GGDEF domain K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002243 238.0
HKD2_k127_5421652_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000001852 179.0
HKD2_k127_5421652_5 cysteine-type peptidase activity K13694,K13695 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 3.4.17.13 0.00000000000000000000000000000002356 135.0
HKD2_k127_5421652_6 PBP superfamily domain K02040 - - 0.0000000000000000000000006736 106.0
HKD2_k127_5493780_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 357.0
HKD2_k127_5493780_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005932 322.0
HKD2_k127_5493780_2 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006761 250.0
HKD2_k127_5493780_3 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000003151 248.0
HKD2_k127_5493780_4 D-aminoacyl-tRNA deacylase activity K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000001135 176.0
HKD2_k127_5493780_5 Arabinose efflux permease family protein - - - 0.000000000000000000000000000000000000000000007474 179.0
HKD2_k127_551571_0 Alpha-L-fucosidase K01206 - 3.2.1.51 2.992e-239 762.0
HKD2_k127_551571_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 1.28e-232 745.0
HKD2_k127_551571_2 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 470.0
HKD2_k127_551571_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000913 290.0
HKD2_k127_551571_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005664 244.0
HKD2_k127_551571_5 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000004443 136.0
HKD2_k127_551571_6 Sialate O-acetylesterase K05970 - 3.1.1.53 0.0000000000000000002349 91.0
HKD2_k127_552040_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.658e-295 930.0
HKD2_k127_552040_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 3.787e-206 654.0
HKD2_k127_552040_10 glycosyl transferase family 2 - - - 0.000000000000000003878 89.0
HKD2_k127_552040_2 PFAM RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 487.0
HKD2_k127_552040_3 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 473.0
HKD2_k127_552040_4 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 397.0
HKD2_k127_552040_5 phytoene synthase K02291 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000001729 245.0
HKD2_k127_552040_6 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000004219 178.0
HKD2_k127_552040_7 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000103 158.0
HKD2_k127_552040_8 iron ion binding K15746 - 1.14.15.24 0.000000000000000000000000001468 117.0
HKD2_k127_552040_9 B12 binding domain - - - 0.000000000000000000000009878 112.0
HKD2_k127_5528833_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 539.0
HKD2_k127_5528833_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 535.0
HKD2_k127_5528833_10 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000000000000000000000008086 164.0
HKD2_k127_5528833_11 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000001073 139.0
HKD2_k127_5528833_12 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000009252 134.0
HKD2_k127_5528833_2 4 iron, 4 sulfur cluster binding K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
HKD2_k127_5528833_3 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 424.0
HKD2_k127_5528833_4 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 403.0
HKD2_k127_5528833_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 369.0
HKD2_k127_5528833_6 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000075 229.0
HKD2_k127_5528833_7 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000523 245.0
HKD2_k127_5528833_8 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000004282 231.0
HKD2_k127_5528833_9 thiamine-phosphate kinase activity K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000001512 179.0
HKD2_k127_5557577_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.214e-204 646.0
HKD2_k127_5557577_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 581.0
HKD2_k127_5557577_10 integral membrane protein - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000002491 55.0
HKD2_k127_5557577_2 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 484.0
HKD2_k127_5557577_3 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 465.0
HKD2_k127_5557577_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 437.0
HKD2_k127_5557577_5 formate dehydrogenase K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 334.0
HKD2_k127_5557577_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001373 248.0
HKD2_k127_5557577_7 Sigma-70, region 4 K03088 - - 0.000000000000000004589 93.0
HKD2_k127_5557577_8 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000008796 77.0
HKD2_k127_5576948_0 PFAM DegT DnrJ EryC1 StrS aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 401.0
HKD2_k127_5576948_1 transferase activity, transferring glycosyl groups K00721,K03820 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 323.0
HKD2_k127_5576948_2 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 321.0
HKD2_k127_5576948_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002436 254.0
HKD2_k127_5591864_0 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 518.0
HKD2_k127_5591864_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 360.0
HKD2_k127_5591864_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 340.0
HKD2_k127_5591864_3 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 317.0
HKD2_k127_5591864_5 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000004869 207.0
HKD2_k127_5591864_6 amine dehydrogenase activity K21449 - - 0.00000000000000000000000000000007937 131.0
HKD2_k127_559737_0 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 1.518e-261 832.0
HKD2_k127_559737_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 463.0
HKD2_k127_559737_2 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 387.0
HKD2_k127_559737_3 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 325.0
HKD2_k127_559737_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 300.0
HKD2_k127_559737_5 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000002891 183.0
HKD2_k127_559737_6 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000007573 149.0
HKD2_k127_559737_7 glyoxalase III activity - - - 0.0000000000000000000000000005989 120.0
HKD2_k127_559737_8 aminopeptidase activity - - - 0.00000000000000000000000001339 119.0
HKD2_k127_559737_9 response regulator K03413 - - 0.0000000000000004638 84.0
HKD2_k127_5651551_0 Glycosyl hydrolase family 9 K01179 - 3.2.1.4 1.445e-294 925.0
HKD2_k127_5651551_1 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 410.0
HKD2_k127_5651551_10 - - - - 0.000003354 55.0
HKD2_k127_5651551_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 317.0
HKD2_k127_5651551_3 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001005 297.0
HKD2_k127_5651551_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
HKD2_k127_5651551_5 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000004924 156.0
HKD2_k127_5651551_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000139 139.0
HKD2_k127_5651551_7 cellulose binding - - - 0.000000000000000000000000000001182 138.0
HKD2_k127_5651551_8 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000004102 122.0
HKD2_k127_5651551_9 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000002023 79.0
HKD2_k127_5688028_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 318.0
HKD2_k127_5688028_1 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000001083 181.0
HKD2_k127_5688028_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000009649 164.0
HKD2_k127_5688028_3 Polysaccharide biosynthesis protein K03328 - - 0.00001429 57.0
HKD2_k127_5712417_0 Belongs to the glycosyl hydrolase 3 family K05349 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0008422,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015926,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.21 5.319e-290 912.0
HKD2_k127_5712417_1 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 3.449e-256 810.0
HKD2_k127_5712417_2 PFAM Glycosyl Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 550.0
HKD2_k127_5712417_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
HKD2_k127_5712417_4 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007585 226.0
HKD2_k127_5731831_0 Glycoside hydrolase 97 K01187,K21574 - 3.2.1.20,3.2.1.3 1.822e-299 935.0
HKD2_k127_5731831_1 Glycoside hydrolase family 30 K01201 - 3.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 290.0
HKD2_k127_5731831_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000277 106.0
HKD2_k127_5848787_0 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 555.0
HKD2_k127_5848787_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000818 94.0
HKD2_k127_5860347_0 acyl-CoA dehydrogenase activity K06446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 570.0
HKD2_k127_5860347_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 530.0
HKD2_k127_5860347_2 enoyl-[acyl-carrier-protein] reductase (NADH) activity K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 340.0
HKD2_k127_5860347_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002176 267.0
HKD2_k127_5860347_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.00000000000000000000000000000000000000000000000000003476 197.0
HKD2_k127_5860347_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000001618 120.0
HKD2_k127_5860347_6 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01219 - 3.2.1.81 0.0000000000000000000005442 109.0
HKD2_k127_5902276_0 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 424.0
HKD2_k127_5902276_1 symporter activity - - - 0.0000000000000000000189 98.0
HKD2_k127_5929903_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 560.0
HKD2_k127_5929903_1 stress-responsive transcriptional regulator K03973 - - 0.0000000001108 69.0
HKD2_k127_5929903_2 - - - - 0.00003176 53.0
HKD2_k127_5930171_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.78e-289 921.0
HKD2_k127_5930171_1 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 341.0
HKD2_k127_5930171_2 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000001938 224.0
HKD2_k127_5930171_3 aconitate hydratase K01681 - 4.2.1.3 0.00000000000000000000000000000000000000001791 157.0
HKD2_k127_5930171_4 PFAM ATP-dependent Clp protease adaptor protein ClpS - - - 0.0000000000000000000001482 101.0
HKD2_k127_5936610_0 Domain of unknown function (DUF4340) - - - 0.000000000007512 76.0
HKD2_k127_5936610_1 - - - - 0.0001551 51.0
HKD2_k127_5946606_0 Stage II sporulation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 472.0
HKD2_k127_5946606_1 amino acid carrier protein K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 376.0
HKD2_k127_5946606_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 300.0
HKD2_k127_5946606_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000002973 248.0
HKD2_k127_5946606_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004801 237.0
HKD2_k127_5946606_5 Belongs to the GcvT family K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000006459 147.0
HKD2_k127_5946606_6 - - - - 0.000000000000000000000000000001687 132.0
HKD2_k127_6043361_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 513.0
HKD2_k127_6043361_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
HKD2_k127_6043361_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000004358 214.0
HKD2_k127_6043361_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000003095 179.0
HKD2_k127_6055582_1 TonB-dependent receptor - - - 2.74e-311 978.0
HKD2_k127_6055582_10 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 458.0
HKD2_k127_6055582_11 X-Pro dipeptidyl-peptidase (S15 family) K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 452.0
HKD2_k127_6055582_12 cellulose binding K00505 - 1.14.18.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 446.0
HKD2_k127_6055582_13 carbohydrate transport K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 419.0
HKD2_k127_6055582_14 Tat pathway signal sequence domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 388.0
HKD2_k127_6055582_15 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 354.0
HKD2_k127_6055582_16 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 373.0
HKD2_k127_6055582_17 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 345.0
HKD2_k127_6055582_18 LacI family K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 300.0
HKD2_k127_6055582_19 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002401 270.0
HKD2_k127_6055582_2 glucan 1,4-alpha-glucosidase activity K01178 - 3.2.1.3 6.477e-290 924.0
HKD2_k127_6055582_20 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000004262 253.0
HKD2_k127_6055582_21 transmembrane transport K02025,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
HKD2_k127_6055582_22 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000004989 203.0
HKD2_k127_6055582_23 response to oxidative stress K04063 - - 0.0000000000000000000000000001445 121.0
HKD2_k127_6055582_24 amine dehydrogenase activity - - - 0.000000000000004427 89.0
HKD2_k127_6055582_26 Rubrerythrin - - - 0.000607 47.0
HKD2_k127_6055582_3 Cellobiose phosphorylase K00702 - 2.4.1.20 2.104e-256 815.0
