logo

Overview

ID MAG01786
Name HKD2_bin.28
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhizobiales
Family Xanthobacteraceae
Genus Pseudolabrys
Species
Assembly information
Completeness (%) 75.05
Contamination (%) 2.94
GC content (%) 60.0
N50 (bp) 23,080
Genome size (bp) 2,872,106

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2899

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10040156_0 4Fe-4S binding domain - - - 1.306e-281 874.0
HKD2_k127_10040156_1 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 6.727e-248 781.0
HKD2_k127_10040156_2 WD domain, G-beta repeat K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 596.0
HKD2_k127_10040156_3 MoeA domain protein domain I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000007856 236.0
HKD2_k127_10040156_4 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000001036 51.0
HKD2_k127_10159270_0 Proteasome-type protease K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 408.0
HKD2_k127_10159270_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 368.0
HKD2_k127_10159270_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 339.0
HKD2_k127_10159270_3 Phosphoribosyl transferase domain K00769 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001094 276.0
HKD2_k127_10159270_4 ChrR Cupin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000002134 218.0
HKD2_k127_10159270_5 A circularly permuted ATPgrasp - - - 0.000000006939 58.0
HKD2_k127_102159_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 572.0
HKD2_k127_102159_1 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 409.0
HKD2_k127_102159_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 379.0
HKD2_k127_102159_3 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006842 240.0
HKD2_k127_1047078_0 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 2.196e-233 737.0
HKD2_k127_1047078_1 Transglycosylase SLT domain K00786,K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 544.0
HKD2_k127_1047078_2 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 492.0
HKD2_k127_1047078_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 482.0
HKD2_k127_1047078_4 COG2269 Truncated, possibly inactive, lysyl-tRNA synthetase (class II) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 461.0
HKD2_k127_1047078_5 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 363.0
HKD2_k127_1047078_6 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 370.0
HKD2_k127_1047078_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 294.0
HKD2_k127_1047078_8 Crp-like helix-turn-helix domain K13642 - - 0.000000000000000000000000000000000000000000000000000000000000001383 224.0
HKD2_k127_11508_0 ABC-2 family transporter protein K13926 - - 0.0 1107.0
HKD2_k127_11508_1 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 5.221e-218 681.0
HKD2_k127_11508_10 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 312.0
HKD2_k127_11508_11 Putative vitamin uptake transporter K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006494 254.0
HKD2_k127_11508_12 DUF218 domain - - - 0.00000000000000000000000000000000000000000298 161.0
HKD2_k127_11508_13 Diguanylate cyclase - - - 0.00000000000000000000000000000949 122.0
HKD2_k127_11508_14 Cupredoxin-like domain - - - 0.0000000000000000000000000005946 119.0
HKD2_k127_11508_15 transcriptional regulator, XRE family K07726 - - 0.0000000000000000000000002482 108.0
HKD2_k127_11508_16 transcriptional regulator, ArsR family - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000206 97.0
HKD2_k127_11508_17 Lysozyme inhibitor LprI - - - 0.000000000000000009698 90.0
HKD2_k127_11508_18 DUF218 domain - - - 0.00000000000001318 75.0
HKD2_k127_11508_19 Protein of unknown function (DUF3551) - - - 0.000009414 53.0
HKD2_k127_11508_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 576.0
HKD2_k127_11508_3 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 382.0
HKD2_k127_11508_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 377.0
HKD2_k127_11508_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 378.0
HKD2_k127_11508_6 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 346.0
HKD2_k127_11508_7 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 311.0
HKD2_k127_11508_8 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 308.0
HKD2_k127_11508_9 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 307.0
HKD2_k127_116057_0 Conserved carboxylase domain K01571 - 4.1.1.3 3.322e-216 680.0
HKD2_k127_116057_1 Biotin carboxylase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 562.0
HKD2_k127_116057_2 PFAM Prokaryotic protein of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 384.0
HKD2_k127_116057_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA - - - 0.0000000000000000000000000000000000000008114 156.0
HKD2_k127_121399_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 572.0
HKD2_k127_121399_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 407.0
HKD2_k127_121399_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003753 232.0
HKD2_k127_121399_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000006757 215.0
HKD2_k127_127637_0 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 355.0
HKD2_k127_127637_1 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 319.0
HKD2_k127_127637_2 Transporter, major facilitator family protein K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 296.0
HKD2_k127_127637_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000001863 225.0
HKD2_k127_127637_4 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000006808 175.0
HKD2_k127_127637_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000003835 82.0
HKD2_k127_1293579_0 Phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 535.0
HKD2_k127_1293579_1 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002178 256.0
HKD2_k127_1293579_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002834 259.0
HKD2_k127_1298853_0 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 609.0
HKD2_k127_1298853_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 564.0
HKD2_k127_1298853_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 454.0
HKD2_k127_1298853_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 440.0
HKD2_k127_1298853_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 362.0
HKD2_k127_1298853_5 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 331.0
HKD2_k127_1299786_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1331.0
HKD2_k127_1299786_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.813e-300 937.0
HKD2_k127_1299786_10 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000000007299 177.0
HKD2_k127_1299786_11 Bacterial SH3 domain - - - 0.000000753 58.0
HKD2_k127_1299786_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 493.0
HKD2_k127_1299786_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 389.0
HKD2_k127_1299786_4 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001683 277.0
HKD2_k127_1299786_5 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000002488 235.0
HKD2_k127_1299786_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000000000000000000000228 210.0
HKD2_k127_1299786_7 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000003996 194.0
HKD2_k127_1299786_8 AMP binding K06149 - - 0.0000000000000000000000000000000000000000000000000000694 190.0
HKD2_k127_1299786_9 Predicted permease - - - 0.00000000000000000000000000000000000000000000000001863 192.0
HKD2_k127_1321312_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 505.0
HKD2_k127_1321312_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 464.0
HKD2_k127_1321312_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007868 278.0
HKD2_k127_1337753_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1020.0
HKD2_k127_1337753_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.428e-255 798.0
HKD2_k127_1337753_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001464 286.0
HKD2_k127_1337753_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003561 267.0
HKD2_k127_1337753_12 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000213 261.0
HKD2_k127_1337753_13 Creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000001978 218.0
HKD2_k127_1337753_14 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000000000000000001244 143.0
HKD2_k127_1337753_15 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000004319 147.0
HKD2_k127_1337753_16 DNA repair - - - 0.0000000000000000000000001513 117.0
HKD2_k127_1337753_17 - - - - 0.000000000000000000001409 98.0
HKD2_k127_1337753_18 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000002199 95.0
HKD2_k127_1337753_19 Protein of unknown function (DUF2390) - - - 0.000000000000007458 81.0
HKD2_k127_1337753_2 Reductase C-terminal K05297 - 1.18.1.1 6.427e-254 790.0
HKD2_k127_1337753_3 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 428.0
HKD2_k127_1337753_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 385.0
HKD2_k127_1337753_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 385.0
HKD2_k127_1337753_6 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 368.0
HKD2_k127_1337753_7 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 360.0
HKD2_k127_1337753_8 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 308.0
HKD2_k127_1337753_9 COG1985 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 297.0
HKD2_k127_1346341_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.941e-265 823.0
HKD2_k127_1346341_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 332.0
HKD2_k127_1346341_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 326.0
HKD2_k127_1346341_3 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000004199 184.0
HKD2_k127_1346341_4 ATP-grasp domain K09181 - - 0.00000001691 59.0
HKD2_k127_1346663_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1890.0
HKD2_k127_1346663_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1112.0
HKD2_k127_1346663_10 Protein of unknown function (DUF3829) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 458.0
HKD2_k127_1346663_11 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 432.0
HKD2_k127_1346663_12 Catechol dioxygenase N terminus K03381 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006725,GO:0008150,GO:0008152,GO:0008199,GO:0009056,GO:0009712,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0018576,GO:0018958,GO:0019114,GO:0019336,GO:0019439,GO:0019614,GO:0019615,GO:0042952,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 1.13.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 425.0
HKD2_k127_1346663_13 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 424.0
HKD2_k127_1346663_14 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 421.0
HKD2_k127_1346663_15 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 418.0
HKD2_k127_1346663_16 Putative S-adenosyl-L-methionine-dependent methyltransferase K00574,K18164 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 408.0
HKD2_k127_1346663_17 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 394.0
HKD2_k127_1346663_18 Extensin-like protein C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 383.0
HKD2_k127_1346663_19 transcriptional regulator, winged helix family K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 356.0
HKD2_k127_1346663_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009380,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 6.287e-309 963.0
HKD2_k127_1346663_20 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 346.0
HKD2_k127_1346663_21 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 332.0
HKD2_k127_1346663_22 Domain of unknown function (DUF4403) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 322.0
HKD2_k127_1346663_23 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 312.0
HKD2_k127_1346663_24 Belongs to the RNase T2 family K01166,K01169 - 3.1.27.1,3.1.27.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 310.0
HKD2_k127_1346663_25 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 304.0
HKD2_k127_1346663_26 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 306.0
HKD2_k127_1346663_27 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 300.0
HKD2_k127_1346663_28 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 298.0
HKD2_k127_1346663_29 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 288.0
HKD2_k127_1346663_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07638 - 2.7.13.3 6.55e-234 737.0
HKD2_k127_1346663_30 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002082 282.0
HKD2_k127_1346663_31 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001476 270.0
HKD2_k127_1346663_32 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005847 256.0
HKD2_k127_1346663_33 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004196 249.0
HKD2_k127_1346663_34 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001354 250.0
HKD2_k127_1346663_35 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000002601 232.0
HKD2_k127_1346663_36 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004728 236.0
HKD2_k127_1346663_37 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
HKD2_k127_1346663_38 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000001326 240.0
HKD2_k127_1346663_39 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000001603 238.0
HKD2_k127_1346663_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 609.0
HKD2_k127_1346663_40 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000009831 211.0
HKD2_k127_1346663_41 PFAM Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000000000000000002793 190.0
HKD2_k127_1346663_42 - - - - 0.0000000000000000000000000000000000000000000000001086 182.0
HKD2_k127_1346663_43 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000002165 177.0
HKD2_k127_1346663_44 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000001011 172.0
HKD2_k127_1346663_45 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000005975 141.0
HKD2_k127_1346663_46 - - - - 0.0000000000000000000000000000000001236 143.0
HKD2_k127_1346663_47 Membrane fusogenic activity K09806 - - 0.000000000000000000000000000000002786 130.0
HKD2_k127_1346663_48 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000000000000005741 128.0
HKD2_k127_1346663_49 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.000000000000000000000000000000007261 131.0
HKD2_k127_1346663_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 536.0
HKD2_k127_1346663_50 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000000000000000001863 132.0
HKD2_k127_1346663_51 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000004885 113.0
HKD2_k127_1346663_52 Domain of unknown function (DUF4403) - - - 0.0000000000000000000000001984 113.0
HKD2_k127_1346663_53 - - - - 0.0000000000000000000000002291 113.0
HKD2_k127_1346663_54 - - - - 0.000000000000000000000001045 114.0
HKD2_k127_1346663_55 - - - - 0.0000000000000000000009762 97.0
HKD2_k127_1346663_56 Protein of unknown function (DUF1460) - - - 0.000000000000000006294 94.0
HKD2_k127_1346663_57 - - - - 0.000000000000641 69.0
HKD2_k127_1346663_58 Domain of unknown function (DUF4403) - - - 0.000000002553 63.0
HKD2_k127_1346663_59 Outer membrane protein beta-barrel domain K16079 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000008682 53.0
HKD2_k127_1346663_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 521.0
HKD2_k127_1346663_60 - - - - 0.00009641 49.0
HKD2_k127_1346663_61 Domain of unknown function (DUF4403) - - - 0.0005959 50.0
HKD2_k127_1346663_62 Protein of unknown function (DUF3072) - - - 0.0008684 44.0
HKD2_k127_1346663_7 arsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 479.0
HKD2_k127_1346663_8 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 476.0
HKD2_k127_1346663_9 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 461.0
HKD2_k127_135090_0 acyl-CoA dehydrogenase K00248,K00249,K20035 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 403.0
HKD2_k127_135090_1 Short-chain dehydrogenase reductase SDR K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 399.0
HKD2_k127_135090_2 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000008632 227.0
HKD2_k127_1357220_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 494.0
HKD2_k127_1357220_1 Penicillin-insensitive murein endopeptidase K07261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004074 259.0
HKD2_k127_1357220_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000504 174.0
HKD2_k127_136095_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 458.0
HKD2_k127_136095_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000002056 216.0
HKD2_k127_136095_2 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000002595 125.0
HKD2_k127_137261_0 E1 component K00164 - 1.2.4.2 0.0 1660.0
HKD2_k127_137261_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1418.0
HKD2_k127_137261_10 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 2.471e-208 657.0
HKD2_k127_137261_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 3.127e-194 618.0
HKD2_k127_137261_12 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 612.0
HKD2_k127_137261_13 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 612.0
HKD2_k127_137261_14 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 579.0
HKD2_k127_137261_15 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 556.0
HKD2_k127_137261_16 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 569.0
HKD2_k127_137261_17 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 556.0
HKD2_k127_137261_18 MiaB-like tRNA modifying enzyme K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 544.0
HKD2_k127_137261_19 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 537.0
HKD2_k127_137261_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1110.0
HKD2_k127_137261_20 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 511.0
HKD2_k127_137261_21 Mo-co oxidoreductase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 482.0
HKD2_k127_137261_22 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 449.0
HKD2_k127_137261_23 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 452.0
HKD2_k127_137261_24 HpcH/HpaI aldolase/citrate lyase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 434.0
HKD2_k127_137261_25 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 433.0
HKD2_k127_137261_26 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 417.0
HKD2_k127_137261_27 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 416.0
HKD2_k127_137261_28 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 383.0
HKD2_k127_137261_29 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 379.0
HKD2_k127_137261_3 FtsX-like permease family K02004 - - 0.0 1060.0
HKD2_k127_137261_30 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 375.0
HKD2_k127_137261_31 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 362.0
HKD2_k127_137261_32 ABC transporter K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 343.0
HKD2_k127_137261_33 Inhibitor of apoptosis-promoting Bax1 K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 347.0
HKD2_k127_137261_34 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 329.0
HKD2_k127_137261_35 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 327.0
HKD2_k127_137261_36 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 318.0
HKD2_k127_137261_37 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 308.0
HKD2_k127_137261_38 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
HKD2_k127_137261_39 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 279.0
HKD2_k127_137261_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.895e-295 912.0
HKD2_k127_137261_40 Pyridoxamine 5'-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002913 273.0
HKD2_k127_137261_41 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005278 271.0
HKD2_k127_137261_42 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001575 274.0
HKD2_k127_137261_43 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000002018 265.0
HKD2_k127_137261_44 Redoxin K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005648 259.0
HKD2_k127_137261_45 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000593 259.0
HKD2_k127_137261_46 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 260.0
HKD2_k127_137261_47 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000001067 253.0
HKD2_k127_137261_48 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004442 254.0
HKD2_k127_137261_49 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000271 260.0
HKD2_k127_137261_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.433e-276 855.0
HKD2_k127_137261_50 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000001451 234.0
HKD2_k127_137261_51 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000003229 235.0
HKD2_k127_137261_52 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000000004228 230.0
HKD2_k127_137261_53 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000009564 224.0
HKD2_k127_137261_54 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000000000000000000000000000000000000004076 215.0
HKD2_k127_137261_55 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000167 207.0
HKD2_k127_137261_56 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000006766 205.0
HKD2_k127_137261_57 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000002559 209.0
HKD2_k127_137261_58 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006734 201.0
HKD2_k127_137261_59 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001176 177.0
HKD2_k127_137261_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.75e-264 819.0
HKD2_k127_137261_60 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000001021 171.0
HKD2_k127_137261_61 Protein of unknown function (DUF2794) - - - 0.00000000000000000000000000000000000000000002571 166.0
HKD2_k127_137261_62 - - - - 0.000000000000000000000000000000000000000006593 164.0
HKD2_k127_137261_63 Oxidoreductase molybdopterin binding - - - 0.000000000000000000000000000000000000003445 146.0
HKD2_k127_137261_64 - - - - 0.00000000000000000000000000000000000001992 150.0
HKD2_k127_137261_65 SMART Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000005563 145.0
HKD2_k127_137261_66 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000001613 101.0
HKD2_k127_137261_67 Cytochrome c - - - 0.00000000000000000001009 98.0
HKD2_k127_137261_68 - - - - 0.0000000000007256 72.0
HKD2_k127_137261_69 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000000003419 66.0
HKD2_k127_137261_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.366e-239 749.0
HKD2_k127_137261_70 - - - - 0.000000001683 65.0
HKD2_k127_137261_71 - - - - 0.0000001793 57.0
HKD2_k127_137261_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 9.445e-233 727.0
HKD2_k127_137261_9 tail specific protease K03797 - 3.4.21.102 9.112e-229 715.0
HKD2_k127_1376853_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 8.277e-218 687.0
HKD2_k127_1376853_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 580.0
HKD2_k127_1376853_2 DedA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 303.0
HKD2_k127_1376853_3 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.0000000000000000000000000000000000000002843 153.0
HKD2_k127_1376853_4 - - - - 0.000000000000000000006852 99.0
HKD2_k127_1402738_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1075.0
HKD2_k127_1402738_1 Histidine kinase K07716,K11357 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 8.671e-207 660.0
HKD2_k127_1402738_10 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001421 293.0
HKD2_k127_1402738_11 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005284 271.0
HKD2_k127_1402738_12 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006634 274.0
HKD2_k127_1402738_13 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 265.0
HKD2_k127_1402738_14 Putative zinc- or iron-chelating domain K09160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000817 242.0
HKD2_k127_1402738_15 Caudovirus prohead serine protease K06904 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002016 243.0
HKD2_k127_1402738_16 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids - - - 0.000000000000000000000000000000000000000000000000000000000000000000001045 242.0
HKD2_k127_1402738_17 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000002509 219.0
HKD2_k127_1402738_18 Flavodoxin-like fold K19784 - - 0.000000000000000000000000000000000000000000000000000000000005732 213.0
HKD2_k127_1402738_19 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000000000000000000000000000008397 205.0
HKD2_k127_1402738_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.216e-200 644.0
HKD2_k127_1402738_20 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000004573 191.0
HKD2_k127_1402738_21 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000002757 178.0
HKD2_k127_1402738_22 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000003014 180.0
HKD2_k127_1402738_23 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000000000000000000000002856 166.0
HKD2_k127_1402738_24 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000002488 156.0
HKD2_k127_1402738_25 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000007324 149.0
HKD2_k127_1402738_26 Domain of unknown function (DUF4142) K08995 - - 0.0000000000000000000000000000000002475 138.0
HKD2_k127_1402738_27 rhamnose metabolic process - - - 0.00000000000000000000000000000004141 129.0
HKD2_k127_1402738_28 Protein of unknown function (DUF992) - - - 0.000000000000000000000000003002 118.0
HKD2_k127_1402738_29 acetyl-CoA hydrolase K18288 - - 0.000000000000000000000000004047 117.0
HKD2_k127_1402738_3 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 511.0
HKD2_k127_1402738_30 - - - - 0.00000000000000000000000004569 119.0
HKD2_k127_1402738_31 - - - - 0.0000000000000000000009582 95.0
HKD2_k127_1402738_32 - - - - 0.000000000000000000002146 97.0
HKD2_k127_1402738_33 Family of unknown function (DUF5330) - - - 0.0000000000000000000107 97.0
HKD2_k127_1402738_34 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000001967 92.0
HKD2_k127_1402738_35 Tetratricopeptide repeats - - - 0.000000000000000006154 89.0
HKD2_k127_1402738_36 oxidoreductase - - - 0.0000000000000000721 82.0
HKD2_k127_1402738_37 membrane - - - 0.0000000000000008995 89.0
HKD2_k127_1402738_38 Phage portal protein - - - 0.000000000000001054 84.0
HKD2_k127_1402738_39 repeat-containing protein - - - 0.000000000000001388 79.0
HKD2_k127_1402738_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 489.0
HKD2_k127_1402738_40 Flp/Fap pilin component K02651 - - 0.0000000001567 65.0
HKD2_k127_1402738_41 repeat-containing protein - - - 0.000000001403 64.0
HKD2_k127_1402738_43 - - - - 0.00000415 51.0
HKD2_k127_1402738_44 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000009263 48.0
HKD2_k127_1402738_45 - - - - 0.00005272 48.0
HKD2_k127_1402738_46 PFAM Acetyl-CoA hydrolase transferase - - - 0.0001846 54.0
HKD2_k127_1402738_47 - - - - 0.0003157 46.0
HKD2_k127_1402738_48 Methyltransferase - - - 0.0004775 50.0
HKD2_k127_1402738_49 Calcineurin-like phosphoesterase K06953 - - 0.000686 44.0
HKD2_k127_1402738_5 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 452.0
HKD2_k127_1402738_50 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 0.00073 44.0
HKD2_k127_1402738_6 Phage portal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 414.0
HKD2_k127_1402738_7 acetyl-CoA hydrolase K18288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 396.0
HKD2_k127_1402738_8 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 359.0
HKD2_k127_1402738_9 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 298.0
HKD2_k127_1411126_0 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 581.0
HKD2_k127_1411126_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 424.0
HKD2_k127_1440326_0 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 1.626e-274 858.0
HKD2_k127_1440326_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 6.811e-274 850.0
HKD2_k127_1440326_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.523e-230 719.0
HKD2_k127_1440326_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 1.477e-227 712.0
HKD2_k127_1440326_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 2.292e-211 662.0
HKD2_k127_1440326_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 381.0
HKD2_k127_1440326_6 Sigma-70 factor, region 1.2 K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 362.0
HKD2_k127_1440326_7 Outer membrane protein beta-barrel domain - - - 0.0000000000000000001592 94.0
HKD2_k127_1440326_8 Opacity family porin protein - - - 0.000182 49.0
HKD2_k127_1445569_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.821e-300 929.0
HKD2_k127_1445569_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 437.0
HKD2_k127_1445569_10 - - - - 0.0001267 49.0
HKD2_k127_1445569_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 319.0
HKD2_k127_1445569_3 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004028 258.0
HKD2_k127_1445569_4 Haemolysin-III related K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000004965 250.0
HKD2_k127_1445569_5 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000000000000000000000000001736 162.0
HKD2_k127_1445569_6 - - - - 0.0000000000000001533 84.0
HKD2_k127_1445569_7 - - - - 0.0000000000001174 74.0
HKD2_k127_1445569_8 HdeA/HdeB family K19778 - - 0.000000007657 64.0
HKD2_k127_1445569_9 - - - - 0.0000002376 61.0
HKD2_k127_1499996_0 Hydrolase CocE NonD family K06978 - - 5.241e-255 798.0
HKD2_k127_1499996_1 Hydrolase CocE NonD family K06978 - - 2.458e-240 755.0
HKD2_k127_1499996_10 - - - - 0.00000008262 57.0
HKD2_k127_1499996_2 Acetamidase formamidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 469.0
HKD2_k127_1499996_3 Belongs to the ABC transporter superfamily K10111,K10112,K10191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 334.0
HKD2_k127_1499996_4 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 288.0
HKD2_k127_1499996_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000002264 217.0
HKD2_k127_1499996_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000001231 196.0
HKD2_k127_1499996_7 trehalose maltose binding protein K02027 - - 0.00000000000000000000000000000000001265 153.0
HKD2_k127_1499996_8 Phage integrase family - - - 0.00000000002847 69.0
HKD2_k127_1499996_9 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000009872 66.0
HKD2_k127_1523819_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0 1039.0
HKD2_k127_1523819_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 6.678e-276 861.0
HKD2_k127_1523819_2 branched-chain amino acid K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 300.0
HKD2_k127_1527808_0 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 378.0
HKD2_k127_1527808_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 376.0
HKD2_k127_1527808_2 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000009922 236.0
HKD2_k127_1531654_0 PHP domain K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1696.0
HKD2_k127_1531654_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 558.0
HKD2_k127_1531654_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K00406 - - 0.00000000000000000000001263 104.0
HKD2_k127_1531654_11 - - - - 0.00000000000000001043 89.0
HKD2_k127_1531654_12 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000001246 85.0
HKD2_k127_1531654_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 467.0
HKD2_k127_1531654_3 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 460.0
HKD2_k127_1531654_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 363.0
HKD2_k127_1531654_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 319.0
HKD2_k127_1531654_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 287.0
HKD2_k127_1531654_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000461 255.0
HKD2_k127_1531654_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000008533 202.0
HKD2_k127_1531654_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000005879 157.0
HKD2_k127_158022_0 TIGRFAM cytochrome c oxidase, cbb3-type, subunit I K00404 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 4.512e-320 984.0
HKD2_k127_158022_1 TIGRFAM cytochrome c oxidase accessory protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 7.083e-224 703.0
HKD2_k127_158022_10 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000000000004404 167.0
HKD2_k127_158022_11 FixH - - - 0.000000000000000000000000000000000001235 145.0
HKD2_k127_158022_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000001398 86.0
HKD2_k127_158022_13 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0000000000000005579 79.0
