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Overview

ID MAG01792
Name HKD2_bin.34
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Verrucomicrobiota
Class Verrucomicrobiia
Order Chthoniobacterales
Family UBA10450
Genus Udaeobacter
Species
Assembly information
Completeness (%) 93.77
Contamination (%) 0.97
GC content (%) 55.0
N50 (bp) 17,701
Genome size (bp) 3,134,456

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2752

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10024428_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 451.0
HKD2_k127_10024428_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 352.0
HKD2_k127_10024428_10 AntiSigma factor - - - 0.00001987 55.0
HKD2_k127_10024428_11 Tetratricopeptide repeat - - - 0.0001913 53.0
HKD2_k127_10024428_12 Serine aminopeptidase, S33 K06889 - - 0.0002073 50.0
HKD2_k127_10024428_2 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003658 255.0
HKD2_k127_10024428_3 Sigma-70, region 4 - - - 0.0000000000000000000000000000000000000003812 156.0
HKD2_k127_10024428_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000003005 102.0
HKD2_k127_10024428_6 - - - - 0.0000000000000000008332 96.0
HKD2_k127_10024428_7 RNA-binding protein - - - 0.00000000000003351 74.0
HKD2_k127_10024428_8 Dienelactone hydrolase family - - - 0.00000003014 66.0
HKD2_k127_100493_0 thiamine-containing compound biosynthetic process K02051,K15553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 577.0
HKD2_k127_100493_1 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 475.0
HKD2_k127_100493_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 468.0
HKD2_k127_100493_3 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008992 452.0
HKD2_k127_100493_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 422.0
HKD2_k127_100493_5 Ring hydroxylating alpha subunit (catalytic domain) K16968 - 1.14.13.111 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 294.0
HKD2_k127_1018167_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 610.0
HKD2_k127_1018167_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 422.0
HKD2_k127_1018167_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 403.0
HKD2_k127_1018167_3 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000002052 241.0
HKD2_k127_1018167_4 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.000000000000000000000000000000000000000000000000000000007535 208.0
HKD2_k127_1018167_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000008042 154.0
HKD2_k127_1018167_6 Phosphodiester glycosidase - - - 0.000000000000000000000000005951 121.0
HKD2_k127_1018167_7 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000001599 87.0
HKD2_k127_1029787_0 AcrB/AcrD/AcrF family - - - 0.0 1375.0
HKD2_k127_1029787_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 302.0
HKD2_k127_1029787_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000003814 207.0
HKD2_k127_1029787_3 Protein of unknown function (DUF2892) - - - 0.000000000000000000549 89.0
HKD2_k127_1092327_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 5.316e-240 750.0
HKD2_k127_1092327_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 9.282e-206 656.0
HKD2_k127_1092327_10 Bacterial lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005666 251.0
HKD2_k127_1092327_11 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
HKD2_k127_1092327_12 Ami_3 - - - 0.00000000000000000000000000000000000000000000000006085 185.0
HKD2_k127_1092327_13 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000007138 190.0
HKD2_k127_1092327_14 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000002233 154.0
HKD2_k127_1092327_15 cellulase activity - - - 0.000000000000000000000000000000000000001062 161.0
HKD2_k127_1092327_16 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000008369 121.0
HKD2_k127_1092327_17 Chaperone of endosialidase - - - 0.0005528 49.0
HKD2_k127_1092327_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 602.0
HKD2_k127_1092327_3 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 574.0
HKD2_k127_1092327_4 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 445.0
HKD2_k127_1092327_5 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 436.0
HKD2_k127_1092327_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 403.0
HKD2_k127_1092327_7 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 345.0
HKD2_k127_1092327_8 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 346.0
HKD2_k127_1092327_9 Glucose-6-phosphate dehydrogenase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004246 269.0
HKD2_k127_113822_0 - - - - 0.00000000000000000000000000000000000007849 146.0
HKD2_k127_113822_1 LTXXQ motif family protein K07803 - - 0.0000000000000000000000000000000006595 137.0
HKD2_k127_113822_2 Tripartite ATP-independent periplasmic transporter, DctM component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 0.0000000000000000000000006344 104.0
HKD2_k127_113822_3 EF hand - - - 0.000000000000000000000008376 110.0
HKD2_k127_1218996_0 Cell wall formation - - - 7.185e-297 931.0
HKD2_k127_1218996_1 Peptidase dimerisation domain - - - 6.859e-247 770.0
HKD2_k127_1218996_10 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002574 268.0
HKD2_k127_1218996_11 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001131 263.0
HKD2_k127_1218996_12 OsmC-like protein K04063 - - 0.0000000000000000000000000000000000000000000005925 169.0
HKD2_k127_1218996_13 Cupin - - - 0.0000000000000000000000000006561 117.0
HKD2_k127_1218996_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000311 105.0
HKD2_k127_1218996_15 Lysin motif - - - 0.000000000008715 74.0
HKD2_k127_1218996_2 DNA polymerase type-B family K02336 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 609.0
HKD2_k127_1218996_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 584.0
HKD2_k127_1218996_4 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 462.0
HKD2_k127_1218996_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 439.0
HKD2_k127_1218996_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 405.0
HKD2_k127_1218996_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 383.0
HKD2_k127_1218996_8 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 332.0
HKD2_k127_1218996_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 325.0
HKD2_k127_1282476_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 6.846e-266 827.0
HKD2_k127_1282476_1 phosphoribosyltransferase K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
HKD2_k127_1282476_2 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000007608 223.0
HKD2_k127_1282476_3 Universal stress protein family - - - 0.00000000000000001191 89.0
HKD2_k127_1282555_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 479.0
HKD2_k127_1282555_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 314.0
HKD2_k127_1282555_2 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 289.0
HKD2_k127_1282555_3 PFAM Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000001264 233.0
HKD2_k127_1282555_4 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000007902 148.0
HKD2_k127_1282555_5 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000001616 143.0
HKD2_k127_1282555_6 Trypsin-like peptidase domain - - - 0.00000000000000001188 95.0
HKD2_k127_1282555_7 Universal stress protein - - - 0.0001541 48.0
HKD2_k127_1293046_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 607.0
HKD2_k127_1293046_1 phosphoglycolate phosphatase activity K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003025 276.0
HKD2_k127_1293046_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000005162 168.0
HKD2_k127_1305175_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 5.686e-272 849.0
HKD2_k127_1305175_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 421.0
HKD2_k127_1305175_10 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000004567 174.0
HKD2_k127_1305175_11 Stress responsive A/B Barrel Domain - - - 0.000000000000000000000000000000000003548 140.0
HKD2_k127_1305175_12 methyltransferase - - - 0.00000000000000000000000001092 119.0
HKD2_k127_1305175_13 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.000000001039 63.0
HKD2_k127_1305175_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 391.0
HKD2_k127_1305175_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 368.0
HKD2_k127_1305175_4 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 360.0
HKD2_k127_1305175_5 Family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 357.0
HKD2_k127_1305175_6 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 318.0
HKD2_k127_1305175_7 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001092 280.0
HKD2_k127_1305175_8 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000003473 248.0
HKD2_k127_1305175_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000003906 236.0
HKD2_k127_1322051_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
HKD2_k127_1322051_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000007498 252.0
HKD2_k127_1322051_2 AraC-binding-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000003347 224.0
HKD2_k127_1322051_3 cyclic nucleotide binding K01420 - - 0.00000000000000000000000000000000000000000000000003482 187.0
HKD2_k127_1322051_4 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000008595 152.0
HKD2_k127_1322051_5 PFAM SMP-30 Gluconolaconase - - - 0.000000000001365 70.0
HKD2_k127_1330167_0 AcrB/AcrD/AcrF family - - - 0.0 1318.0
HKD2_k127_1330167_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 438.0
HKD2_k127_1330167_10 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000225 223.0
HKD2_k127_1330167_11 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000001061 220.0
HKD2_k127_1330167_12 TOBE domain K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000002576 204.0
HKD2_k127_1330167_13 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000007601 145.0
HKD2_k127_1330167_14 outer membrane efflux protein K03287 - - 0.00000000000006252 84.0
HKD2_k127_1330167_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 436.0
HKD2_k127_1330167_3 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 344.0
HKD2_k127_1330167_4 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 315.0
HKD2_k127_1330167_5 ornithine cyclodeaminase activity K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 307.0
HKD2_k127_1330167_6 Pyruvate phosphate dikinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003196 272.0
HKD2_k127_1330167_7 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004981 265.0
HKD2_k127_1330167_8 Alpha-aspartyl dipeptidase-like K05995 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.4.13.21 0.00000000000000000000000000000000000000000000000000000000000000000000002711 248.0
HKD2_k127_1330167_9 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001138 224.0
HKD2_k127_134755_0 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 374.0
HKD2_k127_134755_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 335.0
HKD2_k127_134755_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000007553 124.0
HKD2_k127_134755_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000009103 117.0
HKD2_k127_134755_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000004082 88.0
HKD2_k127_1381548_0 thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate K01130 - 3.1.6.1 1.389e-281 889.0
HKD2_k127_1381548_1 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 473.0
HKD2_k127_1381548_10 protease - - - 0.00000002956 66.0
HKD2_k127_1381548_11 gag-polyprotein putative aspartyl protease - - - 0.0001287 54.0
HKD2_k127_1381548_12 - - - - 0.0004981 44.0
HKD2_k127_1381548_2 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 436.0
HKD2_k127_1381548_3 ATPases associated with a variety of cellular activities K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 380.0
HKD2_k127_1381548_4 PFAM Amino acid K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 329.0
HKD2_k127_1381548_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000346 212.0
HKD2_k127_1381548_6 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000002411 187.0
HKD2_k127_1381548_7 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000002467 186.0
HKD2_k127_1381548_8 - - - - 0.0000000000000000000000000000000000000000000000773 173.0
HKD2_k127_1381548_9 CAAX protease self-immunity K07052 - - 0.0000000000000000000001528 97.0
HKD2_k127_1394863_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1405.0
HKD2_k127_1394863_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 540.0
HKD2_k127_1394863_10 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
HKD2_k127_1394863_12 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000002899 209.0
HKD2_k127_1394863_13 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001018 205.0
HKD2_k127_1394863_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000002727 116.0
HKD2_k127_1394863_15 Carbohydrate-selective porin, OprB family K16080 - - 0.000000000000000000001045 99.0
HKD2_k127_1394863_16 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000007952 100.0
HKD2_k127_1394863_18 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 - - 0.000001799 60.0
HKD2_k127_1394863_19 Carbohydrate-selective porin, OprB family K16079,K16080 - - 0.00001179 52.0
HKD2_k127_1394863_2 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 466.0
HKD2_k127_1394863_20 FecR protein - - - 0.0005313 51.0
HKD2_k127_1394863_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 360.0
HKD2_k127_1394863_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 322.0
HKD2_k127_1394863_5 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 310.0
HKD2_k127_1394863_6 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 294.0
HKD2_k127_1394863_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003636 286.0
HKD2_k127_1394863_8 Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004856 279.0
HKD2_k127_1394863_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002376 254.0
HKD2_k127_1432564_0 DEAD/H associated K03724 - - 0.0 1364.0
HKD2_k127_1432564_1 Mur ligase middle domain protein K02558 - 6.3.2.45 2.179e-204 645.0
HKD2_k127_1432564_2 B3/4 domain K01890 - 6.1.1.20 1.193e-203 660.0
HKD2_k127_1432564_3 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 545.0
HKD2_k127_1432564_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 458.0
HKD2_k127_1432564_5 CHASE2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 388.0
HKD2_k127_1432564_6 Bacterial type II/III secretion system short domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003314 289.0
HKD2_k127_1432564_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000004326 173.0
HKD2_k127_1432564_8 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000001769 140.0
HKD2_k127_1432564_9 - - - - 0.0000000000000000000002763 102.0
HKD2_k127_1455037_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 3.535e-255 814.0
HKD2_k127_1455037_1 Bacterial protein of unknown function (DUF885) - - - 5.206e-203 649.0
HKD2_k127_1455037_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000006615 192.0
HKD2_k127_1455037_11 QueF-like protein K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000001943 176.0
HKD2_k127_1455037_13 Cupin superfamily (DUF985) K09705 - - 0.0000000002762 61.0
HKD2_k127_1455037_14 Domain of unknown function (DUF4115) K15539 - - 0.00000004249 64.0
HKD2_k127_1455037_2 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 497.0
HKD2_k127_1455037_3 transmembrane transporter activity K13021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 399.0
HKD2_k127_1455037_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 394.0
HKD2_k127_1455037_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001766 259.0
HKD2_k127_1455037_6 Beta-lactamase K01256,K17836 - 3.4.11.2,3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000286 263.0
HKD2_k127_1455037_7 gamma-glutamyl-gamma-aminobutyrate hydrolase activity K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000001886 237.0
HKD2_k127_1455037_8 Cupin superfamily (DUF985) - - - 0.00000000000000000000000000000000000000000000000000000000001333 209.0
HKD2_k127_1455037_9 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000003509 209.0
HKD2_k127_1539533_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1044.0
HKD2_k127_1539533_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 537.0
HKD2_k127_1539533_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 312.0
HKD2_k127_1539533_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 299.0
HKD2_k127_1539533_12 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
HKD2_k127_1539533_13 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002672 265.0
HKD2_k127_1539533_15 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000001026 236.0
HKD2_k127_1539533_16 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000001363 236.0
HKD2_k127_1539533_17 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000005393 173.0
HKD2_k127_1539533_18 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000008083 169.0
HKD2_k127_1539533_19 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000001033 168.0
HKD2_k127_1539533_2 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 532.0
HKD2_k127_1539533_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002274 156.0
HKD2_k127_1539533_22 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000009566 139.0
HKD2_k127_1539533_23 Protein of unknown function (DUF3667) - - - 0.00000000000000000000000000001589 132.0
HKD2_k127_1539533_24 PFAM transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000001483 108.0
HKD2_k127_1539533_25 - - - - 0.00000000000000000000003074 107.0
HKD2_k127_1539533_27 Mitochondrial biogenesis AIM24 - - - 0.0005435 52.0
HKD2_k127_1539533_3 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 449.0
HKD2_k127_1539533_4 DNA recombination protein RmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 389.0
HKD2_k127_1539533_5 5'-3' exonuclease K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 364.0
HKD2_k127_1539533_6 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008712,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016853,GO:0016854,GO:0016857,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901576,GO:1903509 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 349.0
HKD2_k127_1539533_7 Involved in the tonB-independent uptake of proteins K03641,K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 342.0
HKD2_k127_1539533_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 341.0
HKD2_k127_1539533_9 TonB dependent receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 338.0
HKD2_k127_1543918_0 with chaperone activity ATP-binding K03696 - - 1.43e-322 1006.0
HKD2_k127_1543918_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.816e-302 937.0
HKD2_k127_1543918_10 Cupin 2, conserved barrel domain protein - - - 0.000000000000611 76.0
HKD2_k127_1543918_11 Putative peptidoglycan binding domain - - - 0.000000009311 66.0
HKD2_k127_1543918_12 - - - - 0.0000007653 56.0
HKD2_k127_1543918_2 Aminotransferase class-III K00819 - 2.6.1.13 1.975e-206 653.0
HKD2_k127_1543918_3 Protein-arginine kinase K19405 - 2.7.14.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 524.0
HKD2_k127_1543918_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 442.0
HKD2_k127_1543918_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 410.0
HKD2_k127_1543918_6 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 404.0
HKD2_k127_1543918_7 Part of the ABC transporter complex LolCDE involved in the translocation of K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 324.0
HKD2_k127_1543918_8 PFAM UvrB UvrC protein K19411 - - 0.000000000000000000000000000000000000000000000000000000000000000007324 228.0
HKD2_k127_1543918_9 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000009288 209.0
HKD2_k127_1561737_0 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 511.0
HKD2_k127_1561737_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 473.0
HKD2_k127_1561737_2 - - - - 0.000000001141 67.0
HKD2_k127_157092_0 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 3.994e-203 644.0
HKD2_k127_157092_1 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 603.0
HKD2_k127_157092_2 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 498.0
HKD2_k127_157092_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000002816 203.0
HKD2_k127_157092_4 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000005273 166.0
HKD2_k127_157092_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000008308 87.0
HKD2_k127_157092_7 Psort location CytoplasmicMembrane, score - - - 0.0000000000003874 78.0
HKD2_k127_157693_0 Heat shock 70 kDa protein K04043 - - 0.0 1078.0
HKD2_k127_157693_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.606e-287 888.0
HKD2_k127_157693_10 DNA methylase - - - 0.00000000000000000000000000000000000000000004564 165.0
HKD2_k127_157693_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000003921 153.0
HKD2_k127_157693_12 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000000000009592 124.0
HKD2_k127_157693_13 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000009225 109.0
HKD2_k127_157693_14 Metallo-beta-lactamase superfamily - - - 0.00000000000000000002172 94.0
HKD2_k127_157693_16 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00073 44.0
HKD2_k127_157693_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.665e-245 777.0
HKD2_k127_157693_3 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 520.0
HKD2_k127_157693_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 429.0
HKD2_k127_157693_5 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 414.0
HKD2_k127_157693_6 8-oxoguanine DNA glycosylase, N-terminal domain K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 349.0
HKD2_k127_157693_7 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000003361 227.0
HKD2_k127_157693_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000001296 212.0
HKD2_k127_157693_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000002754 170.0
HKD2_k127_1579125_0 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 576.0
HKD2_k127_1579125_1 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 494.0
HKD2_k127_1579125_2 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000003372 254.0
HKD2_k127_1579125_3 DoxX - - - 0.00000000000000000000001626 101.0
HKD2_k127_1581824_0 transporter - - - 5.39e-282 882.0
HKD2_k127_1581824_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.773e-226 706.0
HKD2_k127_1581824_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000004205 167.0
HKD2_k127_1581824_11 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000004468 137.0
HKD2_k127_1581824_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 491.0
HKD2_k127_1581824_3 Competence-damaged protein K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 430.0
HKD2_k127_1581824_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 381.0
HKD2_k127_1581824_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 329.0
HKD2_k127_1581824_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 290.0
HKD2_k127_1581824_7 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001674 260.0
HKD2_k127_1581824_8 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008533 253.0
HKD2_k127_1581824_9 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001975 226.0
HKD2_k127_1632842_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 360.0
HKD2_k127_1632842_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
HKD2_k127_1632842_2 Glycerate kinase family - - - 0.000000000000000000000000000000000000000000000000000008276 198.0
HKD2_k127_164552_0 PFAM carbon starvation protein CstA K06200 - - 1.296e-261 822.0
HKD2_k127_164552_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.544e-202 648.0
HKD2_k127_164552_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 541.0
HKD2_k127_164552_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000125 187.0
HKD2_k127_164552_4 - - - - 0.00000000000000000000002939 108.0
HKD2_k127_165222_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 617.0
HKD2_k127_165222_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 312.0
HKD2_k127_165222_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06951 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001982 277.0
HKD2_k127_165222_3 cellulase activity - - - 0.00000000000000000000000000000000000000000000000003488 192.0
HKD2_k127_165222_4 Glutaredoxin - - - 0.000000000000000000000000000000000000000000002931 166.0
HKD2_k127_165222_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000002254 153.0
HKD2_k127_165222_6 membrane K00389 - - 0.000000000000000003093 89.0
HKD2_k127_165222_7 L,D-transpeptidase catalytic domain - - - 0.00001288 48.0
HKD2_k127_166995_0 Natural resistance-associated macrophage protein K03322 - - 1.694e-209 659.0
HKD2_k127_166995_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 284.0
HKD2_k127_166995_2 Helix-turn-helix diphteria tox regulatory element K11924 - - 0.0000000000000000000000000000000000000000000000000000000000006544 213.0
HKD2_k127_166995_3 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000004582 212.0
HKD2_k127_1690420_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 537.0
HKD2_k127_1690420_1 oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 523.0
HKD2_k127_1690420_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000007746 208.0
HKD2_k127_1690420_11 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000005241 204.0
HKD2_k127_1690420_12 - - - - 0.000000000000000000000000000000000000000000001553 169.0
HKD2_k127_1690420_13 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.00000000000000000000000000000000000022 147.0
HKD2_k127_1690420_14 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000001696 107.0
HKD2_k127_1690420_15 - - - - 0.000000000000009139 81.0
HKD2_k127_1690420_16 PFAM S23 ribosomal protein - - - 0.00000000000006612 76.0
HKD2_k127_1690420_17 Glucose / Sorbosone dehydrogenase - - - 0.000000000002084 67.0
HKD2_k127_1690420_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 509.0
HKD2_k127_1690420_3 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 489.0
HKD2_k127_1690420_4 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 469.0
HKD2_k127_1690420_5 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 451.0
HKD2_k127_1690420_6 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 458.0
HKD2_k127_1690420_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 428.0
HKD2_k127_1690420_8 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 355.0
HKD2_k127_1690420_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 324.0
HKD2_k127_17008_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 503.0
HKD2_k127_17008_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000003336 187.0
HKD2_k127_17008_2 - - - - 0.0000000000000000000001305 101.0
HKD2_k127_17008_3 - - - - 0.0000001116 53.0
HKD2_k127_1702412_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 559.0
HKD2_k127_1702412_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 342.0
HKD2_k127_1702412_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 288.0