HKD2_k127_6055582_4 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 2.32e-222 695.0
HKD2_k127_6055582_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 608.0
HKD2_k127_6055582_6 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 576.0
HKD2_k127_6055582_7 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 578.0
HKD2_k127_6055582_8 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 511.0
HKD2_k127_6055582_9 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 477.0
HKD2_k127_6126659_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 400.0
HKD2_k127_6126659_1 PD-(D/E)XK nuclease superfamily K01144,K03406,K03582,K03657,K03658,K07464,K16898,K19465 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5,3.1.12.1,3.6.4.12 0.0000000000000000002198 101.0
HKD2_k127_6126659_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07708 - 2.7.13.3 0.000002731 53.0
HKD2_k127_6150860_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 468.0
HKD2_k127_6150860_1 Trehalase K03931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 408.0
HKD2_k127_6150860_2 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 349.0
HKD2_k127_6150860_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.00000000001293 78.0
HKD2_k127_6208907_0 nucleotide-excision repair K03701 - - 1.178e-308 973.0
HKD2_k127_6208907_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000004781 190.0
HKD2_k127_6322526_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.688e-200 632.0
HKD2_k127_6322526_1 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 353.0
HKD2_k127_6427500_0 Transcriptional accessory protein K06959 - - 8.12e-293 918.0
HKD2_k127_6427500_1 PIN domain K07175 - - 7.571e-205 647.0
HKD2_k127_6427500_10 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000004188 222.0
HKD2_k127_6427500_11 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000002594 229.0
HKD2_k127_6427500_12 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000001717 195.0
HKD2_k127_6427500_14 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000002094 167.0
HKD2_k127_6427500_15 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000002417 134.0
HKD2_k127_6427500_16 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000001199 97.0
HKD2_k127_6427500_17 helix_turn_helix, Lux Regulon - - - 0.0000000000000003718 87.0
HKD2_k127_6427500_18 Binds the poly(A) tail of mRNA K13126 GO:0000288,GO:0000289,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006397,GO:0006401,GO:0006402,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008143,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0019219,GO:0019222,GO:0019439,GO:0019538,GO:0031323,GO:0031329,GO:0034641,GO:0034645,GO:0034655,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060211,GO:0060255,GO:0061013,GO:0065007,GO:0070717,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1900151,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903311 - 0.000000001018 66.0
HKD2_k127_6427500_19 SnoaL-like domain - - - 0.00002358 49.0
HKD2_k127_6427500_2 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 541.0
HKD2_k127_6427500_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 419.0
HKD2_k127_6427500_4 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 420.0
HKD2_k127_6427500_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 344.0
HKD2_k127_6427500_6 TIGRFAM pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 346.0
HKD2_k127_6427500_7 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001353 265.0
HKD2_k127_6427500_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
HKD2_k127_6435822_0 urocanate hydratase activity K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 5.603e-278 863.0
HKD2_k127_6435822_1 TonB-dependent receptor K02014 - - 7.738e-248 791.0
HKD2_k127_6435822_10 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 339.0
HKD2_k127_6435822_11 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 339.0
HKD2_k127_6435822_12 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 349.0
HKD2_k127_6435822_13 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 324.0
HKD2_k127_6435822_14 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000004747 251.0
HKD2_k127_6435822_15 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
HKD2_k127_6435822_16 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
HKD2_k127_6435822_17 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
HKD2_k127_6435822_18 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000009722 219.0
HKD2_k127_6435822_19 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000007877 214.0
HKD2_k127_6435822_2 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 589.0
HKD2_k127_6435822_20 DinB family - - - 0.000000000000000000000000000000000000000000000000000001424 197.0
HKD2_k127_6435822_21 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000002806 190.0
HKD2_k127_6435822_22 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000115 165.0
HKD2_k127_6435822_23 SMART protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000002384 160.0
HKD2_k127_6435822_24 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000003155 151.0
HKD2_k127_6435822_25 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000000000000000000000000000000001046 141.0
HKD2_k127_6435822_26 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000003081 130.0
HKD2_k127_6435822_27 THIamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000000000000007361 119.0
HKD2_k127_6435822_28 diguanylate cyclase K21022 - 2.7.7.65 0.00000000000000000000000003179 124.0
HKD2_k127_6435822_29 thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000002193 109.0
HKD2_k127_6435822_3 deaminase activity K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 533.0
HKD2_k127_6435822_30 cAMP biosynthetic process - - - 0.00000000000001159 89.0
HKD2_k127_6435822_31 phosphohistidine phosphatase K08296 - - 0.000000000000261 83.0
HKD2_k127_6435822_32 PspC domain K03973 - - 0.000000000000979 77.0
HKD2_k127_6435822_33 - - - - 0.0000000000339 65.0
HKD2_k127_6435822_34 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000003702 67.0
HKD2_k127_6435822_4 phosphorelay signal transduction system K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 441.0
HKD2_k127_6435822_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
HKD2_k127_6435822_6 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 409.0
HKD2_k127_6435822_7 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 375.0
HKD2_k127_6435822_8 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 377.0
HKD2_k127_6435822_9 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 357.0
HKD2_k127_6465404_0 Carbohydrate kinase, FGGY family protein K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 599.0
HKD2_k127_6465404_1 GTP binding K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 504.0
HKD2_k127_6465404_2 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 441.0
HKD2_k127_6465404_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 299.0
HKD2_k127_6465404_4 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001681 246.0
HKD2_k127_6465404_5 - - - - 0.000000000000000000000000000000000000000000000000001283 198.0
HKD2_k127_6465404_6 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000007115 176.0
HKD2_k127_6470170_0 - - - - 1.458e-203 716.0
HKD2_k127_6470170_1 Insecticidal toxin complex - - - 7.928e-202 703.0
HKD2_k127_6470170_2 - - - - 0.000000000000000000000000000007689 136.0
HKD2_k127_6470170_3 RHS protein - - - 0.00000000000000007283 98.0
HKD2_k127_6470170_4 S-layer homology domain - - - 0.00000000001126 81.0
HKD2_k127_6479846_0 Oligoendopeptidase f - - - 1.722e-246 781.0
HKD2_k127_6479846_1 Amidohydrolase family K06015 - 3.5.1.81 5.934e-227 717.0
HKD2_k127_6479846_10 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001494 237.0
HKD2_k127_6479846_11 Acetyltransferase (GNAT) domain K02348 - - 0.000000000000000000000000000000000000000000001591 171.0
HKD2_k127_6479846_12 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000009763 172.0
HKD2_k127_6479846_13 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000006387 159.0
HKD2_k127_6479846_14 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000009126 165.0
HKD2_k127_6479846_15 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000006289 149.0
HKD2_k127_6479846_16 KR domain K07124 - - 0.000000000000000000000000000000000003819 149.0
HKD2_k127_6479846_17 PFAM Rhomboid family - - - 0.00000000000000000000000000000000003464 145.0
HKD2_k127_6479846_18 Transglycosylase associated protein - - - 0.000000000000000000000000000815 114.0
HKD2_k127_6479846_19 Domain of unknown function (DUF4203) - - - 0.00000000000000000007426 97.0
HKD2_k127_6479846_2 lactate metabolic process - - - 2.586e-204 652.0
HKD2_k127_6479846_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 580.0
HKD2_k127_6479846_4 PFAM Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 576.0
HKD2_k127_6479846_5 PFAM Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 422.0
HKD2_k127_6479846_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
HKD2_k127_6479846_7 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 316.0
HKD2_k127_6479846_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 307.0
HKD2_k127_6479846_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008939 246.0
HKD2_k127_6482844_0 permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 386.0
HKD2_k127_6482844_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 382.0
HKD2_k127_6482844_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 386.0
HKD2_k127_6482844_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 302.0
HKD2_k127_6482844_4 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000104 192.0
HKD2_k127_6496060_0 Glycosyltransferase family 36 K18675 - 2.4.1.280 0.0 1071.0
HKD2_k127_6496060_1 Cytochrome c554 and c-prime K04771 - 3.4.21.107 2.731e-213 680.0
HKD2_k127_6496060_10 N-Acetylmuramoyl-L-alanine amidase K01447,K17733 - 3.5.1.28 0.0000000000000000000000001275 125.0
HKD2_k127_6496060_11 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00005887 53.0
HKD2_k127_6496060_2 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 585.0
HKD2_k127_6496060_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 508.0
HKD2_k127_6496060_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 424.0
HKD2_k127_6496060_5 Glyco_18 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008419 274.0
HKD2_k127_6496060_6 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001378 250.0
HKD2_k127_6496060_7 amino acid activation for nonribosomal peptide biosynthetic process K01176,K01448,K17713,K20952 GO:0003674,GO:0005198,GO:0005199,GO:0005575,GO:0005623,GO:0008150,GO:0009273,GO:0009987,GO:0030115,GO:0030312,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 3.2.1.1,3.5.1.28 0.000000000000000000000000000000000000000000000000000007477 218.0
HKD2_k127_6496060_8 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000007721 157.0
HKD2_k127_6496060_9 calcium- and calmodulin-responsive adenylate cyclase activity K01179 - 3.2.1.4 0.00000000000000000000000009534 124.0
HKD2_k127_6510156_0 DNA topoisomerase II activity K02469 - 5.99.1.3 0.0 1165.0
HKD2_k127_6510156_1 DNA topoisomerase II activity K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 5.765e-285 894.0
HKD2_k127_6510156_10 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 447.0
HKD2_k127_6510156_11 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 445.0
HKD2_k127_6510156_12 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 382.0
HKD2_k127_6510156_13 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 383.0
HKD2_k127_6510156_14 peptidyl-prolyl cis-trans isomerase activity K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 372.0
HKD2_k127_6510156_15 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 359.0
HKD2_k127_6510156_16 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 340.0
HKD2_k127_6510156_17 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 331.0
HKD2_k127_6510156_18 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 332.0
HKD2_k127_6510156_19 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 310.0
HKD2_k127_6510156_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.2e-272 874.0
HKD2_k127_6510156_20 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 308.0
HKD2_k127_6510156_21 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003656 286.0
HKD2_k127_6510156_22 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001977 267.0
HKD2_k127_6510156_23 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
HKD2_k127_6510156_24 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000008919 172.0
HKD2_k127_6510156_25 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000003368 154.0
HKD2_k127_6510156_26 FR47-like protein - - - 0.0000000000000000000000000000002461 132.0
HKD2_k127_6510156_27 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000008694 110.0
HKD2_k127_6510156_28 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000001337 81.0
HKD2_k127_6510156_29 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000002684 73.0