HKD2_k127_158022_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 517.0
HKD2_k127_158022_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 432.0
HKD2_k127_158022_4 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 415.0
HKD2_k127_158022_5 histidine kinase A domain protein K14986 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 407.0
HKD2_k127_158022_6 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002517 278.0
HKD2_k127_158022_7 Crp Fnr family K01420,K15861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002083 252.0
HKD2_k127_158022_8 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000000003066 204.0
HKD2_k127_158022_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 0.000000000000000000000000000000000000000000000000000000158 198.0
HKD2_k127_1581574_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.159e-232 729.0
HKD2_k127_1581574_1 rRNA binding K02968 - - 0.00000000000000000002179 91.0
HKD2_k127_158955_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.503e-251 783.0
HKD2_k127_160612_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 4.562e-305 946.0
HKD2_k127_160612_1 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 380.0
HKD2_k127_1654603_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 0.0 1161.0
HKD2_k127_1654603_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1149.0
HKD2_k127_1654603_10 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 444.0
HKD2_k127_1654603_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 444.0
HKD2_k127_1654603_12 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 430.0
HKD2_k127_1654603_13 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 430.0
HKD2_k127_1654603_14 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 431.0
HKD2_k127_1654603_15 enoyl-CoA hydratase K01692,K05605 - 3.1.2.4,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 405.0
HKD2_k127_1654603_16 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 385.0
HKD2_k127_1654603_17 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 370.0
HKD2_k127_1654603_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 362.0
HKD2_k127_1654603_19 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 348.0
HKD2_k127_1654603_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.122e-255 807.0
HKD2_k127_1654603_20 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00101,K15054 - 1.1.2.3,1.1.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 356.0
HKD2_k127_1654603_21 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 352.0
HKD2_k127_1654603_22 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 325.0
HKD2_k127_1654603_23 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 323.0
HKD2_k127_1654603_24 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 302.0
HKD2_k127_1654603_25 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 291.0
HKD2_k127_1654603_26 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002147 272.0
HKD2_k127_1654603_27 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001229 268.0
HKD2_k127_1654603_28 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006934 250.0
HKD2_k127_1654603_29 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002794 245.0
HKD2_k127_1654603_3 Sodium/hydrogen exchanger family - - - 3.169e-234 746.0
HKD2_k127_1654603_30 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000007656 238.0
HKD2_k127_1654603_31 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000004533 230.0
HKD2_k127_1654603_32 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000001611 212.0
HKD2_k127_1654603_33 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000009178 194.0
HKD2_k127_1654603_34 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000009704 193.0
HKD2_k127_1654603_35 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000003322 183.0
HKD2_k127_1654603_36 - - - - 0.000000000000000000000000000000000000000004854 158.0
HKD2_k127_1654603_37 Methyltransferase FkbM domain - - - 0.000000000004174 72.0
HKD2_k127_1654603_38 Methyltransferase FkbM domain - - - 0.0000005363 57.0
HKD2_k127_1654603_39 - - - - 0.0002039 48.0
HKD2_k127_1654603_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.973e-233 732.0
HKD2_k127_1654603_5 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.311e-202 633.0
HKD2_k127_1654603_6 Natural resistance-associated macrophage protein K03322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 603.0
HKD2_k127_1654603_7 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 597.0
HKD2_k127_1654603_8 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 571.0
HKD2_k127_1654603_9 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 475.0
HKD2_k127_1688172_0 Beta-ketoacyl synthase, C-terminal domain K00647 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.41 4.351e-227 708.0
HKD2_k127_1688172_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 563.0
HKD2_k127_1688172_2 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 326.0
HKD2_k127_1688172_3 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000000000000000000000004717 235.0
HKD2_k127_1688172_4 Bacterial SH3 domain K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
HKD2_k127_1688172_5 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000001917 223.0
HKD2_k127_1710981_0 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 421.0
HKD2_k127_1710981_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 332.0
HKD2_k127_1710981_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 305.0
HKD2_k127_1710981_3 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000002419 220.0
HKD2_k127_1710981_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000001057 217.0
HKD2_k127_1710981_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000005413 194.0
HKD2_k127_1710981_6 Domain of unknown function (DUF4399) - - - 0.00000000000000000000000000000000000000000002998 164.0
HKD2_k127_1710981_7 Protein of unknown function (DUF992) - - - 0.000000000000000000000000000000000000001324 155.0
HKD2_k127_1756786_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 515.0
HKD2_k127_1757976_0 Mo-co oxidoreductase dimerisation domain K17225 - - 2.495e-225 704.0
HKD2_k127_1757976_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000447 66.0
HKD2_k127_1782650_0 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 460.0
HKD2_k127_1782650_1 arsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 317.0
HKD2_k127_1782650_2 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.00000000000000006739 81.0
HKD2_k127_1876175_0 Histidine kinase - - - 4.089e-199 629.0
HKD2_k127_1876175_1 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 340.0
HKD2_k127_1876175_2 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000002713 197.0
HKD2_k127_1918406_0 Amidohydrolase family K01466 - 3.5.2.5 3.069e-234 733.0
HKD2_k127_1918406_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate K01703 - 4.2.1.33,4.2.1.35 8.173e-228 713.0
HKD2_k127_1918406_10 ATPases associated with a variety of cellular activities K01996,K11958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 313.0
HKD2_k127_1918406_11 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001958 269.0
HKD2_k127_1918406_12 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000002065 223.0
HKD2_k127_1918406_13 AntiSigma factor - - - 0.000000000000000000000000000000000000000000000000226 183.0
HKD2_k127_1918406_14 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000001711 139.0
HKD2_k127_1918406_15 Integrase core domain - - - 0.00000000000000000000000000000000008275 138.0
HKD2_k127_1918406_16 Cytochrome c, class I - - - 0.00000000000000000008979 93.0
HKD2_k127_1918406_17 Belongs to the 'phage' integrase family - - - 0.0000003196 57.0
HKD2_k127_1918406_18 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000007783 52.0
HKD2_k127_1918406_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 546.0
HKD2_k127_1918406_3 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 533.0
HKD2_k127_1918406_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 393.0
HKD2_k127_1918406_5 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 401.0
HKD2_k127_1918406_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 391.0
HKD2_k127_1918406_7 Isocitrate lyase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 374.0
HKD2_k127_1918406_8 oxidoreductase FAD NAD(P)-binding domain protein K18069,K21324,K21607 - 1.1.1.404 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 368.0
HKD2_k127_1918406_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
HKD2_k127_191965_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 609.0
HKD2_k127_191965_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 566.0
HKD2_k127_191965_2 Peptidase M16 inactive domain K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 496.0
HKD2_k127_191965_3 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000000000000000000000003083 193.0
HKD2_k127_191965_4 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000001517 122.0
HKD2_k127_1965598_0 Protein of unknown function (DUF459) K09795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 351.0
HKD2_k127_1965598_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 322.0
HKD2_k127_1965598_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000000000001775 192.0
HKD2_k127_1965598_3 Usg-like family - - - 0.000000000000000000000000000000000000000004019 156.0
HKD2_k127_1965598_4 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000000001106 134.0
HKD2_k127_216107_0 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 541.0
HKD2_k127_216107_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 325.0
HKD2_k127_2225334_0 Thiamine pyrophosphate enzyme, central domain K01577 - 4.1.1.8 0.0 1043.0
HKD2_k127_2225334_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 2.792e-289 897.0
HKD2_k127_2225334_10 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 313.0
HKD2_k127_2225334_11 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001564 289.0
HKD2_k127_2225334_12 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003287 269.0
HKD2_k127_2225334_13 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000000002911 195.0
HKD2_k127_2225334_14 Belongs to the GMC oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000001128 195.0
HKD2_k127_2225334_15 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000004294 177.0
HKD2_k127_2225334_2 Tripartite tricarboxylate transporter TctA family K07793 - - 4.498e-273 845.0
HKD2_k127_2225334_3 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit - - - 1.79e-256 801.0
HKD2_k127_2225334_4 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 4.528e-236 740.0
HKD2_k127_2225334_5 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 6.594e-233 728.0
HKD2_k127_2225334_6 GMC oxidoreductase - - - 6.637e-205 642.0
HKD2_k127_2225334_7 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 536.0
HKD2_k127_2225334_8 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 517.0
HKD2_k127_2225334_9 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 445.0
HKD2_k127_231869_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 294.0
HKD2_k127_231869_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000001927 212.0
HKD2_k127_231869_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K01860,K19802 - 5.1.1.20,5.5.1.1,5.5.1.7 0.000000000000000000000000000000000000000001743 168.0
HKD2_k127_2359053_0 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 494.0
HKD2_k127_2359053_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 392.0
HKD2_k127_2359053_2 SOS response K14160 - - 0.00000000000000000000000000000000000000006014 162.0
HKD2_k127_2431719_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 511.0
HKD2_k127_2431719_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 410.0
HKD2_k127_2431719_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000002373 158.0
HKD2_k127_2431719_3 Belongs to the GcvT family K00605 - 2.1.2.10 0.0000008746 52.0
HKD2_k127_250870_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1142.0
HKD2_k127_250870_1 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.000000000000255 71.0
HKD2_k127_2558544_0 Molybdopterin binding aldehyde oxidase and xanthine dehydrogenase K16877 - 1.3.99.8 2.177e-302 949.0
HKD2_k127_2558544_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 474.0
HKD2_k127_2558544_2 Protein of unknown function (DUF2848) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 301.0
HKD2_k127_2558544_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 297.0
HKD2_k127_2558544_4 PFAM molybdopterin dehydrogenase FAD-binding K03519,K16878 - 1.2.5.3,1.3.99.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 294.0
HKD2_k127_2558544_5 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000184 250.0
HKD2_k127_2558544_6 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005757 226.0
HKD2_k127_2558544_7 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000008412 230.0
HKD2_k127_2558544_8 [2Fe-2S] binding domain K16879 - 1.3.99.8 0.0000000000000000000000000000000000000000000000000000000212 202.0
HKD2_k127_2564883_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0 3162.0
HKD2_k127_2564883_1 MMPL family K07003 - - 3.692e-316 985.0
HKD2_k127_2564883_10 phytoene synthase K21678 - 2.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
HKD2_k127_2564883_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.00000000000000000000000000000000000000000000000003642 186.0
HKD2_k127_2564883_12 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000000000000000000000000001867 185.0
HKD2_k127_2564883_13 LTXXQ motif family protein - - - 0.0000000000000000003536 100.0
HKD2_k127_2564883_14 - - - - 0.000000001953 63.0
HKD2_k127_2564883_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.639e-315 977.0
HKD2_k127_2564883_3 Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 9.438e-312 978.0
HKD2_k127_2564883_4 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 3.687e-306 949.0
HKD2_k127_2564883_5 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 2.765e-203 636.0
HKD2_k127_2564883_6 Histidine kinase - - - 1.739e-196 630.0
HKD2_k127_2564883_7 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 501.0
HKD2_k127_2564883_8 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 488.0
HKD2_k127_2564883_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 455.0
HKD2_k127_2597140_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 407.0
HKD2_k127_2597140_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 404.0
HKD2_k127_2597140_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 386.0
HKD2_k127_2597140_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 338.0
HKD2_k127_2597140_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000009255 220.0
HKD2_k127_2597140_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000003781 172.0
HKD2_k127_2597140_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.00000000000000000000000000000008672 129.0
HKD2_k127_2597140_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.00000000000000000006869 92.0
HKD2_k127_2597438_0 Protein of unknown function (DUF561) K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 475.0
HKD2_k127_2597438_1 luciferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 377.0
HKD2_k127_2597438_2 Glutathione S-transferase, C-terminal domain K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 355.0
HKD2_k127_2597438_3 Bacterial PH domain - - - 0.000000000000000000000000000000000000002504 153.0
HKD2_k127_2602021_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.571e-281 876.0
HKD2_k127_2602021_1 MMPL family K03296 - - 4.749e-238 745.0
HKD2_k127_2602021_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.000000000000000000000000000002777 124.0
HKD2_k127_2602021_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.00000000000000000009428 91.0
HKD2_k127_2602021_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 516.0
HKD2_k127_2602021_3 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 456.0
HKD2_k127_2602021_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 410.0
HKD2_k127_2602021_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 364.0
HKD2_k127_2602021_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 334.0
HKD2_k127_2602021_7 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000001584 216.0
HKD2_k127_2602021_8 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000001419 188.0
HKD2_k127_2602021_9 Belongs to the HesB IscA family K13628,K15724 - - 0.0000000000000000000000000000000000000000000000008286 176.0
HKD2_k127_2645931_0 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1430.0
HKD2_k127_2645931_1 Ftsk_gamma K03466 - - 0.0 1049.0
HKD2_k127_2645931_10 Pantothenic acid kinase K00867 GO:0003674,GO:0003824,GO:0004594,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 520.0
HKD2_k127_2645931_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005468 518.0
HKD2_k127_2645931_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 500.0
HKD2_k127_2645931_13 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 478.0
HKD2_k127_2645931_14 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 459.0
HKD2_k127_2645931_15 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 438.0
HKD2_k127_2645931_16 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 413.0
HKD2_k127_2645931_17 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 407.0
HKD2_k127_2645931_18 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 410.0
HKD2_k127_2645931_19 Acetyltransferase (GNAT) domain K22310 - 2.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 399.0
HKD2_k127_2645931_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.563e-308 954.0
HKD2_k127_2645931_20 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 397.0
HKD2_k127_2645931_21 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
HKD2_k127_2645931_22 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 371.0
HKD2_k127_2645931_23 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 340.0
HKD2_k127_2645931_24 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 334.0
HKD2_k127_2645931_25 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 338.0
HKD2_k127_2645931_26 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 322.0
HKD2_k127_2645931_27 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 313.0
HKD2_k127_2645931_28 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 316.0
HKD2_k127_2645931_29 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 301.0
HKD2_k127_2645931_3 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 1.376e-294 917.0
HKD2_k127_2645931_30 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 292.0
HKD2_k127_2645931_31 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000007062 262.0
HKD2_k127_2645931_32 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000007367 252.0
HKD2_k127_2645931_33 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005313 246.0
HKD2_k127_2645931_34 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000201 240.0
HKD2_k127_2645931_35 cytochrome C peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000477 231.0
HKD2_k127_2645931_36 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008645 230.0
HKD2_k127_2645931_37 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000903 221.0
HKD2_k127_2645931_38 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000001099 218.0
HKD2_k127_2645931_39 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000003327 214.0
HKD2_k127_2645931_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.16e-253 782.0
HKD2_k127_2645931_40 electron transfer activity - - - 0.000000000000000000000000000000000000000000000000000000000004299 214.0
HKD2_k127_2645931_41 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000000008857 211.0
HKD2_k127_2645931_42 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000003608 209.0
HKD2_k127_2645931_43 Lipopolysaccharide-assembly K03643 - - 0.00000000000000000000000000000000000000000000000000000000004414 211.0
HKD2_k127_2645931_44 Smr domain - - - 0.00000000000000000000000000000000000000000000000000004911 194.0
HKD2_k127_2645931_45 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000827 189.0
HKD2_k127_2645931_46 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000001954 181.0
HKD2_k127_2645931_47 Protein of unknown function (DUF2628) - - - 0.0000000000000000000000000000000000000004614 154.0
HKD2_k127_2645931_48 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000007202 135.0
HKD2_k127_2645931_49 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000834 130.0
HKD2_k127_2645931_5 Binding-protein-dependent transport systems inner membrane component K02050 - - 1.382e-246 773.0
HKD2_k127_2645931_50 - - - - 0.0000000000000000000000357 107.0
HKD2_k127_2645931_51 Lytic transglycolase K03642 - - 0.0000000000000000000006961 96.0
HKD2_k127_2645931_52 Serine aminopeptidase, S33 - - - 0.0000000000000000000007711 105.0
HKD2_k127_2645931_53 Uncharacterized protein conserved in bacteria (DUF2171) - - - 0.0000000000000000002646 91.0
HKD2_k127_2645931_54 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000006827 94.0
HKD2_k127_2645931_55 histidine kinase A domain protein - - - 0.000000000000000000831 90.0
HKD2_k127_2645931_56 Response regulator receiver protein - - - 0.0000000000000005566 83.0
HKD2_k127_2645931_57 Protein of unknown function (DUF3309) - - - 0.00000000000004268 77.0
HKD2_k127_2645931_58 Lytic transglycolase K03642 - - 0.00000000000007695 79.0
HKD2_k127_2645931_59 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.00000001919 66.0
HKD2_k127_2645931_6 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.797e-237 737.0
HKD2_k127_2645931_7 PFAM Rh family protein ammonium transporter K03320 - - 1.011e-209 661.0
HKD2_k127_2645931_8 ABC transporter K02049 - - 1.283e-196 622.0
HKD2_k127_2645931_9 Aminotransferase class I and II K14261,K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 567.0
HKD2_k127_264616_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 595.0
HKD2_k127_264616_1 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 576.0
HKD2_k127_264616_2 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 368.0
HKD2_k127_264616_3 Dehydrogenase - - - 0.000000000000000000000000000000000000000001095 158.0
HKD2_k127_264616_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000005864 59.0
HKD2_k127_2677907_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 439.0
HKD2_k127_2677907_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000066 287.0
HKD2_k127_2677907_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000001339 92.0
HKD2_k127_2695082_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 428.0
HKD2_k127_2695082_1 Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 418.0
HKD2_k127_2695082_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 365.0
HKD2_k127_2695082_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000192 90.0
HKD2_k127_2711798_0 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 572.0
HKD2_k127_2711798_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 496.0
HKD2_k127_2711798_10 - - - - 0.000000000000000000000000003458 115.0
HKD2_k127_2711798_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.000000000000000000000002957 103.0
HKD2_k127_2711798_12 Nitroreductase family - - - 0.0000000000000000000837 93.0
HKD2_k127_2711798_15 Transposase (IS116 IS110 IS902 family) - - - 0.0000004257 52.0
HKD2_k127_2711798_2 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 389.0
HKD2_k127_2711798_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 403.0
HKD2_k127_2711798_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 316.0
HKD2_k127_2711798_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 303.0
HKD2_k127_2711798_6 Crp Fnr family K01420,K15861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
HKD2_k127_2711798_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000003952 212.0
HKD2_k127_2711798_8 Nitroreductase family - - - 0.0000000000000000000000000000000000000002372 152.0
HKD2_k127_2711798_9 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000002665 151.0
HKD2_k127_2715839_0 PFAM AMP-dependent synthetase and ligase K04110 - 6.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 577.0
HKD2_k127_2715839_1 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 561.0
HKD2_k127_2715839_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 370.0
HKD2_k127_2715839_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 364.0
HKD2_k127_2715839_4 COG0411 ABC-type branched-chain amino acid transport systems ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 313.0
HKD2_k127_2715839_5 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000125 265.0
HKD2_k127_2715839_6 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000001276 144.0
HKD2_k127_2715839_7 Carbon monoxide dehydrogenase subunit G (CoxG) K16877 - 1.3.99.8 0.00000000000000000000000000001505 121.0
HKD2_k127_2715839_8 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component K11690 - - 0.00000000000000000114 87.0
HKD2_k127_2740870_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1044.0
HKD2_k127_2740870_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 8.504e-286 892.0
HKD2_k127_2740870_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 297.0
HKD2_k127_2740870_11 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008122 252.0
HKD2_k127_2740870_12 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000007391 250.0
HKD2_k127_2740870_14 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000003891 173.0
HKD2_k127_2740870_15 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000009776 182.0
HKD2_k127_2740870_16 - - - - 0.00000000000000000000000000000000000000000002072 177.0
HKD2_k127_2740870_17 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000005113 154.0
HKD2_k127_2740870_18 SPW repeat - - - 0.00000000000000000000000000000001849 132.0
HKD2_k127_2740870_19 SnoaL-like domain - - - 0.0000000000000000000000000000003174 126.0
HKD2_k127_2740870_2 Sugar (and other) transporter - - - 4.831e-238 750.0
HKD2_k127_2740870_20 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000001912 126.0
HKD2_k127_2740870_21 - - - - 0.00000000000000000000000000009699 119.0
HKD2_k127_2740870_22 - - - - 0.00000000000000000000001998 102.0
HKD2_k127_2740870_23 - - - - 0.000000000000000000004484 100.0
HKD2_k127_2740870_24 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000007486 74.0
HKD2_k127_2740870_25 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K16079 - - 0.000000001394 62.0
HKD2_k127_2740870_28 - - - - 0.0008576 48.0
HKD2_k127_2740870_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 9.066e-226 710.0
HKD2_k127_2740870_4 Peptidogalycan biosysnthesis/recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 497.0
HKD2_k127_2740870_5 Amidohydrolase K07045,K14333,K15063,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 428.0
HKD2_k127_2740870_6 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 424.0
HKD2_k127_2740870_7 Sel1-like repeats. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 379.0
HKD2_k127_2740870_8 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 370.0
HKD2_k127_2740870_9 methyltransferase activity K00223,K21310 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.3.1.71,2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 322.0
HKD2_k127_2859906_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 567.0
HKD2_k127_2859906_1 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000001176 89.0
HKD2_k127_2860897_0 enoyl-CoA hydratase isomerase K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 1.868e-289 903.0
HKD2_k127_2860897_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 4.557e-228 722.0
HKD2_k127_2860897_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000001786 141.0
HKD2_k127_2860897_3 Putative ParB-like nuclease - - - 0.0000008969 51.0
HKD2_k127_2868516_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 6.61e-280 866.0
HKD2_k127_2868711_0 Histidine kinase K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 565.0
HKD2_k127_2868711_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 299.0
HKD2_k127_2868711_2 response regulator K14987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002578 258.0
HKD2_k127_2868711_3 Crp Fnr family K01420,K15861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001387 257.0
HKD2_k127_2868711_4 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000009273 180.0
HKD2_k127_2868711_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000005192 75.0
HKD2_k127_2999974_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 521.0
HKD2_k127_2999974_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 400.0
HKD2_k127_2999974_2 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 305.0
HKD2_k127_2999974_3 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006824 251.0
HKD2_k127_2999974_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000004583 151.0
HKD2_k127_3023925_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1677.0
HKD2_k127_3023925_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 484.0
HKD2_k127_3023925_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 289.0
HKD2_k127_3126721_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6e-254 786.0
HKD2_k127_3126721_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 GO:0003674,GO:0003824,GO:0008410,GO:0016740,GO:0016782,GO:0047369 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 537.0
HKD2_k127_3126721_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 525.0
HKD2_k127_3126721_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 281.0
HKD2_k127_3126721_4 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000003544 254.0
HKD2_k127_3126721_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000002048 93.0
HKD2_k127_315697_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1244.0
HKD2_k127_315697_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 1.484e-209 659.0
HKD2_k127_315697_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 451.0
HKD2_k127_315697_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000411 272.0
HKD2_k127_315697_4 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000003104 197.0
HKD2_k127_315697_5 Rare lipoprotein A - - - 0.000000000000000000000000005757 119.0
HKD2_k127_3188537_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 5.095e-313 966.0
HKD2_k127_32013_0 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 609.0
HKD2_k127_32013_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 540.0
HKD2_k127_32013_2 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001741 286.0
HKD2_k127_32013_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000421 184.0
HKD2_k127_32013_4 DNA repair protein MmcB-like - - - 0.0000000000000000000000000005474 118.0
HKD2_k127_3247815_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 5.028e-294 911.0
HKD2_k127_3247815_1 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000102 175.0
HKD2_k127_3247815_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000003068 99.0
HKD2_k127_326199_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.496e-255 796.0
HKD2_k127_326199_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 525.0
HKD2_k127_326199_2 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000001803 236.0
HKD2_k127_326199_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000004195 210.0
HKD2_k127_326199_4 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000001362 185.0
HKD2_k127_326199_5 Thiamine pyrophosphate enzyme, central domain K03852 - 2.3.3.15 0.0000000000000000000000000000000000005021 139.0
HKD2_k127_332707_0 Hydrolase CocE NonD family K06978 - - 8.267e-290 899.0
HKD2_k127_332707_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 375.0
HKD2_k127_332707_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000313 258.0
HKD2_k127_332707_11 Glutathione S-transferase, N-terminal domain K01800 - 5.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000356 247.0
HKD2_k127_332707_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005311 249.0
HKD2_k127_332707_13 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002883 250.0
HKD2_k127_332707_14 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000055 240.0
HKD2_k127_332707_15 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000133 205.0
HKD2_k127_332707_16 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000004791 181.0