HKD2_k127_1702412_3 MMPL family K07003 - - 0.00000000000000000000000000007726 129.0
HKD2_k127_171238_0 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 487.0
HKD2_k127_171238_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 399.0
HKD2_k127_171238_2 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000001846 148.0
HKD2_k127_171238_3 Pfam:UPF0118 - - - 0.00000000000000000000000006807 122.0
HKD2_k127_171238_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000282 103.0
HKD2_k127_171238_5 SnoaL-like domain - - - 0.000000000000000008215 89.0
HKD2_k127_1719743_0 TIGRFAM FeS assembly protein SufB K09014 - - 3.077e-268 829.0
HKD2_k127_1719743_1 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 502.0
HKD2_k127_1719743_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 346.0
HKD2_k127_1737342_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 371.0
HKD2_k127_1737342_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008289 255.0
HKD2_k127_1737342_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000004527 156.0
HKD2_k127_1804373_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.4e-322 996.0
HKD2_k127_1804373_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 5.024e-203 653.0
HKD2_k127_1804373_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 318.0
HKD2_k127_1804373_11 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 308.0
HKD2_k127_1804373_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 299.0
HKD2_k127_1804373_13 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 308.0
HKD2_k127_1804373_14 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 286.0
HKD2_k127_1804373_15 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 282.0
HKD2_k127_1804373_16 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003745 235.0
HKD2_k127_1804373_17 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000009856 217.0
HKD2_k127_1804373_18 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000009958 213.0
HKD2_k127_1804373_19 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000001431 211.0
HKD2_k127_1804373_2 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 582.0
HKD2_k127_1804373_20 Chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000002083 233.0
HKD2_k127_1804373_21 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000111 211.0
HKD2_k127_1804373_22 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000000000000000002025 201.0
HKD2_k127_1804373_23 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000006411 199.0
HKD2_k127_1804373_24 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000001011 162.0
HKD2_k127_1804373_25 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000006795 166.0
HKD2_k127_1804373_26 Biotin/lipoate A/B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000003239 162.0
HKD2_k127_1804373_27 phosphorelay sensor kinase activity K03406,K07675,K13598 - 2.7.13.3 0.000000000000000000000000000000000001039 151.0
HKD2_k127_1804373_28 - - - - 0.000000000000000000000000000000000001759 144.0
HKD2_k127_1804373_29 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000006429 120.0
HKD2_k127_1804373_3 AAA ATPase central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 465.0
HKD2_k127_1804373_30 Protein conserved in bacteria K20920 - - 0.00000000000000000000000007735 123.0
HKD2_k127_1804373_31 O-antigen ligase like membrane protein - - - 0.00000000000000000000001506 115.0
HKD2_k127_1804373_32 AMP binding K06149 - - 0.0000000000000000000002056 104.0
HKD2_k127_1804373_33 ThiS family K03636 - - 0.000000000001521 71.0
HKD2_k127_1804373_4 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 425.0
HKD2_k127_1804373_5 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 413.0
HKD2_k127_1804373_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 357.0
HKD2_k127_1804373_7 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 347.0
HKD2_k127_1804373_8 Competence protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 366.0
HKD2_k127_1804373_9 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 345.0
HKD2_k127_1814703_0 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 477.0
HKD2_k127_1814703_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 447.0
HKD2_k127_1814703_2 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 363.0
HKD2_k127_1814703_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000001043 194.0
HKD2_k127_1814703_4 Domain of unknown function (DUF892) - - - 0.000000000000000000000000000000000000000000000002751 182.0
HKD2_k127_1814703_5 COG1796 DNA polymerase IV (family X) K02347 - - 0.00000000000000000000000000000000000000000000005525 183.0
HKD2_k127_1814703_7 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000004381 98.0
HKD2_k127_1814703_8 UPF0391 membrane protein - - - 0.000000000000002197 76.0
HKD2_k127_1814703_9 - - - - 0.00000000005533 64.0
HKD2_k127_1852214_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 612.0
HKD2_k127_1852214_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005019 267.0
HKD2_k127_1852214_2 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
HKD2_k127_1852214_3 FMN reductase (NADPH) activity K00299,K16902 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006790,GO:0006805,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008752,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009111,GO:0009267,GO:0009308,GO:0009310,GO:0009410,GO:0009605,GO:0009970,GO:0009987,GO:0009991,GO:0010181,GO:0016043,GO:0016054,GO:0016491,GO:0016645,GO:0016646,GO:0019439,GO:0019694,GO:0019752,GO:0022607,GO:0031667,GO:0031668,GO:0031669,GO:0032553,GO:0032787,GO:0033554,GO:0034641,GO:0036094,GO:0042178,GO:0042221,GO:0042365,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0042594,GO:0043167,GO:0043168,GO:0043420,GO:0043421,GO:0043436,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046218,GO:0046306,GO:0046395,GO:0046483,GO:0046700,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051716,GO:0052873,GO:0055114,GO:0065003,GO:0070887,GO:0071466,GO:0071496,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.1.38,1.5.1.45 0.00000000000000000000000000000000000000000000000000002423 192.0
HKD2_k127_1852214_4 - - - - 0.000000000000000000000000000000177 128.0
HKD2_k127_1852214_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000004839 113.0
HKD2_k127_1890434_0 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 580.0
HKD2_k127_1890434_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 476.0
HKD2_k127_1890434_10 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.00000000000000000000000000000000004891 138.0
HKD2_k127_1890434_11 Universal stress protein family - - - 0.0000000000000000000000000000000001646 145.0
HKD2_k127_1890434_12 Ribosomal L32p protein family K02911 - - 0.000000000000000000002363 94.0
HKD2_k127_1890434_13 - - - - 0.00000000000000007174 89.0
HKD2_k127_1890434_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 451.0
HKD2_k127_1890434_3 2-dehydro-3-deoxyphosphooctonate aldolase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 398.0
HKD2_k127_1890434_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 376.0
HKD2_k127_1890434_5 PFAM ABC transporter related K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 343.0
HKD2_k127_1890434_6 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 307.0
HKD2_k127_1890434_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000002626 236.0
HKD2_k127_1890434_8 Cupin - - - 0.000000000000000000000000000000000000000000000000000000002512 207.0
HKD2_k127_1890434_9 Integral membrane protein (intg_mem_TP0381) - - - 0.000000000000000000000000000000000002708 148.0
HKD2_k127_1974214_0 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 435.0
HKD2_k127_1974214_1 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003104 286.0
HKD2_k127_1974214_2 ABC 3 transport family K02075,K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001594 260.0
HKD2_k127_1981177_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1127.0
HKD2_k127_1981177_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1108.0
HKD2_k127_1981177_10 L-lactate dehydrogenase K00101,K16422 - 1.1.2.3,1.1.3.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 498.0
HKD2_k127_1981177_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 436.0
HKD2_k127_1981177_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 430.0
HKD2_k127_1981177_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 439.0
HKD2_k127_1981177_14 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 398.0
HKD2_k127_1981177_15 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 379.0
HKD2_k127_1981177_16 MOSC domain containing protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 334.0
HKD2_k127_1981177_17 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 345.0
HKD2_k127_1981177_18 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
HKD2_k127_1981177_19 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 301.0
HKD2_k127_1981177_2 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1049.0
HKD2_k127_1981177_20 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003391 253.0
HKD2_k127_1981177_21 Carbonic anhydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HKD2_k127_1981177_22 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000186 205.0
HKD2_k127_1981177_23 - - - - 0.0000000000000000000000000000000000000000000000000000004072 196.0
HKD2_k127_1981177_24 PFAM Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000001779 201.0
HKD2_k127_1981177_25 Belongs to the P(II) protein family - - - 0.00000000000000000000000000000000000000000000000000009232 188.0
HKD2_k127_1981177_26 R3H domain - - - 0.000000000000000000000000000000000000000000000000008257 192.0
HKD2_k127_1981177_27 Uncharacterized ACR, COG1678 K07735 - - 0.000000000000000000000000000000000000000000000005685 179.0
HKD2_k127_1981177_28 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000003438 173.0
HKD2_k127_1981177_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.317e-234 734.0
HKD2_k127_1981177_30 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000000000000000000000000005251 147.0
HKD2_k127_1981177_31 major outer membrane lipoprotein - - - 0.000000000000000000000000004993 119.0
HKD2_k127_1981177_32 SAM-dependent methyltransferase - - - 0.000000000000000000000000005579 116.0
HKD2_k127_1981177_33 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000007349 109.0
HKD2_k127_1981177_34 Domain of unknown function (DUF4203) - - - 0.00000000000000000000000009866 113.0
HKD2_k127_1981177_35 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000003867 110.0
HKD2_k127_1981177_37 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000003284 100.0
HKD2_k127_1981177_38 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000005085 96.0
HKD2_k127_1981177_39 TPR repeat - - - 0.00000000000000000002953 96.0
HKD2_k127_1981177_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.213e-221 695.0
HKD2_k127_1981177_41 Protein of unknown function (DUF4230) - - - 0.00000000000004372 81.0
HKD2_k127_1981177_42 - - - - 0.000000005482 62.0
HKD2_k127_1981177_44 - - - - 0.0001239 53.0
HKD2_k127_1981177_45 (SAM)-dependent - - - 0.0006046 45.0
HKD2_k127_1981177_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 9.165e-220 688.0
HKD2_k127_1981177_6 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 3.185e-203 642.0
HKD2_k127_1981177_7 AI-2E family transporter - - - 6.539e-195 635.0
HKD2_k127_1981177_8 Alanine dehydrogenase/PNT, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 525.0
HKD2_k127_1981177_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 517.0
HKD2_k127_2023358_0 arginine decarboxylase K01585 - 4.1.1.19 2.999e-300 932.0
HKD2_k127_2023358_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.3e-295 913.0
HKD2_k127_2023358_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 431.0
HKD2_k127_2023358_11 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
HKD2_k127_2023358_12 organic acid phosphorylation K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000002814 171.0
HKD2_k127_2023358_13 cell redox homeostasis - - - 0.000000000000000000000000000000000000001498 153.0
HKD2_k127_2023358_14 TIGRFAM phosphocarrier, HPr family K11189 - - 0.00000000000000000000000000000000003519 136.0
HKD2_k127_2023358_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000002701 148.0
HKD2_k127_2023358_16 Hydrolases of the alpha beta superfamily K06889 - - 0.0000003765 61.0
HKD2_k127_2023358_2 Asparaginyl-tRNA synthetase K01893 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 5.699e-246 765.0
HKD2_k127_2023358_3 cysteine synthase K01697 - 4.2.1.22 6.705e-205 647.0
HKD2_k127_2023358_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.517e-194 616.0
HKD2_k127_2023358_5 PQQ-like domain K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 603.0
HKD2_k127_2023358_6 cystathionine K01739,K01758 - 2.5.1.48,4.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 580.0
HKD2_k127_2023358_7 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 562.0
HKD2_k127_2023358_8 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 520.0
HKD2_k127_2023358_9 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 426.0
HKD2_k127_2058618_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 400.0
HKD2_k127_2058618_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 301.0
HKD2_k127_2058618_2 ATPases associated with a variety of cellular activities K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003931 268.0
HKD2_k127_2058618_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000001012 176.0
HKD2_k127_2058618_4 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000008679 136.0
HKD2_k127_2058618_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000002042 133.0
HKD2_k127_2058618_6 Glycosyl transferases group 1 - - - 0.0000000000000005864 80.0
HKD2_k127_2058618_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000002092 89.0
HKD2_k127_2058618_8 Major Facilitator - - - 0.00002409 48.0
HKD2_k127_2070000_0 Lipase maturation factor - - - 0.000000000000000000000000000000002786 130.0
HKD2_k127_2070000_1 Lipase maturation factor - - - 0.00000000000000000000000000000001069 138.0
HKD2_k127_2070000_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000001233 106.0
HKD2_k127_2070000_3 Phosphoglycerate mutase family - - - 0.000000000000000000000176 103.0
HKD2_k127_2070000_4 gluconolactonase activity - - - 0.0000000000000000008072 93.0
HKD2_k127_2070000_5 Domain of unknown function (DUF4440) - - - 0.0000000000738 68.0
HKD2_k127_2070000_6 - - - - 0.0000000002545 68.0
HKD2_k127_2070000_7 Protein of unknown function (DUF1697) - - - 0.000001192 57.0
HKD2_k127_207185_0 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 518.0
HKD2_k127_207185_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 301.0
HKD2_k127_207185_2 Methyltransferase fkbm family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 302.0
HKD2_k127_207185_3 Transposase IS200 like K07491 - - 0.000000000000000000002379 98.0
HKD2_k127_2077275_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 463.0
HKD2_k127_2077275_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 451.0
HKD2_k127_2077275_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 438.0
HKD2_k127_2077275_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 345.0
HKD2_k127_2077275_4 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000008553 263.0
HKD2_k127_2077275_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000004922 248.0
HKD2_k127_2077275_6 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000009142 196.0
HKD2_k127_2077275_7 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000004831 124.0
HKD2_k127_214555_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.895e-216 693.0
HKD2_k127_214555_1 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 370.0
HKD2_k127_214555_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000005612 100.0
HKD2_k127_219298_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 371.0
HKD2_k127_219298_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 299.0
HKD2_k127_219298_2 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000001404 215.0
HKD2_k127_219298_3 bacterial-type flagellum organization K02282,K04562 - - 0.000000000000000000000000000000000000000000000000001952 196.0
HKD2_k127_219298_4 - - - - 0.00000000000000000000000000000000000000000000006224 191.0
HKD2_k127_219298_5 Ubiquinone biosynthesis methyltransferase UbiE K07755 - 2.1.1.137 0.0000000000000003033 87.0
HKD2_k127_222009_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 462.0
HKD2_k127_22397_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 388.0
HKD2_k127_22397_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 372.0
HKD2_k127_22397_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 351.0
HKD2_k127_22397_3 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000000000007048 202.0
HKD2_k127_22397_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001154 66.0
HKD2_k127_2293947_0 competence protein COMEC K02238 - - 1.372e-248 775.0
HKD2_k127_2293947_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 382.0
HKD2_k127_2293947_2 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000002175 168.0
HKD2_k127_2293947_3 alpha beta - - - 0.00000000000000000000006312 113.0
HKD2_k127_2293947_4 Putative peptidoglycan binding domain - - - 0.0000009177 61.0
HKD2_k127_235451_0 Alpha-2-Macroglobulin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 321.0
HKD2_k127_235451_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002748 283.0
HKD2_k127_235451_2 surface antigen - - - 0.00000000001304 76.0
HKD2_k127_235451_3 PFAM Protein kinase domain - - - 0.000000006629 68.0
HKD2_k127_237407_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
HKD2_k127_237407_1 competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009951 246.0
HKD2_k127_237407_2 CAAX protease self-immunity - - - 0.00000000000000000000000000003452 129.0
HKD2_k127_237407_4 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000007112 48.0
HKD2_k127_2442704_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 590.0
HKD2_k127_2442704_1 cAMP biosynthetic process K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 435.0
HKD2_k127_2442704_2 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001036 305.0
HKD2_k127_2442704_3 Sigma-70 region 2 - - - 0.000000000000000000000000000000000000000000000000001205 191.0
HKD2_k127_2442704_4 - - - - 0.0000000000000000000000000002289 123.0
HKD2_k127_2442704_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000004751 74.0
HKD2_k127_2442704_6 Tetratricopeptide repeat - - - 0.000000001766 68.0
HKD2_k127_2442704_7 Trypsin - - - 0.00000006457 64.0
HKD2_k127_2442704_8 - - - - 0.000001487 57.0
HKD2_k127_2510597_0 PUA-like domain K00958 - 2.7.7.4 4.816e-249 782.0
HKD2_k127_2510597_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 2.522e-231 722.0
HKD2_k127_2510597_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 404.0
HKD2_k127_2510597_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 385.0
HKD2_k127_2510597_12 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 325.0
HKD2_k127_2510597_13 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 319.0
HKD2_k127_2510597_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 297.0
HKD2_k127_2510597_15 pfam abc K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 302.0
HKD2_k127_2510597_16 Ku70/Ku80 beta-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 295.0
HKD2_k127_2510597_17 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
HKD2_k127_2510597_18 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004498 281.0
HKD2_k127_2510597_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002296 240.0
HKD2_k127_2510597_2 7TM receptor with intracellular HD hydrolase K07037 - - 6.151e-201 640.0
HKD2_k127_2510597_20 Helix-turn-helix diphteria tox regulatory element - - - 0.000000000000000000000000000000000000000000000000000000000219 206.0
HKD2_k127_2510597_21 - - - - 0.00000000000000000000000000000000000000000000000000075 188.0
HKD2_k127_2510597_22 - - - - 0.0000000000000000000000000000000000000000000000001424 186.0
HKD2_k127_2510597_23 Universal stress protein family - - - 0.000000000000000000000000000000000000000002489 162.0
HKD2_k127_2510597_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000001345 134.0
HKD2_k127_2510597_25 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000001 117.0
HKD2_k127_2510597_26 Phosphopantetheine attachment site - - - 0.0000000000000000000000000007803 119.0
HKD2_k127_2510597_27 - - - - 0.000000000000000002544 92.0
HKD2_k127_2510597_28 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000005271 83.0
HKD2_k127_2510597_3 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 568.0
HKD2_k127_2510597_4 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 556.0
HKD2_k127_2510597_5 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 524.0
HKD2_k127_2510597_6 glycine betaine transport K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 528.0
HKD2_k127_2510597_7 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 473.0
HKD2_k127_2510597_8 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 446.0
HKD2_k127_2510597_9 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 427.0
HKD2_k127_2568806_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 580.0
HKD2_k127_2568806_1 glutamate-cysteine ligase activity K06048 GO:0003674,GO:0003824,GO:0016874,GO:0016879 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 491.0
HKD2_k127_2568806_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 333.0
HKD2_k127_2568806_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 289.0
HKD2_k127_2568806_12 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000233 292.0
HKD2_k127_2568806_13 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001889 278.0
HKD2_k127_2568806_14 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
HKD2_k127_2568806_15 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000339 278.0
HKD2_k127_2568806_16 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000001899 261.0
HKD2_k127_2568806_17 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 266.0
HKD2_k127_2568806_18 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009081 244.0
HKD2_k127_2568806_19 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000002113 246.0
HKD2_k127_2568806_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 483.0
HKD2_k127_2568806_20 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000001574 213.0
HKD2_k127_2568806_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000003385 199.0
HKD2_k127_2568806_22 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000436 167.0
HKD2_k127_2568806_23 Transcriptional regulator - - - 0.000000000000000000000000000000000000000002216 160.0
HKD2_k127_2568806_24 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000000000000000003062 146.0
HKD2_k127_2568806_25 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000000000004246 145.0
HKD2_k127_2568806_28 AMP binding - - - 0.0000000000000000000000003572 118.0
HKD2_k127_2568806_29 Sulfotransferase domain - - - 0.0000001777 56.0
HKD2_k127_2568806_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 477.0
HKD2_k127_2568806_31 Sulfotransferase domain - - - 0.0001623 49.0
HKD2_k127_2568806_4 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 464.0
HKD2_k127_2568806_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 428.0
HKD2_k127_2568806_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 415.0
HKD2_k127_2568806_7 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 416.0
HKD2_k127_2568806_8 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 389.0
HKD2_k127_2568806_9 geranylgeranyl reductase activity K21401 - 1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
HKD2_k127_2617371_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 3.18e-320 992.0
HKD2_k127_2617371_1 amino acid peptide transporter K03305,K06218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 591.0
HKD2_k127_2617371_10 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000002689 175.0
HKD2_k127_2617371_12 - - - - 0.0000000000000000000000000000000000001541 148.0
HKD2_k127_2617371_13 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000001519 127.0
HKD2_k127_2617371_14 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000002441 101.0
HKD2_k127_2617371_15 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000002278 92.0
HKD2_k127_2617371_16 - - - - 0.000000000000000003362 89.0
HKD2_k127_2617371_17 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K04760 - - 0.0000000001738 67.0
HKD2_k127_2617371_18 PFAM RNP-1 like RNA-binding protein - - - 0.000000005706 59.0
HKD2_k127_2617371_19 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00002278 48.0
HKD2_k127_2617371_2 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 402.0
HKD2_k127_2617371_3 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 414.0
HKD2_k127_2617371_4 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001738 277.0
HKD2_k127_2617371_5 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
HKD2_k127_2617371_6 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000001612 228.0
HKD2_k127_2617371_7 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
HKD2_k127_2617371_8 Protein of unknown function (DUF3616) - - - 0.0000000000000000000000000000000000000000000000000000004199 207.0
HKD2_k127_2617371_9 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000003221 179.0
HKD2_k127_2617670_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 454.0
HKD2_k127_2617670_1 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 367.0
HKD2_k127_2617670_2 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 292.0
HKD2_k127_2617670_3 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.00000000000000000000000000000000000000000001639 164.0
HKD2_k127_2617670_4 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000000367 127.0
HKD2_k127_2635880_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 416.0
HKD2_k127_2635880_1 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
HKD2_k127_2635880_2 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 340.0
HKD2_k127_2635880_3 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000001259 237.0
HKD2_k127_2635880_4 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000005641 177.0
HKD2_k127_2635880_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000001625 123.0
HKD2_k127_2667763_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1161.0
HKD2_k127_2667763_1 Poly A polymerase head domain K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 595.0
HKD2_k127_2667763_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 547.0
HKD2_k127_2667763_3 2-oxoglutarate dehydrogenase C-terminal K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 459.0
HKD2_k127_2667763_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000001374 238.0
HKD2_k127_2667763_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000007626 164.0
HKD2_k127_2667763_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000001081 152.0
HKD2_k127_2667763_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000001407 117.0