HKD2_k127_6510156_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 4.148e-208 664.0
HKD2_k127_6510156_30 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000001493 80.0
HKD2_k127_6510156_31 PPIC-type PPIASE domain - - - 0.0000000000001548 81.0
HKD2_k127_6510156_33 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000001108 54.0
HKD2_k127_6510156_34 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00003055 53.0
HKD2_k127_6510156_4 UDP-N-acetylmuramate-L-alanine ligase activity K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 2.424e-200 642.0
HKD2_k127_6510156_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 514.0
HKD2_k127_6510156_6 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 483.0
HKD2_k127_6510156_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 477.0
HKD2_k127_6510156_8 membrane insertase activity K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 467.0
HKD2_k127_6510156_9 PFAM penicillin-binding protein transpeptidase K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 470.0
HKD2_k127_6519004_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 2.174e-241 775.0
HKD2_k127_6519004_1 protein secretion K09800 - - 0.0000000000000000000000000000001798 130.0
HKD2_k127_6519004_2 Belongs to the peptidase S8 family - - - 0.0001063 47.0
HKD2_k127_6520999_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 427.0
HKD2_k127_6539525_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 5e-324 1004.0
HKD2_k127_6539525_1 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000000000000000000000005633 209.0
HKD2_k127_6539525_2 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000000001847 179.0
HKD2_k127_6539525_3 Succinate dehydrogenase Fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000007664 122.0
HKD2_k127_6551389_0 Tricorn protease C1 domain K08676 - - 5.749e-211 697.0
HKD2_k127_6551389_1 nucleotide catabolic process K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 255.0
HKD2_k127_6579043_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 497.0
HKD2_k127_6579043_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 451.0
HKD2_k127_6579043_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000007775 210.0
HKD2_k127_6579043_3 COG494 NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair General function prediction only K01515 - 3.6.1.13 0.00000000000000000000000000000000006676 143.0
HKD2_k127_6593740_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003065 294.0
HKD2_k127_6593740_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000284 246.0
HKD2_k127_6593740_2 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000121 206.0
HKD2_k127_6593740_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000003649 203.0
HKD2_k127_6613565_0 Peptidase S46 - GO:0003674,GO:0003824,GO:0004177,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 404.0
HKD2_k127_6613565_1 phosphoserine phosphatase activity K07052,K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 391.0
HKD2_k127_6655236_0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain K01776,K02549,K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 4.2.1.113,5.1.1.20,5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 377.0
HKD2_k127_6655236_1 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 383.0
HKD2_k127_6655236_2 beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000002109 220.0
HKD2_k127_6703580_0 amine dehydrogenase activity - - - 5.582e-215 702.0
HKD2_k127_6703580_1 Protein of unknown function (DUF541) K09797 - - 0.00000000000000000000000000000000000000000000000000000000003426 213.0
HKD2_k127_6703580_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000001964 196.0
HKD2_k127_6703580_3 Protease prsW family - - - 0.000000000000000000000000000000001305 143.0
HKD2_k127_6703580_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000002978 132.0
HKD2_k127_6703580_5 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000008378 77.0
HKD2_k127_6703580_6 STAS domain - - - 0.000005329 52.0
HKD2_k127_6710729_0 metalloendopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 341.0
HKD2_k127_6710729_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004631 283.0
HKD2_k127_6710729_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000005493 134.0
HKD2_k127_6710729_3 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000008665 66.0
HKD2_k127_6712450_0 NAD(P)-binding Rossmann-like domain K06955 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 310.0
HKD2_k127_6712450_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004045 273.0
HKD2_k127_6712450_2 - - - - 0.0000000000000000000000000000000000001066 143.0
HKD2_k127_6715323_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 306.0
HKD2_k127_6715323_1 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002889 286.0
HKD2_k127_6715323_2 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000365 197.0
HKD2_k127_6715323_3 Domain of unknown function (DUF5117) - - - 0.0000000000000000000000000003133 120.0
HKD2_k127_6715323_4 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.00000000000000000000000004887 110.0
HKD2_k127_6715323_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000001089 100.0
HKD2_k127_6720812_0 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 5.858e-203 644.0
HKD2_k127_6720812_1 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 523.0
HKD2_k127_6720812_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 476.0
HKD2_k127_6720812_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 432.0
HKD2_k127_6720812_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 346.0
HKD2_k127_6720812_5 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004714 280.0
HKD2_k127_6720812_6 proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000002568 243.0
HKD2_k127_6720812_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000002103 166.0
HKD2_k127_681593_0 - - - - 0.0 1295.0
HKD2_k127_681593_1 TonB-dependent receptor - - - 0.0 1041.0
HKD2_k127_681593_10 protein secretion - - - 0.0000000000000000000000000000000002966 137.0
HKD2_k127_681593_11 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000004344 103.0
HKD2_k127_681593_2 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 400.0
HKD2_k127_681593_3 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 393.0
HKD2_k127_681593_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002133 250.0
HKD2_k127_681593_5 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000954 216.0
HKD2_k127_681593_6 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000009126 211.0
HKD2_k127_681593_7 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000164 190.0
HKD2_k127_681593_8 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000009177 169.0
HKD2_k127_681593_9 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000003327 170.0
HKD2_k127_682316_0 PFAM GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 515.0
HKD2_k127_682316_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000004459 186.0
HKD2_k127_6837026_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 507.0
HKD2_k127_6837026_1 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 501.0
HKD2_k127_6837026_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000002769 151.0
HKD2_k127_6837026_3 DNA-binding helix-turn-helix protein K01356 - 3.4.21.88 0.000000000000000000009833 100.0
HKD2_k127_6837026_4 TonB-dependent Receptor Plug Domain - - - 0.0000000001539 73.0
HKD2_k127_6851716_0 1-deoxy-D-xylulose-5-phosphate synthase activity K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 4.374e-271 848.0
HKD2_k127_6851716_1 Cytochrome C-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 557.0
HKD2_k127_6851716_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K03797 - 3.1.11.6,3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 361.0
HKD2_k127_6851716_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 259.0
HKD2_k127_6851716_4 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000000001808 221.0
HKD2_k127_6851716_5 Predicted membrane protein (DUF2231) - - - 0.00000000000005248 78.0
HKD2_k127_6851716_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000003174 72.0
HKD2_k127_6861643_0 ATP-dependent DNA helicase activity K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 386.0
HKD2_k127_6861643_1 Homocysteine S-methyltransferase - - - 0.000000000000000000000000000000000000000007811 160.0
HKD2_k127_6861643_2 glycogen phosphorylase activity K00688,K00691 - 2.4.1.1,2.4.1.8 0.00000000000000000000000000000003819 130.0
HKD2_k127_6876893_0 Amylo-alpha-1,6-glucosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 346.0
HKD2_k127_6876893_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000007576 240.0
HKD2_k127_6876893_2 Glycosyl hydrolase-like 10 - - - 0.00000000000000000002579 106.0
HKD2_k127_6877192_0 TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 487.0
HKD2_k127_6877192_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 474.0
HKD2_k127_6877192_11 FecR protein - - - 0.0000000000000000005285 98.0
HKD2_k127_6877192_12 - - - - 0.00000000000000003255 89.0
HKD2_k127_6877192_13 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000007993 53.0
HKD2_k127_6877192_2 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 323.0
HKD2_k127_6877192_3 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002021 269.0
HKD2_k127_6877192_5 TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000000000000000009002 224.0
HKD2_k127_6877192_6 Chaperone - - - 0.0000000000000000000000000000000000000000000000000001094 196.0
HKD2_k127_6877192_7 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000004663 168.0
HKD2_k127_6877192_9 Bacterial regulatory proteins, luxR family K03088 - - 0.00000000000000000000000004316 117.0
HKD2_k127_6915634_0 GTP-binding protein TypA K06207 - - 1.862e-217 700.0
HKD2_k127_6915634_1 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 413.0
HKD2_k127_6915634_2 HI0933 family K07007 - - 0.000000000000000000000000007014 115.0
HKD2_k127_6927589_0 response to heat K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1061.0
HKD2_k127_6927589_1 nucleotide-excision repair K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 477.0
HKD2_k127_6927589_2 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 369.0
HKD2_k127_6927589_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000009801 271.0
HKD2_k127_6927589_4 protein trimerization - - - 0.0000000007005 68.0
HKD2_k127_697867_0 Fumarase C C-terminus - - - 9.195e-241 752.0
HKD2_k127_697867_1 Phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 588.0
HKD2_k127_697867_2 anaerobic c4-dicarboxylate K07791,K07792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 404.0
HKD2_k127_697867_3 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 339.0
HKD2_k127_697867_4 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 332.0
HKD2_k127_697867_5 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000000000000000000000001176 180.0
HKD2_k127_697867_6 PFAM Ion transport 2 domain protein - - - 0.000000000000000000000000000000001599 142.0
HKD2_k127_697867_7 cellulose binding - - - 0.000000000000000000492 100.0
HKD2_k127_698107_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 7.458e-215 681.0
HKD2_k127_698107_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 443.0
HKD2_k127_698107_2 Pas domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006403 258.0
HKD2_k127_698107_3 beta-lactamase activity K07126,K13582 - - 0.00000000000000000000002198 113.0
HKD2_k127_6992929_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 390.0
HKD2_k127_6992929_1 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.000000000000000000000006339 106.0
HKD2_k127_6992929_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000005788 69.0
HKD2_k127_7010076_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 415.0
HKD2_k127_7010076_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007472 232.0
HKD2_k127_7010076_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000002913 196.0
HKD2_k127_7010076_3 ApbE family - - - 0.00000000000000000000000000000000000000000000000288 188.0
HKD2_k127_7010076_4 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000002956 161.0
HKD2_k127_7034082_0 Sigma-54 interaction domain K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 522.0
HKD2_k127_7034082_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 422.0
HKD2_k127_7034082_2 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 295.0
HKD2_k127_7086900_0 xyloglucan:xyloglucosyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 422.0
HKD2_k127_7086900_1 phospholipase Carboxylesterase - - - 0.00000000000000000000000000000000001411 142.0
HKD2_k127_7129232_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1015.0
HKD2_k127_7129232_1 CTP synthase activity K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.326e-235 739.0
HKD2_k127_7129232_10 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 426.0
HKD2_k127_7129232_11 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 345.0
HKD2_k127_7129232_12 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 302.0