HKD2_k127_332707_17 NMT1-like family K02051,K15553 - - 0.00000000000000000000000000000000001928 147.0
HKD2_k127_332707_18 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.0003381 48.0
HKD2_k127_332707_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 357.0
HKD2_k127_332707_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 356.0
HKD2_k127_332707_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 332.0
HKD2_k127_332707_5 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 316.0
HKD2_k127_332707_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 309.0
HKD2_k127_332707_7 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 296.0
HKD2_k127_332707_8 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000288 289.0
HKD2_k127_332707_9 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009854 274.0
HKD2_k127_335762_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1480.0
HKD2_k127_335762_1 Biotin carboxylase C-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.239e-252 783.0
HKD2_k127_335762_10 Dehydrogenase - - - 0.00000000000001522 76.0
HKD2_k127_335762_2 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 374.0
HKD2_k127_335762_3 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 367.0
HKD2_k127_335762_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 346.0
HKD2_k127_335762_5 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000727 254.0
HKD2_k127_335762_6 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001014 254.0
HKD2_k127_335762_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000001473 213.0
HKD2_k127_335762_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000000000000000002344 188.0
HKD2_k127_335762_9 cheY-homologous receiver domain - - - 0.0000000000000000000008993 100.0
HKD2_k127_3375215_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0 1209.0
HKD2_k127_3375215_1 Penicillin-binding Protein K03587 - 3.4.16.4 1.336e-278 868.0
HKD2_k127_3375215_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 610.0
HKD2_k127_3375215_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 608.0
HKD2_k127_3375215_12 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 561.0
HKD2_k127_3375215_13 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 549.0
HKD2_k127_3375215_14 Belongs to the D-alanine--D-alanine ligase family K00075,K01921 - 1.3.1.98,6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 460.0
HKD2_k127_3375215_15 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 456.0
HKD2_k127_3375215_16 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 428.0
HKD2_k127_3375215_17 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 424.0
HKD2_k127_3375215_18 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 429.0
HKD2_k127_3375215_19 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 422.0
HKD2_k127_3375215_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 6.039e-261 818.0
HKD2_k127_3375215_20 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 414.0
HKD2_k127_3375215_21 N-acetylmuramoyl-L-alanine amidase (Family 2) K01447,K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 345.0
HKD2_k127_3375215_22 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 313.0
HKD2_k127_3375215_23 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002247 289.0
HKD2_k127_3375215_24 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009509 281.0
HKD2_k127_3375215_25 Essential cell division protein K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 277.0
HKD2_k127_3375215_26 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000004004 237.0
HKD2_k127_3375215_27 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000001758 226.0
HKD2_k127_3375215_28 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000004757 213.0
HKD2_k127_3375215_29 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000001748 193.0
HKD2_k127_3375215_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.387e-251 780.0
HKD2_k127_3375215_30 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000006653 191.0
HKD2_k127_3375215_31 - - - - 0.00000000000000000000000000000000000000000000007296 174.0
HKD2_k127_3375215_32 PFAM PRC-barrel domain - - - 0.00000000000000000000000000000000002609 142.0
HKD2_k127_3375215_33 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000000000000000000000005071 137.0
HKD2_k127_3375215_34 secreted (periplasmic) protein - - - 0.00000000000000000000000000000001001 130.0
HKD2_k127_3375215_35 - - - - 0.000000000000000000000000000006397 120.0
HKD2_k127_3375215_37 - - - - 0.000000000000000001259 95.0
HKD2_k127_3375215_38 - - - - 0.000000000000000001491 88.0
HKD2_k127_3375215_4 May be involved in recombinational repair of damaged DNA K03631 - - 3.445e-242 759.0
HKD2_k127_3375215_40 Bacterial protein of unknown function (DUF937) - - - 0.000000000002365 68.0
HKD2_k127_3375215_41 - - - - 0.0000000004698 64.0
HKD2_k127_3375215_42 peptidase inhibitor activity - - - 0.00000001941 61.0
HKD2_k127_3375215_43 Pfam:Pyridox_oxidase K07006 - - 0.00000003489 61.0
HKD2_k127_3375215_44 CHASE2 - - - 0.0000009366 52.0
HKD2_k127_3375215_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 2.4e-237 747.0
HKD2_k127_3375215_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.091e-211 663.0
HKD2_k127_3375215_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 7.874e-198 629.0
HKD2_k127_3375215_8 Protein kinase domain - - - 3.939e-195 621.0
HKD2_k127_3375215_9 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 605.0
HKD2_k127_3377566_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1293.0
HKD2_k127_3377566_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 578.0
HKD2_k127_3378853_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 589.0
HKD2_k127_3378853_1 OmpA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 317.0
HKD2_k127_3378853_2 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001789 272.0
HKD2_k127_3378853_3 - - - - 0.000000000000000000000000000000000000000000000000006549 186.0
HKD2_k127_33832_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 572.0
HKD2_k127_33832_1 peptidase, M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 561.0
HKD2_k127_33832_10 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
HKD2_k127_33832_11 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 371.0
HKD2_k127_33832_12 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 364.0
HKD2_k127_33832_13 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008434 280.0
HKD2_k127_33832_14 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000001272 206.0
HKD2_k127_33832_15 oxidation-reduction process - - - 0.000000000000000000000000000000000000000002158 158.0
HKD2_k127_33832_16 - - - - 0.00000000000002999 77.0
HKD2_k127_33832_2 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 546.0
HKD2_k127_33832_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 470.0
HKD2_k127_33832_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 421.0
HKD2_k127_33832_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 416.0
HKD2_k127_33832_6 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 401.0
HKD2_k127_33832_7 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 404.0
HKD2_k127_33832_8 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 386.0
HKD2_k127_33832_9 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 379.0
HKD2_k127_3420989_0 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 452.0
HKD2_k127_3420989_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 312.0
HKD2_k127_3420989_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000007597 131.0
HKD2_k127_3440231_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 2.136e-261 811.0
HKD2_k127_3440231_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 2.202e-233 731.0
HKD2_k127_3440231_10 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001364 269.0
HKD2_k127_3440231_11 Polyketide cyclase / dehydrase and lipid transport K18588 - - 0.0000000000000000000000000000000000000000000000000000000000000000002583 231.0
HKD2_k127_3440231_12 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000134 235.0
HKD2_k127_3440231_13 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000002748 191.0
HKD2_k127_3440231_14 cell cycle - - - 0.00000000000000000000000000001049 121.0
HKD2_k127_3440231_15 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000004931 109.0
HKD2_k127_3440231_16 Transglycosylase associated protein - - - 0.0000000000000000009461 89.0
HKD2_k127_3440231_17 - - - - 0.00000000005502 68.0
HKD2_k127_3440231_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.912e-226 705.0
HKD2_k127_3440231_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 594.0
HKD2_k127_3440231_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 576.0
HKD2_k127_3440231_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 552.0
HKD2_k127_3440231_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 550.0
HKD2_k127_3440231_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 524.0
HKD2_k127_3440231_8 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 457.0
HKD2_k127_3440231_9 Methyltransferase fkbm family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 409.0
HKD2_k127_3451062_0 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 537.0
HKD2_k127_3451062_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 449.0
HKD2_k127_3451062_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 314.0
HKD2_k127_3451062_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000001645 233.0
HKD2_k127_3451062_4 Putative beta-barrel porin 2 - - - 0.000004449 53.0
HKD2_k127_3503951_0 domain, Protein - - - 9.257e-197 633.0
HKD2_k127_3503951_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 457.0
HKD2_k127_3503951_10 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) - - - 0.00000009404 62.0
HKD2_k127_3503951_11 TRAP transporter, 4TM 12TM fusion protein - - - 0.000008685 55.0
HKD2_k127_3503951_2 mandelate racemase muconate lactonizing K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
HKD2_k127_3503951_3 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 396.0
HKD2_k127_3503951_4 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004393 278.0
HKD2_k127_3503951_5 TRAP transporter, solute receptor (TAXI family - - - 0.000000000000000000000000000000000000000000009177 169.0
HKD2_k127_3503951_6 - - - - 0.00000000000000000000000000000000000000000006414 165.0
HKD2_k127_3503951_7 Pyridoxal-phosphate dependent enzyme K01754 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.00000000000000000000000000000000000002442 145.0
HKD2_k127_3503951_8 TRAP transporter, solute receptor (TAXI family - - - 0.0000000000000000002025 90.0
HKD2_k127_3503951_9 TRAP transporter, solute receptor (TAXI family - - - 0.000000000000005589 81.0
HKD2_k127_3546289_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1088.0
HKD2_k127_3546289_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 3.697e-196 615.0
HKD2_k127_3546289_2 Carboxyl transferase domain K01966 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0031974,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0070013,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 568.0
HKD2_k127_3546289_3 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 384.0
HKD2_k127_3546289_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K17722 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 350.0
HKD2_k127_3546289_5 COG2116 Formate nitrite family of transporters K21990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
HKD2_k127_3546289_6 ATP12 chaperone protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 286.0
HKD2_k127_3546289_7 DNA-binding ferritin-like protein (Oxidative damage protectant) K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 247.0
HKD2_k127_3546289_8 Domain of unknown function (DUF4260) - - - 0.0000000000000000000000000000000000000001004 158.0
HKD2_k127_3546289_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001931 142.0
HKD2_k127_381562_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0 1083.0
HKD2_k127_381562_1 NADH-ubiquinone oxidoreductase chain 4, amino terminus K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 2.933e-261 811.0
HKD2_k127_381562_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 555.0
HKD2_k127_381562_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 299.0
HKD2_k127_381562_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000008671 170.0
HKD2_k127_381562_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000001884 93.0
HKD2_k127_3835067_0 FAD linked oxidases, C-terminal domain K00102 GO:0000166,GO:0003674,GO:0003824,GO:0004457,GO:0004458,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006089,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016053,GO:0016491,GO:0016614,GO:0016898,GO:0019249,GO:0019516,GO:0019752,GO:0022900,GO:0022904,GO:0030447,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046394,GO:0048037,GO:0050660,GO:0050662,GO:0051990,GO:0055114,GO:0071704,GO:0071949,GO:0072330,GO:0097159,GO:0099615,GO:1901265,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 624.0
HKD2_k127_3835067_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 407.0
HKD2_k127_3835067_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000005097 162.0
HKD2_k127_3856746_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1165.0
HKD2_k127_3856746_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1097.0
HKD2_k127_3856746_10 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001862 256.0
HKD2_k127_3856746_11 Membrane-associated sensor, integral membrane domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 257.0
HKD2_k127_3856746_12 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000007353 237.0
HKD2_k127_3856746_13 - - - - 0.0000000000000000000000000000000000000000000000681 172.0
HKD2_k127_3856746_14 PFAM DoxX K15977 - - 0.0000000000000000000000000000000000000000001683 164.0
HKD2_k127_3856746_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000001934 160.0
HKD2_k127_3856746_16 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000007831 160.0
HKD2_k127_3856746_17 KR domain - - - 0.000000000000000000000000000000003167 130.0
HKD2_k127_3856746_18 OmpA-like transmembrane domain - - - 0.000000000000000000000000000000009822 135.0
HKD2_k127_3856746_19 - - - - 0.00000000000000000000002418 104.0
HKD2_k127_3856746_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 3.445e-216 682.0
HKD2_k127_3856746_20 - - - - 0.00000000000000000000008478 102.0
HKD2_k127_3856746_21 - - - - 0.0000000000000000001208 97.0
HKD2_k127_3856746_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.554e-213 677.0
HKD2_k127_3856746_4 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 599.0
HKD2_k127_3856746_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 524.0
HKD2_k127_3856746_6 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 431.0
HKD2_k127_3856746_7 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 415.0
HKD2_k127_3856746_8 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006255 275.0
HKD2_k127_3856746_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009077 274.0
HKD2_k127_3878444_0 - - - - 0.0 1154.0
HKD2_k127_3878444_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.031e-259 811.0
HKD2_k127_3878444_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02017,K02052 - 3.6.3.29,3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 441.0
HKD2_k127_3878444_3 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005523 246.0
HKD2_k127_3878444_4 ABC-type Fe3 transport system, periplasmic K02012 - - 0.00000000000000000000001077 108.0
HKD2_k127_3878444_5 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00001992 49.0
HKD2_k127_3880225_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1458.0
HKD2_k127_3880225_1 Domain of unknown function (DUF4175) - - - 1.062e-302 950.0
HKD2_k127_3880225_10 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 411.0
HKD2_k127_3880225_11 ATPases associated with a variety of cellular activities K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 396.0
HKD2_k127_3880225_12 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 394.0
HKD2_k127_3880225_13 Chorismate mutase type II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 370.0
HKD2_k127_3880225_14 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 369.0
HKD2_k127_3880225_15 methionine biosynthesis protein (MetW) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 349.0
HKD2_k127_3880225_16 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 340.0
HKD2_k127_3880225_17 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 341.0
HKD2_k127_3880225_18 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 296.0
HKD2_k127_3880225_19 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 294.0
HKD2_k127_3880225_2 Peptidase family M23 - - - 7.129e-280 875.0
HKD2_k127_3880225_20 electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001619 266.0
HKD2_k127_3880225_21 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000005454 265.0
HKD2_k127_3880225_22 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001024 264.0
HKD2_k127_3880225_23 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
HKD2_k127_3880225_24 CHAP domain - - - 0.00000000000000000000000000000000000000000000003348 177.0
HKD2_k127_3880225_25 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000004992 185.0
HKD2_k127_3880225_26 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000009757 162.0
HKD2_k127_3880225_27 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000001642 152.0
HKD2_k127_3880225_28 TIGRFAM MJ0042 family finger-like protein - - - 0.0000000000000000000000000000008923 132.0
HKD2_k127_3880225_29 Hypoxia induced protein conserved region - - - 0.000000000000000000006122 93.0
HKD2_k127_3880225_3 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.725e-236 740.0
HKD2_k127_3880225_31 Prokaryotic lipoprotein-attachment site - - - 0.0006148 46.0
HKD2_k127_3880225_33 Putative motility protein - - - 0.0009174 44.0
HKD2_k127_3880225_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 2.44e-208 653.0
HKD2_k127_3880225_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 3.408e-206 651.0
HKD2_k127_3880225_6 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 563.0
HKD2_k127_3880225_7 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 504.0
HKD2_k127_3880225_8 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 501.0
HKD2_k127_3880225_9 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 492.0
HKD2_k127_3881876_0 Beta-agarase K01219 - 3.2.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 415.0
HKD2_k127_3881876_1 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 353.0
HKD2_k127_3900883_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1046.0
HKD2_k127_3907233_0 Sigma-54 interaction domain K07712 - - 4.126e-270 835.0
HKD2_k127_3907233_1 His Kinase A (phosphoacceptor) domain K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 601.0
HKD2_k127_3907233_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 452.0
HKD2_k127_3907233_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000604 105.0
HKD2_k127_3907233_4 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000006071 94.0
HKD2_k127_3908412_0 PFAM Xanthine uracil vitamin C permease K06901 - - 3.314e-198 625.0
HKD2_k127_3908412_1 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000003528 67.0
HKD2_k127_3916410_0 Phosphopantetheine attachment site K00666 - - 0.0 1212.0
HKD2_k127_3916410_1 acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 552.0
HKD2_k127_3916410_2 of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 501.0
HKD2_k127_3916410_3 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 430.0
HKD2_k127_3916410_4 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000001532 210.0
HKD2_k127_3916410_5 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000000000000000000000007956 195.0
HKD2_k127_3916410_6 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.00000000000000000000000000000000000000000000000002154 184.0
HKD2_k127_3916410_7 Uncharacterized conserved protein (DUF2267) - - - 0.00000000000000000000000000000000000000000001979 166.0
HKD2_k127_3916410_8 tRNA modification K06968 - 2.1.1.186 0.0000000000000000000000000000000000000000003159 164.0
HKD2_k127_3924670_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 516.0
HKD2_k127_3924670_1 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 387.0
HKD2_k127_3925420_0 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001665 280.0
HKD2_k127_3925420_1 Colicin V production protein K03558 - - 0.000000000000000000000000000000002519 136.0
HKD2_k127_3925420_2 - - - - 0.000000000000000000001226 97.0
HKD2_k127_3933357_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 330.0
HKD2_k127_3933357_1 Binding-protein-dependent transport system inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000004174 154.0
HKD2_k127_3933357_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000004494 155.0
HKD2_k127_3933357_3 NMT1-like family K02051 - - 0.00000000000000007555 92.0
HKD2_k127_3933357_4 Chromate resistance exported protein - - - 0.00000000009996 62.0
HKD2_k127_3933357_5 Major Facilitator Superfamily - - - 0.0000000001896 71.0
HKD2_k127_394672_0 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 512.0
HKD2_k127_394672_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 491.0
HKD2_k127_394672_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000001668 66.0
HKD2_k127_3952232_0 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 502.0
HKD2_k127_3952232_1 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 366.0
HKD2_k127_3959609_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 573.0
HKD2_k127_3959609_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000001279 148.0
HKD2_k127_3959609_2 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000005847 107.0
HKD2_k127_3988639_0 FtsX-like permease family K02004 - - 5.636e-222 696.0
HKD2_k127_3988639_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000001832 240.0
HKD2_k127_3988639_2 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000005719 114.0
HKD2_k127_3995759_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 9.183e-223 703.0
HKD2_k127_3995759_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 528.0
HKD2_k127_3995759_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 529.0
HKD2_k127_3995759_3 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 435.0
HKD2_k127_3995759_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000002928 178.0
HKD2_k127_3995759_5 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000001005 151.0
HKD2_k127_4006313_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.356e-237 739.0
HKD2_k127_4006313_1 Aminotransferase class-III K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 583.0
HKD2_k127_4006313_10 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004355 273.0
HKD2_k127_4006313_11 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006277 274.0
HKD2_k127_4006313_12 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.00000000000000000000000000000000000000000000000000000000000000000000003839 246.0
HKD2_k127_4006313_13 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000127 226.0
HKD2_k127_4006313_14 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000004165 158.0
HKD2_k127_4006313_15 Urate oxidase N-terminal - - - 0.0000000000000000000000002353 109.0
HKD2_k127_4006313_16 AMP-binding enzyme C-terminal domain - - - 0.0000000000001963 76.0
HKD2_k127_4006313_17 Phage integrase, N-terminal SAM-like domain - - - 0.000000001003 61.0
HKD2_k127_4006313_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 539.0
HKD2_k127_4006313_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 502.0
HKD2_k127_4006313_4 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 494.0
HKD2_k127_4006313_5 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 434.0
HKD2_k127_4006313_6 FAD binding domain K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 429.0
HKD2_k127_4006313_7 Aspartyl Asparaginyl beta-hydroxylase K00476,K12979 - 1.14.11.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 406.0
HKD2_k127_4006313_8 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 317.0
HKD2_k127_4006313_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 271.0
HKD2_k127_4017576_0 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 546.0
HKD2_k127_4017576_1 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 327.0
HKD2_k127_4017576_2 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000005802 162.0
HKD2_k127_4017576_3 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0004591 45.0
HKD2_k127_4025764_0 MMPL family K03296 - - 0.0 1498.0
HKD2_k127_4025764_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.124e-281 874.0
HKD2_k127_4025764_10 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 414.0
HKD2_k127_4025764_11 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 422.0
HKD2_k127_4025764_12 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 404.0
HKD2_k127_4025764_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 407.0
HKD2_k127_4025764_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 400.0
HKD2_k127_4025764_15 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 384.0
HKD2_k127_4025764_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 361.0
HKD2_k127_4025764_17 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 365.0
HKD2_k127_4025764_18 2-keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 357.0
HKD2_k127_4025764_19 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006836 331.0
HKD2_k127_4025764_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 1.391e-252 789.0
HKD2_k127_4025764_20 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 288.0
HKD2_k127_4025764_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002073 280.0
HKD2_k127_4025764_22 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000498 284.0
HKD2_k127_4025764_23 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000003387 261.0
HKD2_k127_4025764_24 PFAM MaoC domain protein dehydratase K17865 GO:0003674,GO:0003824,GO:0003859,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0046487,GO:0071704 4.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000811 247.0
HKD2_k127_4025764_25 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000000000002921 242.0
HKD2_k127_4025764_26 COG1562 Phytoene squalene synthetase K02291,K18163 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000001676 236.0
HKD2_k127_4025764_27 Sporulation related domain - - - 0.00000000000000000000000000000000000000000000000000000000008592 222.0
HKD2_k127_4025764_28 - - - - 0.000000000000000000000000000000000000000000000000003882 188.0
HKD2_k127_4025764_29 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002359 186.0
HKD2_k127_4025764_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 2.492e-231 724.0
HKD2_k127_4025764_30 Belongs to the HesB IscA family K13628,K15724 - - 0.000000000000000000000000000000000000000000000001347 177.0
HKD2_k127_4025764_31 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000000000001169 171.0
HKD2_k127_4025764_32 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000005356 154.0
HKD2_k127_4025764_33 Response regulator receiver - - - 0.00000000000000000000000000000000000226 141.0
HKD2_k127_4025764_34 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.000000000000000000000000000003805 124.0
HKD2_k127_4025764_35 Carboxymethylenebutenolidase K01061 - 3.1.1.45 0.00000000000000000000000000000431 128.0
HKD2_k127_4025764_36 antibiotic catabolic process - - - 0.0000000000000000000000000001519 122.0
HKD2_k127_4025764_37 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000001705 110.0
HKD2_k127_4025764_38 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.000000000000000000008191 94.0
HKD2_k127_4025764_39 - - - - 0.00000000000000000005627 91.0
HKD2_k127_4025764_4 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.698e-203 642.0
HKD2_k127_4025764_41 - - - - 0.000000000008435 70.0
HKD2_k127_4025764_43 Domain of unknown function (DUF1127) - - - 0.0000000003214 61.0
HKD2_k127_4025764_5 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 1.012e-201 644.0
HKD2_k127_4025764_6 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 529.0
HKD2_k127_4025764_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 499.0
HKD2_k127_4025764_8 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 462.0
HKD2_k127_4025764_9 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 447.0
HKD2_k127_405368_0 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 413.0
HKD2_k127_405368_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 399.0
HKD2_k127_405368_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001841 274.0
HKD2_k127_405368_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000322 166.0
HKD2_k127_4142152_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.218e-297 919.0
HKD2_k127_415899_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 337.0
HKD2_k127_415899_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003255 269.0
HKD2_k127_415899_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001628 245.0
HKD2_k127_4168063_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 1.214e-249 775.0
HKD2_k127_4168063_1 Amidohydrolase family K01465 - 3.5.2.3 8.116e-231 720.0
HKD2_k127_4168063_10 protein tyrosine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000003361 221.0
HKD2_k127_4168063_11 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000002373 228.0
HKD2_k127_4168063_12 Protein of unknown function (DUF2385) - - - 0.00000000000000000000000000000000000000000000000000003692 191.0
HKD2_k127_4168063_13 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000004794 188.0
HKD2_k127_4168063_14 NUDIX domain - - - 0.000000000000000000000000000000000000000000000001847 177.0
HKD2_k127_4168063_15 - - - - 0.00000000000000000000000000000000000000000002195 166.0
HKD2_k127_4168063_16 - - - - 0.00000000000000000000000000000000000000004854 157.0
HKD2_k127_4168063_17 - - - - 0.000000000000000000000000000002702 123.0
HKD2_k127_4168063_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 576.0
HKD2_k127_4168063_3 Zinc-binding dehydrogenase K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 506.0
HKD2_k127_4168063_4 Cell Wall Hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 411.0
HKD2_k127_4168063_5 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 339.0
HKD2_k127_4168063_6 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 338.0
HKD2_k127_4168063_7 glycosylase i K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 332.0
HKD2_k127_4168063_8 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 283.0
HKD2_k127_4168063_9 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002298 257.0
HKD2_k127_4186921_0 Belongs to the 5'-nucleotidase family K17224 - - 6.721e-274 852.0
HKD2_k127_4186921_1 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 516.0
HKD2_k127_4186921_10 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000001355 176.0
HKD2_k127_4186921_11 Regulatory protein SoxS - - - 0.0000000000000000000000000000000007026 136.0
HKD2_k127_4186921_12 PFAM regulatory protein ArsR - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000001509 115.0
HKD2_k127_4186921_13 - - - - 0.000000000000000000000000002573 121.0
HKD2_k127_4186921_2 Cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 516.0
HKD2_k127_4186921_3 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 500.0
HKD2_k127_4186921_4 COG2041 Sulfite oxidase and related enzymes K17225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 463.0
HKD2_k127_4186921_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003304 277.0
HKD2_k127_4186921_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007341 266.0
HKD2_k127_4186921_7 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001139 242.0
HKD2_k127_4186921_8 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.00000000000000000000000000000000000000000000000000000008725 207.0
HKD2_k127_4186921_9 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000000002206 174.0
HKD2_k127_4214450_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 531.0
HKD2_k127_4214450_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003953 266.0
HKD2_k127_4214450_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008634 241.0
HKD2_k127_4214450_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008808 240.0
HKD2_k127_4214450_4 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000008949 249.0
HKD2_k127_425053_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 599.0