HKD2_k127_2677816_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 5.129e-243 760.0
HKD2_k127_2677816_1 Erythromycin esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 419.0
HKD2_k127_2677816_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000005509 119.0
HKD2_k127_2677816_11 L,D-transpeptidase catalytic domain - - - 0.000000001181 61.0
HKD2_k127_2677816_12 Protein required for attachment to host cells - - - 0.000005984 53.0
HKD2_k127_2677816_2 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 286.0
HKD2_k127_2677816_3 PFAM Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
HKD2_k127_2677816_4 Uncharacterized conserved protein (DUF2267) - - - 0.0000000000000000000000000000000000001939 148.0
HKD2_k127_2677816_5 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000201 151.0
HKD2_k127_2677816_6 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000002579 148.0
HKD2_k127_2677816_7 - - - - 0.000000000000000000000000000000009114 128.0
HKD2_k127_2677816_8 COG0589 Universal stress protein UspA and related K14055 - - 0.00000000000000000000000000000007237 139.0
HKD2_k127_2677816_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000002514 127.0
HKD2_k127_2704304_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 540.0
HKD2_k127_2704304_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000005207 231.0
HKD2_k127_2704304_2 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000009975 181.0
HKD2_k127_2704304_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000005924 120.0
HKD2_k127_2704304_4 Transposase IS200 like K07491 - - 0.0000000000000000000000003186 111.0
HKD2_k127_2704304_5 Aspartyl protease - - - 0.000001752 61.0
HKD2_k127_2739679_0 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004407 256.0
HKD2_k127_2739679_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000004464 201.0
HKD2_k127_2739679_3 - - - - 0.0000000000000000000000000005107 116.0
HKD2_k127_2739679_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000008215 75.0
HKD2_k127_2739679_5 - - - - 0.000004044 51.0
HKD2_k127_2741468_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1040.0
HKD2_k127_2828022_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 6.31e-244 764.0
HKD2_k127_2828022_1 Phosphopantetheine attachment site K00666 - - 1.259e-216 683.0
HKD2_k127_2840946_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 581.0
HKD2_k127_2840946_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 570.0
HKD2_k127_2840946_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 510.0
HKD2_k127_2840946_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 499.0
HKD2_k127_2840946_4 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 447.0
HKD2_k127_2840946_5 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 412.0
HKD2_k127_2840946_6 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 389.0
HKD2_k127_2840946_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 363.0
HKD2_k127_2840946_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002282 271.0
HKD2_k127_2863147_0 Peptidase S46 - - - 4.73e-255 805.0
HKD2_k127_2863147_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 544.0
HKD2_k127_2863147_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000004005 151.0
HKD2_k127_2863147_11 - - - - 0.000000000000000000000000000000000008151 145.0
HKD2_k127_2863147_12 DoxX - - - 0.0000000000000000000000000000000199 130.0
HKD2_k127_2863147_13 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000006289 120.0
HKD2_k127_2863147_15 - - - - 0.0000000000000003183 90.0
HKD2_k127_2863147_16 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.00000000004249 72.0
HKD2_k127_2863147_2 Ku70/Ku80 beta-barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008066 352.0
HKD2_k127_2863147_3 PFAM beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 346.0
HKD2_k127_2863147_4 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000175 274.0
HKD2_k127_2863147_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000118 267.0
HKD2_k127_2863147_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003201 251.0
HKD2_k127_2863147_7 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000002757 224.0
HKD2_k127_2863147_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000005652 213.0
HKD2_k127_2863147_9 membrane - - - 0.0000000000000000000000000000000000000000000000000000001184 202.0
HKD2_k127_2897091_0 Mur ligase family, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 573.0
HKD2_k127_2897091_1 proteins, homologs of microcin C7 resistance protein MccF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 365.0
HKD2_k127_2897091_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000006068 129.0
HKD2_k127_2901872_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 538.0
HKD2_k127_2901872_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 479.0
HKD2_k127_2901872_10 Protein of unknown function (DUF1353) - - - 0.000000000000000000000000000006073 128.0
HKD2_k127_2901872_12 - - - - 0.00000003292 60.0
HKD2_k127_2901872_13 secreted Zn-dependent protease - - - 0.00003093 54.0
HKD2_k127_2901872_14 - - - - 0.0003282 49.0
HKD2_k127_2901872_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 470.0
HKD2_k127_2901872_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 377.0
HKD2_k127_2901872_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 363.0
HKD2_k127_2901872_5 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002153 264.0
HKD2_k127_2901872_6 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001133 223.0
HKD2_k127_2901872_7 Haemolysin-type calcium-binding repeat - - - 0.00000000000000000000000000000000000000000000000004198 195.0
HKD2_k127_2901872_8 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000001251 174.0
HKD2_k127_2901872_9 - - - - 0.0000000000000000000000000000000000009524 148.0
HKD2_k127_2904319_0 PFAM AMP-dependent synthetase and ligase K05939 - 2.3.1.40,6.2.1.20 5.257e-282 884.0
HKD2_k127_2904319_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.573e-282 880.0
HKD2_k127_2904319_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007658 432.0
HKD2_k127_2904319_11 oxidoreductase FAD NAD(P)-binding domain protein K00380 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 427.0
HKD2_k127_2904319_12 Belongs to the SEDS family K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 418.0
HKD2_k127_2904319_13 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 337.0
HKD2_k127_2904319_14 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 327.0
HKD2_k127_2904319_15 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
HKD2_k127_2904319_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 289.0
HKD2_k127_2904319_17 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 286.0
HKD2_k127_2904319_18 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003704 273.0
HKD2_k127_2904319_19 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009982 261.0
HKD2_k127_2904319_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 4.376e-263 829.0
HKD2_k127_2904319_20 protein domain associated with K03595,K06883,K06946 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007732 254.0
HKD2_k127_2904319_21 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002182 233.0
HKD2_k127_2904319_22 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000976 231.0
HKD2_k127_2904319_23 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000298 221.0
HKD2_k127_2904319_24 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000009081 206.0
HKD2_k127_2904319_25 Domain of unknown function (DUF697) - - - 0.000000000000000000000000000000000000000000000000002674 194.0
HKD2_k127_2904319_26 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000008089 186.0
HKD2_k127_2904319_27 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000004141 179.0
HKD2_k127_2904319_28 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000005032 138.0
HKD2_k127_2904319_29 YCII-related domain K09780 - - 0.00000000000000003218 84.0
HKD2_k127_2904319_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 9.742e-239 754.0
HKD2_k127_2904319_30 PFAM IS1 transposase K07480 - - 0.0000006868 51.0
HKD2_k127_2904319_31 Cupin 2, conserved barrel domain protein - - - 0.00003569 48.0
HKD2_k127_2904319_32 Protein of unknown function (DUF1016) - - - 0.0004742 44.0
HKD2_k127_2904319_4 Lysine-2,3-aminomutase - - - 1.749e-197 625.0
HKD2_k127_2904319_5 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 564.0
HKD2_k127_2904319_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 507.0
HKD2_k127_2904319_7 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 473.0
HKD2_k127_2904319_8 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 467.0
HKD2_k127_2904319_9 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 443.0
HKD2_k127_2920844_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1243.0
HKD2_k127_2920844_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000003405 183.0
HKD2_k127_2920844_2 Transposase IS200 like - - - 0.0000000000000000000000000000000005465 132.0
HKD2_k127_2920844_3 transposase IS200-family protein - - - 0.0003443 44.0
HKD2_k127_2937366_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.404e-204 644.0
HKD2_k127_2937366_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 307.0
HKD2_k127_2937366_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000006467 205.0
HKD2_k127_2975005_0 E1-E2 ATPase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 346.0
HKD2_k127_2975005_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000004724 114.0
HKD2_k127_2975005_2 Transposase IS200 like K07491 - - 0.00000000000008041 72.0
HKD2_k127_2975005_3 Transposase IS200 like K07491 - - 0.00000001073 60.0
HKD2_k127_2983792_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 442.0
HKD2_k127_2983792_1 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 396.0
HKD2_k127_2983792_2 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 368.0
HKD2_k127_2983792_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000164 227.0
HKD2_k127_2983792_4 - - - - 0.000000000000000000000000000000000000000001806 161.0
HKD2_k127_3057144_0 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 454.0
HKD2_k127_3057144_1 Belongs to the TPP enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 447.0
HKD2_k127_3060833_0 MmgE/PrpD family K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 550.0
HKD2_k127_3060833_1 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 526.0
HKD2_k127_3060833_10 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000001112 203.0
HKD2_k127_3060833_11 cellulase activity - - - 0.0000000000000000000000000000000000000000001556 173.0
HKD2_k127_3060833_12 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000614 149.0
HKD2_k127_3060833_13 HemY domain protein - - - 0.000000000000000000000000000000003805 150.0
HKD2_k127_3060833_14 Protein of unknown function (DUF1203) - - - 0.000000000000000000001435 100.0
HKD2_k127_3060833_15 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000000000005396 93.0
HKD2_k127_3060833_16 tail collar domain protein K01406,K21449 - 3.4.24.40 0.00000000000001098 83.0
HKD2_k127_3060833_17 - - - - 0.00000000001309 66.0
HKD2_k127_3060833_18 Protein of unknown function (DUF3761) - - - 0.0000006412 57.0
HKD2_k127_3060833_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 359.0
HKD2_k127_3060833_3 methylisocitrate lyase activity K03417 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 351.0
HKD2_k127_3060833_4 Sodium:dicarboxylate symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 343.0
HKD2_k127_3060833_5 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 317.0
HKD2_k127_3060833_6 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 309.0
HKD2_k127_3060833_7 Beta-lactamase K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 303.0
HKD2_k127_3060833_8 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002137 231.0
HKD2_k127_3060833_9 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000005417 212.0
HKD2_k127_306271_0 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 610.0
HKD2_k127_306271_1 SMART alpha amylase, catalytic sub domain K01176 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 557.0
HKD2_k127_306271_10 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000002991 231.0
HKD2_k127_306271_11 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000002576 201.0
HKD2_k127_306271_12 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000000002877 187.0
HKD2_k127_306271_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000001103 177.0
HKD2_k127_306271_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000004326 173.0
HKD2_k127_306271_15 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000189 147.0
HKD2_k127_306271_16 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000171 147.0
HKD2_k127_306271_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000001066 143.0
HKD2_k127_306271_18 Cache domain - - - 0.00000000000000000000000000000000002251 149.0
HKD2_k127_306271_19 NLI interacting factor-like phosphatase - - - 0.00000000000000000000000000000000003842 142.0
HKD2_k127_306271_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 550.0
HKD2_k127_306271_20 Glyoxalase - - - 0.00000000000000000000000000000002607 131.0
HKD2_k127_306271_21 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000001589 128.0
HKD2_k127_306271_22 - - - - 0.0000000000000000000000000000002126 129.0
HKD2_k127_306271_23 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000001951 122.0
HKD2_k127_306271_25 HD domain - - - 0.000000000000000000000000001338 117.0
HKD2_k127_306271_26 SnoaL-like domain - - - 0.000000000000000000000009413 104.0
HKD2_k127_306271_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 456.0
HKD2_k127_306271_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 411.0
HKD2_k127_306271_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 385.0
HKD2_k127_306271_6 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 315.0
HKD2_k127_306271_8 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001002 235.0
HKD2_k127_306271_9 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000004782 220.0
HKD2_k127_3121580_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1180.0
HKD2_k127_3121580_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 3.466e-259 824.0
HKD2_k127_3121580_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
HKD2_k127_3121580_11 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 300.0
HKD2_k127_3121580_12 protein disulfide oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003539 261.0
HKD2_k127_3121580_13 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001694 246.0
HKD2_k127_3121580_14 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000272 251.0
HKD2_k127_3121580_15 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001879 254.0
HKD2_k127_3121580_16 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000007349 226.0
HKD2_k127_3121580_17 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000001419 216.0
HKD2_k127_3121580_18 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000006182 144.0
HKD2_k127_3121580_19 Transcriptional regulator, MarR K06075 - - 0.00000000000000000000000000000000001651 141.0
HKD2_k127_3121580_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 7.289e-253 799.0
HKD2_k127_3121580_20 (Rhomboid) family K19225 - 3.4.21.105 0.0000000000000000000000000000000001736 145.0
HKD2_k127_3121580_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000403 120.0
HKD2_k127_3121580_22 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000001131 100.0
HKD2_k127_3121580_23 Bacterial protein of unknown function (DUF883) - - - 0.00000000000001358 78.0
HKD2_k127_3121580_26 Tetratricopeptide repeat - - - 0.000003359 57.0
HKD2_k127_3121580_3 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 561.0
HKD2_k127_3121580_4 PFAM type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 512.0
HKD2_k127_3121580_5 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 507.0
HKD2_k127_3121580_6 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 464.0
HKD2_k127_3121580_7 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 475.0
HKD2_k127_3121580_8 Beta-Casp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 441.0
HKD2_k127_3121580_9 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 386.0
HKD2_k127_3174245_0 Cytochrome c - - - 9.622e-236 750.0
HKD2_k127_3174245_1 catalase activity - - - 6.152e-201 632.0
HKD2_k127_3174245_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 529.0
HKD2_k127_3174245_3 iron assimilation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 458.0
HKD2_k127_3174245_4 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 335.0
HKD2_k127_3174245_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000001411 220.0
HKD2_k127_3198220_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 8.739e-215 674.0
HKD2_k127_3198220_1 Anticodon binding domain K01880 - 6.1.1.14 1.094e-194 616.0
HKD2_k127_3198220_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 359.0
HKD2_k127_3198220_3 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
HKD2_k127_3198220_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000005517 265.0
HKD2_k127_3198220_5 response to oxidative stress K04063 - - 0.00000000000000000000000000000000000000000000000000001236 194.0
HKD2_k127_3198220_6 - - - - 0.000000000000000000000003027 103.0
HKD2_k127_3198220_7 YXWGXW repeat (2 copies) - - - 0.0002075 48.0
HKD2_k127_324614_0 glycosyl transferase family 2 - - - 3.755e-216 682.0
HKD2_k127_324614_1 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 473.0
HKD2_k127_324614_10 endonuclease III K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 332.0
HKD2_k127_324614_11 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 308.0
HKD2_k127_324614_12 Flavoprotein K01598 - 4.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000003771 252.0
HKD2_k127_324614_13 Guanylate kinase K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000001437 247.0
HKD2_k127_324614_14 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000002144 194.0
HKD2_k127_324614_15 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000003533 183.0
HKD2_k127_324614_16 - - - - 0.000000000000000000000000000000000000000006869 162.0
HKD2_k127_324614_17 Belongs to the bacterial histone-like protein family K03530,K04764 - - 0.000000000000000000000000000000000000003095 150.0
HKD2_k127_324614_18 PFAM peptidase S16 lon domain protein K01338 - 3.4.21.53 0.0000000000000000000000000000000000001835 153.0
HKD2_k127_324614_19 Protein of unknown function (DUF1232) - - - 0.00000000002168 71.0
HKD2_k127_324614_2 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 404.0
HKD2_k127_324614_20 Binds directly to 16S ribosomal RNA K02968 - - 0.000002722 53.0
HKD2_k127_324614_3 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 398.0
HKD2_k127_324614_4 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 384.0
HKD2_k127_324614_5 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 391.0
HKD2_k127_324614_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03471 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
HKD2_k127_324614_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 350.0
HKD2_k127_324614_8 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 361.0
HKD2_k127_324614_9 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 343.0
HKD2_k127_3264868_0 - - - - 0.000000000000000000000000005248 114.0
HKD2_k127_330320_0 cellulose binding - - - 5.994e-254 812.0
HKD2_k127_330320_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.802e-209 663.0
HKD2_k127_330320_10 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 422.0
HKD2_k127_330320_11 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 365.0
HKD2_k127_330320_12 Glycoside-hydrolase family GH114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 321.0
HKD2_k127_330320_13 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 323.0
HKD2_k127_330320_14 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 299.0
HKD2_k127_330320_15 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000003258 252.0
HKD2_k127_330320_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000002383 220.0
HKD2_k127_330320_17 - - - - 0.000000000000000000000000000000000000000000000000003425 197.0
HKD2_k127_330320_18 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000003098 184.0
HKD2_k127_330320_19 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000001052 180.0
HKD2_k127_330320_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 6.826e-197 627.0
HKD2_k127_330320_20 Lysin motif - - - 0.00000000000000000000000000000000000000000002136 171.0
HKD2_k127_330320_21 - - - - 0.00000000000000000000000000000000000000001291 158.0
HKD2_k127_330320_22 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000001276 163.0
HKD2_k127_330320_23 ACT domain protein - - - 0.0000000000000000000000000000000000000002834 155.0
HKD2_k127_330320_24 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000003692 150.0
HKD2_k127_330320_25 Ami_3 - - - 0.0000000000000000000000000000000000000187 155.0
HKD2_k127_330320_26 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001272 138.0
HKD2_k127_330320_27 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000003652 130.0
HKD2_k127_330320_28 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000009674 106.0
HKD2_k127_330320_29 Putative peptidoglycan binding domain - - - 0.0000000000000000000001072 108.0
HKD2_k127_330320_3 UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 527.0
HKD2_k127_330320_30 cell redox homeostasis - - - 0.0000000000003078 78.0
HKD2_k127_330320_31 Domain of unknown function (DUF4404) - - - 0.000000000001608 74.0
HKD2_k127_330320_32 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K17736 - - 0.00000007001 59.0
HKD2_k127_330320_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 488.0
HKD2_k127_330320_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 469.0
HKD2_k127_330320_6 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 442.0
HKD2_k127_330320_7 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 - 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 438.0
HKD2_k127_330320_8 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 439.0
HKD2_k127_330320_9 PFAM Rieske 2Fe-2S domain protein K00479,K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 417.0
HKD2_k127_334757_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.188e-289 898.0
HKD2_k127_334757_1 Rhodanese domain protein K01069 - 3.1.2.6 1.715e-215 677.0
HKD2_k127_334757_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 392.0
HKD2_k127_334757_3 PFAM Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 384.0
HKD2_k127_334757_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000001359 172.0
HKD2_k127_334757_5 Cupin - - - 0.000000000000003105 81.0
HKD2_k127_3438489_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 3.185e-274 864.0
HKD2_k127_3438489_1 TIGRFAM ribonuclease, Rne Rng family K08301 - - 2.346e-257 801.0
HKD2_k127_3438489_10 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003183 276.0
HKD2_k127_3438489_11 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000143 251.0
HKD2_k127_3438489_12 - - - - 0.0000000000000000000000000000000000000000001115 168.0
HKD2_k127_3438489_13 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000163 101.0
HKD2_k127_3438489_17 Putative peptidoglycan binding domain - - - 0.00001386 53.0
HKD2_k127_3438489_18 thiamine biosynthesis protein ThiS K03154 - - 0.0001461 47.0
HKD2_k127_3438489_2 Type II/IV secretion system protein - - - 8.698e-233 733.0
HKD2_k127_3438489_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 599.0
HKD2_k127_3438489_4 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 560.0
HKD2_k127_3438489_5 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 495.0
HKD2_k127_3438489_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 498.0
HKD2_k127_3438489_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 398.0
HKD2_k127_3438489_8 Bacterial type II/III secretion system short domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 342.0
HKD2_k127_3438489_9 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001459 277.0
HKD2_k127_3460004_0 acetyltransferase - - - 0.0000000000000000000000000000001764 125.0
HKD2_k127_3460004_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000005895 104.0
HKD2_k127_3474779_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 525.0
HKD2_k127_3474779_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 494.0
HKD2_k127_3474779_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002641 271.0
HKD2_k127_3474779_3 P-type ATPase K17686 - 3.6.3.54 0.0000000001683 65.0
HKD2_k127_3501977_0 Sortilin, neurotensin receptor 3, - - - 0.0 1255.0
HKD2_k127_3501977_1 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000003214 248.0
HKD2_k127_3501977_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000003049 171.0
HKD2_k127_3501977_3 SMART metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.00000000000000000000000000000000000002911 145.0
HKD2_k127_3523959_0 Adenylate cyclase - - - 3.515e-194 621.0
HKD2_k127_3523959_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 549.0
HKD2_k127_3523959_10 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000004098 175.0
HKD2_k127_3523959_11 PIN domain - - - 0.000000000000000000000000000000000009293 141.0
HKD2_k127_3523959_12 - - - - 0.0000000000000000000000000000000000762 140.0
HKD2_k127_3523959_13 cAMP biosynthetic process - - - 0.00000000000000000002961 101.0
HKD2_k127_3523959_14 Adenylate cyclase - - - 0.00000000000000005571 89.0
HKD2_k127_3523959_15 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000313 55.0
HKD2_k127_3523959_16 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000105 53.0
HKD2_k127_3523959_2 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 435.0
HKD2_k127_3523959_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 432.0
HKD2_k127_3523959_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 400.0
HKD2_k127_3523959_5 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 397.0
HKD2_k127_3523959_6 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 390.0
HKD2_k127_3523959_7 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 349.0
HKD2_k127_3523959_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000002193 260.0
HKD2_k127_3523959_9 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.000000000000000000000000000000000000000000000000004199 184.0
HKD2_k127_357447_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.836e-241 758.0
HKD2_k127_357447_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 312.0
HKD2_k127_357447_2 Beta-lactamase K01467 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000001515 261.0
HKD2_k127_357447_3 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
HKD2_k127_357447_4 - - - - 0.00000000000000000000000000000000000000004755 156.0
HKD2_k127_357447_5 Redoxin - - - 0.0000000000000000000000000000000000000003206 151.0
HKD2_k127_357447_6 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000007992 119.0
HKD2_k127_357447_8 Hep Hag repeat protein K07278,K21449 - - 0.00000000001397 69.0