HKD2_k127_7129232_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 314.0
HKD2_k127_7129232_14 dUTP biosynthetic process K01494,K01520 - 3.5.4.13,3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 285.0
HKD2_k127_7129232_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000003144 265.0
HKD2_k127_7129232_16 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000455 179.0
HKD2_k127_7129232_17 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000002735 169.0
HKD2_k127_7129232_18 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000425 167.0
HKD2_k127_7129232_19 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000001338 164.0
HKD2_k127_7129232_2 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.486e-235 738.0
HKD2_k127_7129232_20 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000107 161.0
HKD2_k127_7129232_21 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000001111 148.0
HKD2_k127_7129232_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000003087 116.0
HKD2_k127_7129232_23 regulation of translation K03530 - - 0.0000000000000000000000000003637 117.0
HKD2_k127_7129232_24 Helix-turn-helix domain - - - 0.000000000000001892 86.0
HKD2_k127_7129232_25 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000009218 78.0
HKD2_k127_7129232_3 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 612.0
HKD2_k127_7129232_4 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 613.0
HKD2_k127_7129232_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 522.0
HKD2_k127_7129232_6 PFAM aldo keto reductase K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 514.0
HKD2_k127_7129232_7 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 518.0
HKD2_k127_7129232_8 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 469.0
HKD2_k127_7129232_9 peptidase S16 K01338,K04076,K04770 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 448.0
HKD2_k127_7174657_0 Transferase K02527,K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 405.0
HKD2_k127_7174657_1 Glycosyl transferase, family 9 K02843 - - 0.0000000000000000000000000000000000000000000000000000000000005647 225.0
HKD2_k127_7174657_2 magnesium chelatase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000002183 162.0
HKD2_k127_7174657_3 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000001496 173.0
HKD2_k127_72312_0 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000009904 264.0
HKD2_k127_72312_1 ABC-2 type transporter K09690 - - 0.00000000000000000001154 97.0
HKD2_k127_72312_2 Lipocalin-like domain - - - 0.0000000000000000000153 93.0
HKD2_k127_7303492_0 protein refolding K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 6.813e-265 824.0
HKD2_k127_7303492_1 PFAM Alpha amylase, catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 490.0
HKD2_k127_7303492_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 342.0
HKD2_k127_7303492_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 323.0
HKD2_k127_7303492_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000009112 252.0
HKD2_k127_7303492_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000001804 154.0
HKD2_k127_7303492_6 transcriptional regulator K09017 - - 0.00000000000000000000000000008783 125.0
HKD2_k127_7303492_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.00000000001457 71.0
HKD2_k127_7316853_0 PFAM alpha amylase, catalytic region - - - 9.936e-205 657.0
HKD2_k127_7316853_1 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 453.0
HKD2_k127_7316853_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004004 245.0
HKD2_k127_7316853_11 Belongs to the 'phage' integrase family K03733 - - 0.000000000000000000000000000000000000000000000000000000000000002472 229.0
HKD2_k127_7316853_12 enterobactin catabolic process K07214 - - 0.000000000000000000000000000000000000000000000000000002402 210.0
HKD2_k127_7316853_13 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.000000000000000000000000000000000000000001288 169.0
HKD2_k127_7316853_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000004434 163.0
HKD2_k127_7316853_15 STAS domain K04749 - - 0.00000000000000000000000000000000000000188 151.0
HKD2_k127_7316853_16 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000000000000000000000002042 137.0
HKD2_k127_7316853_17 hemerythrin HHE cation binding domain - - - 0.0000000000002409 81.0
HKD2_k127_7316853_18 Tetratricopeptide repeat - - - 0.000000000005985 75.0
HKD2_k127_7316853_2 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 451.0
HKD2_k127_7316853_3 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 416.0
HKD2_k127_7316853_4 maltose binding K15770,K15771 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 397.0
HKD2_k127_7316853_5 Binding-protein-dependent transport system inner membrane component K02025,K15770,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 365.0
HKD2_k127_7316853_6 PFAM Stage II sporulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 362.0
HKD2_k127_7316853_7 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 327.0
HKD2_k127_7316853_8 Glycosyl transferase, family 9 K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 278.0
HKD2_k127_7316853_9 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000001007 230.0
HKD2_k127_7370055_0 belongs to the aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 3.823e-237 740.0
HKD2_k127_7370055_1 L-rhamnose isomerase activity K00848,K01813 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 404.0
HKD2_k127_7370055_10 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000005637 104.0
HKD2_k127_7370055_11 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K04032 - 2.5.1.17 0.0000000004128 67.0
HKD2_k127_7370055_2 propanediol catabolic process K15024 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 300.0
HKD2_k127_7370055_3 ethanolamine catabolic process K04027 - - 0.00000000000000000000000000000000000000003084 153.0
HKD2_k127_7370055_4 ethanolamine catabolic process K04027,K08696,K08700 - - 0.0000000000000000000000000000000000004355 141.0
HKD2_k127_7370055_5 DeoR C terminal sensor domain K22103 - - 0.000000000000000000000000000000000001595 148.0
HKD2_k127_7370055_6 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.0000000000000000000000000000000002448 137.0
HKD2_k127_7370055_7 ethanolamine catabolic process - - - 0.000000000000000000000000000000005545 130.0
HKD2_k127_7370055_8 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000000000000000008655 119.0
HKD2_k127_7370055_9 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000000001344 110.0
HKD2_k127_7409037_0 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005039 256.0
HKD2_k127_7409037_1 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.000000000000000000000000000000000000000000000000000006123 209.0
HKD2_k127_7466963_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 2.245e-258 805.0
HKD2_k127_7466963_1 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005084 279.0
HKD2_k127_7466963_2 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003468 246.0
HKD2_k127_7466963_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000002589 231.0
HKD2_k127_7500653_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006913 404.0
HKD2_k127_7500653_1 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 341.0
HKD2_k127_7500653_2 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001298 251.0
HKD2_k127_7500653_3 Ethyl tert-butyl ether degradation - - - 0.000000000000000000000000000001627 126.0
HKD2_k127_7561246_0 oligopeptide transport K03305 - - 7.837e-229 717.0
HKD2_k127_7561246_1 Protein of unknown function, DUF255 K06888 - - 4.221e-217 694.0
HKD2_k127_7561246_2 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 508.0
HKD2_k127_7561246_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 417.0
HKD2_k127_7561246_4 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000001473 196.0
HKD2_k127_7561246_5 Class I peptide chain release factor K15034 - - 0.000000000000000000000000000001396 126.0
HKD2_k127_7570637_0 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1047.0
HKD2_k127_7570637_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0000000000002022 72.0
HKD2_k127_7670007_0 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 306.0
HKD2_k127_7670007_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000001105 155.0
HKD2_k127_7670007_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 0.000000000000000000001134 99.0
HKD2_k127_7670007_3 lycopene cyclase - - - 0.0000000000000000000243 98.0
HKD2_k127_7670007_4 TIGRFAM lycopene cyclase domain - - - 0.0000000000000000001365 95.0
HKD2_k127_7735304_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1368.0
HKD2_k127_7735304_1 nodulation K00612 - - 8.135e-281 875.0
HKD2_k127_7735304_11 Belongs to the 5'-nucleotidase family - - - 0.000000000000000000004425 108.0
HKD2_k127_7735304_12 - - - - 0.0000000000000001973 80.0
HKD2_k127_7735304_13 - - - - 0.00000000000002437 79.0
HKD2_k127_7735304_2 succinyl-diaminopimelate desuccinylase activity K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 571.0
HKD2_k127_7735304_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 379.0
HKD2_k127_7735304_4 C-terminal AAA-associated domain K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 362.0
HKD2_k127_7735304_5 (ABC) transporter K02471,K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009237 281.0
HKD2_k127_7735304_6 PFAM FecR protein K01179,K03933 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004081 271.0
HKD2_k127_7735304_7 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000009551 205.0
HKD2_k127_7735304_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000002852 190.0
HKD2_k127_7735304_9 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000005628 122.0
HKD2_k127_7748637_0 PFAM glycoside hydrolase family 2 sugar binding - - - 2.226e-281 882.0
HKD2_k127_7748637_1 PFAM TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 336.0
HKD2_k127_7748637_2 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002624 276.0
HKD2_k127_7748637_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000003133 168.0
HKD2_k127_7748637_4 Belongs to the peptidase S8 family K06113,K12685 - 3.2.1.99 0.000000000000000000000000000000000004785 158.0
HKD2_k127_7748637_5 Belongs to the 5'-nucleotidase family - - - 0.000000000000000000000001095 115.0
HKD2_k127_7748899_0 Glycosyl hydrolases family 38 N-terminal domain - - - 9.832e-260 839.0
HKD2_k127_7748899_1 hydrolase, family 65, central catalytic - - - 9.446e-258 818.0
HKD2_k127_7748899_2 Alpha-L-fucosidase K01206 - 3.2.1.51 2.584e-211 664.0
HKD2_k127_7748899_3 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 581.0
HKD2_k127_7748899_4 Belongs to the glycosyl hydrolase 31 family K01811 - 3.2.1.177 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 459.0
HKD2_k127_7750383_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.253e-214 689.0
HKD2_k127_7750383_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.752e-205 649.0
HKD2_k127_7750383_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 451.0
HKD2_k127_7787158_0 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 3.95e-258 809.0
HKD2_k127_7787158_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 7.799e-221 697.0
HKD2_k127_7787158_2 Xylose isomerase domain protein TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 396.0
HKD2_k127_7787158_3 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 391.0
HKD2_k127_7787158_4 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 334.0
HKD2_k127_7787158_5 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000009764 149.0
HKD2_k127_7796623_0 Belongs to the glycosyl hydrolase 2 family K01190 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 0.0 1048.0
HKD2_k127_7796623_1 regulation of response to stimulus - - - 2.746e-219 717.0
HKD2_k127_7796623_10 Tfp pilus assembly protein FimV - - - 0.00000000000892 73.0
HKD2_k127_7796623_11 COGs COG1108 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.0000132 56.0
HKD2_k127_7796623_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 486.0
HKD2_k127_7796623_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 447.0
HKD2_k127_7796623_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 329.0
HKD2_k127_7796623_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000002937 228.0
HKD2_k127_7796623_6 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000001019 224.0
HKD2_k127_7796623_7 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000001824 217.0
HKD2_k127_7796623_8 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000001365 189.0
HKD2_k127_7796623_9 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000005556 117.0
HKD2_k127_7808841_0 single-stranded DNA 5'-3' exodeoxyribonuclease activity K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 579.0
HKD2_k127_7808841_1 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.0000000000000000000000000000000000938 138.0
HKD2_k127_7808841_2 - K07164,K22391 - 3.5.4.16 0.00000000000000000000000001703 112.0
HKD2_k127_7808841_3 - - - - 0.0001195 52.0
HKD2_k127_7828377_0 GHMP kinase K05305 - 2.7.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 476.0