HKD2_k127_425053_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 417.0
HKD2_k127_425053_10 Protein of unknown function (DUF1236) - - - 0.00000015 58.0
HKD2_k127_425053_11 Protein of unknown function (DUF3072) - - - 0.0001465 50.0
HKD2_k127_425053_2 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000004546 195.0
HKD2_k127_425053_3 - - - - 0.0000000000000000000000000000000000000000000000000004257 191.0
HKD2_k127_425053_4 MaoC like domain - - - 0.000000000000000000000000000000000000000000000005821 177.0
HKD2_k127_425053_5 - - - - 0.0000000000000000000001778 104.0
HKD2_k127_425053_6 - - - - 0.00000000000000000002361 95.0
HKD2_k127_425053_7 - - - - 0.00000000000001639 78.0
HKD2_k127_425053_8 - - - - 0.00000000001573 76.0
HKD2_k127_4310930_0 Periplasmic binding protein domain K01999 - - 2.393e-201 633.0
HKD2_k127_4310930_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 552.0
HKD2_k127_4310930_2 Protein of unknown function (DUF1445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 404.0
HKD2_k127_4310930_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 251.0
HKD2_k127_43810_0 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0006072,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 474.0
HKD2_k127_43810_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 470.0
HKD2_k127_43810_2 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000005579 198.0
HKD2_k127_43810_3 Protein of unknown function (DUF1761) - - - 0.0000003779 53.0
HKD2_k127_4430898_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.11e-255 790.0
HKD2_k127_4430898_1 AAA C-terminal domain K07478 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0030894,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 2.448e-233 729.0
HKD2_k127_4430898_10 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 346.0
HKD2_k127_4430898_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 331.0
HKD2_k127_4430898_12 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 291.0
HKD2_k127_4430898_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007322 276.0
HKD2_k127_4430898_14 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001963 271.0
HKD2_k127_4430898_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000003955 241.0
HKD2_k127_4430898_16 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000006187 235.0
HKD2_k127_4430898_17 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002918 227.0
HKD2_k127_4430898_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000005158 227.0
HKD2_k127_4430898_19 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001533 223.0
HKD2_k127_4430898_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 1.274e-207 647.0
HKD2_k127_4430898_20 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000452 218.0
HKD2_k127_4430898_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001225 213.0
HKD2_k127_4430898_22 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001671 204.0
HKD2_k127_4430898_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006014 200.0
HKD2_k127_4430898_24 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000006238 179.0
HKD2_k127_4430898_25 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000003856 171.0
HKD2_k127_4430898_26 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000003524 164.0
HKD2_k127_4430898_27 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000167 165.0
HKD2_k127_4430898_28 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001135 158.0
HKD2_k127_4430898_29 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000006097 136.0
HKD2_k127_4430898_3 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 8.494e-207 655.0
HKD2_k127_4430898_30 ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000005079 96.0
HKD2_k127_4430898_31 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000006403 96.0
HKD2_k127_4430898_4 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 537.0
HKD2_k127_4430898_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 452.0
HKD2_k127_4430898_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 429.0
HKD2_k127_4430898_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 418.0
HKD2_k127_4430898_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 400.0
HKD2_k127_4430898_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 387.0
HKD2_k127_4612196_0 FtsX-like permease family K02004 - - 0.0 1088.0
HKD2_k127_4612196_1 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 509.0
HKD2_k127_4612196_2 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 432.0
HKD2_k127_4612196_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007366 270.0
HKD2_k127_4612196_5 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00001315 51.0
HKD2_k127_4612196_6 VIT family - - - 0.0004395 45.0
HKD2_k127_4728650_0 Alpha-2-Macroglobulin K06894 - - 0.0 2242.0
HKD2_k127_4728650_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.154e-266 839.0
HKD2_k127_4728650_10 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 462.0
HKD2_k127_4728650_11 ATPases associated with a variety of cellular activities K02028,K09972 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 452.0
HKD2_k127_4728650_12 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 370.0
HKD2_k127_4728650_13 Rhodanese Homology Domain K01011 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016782,GO:0016783,GO:0016784,GO:0031668,GO:0033554,GO:0034641,GO:0042221,GO:0042262,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 353.0
HKD2_k127_4728650_14 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 326.0
HKD2_k127_4728650_15 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 330.0
HKD2_k127_4728650_16 Threonyl and Alanyl tRNA synthetase second additional domain K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 316.0
HKD2_k127_4728650_17 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 312.0
HKD2_k127_4728650_18 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 289.0
HKD2_k127_4728650_19 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 287.0
HKD2_k127_4728650_2 glycosyl transferase, family 39 - - - 9.216e-215 682.0
HKD2_k127_4728650_20 O-methyltransferase activity K05303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000085 273.0
HKD2_k127_4728650_21 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001692 262.0
HKD2_k127_4728650_22 phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000005384 207.0
HKD2_k127_4728650_23 Lipid A Biosynthesis N-terminal domain - - - 0.00000000000000000000000000000000000000000007144 161.0
HKD2_k127_4728650_24 GGDEF domain - - - 0.000000000000000000000000000000000000001239 156.0
HKD2_k127_4728650_3 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 600.0
HKD2_k127_4728650_4 cystathionine beta-lyase K01760 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 572.0
HKD2_k127_4728650_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 562.0
HKD2_k127_4728650_6 amino acid ABC transporter K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 530.0
HKD2_k127_4728650_7 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 521.0
HKD2_k127_4728650_8 Binding-protein-dependent transport system inner membrane component K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 503.0
HKD2_k127_4728650_9 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 484.0
HKD2_k127_5112659_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 6.946e-220 692.0
HKD2_k127_5112659_1 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 447.0
HKD2_k127_5112659_10 OstA-like protein K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000002152 228.0
HKD2_k127_5112659_11 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000000000000001992 219.0
HKD2_k127_5112659_12 Protein of unknown function (DUF1150) - - - 0.0000000000000000000000000000000003296 133.0
HKD2_k127_5112659_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000007618 122.0
HKD2_k127_5112659_14 Belongs to the 'phage' integrase family - - - 0.00006198 49.0
HKD2_k127_5112659_2 ATPases associated with a variety of cellular activities K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 426.0
HKD2_k127_5112659_3 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 427.0
HKD2_k127_5112659_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 405.0
HKD2_k127_5112659_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 355.0
HKD2_k127_5112659_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 341.0
HKD2_k127_5112659_7 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 322.0
HKD2_k127_5112659_8 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006919 246.0
HKD2_k127_5112659_9 PTS IIA-like nitrogen-regulatory protein PtsN K02806 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 - 0.00000000000000000000000000000000000000000000000000000000000000000000001687 244.0
HKD2_k127_5121463_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1254.0
HKD2_k127_5121463_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1241.0
HKD2_k127_5121463_10 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 510.0
HKD2_k127_5121463_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 503.0
HKD2_k127_5121463_12 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 498.0
HKD2_k127_5121463_13 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 493.0
HKD2_k127_5121463_14 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 470.0
HKD2_k127_5121463_15 Branched-chain amino acid ATP-binding cassette transporter K01995,K15783 GO:0003333,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015808,GO:0015818,GO:0015829,GO:0015849,GO:0015893,GO:0032328,GO:0034220,GO:0042221,GO:0042493,GO:0042940,GO:0042941,GO:0043090,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903805,GO:1903806,GO:1903825,GO:1905039 3.5.4.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 456.0
HKD2_k127_5121463_16 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 448.0
HKD2_k127_5121463_17 COG1226 Kef-type K transport systems K10716 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 449.0
HKD2_k127_5121463_18 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 448.0
HKD2_k127_5121463_19 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 395.0
HKD2_k127_5121463_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 1.273e-234 736.0
HKD2_k127_5121463_20 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 396.0
HKD2_k127_5121463_21 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
HKD2_k127_5121463_22 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 357.0
HKD2_k127_5121463_23 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 361.0
HKD2_k127_5121463_24 helix_turn_helix, arabinose operon control protein K18954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 340.0
HKD2_k127_5121463_25 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 333.0
HKD2_k127_5121463_26 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 329.0
HKD2_k127_5121463_27 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 336.0
HKD2_k127_5121463_28 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 322.0
HKD2_k127_5121463_29 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 322.0
HKD2_k127_5121463_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.062e-231 721.0
HKD2_k127_5121463_30 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 317.0
HKD2_k127_5121463_31 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 297.0
HKD2_k127_5121463_32 membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002615 281.0
HKD2_k127_5121463_33 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 273.0
HKD2_k127_5121463_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002233 252.0
HKD2_k127_5121463_35 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
HKD2_k127_5121463_36 Serine hydrolase K07002 - - 0.0000000000000000000000000000000000000000000000000000000000000000002279 236.0
HKD2_k127_5121463_37 Bile acid K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000788 242.0
HKD2_k127_5121463_38 Major Facilitator Superfamily K08167 - - 0.000000000000000000000000000000000000000000000000000000000000000044 231.0
HKD2_k127_5121463_39 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000002035 220.0
HKD2_k127_5121463_4 Probable molybdopterin binding domain K07141 - 2.7.7.76 3.535e-223 707.0
HKD2_k127_5121463_40 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000000000001233 208.0
HKD2_k127_5121463_41 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000009831 211.0
HKD2_k127_5121463_42 XdhC and CoxI family - - - 0.00000000000000000000000000000000000000000000000000000001341 198.0
HKD2_k127_5121463_43 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000001464 204.0
HKD2_k127_5121463_44 oxidation-reduction process K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000002551 201.0
HKD2_k127_5121463_45 Cellulose biosynthesis protein BcsS - - - 0.000000000000000000000000000000000000000000000000000001562 202.0
HKD2_k127_5121463_46 Major Facilitator Superfamily K08167 - - 0.000000000000000000000000000000000000000000000000001756 192.0
HKD2_k127_5121463_47 - - - - 0.00000000000000000000000000000000000003386 147.0
HKD2_k127_5121463_48 Domain of unknown function (DUF1476) - - - 0.0000000000000000000000000000000000001497 143.0
HKD2_k127_5121463_49 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000002607 138.0
HKD2_k127_5121463_5 Branched-chain amino acid transport system / permease component K01998 - - 5.721e-198 626.0
HKD2_k127_5121463_50 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000003663 130.0
HKD2_k127_5121463_51 KTSC domain - - - 0.0000000000000005323 79.0
HKD2_k127_5121463_52 Protein of unknown function, DUF488 - - - 0.00000377 49.0
HKD2_k127_5121463_54 - - - - 0.000009081 50.0
HKD2_k127_5121463_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 557.0
HKD2_k127_5121463_7 SpoU rRNA Methylase family K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 552.0
HKD2_k127_5121463_8 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 539.0
HKD2_k127_5121463_9 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 509.0
HKD2_k127_5154230_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 598.0
HKD2_k127_5154230_1 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 396.0
HKD2_k127_5154230_2 MarR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 340.0
HKD2_k127_5154230_3 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 301.0
HKD2_k127_5184328_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1169.0
HKD2_k127_5184328_1 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 514.0
HKD2_k127_5184328_10 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008315 250.0
HKD2_k127_5184328_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000009026 218.0
HKD2_k127_5184328_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000004389 188.0
HKD2_k127_5184328_13 - - - - 0.00000000000000000000000000000000000000002382 158.0
HKD2_k127_5184328_14 Zinc-finger domain - - - 0.0000000000000000000000000000000001136 135.0
HKD2_k127_5184328_15 - - - - 0.0000000000000000000000000002 124.0
HKD2_k127_5184328_17 Protein of unknown function (DUF2892) - - - 0.0000000000000001153 81.0
HKD2_k127_5184328_18 - - - - 0.0000000000000001407 79.0
HKD2_k127_5184328_19 - - - - 0.00000000001699 72.0
HKD2_k127_5184328_2 Serine acetyltransferase, N-terminal K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 443.0
HKD2_k127_5184328_20 DNA primase - - - 0.0005692 43.0
HKD2_k127_5184328_3 FAD binding domain K00480 - 1.14.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 422.0
HKD2_k127_5184328_4 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 353.0
HKD2_k127_5184328_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 302.0
HKD2_k127_5184328_6 PFAM transglutaminase family protein cysteine peptidase, BTLCP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 291.0
HKD2_k127_5184328_7 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 293.0
HKD2_k127_5184328_8 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005733 269.0
HKD2_k127_5184328_9 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009122 272.0
HKD2_k127_5185757_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 509.0
HKD2_k127_5185757_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 404.0
HKD2_k127_5185757_2 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K15063 - 4.1.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 362.0
HKD2_k127_5185757_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 349.0
HKD2_k127_5185757_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
HKD2_k127_5185757_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000004524 209.0
HKD2_k127_5185757_6 Cupin domain - - - 0.0000000000000000000000000000000002057 134.0
HKD2_k127_5202637_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 1.184e-220 698.0
HKD2_k127_5202637_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 311.0
HKD2_k127_5202637_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000004494 216.0
HKD2_k127_5202637_3 Flavin reductase like domain K09024 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016645,GO:0016646,GO:0042602,GO:0055114 - 0.00000000000000000000000000000000000000000000000149 180.0
HKD2_k127_5204908_0 AMP-binding enzyme C-terminal domain K00666,K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 389.0
HKD2_k127_5204908_1 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001505 244.0
HKD2_k127_5204908_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000001148 124.0
HKD2_k127_5235846_0 ATPase (P-type) K01535 - 3.6.3.6 0.0 1114.0
HKD2_k127_5235846_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000002257 132.0
HKD2_k127_5237793_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.0 1098.0
HKD2_k127_5237793_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.11.2 0.0 1064.0
HKD2_k127_5237793_10 Dimerisation domain of Zinc Transporter K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 450.0
HKD2_k127_5237793_11 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 423.0
HKD2_k127_5237793_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 373.0
HKD2_k127_5237793_13 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 328.0
HKD2_k127_5237793_14 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 329.0
HKD2_k127_5237793_15 COG3243 Poly(3-hydroxyalkanoate) synthetase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 319.0
HKD2_k127_5237793_16 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 312.0
HKD2_k127_5237793_17 surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000002809 221.0
HKD2_k127_5237793_18 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000004471 206.0
HKD2_k127_5237793_19 Phosphopantetheine attachment site - - - 0.00000000000000000000000000000002641 127.0
HKD2_k127_5237793_2 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 1.691e-293 919.0
HKD2_k127_5237793_20 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 0.0000000000000000000000000001262 115.0
HKD2_k127_5237793_3 Histidine kinase - - - 2.263e-199 633.0
HKD2_k127_5237793_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 5.89e-197 623.0
HKD2_k127_5237793_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 6.925e-197 626.0
HKD2_k127_5237793_6 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 558.0
HKD2_k127_5237793_7 Dehydrogenase E1 component K00161,K00166,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 535.0
HKD2_k127_5237793_8 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 505.0
HKD2_k127_5237793_9 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 501.0
HKD2_k127_5246580_0 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 368.0
HKD2_k127_5246580_1 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002339 248.0
HKD2_k127_5246580_2 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000000000000000000000000000000002651 231.0
HKD2_k127_5246797_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 1.864e-263 834.0
HKD2_k127_5246797_1 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 521.0
HKD2_k127_5246797_2 Phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 491.0
HKD2_k127_5246797_3 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001546 270.0
HKD2_k127_5246797_4 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 259.0
HKD2_k127_5246797_5 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000009466 136.0
HKD2_k127_5246797_6 methyl-accepting chemotaxis protein - - - 0.00000000000000000000000003535 111.0
HKD2_k127_5285323_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 996.0
HKD2_k127_5285323_1 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 9.559e-313 964.0
HKD2_k127_5285323_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 439.0
HKD2_k127_5285323_11 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 400.0
HKD2_k127_5285323_12 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 376.0
HKD2_k127_5285323_13 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 355.0
HKD2_k127_5285323_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 344.0
HKD2_k127_5285323_15 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 322.0
HKD2_k127_5285323_16 Peptidase C26 K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 312.0
HKD2_k127_5285323_17 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001611 283.0
HKD2_k127_5285323_18 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007521 270.0
HKD2_k127_5285323_19 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
HKD2_k127_5285323_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 2.737e-255 791.0
HKD2_k127_5285323_20 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000001377 184.0
HKD2_k127_5285323_21 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000003698 138.0
HKD2_k127_5285323_22 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000001089 99.0
HKD2_k127_5285323_23 Competence protein K02238 - - 0.000005885 53.0
HKD2_k127_5285323_24 Competence protein K02238 - - 0.000009839 48.0
HKD2_k127_5285323_25 PFAM Porin K16079 - - 0.00003317 47.0
HKD2_k127_5285323_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 5.195e-247 771.0
HKD2_k127_5285323_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.357e-230 720.0
HKD2_k127_5285323_5 Peptidylprolyl isomerase K01802,K03770 - 5.2.1.8 4.054e-204 653.0
HKD2_k127_5285323_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 516.0
HKD2_k127_5285323_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 510.0
HKD2_k127_5285323_8 MoeA C-terminal region (domain IV) K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 496.0
HKD2_k127_5285323_9 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 440.0
HKD2_k127_5323528_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000004685 227.0
HKD2_k127_5323528_1 Permease family K03458 - - 0.00000000000000000000000000000000000000000000000000000000001878 222.0
HKD2_k127_5344451_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0 1012.0
HKD2_k127_5344451_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.779e-270 840.0
HKD2_k127_5344451_10 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 481.0
HKD2_k127_5344451_11 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 469.0
HKD2_k127_5344451_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 442.0
HKD2_k127_5344451_13 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 422.0
HKD2_k127_5344451_14 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 422.0
HKD2_k127_5344451_15 Phosphomethylpyrimidine kinase K00868 - 2.7.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 394.0
HKD2_k127_5344451_16 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 393.0
HKD2_k127_5344451_17 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 357.0
HKD2_k127_5344451_18 HAD-superfamily hydrolase, subfamily IB K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 347.0
HKD2_k127_5344451_19 PFAM Tripartite ATP-independent periplasmic transporter DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 304.0
HKD2_k127_5344451_2 Tripartite tricarboxylate transporter TctA family K07793 - - 3.077e-252 785.0
HKD2_k127_5344451_20 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 290.0
HKD2_k127_5344451_21 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006474 235.0
HKD2_k127_5344451_22 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000004757 211.0
HKD2_k127_5344451_23 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000004463 220.0
HKD2_k127_5344451_24 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000003706 209.0
HKD2_k127_5344451_25 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000001114 203.0
HKD2_k127_5344451_26 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000000000000000000000000000000171 167.0
HKD2_k127_5344451_27 Lysozyme inhibitor LprI - - - 0.00000000000000000000000000000000000000001383 156.0
HKD2_k127_5344451_28 - - - - 0.0000000000000000000000000000000000007951 150.0
HKD2_k127_5344451_29 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000001917 77.0
HKD2_k127_5344451_3 Tripartite ATP-independent periplasmic transporter, DctM component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 1.07e-221 693.0
HKD2_k127_5344451_31 - - - - 0.0000003822 57.0
HKD2_k127_5344451_4 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 7.099e-215 678.0
HKD2_k127_5344451_5 Sulfatase - - - 2.352e-207 659.0
HKD2_k127_5344451_6 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 1.266e-201 640.0
HKD2_k127_5344451_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 612.0
HKD2_k127_5344451_8 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 576.0
HKD2_k127_5344451_9 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 540.0
HKD2_k127_5351656_0 L,D-transpeptidase catalytic domain - - - 2.683e-230 724.0
HKD2_k127_5351656_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 341.0
HKD2_k127_5351656_2 Transglycosylase associated protein - - - 0.000000000000000000000000001094 115.0
HKD2_k127_5351656_3 Domain of unknown function (DUF3597) - - - 0.0000000000001675 72.0
HKD2_k127_5393237_0 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 416.0
HKD2_k127_5393237_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002694 275.0
HKD2_k127_5393237_2 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000289 229.0
HKD2_k127_5393237_3 Eukaryotic cytochrome b561 - - - 0.000000000000000000001293 104.0
HKD2_k127_5425469_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1764.0
HKD2_k127_5425469_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 471.0
HKD2_k127_5425469_10 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 334.0
HKD2_k127_5425469_11 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 314.0
HKD2_k127_5425469_12 Biotin/lipoate A/B protein ligase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 301.0
HKD2_k127_5425469_13 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000759 276.0
HKD2_k127_5425469_14 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001739 252.0
HKD2_k127_5425469_15 Molybdopterin guanine dinucleotide synthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000009446 224.0
HKD2_k127_5425469_16 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000000000000000000000000000001015 213.0
HKD2_k127_5425469_17 - - - - 0.000000000000000000000000000000000000000000000000000000002093 206.0
HKD2_k127_5425469_18 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000001302 133.0
HKD2_k127_5425469_19 Protein of unknown function (DUF3306) - - - 0.000000000000000000000000000003004 128.0
HKD2_k127_5425469_2 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 483.0
HKD2_k127_5425469_20 - - - - 0.0000000000000000000000000002286 119.0
HKD2_k127_5425469_21 Recombinase zinc beta ribbon domain - - - 0.000000000001102 68.0
HKD2_k127_5425469_22 TIGRFAM formate dehydrogenase region TAT target - - - 0.00000000006109 64.0
HKD2_k127_5425469_23 - - - - 0.000000002025 60.0
HKD2_k127_5425469_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 462.0
HKD2_k127_5425469_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 446.0
HKD2_k127_5425469_5 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 441.0
HKD2_k127_5425469_6 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 417.0
HKD2_k127_5425469_7 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 407.0
HKD2_k127_5425469_8 Belongs to the MenA family. Type 1 subfamily K02548 GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 353.0
HKD2_k127_5425469_9 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 345.0
HKD2_k127_542894_0 ATP-dependent helicase K03579 - 3.6.4.13 1.657e-267 837.0
HKD2_k127_542894_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 282.0
HKD2_k127_5430231_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 414.0
HKD2_k127_5430231_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 348.0
HKD2_k127_5430231_2 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 314.0
HKD2_k127_5430231_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 309.0
HKD2_k127_5430231_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000001937 69.0
HKD2_k127_5477472_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.523e-243 764.0
HKD2_k127_5477472_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 419.0
HKD2_k127_5477472_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 336.0
HKD2_k127_5477472_3 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
HKD2_k127_5477472_4 methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000007659 239.0
HKD2_k127_5477472_5 mandelate racemase muconate lactonizing K22209 - 4.2.1.81 0.000000000000000000000000000000000000000000000000000000001528 207.0
HKD2_k127_5477472_6 Belongs to the mandelate racemase muconate lactonizing enzyme family K22209 - 4.2.1.81 0.000000000000000000000002396 109.0
HKD2_k127_5570345_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.164e-202 635.0
HKD2_k127_5570345_1 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 421.0
HKD2_k127_557294_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 472.0
HKD2_k127_557294_1 DNA polymerase III delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 402.0
HKD2_k127_557294_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 370.0
HKD2_k127_557294_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 335.0
HKD2_k127_557294_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005678 275.0
HKD2_k127_557294_5 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000005552 128.0
HKD2_k127_557294_6 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000003009 107.0
HKD2_k127_557294_7 - - - - 0.0000000000000000007642 90.0
HKD2_k127_5585603_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1165.0
HKD2_k127_5585603_1 Domain of unknown function (DUF3578) - - - 0.0000004489 52.0
HKD2_k127_5585603_2 Belongs to the 'phage' integrase family - - - 0.00001587 49.0
HKD2_k127_568807_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 593.0
HKD2_k127_568807_1 phosphatidylethanolamine N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
HKD2_k127_568807_2 - - - - 0.00000000000000000006287 94.0
HKD2_k127_5882967_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
HKD2_k127_5882967_1 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 352.0
HKD2_k127_5882967_2 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000001836 105.0
HKD2_k127_5882967_3 Erythromycin esterase - - - 0.000000008854 62.0
HKD2_k127_5890357_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 589.0
HKD2_k127_5890357_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 548.0
HKD2_k127_5890357_10 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000005016 267.0
HKD2_k127_5890357_11 Protein of unknown function (DUF1348) K09958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003712 252.0
HKD2_k127_5890357_12 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001998 259.0
HKD2_k127_5890357_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003568 256.0
HKD2_k127_5890357_14 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004747 246.0
HKD2_k127_5890357_15 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000001531 248.0
HKD2_k127_5890357_16 KR domain K00038 - 1.1.1.53 0.00000000000000000000000000000000000000000000000000000000000412 218.0
HKD2_k127_5890357_17 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000005145 226.0
HKD2_k127_5890357_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000001762 203.0
HKD2_k127_5890357_19 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000003235 193.0
HKD2_k127_5890357_2 Carbon-nitrogen hydrolase K01501,K01502 - 3.5.5.1,3.5.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 457.0