HKD2_k127_357447_9 outer membrane autotransporter barrel domain protein - - - 0.00000001028 64.0
HKD2_k127_3577274_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 331.0
HKD2_k127_3605516_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 591.0
HKD2_k127_3605516_1 Preprotein translocase subunit K03210 - - 0.00000000000000000000001846 104.0
HKD2_k127_3650918_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 2.497e-277 885.0
HKD2_k127_3650918_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 520.0
HKD2_k127_3650918_10 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00003934 46.0
HKD2_k127_3650918_11 S-acyltransferase activity K00382,K00627 - 1.8.1.4,2.3.1.12 0.0001668 44.0
HKD2_k127_3650918_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 483.0
HKD2_k127_3650918_3 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 412.0
HKD2_k127_3650918_4 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 403.0
HKD2_k127_3650918_5 von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 387.0
HKD2_k127_3650918_6 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 331.0
HKD2_k127_3650918_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000001756 242.0
HKD2_k127_3650918_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000003663 156.0
HKD2_k127_3650918_9 - - - - 0.00000000000000000000000000000000000001937 149.0
HKD2_k127_379526_0 Sortilin, neurotensin receptor 3, - - - 0.0 1305.0
HKD2_k127_379526_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.244e-276 860.0
HKD2_k127_379526_10 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 517.0
HKD2_k127_379526_11 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 464.0
HKD2_k127_379526_12 lipid A export permease ATP-binding protein MsbA K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 437.0
HKD2_k127_379526_13 Molybdenum Cofactor Synthesis C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 381.0
HKD2_k127_379526_14 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 363.0
HKD2_k127_379526_15 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
HKD2_k127_379526_16 DnaJ molecular chaperone homology domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 345.0
HKD2_k127_379526_17 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 341.0
HKD2_k127_379526_18 Glycosyltransferase Family 4 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 336.0
HKD2_k127_379526_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 326.0
HKD2_k127_379526_2 MacB-like periplasmic core domain - - - 1.225e-261 830.0
HKD2_k127_379526_20 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 312.0
HKD2_k127_379526_21 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 310.0
HKD2_k127_379526_22 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 298.0
HKD2_k127_379526_23 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001121 289.0
HKD2_k127_379526_24 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007371 278.0
HKD2_k127_379526_25 Histidinol phosphatase and related hydrolases of the PHP family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003713 277.0
HKD2_k127_379526_26 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002599 262.0
HKD2_k127_379526_27 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000001578 257.0
HKD2_k127_379526_28 acetyltransferase, isoleucine patch superfamily K03818 GO:0003674,GO:0003824,GO:0008374,GO:0016740,GO:0016746,GO:0016747 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002478 253.0
HKD2_k127_379526_29 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003641 241.0
HKD2_k127_379526_3 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 9.481e-242 760.0
HKD2_k127_379526_30 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000006053 246.0
HKD2_k127_379526_31 PFAM Uracil-DNA glycosylase superfamily K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
HKD2_k127_379526_32 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000002557 226.0
HKD2_k127_379526_34 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000162 221.0
HKD2_k127_379526_35 Tetratricopeptide TPR_2 repeat protein K05807 - - 0.00000000000000000000000000000000000000000000000000000000001017 222.0
HKD2_k127_379526_36 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000611 217.0
HKD2_k127_379526_37 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000008698 205.0
HKD2_k127_379526_38 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000006569 196.0
HKD2_k127_379526_39 MoaC family - - - 0.00000000000000000000000000000000000000000001859 167.0
HKD2_k127_379526_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 5.293e-205 647.0
HKD2_k127_379526_40 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000001594 165.0
HKD2_k127_379526_41 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000002242 161.0
HKD2_k127_379526_42 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000001895 145.0
HKD2_k127_379526_43 Tetratricopeptide repeat - - - 0.000000000000000000000000000000252 134.0
HKD2_k127_379526_44 antisigma factor binding K04749 - - 0.000000000000000000000000000007288 122.0
HKD2_k127_379526_45 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000002249 116.0
HKD2_k127_379526_46 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000009426 112.0
HKD2_k127_379526_47 Intracellular proteinase inhibitor - - - 0.0000000000000000000000004601 112.0
HKD2_k127_379526_48 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000000000002264 102.0
HKD2_k127_379526_5 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 615.0
HKD2_k127_379526_51 23S rRNA-intervening sequence protein - - - 0.0000000000000002905 79.0
HKD2_k127_379526_52 - - - - 0.0000000000000006955 87.0
HKD2_k127_379526_53 MacB-like periplasmic core domain - - - 0.0000000000000008844 82.0
HKD2_k127_379526_54 Protein of unknown function (DUF2905) - - - 0.000000000000007102 77.0
HKD2_k127_379526_55 - - - - 0.00000000000003457 78.0
HKD2_k127_379526_56 23S rRNA-intervening sequence protein - - - 0.0000000000001182 74.0
HKD2_k127_379526_57 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000002848 78.0
HKD2_k127_379526_58 - - - - 0.0000000002711 66.0
HKD2_k127_379526_59 efflux transmembrane transporter activity - - - 0.00000006748 59.0
HKD2_k127_379526_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 622.0
HKD2_k127_379526_60 Glycine-zipper domain - - - 0.000001522 55.0
HKD2_k127_379526_61 efflux transmembrane transporter activity - - - 0.000006558 49.0
HKD2_k127_379526_62 - - - - 0.00002507 46.0
HKD2_k127_379526_7 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 571.0
HKD2_k127_379526_8 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 558.0
HKD2_k127_379526_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 527.0
HKD2_k127_380990_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1432.0
HKD2_k127_380990_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 475.0
HKD2_k127_380990_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000003787 187.0
HKD2_k127_3832575_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.004e-248 778.0
HKD2_k127_3832575_1 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 2.149e-237 751.0
HKD2_k127_3832575_10 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 309.0
HKD2_k127_3832575_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002987 274.0
HKD2_k127_3832575_12 Cobalamin (vitamin B12) biosynthesis CbiX protein - - - 0.00000000000000000000000000000000000000000000000003254 186.0
HKD2_k127_3832575_13 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000001415 164.0
HKD2_k127_3832575_14 transporter - - - 0.000000000000000000000000131 115.0
HKD2_k127_3832575_15 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.0000000000000000000187 97.0
HKD2_k127_3832575_17 - - - - 0.00000122 57.0
HKD2_k127_3832575_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.402e-203 645.0
HKD2_k127_3832575_3 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 599.0
HKD2_k127_3832575_4 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 440.0
HKD2_k127_3832575_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 411.0
HKD2_k127_3832575_6 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 392.0
HKD2_k127_3832575_8 CbiX K03795 - 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 332.0
HKD2_k127_3832575_9 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 317.0
HKD2_k127_3836517_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.127e-196 621.0
HKD2_k127_3836517_1 Male sterility protein K12454 - 5.1.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 526.0
HKD2_k127_3836517_10 nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000007903 176.0
HKD2_k127_3836517_11 dehydratase - - - 0.000000000000000000000000000000001739 134.0
HKD2_k127_3836517_12 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000001653 114.0
HKD2_k127_3836517_14 surface antigen - - - 0.0000000000000002405 88.0
HKD2_k127_3836517_15 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) - - - 0.0000000000000007507 81.0
HKD2_k127_3836517_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 375.0
HKD2_k127_3836517_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 361.0
HKD2_k127_3836517_4 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 311.0
HKD2_k127_3836517_5 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 310.0
HKD2_k127_3836517_6 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 299.0
HKD2_k127_3836517_7 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000027 263.0
HKD2_k127_3836517_8 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
HKD2_k127_3836517_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000003273 191.0
HKD2_k127_3850396_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 5.407e-278 862.0
HKD2_k127_3850396_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 6.821e-203 636.0
HKD2_k127_3850396_2 - - - - 0.0000000000001695 73.0
HKD2_k127_3911312_0 Glutamate formimidoyltransferase K00603,K13990 - 2.1.2.5,4.3.1.4 9.171e-208 660.0
HKD2_k127_3911312_1 urocanate hydratase activity K01712 - 4.2.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 351.0
HKD2_k127_3911312_2 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 294.0
HKD2_k127_3926808_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region - - - 2.192e-282 883.0
HKD2_k127_3926808_1 peptidase activity K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 474.0
HKD2_k127_3926808_10 - - - - 0.0000000000000003988 81.0
HKD2_k127_3926808_11 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.000000001476 61.0
HKD2_k127_3926808_2 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 432.0
HKD2_k127_3926808_3 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 373.0
HKD2_k127_3926808_4 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 342.0
HKD2_k127_3926808_5 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 297.0
HKD2_k127_3926808_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001614 213.0
HKD2_k127_3926808_7 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000005651 209.0
HKD2_k127_3926808_8 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.000000000000000000000000000000000000000000000005187 175.0
HKD2_k127_3926808_9 - - - - 0.0000000000000000000000001616 113.0
HKD2_k127_39371_0 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 345.0
HKD2_k127_39371_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000001126 233.0
HKD2_k127_39371_2 Uncharacterized conserved protein (DUF2267) - - - 0.000000000000000000000000000000000000000000002731 168.0
HKD2_k127_39371_3 - - - - 0.0000000000000000000000000000000000000000003418 158.0
HKD2_k127_39371_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000008366 131.0
HKD2_k127_39371_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000006109 133.0
HKD2_k127_39371_6 SPW repeat - - - 0.0000000000000000006263 89.0
HKD2_k127_39371_9 Nitroreductase family - - - 0.0000001829 55.0
HKD2_k127_3941554_0 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 523.0
HKD2_k127_3941554_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 411.0
HKD2_k127_3941554_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 402.0
HKD2_k127_3941554_3 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 363.0
HKD2_k127_3941554_4 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000006096 271.0
HKD2_k127_3941554_5 Phosphopantetheine attachment site - - - 0.0000000000000000000344 93.0
HKD2_k127_3961475_0 SMART Elongator protein 3 MiaB NifB K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 468.0
HKD2_k127_3961475_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 343.0
HKD2_k127_3961475_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002348 285.0
HKD2_k127_3961475_3 radical SAM domain protein K06138 - - 0.00000000000002026 78.0
HKD2_k127_3978441_0 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 5.154e-217 681.0
HKD2_k127_3978441_1 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 377.0
HKD2_k127_3978441_2 Pseudouridine synthase K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 289.0
HKD2_k127_3978441_3 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000001419 227.0
HKD2_k127_3978441_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000007896 161.0
HKD2_k127_3978441_5 PAP2 superfamily - - - 0.0000000000002158 74.0
HKD2_k127_3989412_0 PFAM CBS domain containing protein K03281 - - 2.848e-212 675.0
HKD2_k127_3989412_1 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 601.0
HKD2_k127_3989412_2 POT family K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000346 255.0
HKD2_k127_3989412_3 - - - - 0.0000000000000000000000000007632 116.0
HKD2_k127_3994929_0 PFAM GlcNAc-PI de-N-acetylase - - - 5.916e-270 857.0
HKD2_k127_3994929_1 spermatogenesis - GO:0000003,GO:0007276,GO:0007283,GO:0008150,GO:0019953,GO:0022414,GO:0032501,GO:0032504,GO:0044703,GO:0048232,GO:0048609,GO:0051704 - 1.085e-247 788.0
HKD2_k127_3994929_10 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007266 271.0
HKD2_k127_3994929_11 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000005368 206.0
HKD2_k127_3994929_13 RES - - - 0.0000000000000000000000000000000000005325 145.0
HKD2_k127_3994929_14 HemY domain protein - - - 0.0000000000000000000000000000000000235 154.0
HKD2_k127_3994929_15 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000000003975 135.0
HKD2_k127_3994929_16 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000002298 141.0
HKD2_k127_3994929_17 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000577 146.0
HKD2_k127_3994929_18 CAAX protease self-immunity - - - 0.000000000000000000000000000000008026 136.0
HKD2_k127_3994929_19 protein histidine kinase activity - - - 0.00000000000000000000000005882 114.0
HKD2_k127_3994929_2 Glycoside hydrolase - - - 1.29e-232 734.0
HKD2_k127_3994929_20 CAAX protease self-immunity - - - 0.00000000000000000000007002 107.0
HKD2_k127_3994929_3 Sodium:solute symporter family - - - 3.28e-205 654.0
HKD2_k127_3994929_4 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 442.0
HKD2_k127_3994929_5 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 396.0
HKD2_k127_3994929_6 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 367.0
HKD2_k127_3994929_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 315.0
HKD2_k127_3994929_8 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 311.0
HKD2_k127_3994929_9 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008313 280.0
HKD2_k127_3999757_0 ABC-2 type transporter - - - 0.0 1113.0
HKD2_k127_3999757_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.319e-226 722.0
HKD2_k127_3999757_10 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 396.0
HKD2_k127_3999757_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 373.0
HKD2_k127_3999757_12 ECF sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 310.0
HKD2_k127_3999757_13 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 301.0
HKD2_k127_3999757_14 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 286.0
HKD2_k127_3999757_15 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
HKD2_k127_3999757_16 Ankyrin repeats (3 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
HKD2_k127_3999757_17 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003333 259.0
HKD2_k127_3999757_18 PFAM Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000001821 243.0
HKD2_k127_3999757_19 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
HKD2_k127_3999757_2 Peptidase family M28 - - - 7.245e-221 704.0
HKD2_k127_3999757_20 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000009186 210.0
HKD2_k127_3999757_21 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000005877 207.0
HKD2_k127_3999757_22 GDYXXLXY protein - - - 0.00000000000000000000000002167 116.0
HKD2_k127_3999757_23 - - - - 0.00000000000000000000002723 100.0
HKD2_k127_3999757_24 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.000000000000000000002762 96.0
HKD2_k127_3999757_25 - - - - 0.000000000000000000004511 94.0
HKD2_k127_3999757_26 Serine Threonine protein kinase K08884 - 2.7.11.1 0.00000000000000000001818 103.0
HKD2_k127_3999757_27 - - - - 0.000000000000000006146 85.0
HKD2_k127_3999757_28 GYD domain - - - 0.00000000000000007992 81.0
HKD2_k127_3999757_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.538e-218 681.0
HKD2_k127_3999757_32 - - - - 0.0000000203 56.0
HKD2_k127_3999757_33 Transporter - - - 0.00000002306 66.0
HKD2_k127_3999757_4 Bacterial protein of unknown function (DUF885) - - - 6.625e-195 625.0
HKD2_k127_3999757_5 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 542.0
HKD2_k127_3999757_6 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 521.0
HKD2_k127_3999757_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 498.0
HKD2_k127_3999757_8 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 431.0
HKD2_k127_3999757_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 386.0
HKD2_k127_4060001_0 Bacterial protein of unknown function (DUF853) - - - 3.61e-203 645.0
HKD2_k127_4060001_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002191 259.0
HKD2_k127_4060001_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000004195 168.0
HKD2_k127_4060001_3 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000001582 123.0
HKD2_k127_4060001_4 - - - - 0.0000000000000000000000001146 109.0
HKD2_k127_4060001_5 Protein of unknown function (DUF1761) - - - 0.000000000000000005225 90.0
HKD2_k127_4060001_6 Thioredoxin K03671 - - 0.000007112 48.0
HKD2_k127_4060001_7 general secretion pathway protein - - - 0.00002173 48.0
HKD2_k127_4073818_0 PFAM peptidase M16 domain protein K07263 - - 5e-324 1013.0
HKD2_k127_4073818_1 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 373.0
HKD2_k127_4073818_11 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000007591 111.0
HKD2_k127_4073818_12 - - - - 0.000000000002058 74.0
HKD2_k127_4073818_13 Mammalian cell entry related domain protein K02067 - - 0.00000000444 68.0
HKD2_k127_4073818_14 Peptidoglycan binding domain - - - 0.000001901 58.0
HKD2_k127_4073818_15 Lytic murein transglycosylase - - - 0.00005417 53.0
HKD2_k127_4073818_2 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 321.0
HKD2_k127_4073818_3 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
HKD2_k127_4073818_4 DEAD DEAH box helicase K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000001912 235.0
HKD2_k127_4073818_5 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000004826 207.0
HKD2_k127_4073818_6 Found in ATP-dependent protease La (LON) - - - 0.000000000000000000000000000000000000000000000000000000207 197.0
HKD2_k127_4073818_7 - - - - 0.00000000000000000000000000000000000000000000000000423 200.0
HKD2_k127_4073818_8 - - - - 0.000000000000000000000000000000000000000005954 159.0
HKD2_k127_4073818_9 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000005028 154.0
HKD2_k127_4076752_0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 6.727e-230 726.0
HKD2_k127_4076752_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 5.576e-210 673.0
HKD2_k127_4076752_10 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 328.0
HKD2_k127_4076752_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003584 280.0
HKD2_k127_4076752_12 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001364 275.0
HKD2_k127_4076752_13 Protein kinase domain K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002882 278.0
HKD2_k127_4076752_14 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000001572 228.0
HKD2_k127_4076752_15 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000008089 191.0
HKD2_k127_4076752_16 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000004536 187.0
HKD2_k127_4076752_17 Domain of unknown function (DUF4347) - - - 0.0000000000000000000000000000000000000000000000002568 203.0
HKD2_k127_4076752_18 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000004301 175.0
HKD2_k127_4076752_19 Yqey-like protein K09117 - - 0.000000000000000000000000000000000001461 143.0
HKD2_k127_4076752_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.941e-209 657.0
HKD2_k127_4076752_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000007721 143.0
HKD2_k127_4076752_21 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000771 126.0
HKD2_k127_4076752_22 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000001477 124.0
HKD2_k127_4076752_23 Conserved repeat domain - - - 0.00000000000000000001288 109.0
HKD2_k127_4076752_24 G8 - - - 0.000002926 61.0
HKD2_k127_4076752_25 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00002902 50.0
HKD2_k127_4076752_3 NADH Ubiquinone plastoquinone (complex I) K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 556.0
HKD2_k127_4076752_4 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 552.0
HKD2_k127_4076752_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 432.0
HKD2_k127_4076752_6 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 379.0
HKD2_k127_4076752_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 382.0
HKD2_k127_4076752_8 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 348.0
HKD2_k127_4076752_9 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
HKD2_k127_4114032_0 alpha amylase catalytic K01182,K05343 - 3.2.1.1,3.2.1.10,5.4.99.16 0.0 1330.0
HKD2_k127_4114032_1 Secretory lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 572.0
HKD2_k127_4114032_10 KTSC domain - - - 0.00000000001467 69.0
HKD2_k127_4114032_2 RecG wedge domain K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 427.0
HKD2_k127_4114032_3 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
HKD2_k127_4114032_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002491 284.0
HKD2_k127_4114032_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - 0.000000000000000000000000000000000000000000000000000001123 200.0
HKD2_k127_4114032_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000002686 183.0
HKD2_k127_4114032_7 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000004865 137.0
HKD2_k127_4114032_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000002374 113.0
HKD2_k127_4148356_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 573.0
HKD2_k127_4148356_1 GHMP kinase domain protein K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 471.0
HKD2_k127_4148356_10 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000002169 213.0
HKD2_k127_4148356_11 Bacterial fructose-1,6-bisphosphatase, glpX-encoded - - - 0.0000000000000000000000000000000000000000000000001547 180.0
HKD2_k127_4148356_12 NHL repeat - - - 0.00000000000000000000000000000000000000000002353 186.0
HKD2_k127_4148356_13 NHL repeat - - - 0.0000000000000000000000000000000000000000008187 179.0
HKD2_k127_4148356_14 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000009978 178.0
HKD2_k127_4148356_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000002719 153.0
HKD2_k127_4148356_17 - - - - 0.000000000000000000000000000000000005856 153.0
HKD2_k127_4148356_18 chaperone-mediated protein folding - - - 0.00000000000000000000002082 117.0
HKD2_k127_4148356_19 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000002746 76.0
HKD2_k127_4148356_2 integrase domain protein SAM domain protein K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 399.0
HKD2_k127_4148356_20 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000135 61.0
HKD2_k127_4148356_3 PFAM Transaldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 316.0
HKD2_k127_4148356_4 PFAM UvrB UvrC protein K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 310.0
HKD2_k127_4148356_5 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
HKD2_k127_4148356_6 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 304.0
HKD2_k127_4148356_9 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000001387 208.0
HKD2_k127_4157270_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.098e-255 790.0
HKD2_k127_4157270_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.128e-245 765.0
HKD2_k127_4157270_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 342.0
HKD2_k127_4157270_3 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007736 330.0
HKD2_k127_4157270_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 325.0
HKD2_k127_4157270_5 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005058 230.0
HKD2_k127_4157270_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000000000000000000000000000000000000000000003197 179.0
HKD2_k127_4157270_7 ATP synthase delta (OSCP) subunit K02113 - - 0.0000000000000000000000000000000000000013 151.0
HKD2_k127_4157270_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000003225 144.0
HKD2_k127_4157270_9 ATP synthase subunit C K02110 - - 0.000000000000000005008 85.0
HKD2_k127_4199826_0 Protein of unknown function (DUF2892) - - - 0.000000000000000000549 89.0
HKD2_k127_4199826_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000004534 57.0
HKD2_k127_4237002_0 Acetyl-coenzyme A synthetase N-terminus - - - 5e-324 1001.0
HKD2_k127_4237002_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 6.639e-284 889.0
HKD2_k127_4237002_10 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000006546 243.0
HKD2_k127_4237002_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000008344 240.0
HKD2_k127_4237002_12 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001889 229.0
HKD2_k127_4237002_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000004991 214.0
HKD2_k127_4237002_14 Methylpurine-DNA glycosylase (MPG) - - - 0.0000000000000000000000000000000000000000000000000000000005919 207.0
HKD2_k127_4237002_15 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000008325 171.0
HKD2_k127_4237002_16 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000009256 159.0
HKD2_k127_4237002_17 - - - - 0.000000000000000000000000000000009853 132.0
HKD2_k127_4237002_18 CutA1 divalent ion tolerance protein - - - 0.000000000000000000000000001205 115.0
HKD2_k127_4237002_2 FAD binding domain - - - 3.728e-244 761.0
HKD2_k127_4237002_20 - - - - 0.00000000000000000000265 97.0
HKD2_k127_4237002_22 energy transducer activity - - - 0.00006702 53.0
HKD2_k127_4237002_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 544.0
HKD2_k127_4237002_4 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 489.0