HKD2_k127_7828377_1 PFAM inositol monophosphatase - - - 0.00000000001555 66.0
HKD2_k127_7830474_0 IMP dehydrogenase activity K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 4.847e-208 676.0
HKD2_k127_7830474_1 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 597.0
HKD2_k127_7830474_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 456.0
HKD2_k127_7830474_3 phosphorelay signal transduction system K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 452.0
HKD2_k127_7830474_4 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 354.0
HKD2_k127_7830474_5 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 331.0
HKD2_k127_7830474_6 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K07164,K22391 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 315.0
HKD2_k127_7830474_7 phosphorelay signal transduction system - - - 0.000000000000000000000000000485 118.0
HKD2_k127_7830474_8 Histidine kinase - - - 0.00000000000000001991 93.0
HKD2_k127_7830474_9 Zinc ribbon domain K07164 - - 0.000000000000005302 83.0
HKD2_k127_7857286_0 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 443.0
HKD2_k127_7857286_1 beta-galactosidase activity K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 295.0
HKD2_k127_7857286_2 PAP2 superfamily C-terminal - - - 0.000000000000000000000000000000000000000000000000003207 190.0
HKD2_k127_7857286_3 Methyltransferase - - - 0.000000000000000000000001111 121.0
HKD2_k127_7857286_4 Integral membrane protein TerC family - - - 0.0000000000000003844 78.0
HKD2_k127_7873579_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 543.0
HKD2_k127_7873579_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000001118 147.0
HKD2_k127_7873579_2 SNARE associated Golgi protein - - - 0.00000000000000000000000000000008819 133.0
HKD2_k127_7873579_4 membrane protein (DUF2078) K08982 - - 0.00000000000004535 79.0
HKD2_k127_7878377_0 6-phosphogluconolactonase activity - - - 3.592e-299 942.0
HKD2_k127_7878377_1 transferase activity, transferring glycosyl groups K00694,K00786 - 2.4.1.12 4.604e-220 693.0
HKD2_k127_7878377_10 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007552 419.0
HKD2_k127_7878377_11 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 395.0
HKD2_k127_7878377_12 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 388.0
HKD2_k127_7878377_13 phosphate acetyltransferase K00029,K00625,K13788 - 1.1.1.40,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 384.0
HKD2_k127_7878377_14 Sigma-54 interaction domain K03413,K13589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 379.0
HKD2_k127_7878377_15 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 353.0
HKD2_k127_7878377_16 glycogen (starch) synthase activity K00703,K00754 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 333.0
HKD2_k127_7878377_17 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 326.0
HKD2_k127_7878377_18 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 327.0
HKD2_k127_7878377_19 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 339.0
HKD2_k127_7878377_2 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 3.236e-197 635.0
HKD2_k127_7878377_20 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 332.0
HKD2_k127_7878377_21 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 291.0
HKD2_k127_7878377_22 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002447 285.0
HKD2_k127_7878377_23 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001102 279.0
HKD2_k127_7878377_24 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000181 284.0
HKD2_k127_7878377_25 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002632 295.0
HKD2_k127_7878377_26 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003819 299.0
HKD2_k127_7878377_27 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007067 274.0
HKD2_k127_7878377_28 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007131 261.0
HKD2_k127_7878377_29 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000003444 243.0
HKD2_k127_7878377_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 583.0
HKD2_k127_7878377_30 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002557 261.0
HKD2_k127_7878377_31 PFAM glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000001819 231.0
HKD2_k127_7878377_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000007899 236.0
HKD2_k127_7878377_33 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000003165 212.0
HKD2_k127_7878377_34 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000001383 217.0
HKD2_k127_7878377_35 PFAM Uncharacterised ACR, COG1259 K03617,K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0030312,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000001815 203.0
HKD2_k127_7878377_36 - K07283 - - 0.00000000000000000000000000000000000000000000000000000006032 206.0
HKD2_k127_7878377_37 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000001387 203.0
HKD2_k127_7878377_38 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.0000000000000000000000000000000000000000000000001186 178.0
HKD2_k127_7878377_39 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000009368 177.0
HKD2_k127_7878377_4 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 551.0
HKD2_k127_7878377_40 - - - - 0.000000000000000000000000000000000000000000000008401 177.0
HKD2_k127_7878377_41 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000002574 174.0
HKD2_k127_7878377_42 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000003868 173.0
HKD2_k127_7878377_43 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000007695 160.0
HKD2_k127_7878377_45 Putative zincin peptidase - - - 0.0000000000000000000000000000000000003793 148.0
HKD2_k127_7878377_46 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000009358 149.0
HKD2_k127_7878377_47 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000001182 151.0
HKD2_k127_7878377_48 Methionine biosynthesis protein MetW K02169 - 2.1.1.197 0.000000000000000000000000000000001789 139.0
HKD2_k127_7878377_49 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000003199 129.0
HKD2_k127_7878377_5 aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 514.0
HKD2_k127_7878377_50 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000001427 130.0
HKD2_k127_7878377_51 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000003305 133.0
HKD2_k127_7878377_52 Transcriptional regulator K21903 - - 0.0000000000000000000000000002829 117.0
HKD2_k127_7878377_53 Ribosomal prokaryotic L21 protein K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000001442 114.0
HKD2_k127_7878377_54 response regulator, receiver - - - 0.000000000000000000000000001525 130.0
HKD2_k127_7878377_55 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K04757 - 2.7.11.1 0.00000000000000000000000001377 115.0
HKD2_k127_7878377_56 peptidoglycan binding K03749,K07114,K08300,K09859 - 3.1.26.12 0.0000000000000000000009231 106.0
HKD2_k127_7878377_57 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000003433 98.0
HKD2_k127_7878377_58 - - - - 0.0000000000000000000213 92.0
HKD2_k127_7878377_59 Polysaccharide biosynthesis protein - - - 0.000000000000002374 89.0
HKD2_k127_7878377_6 PFAM beta-lactamase domain protein K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 495.0
HKD2_k127_7878377_60 - - - - 0.000000000000007574 79.0
HKD2_k127_7878377_61 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000001734 75.0
HKD2_k127_7878377_62 - - - - 0.0000007023 60.0
HKD2_k127_7878377_63 Tetratricopeptide repeat - - - 0.00001778 58.0
HKD2_k127_7878377_64 Releases the N-terminal proline from various substrates K01259 - 3.4.11.5 0.0000225 56.0
HKD2_k127_7878377_65 Binds directly to 16S ribosomal RNA K02968 - - 0.000108 48.0
HKD2_k127_7878377_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 434.0
HKD2_k127_7878377_8 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 430.0
HKD2_k127_7878377_9 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 428.0
HKD2_k127_7929273_0 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 584.0
HKD2_k127_7929273_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000008287 222.0
HKD2_k127_7929273_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000002321 143.0
HKD2_k127_7929273_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000002137 123.0
HKD2_k127_7942626_0 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 1.167e-198 631.0
HKD2_k127_7942626_1 Putative citrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 420.0
HKD2_k127_7942626_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 409.0
HKD2_k127_7942626_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0001724 51.0
HKD2_k127_7970895_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 425.0
HKD2_k127_7970895_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000004889 104.0
HKD2_k127_7970895_2 - - - - 0.0000000000000000004468 92.0
HKD2_k127_7970895_3 - - - - 0.0000003244 56.0
HKD2_k127_7970895_4 Psort location OuterMembrane, score - - - 0.00003883 50.0
HKD2_k127_7980822_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 3.678e-204 646.0
HKD2_k127_7980822_1 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 2.53e-198 625.0
HKD2_k127_7980822_10 regulation of microtubule-based process K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000002601 244.0
HKD2_k127_7980822_11 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HKD2_k127_7980822_12 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000006996 244.0
HKD2_k127_7980822_13 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
HKD2_k127_7980822_14 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000006152 221.0
HKD2_k127_7980822_15 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000003328 178.0
HKD2_k127_7980822_16 Protein of unknown function (DUF3109) - - - 0.0000000000000000000000000000000000000000001676 169.0
HKD2_k127_7980822_18 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000000000000000000000000005483 147.0
HKD2_k127_7980822_19 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000544 146.0
HKD2_k127_7980822_2 peptidase activity, acting on L-amino acid peptides K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 610.0
HKD2_k127_7980822_20 Oxidoreductase - - - 0.00000000000000000000000000000003939 138.0
HKD2_k127_7980822_21 - - - - 0.00000000000000187 91.0
HKD2_k127_7980822_22 Belongs to the UPF0403 family - - - 0.000000000000008515 75.0
HKD2_k127_7980822_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 496.0
HKD2_k127_7980822_4 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 473.0
HKD2_k127_7980822_5 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 443.0
HKD2_k127_7980822_6 DNA mediated transformation K02342,K03168,K03703,K04096 - 2.7.7.7,5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 344.0
HKD2_k127_7980822_7 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 289.0
HKD2_k127_7980822_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004456 297.0
HKD2_k127_7980822_9 Fe-S protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002981 260.0
HKD2_k127_8052770_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 395.0
HKD2_k127_8052770_1 CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000202 241.0
HKD2_k127_8052770_2 Transposase - - - 0.000000000000000000005684 95.0
HKD2_k127_8060202_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K05587 - 1.6.5.3 1.213e-220 704.0
HKD2_k127_8060202_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K05588 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 321.0
HKD2_k127_8060202_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002114 297.0
HKD2_k127_8060202_3 Coenzyme F420-reducing hydrogenase, alpha subunit K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001236 269.0
HKD2_k127_8060202_4 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000004127 248.0
HKD2_k127_8060202_5 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K05586 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000002103 214.0
HKD2_k127_8060202_6 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000004233 196.0
HKD2_k127_8060202_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000008997 94.0
HKD2_k127_8060202_8 Transcriptional regulator - - - 0.00006409 51.0
HKD2_k127_8101555_0 - - - - 1.333e-247 789.0
HKD2_k127_8101555_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 458.0
HKD2_k127_8101555_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 391.0
HKD2_k127_8101555_3 Periplasmic binding proteins and sugar binding domain of LacI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 329.0
HKD2_k127_8101555_4 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000001784 151.0
HKD2_k127_8101555_5 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.000000000000000000000003772 120.0
HKD2_k127_8105353_0 PFAM glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000004808 164.0
HKD2_k127_8105353_1 Carotenoid biosynthesis protein K22502 - 5.5.1.19 0.00000006433 64.0
HKD2_k127_8105353_2 - - - - 0.000006088 55.0
HKD2_k127_8110775_0 Bacterial periplasmic substrate-binding proteins K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 430.0