HKD2_k127_5890357_20 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000001704 188.0
HKD2_k127_5890357_21 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000009994 188.0
HKD2_k127_5890357_22 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000001114 144.0
HKD2_k127_5890357_23 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000133 141.0
HKD2_k127_5890357_24 Transcriptional regulator K02624 - - 0.000000000000000000000000000001122 125.0
HKD2_k127_5890357_25 transcriptional regulator K02624,K20539 - - 0.000000000000000000196 99.0
HKD2_k127_5890357_26 Endoribonuclease L-PSP - - - 0.000000000000000001209 90.0
HKD2_k127_5890357_27 Cupin domain - - - 0.00000000001609 71.0
HKD2_k127_5890357_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 423.0
HKD2_k127_5890357_4 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 414.0
HKD2_k127_5890357_5 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 342.0
HKD2_k127_5890357_6 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 339.0
HKD2_k127_5890357_7 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 346.0
HKD2_k127_5890357_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
HKD2_k127_5890357_9 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 309.0
HKD2_k127_5983825_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 605.0
HKD2_k127_5983825_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 592.0
HKD2_k127_5983825_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 424.0
HKD2_k127_5983825_11 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 421.0
HKD2_k127_5983825_12 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 425.0
HKD2_k127_5983825_13 Transcriptional regulatory protein, C terminal K07657 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 407.0
HKD2_k127_5983825_14 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 413.0
HKD2_k127_5983825_15 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 403.0
HKD2_k127_5983825_16 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 391.0
HKD2_k127_5983825_17 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
HKD2_k127_5983825_18 belongs to the carbohydrate kinase PfkB family K16370 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 334.0
HKD2_k127_5983825_19 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001862 256.0
HKD2_k127_5983825_2 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 567.0
HKD2_k127_5983825_20 GcrA cell cycle regulator K13583 - - 0.000000000000000000000000000000000000000000000000000000000000000000004716 237.0
HKD2_k127_5983825_21 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000006733 230.0
HKD2_k127_5983825_22 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000001097 230.0
HKD2_k127_5983825_23 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000000002014 193.0
HKD2_k127_5983825_24 N-Acetylmuramoyl-L-alanine amidase K01448 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008745,GO:0016787,GO:0016810,GO:0016811,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0061783 3.5.1.28 0.00000000000000000000000000000000000000000000000008018 185.0
HKD2_k127_5983825_25 sh3 domain protein K01447,K01448,K09774 - 3.5.1.28 0.00000000000000000000733 105.0
HKD2_k127_5983825_26 - - - - 0.000000000000006194 77.0
HKD2_k127_5983825_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 525.0
HKD2_k127_5983825_4 OpgC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 508.0
HKD2_k127_5983825_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 500.0
HKD2_k127_5983825_6 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 493.0
HKD2_k127_5983825_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 483.0
HKD2_k127_5983825_8 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 466.0
HKD2_k127_5983825_9 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 454.0
HKD2_k127_605141_0 ABC transporter K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 1.047e-318 985.0
HKD2_k127_605141_1 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.818e-304 945.0
HKD2_k127_605141_10 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 1.497e-238 742.0
HKD2_k127_605141_11 His Kinase A (phosphoacceptor) domain K07716 - 2.7.13.3 4.303e-229 721.0
HKD2_k127_605141_12 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 1.83e-228 720.0
HKD2_k127_605141_13 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K05712 - 1.14.13.127 1.436e-226 713.0
HKD2_k127_605141_14 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0000302,GO:0000305,GO:0003674,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0017076,GO:0019725,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0045454,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0065008,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901700 1.8.1.7 1.533e-204 645.0
HKD2_k127_605141_15 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 8.937e-198 623.0
HKD2_k127_605141_16 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.259e-196 623.0
HKD2_k127_605141_17 Major Facilitator Superfamily - - - 8.027e-196 617.0
HKD2_k127_605141_18 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 608.0
HKD2_k127_605141_19 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 563.0
HKD2_k127_605141_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.717e-304 939.0
HKD2_k127_605141_20 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 562.0
HKD2_k127_605141_21 synthase K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 556.0
HKD2_k127_605141_22 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 550.0
HKD2_k127_605141_23 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 541.0
HKD2_k127_605141_24 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 522.0
HKD2_k127_605141_25 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 509.0
HKD2_k127_605141_26 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 491.0
HKD2_k127_605141_27 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 481.0
HKD2_k127_605141_28 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 456.0
HKD2_k127_605141_29 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 467.0
HKD2_k127_605141_3 Acyl-CoA reductase (LuxC) K00140 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896 1.2.1.18,1.2.1.27 3.471e-285 880.0
HKD2_k127_605141_30 lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 398.0
HKD2_k127_605141_31 CDP-alcohol phosphatidyltransferase K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 376.0
HKD2_k127_605141_32 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 366.0
HKD2_k127_605141_33 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 332.0
HKD2_k127_605141_34 Protein of unknown function (DUF2865) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 332.0
HKD2_k127_605141_35 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 316.0
HKD2_k127_605141_36 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 309.0
HKD2_k127_605141_37 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
HKD2_k127_605141_38 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 301.0
HKD2_k127_605141_39 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 296.0
HKD2_k127_605141_4 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.854e-284 885.0
HKD2_k127_605141_40 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 293.0
HKD2_k127_605141_41 Shikimate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 291.0
HKD2_k127_605141_42 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005451 282.0
HKD2_k127_605141_43 PFAM Glutathione S-transferase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000007321 262.0
HKD2_k127_605141_44 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001377 257.0
HKD2_k127_605141_45 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000004676 239.0
HKD2_k127_605141_46 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000008266 234.0
HKD2_k127_605141_47 Acetyltransferase (GNAT) domain K03830 - - 0.00000000000000000000000000000000000000000000000000000000000000005033 227.0
HKD2_k127_605141_48 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000235 225.0
HKD2_k127_605141_49 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000004447 205.0
HKD2_k127_605141_5 DNA ligase K01971 - 6.5.1.1 3.415e-280 886.0
HKD2_k127_605141_50 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000001007 198.0
HKD2_k127_605141_51 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000002346 205.0
HKD2_k127_605141_52 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000001256 195.0
HKD2_k127_605141_53 Phosphopantetheine attachment site - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000006961 176.0
HKD2_k127_605141_54 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000962 175.0
HKD2_k127_605141_55 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000000000112 167.0
HKD2_k127_605141_56 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000001519 162.0
HKD2_k127_605141_57 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000005535 153.0
HKD2_k127_605141_58 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000003205 155.0
HKD2_k127_605141_59 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000001723 149.0
HKD2_k127_605141_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.367e-275 854.0
HKD2_k127_605141_60 ferredoxin K04755 - - 0.0000000000000000000000000000000000001064 149.0
HKD2_k127_605141_61 Low affinity iron permease - - - 0.0000000000000000000000000000000000007085 145.0
HKD2_k127_605141_62 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000001202 141.0
HKD2_k127_605141_63 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.000000000000000000000000000000000276 139.0
HKD2_k127_605141_64 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000001383 121.0
HKD2_k127_605141_65 - - - - 0.0000000000000000000000001401 111.0
HKD2_k127_605141_66 Lytic transglycolase K03642 - - 0.00000000000000000000003746 106.0
HKD2_k127_605141_67 - - - - 0.000000000000000000002541 97.0
HKD2_k127_605141_68 - - - - 0.00000000000000000001379 98.0
HKD2_k127_605141_69 - - - - 0.00000000000000000001479 98.0
HKD2_k127_605141_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 2.031e-268 836.0
HKD2_k127_605141_71 Protein of unknown function (DUF1289) K06938 - - 0.00000000000322 69.0
HKD2_k127_605141_72 - - - - 0.0000001373 56.0
HKD2_k127_605141_73 transcriptional Regulator, LysR family K21757 - - 0.000003172 49.0
HKD2_k127_605141_74 Domain of unknown function (DUF1330) - - - 0.00001802 53.0
HKD2_k127_605141_75 MotA/TolQ/ExbB proton channel family K02556 - - 0.00001857 47.0
HKD2_k127_605141_76 Outer membrane lipoprotein omp19 - - - 0.00004279 51.0
HKD2_k127_605141_8 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 2.024e-267 826.0
HKD2_k127_605141_9 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.803e-266 827.0
HKD2_k127_6143097_0 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0 1306.0
HKD2_k127_6143097_1 Protein of unknown function - - - 0.0 1079.0
HKD2_k127_6143097_10 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 549.0
HKD2_k127_6143097_11 4-hydroxybenzoate K00481 - 1.14.13.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 504.0
HKD2_k127_6143097_12 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 501.0
HKD2_k127_6143097_13 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 479.0
HKD2_k127_6143097_14 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 461.0
HKD2_k127_6143097_15 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 398.0
HKD2_k127_6143097_16 Aminotransferase class-V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 401.0
HKD2_k127_6143097_17 ATPases associated with a variety of cellular activities K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 389.0
HKD2_k127_6143097_18 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001268 274.0
HKD2_k127_6143097_19 Diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000001707 276.0
HKD2_k127_6143097_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1073.0
HKD2_k127_6143097_20 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001327 262.0
HKD2_k127_6143097_21 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
HKD2_k127_6143097_22 Belongs to the HesB IscA family K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009058,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0018130,GO:0019438,GO:0019538,GO:0022607,GO:0031163,GO:0031974,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0070013,GO:0071704,GO:0071840,GO:0097428,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000006078 198.0
HKD2_k127_6143097_23 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000008203 178.0
HKD2_k127_6143097_24 methyltransferase activity - - - 0.0000000000000000000000000000000000003823 145.0
HKD2_k127_6143097_25 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000001428 114.0
HKD2_k127_6143097_26 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000002361 95.0
HKD2_k127_6143097_27 Diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000003176 85.0
HKD2_k127_6143097_28 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000006804 55.0
HKD2_k127_6143097_29 - - - - 0.0000003937 58.0
HKD2_k127_6143097_3 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 3.53e-286 883.0
HKD2_k127_6143097_4 Carbamoyltransferase C-terminus - - - 2e-282 884.0
HKD2_k127_6143097_5 Ribonuclease E/G family K08300 - 3.1.26.12 3.053e-246 791.0
HKD2_k127_6143097_6 Cys/Met metabolism PLP-dependent enzyme K11717 - 2.8.1.7,4.4.1.16 4.428e-219 685.0
HKD2_k127_6143097_7 Belongs to the DEAD box helicase family K03732,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 613.0
HKD2_k127_6143097_8 amino acid peptide transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 584.0
HKD2_k127_6143097_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 574.0
HKD2_k127_614351_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 424.0
HKD2_k127_614351_1 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004993 259.0
HKD2_k127_614351_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000002043 228.0
HKD2_k127_614351_3 Polysaccharide biosynthesis protein K13013 - - 0.0000000000000000000000000000000000000000000007632 168.0
HKD2_k127_624494_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1720.0
HKD2_k127_624494_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.094e-227 736.0
HKD2_k127_624494_10 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 309.0
HKD2_k127_624494_11 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002194 260.0
HKD2_k127_624494_12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005291 253.0
HKD2_k127_624494_13 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000008853 248.0
HKD2_k127_624494_14 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000002606 220.0
HKD2_k127_624494_15 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000002629 195.0
HKD2_k127_624494_16 - - - - 0.000000000000000000000000000000002484 138.0
HKD2_k127_624494_17 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000006924 93.0
HKD2_k127_624494_18 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000001065 54.0
HKD2_k127_624494_2 Protein of unknown function (DUF1343) - - - 8.439e-221 689.0
HKD2_k127_624494_20 Integrase - - - 0.0002187 46.0
HKD2_k127_624494_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 559.0
HKD2_k127_624494_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 399.0
HKD2_k127_624494_5 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 385.0
HKD2_k127_624494_6 hydrolases or acyltransferases, alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 381.0
HKD2_k127_624494_7 BadF/BadG/BcrA/BcrD ATPase family K18676 - 2.7.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 346.0
HKD2_k127_624494_8 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 344.0
HKD2_k127_624494_9 PFAM sugar isomerase (SIS) K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 333.0
HKD2_k127_62834_0 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.0 1141.0
HKD2_k127_62834_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 445.0
HKD2_k127_62834_10 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000000000000000000000000000006198 134.0
HKD2_k127_62834_11 Cold shock K03704 - - 0.00000000000000000000000000005308 116.0
HKD2_k127_62834_12 Protein of unknown function (DUF3309) - - - 0.0000000000000000001914 89.0
HKD2_k127_62834_13 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000001708 60.0
HKD2_k127_62834_14 PilZ domain - - - 0.0000000711 58.0
HKD2_k127_62834_15 Diguanylate cyclase - - - 0.00000108 53.0
HKD2_k127_62834_2 GDP-mannose 4,6 dehydratase K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 427.0
HKD2_k127_62834_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 340.0
HKD2_k127_62834_4 Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 319.0
HKD2_k127_62834_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 304.0
HKD2_k127_62834_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 308.0
HKD2_k127_62834_7 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000004465 203.0
HKD2_k127_62834_8 Flagellar biosynthesis protein, FliO - - - 0.000000000000000000000000000000000000000000009337 175.0
HKD2_k127_62834_9 Cupin domain - - - 0.00000000000000000000000000000000000000000002647 166.0
HKD2_k127_6412150_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.183e-300 932.0
HKD2_k127_6412150_1 Thiamine pyrophosphate enzyme, central domain K03336 - 3.7.1.22 5.151e-285 888.0
HKD2_k127_6412150_10 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 411.0
HKD2_k127_6412150_11 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 391.0
HKD2_k127_6412150_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 382.0
HKD2_k127_6412150_13 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K15063 - 4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 369.0
HKD2_k127_6412150_14 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 346.0
HKD2_k127_6412150_15 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 336.0
HKD2_k127_6412150_16 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 316.0
HKD2_k127_6412150_17 Branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 291.0
HKD2_k127_6412150_18 Dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002208 276.0
HKD2_k127_6412150_19 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007809 268.0
HKD2_k127_6412150_2 Alcohol dehydrogenase GroES-like domain - - - 5.809e-205 642.0
HKD2_k127_6412150_20 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002066 262.0
HKD2_k127_6412150_21 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
HKD2_k127_6412150_22 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000003275 218.0
HKD2_k127_6412150_23 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000001219 199.0
HKD2_k127_6412150_24 Thioesterase - - - 0.000000000000000000000000000000000000000000000006954 177.0
HKD2_k127_6412150_25 Cupin domain - - - 0.0000000000000000000000000000000000003396 143.0
HKD2_k127_6412150_26 Methyltransferase - - - 0.000000000000000003994 92.0
HKD2_k127_6412150_27 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000432 70.0
HKD2_k127_6412150_28 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.00000000003637 63.0
HKD2_k127_6412150_3 ABC transporter substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 594.0
HKD2_k127_6412150_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 511.0
HKD2_k127_6412150_5 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 517.0
HKD2_k127_6412150_6 Major facilitator superfamily K03449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 450.0
HKD2_k127_6412150_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 433.0
HKD2_k127_6412150_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 418.0
HKD2_k127_6412150_9 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 409.0
HKD2_k127_6418870_0 ABC transporter K15738 - - 7.501e-316 973.0
HKD2_k127_6418870_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 531.0
HKD2_k127_6418870_11 - - - - 0.000000000001875 70.0
HKD2_k127_6418870_12 membrane protein (DUF2078) K08982 - - 0.000002042 52.0
HKD2_k127_6418870_13 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.00007283 48.0
HKD2_k127_6418870_14 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.0001007 50.0
HKD2_k127_6418870_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 431.0
HKD2_k127_6418870_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005137 259.0
HKD2_k127_6418870_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000004747 195.0
HKD2_k127_6418870_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03574 - 3.6.1.55 0.000000000000000000000000000000000000117 149.0
HKD2_k127_6418870_6 Domain of Unknown Function (DUF930) - - - 0.00000000000000000000000000000007456 128.0
HKD2_k127_6418870_7 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.00000000000000000000000000002003 121.0
HKD2_k127_6418870_8 - - - - 0.00000000000000000000000000256 115.0
HKD2_k127_6418870_9 - - - - 0.000000000000000000000000841 107.0
HKD2_k127_6420248_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 581.0
HKD2_k127_6420248_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 455.0
HKD2_k127_6420248_2 Protein containing von Willebrand factor type A (VWA) domain - - - 0.00000000000000000000000009562 108.0
HKD2_k127_6432333_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1024.0
HKD2_k127_6432333_1 Participates in both transcription termination and antitermination K02600 - - 6.986e-281 869.0
HKD2_k127_6432333_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000005901 248.0
HKD2_k127_6432333_3 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000000000000000000000000000000000000003347 224.0
HKD2_k127_6432333_4 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000001559 205.0
HKD2_k127_6438055_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate K01703 - 4.2.1.33,4.2.1.35 7.432e-226 709.0
HKD2_k127_6438055_1 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000002743 226.0
HKD2_k127_6438055_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000001151 218.0
HKD2_k127_6444421_0 Sulfatase - - - 2.612e-205 653.0
HKD2_k127_6444421_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 419.0
HKD2_k127_6444421_2 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000002224 222.0
HKD2_k127_6444421_3 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000001653 153.0
HKD2_k127_6451711_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 6.146e-224 705.0
HKD2_k127_6451711_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 2.492e-201 634.0
HKD2_k127_6451711_10 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000003509 209.0
HKD2_k127_6451711_11 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000000000000000000000003322 189.0
HKD2_k127_6451711_12 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.00000000000000000000000000000000000000000000000003061 189.0
HKD2_k127_6451711_13 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000003296 145.0
HKD2_k127_6451711_14 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000001782 84.0
HKD2_k127_6451711_15 Helix-turn-helix XRE-family like proteins - - - 0.0000000005058 70.0
HKD2_k127_6451711_2 nucleoside-triphosphate diphosphatase activity K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 368.0
HKD2_k127_6451711_3 Protein of unknown function DUF262 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 334.0
HKD2_k127_6451711_4 Belongs to the UPF0262 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004756 265.0
HKD2_k127_6451711_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
HKD2_k127_6451711_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004103 243.0
HKD2_k127_6451711_7 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005408 235.0
HKD2_k127_6451711_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000009113 231.0
HKD2_k127_6451711_9 Low molecular weight phosphotyrosine protein phosphatase K01104,K03741 - 1.20.4.1,3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000006014 217.0
HKD2_k127_6454076_0 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 421.0
HKD2_k127_6454076_1 NMT1/THI5 like K02051,K15598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 313.0
HKD2_k127_6454076_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 317.0
HKD2_k127_6477842_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 593.0
HKD2_k127_6477842_1 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000006706 191.0
HKD2_k127_6477842_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000001017 64.0
HKD2_k127_6483011_0 Hopanoid biosynthesis associated radical SAM protein HpnH - - - 1.773e-203 638.0
HKD2_k127_6483011_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 454.0
HKD2_k127_6483011_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 440.0
HKD2_k127_6483011_3 Squalene--hopene cyclase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000004929 143.0
HKD2_k127_6483011_4 LTXXQ motif family protein - - - 0.000000000000001728 89.0
HKD2_k127_6483247_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.264e-291 902.0
HKD2_k127_6483247_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 578.0
HKD2_k127_6483247_10 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 319.0
HKD2_k127_6483247_11 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007239 275.0
HKD2_k127_6483247_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000604 251.0
HKD2_k127_6483247_13 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000001323 238.0
HKD2_k127_6483247_14 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002807 237.0
HKD2_k127_6483247_15 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000007434 226.0
HKD2_k127_6483247_16 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000002345 213.0
HKD2_k127_6483247_17 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000008276 198.0
HKD2_k127_6483247_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000001644 176.0
HKD2_k127_6483247_19 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000006082 149.0
HKD2_k127_6483247_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 537.0
HKD2_k127_6483247_20 - - - - 0.00000000000000000000000000000009697 130.0
HKD2_k127_6483247_21 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000002217 119.0
HKD2_k127_6483247_22 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000007559 103.0
HKD2_k127_6483247_23 - - - - 0.0000000000000000007138 89.0
HKD2_k127_6483247_24 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K18336 - - 0.0000000000000000496 87.0
HKD2_k127_6483247_26 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region K14986 - 2.7.13.3 0.0000000000001835 78.0
HKD2_k127_6483247_27 Eukaryotic cytochrome b561 - - - 0.0000000000004755 76.0
HKD2_k127_6483247_28 peptidase inhibitor activity - - - 0.0000000000009678 74.0
HKD2_k127_6483247_29 - - - - 0.00000000008365 74.0
HKD2_k127_6483247_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 517.0
HKD2_k127_6483247_30 acetolactate decarboxylase activity K01575 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0047605 4.1.1.5 0.00000001453 66.0
HKD2_k127_6483247_31 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000009992 56.0
HKD2_k127_6483247_33 - - - - 0.0007936 44.0
HKD2_k127_6483247_34 Terminase RNaseH-like domain - - - 0.0008002 42.0
HKD2_k127_6483247_4 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 387.0
HKD2_k127_6483247_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 365.0
HKD2_k127_6483247_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 358.0
HKD2_k127_6483247_7 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 342.0
HKD2_k127_6483247_8 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
HKD2_k127_6483247_9 ABC-type transport auxiliary lipoprotein component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
HKD2_k127_6484382_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 406.0
HKD2_k127_6484382_1 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 396.0
HKD2_k127_6484382_2 Thymidine phosphorylase K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016757,GO:0016758,GO:0044424,GO:0044444,GO:0044464 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 293.0
HKD2_k127_6496120_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
HKD2_k127_6496120_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000003767 228.0
HKD2_k127_6496120_2 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000001019 201.0
HKD2_k127_6496120_3 NMT1-like family K02051 - - 0.000000000000001227 83.0
HKD2_k127_6497119_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 7.779e-263 872.0
HKD2_k127_6497119_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 433.0
HKD2_k127_6497119_2 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 306.0
HKD2_k127_6497119_3 Phosphorylase superfamily - - - 0.00000000000000000000000000000002017 128.0
HKD2_k127_6497119_4 Thioredoxin domain - - - 0.0000000000000000000004776 100.0
HKD2_k127_6497119_5 Universal stress protein family - - - 0.0000000000000006862 79.0
HKD2_k127_6497119_6 Dehydratase family K01687 - 4.2.1.9 0.000000001015 62.0
HKD2_k127_6497119_7 Calcineurin-like phosphoesterase K06953 - - 0.0003688 44.0
HKD2_k127_6521921_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 1.215e-241 750.0
HKD2_k127_6521921_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 367.0
HKD2_k127_6521921_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 369.0
HKD2_k127_6521921_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 325.0
HKD2_k127_6521921_4 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000000000843 201.0
HKD2_k127_6521921_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000966 201.0
HKD2_k127_6521921_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000003752 143.0
HKD2_k127_6521921_7 Alpha beta hydrolase - - - 0.0000000000000000000000000000000001035 135.0
HKD2_k127_6537145_0 Cytochrome c-type biogenesis protein K02198 - - 1.145e-233 729.0
HKD2_k127_6537145_1 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 520.0
HKD2_k127_6537145_10 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000002018 186.0
HKD2_k127_6537145_11 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000001901 164.0
HKD2_k127_6537145_12 UPF0391 membrane protein - - - 0.00000000000000001076 83.0
HKD2_k127_6537145_13 - - - - 0.0000000003617 63.0
HKD2_k127_6537145_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 383.0
HKD2_k127_6537145_3 HWE histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 379.0
HKD2_k127_6537145_4 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 336.0
HKD2_k127_6537145_5 Kelch repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 307.0
HKD2_k127_6537145_6 myo-inosose-2 dehydratase activity K00457,K06606 - 1.13.11.27,5.3.99.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 295.0
HKD2_k127_6537145_7 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 281.0
HKD2_k127_6537145_8 PFAM Major Facilitator Superfamily K08196,K08369 - - 0.00000000000000000000000000000000000000000000000000000000000003976 231.0
HKD2_k127_6537145_9 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000002521 209.0
HKD2_k127_6549025_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 288.0
HKD2_k127_6549025_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002074 261.0
HKD2_k127_6549025_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000001015 231.0
HKD2_k127_6549025_3 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000000004236 115.0
HKD2_k127_6566627_0 B12 binding domain K14447 - 5.4.99.63 1.361e-303 940.0
HKD2_k127_6566627_1 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000001626 110.0
HKD2_k127_6568999_0 ribosomal rna small subunit methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 577.0
HKD2_k127_6568999_1 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000005665 190.0
HKD2_k127_6568999_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000824 126.0
HKD2_k127_6584513_0 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 307.0
HKD2_k127_6584513_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002978 277.0
HKD2_k127_6584513_2 COG0410 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 270.0
HKD2_k127_6598594_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 8.043e-286 880.0
HKD2_k127_6598594_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 2.505e-257 796.0
HKD2_k127_6598594_10 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 298.0
HKD2_k127_6598594_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001942 273.0
HKD2_k127_6598594_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 271.0