HKD2_k127_4237002_5 amino acid K20265 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0006873,GO:0006885,GO:0008150,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0019725,GO:0022804,GO:0022857,GO:0030003,GO:0030004,GO:0030641,GO:0031224,GO:0031226,GO:0034220,GO:0042592,GO:0044425,GO:0044459,GO:0044464,GO:0045852,GO:0046942,GO:0046943,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051453,GO:0051454,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:0098771,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 457.0
HKD2_k127_4237002_6 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 378.0
HKD2_k127_4237002_7 Calcineurin-like phosphoesterase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 379.0
HKD2_k127_4237002_8 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 329.0
HKD2_k127_4237002_9 OsmC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000011 235.0
HKD2_k127_4244553_0 ThiC-associated domain K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 311.0
HKD2_k127_4244553_1 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000002262 235.0
HKD2_k127_4272791_0 permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 289.0
HKD2_k127_4272791_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008378,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000003666 143.0
HKD2_k127_4272791_2 PEP-utilising enzyme, TIM barrel domain K01007 - 2.7.9.2 0.000000007267 59.0
HKD2_k127_4272791_3 COG1668 ABC-type Na efflux pump, permease component K01992,K09696 - - 0.00000005744 64.0
HKD2_k127_4274832_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.722e-296 922.0
HKD2_k127_4274832_1 Glycine cleavage T-protein C-terminal barrel domain K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 420.0
HKD2_k127_4274832_10 O-methyltransferase activity - - - 0.0000000000000004759 87.0
HKD2_k127_4274832_11 - - - - 0.0000000001415 69.0
HKD2_k127_4274832_2 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 342.0
HKD2_k127_4274832_3 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 299.0
HKD2_k127_4274832_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000005868 157.0
HKD2_k127_4274832_5 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000001964 152.0
HKD2_k127_4274832_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000009722 98.0
HKD2_k127_4274832_7 chlorophyll binding - - - 0.0000000000000000000029 99.0
HKD2_k127_4274832_9 - - - - 0.00000000000000002187 93.0
HKD2_k127_4362585_0 Male sterility - - - 3.496e-292 910.0
HKD2_k127_4362585_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 568.0
HKD2_k127_4362585_2 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 436.0
HKD2_k127_4362585_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007625 277.0
HKD2_k127_4362585_4 - - - - 0.00000000000000000000000000000000000000000000000000000000003001 213.0
HKD2_k127_4362585_5 granule-associated protein - - - 0.00000000000000000000000000000008613 130.0
HKD2_k127_4362585_6 Belongs to the aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 0.000000000000000000002057 97.0
HKD2_k127_4362585_7 PGAP1-like protein - - - 0.0000009868 53.0
HKD2_k127_438981_0 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 6.473e-254 801.0
HKD2_k127_438981_1 Glycosyltransferase Family 4 - - - 1.763e-222 715.0
HKD2_k127_438981_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000003106 221.0
HKD2_k127_438981_11 EVE domain - - - 0.000000000000000000000000000000000000000000000002878 178.0
HKD2_k127_438981_13 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000003462 50.0
HKD2_k127_438981_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 524.0
HKD2_k127_438981_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 486.0
HKD2_k127_438981_4 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 372.0
HKD2_k127_438981_5 Ornithine cyclodeaminase/mu-crystallin family K01750,K18258,K19244 - 1.4.1.1,1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 325.0
HKD2_k127_438981_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008991 259.0
HKD2_k127_438981_7 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
HKD2_k127_438981_8 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003525 233.0
HKD2_k127_438981_9 Uncharacterized protein conserved in bacteria (DUF2334) K06986 - - 0.00000000000000000000000000000000000000000000000000000000000000025 231.0
HKD2_k127_4453048_0 CoA binding domain K09181 - - 0.0 1108.0
HKD2_k127_4453048_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 444.0
HKD2_k127_4453048_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002386 284.0
HKD2_k127_4453048_3 DoxX-like family - - - 0.00000000000000000000000000000003028 130.0
HKD2_k127_4453048_4 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02005 - - 0.0000000000000000004943 88.0
HKD2_k127_4461922_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 503.0
HKD2_k127_4461922_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 407.0
HKD2_k127_4461922_2 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000002431 214.0
HKD2_k127_4468267_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.366e-209 668.0
HKD2_k127_4468267_1 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 600.0
HKD2_k127_4468267_10 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000754 175.0
HKD2_k127_4468267_11 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000000000000000000000007016 161.0
HKD2_k127_4468267_12 TIGRFAM RNA polymerase sigma factor, sigma-70 family - - - 0.0000000000000000000000000000000000003238 147.0
HKD2_k127_4468267_13 Protein of unknown function (DUF1573) - - - 0.000000000000000000000000000005457 127.0
HKD2_k127_4468267_14 Rhodanese Homology Domain - - - 0.0000000000000000000000008212 109.0
HKD2_k127_4468267_15 - - - - 0.000000000000000000000003706 105.0
HKD2_k127_4468267_16 CsbD-like - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000008778 98.0
HKD2_k127_4468267_17 - - - - 0.000000000000000003803 90.0
HKD2_k127_4468267_18 Methylamine utilisation protein MauE - - - 0.0000000000000003139 85.0
HKD2_k127_4468267_19 Protein of unknown function (DUF3309) - - - 0.000000000001516 68.0
HKD2_k127_4468267_2 SigmaW regulon antibacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 435.0
HKD2_k127_4468267_20 - - - - 0.000000002596 66.0
HKD2_k127_4468267_23 Trypsin - - - 0.000001051 60.0
HKD2_k127_4468267_24 PHP domain protein K07053 - 3.1.3.97 0.00003477 54.0
HKD2_k127_4468267_3 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 449.0
HKD2_k127_4468267_4 Male sterility protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 422.0
HKD2_k127_4468267_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 432.0
HKD2_k127_4468267_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 310.0
HKD2_k127_4468267_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002282 280.0
HKD2_k127_4468267_8 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 269.0
HKD2_k127_4468267_9 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
HKD2_k127_4661323_0 ABC transporter transmembrane region K06147 - - 2.964e-276 874.0
HKD2_k127_4661323_1 Magnesium chelatase, subunit ChlI - - - 0.000000000000000000000000000000000000000000000000000000000000000001329 239.0
HKD2_k127_4661323_2 Alternative locus ID K02022 - - 0.00000000000000000001076 105.0
HKD2_k127_4709412_0 Fumarylacetoacetase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 461.0
HKD2_k127_4709412_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 340.0
HKD2_k127_4709412_2 histidyl-tRNA synthetase - - - 0.0000000000000000000000000000000000000000000000000000000002244 214.0
HKD2_k127_4709412_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K00587 - 2.1.1.100 0.0000000000000000000000000000000000000001429 157.0
HKD2_k127_4709412_4 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000002695 93.0
HKD2_k127_471461_0 PFAM ATP dependent DNA ligase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 434.0
HKD2_k127_471461_1 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 417.0
HKD2_k127_471461_2 PFAM Ribonuclease BN-like family K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000368 284.0
HKD2_k127_471461_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000001469 62.0
HKD2_k127_471461_4 Domain of unknown function (DUF2383) - - - 0.0000006857 53.0
HKD2_k127_4798816_0 type II secretion system protein E K02652 - - 3.776e-262 817.0
HKD2_k127_4798816_1 Type II/IV secretion system protein K02652 - - 2.21e-204 650.0
HKD2_k127_4798816_2 Proteasomal ATPase OB/ID domain K13527 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 570.0
HKD2_k127_4798816_3 type II secretion K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 534.0
HKD2_k127_4798816_4 Beta-lactamase superfamily domain - - - 0.00003175 51.0
HKD2_k127_4822329_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1499.0
HKD2_k127_4822329_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 488.0
HKD2_k127_4822329_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000002976 224.0
HKD2_k127_4822329_3 Fe-S metabolism associated domain K02426 - - 0.0000000000000000000000000000000000000000000000000000000000008936 213.0
HKD2_k127_4822329_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000003256 206.0
HKD2_k127_4822329_5 HemY domain protein - - - 0.0000000000000000000000000000003704 133.0
HKD2_k127_4822329_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.00000000000000003246 85.0
HKD2_k127_4822329_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000008799 69.0
HKD2_k127_4822329_8 Copper binding proteins, plastocyanin/azurin family - - - 0.00005102 52.0
HKD2_k127_5037231_0 TIGRFAM ATP-dependent DNA helicase, RecQ family K03654 - 3.6.4.12 1.68e-280 874.0
HKD2_k127_5037231_1 Amino acid permease K03294 - - 4.573e-200 634.0
HKD2_k127_5037231_10 - - - - 0.00000000000000000000000000000000000004985 153.0
HKD2_k127_5037231_11 - - - - 0.0000000000000000000000000000000002766 142.0
HKD2_k127_5037231_12 HlyD family secretion protein K01993 - - 0.000000000000000000000000000008939 130.0
HKD2_k127_5037231_13 Belongs to the UPF0312 family - - - 0.00000000000000000000000000006018 127.0
HKD2_k127_5037231_14 Peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000004994 119.0
HKD2_k127_5037231_15 - - - - 0.00000000000000001204 90.0
HKD2_k127_5037231_16 NMT1-like family K07080 - - 0.000000000000001101 87.0
HKD2_k127_5037231_17 PFAM Peptidase family M28 - - - 0.00000000000004339 75.0
HKD2_k127_5037231_18 Protein of unknwon function (DUF3008) - - - 0.0000000000001398 74.0
HKD2_k127_5037231_19 - - - - 0.00001498 54.0
HKD2_k127_5037231_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 524.0
HKD2_k127_5037231_3 Allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 431.0
HKD2_k127_5037231_4 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 380.0
HKD2_k127_5037231_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 324.0
HKD2_k127_5037231_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003314 286.0
HKD2_k127_5037231_7 Belongs to the UPF0271 (lamB) family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
HKD2_k127_5037231_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000005536 214.0
HKD2_k127_5037231_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000929 197.0
HKD2_k127_5039622_0 PFAM membrane bound O-acyl transferase MBOAT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 415.0
HKD2_k127_5039622_1 PFAM mannose-6-phosphate isomerase type I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 334.0
HKD2_k127_5039622_2 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003416 246.0
HKD2_k127_5039622_3 cellulase activity - - - 0.000000000000000000000000000000000000000000000005934 188.0
HKD2_k127_5039622_5 VanZ like family - - - 0.0000000000000000000182 97.0
HKD2_k127_5039720_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 581.0
HKD2_k127_5039720_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
HKD2_k127_5039720_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 317.0
HKD2_k127_5039720_4 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000871 216.0
HKD2_k127_5039720_5 Glycine D-amino acid oxidases (deaminating) K00273 - 1.4.3.3 0.00000000000000000000000000000000000000000000000000000000005513 217.0
HKD2_k127_5039720_6 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000002638 186.0
HKD2_k127_5039720_8 - - - - 0.000000000001463 72.0
HKD2_k127_5039720_9 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0005003 45.0
HKD2_k127_5040606_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.811e-222 698.0
HKD2_k127_5040606_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 598.0
HKD2_k127_5040606_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.000000000000000000000000000000000000002971 149.0
HKD2_k127_5040606_11 TPM domain - - - 0.0000000000000000000000000000000000004632 147.0
HKD2_k127_5040606_12 Domain of unknown function (DUF4440) - - - 0.00000000007473 69.0
HKD2_k127_5040606_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 486.0
HKD2_k127_5040606_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 316.0
HKD2_k127_5040606_4 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 306.0
HKD2_k127_5040606_5 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 306.0
HKD2_k127_5040606_6 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
HKD2_k127_5040606_7 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000003294 224.0
HKD2_k127_5040606_8 Segregation and condensation complex subunit ScpB - - - 0.000000000000000000000000000000000000000000000000000000005379 206.0
HKD2_k127_5040606_9 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000003611 159.0
HKD2_k127_5091565_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.941e-202 636.0
HKD2_k127_5091565_1 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 560.0
HKD2_k127_5091565_2 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000622 220.0
HKD2_k127_5091565_3 Major Facilitator Superfamily - - - 0.0000000003301 65.0
HKD2_k127_5105897_0 Protein of unknown function (DUF3604) - - - 1.122e-235 739.0
HKD2_k127_5105897_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 524.0
HKD2_k127_5105897_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000007478 212.0
HKD2_k127_5105897_3 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000007299 160.0
HKD2_k127_5105897_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000001521 96.0
HKD2_k127_5105897_5 cheY-homologous receiver domain - - - 0.000000000000000001788 89.0
HKD2_k127_5105897_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000005316 64.0
HKD2_k127_5122510_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 475.0
HKD2_k127_5122510_1 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000001081 138.0
HKD2_k127_5132257_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 585.0
HKD2_k127_5132257_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 452.0
HKD2_k127_5132257_10 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000008225 102.0
HKD2_k127_5132257_11 nuclear chromosome segregation - - - 0.000000000000000002599 96.0
HKD2_k127_5132257_12 SPW repeat - - - 0.00000000000000003305 87.0
HKD2_k127_5132257_14 oxidation-reduction process - - - 0.00003064 52.0
HKD2_k127_5132257_2 Aminotransferase class-V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 433.0
HKD2_k127_5132257_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 335.0
HKD2_k127_5132257_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 332.0
HKD2_k127_5132257_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008478 248.0
HKD2_k127_5132257_6 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000001139 189.0
HKD2_k127_5132257_7 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000004956 181.0
HKD2_k127_5132257_8 YacP-like NYN domain K06962 - - 0.000000000000000000000000000000000000000000341 162.0
HKD2_k127_5132844_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
HKD2_k127_5132844_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000001074 114.0
HKD2_k127_5163552_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 348.0
HKD2_k127_5163552_1 Glycosyl transferases group 1 K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000000000000000006748 231.0
HKD2_k127_5163552_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000001459 74.0
HKD2_k127_5164093_0 TIGRFAM LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 440.0
HKD2_k127_5164093_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 414.0
HKD2_k127_5164093_10 - - - - 0.000001919 51.0
HKD2_k127_5164093_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 338.0
HKD2_k127_5164093_3 Predicted integral membrane protein (DUF2270) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
HKD2_k127_5164093_4 short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 298.0
HKD2_k127_5164093_5 - - - - 0.0000000000000000002261 93.0
HKD2_k127_5164093_6 GYD domain - - - 0.0000000000000000002698 89.0
HKD2_k127_5164093_7 photosystem II stabilization - - - 0.0000000000001643 76.0
HKD2_k127_5164093_8 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 GO:0001932,GO:0001934,GO:0003674,GO:0003824,GO:0004857,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0008047,GO:0008150,GO:0008643,GO:0009401,GO:0009893,GO:0010033,GO:0010243,GO:0010562,GO:0010604,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0019207,GO:0019209,GO:0019220,GO:0019222,GO:0019887,GO:0022804,GO:0022857,GO:0022898,GO:0030234,GO:0030295,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032147,GO:0032268,GO:0032270,GO:0032409,GO:0032412,GO:0032879,GO:0033674,GO:0034219,GO:0034762,GO:0034765,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043086,GO:0043269,GO:0043549,GO:0044092,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051049,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0055085,GO:0060255,GO:0065007,GO:0065009,GO:0071702,GO:0071944,GO:0080090,GO:0090563,GO:0098772,GO:1901698 2.7.1.202 0.000000000002571 73.0
HKD2_k127_5179728_0 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 597.0
HKD2_k127_5179728_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 374.0
HKD2_k127_5179728_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 362.0
HKD2_k127_5179728_3 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 352.0
HKD2_k127_5179728_4 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000188 241.0
HKD2_k127_5179728_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000007679 223.0
HKD2_k127_5182431_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 452.0
HKD2_k127_5182431_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 451.0
HKD2_k127_5182431_2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375,K05825 - - 0.000000000000000000004336 97.0
HKD2_k127_5182431_3 ATP-binding region ATPase domain protein - - - 0.000302 48.0
HKD2_k127_5198507_0 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 572.0
HKD2_k127_5198507_1 DNA ligase N terminus K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 564.0
HKD2_k127_5198507_10 - - - - 0.0000000000000000000000000000000003975 135.0
HKD2_k127_5198507_11 - - - - 0.00000000000000000000000000000003709 134.0
HKD2_k127_5198507_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 519.0
HKD2_k127_5198507_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 464.0
HKD2_k127_5198507_4 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 341.0
HKD2_k127_5198507_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 306.0
HKD2_k127_5198507_6 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 300.0
HKD2_k127_5198507_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215,K15331 - 2.1.1.190,2.1.1.35 0.000000000000000000000000000000000000000000000000000000001831 210.0
HKD2_k127_5198507_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000007131 175.0
HKD2_k127_5198507_9 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000007238 175.0
HKD2_k127_5214725_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2260.0
HKD2_k127_5214725_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2186.0
HKD2_k127_5214725_10 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000023 286.0
HKD2_k127_5214725_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005065 260.0
HKD2_k127_5214725_12 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000001337 243.0
HKD2_k127_5214725_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000001476 231.0
HKD2_k127_5214725_14 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.00000000000000000000000000000000000000000000000000000000000000001567 249.0
HKD2_k127_5214725_15 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000004424 231.0
HKD2_k127_5214725_16 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000001414 216.0
HKD2_k127_5214725_17 Cobalamin adenosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001943 200.0
HKD2_k127_5214725_18 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000024 168.0
HKD2_k127_5214725_19 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000007473 162.0
HKD2_k127_5214725_2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 1.067e-282 885.0
HKD2_k127_5214725_20 - - - - 0.00000000000000000000004845 109.0
HKD2_k127_5214725_21 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000005397 101.0
HKD2_k127_5214725_3 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 582.0
HKD2_k127_5214725_4 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 538.0
HKD2_k127_5214725_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 484.0
HKD2_k127_5214725_6 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 428.0
HKD2_k127_5214725_7 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 358.0
HKD2_k127_5214725_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 353.0
HKD2_k127_5214725_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 299.0
HKD2_k127_5216284_0 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 394.0
HKD2_k127_5216284_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 310.0
HKD2_k127_5216284_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215,K15331 - 2.1.1.190,2.1.1.35 0.0000000000000000000000000000009926 126.0
HKD2_k127_5248704_0 transferase K01027 - 2.8.3.5 6.977e-234 730.0
HKD2_k127_5248704_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 385.0
HKD2_k127_5248704_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000000000000007264 223.0
HKD2_k127_5248704_4 SERine Proteinase INhibitors - - - 0.0000000000000000000003886 96.0
HKD2_k127_5248704_5 AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.0000000000000006793 83.0
HKD2_k127_5248704_6 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000002971 76.0
HKD2_k127_5255854_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 500.0
HKD2_k127_5255854_1 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 385.0
HKD2_k127_5255854_10 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000000000000000001456 181.0
HKD2_k127_5255854_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000002417 168.0
HKD2_k127_5255854_12 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000004904 145.0
HKD2_k127_5255854_13 - K01992,K19341 - - 0.0000000000000000000000000000002677 133.0
HKD2_k127_5255854_14 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000001209 102.0
HKD2_k127_5255854_15 Cupredoxin-like domain K00376 - 1.7.2.4 0.00000000000000000001973 91.0
HKD2_k127_5255854_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000004003 79.0
HKD2_k127_5255854_17 PFAM Universal stress protein family - - - 0.0008264 43.0
HKD2_k127_5255854_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 378.0
HKD2_k127_5255854_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 342.0
HKD2_k127_5255854_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005506 308.0
HKD2_k127_5255854_5 Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001978 274.0
HKD2_k127_5255854_6 NnrS protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000181 251.0
HKD2_k127_5255854_7 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000306 237.0
HKD2_k127_5255854_8 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000007554 213.0
HKD2_k127_5255854_9 DNA-templated transcription, initiation - - - 0.0000000000000000000000000000000000000000000000000001631 196.0
HKD2_k127_5259003_0 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 521.0
HKD2_k127_5259003_1 Nicotine adenine dinucleotide glycohydrolase (NADase) - - - 0.00000000000000000000000000000000000008684 152.0
HKD2_k127_5362971_0 KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 539.0
HKD2_k127_5362971_1 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 423.0
HKD2_k127_5362971_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000001941 225.0
HKD2_k127_5362971_3 inorganic diphosphatase activity K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000002668 195.0
HKD2_k127_5362971_4 Domain of unknown function (DUF2383) - - - 0.0000000000000000000000000000000000000001718 154.0
HKD2_k127_5362971_5 - - - - 0.0000000000000000000000000000000000000004763 154.0
HKD2_k127_5362971_6 Histidine kinase - - - 0.000000000000000000000000000000000000006862 161.0
HKD2_k127_5362971_8 Histidine kinase - - - 0.00004794 55.0
HKD2_k127_5364043_0 Belongs to the glycosyl hydrolase 26 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 431.0
HKD2_k127_5364043_1 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 385.0
HKD2_k127_5364043_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000002816 139.0
HKD2_k127_5364043_3 - - - - 0.00000000003097 72.0
HKD2_k127_5373143_0 Glycosyl transferase family 21 - - - 0.0 1046.0
HKD2_k127_5373143_1 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 5.644e-194 613.0
HKD2_k127_5373143_2 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 406.0
HKD2_k127_5373143_3 - - - - 0.0000000000000000000000000000000000000000002989 164.0
HKD2_k127_5412501_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000002056 155.0
HKD2_k127_5412501_1 beta-lactamase activity K07126 GO:0006950,GO:0006979,GO:0008150,GO:0050896 - 0.00000000000000000000000000000045 138.0
HKD2_k127_5412501_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00008475 53.0
HKD2_k127_542556_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 496.0
HKD2_k127_542556_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 333.0
HKD2_k127_542556_2 Translation initiation inhibitor, yjgF family K15067 - 3.5.99.5 0.000000000000000000000000000000000000000000000000000000008729 200.0
HKD2_k127_542556_3 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000005402 169.0
HKD2_k127_542556_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000001433 163.0
HKD2_k127_542556_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000003151 154.0
HKD2_k127_542556_6 COG0846 NAD-dependent protein deacetylases, SIR2 family - - - 0.00000000000000001034 86.0
HKD2_k127_542556_7 Domain of unknown function (DUF4440) - - - 0.00000007742 54.0
HKD2_k127_542556_8 Domain of unknown function (DUF4440) - - - 0.000006976 50.0
HKD2_k127_5431757_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1104.0
HKD2_k127_5431757_1 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000001352 216.0
HKD2_k127_5431757_2 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000005772 154.0