HKD2_k127_8110775_1 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 390.0
HKD2_k127_8110775_2 Phage integrase family K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 385.0
HKD2_k127_8110775_3 Binding-protein-dependent transport system inner membrane component K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
HKD2_k127_8110775_4 Binding-protein-dependent transport system inner membrane component K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 306.0
HKD2_k127_8110775_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000001053 172.0
HKD2_k127_8123621_0 carboxylase, biotin carboxylase K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 546.0
HKD2_k127_8123621_1 negative regulation of DNA recombination K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 529.0
HKD2_k127_8123621_2 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 421.0
HKD2_k127_8123621_3 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000006151 189.0
HKD2_k127_8123621_4 short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000005338 163.0
HKD2_k127_8123621_5 PFAM Yqey-like protein K09117 - - 0.00000000000000000000000000000000006673 139.0
HKD2_k127_8123621_6 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000003822 110.0
HKD2_k127_8123621_7 Biotin-requiring enzyme - - - 0.00000000000000000002749 96.0
HKD2_k127_8141753_0 Response regulator, receiver K01007 - 2.7.9.2 0.0 1382.0
HKD2_k127_8141753_1 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 1.367e-247 771.0
HKD2_k127_8141753_10 DNA recombination K03546,K03631 - - 0.000000000000000000000003292 117.0
HKD2_k127_8141753_11 response regulator K07782 - - 0.00000000000000000000009808 108.0
HKD2_k127_8141753_12 histidine kinase-, DNA gyrase B - - - 0.000000004906 64.0
HKD2_k127_8141753_13 Class III cytochrome C family - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000009353 48.0
HKD2_k127_8141753_2 Histidine kinase K02482 - 2.7.13.3 7.999e-224 709.0
HKD2_k127_8141753_3 phosphorelay signal transduction system K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 450.0
HKD2_k127_8141753_4 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 421.0
HKD2_k127_8141753_5 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 314.0
HKD2_k127_8141753_6 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000001445 243.0
HKD2_k127_8141753_7 - - - - 0.0000000000000000000000000000000001733 138.0
HKD2_k127_8141753_8 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000001882 134.0
HKD2_k127_8141753_9 - - - - 0.000000000000000000000000000000002715 135.0
HKD2_k127_8167304_0 xyloglucan:xyloglucosyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 364.0
HKD2_k127_8167304_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
HKD2_k127_8167304_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002795 248.0
HKD2_k127_82980_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.613e-210 677.0
HKD2_k127_82980_1 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 610.0
HKD2_k127_82980_2 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 606.0
HKD2_k127_82980_3 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 331.0
HKD2_k127_82980_4 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000002386 226.0
HKD2_k127_82980_5 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K01612,K03182,K16874 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 4.1.1.61,4.1.1.98 0.000000000000000000000000000000006119 138.0
HKD2_k127_8299446_0 membrane organization K07126,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 607.0
HKD2_k127_8299446_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 536.0
HKD2_k127_8299446_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 507.0
HKD2_k127_8299446_3 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 392.0
HKD2_k127_8300123_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 347.0
HKD2_k127_8300123_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005294 249.0
HKD2_k127_8300123_2 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000004759 182.0
HKD2_k127_8300123_3 cell adhesion involved in biofilm formation - - - 0.00002073 48.0
HKD2_k127_8315212_0 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 393.0
HKD2_k127_8315212_1 GHMP kinase K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 391.0
HKD2_k127_8315212_2 proline dipeptidase activity K18829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009349 284.0
HKD2_k127_8315212_3 Aldose 1-epimerase K01785 GO:0003674,GO:0003824,GO:0004034,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0006082,GO:0006790,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1902776,GO:1902777 5.1.3.3 0.00000000002128 65.0
HKD2_k127_8405323_0 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 473.0
HKD2_k127_8405323_1 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 434.0
HKD2_k127_8405323_2 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000002168 214.0
HKD2_k127_8405323_4 epimerase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000009422 78.0
HKD2_k127_8405323_5 Peptidase family M48 K03799 - - 0.00000000000006248 82.0
HKD2_k127_8409163_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 588.0
HKD2_k127_8409163_1 xyloglucan:xyloglucosyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 582.0
HKD2_k127_8409163_2 Domain of unknown function (DUF5127) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 335.0
HKD2_k127_8409163_3 hydrolase family 92 - - - 0.00000000000000000028 103.0
HKD2_k127_8409163_4 Carbohydrate esterase, sialic acid-specific acetylesterase K05970 - 3.1.1.53 0.000004217 51.0
HKD2_k127_8410182_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000002084 204.0
HKD2_k127_8410182_1 Protein of unknown function (DUF4013) - - - 0.000000000000000000000001953 111.0
HKD2_k127_8410182_2 Domain of unknown function (DUF1844) - - - 0.0000000000000001511 83.0
HKD2_k127_8410182_3 Cytochrome c - - - 0.0000000000003384 76.0
HKD2_k127_8410182_4 ABC transporter K18890 - - 0.000001771 49.0
HKD2_k127_8410182_5 -O-antigen K02847 - - 0.00003851 56.0
HKD2_k127_8418638_0 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 1.56e-218 684.0
HKD2_k127_8418638_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 569.0
HKD2_k127_8418638_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 479.0
HKD2_k127_8418638_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 384.0
HKD2_k127_8451601_0 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 531.0
HKD2_k127_8451601_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 490.0
HKD2_k127_8451601_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 443.0
HKD2_k127_8451601_3 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002867 256.0
HKD2_k127_8451601_4 DEAD DEAH box helicase K03724 - - 0.00000000000000000000000000000000000000000000000009313 198.0
HKD2_k127_8451601_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000004773 179.0
HKD2_k127_8451601_6 Methyltransferase domain protein - - - 0.0000000000000000000000000000000000186 145.0
HKD2_k127_8451601_7 - K21449 - - 0.00000000000000000000000000004531 126.0
HKD2_k127_8451601_8 amine dehydrogenase activity - - - 0.000000000000000000000000001931 124.0
HKD2_k127_8470648_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 466.0
HKD2_k127_8470648_1 protein secretion - - - 0.000000000000000000002699 108.0
HKD2_k127_8532451_0 - - - - 1.639e-224 715.0
HKD2_k127_8532451_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 550.0
HKD2_k127_8582095_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 330.0
HKD2_k127_8582095_1 LysM domain K08307,K12204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 313.0
HKD2_k127_8635815_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 594.0
HKD2_k127_8635815_1 membrane protein (DUF2339) - - - 0.0001663 53.0
HKD2_k127_8707880_0 Carbamoyl-phosphate synthetase large chain domain protein K01961 - 6.3.4.14,6.4.1.2 1.358e-207 655.0
HKD2_k127_8707880_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000002477 171.0
HKD2_k127_8707880_2 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000005256 138.0
HKD2_k127_8707880_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000002246 91.0
HKD2_k127_8849086_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 318.0
HKD2_k127_8849086_1 beta-lactamase activity K07126,K13582 - - 0.00000000000000000000000001519 117.0
HKD2_k127_8880905_0 protein targeting K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1301.0
HKD2_k127_8880905_1 N terminal of Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 471.0
HKD2_k127_8880905_10 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.00000000002525 68.0
HKD2_k127_8880905_11 toxin-antitoxin pair type II binding - - - 0.0007427 42.0
HKD2_k127_8880905_2 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 433.0
HKD2_k127_8880905_3 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 323.0
HKD2_k127_8880905_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595,K06883 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 309.0
HKD2_k127_8880905_5 spore germination K07790 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005666 248.0
HKD2_k127_8880905_6 FtsJ-like methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000001135 218.0
HKD2_k127_8880905_7 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000004466 177.0
HKD2_k127_8880905_8 Putative adhesin - - - 0.0000000000000000000000000000000000000000001361 171.0
HKD2_k127_8880905_9 glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683 - - - 0.00000000000000000000000000000002757 132.0
HKD2_k127_8918328_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 7.56e-232 736.0
HKD2_k127_8918328_1 elongation factor Tu domain 2 protein K06207 - - 0.000000000000000000000000000000000000007931 147.0
HKD2_k127_8925191_0 ABC transporter K17215 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 503.0
HKD2_k127_8925191_1 Branched-chain amino acid transport system / permease component K10439,K10440 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015591,GO:0015749,GO:0015750,GO:0015752,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0032991,GO:0034219,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 351.0
HKD2_k127_8925191_2 Periplasmic binding proteins and sugar binding domain of LacI family K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 301.0
HKD2_k127_8925191_3 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000005944 172.0
HKD2_k127_8925191_4 WD40-like Beta Propeller Repeat - - - 0.00000000000000006056 88.0
HKD2_k127_8943556_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404,K00405,K15862 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.0 1175.0
HKD2_k127_8943556_1 mercury ion transmembrane transporter activity K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 1.639e-230 738.0
HKD2_k127_8943556_10 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.000000000000000000000000000000000000183 146.0
HKD2_k127_8943556_11 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000000000000000000005267 137.0
HKD2_k127_8943556_12 FixH - - - 0.0000000000000001689 85.0
HKD2_k127_8943556_13 Cytochrome oxidase maturation protein - - - 0.00000000123 66.0
HKD2_k127_8943556_2 PFAM Fumarate lyase K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 579.0
HKD2_k127_8943556_3 4 iron, 4 sulfur cluster binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 567.0
HKD2_k127_8943556_4 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 410.0
HKD2_k127_8943556_5 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000005127 239.0
HKD2_k127_8943556_6 Cytochrome c K00406 - - 0.0000000000000000000000000000000000000000000000000000000005506 211.0
HKD2_k127_8943556_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000867 185.0
HKD2_k127_8943556_8 - - - - 0.00000000000000000000000000000000000000000000002305 189.0
HKD2_k127_8943556_9 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000002052 151.0
HKD2_k127_8963983_1 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 1.47e-250 801.0
HKD2_k127_8963983_10 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 360.0
HKD2_k127_8963983_11 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 354.0
HKD2_k127_8963983_12 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 359.0
HKD2_k127_8963983_13 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 351.0
HKD2_k127_8963983_14 transmembrane transport K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 291.0
HKD2_k127_8963983_15 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061 288.0
HKD2_k127_8963983_16 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000001726 260.0
HKD2_k127_8963983_17 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000205 252.0
HKD2_k127_8963983_18 Carbohydrate-binding family 9 - - - 0.00000000000000000000000000000000000000000000000000000000004549 213.0
HKD2_k127_8963983_19 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000001285 228.0
HKD2_k127_8963983_2 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 1.552e-244 778.0
HKD2_k127_8963983_20 B12 binding domain K18011 - 5.4.3.3 0.000000000000000000000000000000000000000000000000000000004851 210.0