HKD2_k127_6598594_13 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003937 261.0
HKD2_k127_6598594_14 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000468 246.0
HKD2_k127_6598594_15 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000003525 233.0
HKD2_k127_6598594_16 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000005775 220.0
HKD2_k127_6598594_17 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
HKD2_k127_6598594_18 - - - - 0.0000000000000000000000000000000000000000000000007497 178.0
HKD2_k127_6598594_19 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000106 172.0
HKD2_k127_6598594_2 Cys/Met metabolism PLP-dependent enzyme K01738,K01740 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003961,GO:0004124,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0050667,GO:0071265,GO:0071266,GO:0071268,GO:0071269,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47,2.5.1.49 2.169e-239 745.0
HKD2_k127_6598594_20 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000971 108.0
HKD2_k127_6598594_21 Protein of unknown function (DUF2842) - - - 0.0000000000000000004349 89.0
HKD2_k127_6598594_22 - - - - 0.00000004437 63.0
HKD2_k127_6598594_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 603.0
HKD2_k127_6598594_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 590.0
HKD2_k127_6598594_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 586.0
HKD2_k127_6598594_6 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 390.0
HKD2_k127_6598594_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 379.0
HKD2_k127_6598594_8 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 374.0
HKD2_k127_6598594_9 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 345.0
HKD2_k127_6623873_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 370.0
HKD2_k127_6623873_1 - - - - 0.00000000000000000000000000000000000000000000000002198 187.0
HKD2_k127_6623873_2 Fumarylacetoacetate (FAA) hydrolase family K01826 - 5.3.3.10 0.000000000000000000000000000000000000000000002136 175.0
HKD2_k127_6623873_3 glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.000000000000000000000000000000002703 132.0
HKD2_k127_6623873_4 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.00000000000000000000005589 111.0
HKD2_k127_6641694_0 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 485.0
HKD2_k127_6641694_1 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 458.0
HKD2_k127_6641694_2 Transport permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 413.0
HKD2_k127_6641694_3 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000203 283.0
HKD2_k127_6641694_4 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000004601 247.0
HKD2_k127_6641694_5 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000000000001625 199.0
HKD2_k127_6641694_6 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000009106 173.0
HKD2_k127_6641694_7 Haem-degrading - - - 0.00000000000000000000000000000001368 137.0
HKD2_k127_6653397_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0 1268.0
HKD2_k127_6653397_1 Thiamine pyrophosphate enzyme, central domain - - - 4.577e-292 912.0
HKD2_k127_6653397_10 ABC transporter transmembrane region 2 K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 391.0
HKD2_k127_6653397_11 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 379.0
HKD2_k127_6653397_12 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 360.0
HKD2_k127_6653397_13 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 353.0
HKD2_k127_6653397_14 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000001605 256.0
HKD2_k127_6653397_15 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000000000000000000000000000001119 215.0
HKD2_k127_6653397_16 Cupin - - - 0.000000000000000000000000000000000000000000000000000000004127 200.0
HKD2_k127_6653397_17 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000005984 196.0
HKD2_k127_6653397_18 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000008542 168.0
HKD2_k127_6653397_19 PRC-barrel domain - - - 0.00000000000000000000000000000000000000000001158 166.0
HKD2_k127_6653397_2 Tripartite tricarboxylate transporter TctA family - - - 9.719e-268 835.0
HKD2_k127_6653397_20 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000000000000000000001436 172.0
HKD2_k127_6653397_21 Universal stress protein family - - - 0.000000000000000000000000000000008033 132.0
HKD2_k127_6653397_22 Glycosyltransferase - - - 0.0000000000000000000000000007125 117.0
HKD2_k127_6653397_23 COG0463, glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000001347 101.0
HKD2_k127_6653397_24 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000001013 101.0
HKD2_k127_6653397_25 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K22209 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046872,GO:0047808,GO:0051259,GO:0051260,GO:0065003,GO:0071840 4.2.1.81 0.00000000000000002034 85.0
HKD2_k127_6653397_26 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000007069 87.0
HKD2_k127_6653397_27 - - - - 0.000000001377 66.0
HKD2_k127_6653397_28 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000009288 53.0
HKD2_k127_6653397_3 FAD dependent oxidoreductase - - - 5.824e-247 772.0
HKD2_k127_6653397_4 Periplasmic binding protein K01999 - - 6.417e-225 703.0
HKD2_k127_6653397_5 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05350 - 3.2.1.21 1.467e-204 647.0
HKD2_k127_6653397_6 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 3.214e-204 642.0
HKD2_k127_6653397_7 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 612.0
HKD2_k127_6653397_8 Beta-agarase K01219 - 3.2.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 540.0
HKD2_k127_6653397_9 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000747 467.0
HKD2_k127_6654900_0 Oligopeptidase F K08602 - - 1.995e-302 937.0
HKD2_k127_6654900_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 4.789e-247 770.0
HKD2_k127_6654900_10 Bacterial aa3 type cytochrome c oxidase subunit IV - - - 0.000000002269 63.0
HKD2_k127_6654900_2 Sigma-54 interaction domain K10912 GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 2.755e-222 701.0
HKD2_k127_6654900_3 ABC1 family - - - 1.629e-214 674.0
HKD2_k127_6654900_4 Alanine dehydrogenase/PNT, C-terminal domain K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 589.0
HKD2_k127_6654900_5 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 353.0
HKD2_k127_6654900_6 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 325.0
HKD2_k127_6654900_7 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000009347 227.0
HKD2_k127_6654900_8 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.0000000000000000000000000000000000000000000000015 183.0
HKD2_k127_6654900_9 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000001128 152.0
HKD2_k127_6665995_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1692.0
HKD2_k127_6665995_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1428.0
HKD2_k127_6665995_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K09565 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001877 279.0
HKD2_k127_6665995_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003766 259.0
HKD2_k127_6665995_12 Ankyrin repeats (3 copies) K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007719 254.0
HKD2_k127_6665995_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008234 259.0
HKD2_k127_6665995_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000004187 244.0
HKD2_k127_6665995_15 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004598 244.0
HKD2_k127_6665995_16 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000000000000000000000001224 155.0
HKD2_k127_6665995_17 - - - - 0.0000000000000000000000006156 107.0
HKD2_k127_6665995_18 - - - - 0.0000000000401 68.0
HKD2_k127_6665995_19 - - - - 0.000000001211 60.0
HKD2_k127_6665995_2 Belongs to the UbiD family K03182 - 4.1.1.98 4.761e-284 881.0
HKD2_k127_6665995_20 Outer membrane protein beta-barrel domain K16079 - - 0.000001894 53.0
HKD2_k127_6665995_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 544.0
HKD2_k127_6665995_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 525.0
HKD2_k127_6665995_5 salicylate hydroxylase K00480,K22270 - 1.14.13.1,1.14.13.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 480.0
HKD2_k127_6665995_6 Amidohydrolase K10221 - 3.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 430.0
HKD2_k127_6665995_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 345.0
HKD2_k127_6665995_8 Outer membrane protein beta-barrel domain K16079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 339.0
HKD2_k127_6665995_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 318.0
HKD2_k127_6713262_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.206e-266 827.0
HKD2_k127_6713262_1 Sigma-54 interaction domain K13599 - - 6.927e-244 762.0
HKD2_k127_6713262_10 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0009399,GO:0071941,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000003646 161.0
HKD2_k127_6713262_11 - - - - 0.000000000000000000000246 101.0
HKD2_k127_6713262_2 Sugar (and other) transporter K08172 - - 3.935e-200 632.0
HKD2_k127_6713262_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 598.0
HKD2_k127_6713262_4 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 392.0
HKD2_k127_6713262_5 Hydrolase, TatD family K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 386.0
HKD2_k127_6713262_6 Amino-transferase class IV K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 383.0
HKD2_k127_6713262_7 Phosphoribosyl-ATP pyrophosphohydrolase K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 381.0
HKD2_k127_6713262_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009154 278.0
HKD2_k127_6713262_9 Dehydrogenase K00038 - 1.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000002683 256.0
HKD2_k127_6738783_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1710.0
HKD2_k127_6738783_1 Glycosyl transferase family 21 K00694,K01210 - 2.4.1.12,3.2.1.58 0.0 1272.0
HKD2_k127_6738783_10 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 312.0
HKD2_k127_6738783_11 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 309.0
HKD2_k127_6738783_12 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 290.0
HKD2_k127_6738783_13 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 303.0
HKD2_k127_6738783_14 Invasion associated locus B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001112 259.0
HKD2_k127_6738783_15 - - - - 0.000000000000000000000000000000000000000000000000000333 190.0
HKD2_k127_6738783_16 Hemimethylated DNA-binding protein YccV like K11940 - - 0.0000000000000000000000000000000000000000000000002118 180.0
HKD2_k127_6738783_17 GGDEF domain - - - 0.000000000000000000000000000000000000000000000007283 179.0
HKD2_k127_6738783_18 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000000000004014 119.0
HKD2_k127_6738783_19 GGDEF domain - - - 0.000000000000000000000146 111.0
HKD2_k127_6738783_2 RecG wedge domain K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 4.172e-312 970.0
HKD2_k127_6738783_20 - - - - 0.000000000000001657 81.0
HKD2_k127_6738783_21 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000007069 66.0
HKD2_k127_6738783_22 Tfp pilus assembly protein FimV - - - 0.0000000002008 73.0
HKD2_k127_6738783_23 GGDEF domain - - - 0.0006324 48.0
HKD2_k127_6738783_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.367e-299 928.0
HKD2_k127_6738783_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.435e-252 796.0
HKD2_k127_6738783_5 HpcH/HpaI aldolase/citrate lyase family K08691 GO:0003674,GO:0003824,GO:0005488,GO:0016829,GO:0016830,GO:0016833,GO:0043167,GO:0043169,GO:0046872,GO:0047777,GO:0050083 4.1.3.24,4.1.3.25 5.871e-196 616.0
HKD2_k127_6738783_6 beta (1-6) glucans synthase K01210 - 3.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 580.0
HKD2_k127_6738783_7 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 569.0
HKD2_k127_6738783_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 563.0
HKD2_k127_6738783_9 Alcohol dehydrogenase GroES-like domain K00055 - 1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 396.0
HKD2_k127_6760788_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 7.644e-274 861.0
HKD2_k127_6760788_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.928e-227 709.0
HKD2_k127_6760788_10 Domain of unknown function (DUF4118) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 378.0
HKD2_k127_6760788_11 Protein of unknown function (DUF3500) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 367.0
HKD2_k127_6760788_12 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 291.0
HKD2_k127_6760788_13 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 289.0
HKD2_k127_6760788_14 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000002368 258.0
HKD2_k127_6760788_15 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000003268 257.0
HKD2_k127_6760788_16 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001778 247.0
HKD2_k127_6760788_17 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001121 249.0
HKD2_k127_6760788_18 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001327 238.0
HKD2_k127_6760788_19 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001559 232.0
HKD2_k127_6760788_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 5.24e-198 628.0
HKD2_k127_6760788_20 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000002745 231.0
HKD2_k127_6760788_21 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000005543 227.0
HKD2_k127_6760788_22 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000001212 212.0
HKD2_k127_6760788_23 - - - - 0.000000000000000000000000000000000000000000000000000005217 196.0
HKD2_k127_6760788_24 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000766 197.0
HKD2_k127_6760788_25 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.0000000000000000000000000000000000000000000000000002667 189.0
HKD2_k127_6760788_26 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000006841 193.0
HKD2_k127_6760788_27 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000005551 185.0
HKD2_k127_6760788_28 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000000000002636 170.0
HKD2_k127_6760788_29 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000005048 143.0
HKD2_k127_6760788_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 577.0
HKD2_k127_6760788_30 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000058 134.0
HKD2_k127_6760788_31 PAS fold - - - 0.000000000000000000000005895 104.0
HKD2_k127_6760788_32 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000002221 89.0
HKD2_k127_6760788_33 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.00000005258 60.0
HKD2_k127_6760788_34 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000001168 59.0
HKD2_k127_6760788_4 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 533.0
HKD2_k127_6760788_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 524.0
HKD2_k127_6760788_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 528.0
HKD2_k127_6760788_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 400.0
HKD2_k127_6760788_8 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 385.0
HKD2_k127_6760788_9 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 377.0
HKD2_k127_6776445_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.42e-222 700.0
HKD2_k127_6776445_1 His Kinase A (phosphoacceptor) domain - - - 2.76e-206 674.0
HKD2_k127_6776445_10 PFAM Phasin 2 family protein - - - 0.00000000000000000000000321 106.0
HKD2_k127_6776445_11 - - - - 0.00000000000000001368 86.0
HKD2_k127_6776445_2 AsmA-like C-terminal region K07289 - - 2.361e-201 646.0
HKD2_k127_6776445_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 535.0
HKD2_k127_6776445_4 Binding-protein-dependent transport system inner membrane component K11075 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 429.0
HKD2_k127_6776445_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 424.0
HKD2_k127_6776445_6 Binding-protein-dependent transport system inner membrane component K11074 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 389.0
HKD2_k127_6776445_7 Peptidase C26 K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 359.0
HKD2_k127_6776445_8 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002184 289.0
HKD2_k127_6776445_9 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 278.0
HKD2_k127_6914331_0 Adenylate cyclase - - - 2.456e-241 755.0
HKD2_k127_6914331_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 419.0
HKD2_k127_6914331_2 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 343.0
HKD2_k127_6914331_3 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000002401 80.0
HKD2_k127_6914331_4 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000000002048 74.0
HKD2_k127_6914331_5 Protein of unknown function (DUF3618) - - - 0.0001602 53.0
HKD2_k127_6922953_0 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1377.0
HKD2_k127_6922953_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1244.0
HKD2_k127_6922953_10 Aminotransferase K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 1.727e-229 716.0
HKD2_k127_6922953_11 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 2.03e-227 711.0
HKD2_k127_6922953_12 homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 612.0
HKD2_k127_6922953_13 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 580.0
HKD2_k127_6922953_14 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 569.0
HKD2_k127_6922953_15 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 560.0
HKD2_k127_6922953_16 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 551.0
HKD2_k127_6922953_17 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446,K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009888 534.0
HKD2_k127_6922953_18 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 537.0
HKD2_k127_6922953_19 Response regulator receiver K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 514.0
HKD2_k127_6922953_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0 1009.0
HKD2_k127_6922953_20 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 490.0
HKD2_k127_6922953_21 C4-dicarboxylate transporter malic acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 471.0
HKD2_k127_6922953_22 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 451.0
HKD2_k127_6922953_23 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 462.0
HKD2_k127_6922953_24 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 451.0
HKD2_k127_6922953_25 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 428.0
HKD2_k127_6922953_26 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 415.0
HKD2_k127_6922953_27 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 411.0
HKD2_k127_6922953_28 TIGRFAM lytic murein transglycosylase K00786,K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 392.0
HKD2_k127_6922953_29 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 377.0
HKD2_k127_6922953_3 Carboxyl transferase domain K01969 - 6.4.1.4 4.633e-285 883.0
HKD2_k127_6922953_30 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 369.0
HKD2_k127_6922953_31 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 330.0
HKD2_k127_6922953_32 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 331.0
HKD2_k127_6922953_33 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 308.0
HKD2_k127_6922953_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 307.0
HKD2_k127_6922953_35 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
HKD2_k127_6922953_36 Domain of unknown function (DUF1849) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 296.0
HKD2_k127_6922953_37 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000388 281.0
HKD2_k127_6922953_38 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002829 277.0
HKD2_k127_6922953_39 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001038 272.0
HKD2_k127_6922953_4 DHH family K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 1.883e-271 846.0
HKD2_k127_6922953_40 PFAM heat shock protein DnaJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 273.0
HKD2_k127_6922953_41 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003512 277.0
HKD2_k127_6922953_42 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000006131 259.0
HKD2_k127_6922953_43 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
HKD2_k127_6922953_44 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001864 245.0
HKD2_k127_6922953_45 response regulator K11443 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007052 242.0
HKD2_k127_6922953_46 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005317 244.0
HKD2_k127_6922953_47 PFAM AzlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 240.0
HKD2_k127_6922953_48 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001379 230.0
HKD2_k127_6922953_49 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000000000000000000000001944 227.0
HKD2_k127_6922953_5 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 8.733e-269 839.0
HKD2_k127_6922953_50 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000000000000000001478 220.0
HKD2_k127_6922953_51 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000002667 220.0
HKD2_k127_6922953_52 Protein of unknown function (DUF1489) - - - 0.000000000000000000000000000000000000000000000000000000000009354 210.0
HKD2_k127_6922953_53 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000006358 212.0
HKD2_k127_6922953_54 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000000000000002366 207.0
HKD2_k127_6922953_55 MAPEG family - - - 0.0000000000000000000000000000000000000000000000000000002166 197.0
HKD2_k127_6922953_56 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000202 188.0
HKD2_k127_6922953_57 - K09004 - - 0.000000000000000000000000000000000000000000000002303 177.0
HKD2_k127_6922953_58 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000362 162.0
HKD2_k127_6922953_59 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000000000000000000000000000000000156 162.0
HKD2_k127_6922953_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.492e-266 826.0
HKD2_k127_6922953_60 Phasin protein - - - 0.000000000000000000000000000000000000000008776 156.0
HKD2_k127_6922953_61 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000000000001917 141.0
HKD2_k127_6922953_62 Transcriptional K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000007626 133.0
HKD2_k127_6922953_63 - - - - 0.0000000000000000000000000000002002 135.0
HKD2_k127_6922953_64 GYD domain - - - 0.0000000000000000000000000000007299 124.0
HKD2_k127_6922953_65 - - - - 0.000000000000000000000000000001296 128.0
HKD2_k127_6922953_66 Protein of unknown function (DUF1236) - - - 0.000000000000000000000000000007217 130.0
HKD2_k127_6922953_67 Pfam:UPF0118 - - - 0.00000000000000000000000000005466 117.0
HKD2_k127_6922953_68 Branched-chain amino acid transport - - - 0.0000000000000000000000000003147 118.0
HKD2_k127_6922953_69 Major facilitator Superfamily - - - 0.00000000000000000000000000355 123.0
HKD2_k127_6922953_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.086e-256 798.0
HKD2_k127_6922953_70 Major facilitator Superfamily - - - 0.000000000000000000000009618 102.0
HKD2_k127_6922953_71 Haem-degrading - - - 0.0000000000000000000002363 101.0
HKD2_k127_6922953_72 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000505 87.0
HKD2_k127_6922953_73 - - - - 0.000000000000000002779 90.0
HKD2_k127_6922953_75 Protein of unknown function (DUF3572) - - - 0.000000000000001358 83.0
HKD2_k127_6922953_76 Metallo-beta-lactamase superfamily - - - 0.000000000009996 70.0
HKD2_k127_6922953_77 - - - - 0.00000000001369 66.0
HKD2_k127_6922953_78 Belongs to the UPF0337 (CsbD) family - - - 0.00000000004365 66.0
HKD2_k127_6922953_8 Carbamoyl-phosphate synthase L chain K01968 - 6.4.1.4 1.664e-247 785.0
HKD2_k127_6922953_81 Protein of unknown function (DUF2892) - - - 0.00000001854 57.0
HKD2_k127_6922953_82 - - - - 0.00000004294 59.0
HKD2_k127_6922953_83 Protein of unknown function, DUF599 - - - 0.000000341 55.0
HKD2_k127_6922953_9 acyl-CoA dehydrogenase K09456 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003995,GO:0005488,GO:0005515,GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008470,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016491,GO:0016627,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0033554,GO:0042802,GO:0043565,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 6.087e-235 741.0
HKD2_k127_6958797_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 531.0
HKD2_k127_6958797_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 519.0
HKD2_k127_6958797_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 480.0
HKD2_k127_6958797_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 408.0
HKD2_k127_6991990_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 9.699e-312 973.0
HKD2_k127_6991990_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.458e-283 886.0
HKD2_k127_6991990_10 Leucyl/phenylalanyl-tRNA protein transferase K00684 - 2.3.2.6 0.000000000000000000000003662 107.0
HKD2_k127_6991990_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 8.346e-253 787.0
HKD2_k127_6991990_3 Major Facilitator Superfamily - - - 1.678e-195 620.0
HKD2_k127_6991990_4 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 559.0
HKD2_k127_6991990_5 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 433.0
HKD2_k127_6991990_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 398.0
HKD2_k127_6991990_7 FtsJ-like methyltransferase K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 300.0
HKD2_k127_6991990_8 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000004976 240.0
HKD2_k127_6991990_9 MAPEG family - - - 0.000000000000000000000000000000003044 132.0
HKD2_k127_7019796_0 YcjX-like family, DUF463 K06918 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 318.0
HKD2_k127_7019796_1 Inner membrane component domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006595 227.0
HKD2_k127_7019796_2 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000000000000000000000000007028 208.0
HKD2_k127_7019796_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000003111 200.0
HKD2_k127_7019796_4 MarR family - - - 0.000000000000000000000000000000000000000000000000000005074 194.0
HKD2_k127_7019796_5 Transglycosylase associated protein - - - 0.000000000000000000000000000000000000002258 149.0
HKD2_k127_7019796_6 UPF0283 membrane protein K08990 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000004636 96.0
HKD2_k127_7019796_7 - - - - 0.00000002786 55.0
HKD2_k127_7019796_8 Integrase - - - 0.0003244 48.0
HKD2_k127_7020981_0 Histidinol dehydrogenase - - - 4.631e-220 690.0
HKD2_k127_7020981_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 597.0
HKD2_k127_7020981_10 - - - - 0.000000000000000000003429 98.0
HKD2_k127_7020981_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 397.0
HKD2_k127_7020981_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046,K00065 - 1.1.1.127,1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 364.0
HKD2_k127_7020981_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 342.0
HKD2_k127_7020981_5 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
HKD2_k127_7020981_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 304.0
HKD2_k127_7020981_7 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004677 269.0
HKD2_k127_7020981_8 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000001681 175.0
HKD2_k127_7020981_9 - - - - 0.000000000000000000000005183 108.0
HKD2_k127_7102638_0 AMP-binding enzyme K12508 - 6.2.1.34 7.046e-223 707.0
HKD2_k127_7102638_1 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 434.0
HKD2_k127_7102638_2 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 354.0
HKD2_k127_7102638_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 347.0
HKD2_k127_7102638_4 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000000000000000000172 169.0
HKD2_k127_7102638_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000654 62.0
HKD2_k127_7129439_0 Glutamate synthase K00265 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 0.0 2541.0
HKD2_k127_7129439_1 NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 3.302e-250 779.0
HKD2_k127_7129439_2 Transglycosylase SLT domain K00786,K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 583.0
HKD2_k127_7129439_3 Protein of unknown function (DUF459) K09795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 380.0
HKD2_k127_7129439_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000007204 189.0
HKD2_k127_7176213_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 549.0
HKD2_k127_7176213_1 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 0.0000000000000000000000000000000003568 132.0
HKD2_k127_7181594_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1287.0
HKD2_k127_7181594_1 B12 binding domain K14447 - 5.4.99.63 1e-323 1009.0
HKD2_k127_7181594_10 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 437.0
HKD2_k127_7181594_11 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 435.0
HKD2_k127_7181594_12 ABC-type Fe3 transport system, periplasmic K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 437.0
HKD2_k127_7181594_13 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 432.0
HKD2_k127_7181594_14 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 380.0
HKD2_k127_7181594_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 372.0
HKD2_k127_7181594_16 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 355.0
HKD2_k127_7181594_17 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009136 345.0
HKD2_k127_7181594_18 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 329.0
HKD2_k127_7181594_19 DedA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 303.0
HKD2_k127_7181594_2 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 1.154e-283 887.0
HKD2_k127_7181594_20 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000005959 264.0
HKD2_k127_7181594_21 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002852 256.0
HKD2_k127_7181594_22 Disulfide bond formation protein DsbB K03611 - - 0.000000000000000000000000000000000000000000000000000000002811 204.0
HKD2_k127_7181594_23 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000001011 165.0
HKD2_k127_7181594_24 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000001554 157.0
HKD2_k127_7181594_25 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000001785 158.0
HKD2_k127_7181594_26 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000009614 109.0
HKD2_k127_7181594_27 - - - - 0.00000000000000000003008 98.0
HKD2_k127_7181594_28 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000139 90.0
HKD2_k127_7181594_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 4.304e-258 809.0
HKD2_k127_7181594_4 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 3.111e-227 718.0
HKD2_k127_7181594_5 homoserine dehydrogenase K00003 - 1.1.1.3 1.983e-220 691.0
HKD2_k127_7181594_6 Belongs to the thiolase family K00626 - 2.3.1.9 5.188e-202 634.0
HKD2_k127_7181594_7 FAD binding domain K20940 - 1.14.13.218 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 593.0
HKD2_k127_7181594_8 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 475.0
HKD2_k127_7181594_9 HlyD family secretion protein K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 465.0
HKD2_k127_724874_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1331.0
HKD2_k127_724874_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 469.0
HKD2_k127_724874_2 4Fe-4S binding domain K18362 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 329.0
HKD2_k127_724874_3 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000000000000000000000000004518 198.0
HKD2_k127_7329339_0 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 329.0
HKD2_k127_7329339_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 320.0
HKD2_k127_7329339_10 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000003802 106.0
HKD2_k127_7329339_11 Ribbon-helix-helix domain - - - 0.0000000000000000000000344 102.0
HKD2_k127_7329339_12 - - - - 0.00000000000000005488 84.0
HKD2_k127_7329339_13 Superinfection immunity protein - - - 0.0000000007375 66.0
HKD2_k127_7329339_15 - - - - 0.0000007376 54.0
HKD2_k127_7329339_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006161 261.0
HKD2_k127_7329339_3 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004638 250.0
HKD2_k127_7329339_4 Tryptophan-rich sensory protein K05770 - - 0.000000000000000000000000000000000000000000000000000000001743 203.0