HKD2_k127_5431757_3 - - - - 0.000000000000000000000000000000000001687 142.0
HKD2_k127_5431757_4 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000782 74.0
HKD2_k127_5431757_5 - - - - 0.0007057 48.0
HKD2_k127_5449678_0 Pup-ligase protein K13571 - 6.3.1.19 1.177e-210 663.0
HKD2_k127_5449678_1 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000002747 171.0
HKD2_k127_5449678_2 PFAM Mg2 transporter protein CorA family protein K16074 - - 0.0000000000000000000000000000009402 126.0
HKD2_k127_5449678_3 UPF0391 membrane protein - - - 0.000000001509 59.0
HKD2_k127_545489_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 1.928e-259 812.0
HKD2_k127_545489_1 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000007182 171.0
HKD2_k127_5455889_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 563.0
HKD2_k127_5455889_1 DNA polymerase IV (family X) K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 542.0
HKD2_k127_5455889_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 462.0
HKD2_k127_5455889_3 Peptidase family M54 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006977 265.0
HKD2_k127_5455889_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000001112 152.0
HKD2_k127_5455889_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000007082 126.0
HKD2_k127_5460420_0 Alpha beta hydrolase - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 599.0
HKD2_k127_5460420_1 Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 362.0
HKD2_k127_5460420_2 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000003311 209.0
HKD2_k127_5460420_3 Acyl-transferase K00655,K01897 - 2.3.1.51,6.2.1.3 0.00000000000000000000000000000000000000004707 164.0
HKD2_k127_5460420_4 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.00000000000000000000000006522 115.0
HKD2_k127_5460420_5 Dual specificity phosphatase, catalytic domain - - - 0.000000001412 61.0
HKD2_k127_5477026_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.546e-198 625.0
HKD2_k127_5477026_1 Seryl-tRNA synthetase N-terminal domain K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 516.0
HKD2_k127_5477026_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000004403 159.0
HKD2_k127_5477026_11 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000006939 149.0
HKD2_k127_5477026_12 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000007645 129.0
HKD2_k127_5477026_13 - - - - 0.0000000000000000002221 94.0
HKD2_k127_5477026_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 494.0
HKD2_k127_5477026_3 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 479.0
HKD2_k127_5477026_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 467.0
HKD2_k127_5477026_5 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 454.0
HKD2_k127_5477026_6 SRP54-type protein, GTPase domain K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 316.0
HKD2_k127_5477026_7 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 318.0
HKD2_k127_5477026_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000001895 223.0
HKD2_k127_5477026_9 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000001447 213.0
HKD2_k127_548017_0 Multicopper oxidase K00368 - 1.7.2.1 4.305e-230 722.0
HKD2_k127_548017_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 435.0
HKD2_k127_548017_10 Parallel beta-helix repeats K12287 - - 0.0000000000000000000000000000000000000000000000000009706 198.0
HKD2_k127_548017_11 - - - - 0.00000000000000000000000000000000000000000000000001666 187.0
HKD2_k127_548017_12 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000166 161.0
HKD2_k127_548017_13 transcriptional regulator K13771 - - 0.0000000000000000000000000000000003107 136.0
HKD2_k127_548017_15 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000001305 71.0
HKD2_k127_548017_16 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000001419 70.0
HKD2_k127_548017_17 - - - - 0.0000001145 66.0
HKD2_k127_548017_19 - - - - 0.000408 43.0
HKD2_k127_548017_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 411.0
HKD2_k127_548017_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 328.0
HKD2_k127_548017_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 319.0
HKD2_k127_548017_5 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 291.0
HKD2_k127_548017_6 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003044 273.0
HKD2_k127_548017_7 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000005093 229.0
HKD2_k127_548017_8 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000006171 211.0
HKD2_k127_548017_9 DNA-templated transcription, initiation K02405 - - 0.00000000000000000000000000000000000000000000000000000002701 202.0
HKD2_k127_5498977_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001349 285.0
HKD2_k127_5498977_1 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000002196 209.0
HKD2_k127_5498977_2 Resolvase, N terminal domain K06400 - - 0.000000000000000000000000000000000000000001694 163.0
HKD2_k127_5498977_3 Autotransporter beta-domain - - - 0.0000000000000006408 87.0
HKD2_k127_5515259_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 2.344e-236 747.0
HKD2_k127_5515259_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 548.0
HKD2_k127_5515259_10 DNA ligase N terminus K07577,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000002546 104.0
HKD2_k127_5515259_11 - - - - 0.00000000000001501 79.0
HKD2_k127_5515259_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 473.0
HKD2_k127_5515259_3 response regulator, receiver K07315,K20977 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 312.0
HKD2_k127_5515259_4 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000001488 249.0
HKD2_k127_5515259_5 belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K02945,K03527,K03977,K11753,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.17.7.4,2.5.1.19,2.7.1.26,2.7.4.25,2.7.7.2,6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000002067 230.0
HKD2_k127_5515259_6 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000007686 159.0
HKD2_k127_5515259_7 mRNA catabolic process K06950,K09163 - - 0.0000000000000000000000000000000000005218 146.0
HKD2_k127_5515259_8 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000002202 124.0
HKD2_k127_5515259_9 Putative regulatory protein - - - 0.000000000000000000000000000001305 125.0
HKD2_k127_552303_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1252.0
HKD2_k127_552303_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001447 259.0
HKD2_k127_552303_2 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000004605 242.0
HKD2_k127_552303_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000004321 207.0
HKD2_k127_552303_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000002581 175.0
HKD2_k127_552303_5 3D domain protein K21471 - - 0.0000000000000000000000000000000004291 138.0
HKD2_k127_552303_6 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000007532 120.0
HKD2_k127_552303_7 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000008182 120.0
HKD2_k127_552303_8 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000003667 57.0
HKD2_k127_5542628_0 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 594.0
HKD2_k127_5542628_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 349.0
HKD2_k127_5542628_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 269.0
HKD2_k127_5542628_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000007051 99.0
HKD2_k127_5563946_0 Patatin phospholipase - - - 1.31e-256 812.0
HKD2_k127_5563946_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000003307 55.0
HKD2_k127_559096_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1178.0
HKD2_k127_559096_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 9.455e-227 712.0
HKD2_k127_559096_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 330.0
HKD2_k127_559096_11 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 299.0
HKD2_k127_559096_12 ABC-type transport system involved in multi-copper enzyme maturation permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 299.0
HKD2_k127_559096_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009557 278.0
HKD2_k127_559096_14 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004561 265.0
HKD2_k127_559096_15 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004879 253.0
HKD2_k127_559096_16 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002448 250.0
HKD2_k127_559096_17 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009281 248.0
HKD2_k127_559096_18 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000002596 237.0
HKD2_k127_559096_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 233.0
HKD2_k127_559096_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 544.0
HKD2_k127_559096_20 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000009552 232.0
HKD2_k127_559096_21 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
HKD2_k127_559096_22 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000002131 226.0
HKD2_k127_559096_23 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
HKD2_k127_559096_24 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000007208 213.0
HKD2_k127_559096_25 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000001782 202.0
HKD2_k127_559096_26 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000002424 196.0
HKD2_k127_559096_27 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000003085 194.0
HKD2_k127_559096_28 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000003213 188.0
HKD2_k127_559096_29 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000001159 186.0
HKD2_k127_559096_3 DHHA1 domain K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 524.0
HKD2_k127_559096_30 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000007362 176.0
HKD2_k127_559096_31 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000004426 163.0
HKD2_k127_559096_32 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000007627 158.0
HKD2_k127_559096_33 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000006826 136.0
HKD2_k127_559096_34 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000458 127.0
HKD2_k127_559096_35 - - - - 0.00000000000000000000000000001121 128.0
HKD2_k127_559096_36 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000001434 114.0
HKD2_k127_559096_37 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000001901 113.0
HKD2_k127_559096_38 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000001896 93.0
HKD2_k127_559096_39 Ribosomal L29 protein K02904 - - 0.000000000000004721 77.0
HKD2_k127_559096_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 490.0
HKD2_k127_559096_40 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000004374 66.0
HKD2_k127_559096_5 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 421.0
HKD2_k127_559096_6 RecG wedge domain K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 419.0
HKD2_k127_559096_7 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 391.0
HKD2_k127_559096_8 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 357.0
HKD2_k127_559096_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 333.0
HKD2_k127_5639116_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 445.0
HKD2_k127_5639116_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000005375 150.0
HKD2_k127_5678042_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 2.078e-261 841.0
HKD2_k127_5678042_1 Pyruvate:ferredoxin oxidoreductase core domain II - - - 2.083e-250 788.0
HKD2_k127_5678042_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 527.0
HKD2_k127_5678042_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 442.0
HKD2_k127_5678042_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 426.0
HKD2_k127_5678042_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 331.0
HKD2_k127_5678042_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007469 278.0
HKD2_k127_5678042_7 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000002062 132.0
HKD2_k127_572744_0 His Kinase A (phosphoacceptor) domain - - - 9.284e-316 998.0
HKD2_k127_572744_1 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.0000000000000000000000000000000000001316 156.0
HKD2_k127_572744_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000002118 63.0
HKD2_k127_572744_3 - - - - 0.0000002437 56.0
HKD2_k127_5762568_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 596.0
HKD2_k127_5762568_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 488.0
HKD2_k127_5762568_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 473.0
HKD2_k127_5762568_3 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000006621 209.0
HKD2_k127_5762568_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000001542 164.0
HKD2_k127_5762568_5 Sulfotransferase domain - - - 0.000000000000000000000000271 111.0
HKD2_k127_5762568_6 - - - - 0.0000000000000000000003252 98.0
HKD2_k127_5844869_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.498e-250 781.0
HKD2_k127_5844869_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001577 287.0
HKD2_k127_5844869_2 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000005563 131.0
HKD2_k127_5880662_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 392.0
HKD2_k127_5880662_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 338.0
HKD2_k127_5880662_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001113 244.0
HKD2_k127_5880662_3 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000008835 178.0
HKD2_k127_5880662_4 Methyltransferase domain - - - 0.000000000000000000000004479 104.0
HKD2_k127_5880662_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000127 94.0
HKD2_k127_5910486_0 Aminotransferase class I and II K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 353.0
HKD2_k127_5910486_1 TonB-linked outer membrane protein, SusC RagA family - - - 0.0003955 50.0
HKD2_k127_5933214_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003541 256.0
HKD2_k127_5933214_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000004475 55.0
HKD2_k127_5933214_2 Asparagine synthase K01953 - 6.3.5.4 0.0004827 44.0
HKD2_k127_618217_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 538.0
HKD2_k127_618217_1 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
HKD2_k127_618217_2 - - - - 0.0000000000000000000006816 100.0
HKD2_k127_618217_3 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000007297 64.0
HKD2_k127_618217_4 hydrolase K01048 - 3.1.1.5 0.000009944 49.0
HKD2_k127_6186463_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 581.0
HKD2_k127_6186463_1 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001131 256.0
HKD2_k127_6186463_2 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000001699 246.0
HKD2_k127_6186463_3 Arylsulfatase family, member K K12376 GO:0003674,GO:0003824,GO:0004065,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0008484,GO:0012505,GO:0016787,GO:0016788,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070013 - 0.000000000000000000000000000001915 126.0
HKD2_k127_6186463_4 Peptidase family M48 - - - 0.0000000000000000001965 104.0
HKD2_k127_6186463_5 - - - - 0.000001308 57.0
HKD2_k127_6228438_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 401.0
HKD2_k127_6228438_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001325 179.0
HKD2_k127_6228438_2 Acyl-ACP thioesterase K07107 - - 0.000000000000000000000000000000000000000000005651 166.0
HKD2_k127_6228438_3 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000004068 121.0
HKD2_k127_6228438_4 Large extracellular alpha-helical protein - - - 0.00000000000000000003194 96.0
HKD2_k127_6228438_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000585 72.0
HKD2_k127_6228438_6 - - - - 0.000000007817 64.0
HKD2_k127_6228438_7 Cytochrome oxidase complex assembly protein 1 - - - 0.0000005352 53.0
HKD2_k127_6228438_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00002196 55.0
HKD2_k127_624493_0 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0 1162.0
HKD2_k127_624493_1 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 551.0
HKD2_k127_624493_10 Protein of unknown function (DUF2933) - - - 0.000000000000000000000004082 104.0
HKD2_k127_624493_11 Domain of unknown function (DUF1330) - - - 0.00000000000000001312 88.0
HKD2_k127_624493_12 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0000000000000001209 84.0
HKD2_k127_624493_2 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 496.0
HKD2_k127_624493_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K09251 - 2.6.1.11,2.6.1.17,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 425.0
HKD2_k127_624493_4 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 376.0
HKD2_k127_624493_5 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003005 259.0
HKD2_k127_624493_6 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001627 248.0
HKD2_k127_624493_7 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002755 232.0
HKD2_k127_624493_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000003212 171.0
HKD2_k127_624493_9 - - - - 0.000000000000000000000000000175 125.0
HKD2_k127_6255400_0 Cation transporter/ATPase, N-terminus K01531,K01537 - 3.6.3.2,3.6.3.8 0.0 1113.0
HKD2_k127_6255400_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 7.473e-248 779.0
HKD2_k127_6255400_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 394.0
HKD2_k127_6255400_3 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001344 263.0
HKD2_k127_6282756_0 Rieske (2fe-2S) K15060 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 335.0
HKD2_k127_6282756_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000005555 168.0
HKD2_k127_6282756_2 COG0471 Di- and tricarboxylate transporters - - - 0.000000000000000000000000001063 126.0
HKD2_k127_6385961_0 Beta-ketoacyl synthase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 576.0
HKD2_k127_6385961_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 484.0
HKD2_k127_6385961_2 tRNA (Guanine-1)-methyltransferase K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 312.0
HKD2_k127_6385961_3 negative regulation of translational initiation K05554,K15885 - - 0.0000000000000000000000000000000000000001241 154.0
HKD2_k127_6385961_4 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000891 94.0
HKD2_k127_6418134_0 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 565.0
HKD2_k127_6418134_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 454.0
HKD2_k127_6418134_2 Protein of unknown function (DUF3302) - - - 0.0000000000000000000000000000000000000000000000000000001974 198.0
HKD2_k127_6418134_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000006678 198.0
HKD2_k127_6436442_0 Peptidase family M13 K07386 - - 3.171e-237 752.0
HKD2_k127_6436442_1 COG0457 FOG TPR repeat - - - 1.567e-233 736.0
HKD2_k127_6436442_10 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 0.000000000000000000000000000000000000000003821 166.0
HKD2_k127_6436442_11 protein conserved in bacteria K09973 - - 0.000000000000000000000000000006848 133.0
HKD2_k127_6436442_12 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000002894 76.0
HKD2_k127_6436442_13 FAD dependent oxidoreductase K00301 - 1.5.3.1 0.00000000001001 66.0
HKD2_k127_6436442_14 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000001307 77.0
HKD2_k127_6436442_2 TamB, inner membrane protein subunit of TAM complex - - - 8.299e-194 652.0
HKD2_k127_6436442_3 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 510.0
HKD2_k127_6436442_4 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 468.0
HKD2_k127_6436442_5 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 451.0
HKD2_k127_6436442_6 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 438.0
HKD2_k127_6436442_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 357.0
HKD2_k127_6436442_8 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 357.0
HKD2_k127_6436442_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001959 166.0
HKD2_k127_6458335_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1015.0
HKD2_k127_6458335_1 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 4.966e-262 819.0
HKD2_k127_6458335_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000001527 158.0
HKD2_k127_6458335_12 membrane - - - 0.0000000000000000000000000000001122 137.0
HKD2_k127_6458335_13 - - - - 0.0000000000000000000000000001952 130.0
HKD2_k127_6458335_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000007325 110.0
HKD2_k127_6458335_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000004654 115.0
HKD2_k127_6458335_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 504.0
HKD2_k127_6458335_3 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 507.0
HKD2_k127_6458335_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 497.0
HKD2_k127_6458335_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 479.0
HKD2_k127_6458335_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003799 255.0
HKD2_k127_6458335_7 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000002771 212.0
HKD2_k127_6458335_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001723 178.0
HKD2_k127_6458335_9 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000006473 180.0
HKD2_k127_6480220_0 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 240.0
HKD2_k127_6480220_1 - - - - 0.00000000000000000000000000000000002082 144.0
HKD2_k127_6504509_0 arylsulfatase activity K01130 - 3.1.6.1 4.127e-316 972.0
HKD2_k127_6504509_1 Arylsulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 568.0
HKD2_k127_6504509_12 long-chain fatty acid transporting porin activity K06076 - - 0.000000000001611 74.0
HKD2_k127_6504509_13 - - - - 0.0000000001797 69.0
HKD2_k127_6504509_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 282.0
HKD2_k127_6504509_3 Major intrinsic protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001899 259.0
HKD2_k127_6504509_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003641 241.0
HKD2_k127_6504509_6 Ion channel - - - 0.000000000000000000000000000000000000000000000003326 181.0
HKD2_k127_6504509_7 Conserved Protein - - - 0.000000000000000000000000000000000000000000001148 172.0
HKD2_k127_6504509_8 Transglycosylase associated protein - - - 0.0000000000000000000000000000009749 123.0
HKD2_k127_6504509_9 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000001873 108.0
HKD2_k127_6506180_0 TRCF - - - 4.716e-303 963.0
HKD2_k127_6506180_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.675e-284 884.0
HKD2_k127_6506180_10 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 386.0
HKD2_k127_6506180_11 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000009856 265.0
HKD2_k127_6506180_12 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000004951 248.0
HKD2_k127_6506180_13 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001683 229.0
HKD2_k127_6506180_14 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000001771 216.0
HKD2_k127_6506180_15 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000004359 185.0
HKD2_k127_6506180_16 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000004446 122.0
HKD2_k127_6506180_17 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000003216 117.0
HKD2_k127_6506180_18 glutamine-fructose-6-phosphate transaminase (isomerizing) activity - - - 0.0000000000000000000009247 96.0
HKD2_k127_6506180_19 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000001319 87.0
HKD2_k127_6506180_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.905e-282 884.0
HKD2_k127_6506180_20 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.000000000000001003 80.0
HKD2_k127_6506180_21 ORF6N domain - - - 0.00000000000005628 76.0
HKD2_k127_6506180_3 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 611.0
HKD2_k127_6506180_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 538.0
HKD2_k127_6506180_5 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 504.0
HKD2_k127_6506180_6 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 504.0
HKD2_k127_6506180_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 469.0
HKD2_k127_6506180_8 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 446.0
HKD2_k127_6506180_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 425.0
HKD2_k127_6604879_0 Glycosyl hydrolase family 65, C-terminal domain - - - 0.0 1516.0
HKD2_k127_6604879_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 513.0
HKD2_k127_6604879_2 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 456.0
HKD2_k127_6604879_3 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000003404 167.0
HKD2_k127_6604879_4 light absorption - - - 0.000842 46.0
HKD2_k127_6605581_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006094 532.0
HKD2_k127_6605581_1 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000004992 168.0
HKD2_k127_6605581_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000002785 147.0
HKD2_k127_6624906_0 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 546.0
HKD2_k127_6624906_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 342.0
HKD2_k127_6624906_10 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000003326 151.0
HKD2_k127_6624906_11 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000006667 124.0
HKD2_k127_6624906_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 301.0
HKD2_k127_6624906_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 266.0
HKD2_k127_6624906_4 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000000001012 179.0
HKD2_k127_6624906_5 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000003609 188.0
HKD2_k127_6624906_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000001232 165.0
HKD2_k127_6624906_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000003278 164.0
HKD2_k127_6624906_8 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000003736 154.0
HKD2_k127_6624906_9 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000001602 149.0
HKD2_k127_6626614_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1244.0
HKD2_k127_6626614_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1106.0
HKD2_k127_6626614_10 self proteolysis - - - 0.0000000000000000000000000000000000000000000000000000000000125 213.0
HKD2_k127_6626614_11 EamA-like transporter family K07790 - - 0.000000000000000000000000000000000003791 150.0
HKD2_k127_6626614_12 RF-1 domain - - - 0.000000000000000000000000000001147 127.0
HKD2_k127_6626614_13 Stf0 sulphotransferase K21014 - 2.8.2.37 0.000000000000000000000001797 113.0
HKD2_k127_6626614_14 Subtilase family K14645 - - 0.000000000000000003037 98.0
HKD2_k127_6626614_15 Papain-like cysteine protease AvrRpt2 - - - 0.0000000000000001733 88.0
HKD2_k127_6626614_16 - - - - 0.000000000001886 72.0
HKD2_k127_6626614_17 - - - - 0.000000000004315 72.0
HKD2_k127_6626614_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 610.0
HKD2_k127_6626614_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 485.0
HKD2_k127_6626614_5 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001195 258.0
HKD2_k127_6626614_6 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004661 240.0
HKD2_k127_6626614_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000005157 235.0
HKD2_k127_6626614_8 DNA integration K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000001462 245.0