HKD2_k127_8963983_21 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000003824 205.0
HKD2_k127_8963983_22 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001384 177.0
HKD2_k127_8963983_23 PFAM Stage II sporulation - - - 0.00000000000000000000000000000000000000000853 178.0
HKD2_k127_8963983_24 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000009825 149.0
HKD2_k127_8963983_25 regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000117 154.0
HKD2_k127_8963983_26 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.000000000000000000000000000000000002003 142.0
HKD2_k127_8963983_27 Putative, 10TM heavy-metal exporter K07089 - - 0.00000000000000000000000000000000001962 147.0
HKD2_k127_8963983_28 antisigma factor binding K04749 - - 0.0000000000000000000000000000000963 128.0
HKD2_k127_8963983_29 - - - - 0.0000000000000000000000000000002218 133.0
HKD2_k127_8963983_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 2.103e-223 701.0
HKD2_k127_8963983_30 polysaccharide catabolic process K01176,K01179 - 3.2.1.1,3.2.1.4 0.00000000000000000000002485 116.0
HKD2_k127_8963983_31 amine dehydrogenase activity - - - 0.00000000000000000000003213 115.0
HKD2_k127_8963983_32 protein secretion K15125 - - 0.0000000000000000000008481 113.0
HKD2_k127_8963983_33 - - - - 0.0000000000000000000187 97.0
HKD2_k127_8963983_34 Domain of unknown function (DUF4136) - - - 0.00000000000000000002951 100.0
HKD2_k127_8963983_35 - - - - 0.00000000000000003362 84.0
HKD2_k127_8963983_36 Outer membrane protein beta-barrel domain - - - 0.000000006416 65.0
HKD2_k127_8963983_37 Acetyltransferase (GNAT) domain - - - 0.00000005073 65.0
HKD2_k127_8963983_38 protein import K01179 - 3.2.1.4 0.00003354 53.0
HKD2_k127_8963983_4 Two component regulator propeller - - - 3.144e-217 712.0
HKD2_k127_8963983_5 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 569.0
HKD2_k127_8963983_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 488.0
HKD2_k127_8963983_7 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 491.0
HKD2_k127_8963983_8 metallopeptidase activity K01179,K09607 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 443.0
HKD2_k127_8963983_9 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 403.0
HKD2_k127_8976579_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 4.377e-252 786.0
HKD2_k127_8976579_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 552.0
HKD2_k127_8976579_10 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003512 128.0
HKD2_k127_8976579_11 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000001336 106.0
HKD2_k127_8976579_12 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000005913 97.0
HKD2_k127_8976579_13 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.000000000000000000002773 104.0
HKD2_k127_8976579_14 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000006758 93.0
HKD2_k127_8976579_15 Belongs to the UPF0109 family K06960 - - 0.000000000000001059 79.0
HKD2_k127_8976579_16 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000006422 61.0
HKD2_k127_8976579_17 - - - - 0.0001105 50.0
HKD2_k127_8976579_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 526.0
HKD2_k127_8976579_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 293.0
HKD2_k127_8976579_4 proton-transporting ATP synthase activity, rotational mechanism K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001504 283.0
HKD2_k127_8976579_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001765 282.0
HKD2_k127_8976579_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000002226 149.0
HKD2_k127_8976579_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000004305 139.0
HKD2_k127_8976579_8 heme binding K06194,K19304 - - 0.0000000000000000000000000000000006023 143.0
HKD2_k127_8976579_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000006105 137.0
HKD2_k127_8988957_0 Aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 540.0
HKD2_k127_8988957_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.000000000000000001114 89.0
HKD2_k127_8989471_0 tartrate metabolic process K01676,K01678 - 4.2.1.2 3.789e-237 744.0
HKD2_k127_8989471_1 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 2.869e-230 726.0
HKD2_k127_8989471_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 298.0
HKD2_k127_8989471_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001782 273.0
HKD2_k127_8989471_4 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.00000000000000000000000000000000000000000000000001267 184.0
HKD2_k127_8989471_5 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000005551 163.0
HKD2_k127_8989471_6 - - - - 0.000000000000000000000000000000000002797 148.0
HKD2_k127_8989471_7 Response regulator, receiver - - - 0.000000000006586 75.0
HKD2_k127_9015655_0 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 311.0
HKD2_k127_9015655_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000006876 230.0
HKD2_k127_9015655_2 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000005029 213.0
HKD2_k127_9015655_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000001429 194.0
HKD2_k127_9017944_0 Aminotransferase K21572 - - 0.0 1110.0
HKD2_k127_9017944_1 Site-specific recombinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 433.0
HKD2_k127_9017944_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 299.0
HKD2_k127_9017944_3 Protein of unknown function (DUF2846) - - - 0.0000000007488 69.0
HKD2_k127_9032144_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 369.0
HKD2_k127_9032144_1 Zinc metalloprotease (Elastase) K20274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 306.0
HKD2_k127_9032144_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000009533 64.0
HKD2_k127_9045173_0 aspartate-tRNA(Asn) ligase activity K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 7.357e-238 753.0
HKD2_k127_9045173_1 glutamine synthetase K01915 - 6.3.1.2 6.472e-227 711.0
HKD2_k127_9045173_10 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007293 257.0
HKD2_k127_9045173_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000006151 229.0
HKD2_k127_9045173_12 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000002617 213.0
HKD2_k127_9045173_13 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000003398 227.0
HKD2_k127_9045173_14 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000000000000000001268 209.0
HKD2_k127_9045173_15 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000001129 198.0
HKD2_k127_9045173_16 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000001183 182.0
HKD2_k127_9045173_17 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.0000000000000000000000000000000000000000000000007459 183.0
HKD2_k127_9045173_18 - - - - 0.00000000000000000000000000000000000000000001164 165.0
HKD2_k127_9045173_19 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000000002315 165.0
HKD2_k127_9045173_2 4-Hydroxyphenylpyruvate dioxygenase - - - 3.213e-197 629.0
HKD2_k127_9045173_20 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000166 108.0
HKD2_k127_9045173_21 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000000007866 111.0
HKD2_k127_9045173_22 Cytochrome C-type biogenesis protein K02198 - - 0.00000000000000003796 89.0
HKD2_k127_9045173_3 Insulinase (Peptidase family M16) K07263 - - 9.149e-196 620.0
HKD2_k127_9045173_4 translation release factor activity K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 464.0
HKD2_k127_9045173_5 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 430.0
HKD2_k127_9045173_6 lipoprotein localization to outer membrane K09808,K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 328.0
HKD2_k127_9045173_7 lipoprotein localization to outer membrane K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 302.0
HKD2_k127_9045173_8 cytochrome complex assembly K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001605 271.0
HKD2_k127_9045173_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000154 261.0
HKD2_k127_9048275_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 510.0
HKD2_k127_9048275_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 495.0
HKD2_k127_9048275_2 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 373.0
HKD2_k127_9048275_3 Amino acid permease K20265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 358.0
HKD2_k127_9048275_4 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000002027 219.0
HKD2_k127_9048275_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000005621 199.0
HKD2_k127_9084707_0 Trehalase K03931 - - 0.0 1039.0
HKD2_k127_9084707_1 Glycogen debranching enzyme K18206 - 3.2.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 431.0
HKD2_k127_9084707_2 long-chain fatty acid transporting porin activity - - - 0.00004127 47.0
HKD2_k127_9104289_0 lysine biosynthetic process via aminoadipic acid - - - 1.216e-268 847.0
HKD2_k127_9104289_1 Aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 2.665e-219 691.0
HKD2_k127_9104289_10 Belongs to the DapA family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 342.0
HKD2_k127_9104289_11 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 338.0
HKD2_k127_9104289_12 FCD - - - 0.0000000000000000000000000000000000000000000000003573 187.0
HKD2_k127_9104289_13 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000000000000001017 141.0
HKD2_k127_9104289_14 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000001681 147.0
HKD2_k127_9104289_15 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000007993 138.0
HKD2_k127_9104289_16 Transcriptional regulator - - - 0.000000000000000000000000000001973 125.0
HKD2_k127_9104289_2 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 1.018e-217 683.0
HKD2_k127_9104289_3 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 4.637e-198 626.0
HKD2_k127_9104289_4 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 520.0
HKD2_k127_9104289_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 464.0
HKD2_k127_9104289_6 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 455.0
HKD2_k127_9104289_7 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 433.0
HKD2_k127_9104289_8 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 387.0
HKD2_k127_9104289_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 415.0
HKD2_k127_9177666_0 phosphorelay signal transduction system K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 471.0
HKD2_k127_9177666_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 299.0
HKD2_k127_9177666_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007378 286.0
HKD2_k127_9199220_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.18e-295 918.0
HKD2_k127_9199220_1 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
HKD2_k127_9199220_10 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000085 93.0
HKD2_k127_9199220_2 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 289.0
HKD2_k127_9199220_3 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000699 278.0
HKD2_k127_9199220_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000003609 271.0
HKD2_k127_9199220_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K00939,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000009257 224.0
HKD2_k127_9199220_6 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000001184 226.0
HKD2_k127_9199220_7 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000005035 205.0
HKD2_k127_9199220_8 - - - - 0.0000000000000000000000000000000001643 135.0
HKD2_k127_9199220_9 Membrane - - - 0.0000000000000000001259 99.0
HKD2_k127_9207688_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 381.0
HKD2_k127_9207688_1 PFAM YicC domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009675 278.0
HKD2_k127_9207688_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005011 277.0
HKD2_k127_9207688_3 Guanylate kinase homologues. K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000002987 181.0
HKD2_k127_9207688_4 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.000000000000000000000000000000000002788 143.0
HKD2_k127_9209271_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000004729 215.0
HKD2_k127_9209271_1 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000006211 145.0
HKD2_k127_9209271_2 efflux transmembrane transporter activity - - - 0.0000000000008957 71.0
HKD2_k127_9209271_3 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000002506 64.0
HKD2_k127_9232589_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 435.0
HKD2_k127_9232589_1 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000007035 245.0
HKD2_k127_9232589_2 Pfam:DUF59 - - - 0.00000000000000000000000000001708 121.0
HKD2_k127_9232589_3 Seems to be required for the assembly of the photosystem I complex - - - 0.0005921 45.0
HKD2_k127_9276128_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 516.0
HKD2_k127_9276128_1 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 449.0
HKD2_k127_9276128_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 381.0
HKD2_k127_9276128_3 tigrfam pas - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 308.0
HKD2_k127_9276128_4 acetylesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003033 234.0