HKD2_k127_7329339_5 - - - - 0.0000000000000000000000000000000000000000000000000562 185.0
HKD2_k127_7329339_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000002357 141.0
HKD2_k127_7329339_7 Ribonuclease B OB domain K03704 - - 0.00000000000000000000000000000005502 125.0
HKD2_k127_7329339_8 Cold shock protein domain K03704 - - 0.00000000000000000000000001256 111.0
HKD2_k127_7329339_9 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000002375 111.0
HKD2_k127_7333926_0 AAA domain, putative AbiEii toxin, Type IV TA system K02074,K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 385.0
HKD2_k127_7333926_1 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 385.0
HKD2_k127_7333926_2 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001164 265.0
HKD2_k127_7333926_3 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000002752 209.0
HKD2_k127_7333926_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000008248 134.0
HKD2_k127_7333926_5 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.0004082 44.0
HKD2_k127_7396396_0 Transglycosylase SLT domain K08309 - - 1.195e-223 716.0
HKD2_k127_7396396_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 503.0
HKD2_k127_7396396_10 - - - - 0.00000000000000003173 86.0
HKD2_k127_7396396_11 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. - - - 0.000000000002821 73.0
HKD2_k127_7396396_12 Alpha/beta hydrolase family K06889 - - 0.000000655 53.0
HKD2_k127_7396396_14 - - - - 0.00006763 47.0
HKD2_k127_7396396_2 Belongs to the sirtuin family. Class K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 393.0
HKD2_k127_7396396_3 Cold shock protein domain K03704 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 338.0
HKD2_k127_7396396_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 325.0
HKD2_k127_7396396_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002514 241.0
HKD2_k127_7396396_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000003081 234.0
HKD2_k127_7396396_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000001353 194.0
HKD2_k127_7396396_8 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000001499 192.0
HKD2_k127_7396396_9 - - - - 0.00000000000000000002414 94.0
HKD2_k127_7508683_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 8.4e-323 1013.0
HKD2_k127_7508683_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 446.0
HKD2_k127_7607725_0 Major Facilitator K03288,K03762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 475.0
HKD2_k127_7607725_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 427.0
HKD2_k127_7607725_10 CHASE4 domain - - - 0.000000004699 59.0
HKD2_k127_7607725_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 359.0
HKD2_k127_7607725_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005993 271.0
HKD2_k127_7607725_4 CHASE - - - 0.000000000000000000000000000000000000000000000000001694 195.0
HKD2_k127_7607725_5 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000002656 179.0
HKD2_k127_7607725_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000002054 148.0
HKD2_k127_7607725_7 Diguanylate cyclase - - - 0.000000000000000000001007 106.0
HKD2_k127_7607725_8 - - - - 0.0000000000001428 77.0
HKD2_k127_7607725_9 Histidine kinase - - - 0.00000000002564 69.0
HKD2_k127_7622294_0 Proton-conducting membrane transporter - - - 1.476e-318 986.0
HKD2_k127_7622294_1 Proton-conducting membrane transporter K12141 - - 9.48e-257 797.0
HKD2_k127_7622294_10 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 360.0
HKD2_k127_7622294_11 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 295.0
HKD2_k127_7622294_12 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004824 278.0
HKD2_k127_7622294_13 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006064 249.0
HKD2_k127_7622294_14 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000002879 239.0
HKD2_k127_7622294_15 Flagellar FliJ protein - - - 0.000000000000000000000000000000000000000000000000000006318 192.0
HKD2_k127_7622294_16 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000001235 190.0
HKD2_k127_7622294_17 Protein of unknown function (DUF1153) - - - 0.00000000000000000000000000000000000000000000000003377 179.0
HKD2_k127_7622294_18 Flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000000000001028 160.0
HKD2_k127_7622294_19 Protein of unknown function (DUF952) - - - 0.0000000000000000000000000000000000006706 149.0
HKD2_k127_7622294_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 2.62e-236 739.0
HKD2_k127_7622294_20 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000008188 135.0
HKD2_k127_7622294_21 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000006455 129.0
HKD2_k127_7622294_22 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.0000000000000000000000006832 105.0
HKD2_k127_7622294_23 Type III flagellar switch regulator (C-ring) FliN C-term K02417 GO:0005575,GO:0005623,GO:0005886,GO:0009288,GO:0009425,GO:0016020,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0071944 - 0.0000000000000000000001334 100.0
HKD2_k127_7622294_24 Flagellar hook-length control protein FliK K10565 - - 0.000000000000000000002015 96.0
HKD2_k127_7622294_25 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000001269 94.0
HKD2_k127_7622294_26 - - - - 0.0000000009256 63.0
HKD2_k127_7622294_27 Protein of unknown function (DUF805) - - - 0.0000000533 54.0
HKD2_k127_7622294_28 Transcriptional regulator - - - 0.0002962 43.0
HKD2_k127_7622294_3 Sigma-54 interaction domain K10943 - - 3.22e-233 727.0
HKD2_k127_7622294_4 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 497.0
HKD2_k127_7622294_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K13584 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 451.0
HKD2_k127_7622294_6 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 439.0
HKD2_k127_7622294_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 422.0
HKD2_k127_7622294_8 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 410.0
HKD2_k127_7622294_9 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 364.0
HKD2_k127_7662223_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 514.0
HKD2_k127_7662223_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 359.0
HKD2_k127_7662223_2 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 340.0
HKD2_k127_7662223_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001946 261.0
HKD2_k127_7662223_4 YCII-related domain K09780 - - 0.0000000000000000000000000000004637 125.0
HKD2_k127_7662223_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000004099 98.0
HKD2_k127_7662223_6 belongs to the aldehyde dehydrogenase family K00141,K21802 - 1.2.1.28,1.2.1.67 0.000000000000000003072 87.0
HKD2_k127_7662223_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000002391 78.0
HKD2_k127_7662223_8 Aldehyde dehydrogenase family K00141 - 1.2.1.28 0.000000000000318 73.0
HKD2_k127_7678539_0 Pfam:NRPS K16395 - - 0.0 1237.0
HKD2_k127_7678539_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6e-323 1000.0
HKD2_k127_7678539_10 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 538.0
HKD2_k127_7678539_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 - 2.1.1.190,2.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 526.0
HKD2_k127_7678539_12 Glycosyltransferase Family 4 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 517.0
HKD2_k127_7678539_13 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 510.0
HKD2_k127_7678539_14 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 510.0
HKD2_k127_7678539_15 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 479.0
HKD2_k127_7678539_16 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 456.0
HKD2_k127_7678539_17 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 454.0
HKD2_k127_7678539_18 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 446.0
HKD2_k127_7678539_19 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 444.0
HKD2_k127_7678539_2 Adenylate and Guanylate cyclase catalytic domain - - - 6.606e-321 1016.0
HKD2_k127_7678539_20 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 426.0
HKD2_k127_7678539_21 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 426.0
HKD2_k127_7678539_22 Short-chain dehydrogenase reductase SDR K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 406.0
HKD2_k127_7678539_23 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 403.0
HKD2_k127_7678539_24 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 349.0
HKD2_k127_7678539_25 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 333.0
HKD2_k127_7678539_26 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 325.0
HKD2_k127_7678539_27 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 310.0
HKD2_k127_7678539_28 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 303.0
HKD2_k127_7678539_29 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 299.0
HKD2_k127_7678539_3 N-terminal domain of (some) glycogen debranching enzymes - - - 2.174e-319 993.0
HKD2_k127_7678539_30 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 292.0
HKD2_k127_7678539_31 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 304.0
HKD2_k127_7678539_32 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001761 278.0
HKD2_k127_7678539_33 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008599 275.0
HKD2_k127_7678539_34 Bacterial protein of unknown function (DUF898) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003043 269.0
HKD2_k127_7678539_35 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007886 248.0
HKD2_k127_7678539_36 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001279 253.0
HKD2_k127_7678539_37 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004088 247.0
HKD2_k127_7678539_38 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000009042 238.0
HKD2_k127_7678539_39 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000001439 231.0
HKD2_k127_7678539_4 AMP-binding enzyme C-terminal domain K00666,K02182,K20034 - 6.2.1.44,6.2.1.48 1.713e-280 870.0
HKD2_k127_7678539_40 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000001194 196.0
HKD2_k127_7678539_41 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000000000000007707 168.0
HKD2_k127_7678539_42 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000001887 170.0
HKD2_k127_7678539_43 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000905 175.0
HKD2_k127_7678539_44 PRC-barrel domain - - - 0.00000000000000000000000000000000000008814 149.0
HKD2_k127_7678539_45 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000009017 145.0
HKD2_k127_7678539_46 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000002146 139.0
HKD2_k127_7678539_47 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000003201 136.0
HKD2_k127_7678539_48 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000000000000003794 129.0
HKD2_k127_7678539_49 Cupredoxin-like domain - - - 0.00000000000000000000000007008 110.0
HKD2_k127_7678539_5 Belongs to the IlvD Edd family - - - 7.025e-274 852.0
HKD2_k127_7678539_50 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000001243 114.0
HKD2_k127_7678539_51 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000006812 106.0
HKD2_k127_7678539_52 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000002133 94.0
HKD2_k127_7678539_53 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000007107 88.0
HKD2_k127_7678539_54 - - - - 0.000000000000000007538 86.0
HKD2_k127_7678539_55 helix_turn_helix, Lux Regulon - - - 0.0000000000000003663 81.0
HKD2_k127_7678539_56 Extensin-like protein C-terminus - - - 0.000000000000001781 79.0
HKD2_k127_7678539_57 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000007646 70.0
HKD2_k127_7678539_58 PilZ domain - - - 0.0000000002981 64.0
HKD2_k127_7678539_6 ABC transporter transmembrane region K06147,K18893 - - 1.009e-260 816.0
HKD2_k127_7678539_60 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000001143 59.0
HKD2_k127_7678539_61 - - - - 0.00000386 51.0
HKD2_k127_7678539_62 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00001119 52.0
HKD2_k127_7678539_63 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0001671 49.0
HKD2_k127_7678539_64 Transglycosylase associated protein - - - 0.0002055 53.0
HKD2_k127_7678539_7 Acetyl-CoA dehydrogenase C-terminal like K00248,K00249,K20035 - 1.3.8.1,1.3.8.7 6.901e-241 757.0
HKD2_k127_7678539_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 1.193e-199 629.0
HKD2_k127_7678539_9 His Kinase A (phosphoacceptor) domain - - - 2.409e-198 645.0
HKD2_k127_7697307_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 485.0
HKD2_k127_7697307_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 319.0
HKD2_k127_7697307_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000007922 266.0
HKD2_k127_7697307_3 DNA polymerase III delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000003031 176.0
HKD2_k127_7697451_0 VWA domain containing CoxE-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 471.0
HKD2_k127_7697451_1 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 376.0
HKD2_k127_7697451_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 368.0
HKD2_k127_7697451_3 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 304.0
HKD2_k127_7697451_4 May be involved in the transport of PQQ or its precursor to the periplasm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008209 263.0
HKD2_k127_7697451_5 GYD domain - - - 0.0000000000000000000000000000000000000000000054 166.0
HKD2_k127_7713785_0 short-chain dehydrogenase reductase SDR K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000002595 257.0
HKD2_k127_7713785_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000001183 229.0
HKD2_k127_7713785_2 Class II Aldolase and Adducin N-terminal domain K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.00000000000000000000000000000000000000000000000000000000001331 217.0
HKD2_k127_7713785_3 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000000008473 205.0
HKD2_k127_7728324_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 347.0
HKD2_k127_7728324_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 331.0
HKD2_k127_7728324_2 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 286.0
HKD2_k127_7728324_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0000000000000000000000000001691 123.0
HKD2_k127_7732206_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 585.0
HKD2_k127_7732206_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000002043 185.0
HKD2_k127_7754291_0 heptosyltransferase K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007486 267.0
HKD2_k127_7754291_1 HIT domain - - - 0.0000000000000000000000000000000000000000000000003627 179.0
HKD2_k127_7754291_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.0000000000000000000000000002461 121.0
HKD2_k127_7755968_0 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 541.0
HKD2_k127_7755968_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 342.0
HKD2_k127_7755968_2 ABC transporter K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 323.0
HKD2_k127_7755968_3 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000006782 258.0
HKD2_k127_7755968_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000002173 136.0
HKD2_k127_7755968_5 Conserved carboxylase domain - - - 0.00000000000000000000000000000003142 127.0
HKD2_k127_7757728_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 514.0
HKD2_k127_7757728_1 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 398.0
HKD2_k127_7757728_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000009366 96.0
HKD2_k127_7757728_3 Antibiotic biosynthesis monooxygenase - - - 0.0000000000002239 77.0
HKD2_k127_7757728_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00001821 46.0
HKD2_k127_7767821_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 552.0
HKD2_k127_7767821_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 454.0
HKD2_k127_7767821_2 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000002686 230.0
HKD2_k127_7775358_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1703.0
HKD2_k127_7775358_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0 1038.0
HKD2_k127_7775358_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.00003359 47.0
HKD2_k127_7775358_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.603e-218 686.0
HKD2_k127_7775358_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 559.0
HKD2_k127_7775358_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 521.0
HKD2_k127_7775358_5 PFAM ABC transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 439.0
HKD2_k127_7775358_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 426.0
HKD2_k127_7775358_7 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 313.0
HKD2_k127_7775358_8 - K01992 - - 0.000000000000000000000000000000000000000000000008346 178.0
HKD2_k127_7775358_9 ATPases associated with a variety of cellular activities K01990 - - 0.0000000003495 62.0
HKD2_k127_7808799_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 565.0
HKD2_k127_7808799_1 YcjX-like family, DUF463 K06918 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 348.0
HKD2_k127_7808799_2 Inner membrane component domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004429 223.0
HKD2_k127_7834374_0 Pfam Transposase IS66 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 420.0
HKD2_k127_7834374_1 Protein of unknown function (DUF1134) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 286.0
HKD2_k127_7834374_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000009722 259.0
HKD2_k127_7834374_3 Histidine phosphotransferase C-terminal domain K13588 - - 0.000000000000000000000000000000000000000000000000000000001956 202.0
HKD2_k127_7834374_4 YHS domain protein - - - 0.000000000000000000000000000000000000000000001348 171.0
HKD2_k127_7871082_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 487.0
HKD2_k127_7871082_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 442.0
HKD2_k127_7871082_2 PFAM sugar isomerase (SIS) K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 325.0
HKD2_k127_7871082_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000002707 123.0
HKD2_k127_7933101_0 membrane - - - 0.0 1023.0
HKD2_k127_7933101_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005399 259.0
HKD2_k127_7933101_2 Glutathione S-transferase K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000008425 149.0
HKD2_k127_7933101_3 Aerotolerance regulator N-terminal - - - 0.00000000001893 63.0
HKD2_k127_7962967_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1015.0
HKD2_k127_7962967_1 Glycosyl hydrolases family 15 - - - 5.414e-273 852.0
HKD2_k127_7962967_10 Cytochrome c - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000662 108.0
HKD2_k127_7962967_11 SNARE associated Golgi protein - - - 0.0000000000000002753 90.0
HKD2_k127_7962967_2 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 563.0
HKD2_k127_7962967_3 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 413.0
HKD2_k127_7962967_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 384.0
HKD2_k127_7962967_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004386 268.0
HKD2_k127_7962967_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000001083 233.0
HKD2_k127_7962967_7 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000000000000000004335 172.0
HKD2_k127_7962967_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000000000000000000000622 172.0
HKD2_k127_7962967_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000005661 160.0
HKD2_k127_8038173_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 381.0
HKD2_k127_8038173_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000527 230.0
HKD2_k127_8038173_2 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.0008146 43.0
HKD2_k127_8046974_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 581.0
HKD2_k127_8046974_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 477.0
HKD2_k127_8046974_2 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 430.0
HKD2_k127_8046974_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 397.0
HKD2_k127_8046974_4 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 371.0
HKD2_k127_8090029_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 447.0
HKD2_k127_8090029_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 428.0
HKD2_k127_8090029_2 PFAM Glutathione S-transferase domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 366.0
HKD2_k127_8090029_3 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0000000000000000000000000004881 119.0
HKD2_k127_8090029_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000001979 91.0
HKD2_k127_8090029_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000003027 75.0
HKD2_k127_8090029_6 - - - - 0.0000000000004962 72.0
HKD2_k127_8090029_8 Protein of unknown function (DUF3551) - - - 0.0000003915 55.0
HKD2_k127_8090919_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.774e-228 711.0
HKD2_k127_8090919_1 cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 276.0
HKD2_k127_8103207_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0 1524.0
HKD2_k127_8103207_1 helicase superfamily c-terminal domain K17675 - 3.6.4.13 0.0 1315.0
HKD2_k127_8103207_10 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 516.0
HKD2_k127_8103207_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 507.0
HKD2_k127_8103207_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 503.0
HKD2_k127_8103207_13 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 474.0
HKD2_k127_8103207_14 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 417.0
HKD2_k127_8103207_15 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 412.0
HKD2_k127_8103207_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 412.0
HKD2_k127_8103207_17 KR domain K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 398.0
HKD2_k127_8103207_18 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 394.0
HKD2_k127_8103207_19 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
HKD2_k127_8103207_2 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.0 1180.0
HKD2_k127_8103207_20 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 380.0
HKD2_k127_8103207_21 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 379.0
HKD2_k127_8103207_22 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 354.0
HKD2_k127_8103207_23 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 342.0
HKD2_k127_8103207_24 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 343.0
HKD2_k127_8103207_25 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 340.0
HKD2_k127_8103207_26 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 313.0
HKD2_k127_8103207_27 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 305.0
HKD2_k127_8103207_28 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 297.0
HKD2_k127_8103207_29 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004708 291.0
HKD2_k127_8103207_3 Cobalamin biosynthesis protein CobT VWA domain K09883 - 6.6.1.2 2.02e-300 932.0
HKD2_k127_8103207_30 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002703 274.0
HKD2_k127_8103207_31 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005962 276.0
HKD2_k127_8103207_32 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000502 268.0
HKD2_k127_8103207_33 Polyhydroxyalkanoate synthesis repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008444 265.0
HKD2_k127_8103207_34 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000000000000138 227.0
HKD2_k127_8103207_35 Class II Aldolase and Adducin N-terminal domain K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.0000000000000000000000000000000000000000000000000000000000000005246 228.0
HKD2_k127_8103207_36 Belongs to the Nudix hydrolase family K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000009162 220.0
HKD2_k127_8103207_37 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000001793 222.0
HKD2_k127_8103207_38 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000005985 206.0
HKD2_k127_8103207_39 Cupin superfamily (DUF985) K09705 - - 0.00000000000000000000000000000000000000000000000000000000237 205.0
HKD2_k127_8103207_4 Belongs to the thiolase family K00626 - 2.3.1.9 4.824e-215 671.0
HKD2_k127_8103207_40 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000002144 203.0
HKD2_k127_8103207_41 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000000000000000000004025 198.0
HKD2_k127_8103207_42 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000007081 202.0
HKD2_k127_8103207_43 Domain of unknown function (DUF4167) - - - 0.0000000000000000000000000000000000000000000000000727 188.0
HKD2_k127_8103207_44 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000000000000000002308 185.0
HKD2_k127_8103207_45 Belongs to the BolA IbaG family K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000000000000000000000000001368 149.0
HKD2_k127_8103207_46 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000008811 143.0
HKD2_k127_8103207_47 Excinuclease ABC, C subunit K07461 - - 0.00000000000000000000000000000000805 128.0
HKD2_k127_8103207_48 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000001391 125.0
HKD2_k127_8103207_49 Phage integrase family - - - 0.0000000000000000000000000000121 131.0
HKD2_k127_8103207_5 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 5.688e-212 664.0
HKD2_k127_8103207_50 S4 domain K04762 - - 0.0000000000000000000000000007269 115.0
HKD2_k127_8103207_51 - - - - 0.000000000001224 68.0
HKD2_k127_8103207_52 - - - - 0.000000000001575 72.0
HKD2_k127_8103207_53 Putative mono-oxygenase ydhR - - - 0.000000000003776 72.0
HKD2_k127_8103207_54 - - - - 0.000000001226 64.0
HKD2_k127_8103207_55 ABC transporter substrate-binding protein K01999 - - 0.0000004239 52.0
HKD2_k127_8103207_6 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 1.47e-200 627.0
HKD2_k127_8103207_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 4.246e-196 619.0
HKD2_k127_8103207_8 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 604.0
HKD2_k127_8103207_9 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 569.0
HKD2_k127_8112101_0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 563.0
HKD2_k127_8112101_1 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 295.0
HKD2_k127_8112101_2 Domain of unknown function (DUF1932) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007416 255.0
HKD2_k127_8112101_3 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000005314 148.0
HKD2_k127_8141555_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1331.0
HKD2_k127_8141555_1 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 1.514e-205 645.0
HKD2_k127_8141555_10 PAP2 superfamily - - - 0.00000000000000000000000219 110.0
HKD2_k127_8141555_11 GIY-YIG catalytic domain K07461 - - 0.00000000000006798 74.0
HKD2_k127_8141555_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 552.0
HKD2_k127_8141555_3 Glucose / Sorbosone dehydrogenase K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 489.0
HKD2_k127_8141555_4 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 398.0
HKD2_k127_8141555_5 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 371.0
HKD2_k127_8141555_6 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 359.0
HKD2_k127_8141555_7 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000002482 155.0
HKD2_k127_8141555_8 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000001042 119.0
HKD2_k127_8141555_9 PAP2 superfamily - - - 0.000000000000000000000001825 107.0
HKD2_k127_8213283_0 Protein conserved in bacteria K09989 - - 8.768e-211 659.0
HKD2_k127_8213283_1 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 539.0
HKD2_k127_8213283_10 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000009669 211.0
HKD2_k127_8213283_11 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000003824 205.0
HKD2_k127_8213283_12 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000000000000000114 196.0
HKD2_k127_8213283_13 Flagellar biosynthesis repressor FlbT K06601 - - 0.00000000000000000000000000000000000000000000000000000387 194.0
HKD2_k127_8213283_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000002041 185.0
HKD2_k127_8213283_15 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000009123 185.0
HKD2_k127_8213283_16 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000131 186.0
HKD2_k127_8213283_17 helix_turn_helix, Lux Regulon K14987 - - 0.00000000000000000000000000000000000000000000000002031 187.0
HKD2_k127_8213283_18 Protein of unknown function (DUF968) - - - 0.0000000000000000000000000000000000000001604 156.0
HKD2_k127_8213283_19 Protein of unknown function (DUF2798) - - - 0.0000000000000000000000001977 108.0
HKD2_k127_8213283_2 HemN C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 494.0
HKD2_k127_8213283_20 ChaB K06197 - - 0.0000000000000000000000002078 108.0
HKD2_k127_8213283_21 - - - - 0.0000000000000000002748 89.0
HKD2_k127_8213283_22 - - - - 0.000000000000000002567 87.0
HKD2_k127_8213283_23 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.000000000000000004976 89.0
HKD2_k127_8213283_24 - - - - 0.00000000000000009495 88.0
HKD2_k127_8213283_26 - - - - 0.00000000002448 68.0
HKD2_k127_8213283_27 sequence-specific DNA binding - - - 0.000002438 49.0
HKD2_k127_8213283_28 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00001003 54.0
HKD2_k127_8213283_29 Phage-related minor tail protein K18642 - - 0.00005974 55.0
HKD2_k127_8213283_3 FAD dependent oxidoreductase K04755,K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 448.0
HKD2_k127_8213283_30 Glycosyl transferase family 41 - - - 0.0001912 48.0
HKD2_k127_8213283_31 Histidine kinase-like ATPases - - - 0.0007318 42.0
HKD2_k127_8213283_4 Membrane-associated sensor, integral membrane domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 414.0
HKD2_k127_8213283_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 368.0
HKD2_k127_8213283_6 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005535 286.0
HKD2_k127_8213283_7 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001508 241.0
HKD2_k127_8213283_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000004699 232.0
HKD2_k127_8213283_9 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000002124 223.0
HKD2_k127_8217550_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.283e-239 753.0
HKD2_k127_8217550_1 Hydrolase CocE NonD family K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 430.0
HKD2_k127_8217550_2 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000001416 138.0
HKD2_k127_8263973_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 4.358e-228 710.0
HKD2_k127_8263973_1 glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 464.0
HKD2_k127_8263973_2 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 314.0
HKD2_k127_8263973_3 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.000000000000000000000000000000000000000000000000000005832 198.0
HKD2_k127_8263973_4 ErfK YbiS YcfS YnhG - - - 0.0000000000000000000000000000000000000000000000003037 179.0
HKD2_k127_8263973_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000605 137.0
HKD2_k127_8263973_7 Chemotaxis phosphatase, CheZ K03414 - - 0.0000000000000000000000000007939 117.0
HKD2_k127_8316487_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2306.0
HKD2_k127_8316487_1 Major Facilitator Superfamily K02575 - - 0.0 1579.0
HKD2_k127_8316487_10 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 319.0
HKD2_k127_8316487_11 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 289.0
HKD2_k127_8316487_12 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006733 275.0
HKD2_k127_8316487_13 Nitrate reductase, delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007025 259.0
HKD2_k127_8316487_14 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000008447 169.0
HKD2_k127_8316487_15 - - - - 0.0000000000000004271 81.0
HKD2_k127_8316487_17 Acyltransferase family - - - 0.0000000255 57.0
HKD2_k127_8316487_2 Nitrate reductase beta subunit K00371 - 1.7.5.1 2.353e-317 974.0
HKD2_k127_8316487_3 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 2.834e-225 706.0
HKD2_k127_8316487_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP - - - 1.413e-205 648.0
HKD2_k127_8316487_5 DNA polymerase beta thumb K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 568.0
HKD2_k127_8316487_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
HKD2_k127_8316487_7 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 413.0
HKD2_k127_8316487_8 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 367.0
HKD2_k127_8316487_9 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 352.0