HKD2_k127_6626614_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000001209 226.0
HKD2_k127_6649364_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1210.0
HKD2_k127_6649364_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 5.347e-319 993.0
HKD2_k127_6649364_2 Serine dehydratase beta chain - - - 1.324e-281 872.0
HKD2_k127_6649364_3 secondary active sulfate transmembrane transporter activity K03321 - - 2.116e-235 739.0
HKD2_k127_6649364_4 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 496.0
HKD2_k127_6649364_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 483.0
HKD2_k127_6649364_6 protein secretion K15125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 387.0
HKD2_k127_6649364_7 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 324.0
HKD2_k127_6649364_8 Ion channel - - - 0.00000000000000000000000000000000000002918 147.0
HKD2_k127_6649364_9 - - - - 0.0000000000000000000000000015 122.0
HKD2_k127_6693619_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1270.0
HKD2_k127_6693619_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 468.0
HKD2_k127_6693619_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000003494 182.0
HKD2_k127_6693619_11 S1/P1 Nuclease - - - 0.00000000000000000000000000003972 130.0
HKD2_k127_6693619_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 464.0
HKD2_k127_6693619_3 C-terminal domain of 1-Cys peroxiredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 391.0
HKD2_k127_6693619_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 361.0
HKD2_k127_6693619_5 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 324.0
HKD2_k127_6693619_6 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004659 284.0
HKD2_k127_6693619_7 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005177 271.0
HKD2_k127_6693619_8 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000471 261.0
HKD2_k127_6693619_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000004532 236.0
HKD2_k127_6703687_0 carbohydrate binding K13688 - - 0.0 2788.0
HKD2_k127_6703687_1 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000000000000000008924 233.0
HKD2_k127_6703687_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001782 189.0
HKD2_k127_6703687_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000006386 125.0
HKD2_k127_6703687_4 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000008013 126.0
HKD2_k127_6703687_5 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000001012 106.0
HKD2_k127_6703687_6 Adenylate cyclase - - - 0.00000000003206 72.0
HKD2_k127_6705643_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1050.0
HKD2_k127_6705643_1 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1019.0
HKD2_k127_6705643_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 434.0
HKD2_k127_6705643_11 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 413.0
HKD2_k127_6705643_12 PFAM ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 415.0
HKD2_k127_6705643_13 Belongs to the amidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 374.0
HKD2_k127_6705643_14 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 335.0
HKD2_k127_6705643_15 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 328.0
HKD2_k127_6705643_16 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 309.0
HKD2_k127_6705643_17 Glycosyl hydrolases family 25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 296.0
HKD2_k127_6705643_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 297.0
HKD2_k127_6705643_19 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 283.0
HKD2_k127_6705643_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.546e-204 653.0
HKD2_k127_6705643_20 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002598 274.0
HKD2_k127_6705643_21 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001511 255.0
HKD2_k127_6705643_22 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001105 256.0
HKD2_k127_6705643_23 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001184 258.0
HKD2_k127_6705643_25 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000000000000000000000000000008923 237.0
HKD2_k127_6705643_26 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000001429 239.0
HKD2_k127_6705643_27 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000258 221.0
HKD2_k127_6705643_29 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000238 218.0
HKD2_k127_6705643_3 Transglycosylase - - - 2.026e-195 639.0
HKD2_k127_6705643_30 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000001419 202.0
HKD2_k127_6705643_31 - - - - 0.0000000000000000000000000000000000000000000000000009799 199.0
HKD2_k127_6705643_32 integral membrane protein - - - 0.000000000000000000000000000000000000000000000005673 184.0
HKD2_k127_6705643_33 Belongs to the amidase family - - - 0.000000000000000000000000000000000000000000001305 174.0
HKD2_k127_6705643_34 RNA recognition motif - - - 0.0000000000000000000000000000000000000000002787 166.0
HKD2_k127_6705643_35 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000007415 159.0
HKD2_k127_6705643_36 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000001016 154.0
HKD2_k127_6705643_37 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000003706 130.0
HKD2_k127_6705643_38 IS1 transposase - - - 0.00000000000000000000000000003823 120.0
HKD2_k127_6705643_39 PFAM IS1 transposase - - - 0.00000000000000000000000001888 114.0
HKD2_k127_6705643_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 509.0
HKD2_k127_6705643_40 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000003444 116.0
HKD2_k127_6705643_41 DNA-templated transcription, initiation - - - 0.0000000000000000000000001232 113.0
HKD2_k127_6705643_43 - - - - 0.0000000000005049 80.0
HKD2_k127_6705643_44 Hydroxysteroid dehydrogenase like 2 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 0.000000000003184 72.0
HKD2_k127_6705643_45 Sulfotransferase domain - - - 0.000000009561 66.0
HKD2_k127_6705643_46 - - - - 0.0000005821 61.0
HKD2_k127_6705643_47 Transposase IS200 like K07491 - - 0.000002832 49.0
HKD2_k127_6705643_48 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0006472 48.0
HKD2_k127_6705643_5 Protein of unknown function (DUF2891) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 487.0
HKD2_k127_6705643_6 Major facilitator Superfamily K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 455.0
HKD2_k127_6705643_7 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 446.0
HKD2_k127_6705643_8 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 434.0
HKD2_k127_6705643_9 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 427.0
HKD2_k127_6713992_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.709e-239 749.0
HKD2_k127_6713992_1 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 316.0
HKD2_k127_6713992_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001058 268.0
HKD2_k127_6713992_3 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003552 239.0
HKD2_k127_6713992_4 response regulator K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000001189 232.0
HKD2_k127_6713992_5 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000000000007078 205.0
HKD2_k127_6713992_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000002022 207.0
HKD2_k127_6728403_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 5.239e-217 686.0
HKD2_k127_6728403_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000001758 177.0
HKD2_k127_6728403_2 Belongs to the UPF0306 family K09979 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000001244 164.0
HKD2_k127_6728403_3 Carbon-nitrogen hydrolase K01501,K01502 - 3.5.5.1,3.5.5.7 0.000006245 49.0
HKD2_k127_6728403_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00004862 52.0
HKD2_k127_6759321_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1451.0
HKD2_k127_6759321_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.312e-260 809.0
HKD2_k127_6759321_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000001929 243.0
HKD2_k127_6759321_4 lactoylglutathione lyase activity K11210 - - 0.0000000000000000000000001636 111.0
HKD2_k127_6773987_0 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 1.426e-224 713.0
HKD2_k127_6773987_1 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 8.521e-209 667.0
HKD2_k127_6773987_10 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 324.0
HKD2_k127_6773987_11 Glycosyl transferase family 2 K00721 GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006479 282.0
HKD2_k127_6773987_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001361 259.0
HKD2_k127_6773987_13 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000001467 242.0
HKD2_k127_6773987_14 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000006385 217.0
HKD2_k127_6773987_15 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000006131 195.0
HKD2_k127_6773987_16 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000002614 153.0
HKD2_k127_6773987_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000001327 126.0
HKD2_k127_6773987_19 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000000000000001686 110.0
HKD2_k127_6773987_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 546.0
HKD2_k127_6773987_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000004964 102.0
HKD2_k127_6773987_21 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.00000000000000000000006246 116.0
HKD2_k127_6773987_22 23S rRNA-intervening sequence protein - - - 0.00000000000000000005071 104.0
HKD2_k127_6773987_23 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000009833 93.0
HKD2_k127_6773987_24 Domain of unknown function (DUF4349) - - - 0.0000000000000004485 93.0
HKD2_k127_6773987_25 - - - - 0.0000000000002158 74.0
HKD2_k127_6773987_26 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000003696 79.0
HKD2_k127_6773987_27 RNA pseudouridylate synthase K06180 - 5.4.99.23 0.000000000001843 68.0
HKD2_k127_6773987_28 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.0000000008905 65.0
HKD2_k127_6773987_29 - - - - 0.00000008147 61.0
HKD2_k127_6773987_3 DegT/DnrJ/EryC1/StrS aminotransferase family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 530.0
HKD2_k127_6773987_4 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 526.0
HKD2_k127_6773987_5 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 517.0
HKD2_k127_6773987_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 410.0
HKD2_k127_6773987_7 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 376.0
HKD2_k127_6773987_8 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 340.0
HKD2_k127_6773987_9 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 325.0
HKD2_k127_6796862_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 393.0
HKD2_k127_6796862_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 317.0
HKD2_k127_6796862_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000004902 265.0
HKD2_k127_6796862_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000254 203.0
HKD2_k127_6796862_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000002457 129.0
HKD2_k127_6798030_0 PFAM secretion protein HlyD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 301.0
HKD2_k127_6798030_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000001956 224.0
HKD2_k127_6798030_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000006531 63.0
HKD2_k127_6810171_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 0.0 1131.0
HKD2_k127_6810171_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.477e-233 739.0
HKD2_k127_6810171_2 Aldehyde dehydrogenase family - - - 1.104e-212 672.0
HKD2_k127_6810171_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 602.0
HKD2_k127_6810171_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 563.0
HKD2_k127_6810171_5 PFAM Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 359.0
HKD2_k127_6810171_6 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.0000000005207 63.0
HKD2_k127_6938307_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.905e-232 728.0
HKD2_k127_6938307_1 Amidohydrolase family - - - 3.214e-230 725.0
HKD2_k127_6938307_11 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 302.0
HKD2_k127_6938307_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 293.0
HKD2_k127_6938307_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
HKD2_k127_6938307_14 - - - - 0.000000000000000000000000000000000000000000000000003281 187.0
HKD2_k127_6938307_15 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000009184 177.0
HKD2_k127_6938307_16 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.000000000000000000000000000000007405 132.0
HKD2_k127_6938307_17 - - - - 0.000000000000000000000000000005369 129.0
HKD2_k127_6938307_19 - - - - 0.0000000000000000000000000205 112.0
HKD2_k127_6938307_2 Beta-Casp domain K07576 - - 1.115e-196 622.0
HKD2_k127_6938307_20 Belongs to the ompA family K03286 - - 0.000000000000000000004278 98.0
HKD2_k127_6938307_21 ankyrin repeats - - - 0.000000001202 66.0
HKD2_k127_6938307_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 508.0
HKD2_k127_6938307_4 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 444.0
HKD2_k127_6938307_5 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 424.0
HKD2_k127_6938307_6 MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 429.0
HKD2_k127_6938307_7 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 404.0
HKD2_k127_6938307_8 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 391.0
HKD2_k127_6938307_9 Possible lysine decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 377.0
HKD2_k127_6953229_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 595.0
HKD2_k127_6953229_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 547.0
HKD2_k127_6953229_10 Glutaredoxin K03675 - - 0.00000000000000000000000000000000000000000000000001584 188.0
HKD2_k127_6953229_11 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000607 160.0
HKD2_k127_6953229_12 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000006057 147.0
HKD2_k127_6953229_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000001849 132.0
HKD2_k127_6953229_14 This gene assignment is based in part on extensive secondary structures observed for the flanking sequences using the nucleic acid folding program MFOLD - - - 0.0000000000000000000000000002184 124.0
HKD2_k127_6953229_15 Protein of unknown function (DUF429) - - - 0.0000002164 56.0
HKD2_k127_6953229_16 ParB-like nuclease domain - - - 0.0000002443 58.0
HKD2_k127_6953229_17 Short C-terminal domain K08982 - - 0.000005084 54.0
HKD2_k127_6953229_18 - - - - 0.0002294 44.0
HKD2_k127_6953229_19 Resolvase, N terminal domain - - - 0.0004094 51.0
HKD2_k127_6953229_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 542.0
HKD2_k127_6953229_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 505.0
HKD2_k127_6953229_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 316.0
HKD2_k127_6953229_5 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 312.0
HKD2_k127_6953229_6 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003914 279.0
HKD2_k127_6953229_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 267.0
HKD2_k127_6953229_9 Osmc family - - - 0.00000000000000000000000000000000000000000000000000000002372 199.0
HKD2_k127_7091439_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 621.0
HKD2_k127_7091439_1 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 499.0
HKD2_k127_7091439_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 471.0
HKD2_k127_7091439_3 Penicillin binding protein transpeptidase domain K03587,K08384 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 443.0
HKD2_k127_7091439_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 411.0
HKD2_k127_7091439_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 325.0
HKD2_k127_7091439_6 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 310.0
HKD2_k127_7091439_7 Belongs to the MraZ family K03925 - - 0.0000000000000005093 84.0
HKD2_k127_7091439_9 YD repeat-containing protein - - - 0.0000007089 57.0
HKD2_k127_7119016_0 Sulfatase - - - 2.612e-220 693.0
HKD2_k127_7119016_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 516.0
HKD2_k127_7119016_2 unsaturated fatty acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 450.0
HKD2_k127_7119016_3 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 333.0
HKD2_k127_7119016_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000003126 200.0
HKD2_k127_7119016_6 cheY-homologous receiver domain - - - 0.00000000000000000000000001856 112.0
HKD2_k127_7119016_7 - - - - 0.0000000000000000000000001515 109.0
HKD2_k127_7119016_8 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000222 107.0
HKD2_k127_7190670_0 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006945 250.0
HKD2_k127_7190670_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000008243 206.0
HKD2_k127_7190670_2 Methyltransferase domain - - - 0.000000000000742 72.0
HKD2_k127_7190670_3 - - - - 0.0004035 45.0
HKD2_k127_7251353_0 AI-2E family transporter - - - 0.000000000000000001097 98.0
HKD2_k127_7251353_2 - - - - 0.00001182 53.0
HKD2_k127_7396034_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 491.0
HKD2_k127_7396034_1 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 436.0
HKD2_k127_7396034_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 401.0
HKD2_k127_7396034_3 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 330.0
HKD2_k127_7396034_4 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000001112 203.0
HKD2_k127_7526271_0 Protein of unknown function (DUF3376) - - - 6.868e-217 689.0
HKD2_k127_7526271_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 477.0
HKD2_k127_7526271_2 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000004228 224.0
HKD2_k127_7526271_3 MAPEG family - - - 0.000000000000000000000000000000000000004844 149.0
HKD2_k127_7539508_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 384.0
HKD2_k127_7539508_1 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000008215 186.0
HKD2_k127_7660048_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.106e-240 748.0
HKD2_k127_7660048_1 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000006745 171.0
HKD2_k127_7660048_2 - - - - 0.00000000000000000000002516 100.0
HKD2_k127_7660048_3 - - - - 0.000000007211 60.0
HKD2_k127_7670170_0 Selenium-binding protein K17285 - - 1.537e-231 723.0
HKD2_k127_7670170_1 Glycosyltransferase family 9 (heptosyltransferase) K02517,K02843 - 2.3.1.241 1.059e-205 659.0
HKD2_k127_7670170_2 Methyltransferase type 11 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 462.0
HKD2_k127_7670170_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 293.0
HKD2_k127_7670170_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001362 262.0
HKD2_k127_7670170_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000002677 241.0
HKD2_k127_7670170_6 DNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000007525 217.0
HKD2_k127_7670170_7 - - - - 0.000000000000000000000000000000000000000000000000000000004091 207.0
HKD2_k127_7670644_0 Glycosyltransferase like family 2 K07011,K20444 - - 1.517e-194 646.0
HKD2_k127_7670644_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 533.0
HKD2_k127_7670644_2 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
HKD2_k127_7670644_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 310.0
HKD2_k127_7670644_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009223 238.0
HKD2_k127_7670644_5 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000001621 207.0
HKD2_k127_7670644_6 cellulose binding - - - 0.000000000000000000000000000000000000000000005846 165.0
HKD2_k127_7670644_7 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000001079 138.0
HKD2_k127_7670644_8 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000003798 70.0
HKD2_k127_7689841_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 323.0
HKD2_k127_7689841_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 320.0
HKD2_k127_7689841_10 Methyltransferase FkbM domain - - - 0.000000000000000009449 94.0
HKD2_k127_7689841_12 efflux transmembrane transporter activity - - - 0.00000000132 63.0
HKD2_k127_7689841_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 301.0
HKD2_k127_7689841_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
HKD2_k127_7689841_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000001995 163.0
HKD2_k127_7689841_5 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.000000000000000000000000000000000003856 141.0
HKD2_k127_7689841_6 cellulose binding - - - 0.0000000000000000000000000000000306 129.0
HKD2_k127_7689841_7 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000001044 127.0
HKD2_k127_7689841_8 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000003107 128.0
HKD2_k127_7689841_9 response to copper ion K07156,K14166 - - 0.00000000000000000000000003426 112.0
HKD2_k127_7708997_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.904e-307 969.0
HKD2_k127_7708997_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.067e-246 786.0
HKD2_k127_7708997_10 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003457 278.0
HKD2_k127_7708997_11 Protein kinase domain K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000744 280.0
HKD2_k127_7708997_12 SMART ATP-binding region, ATPase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006009 263.0
HKD2_k127_7708997_13 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006867 248.0
HKD2_k127_7708997_14 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009951 246.0
HKD2_k127_7708997_15 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000001686 224.0
HKD2_k127_7708997_16 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000001227 226.0
HKD2_k127_7708997_17 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000003013 218.0
HKD2_k127_7708997_18 Protein of unknown function (DUF520) - - - 0.0000000000000000000000000000000000000000000000000000000006181 205.0
HKD2_k127_7708997_19 PFAM outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000001069 221.0
HKD2_k127_7708997_2 PFAM magnesium chelatase ChlI subunit K07391 - - 7.857e-235 737.0
HKD2_k127_7708997_20 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000005675 187.0
HKD2_k127_7708997_21 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000004324 179.0
HKD2_k127_7708997_22 DNA-templated transcription, initiation - - - 0.00000000000000000000000000000000000000000000001601 181.0
HKD2_k127_7708997_23 HTTM domain protein - - - 0.00000000000000000000000000000000000000000002917 173.0
HKD2_k127_7708997_24 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000003338 168.0
HKD2_k127_7708997_25 Ribosomal protein S21 - - - 0.000000000000000000000002731 102.0
HKD2_k127_7708997_26 Domain of unknown function (DUF5069) - - - 0.0000000000000000000002363 101.0
HKD2_k127_7708997_27 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0001228 47.0
HKD2_k127_7708997_28 - - - - 0.000666 50.0
HKD2_k127_7708997_3 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 1.031e-210 665.0
HKD2_k127_7708997_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 494.0
HKD2_k127_7708997_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 436.0
HKD2_k127_7708997_7 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 384.0
HKD2_k127_7708997_8 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 315.0
HKD2_k127_7708997_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001773 287.0
HKD2_k127_7719843_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 399.0
HKD2_k127_7719843_1 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 375.0
HKD2_k127_7719843_2 Enoyl-CoA hydratase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000005618 231.0
HKD2_k127_7719843_3 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814,K13815 - - 0.000000000000000000007243 93.0
HKD2_k127_7719843_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000002311 61.0
HKD2_k127_7719843_5 transcriptional regulator LuxR K19733 - - 0.00000001086 64.0
HKD2_k127_7719843_6 response regulator K07782,K15852 - - 0.0000004301 54.0
HKD2_k127_7754877_0 cellulose binding - - - 6.25e-196 613.0
HKD2_k127_7754877_1 Calcium Proton K07300 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015079,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015386,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022821,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035725,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0099516,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 382.0
HKD2_k127_7754877_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000000000000000007523 148.0
HKD2_k127_7754877_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000495 142.0
HKD2_k127_7754877_4 - - - - 0.00000000000000003176 85.0
HKD2_k127_7754877_7 - - - - 0.00000002535 55.0
HKD2_k127_7754877_8 - - - - 0.00000002863 58.0
HKD2_k127_7780243_0 elongation factor Tu domain 2 protein K06207 - - 1.691e-293 912.0
HKD2_k127_7780243_1 beta-keto acid cleavage enzyme - - - 7.804e-225 699.0
HKD2_k127_7780243_10 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000001433 183.0
HKD2_k127_7780243_12 - - - - 0.0000000000000000000000000002613 121.0
HKD2_k127_7780243_14 - - - - 0.0000000001432 71.0
HKD2_k127_7780243_2 regulation of DNA-templated transcription, elongation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 608.0
HKD2_k127_7780243_3 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 347.0
HKD2_k127_7780243_4 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 289.0
HKD2_k127_7780243_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004975 258.0
HKD2_k127_7780243_6 Hydrogen peroxide-inducible genes activator K04761,K11921 - - 0.00000000000000000000000000000000000000000000000000000000001239 218.0
HKD2_k127_7780243_7 - - - - 0.0000000000000000000000000000000000000000000000000000000005938 211.0
HKD2_k127_7780243_8 Nuclear protein SET K07117 - - 0.00000000000000000000000000000000000000000000000004183 182.0
HKD2_k127_7780243_9 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000009402 183.0
HKD2_k127_7791605_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 4.376e-241 755.0
HKD2_k127_7791605_1 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 473.0
HKD2_k127_7791605_10 LexA DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000009276 221.0
HKD2_k127_7791605_11 Addiction module toxin, RelE StbE family - - - 0.000000000000000000000000000000000000000000000000006684 182.0
HKD2_k127_7791605_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000004574 182.0
HKD2_k127_7791605_13 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000008305 169.0
HKD2_k127_7791605_14 Glycoprotease family - - - 0.0000000000000000000000000000000000000000005226 164.0
HKD2_k127_7791605_15 protein trimerization - - - 0.00000000000000000000000000000000000001446 155.0
HKD2_k127_7791605_16 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000004054 145.0
HKD2_k127_7791605_17 membrane - - - 0.0000000000000000000000000000000000136 151.0
HKD2_k127_7791605_18 Ribosomal protein S18 K02963 - - 0.00000000000000000000000000000000007694 134.0
HKD2_k127_7791605_19 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000000000000000000000508 134.0
HKD2_k127_7791605_2 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 345.0