HKD2_k127_9276128_5 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000000000006379 201.0
HKD2_k127_9276128_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000001285 177.0
HKD2_k127_9276128_7 Domain of unknown function (DUF4412) - - - 0.0007286 51.0
HKD2_k127_9314283_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.644e-268 842.0
HKD2_k127_9314283_1 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 5.315e-267 835.0
HKD2_k127_9314283_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000147 70.0
HKD2_k127_9314283_11 Endonuclease I - - - 0.00000235 60.0
HKD2_k127_9314283_2 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 496.0
HKD2_k127_9314283_3 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 511.0
HKD2_k127_9314283_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 398.0
HKD2_k127_9314283_5 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000007613 210.0
HKD2_k127_9314283_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000006921 194.0
HKD2_k127_9314283_7 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000001891 212.0
HKD2_k127_9314283_8 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000007485 116.0
HKD2_k127_9368917_0 proton-transporting ATP synthase activity, rotational mechanism K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 3.384e-253 786.0
HKD2_k127_9368917_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 449.0
HKD2_k127_9368917_2 mannose-1-phosphate guanylyltransferase activity K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 404.0
HKD2_k127_9368917_3 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 311.0
HKD2_k127_9368917_4 carbon-oxygen lyase activity, acting on polysaccharides K18691 - - 0.00000000000000000000000000000000000000000657 164.0
HKD2_k127_9368917_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000002753 138.0
HKD2_k127_9368917_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000002279 113.0
HKD2_k127_9388949_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 2.275e-225 705.0
HKD2_k127_9388949_1 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 1.286e-209 660.0
HKD2_k127_9388949_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000002547 94.0
HKD2_k127_9388949_3 - - - - 0.00000000002101 74.0
HKD2_k127_9392854_0 (ABC) transporter K06147,K18890 - - 4.273e-244 768.0
HKD2_k127_9392854_1 (ABC) transporter K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 618.0
HKD2_k127_9392854_10 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002033 246.0
HKD2_k127_9392854_11 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000005081 226.0
HKD2_k127_9392854_12 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000009593 221.0
HKD2_k127_9392854_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000001658 156.0
HKD2_k127_9392854_14 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000002516 125.0
HKD2_k127_9392854_15 Tetratricopeptide repeat - - - 0.000000000000000002273 95.0
HKD2_k127_9392854_17 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00847,K00852,K18478 - 2.7.1.15,2.7.1.184,2.7.1.4 0.000000000008488 76.0
HKD2_k127_9392854_18 - - - - 0.00002436 52.0
HKD2_k127_9392854_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 487.0
HKD2_k127_9392854_3 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 441.0
HKD2_k127_9392854_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 415.0
HKD2_k127_9392854_5 Chase2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 386.0
HKD2_k127_9392854_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 368.0
HKD2_k127_9392854_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 312.0
HKD2_k127_9392854_8 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001826 280.0
HKD2_k127_9392854_9 Dihydrouridine synthase (Dus) K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000001823 243.0
HKD2_k127_9406994_0 membrane organization K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 589.0
HKD2_k127_9406994_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 421.0
HKD2_k127_9406994_2 pyrimidine-nucleoside phosphorylase K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 386.0
HKD2_k127_9406994_3 TIGRFAM N-terminal double-transmembrane domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 330.0
HKD2_k127_9406994_4 inositol monophosphate 1-phosphatase activity K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 295.0
HKD2_k127_9406994_5 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000004903 249.0
HKD2_k127_9406994_6 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 256.0
HKD2_k127_9406994_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000003005 225.0
HKD2_k127_9406994_8 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000001691 179.0
HKD2_k127_9406994_9 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000006615 178.0
HKD2_k127_9466248_0 Peptidase family M3 K01284,K01414 - 3.4.15.5,3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 529.0
HKD2_k127_9466248_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 331.0
HKD2_k127_9466248_2 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003881 292.0
HKD2_k127_9466248_3 Na H antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002811 283.0
HKD2_k127_9466248_4 Cytidine and deoxycytidylate deaminase zinc-binding region K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000002759 209.0
HKD2_k127_9466248_5 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000007403 177.0
HKD2_k127_9466248_6 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000001097 176.0
HKD2_k127_9466248_7 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000000000000000001633 142.0
HKD2_k127_9466248_8 cellulose binding - - - 0.00000000000000000132 101.0
HKD2_k127_9478842_0 TonB-dependent receptor - - - 7.693e-271 859.0
HKD2_k127_9478842_2 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 409.0
HKD2_k127_9478842_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 337.0
HKD2_k127_9478842_4 C4-dicarboxylate anaerobic carrier - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001892 273.0
HKD2_k127_9478842_5 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000009083 238.0
HKD2_k127_9478842_6 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000001451 208.0
HKD2_k127_9497947_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 3.055e-228 723.0
HKD2_k127_9497947_1 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 567.0
HKD2_k127_9497947_10 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000006886 101.0
HKD2_k127_9497947_11 NHL repeat - - - 0.000000000000000000001985 110.0
HKD2_k127_9497947_12 ketosteroid isomerase - - - 0.00000009963 63.0
HKD2_k127_9497947_2 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 480.0
HKD2_k127_9497947_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 477.0
HKD2_k127_9497947_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003403 268.0
HKD2_k127_9497947_5 rRNA processing K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000006205 225.0
HKD2_k127_9497947_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000006092 199.0
HKD2_k127_9497947_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000003234 180.0
HKD2_k127_9497947_8 2 iron, 2 sulfur cluster binding K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000006654 166.0
HKD2_k127_9497947_9 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.0000000000000000000004938 112.0
HKD2_k127_9630919_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001297 215.0
HKD2_k127_9630919_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.0000000000000000000000000000000000000000002706 174.0
HKD2_k127_9630919_2 Domain of unknown function (DUF4878) - - - 0.0000002116 58.0
HKD2_k127_9635537_0 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 595.0
HKD2_k127_9635537_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000005213 107.0
HKD2_k127_987884_0 (ABC) transporter K02021,K06147,K06148,K11085 - - 2.377e-201 638.0
HKD2_k127_9881724_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 4.451e-215 672.0
HKD2_k127_9881724_1 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 6.789e-195 634.0
HKD2_k127_9881724_10 Protein of unknown function (DUF2846) - - - 0.00000000000000002584 87.0
HKD2_k127_9881724_11 - - - - 0.00007083 53.0
HKD2_k127_9881724_2 peptide catabolic process K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 465.0
HKD2_k127_9881724_3 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003623 276.0
HKD2_k127_9881724_4 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004474 258.0
HKD2_k127_9881724_5 M6 family metalloprotease domain - - - 0.000000000000000000000000000000000000000000000000000000000007923 219.0
HKD2_k127_9881724_6 TPR repeat - - - 0.00000000000000000000000000000000000000002216 162.0
HKD2_k127_9881724_7 Fungalysin/Thermolysin Propeptide Motif K20274 - - 0.00000000000000000000000000000000002582 152.0
HKD2_k127_9881724_8 cellulase activity K01186,K01197,K05988,K11931,K21449 - 3.2.1.11,3.2.1.18,3.2.1.35 0.000000000000000000000002607 120.0
HKD2_k127_9881724_9 nucleotide catabolic process K05996 - 3.4.17.18 0.0000000000000000008783 99.0
HKD2_k127_9901310_0 Sigma-54 interaction domain K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 493.0
HKD2_k127_9901310_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 376.0
HKD2_k127_9901310_2 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000005785 230.0
HKD2_k127_9901310_3 Outer membrane transport energization protein ExbD - - - 0.0000000000000000000000000000000000008475 144.0
HKD2_k127_9901310_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000000000000428 143.0
HKD2_k127_9901310_5 PFAM Biopolymer transport protein ExbD TolR - - - 0.0000000000000000000000000000000009735 136.0
HKD2_k127_9901310_6 ABC-type phosphate transport system periplasmic K02040 - - 0.00000000000000000000000000000005748 138.0
HKD2_k127_9901310_7 TPR Domain containing protein K12600 - - 0.00000000000000000000000009696 124.0
HKD2_k127_9901310_8 antisigma factor binding K04749 - - 0.0000000000000003079 86.0
HKD2_k127_9968100_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 547.0
HKD2_k127_9968100_1 NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 448.0
HKD2_k127_9968100_2 domain, Protein - - - 0.0000000000000000000001808 105.0
HKD2_k127_9986000_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 305.0
HKD2_k127_9986000_1 Catalyzes the dephosphorylation of D,L-glyceraldehyde 3- phosphate in vitro K07025 - - 0.000000000000000000000000000002866 129.0
HKD2_k127_9986000_2 holo-[acyl-carrier-protein] synthase activity K00950,K00997,K01207,K01775,K06133,K06925,K18014 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.6.3,2.7.8.7,3.2.1.52,4.3.1.14,5.1.1.1 0.000000000000000000000000001908 118.0
HKD2_k127_9986000_3 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.0000000000000000003026 87.0
HKD2_k127_9991277_0 membrane organization K03641,K07277 - - 0.0 1052.0
HKD2_k127_9991277_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 570.0
HKD2_k127_9991277_10 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 299.0
HKD2_k127_9991277_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001698 295.0
HKD2_k127_9991277_12 lipoprotein YddW precursor K01189 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004233 295.0
HKD2_k127_9991277_13 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000001091 231.0
HKD2_k127_9991277_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000001564 226.0
HKD2_k127_9991277_15 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000003507 197.0
HKD2_k127_9991277_16 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000003236 177.0
HKD2_k127_9991277_17 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000006286 181.0
HKD2_k127_9991277_18 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000007731 169.0
HKD2_k127_9991277_19 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000002462 156.0
HKD2_k127_9991277_2 exoribonuclease II activity K12573,K12585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 576.0
HKD2_k127_9991277_20 STAS domain K04749 - - 0.000000000000000000000001192 107.0
HKD2_k127_9991277_21 lactate metabolic process - - - 0.00000000000000000000001221 113.0
HKD2_k127_9991277_22 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000002474 108.0
HKD2_k127_9991277_23 Domain of unknown function (DUF4905) - - - 0.000000000007044 76.0
HKD2_k127_9991277_24 PFAM Family of - - - 0.000000000008368 80.0
HKD2_k127_9991277_25 Domain of Unknown Function (DUF748) - - - 0.0000008587 64.0
HKD2_k127_9991277_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 557.0
HKD2_k127_9991277_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 532.0
HKD2_k127_9991277_5 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 454.0
HKD2_k127_9991277_6 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003472 436.0
HKD2_k127_9991277_7 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 329.0
HKD2_k127_9991277_8 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 326.0
HKD2_k127_9991277_9 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 295.0