HKD2_k127_8396398_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 6.38e-222 691.0
HKD2_k127_8396398_1 COG0714 MoxR-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 458.0
HKD2_k127_8396398_2 VWA domain containing CoxE-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 307.0
HKD2_k127_8433859_0 Elongation factor G, domain IV K02355 - - 0.0 1046.0
HKD2_k127_8433859_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000001638 233.0
HKD2_k127_8433859_2 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.000000000000000000000239 96.0
HKD2_k127_8462683_0 ABC-2 family transporter protein K01990,K13926 - - 0.0 1294.0
HKD2_k127_8462683_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 609.0
HKD2_k127_8462683_10 Transcriptional regulator K13771 - - 0.000000000000000000000000000000000000000000000000000000000000006576 219.0
HKD2_k127_8462683_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000009169 146.0
HKD2_k127_8462683_12 - - - - 0.000000000000000000000000000000002124 136.0
HKD2_k127_8462683_13 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000004478 132.0
HKD2_k127_8462683_14 Domain of unknown function (DUF1127) - - - 0.00001083 51.0
HKD2_k127_8462683_15 - - - - 0.000877 44.0
HKD2_k127_8462683_2 carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 602.0
HKD2_k127_8462683_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 504.0
HKD2_k127_8462683_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009609 496.0
HKD2_k127_8462683_5 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 481.0
HKD2_k127_8462683_6 secretion protein K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 439.0
HKD2_k127_8462683_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 322.0
HKD2_k127_8462683_8 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001507 284.0
HKD2_k127_8462683_9 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005907 258.0
HKD2_k127_8653505_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1633.0
HKD2_k127_8653505_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1540.0
HKD2_k127_8653505_10 Transaldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 380.0
HKD2_k127_8653505_11 EamA-like transporter family K15270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 352.0
HKD2_k127_8653505_12 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008357 258.0
HKD2_k127_8653505_13 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000000000002478 233.0
HKD2_k127_8653505_14 YtkA-like - - - 0.00000000000000000000000000000000000000000000003957 173.0
HKD2_k127_8653505_15 UDP binding domain K02474 - - 0.000000000000000000000001768 103.0
HKD2_k127_8653505_16 Cytochrome C' - - - 0.00000000000000306 80.0
HKD2_k127_8653505_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.289e-315 982.0
HKD2_k127_8653505_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.461e-201 640.0
HKD2_k127_8653505_4 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 7.987e-200 632.0
HKD2_k127_8653505_5 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 531.0
HKD2_k127_8653505_6 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 513.0
HKD2_k127_8653505_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 513.0
HKD2_k127_8653505_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 502.0
HKD2_k127_8653505_9 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 506.0
HKD2_k127_87348_0 Belongs to the FPP GGPP synthase family K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 370.0
HKD2_k127_87348_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
HKD2_k127_8792574_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.228e-320 991.0
HKD2_k127_8792574_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 612.0
HKD2_k127_8792574_2 Phosphoglycerate kinase K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 604.0
HKD2_k127_8792574_3 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 573.0
HKD2_k127_8792574_4 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 447.0
HKD2_k127_8792574_5 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 386.0
HKD2_k127_8792574_6 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 326.0
HKD2_k127_8792574_7 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000001087 221.0
HKD2_k127_8792574_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000000004074 142.0
HKD2_k127_8792574_9 Domain of unknown function (DUF4164) - - - 0.00000000000000000000001213 103.0
HKD2_k127_8868404_0 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 583.0
HKD2_k127_8868404_1 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 544.0
HKD2_k127_8868404_2 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 351.0
HKD2_k127_8868404_3 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 298.0
HKD2_k127_8868404_4 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000001543 232.0
HKD2_k127_8868404_5 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000001943 178.0
HKD2_k127_8868404_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000002886 173.0
HKD2_k127_8868404_7 Pfam Transposase IS66 - - - 0.0000000000000000000000000000000003665 137.0
HKD2_k127_8868404_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000387 59.0
HKD2_k127_8944614_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.051e-234 738.0
HKD2_k127_8944614_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 419.0
HKD2_k127_8944614_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 381.0
HKD2_k127_8944614_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 366.0
HKD2_k127_8944614_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 301.0
HKD2_k127_8958842_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.548e-243 759.0
HKD2_k127_8958842_1 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000002496 228.0
HKD2_k127_8958842_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000003529 151.0
HKD2_k127_8969464_0 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 435.0
HKD2_k127_8969464_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009853 247.0
HKD2_k127_8969464_2 Cupin domain - - - 0.0000000000000000000000000000000001499 135.0
HKD2_k127_8980852_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 611.0
HKD2_k127_8980852_1 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000004773 194.0
HKD2_k127_8980852_2 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K01784,K03274 - 5.1.3.2,5.1.3.20 0.0000000000008019 68.0
HKD2_k127_8987465_0 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 444.0
HKD2_k127_8987465_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 323.0
HKD2_k127_8987465_2 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 250.0
HKD2_k127_8987465_3 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000002249 191.0
HKD2_k127_8987465_4 Protein of unknown function (DUF2927) - - - 0.00000000000000000000000000000000000001773 153.0
HKD2_k127_8990911_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 338.0
HKD2_k127_8990911_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 320.0
HKD2_k127_8990911_2 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003125 280.0
HKD2_k127_8990911_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001245 282.0
HKD2_k127_8990911_4 Extracellular liganD-binding receptor K01999 - - 0.000000004011 59.0
HKD2_k127_8991897_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.992e-227 709.0
HKD2_k127_8991897_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 1.718e-209 657.0
HKD2_k127_8991897_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 538.0
HKD2_k127_8991897_3 FMN-dependent dehydrogenase K00101 - 1.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 533.0
HKD2_k127_8991897_4 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008898 274.0
HKD2_k127_9019833_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.989e-227 713.0
HKD2_k127_9019833_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000008414 162.0
HKD2_k127_9019833_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000009691 96.0
HKD2_k127_9029736_0 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003872 283.0
HKD2_k127_9029736_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000002363 138.0
HKD2_k127_9029736_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000002217 127.0
HKD2_k127_9054125_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 322.0
HKD2_k127_9054125_1 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 323.0
HKD2_k127_9054125_2 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000004106 180.0
HKD2_k127_9102805_0 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 447.0
HKD2_k127_9102805_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000001433 229.0
HKD2_k127_9102805_2 Carbohydrate-selective porin, OprB family K16080 - - 0.0000000001984 67.0
HKD2_k127_9106551_0 Dehydratase family K22186 - 4.2.1.82 1.739e-318 983.0
HKD2_k127_9106551_1 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 5.955e-269 854.0
HKD2_k127_9106551_10 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 337.0
HKD2_k127_9106551_11 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 330.0
HKD2_k127_9106551_12 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 299.0
HKD2_k127_9106551_13 ABC-type branched-chain amino acid transport K01999 - - 0.0000000000000000000000000000000000000000001753 178.0
HKD2_k127_9106551_14 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000002951 143.0
HKD2_k127_9106551_15 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.000000000000000000000000000000003716 135.0
HKD2_k127_9106551_16 - - - - 0.000000000000000000000008043 106.0
HKD2_k127_9106551_17 sulfur carrier activity K04085 - - 0.0000000000000000001167 92.0
HKD2_k127_9106551_18 outer membrane protein, TolC K12340 - - 0.0000000000000003735 81.0
HKD2_k127_9106551_19 - - - - 0.0000000000009551 72.0
HKD2_k127_9106551_2 Extracellular solute-binding protein K02027 - - 8.357e-215 674.0
HKD2_k127_9106551_20 Sodium:sulfate symporter transmembrane region - - - 0.000000000002557 74.0
HKD2_k127_9106551_21 Glycine zipper - - - 0.000000003612 61.0
HKD2_k127_9106551_3 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 586.0
HKD2_k127_9106551_4 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 538.0
HKD2_k127_9106551_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 505.0
HKD2_k127_9106551_6 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 457.0
HKD2_k127_9106551_7 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 430.0
HKD2_k127_9106551_8 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 394.0
HKD2_k127_9106551_9 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 371.0
HKD2_k127_9107386_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4 9.182e-284 888.0
HKD2_k127_9107386_1 phosphate acetyltransferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 432.0
HKD2_k127_9107386_2 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 399.0
HKD2_k127_9107386_3 4Fe-4S ferredoxin, iron-sulfur binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000007257 226.0
HKD2_k127_9107386_4 FixH - - - 0.0000000000000000000000000000000000000103 151.0
HKD2_k127_9107386_5 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000000000003484 81.0
HKD2_k127_9125993_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 588.0
HKD2_k127_9125993_1 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 578.0
HKD2_k127_9125993_2 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 433.0
HKD2_k127_9125993_3 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009413 266.0
HKD2_k127_9125993_4 - - - - 0.00000000000000000000000000000001018 134.0
HKD2_k127_9125993_5 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000005642 101.0
HKD2_k127_9125993_6 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00000000000004407 84.0
HKD2_k127_9125993_7 - - - - 0.00000004816 58.0
HKD2_k127_9136009_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 471.0
HKD2_k127_9136009_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008085 267.0
HKD2_k127_9136009_2 quinone reductase - - - 0.00000000000000000001751 92.0
HKD2_k127_9170051_0 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 424.0
HKD2_k127_9170051_1 Glycosyl transferase family group 2 K03669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002079 284.0
HKD2_k127_9170051_2 6-pyruvoyl tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000005708 213.0
HKD2_k127_918419_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.645e-319 997.0
HKD2_k127_918419_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 8.465e-273 845.0
HKD2_k127_918419_10 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 529.0
HKD2_k127_918419_11 Permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 469.0
HKD2_k127_918419_12 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 452.0
HKD2_k127_918419_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 445.0
HKD2_k127_918419_14 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 449.0
HKD2_k127_918419_15 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 439.0
HKD2_k127_918419_16 Permease K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 436.0
HKD2_k127_918419_17 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 418.0
HKD2_k127_918419_18 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 392.0
HKD2_k127_918419_19 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 393.0
HKD2_k127_918419_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.115e-270 841.0
HKD2_k127_918419_20 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 376.0
HKD2_k127_918419_21 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 325.0
HKD2_k127_918419_22 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 294.0
HKD2_k127_918419_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 288.0
HKD2_k127_918419_24 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000943 267.0
HKD2_k127_918419_25 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000004753 263.0
HKD2_k127_918419_26 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007392 251.0
HKD2_k127_918419_27 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000143 239.0
HKD2_k127_918419_28 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002138 238.0
HKD2_k127_918419_29 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
HKD2_k127_918419_3 ABC transporter K06158 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 2.154e-256 804.0
HKD2_k127_918419_30 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000000000000000000001844 184.0
HKD2_k127_918419_31 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000002034 185.0
HKD2_k127_918419_32 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000003486 153.0
HKD2_k127_918419_33 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000009529 148.0
HKD2_k127_918419_34 GrpB protein - - - 0.00000000000000000000000000003093 119.0
HKD2_k127_918419_35 - - - - 0.000000000000000001138 95.0
HKD2_k127_918419_36 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A - - - 0.0000000000000001748 80.0
HKD2_k127_918419_37 - - - - 0.0000000000000006027 85.0
HKD2_k127_918419_38 - - - - 0.000000000000001581 88.0
HKD2_k127_918419_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.271e-244 762.0
HKD2_k127_918419_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.207e-232 727.0
HKD2_k127_918419_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 2.456e-226 713.0
HKD2_k127_918419_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 4.04e-224 699.0
HKD2_k127_918419_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.757e-209 658.0
HKD2_k127_918419_9 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 1.664e-196 619.0
HKD2_k127_9185109_0 MmgE PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 305.0
HKD2_k127_9185109_1 PFAM Methyltransferase type 11 - - - 0.0001907 45.0
HKD2_k127_9186231_0 ATPase (P-type) K01535 - 3.6.3.6 0.0 1135.0
HKD2_k127_9186231_1 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 582.0
HKD2_k127_9186231_10 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000001452 216.0
HKD2_k127_9186231_11 membrane K08988 - - 0.0000000000000000000000000000000000000000000000000000004509 202.0
HKD2_k127_9186231_12 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000001311 194.0
HKD2_k127_9186231_13 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000002407 170.0
HKD2_k127_9186231_14 Opacity protein and related surface antigens K16079 - - 0.000000000000000000000000000000000000000001935 165.0
HKD2_k127_9186231_15 Sel1-like repeats. - - - 0.0000000000000000000000001316 113.0
HKD2_k127_9186231_16 Cytochrome c - - - 0.000000000000000002009 88.0
HKD2_k127_9186231_17 - - - - 0.00000001919 59.0
HKD2_k127_9186231_18 Metallo-beta-lactamase superfamily - - - 0.000004761 53.0
HKD2_k127_9186231_19 Domain of unknown function (DUF1330) - - - 0.00001018 53.0
HKD2_k127_9186231_2 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 545.0
HKD2_k127_9186231_20 - - - - 0.00009637 49.0
HKD2_k127_9186231_21 - - - - 0.0002378 45.0
HKD2_k127_9186231_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 389.0
HKD2_k127_9186231_4 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 351.0
HKD2_k127_9186231_5 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 340.0
HKD2_k127_9186231_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 323.0
HKD2_k127_9186231_7 COG0790 FOG TPR repeat, SEL1 subfamily K07126 GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000189 272.0
HKD2_k127_9186231_8 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003491 266.0
HKD2_k127_9186231_9 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000497 260.0
HKD2_k127_9200624_0 Biotin carboxylase C-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.572e-254 788.0
HKD2_k127_9200624_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 332.0
HKD2_k127_9200624_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000001549 199.0
HKD2_k127_9200624_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000000000000000000003081 184.0
HKD2_k127_9200624_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000008664 69.0
HKD2_k127_9290699_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469 - 3.5.2.9 0.0 1823.0
HKD2_k127_9290699_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1588.0
HKD2_k127_9290699_10 Peptidase M16 inactive domain K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 505.0
HKD2_k127_9290699_11 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 496.0
HKD2_k127_9290699_12 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 471.0
HKD2_k127_9290699_13 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 472.0
HKD2_k127_9290699_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 479.0
HKD2_k127_9290699_15 Histidyl-tRNA synthetase K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 467.0
HKD2_k127_9290699_16 Alpha beta hydrolase K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 454.0
HKD2_k127_9290699_17 Putative diguanylate phosphodiesterase K13593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 426.0
HKD2_k127_9290699_18 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 378.0
HKD2_k127_9290699_19 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 373.0
HKD2_k127_9290699_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.531e-282 879.0
HKD2_k127_9290699_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 364.0
HKD2_k127_9290699_21 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 336.0
HKD2_k127_9290699_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 297.0
HKD2_k127_9290699_23 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000029 286.0
HKD2_k127_9290699_24 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001182 261.0
HKD2_k127_9290699_25 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000000000000509 236.0
HKD2_k127_9290699_26 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000006484 242.0
HKD2_k127_9290699_27 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000006111 199.0
HKD2_k127_9290699_28 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000001444 198.0
HKD2_k127_9290699_29 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000000000000000003043 192.0
HKD2_k127_9290699_3 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 1.323e-232 729.0
HKD2_k127_9290699_30 - - - - 0.00000000000000000000000000000000000000008557 157.0
HKD2_k127_9290699_31 Inositol monophosphatase - - - 0.000000000000000000000000000000004856 130.0
HKD2_k127_9290699_32 - - - - 0.000000000000000000000000000002125 130.0
HKD2_k127_9290699_33 Uncharacterized protein conserved in bacteria (DUF2093) - - - 0.0000000000000000000000000002946 116.0
HKD2_k127_9290699_34 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000001342 118.0
HKD2_k127_9290699_35 - - - - 0.00000000000000000000000000308 116.0
HKD2_k127_9290699_36 SnoaL-like domain - - - 0.000000000000000000005088 97.0
HKD2_k127_9290699_37 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.000000000000001906 79.0
HKD2_k127_9290699_38 - - - - 0.0000007588 51.0
HKD2_k127_9290699_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 4.011e-228 713.0
HKD2_k127_9290699_5 Belongs to the GARS family K01945 - 6.3.4.13 7.038e-206 647.0
HKD2_k127_9290699_6 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 6.517e-205 646.0
HKD2_k127_9290699_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 607.0
HKD2_k127_9290699_8 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 585.0
HKD2_k127_9290699_9 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 576.0
HKD2_k127_9340335_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 7.74e-310 957.0
HKD2_k127_9340335_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 475.0
HKD2_k127_9340335_2 - - - - 0.00000000000000000000008889 100.0
HKD2_k127_9340335_3 Outer membrane protein beta-barrel domain K16079 - - 0.00000000000000000001614 93.0
HKD2_k127_9340335_4 Ribbon-helix-helix domain - - - 0.00000000000000000003746 94.0
HKD2_k127_9340335_5 Outer membrane protein beta-barrel domain K16079 - - 0.0000000000000007195 81.0
HKD2_k127_9340335_6 - - - - 0.000000000000001787 83.0
HKD2_k127_9363693_0 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 578.0
HKD2_k127_9363693_1 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 360.0
HKD2_k127_9363693_2 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00005332 45.0
HKD2_k127_9382464_0 Biotin carboxylase C-terminal domain K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 0.0 1035.0
HKD2_k127_9382464_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 551.0
HKD2_k127_9382464_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 338.0
HKD2_k127_9382464_3 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001929 278.0
HKD2_k127_9382464_4 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000005757 196.0
HKD2_k127_9382464_5 arylsulfatase activity K01083,K01126 - 3.1.3.8,3.1.4.46 0.000000000000000000000000000000000000000000000004692 182.0
HKD2_k127_9382464_6 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000007381 120.0
HKD2_k127_9382464_7 AIG2-like family - - - 0.0000000000000000000000000001474 119.0
HKD2_k127_9396268_0 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 412.0
HKD2_k127_9396268_1 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 417.0
HKD2_k127_9396268_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 353.0
HKD2_k127_9396268_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 256.0
HKD2_k127_9396268_4 PFAM monooxygenase FAD-binding - - - 0.00000000000000000000000000000000000000000000000001456 185.0
HKD2_k127_9396268_5 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000002318 181.0
HKD2_k127_9439600_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1395.0
HKD2_k127_9439600_1 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.0 1011.0
HKD2_k127_9439600_10 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000005124 222.0
HKD2_k127_9439600_11 Protein of unknown function (DUF2497) K09991 - - 0.00000000000000000000000000000000000000000000000000000002917 204.0
HKD2_k127_9439600_12 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000001411 160.0
HKD2_k127_9439600_13 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.0000000000001553 82.0
HKD2_k127_9439600_14 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000004596 56.0
HKD2_k127_9439600_15 transferase activity, transferring glycosyl groups - - - 0.000000308 53.0
HKD2_k127_9439600_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.718e-256 799.0
HKD2_k127_9439600_3 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 564.0
HKD2_k127_9439600_4 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 413.0
HKD2_k127_9439600_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 391.0
HKD2_k127_9439600_6 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 313.0
HKD2_k127_9439600_7 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 306.0
HKD2_k127_9439600_8 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009922 313.0
HKD2_k127_9439600_9 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000377 233.0
HKD2_k127_9463090_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 7.357e-255 794.0
HKD2_k127_9465512_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.0 1134.0
HKD2_k127_9465512_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.085e-304 948.0
HKD2_k127_9465512_10 ChrA protein K07240 - - 0.0000000002945 62.0
HKD2_k127_9465512_11 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000001897 53.0
HKD2_k127_9465512_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 557.0
HKD2_k127_9465512_3 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 492.0
HKD2_k127_9465512_4 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 293.0
HKD2_k127_9465512_5 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 296.0
HKD2_k127_9465512_6 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009064 276.0
HKD2_k127_9465512_7 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000001057 156.0
HKD2_k127_9465512_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000001486 144.0
HKD2_k127_9465512_9 - - - - 0.0000000000002219 72.0
HKD2_k127_9491879_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.849e-226 709.0
HKD2_k127_9491879_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 571.0
HKD2_k127_9491879_10 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000000000000006096 158.0
HKD2_k127_9491879_11 Belongs to the UPF0335 family - - - 0.000000000000000000000000000000003878 131.0
HKD2_k127_9491879_12 RmlD substrate binding domain K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000009871 68.0
HKD2_k127_9491879_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000006191 76.0
HKD2_k127_9491879_2 Methionine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 497.0
HKD2_k127_9491879_3 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 431.0
HKD2_k127_9491879_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 437.0
HKD2_k127_9491879_5 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 389.0
HKD2_k127_9491879_6 Major facilitator Superfamily K07165,K08195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 348.0
HKD2_k127_9491879_7 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 309.0
HKD2_k127_9491879_8 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006491 262.0
HKD2_k127_9491879_9 Protein of unknown function (DUF1036) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009934 250.0
HKD2_k127_9626687_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 332.0
HKD2_k127_9626687_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000005419 202.0
HKD2_k127_9626687_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000001417 186.0
HKD2_k127_9626687_3 - - - - 0.0000000000000000000000000000000000000000000000269 179.0
HKD2_k127_9630895_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000219 209.0
HKD2_k127_9630895_1 leucine import across plasma membrane K01997 - - 0.000000000000000000000000000000000000000000000000000133 196.0
HKD2_k127_9630895_2 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000001048 104.0
HKD2_k127_9630895_3 amino acid K01995 - - 0.00000000000001083 86.0
HKD2_k127_9676657_0 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 312.0
HKD2_k127_9676657_1 periplasmic protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001237 292.0
HKD2_k127_9676657_2 NifU-like N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004987 248.0
HKD2_k127_9676657_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000001193 222.0
HKD2_k127_9792257_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1185.0
HKD2_k127_9792257_1 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 6.237e-229 724.0
HKD2_k127_9792257_10 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 344.0
HKD2_k127_9792257_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 295.0
HKD2_k127_9792257_12 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 283.0
HKD2_k127_9792257_13 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000618 269.0
HKD2_k127_9792257_14 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008981 271.0
HKD2_k127_9792257_15 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000003346 241.0
HKD2_k127_9792257_16 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000000000000007603 193.0
HKD2_k127_9792257_17 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.0000000000000000000000000000000000000000000000000006691 192.0
HKD2_k127_9792257_18 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000003076 188.0
HKD2_k127_9792257_19 Domain of unknown function (DUF4332) - - - 0.00000000000000000000000000000000000000000004928 164.0
HKD2_k127_9792257_2 Peptidase dimerisation domain K01436 - - 4.759e-203 642.0
HKD2_k127_9792257_20 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000006413 154.0
HKD2_k127_9792257_21 Haem-degrading - - - 0.000000000000000000000000000000000005488 143.0
HKD2_k127_9792257_22 - - - - 0.00000000000000000000000000000000009187 138.0
HKD2_k127_9792257_23 Cytochrome c - - - 0.00000000000000000000004477 107.0
HKD2_k127_9792257_24 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000001358 83.0
HKD2_k127_9792257_25 - - - - 0.0000006938 56.0
HKD2_k127_9792257_26 Right handed beta helix region - - - 0.000004111 50.0
HKD2_k127_9792257_3 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 510.0
HKD2_k127_9792257_4 radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 472.0
HKD2_k127_9792257_5 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 469.0
HKD2_k127_9792257_6 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 467.0
HKD2_k127_9792257_7 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 462.0
HKD2_k127_9792257_8 transport, permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 400.0
HKD2_k127_9792257_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941,K18824 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 366.0
HKD2_k127_98699_0 MmgE/PrpD family - - - 4.297e-245 762.0
HKD2_k127_98699_1 Binding-protein-dependent transport system inner membrane component K02011 - - 4.774e-241 762.0
HKD2_k127_98699_10 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 392.0
HKD2_k127_98699_11 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 376.0
HKD2_k127_98699_12 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 376.0
HKD2_k127_98699_13 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007598 375.0
HKD2_k127_98699_14 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 370.0
HKD2_k127_98699_15 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 362.0
HKD2_k127_98699_16 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 305.0
HKD2_k127_98699_17 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000001948 224.0
HKD2_k127_98699_18 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
HKD2_k127_98699_19 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000002158 138.0
HKD2_k127_98699_2 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.432e-211 666.0
HKD2_k127_98699_20 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000002174 88.0
HKD2_k127_98699_3 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520 - 1.2.5.3 2.994e-208 672.0
HKD2_k127_98699_4 inositol 2-dehydrogenase activity K18106 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 565.0
HKD2_k127_98699_5 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 563.0
HKD2_k127_98699_6 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 533.0
HKD2_k127_98699_7 ABC-type Fe3 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 507.0
HKD2_k127_98699_8 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 426.0
HKD2_k127_98699_9 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 387.0