HKD2_k127_7791605_20 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000000000000002443 134.0
HKD2_k127_7791605_21 Ribosomal protein L33 K02913 - - 0.000000000000000001245 86.0
HKD2_k127_7791605_22 impB/mucB/samB family K14161 - - 0.0000000000000000502 88.0
HKD2_k127_7791605_23 TIGRFAM Glutaredoxin-like protein, YruB-family - - - 0.000000003175 61.0
HKD2_k127_7791605_24 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000003669 55.0
HKD2_k127_7791605_25 CAAX protease self-immunity - - - 0.000001591 59.0
HKD2_k127_7791605_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 340.0
HKD2_k127_7791605_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 334.0
HKD2_k127_7791605_5 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 292.0
HKD2_k127_7791605_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008636 286.0
HKD2_k127_7791605_7 Domain of unknown function (DUF4071) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007624 246.0
HKD2_k127_7791605_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 239.0
HKD2_k127_7791605_9 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000008044 229.0
HKD2_k127_7830516_0 Pyridine nucleotide-disulphide oxidoreductase - - - 1.895e-254 789.0
HKD2_k127_7830516_1 Aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 527.0
HKD2_k127_7830516_10 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006989 237.0
HKD2_k127_7830516_11 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000007323 242.0
HKD2_k127_7830516_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001181 248.0
HKD2_k127_7830516_13 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000006505 194.0
HKD2_k127_7830516_14 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000006972 165.0
HKD2_k127_7830516_15 PFAM Abortive infection protein K07052 - - 0.00000000000000000000000000000000000000002648 161.0
HKD2_k127_7830516_16 MerR, DNA binding K13639 - - 0.000000000000000000000005373 108.0
HKD2_k127_7830516_17 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000004399 89.0
HKD2_k127_7830516_18 PFAM transcription elongation factor GreA GreB - - - 0.0000000000004056 73.0
HKD2_k127_7830516_19 Cupin 2, conserved barrel domain protein - - - 0.000000134 56.0
HKD2_k127_7830516_2 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 482.0
HKD2_k127_7830516_20 - - - - 0.0003912 43.0
HKD2_k127_7830516_3 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 463.0
HKD2_k127_7830516_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 376.0
HKD2_k127_7830516_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 366.0
HKD2_k127_7830516_6 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 371.0
HKD2_k127_7830516_7 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 376.0
HKD2_k127_7830516_8 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 351.0
HKD2_k127_7830516_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001218 268.0
HKD2_k127_7850240_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.137e-209 659.0
HKD2_k127_7850240_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 573.0
HKD2_k127_7850240_10 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000003249 206.0
HKD2_k127_7850240_11 3D domain - - - 0.000000000000000000000000000000000000000000000003123 182.0
HKD2_k127_7850240_12 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000007946 134.0
HKD2_k127_7850240_13 Nitrous oxide reductase K00376 - 1.7.2.4 0.0000000000000001699 81.0
HKD2_k127_7850240_14 O-methyltransferase K00588 - 2.1.1.104 0.00000001126 66.0
HKD2_k127_7850240_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 551.0
HKD2_k127_7850240_3 glutamate-cysteine ligase activity K06048 GO:0003674,GO:0003824,GO:0016874,GO:0016879 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 475.0
HKD2_k127_7850240_4 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 411.0
HKD2_k127_7850240_5 glutamate-cysteine ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 396.0
HKD2_k127_7850240_6 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 383.0
HKD2_k127_7850240_7 Multicopper oxidase K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 386.0
HKD2_k127_7850240_8 TIGRFAM SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005907 239.0
HKD2_k127_7850240_9 Copper binding periplasmic protein CusF K07152 - - 0.00000000000000000000000000000000000000000000000000000000000003378 225.0
HKD2_k127_789533_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 375.0
HKD2_k127_789533_1 Transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 379.0
HKD2_k127_789533_10 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000005813 115.0
HKD2_k127_789533_13 - - - - 0.000000000000005853 82.0
HKD2_k127_789533_2 Peptidogalycan biosysnthesis/recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 361.0
HKD2_k127_789533_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 328.0
HKD2_k127_789533_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 298.0
HKD2_k127_789533_5 Small-conductance mechanosensitive channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006512 256.0
HKD2_k127_789533_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003265 259.0
HKD2_k127_789533_7 Small integral membrane protein - - - 0.0000000000000000000000000000000000000009418 153.0
HKD2_k127_789533_8 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000008859 150.0
HKD2_k127_789533_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000005968 123.0
HKD2_k127_7901460_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 325.0
HKD2_k127_7901460_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 324.0
HKD2_k127_7901460_2 PFAM permease YjgP YjgQ family protein K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002489 289.0
HKD2_k127_7901460_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001693 243.0
HKD2_k127_7901460_4 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000886 182.0
HKD2_k127_7901460_5 - - - - 0.000000000000000000000000000000000000000000000004369 177.0
HKD2_k127_7901460_6 SMART helicase c2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000002281 169.0
HKD2_k127_7901460_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000003229 104.0
HKD2_k127_7901460_8 - - - - 0.00000000000002637 75.0
HKD2_k127_7991988_0 Cytochrome C oxidase subunit I K02274 - 1.9.3.1 1.108e-205 654.0
HKD2_k127_7991988_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 361.0
HKD2_k127_7991988_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 301.0
HKD2_k127_7991988_3 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001948 265.0
HKD2_k127_7991988_4 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000000000007959 179.0
HKD2_k127_7991988_5 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000001014 89.0
HKD2_k127_7991988_6 signal sequence binding K07152 - - 0.00000000000000004143 90.0
HKD2_k127_7991988_7 Cytochrome c K02275,K17223 - 1.9.3.1 0.000000000000001515 87.0
HKD2_k127_7991988_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000002848 56.0
HKD2_k127_7992409_0 Alpha beta hydrolase K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 451.0
HKD2_k127_7992409_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 421.0
HKD2_k127_7992409_2 Protein of unknown function (DUF1348) K09958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 300.0
HKD2_k127_7992409_3 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 285.0
HKD2_k127_7992409_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008633 263.0
HKD2_k127_7992409_5 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000007185 220.0
HKD2_k127_7992409_6 - - - - 0.000000000000000003509 87.0
HKD2_k127_7992409_7 - - - - 0.00008419 48.0
HKD2_k127_8030108_0 Tricorn protease C1 domain K08676 - - 9.775e-307 964.0
HKD2_k127_8030108_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 548.0
HKD2_k127_8030108_2 isochorismatase hydrolase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001442 235.0
HKD2_k127_8030581_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 443.0
HKD2_k127_8030581_1 ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 412.0
HKD2_k127_8030581_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 385.0
HKD2_k127_8030581_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 383.0
HKD2_k127_8030581_4 Protein of unknown function (DUF1460) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 377.0
HKD2_k127_8030581_5 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000003117 179.0
HKD2_k127_8030581_6 - - - - 0.00000000000000000000000000000000000007188 159.0
HKD2_k127_8030581_7 polysaccharide biosynthetic process - - - 0.000000000000000000006441 105.0
HKD2_k127_8030581_8 Transcriptional regulator - - - 0.0000000000000000007138 89.0
HKD2_k127_8056712_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 subunit K00164 - 1.2.4.2 1.221e-209 664.0
HKD2_k127_8056712_1 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 436.0
HKD2_k127_8056712_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 363.0
HKD2_k127_8056712_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000006206 213.0
HKD2_k127_8056712_4 ABC-type uncharacterized transport system - - - 0.00000000000000000003989 93.0
HKD2_k127_8118149_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 401.0
HKD2_k127_8118149_1 PFAM Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004388 280.0
HKD2_k127_8118149_2 rieske 2fe-2s - - - 0.0000000000000000000001108 103.0
HKD2_k127_8118149_3 Animal haem peroxidase - - - 0.00000000000138 74.0
HKD2_k127_8128026_0 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 355.0
HKD2_k127_8128026_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003025 238.0
HKD2_k127_8128026_2 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000709 239.0
HKD2_k127_8137307_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 618.0
HKD2_k127_8137307_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 511.0
HKD2_k127_8137307_2 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 414.0
HKD2_k127_8137307_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.00000000000000000003645 91.0
HKD2_k127_8240597_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.046e-201 638.0
HKD2_k127_8240597_1 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 428.0
HKD2_k127_8240597_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 322.0
HKD2_k127_8240597_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 319.0
HKD2_k127_8240597_4 - - - - 0.0000000000000000000000000000000000000000127 159.0
HKD2_k127_8244994_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 309.0
HKD2_k127_8244994_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
HKD2_k127_8244994_2 DNA-templated transcription, initiation - - - 0.000000000000000000000000000000000000000000000000000000008299 207.0
HKD2_k127_8244994_3 Transposase - - - 0.00000000000000000000000000000000000000000000000001389 186.0
HKD2_k127_8244994_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000006791 182.0
HKD2_k127_8244994_5 FecR protein - - - 0.00000001193 65.0
HKD2_k127_8275043_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.193e-303 942.0
HKD2_k127_8275043_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.08e-233 732.0
HKD2_k127_8275043_10 - - - - 0.00000000000000001452 90.0
HKD2_k127_8275043_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 557.0
HKD2_k127_8275043_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 291.0
HKD2_k127_8275043_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000003981 201.0
HKD2_k127_8275043_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000001888 211.0
HKD2_k127_8275043_6 - - - - 0.000000000000000000000000000000000000000003052 162.0
HKD2_k127_8275043_7 aminotransferase class I and II - - - 0.000000000000000000000000000000000000001893 150.0
HKD2_k127_8275043_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000006973 130.0
HKD2_k127_8275043_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000002153 123.0
HKD2_k127_8283608_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.823e-231 727.0
HKD2_k127_8283608_1 Flavin containing amine oxidoreductase - - - 5.757e-226 709.0
HKD2_k127_8283608_10 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003879 459.0
HKD2_k127_8283608_11 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 461.0
HKD2_k127_8283608_12 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 469.0
HKD2_k127_8283608_13 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 436.0
HKD2_k127_8283608_14 Proton-conducting membrane transporter K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 426.0
HKD2_k127_8283608_15 Alkaline phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 413.0
HKD2_k127_8283608_16 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 420.0
HKD2_k127_8283608_17 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 391.0
HKD2_k127_8283608_18 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 395.0
HKD2_k127_8283608_19 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 383.0
HKD2_k127_8283608_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 1.171e-207 653.0
HKD2_k127_8283608_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 310.0
HKD2_k127_8283608_21 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009137 270.0
HKD2_k127_8283608_22 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000002395 243.0
HKD2_k127_8283608_23 - - - - 0.000000000000000000000000000000000000000000000004866 182.0
HKD2_k127_8283608_24 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000434 184.0
HKD2_k127_8283608_25 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000122 168.0
HKD2_k127_8283608_26 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.00000000000000000000000000009724 121.0
HKD2_k127_8283608_27 Tetratricopeptide repeat - - - 0.000000000000000000000000004698 122.0
HKD2_k127_8283608_28 - - - - 0.00000000000002392 85.0
HKD2_k127_8283608_29 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000009469 71.0
HKD2_k127_8283608_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.238e-206 662.0
HKD2_k127_8283608_30 Tetratricopeptide TPR_2 repeat protein - - - 0.00007702 57.0
HKD2_k127_8283608_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 9.103e-205 644.0
HKD2_k127_8283608_5 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.496e-201 652.0
HKD2_k127_8283608_6 PFAM peptidase M29 aminopeptidase II K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 535.0
HKD2_k127_8283608_7 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 523.0
HKD2_k127_8283608_8 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 522.0
HKD2_k127_8283608_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 486.0
HKD2_k127_8317262_0 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 286.0
HKD2_k127_8317262_1 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000001591 214.0
HKD2_k127_8317262_2 response to heat K07090 - - 0.00000000000000000000000000000002694 136.0
HKD2_k127_8317262_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000000000000001669 122.0
HKD2_k127_8317262_4 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.00000000000000000000000009797 110.0
HKD2_k127_8317262_5 Cation transport ATPase K17686 - 3.6.3.54 0.00000057 53.0
HKD2_k127_8317262_6 - - - - 0.000000725 55.0
HKD2_k127_8317262_7 - - - - 0.000002182 57.0
HKD2_k127_8357247_0 HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000478 284.0
HKD2_k127_8357247_1 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000001594 235.0
HKD2_k127_8357247_2 GTP cyclohydrolase I K00950,K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008616,GO:0009058,GO:0009108,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0019752,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0042455,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659 2.7.6.3,3.5.4.16 0.0000000000000000000000000000000000000000000000000000000001591 211.0
HKD2_k127_8357247_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000001437 189.0
HKD2_k127_8357247_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001987 162.0
HKD2_k127_8357247_5 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000003057 157.0
HKD2_k127_8357247_6 DoxX - - - 0.000000000000000000001319 98.0
HKD2_k127_8357247_7 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000006019 100.0
HKD2_k127_83740_0 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000001851 170.0
HKD2_k127_83740_2 EamA-like transporter family - - - 0.000000000001666 68.0
HKD2_k127_83740_3 surface antigen - - - 0.000000007917 63.0
HKD2_k127_8383195_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2428.0
HKD2_k127_8383195_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.076e-264 825.0
HKD2_k127_8383195_10 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 343.0
HKD2_k127_8383195_11 Fungal chitosanase of glycosyl hydrolase group 75 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 338.0
HKD2_k127_8383195_12 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 306.0
HKD2_k127_8383195_13 Oxidoreductase molybdopterin binding domain K00387,K07147 - 1.8.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 305.0
HKD2_k127_8383195_14 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 275.0
HKD2_k127_8383195_15 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004755 246.0
HKD2_k127_8383195_16 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000004506 237.0
HKD2_k127_8383195_17 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
HKD2_k127_8383195_18 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000001931 214.0
HKD2_k127_8383195_19 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K02849,K12982 - - 0.00000000000000000000000000000000000000000000000000000000009953 218.0
HKD2_k127_8383195_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.933e-242 772.0
HKD2_k127_8383195_20 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000002809 162.0
HKD2_k127_8383195_21 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000006683 149.0
HKD2_k127_8383195_22 Rhomboid family - - - 0.0000000000000000000000000000000000001856 152.0
HKD2_k127_8383195_23 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000001001 136.0
HKD2_k127_8383195_24 - - - - 0.000000000000000000000000000000000468 151.0
HKD2_k127_8383195_25 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000001159 134.0
HKD2_k127_8383195_27 Transmembrane proteins 14C - - - 0.0000000007199 64.0
HKD2_k127_8383195_28 Evidence 5 No homology to any previously reported sequences K14194,K21449 - - 0.00000005551 66.0
HKD2_k127_8383195_3 DNA polymerase X family K02347 - - 2.093e-227 721.0
HKD2_k127_8383195_4 Fumarase C C-terminus - - - 2.152e-199 634.0
HKD2_k127_8383195_5 PFAM NAD-dependent epimerase dehydratase K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 550.0
HKD2_k127_8383195_6 PFAM LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 352.0
HKD2_k127_8383195_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 344.0
HKD2_k127_8383195_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 345.0
HKD2_k127_8383195_9 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 338.0
HKD2_k127_8577352_0 Beta-eliminating lyase K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 462.0
HKD2_k127_8577352_1 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
HKD2_k127_8577352_10 CDP-alcohol phosphatidyltransferase K07281,K07291 - 2.7.7.74,2.7.8.34 0.000000000000009534 83.0
HKD2_k127_8577352_11 Protein of unknown function (DUF2723) - - - 0.0000000000001098 84.0
HKD2_k127_8577352_12 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000003495 79.0
HKD2_k127_8577352_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 376.0
HKD2_k127_8577352_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 331.0
HKD2_k127_8577352_4 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001578 241.0
HKD2_k127_8577352_5 CDP-alcohol phosphatidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000005791 228.0
HKD2_k127_8577352_6 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000213 205.0
HKD2_k127_8577352_7 Nucleotidyl transferase K07281 - 2.7.7.74 0.00000000000000000000000000000000000000000006507 172.0
HKD2_k127_8577352_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000001312 164.0
HKD2_k127_8577352_9 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000236 123.0
HKD2_k127_8765319_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1425.0
HKD2_k127_8765319_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 8.328e-255 799.0
HKD2_k127_8765319_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 391.0
HKD2_k127_8765319_3 glycosyl transferase family 2 - - - 0.000000000000007134 79.0
HKD2_k127_8765319_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000009521 66.0
HKD2_k127_87676_0 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 536.0
HKD2_k127_87676_1 antibiotic catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002462 271.0
HKD2_k127_87676_2 Conserved repeat domain - - - 0.000000000000000000000000005484 128.0
HKD2_k127_87676_3 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.000000000000000000000002001 121.0
HKD2_k127_87676_4 Conserved repeat domain - - - 0.000000000000000000000002155 117.0
HKD2_k127_87676_5 Galactose oxidase, central domain - - - 0.00000000000000000009885 105.0
HKD2_k127_87676_6 Belongs to the glycosyl hydrolase 18 family - - - 0.0000001413 65.0
HKD2_k127_8975615_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1190.0
HKD2_k127_8975615_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 2.334e-263 841.0
HKD2_k127_8975615_10 Belongs to the universal stress protein A family - - - 0.000000000000000001235 94.0
HKD2_k127_8975615_11 NlpC/P60 family - - - 0.0000000002496 72.0
HKD2_k127_8975615_2 FtsX-like permease family K02004 - - 2.556e-235 752.0
HKD2_k127_8975615_3 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 359.0
HKD2_k127_8975615_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 359.0
HKD2_k127_8975615_5 Efflux transporter, RND family, MFP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 321.0
HKD2_k127_8975615_6 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000003333 183.0
HKD2_k127_8975615_7 Haem-binding domain - - - 0.000000000000000000000000000000000000001263 152.0
HKD2_k127_8975615_8 - - - - 0.000000000000000000000000000000000000001634 151.0
HKD2_k127_8975615_9 Universal stress protein family - - - 0.000000000000000000000000000000000000004364 157.0
HKD2_k127_9027412_0 Sortilin, neurotensin receptor 3, - - - 0.0 1301.0
HKD2_k127_9027412_1 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 376.0
HKD2_k127_9027412_10 - - - - 0.000000000000000000000000000002337 127.0
HKD2_k127_9027412_12 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000006684 90.0
HKD2_k127_9027412_15 General secretion pathway protein K02459 - - 0.0000003097 60.0
HKD2_k127_9027412_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 364.0
HKD2_k127_9027412_3 Nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 338.0
HKD2_k127_9027412_4 Type II secretion system (T2SS), protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000157 267.0
HKD2_k127_9027412_7 Type II secretion system (T2SS), protein K - - - 0.000000000000000000000000000000000000002203 159.0
HKD2_k127_9027412_8 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000005323 138.0
HKD2_k127_9027412_9 Methyltransferase domain - - - 0.000000000000000000000000000000006258 140.0
HKD2_k127_9063464_0 PFAM cytochrome c assembly protein - - - 3.844e-199 640.0
HKD2_k127_9063464_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 461.0
HKD2_k127_9063464_2 ResB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 381.0
HKD2_k127_9063464_3 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000001359 199.0
HKD2_k127_9063464_5 - - - - 0.00000000000000000000000000000000000507 151.0
HKD2_k127_9063464_6 Cytochrome c - - - 0.00000000000000009476 84.0
HKD2_k127_9063464_7 Cytochrome c - - - 0.000000000000004097 80.0
HKD2_k127_9074572_0 - - - - 0.0000000000000000000000000000000000000000001542 164.0
HKD2_k127_9074572_1 - - - - 0.00000000000000004038 91.0
HKD2_k127_9074572_2 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07264 - 2.4.2.43 0.00002112 55.0
HKD2_k127_9078178_0 amino acid - - - 6.676e-237 748.0
HKD2_k127_9078178_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 3.799e-228 717.0
HKD2_k127_9078178_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 351.0
HKD2_k127_9078178_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 360.0
HKD2_k127_9078178_4 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005238 256.0
HKD2_k127_9078178_5 Transglycosylase associated protein - - - 0.0000000000000000000001896 98.0
HKD2_k127_9086249_0 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 569.0
HKD2_k127_9086249_1 Endonuclease containing a URI domain K07461 - - 0.000000000000000000000000009582 111.0
HKD2_k127_9086249_2 - - - - 0.0003476 48.0
HKD2_k127_9087082_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1699.0
HKD2_k127_9087082_1 PA domain - - - 1.819e-313 976.0
HKD2_k127_9087082_10 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
HKD2_k127_9087082_11 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000001014 189.0
HKD2_k127_9087082_2 Aldehyde dehydrogenase family - - - 1.324e-236 740.0
HKD2_k127_9087082_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 502.0
HKD2_k127_9087082_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 475.0
HKD2_k127_9087082_5 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 490.0
HKD2_k127_9087082_6 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 436.0
HKD2_k127_9087082_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 382.0
HKD2_k127_9087082_8 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 384.0
HKD2_k127_9087082_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 371.0
HKD2_k127_9102350_0 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 368.0
HKD2_k127_9102350_1 NADPH:quinone reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 367.0
HKD2_k127_9102350_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 364.0
HKD2_k127_9102350_3 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 314.0
HKD2_k127_9102350_4 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000000000000000001515 227.0
HKD2_k127_9102350_5 - - - - 0.00000000000000000000000000000000000000000001415 168.0
HKD2_k127_9102350_6 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000025 165.0
HKD2_k127_9102350_7 acetyltransferase K09994 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019634,GO:0019637,GO:0033051,GO:0044237,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000001041 144.0
HKD2_k127_9126397_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000003208 148.0
HKD2_k127_9126397_1 Putative ParB-like nuclease - - - 0.000000000000000000000000000000000002796 138.0
HKD2_k127_9126397_3 Protein of unknown function (DUF3096) - - - 0.000001373 50.0
HKD2_k127_9128388_0 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 337.0
HKD2_k127_9128388_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005238 233.0
HKD2_k127_9128388_2 Ion channel - - - 0.0000000000000000000000000123 120.0
HKD2_k127_9128388_4 Tetratricopeptide repeat - - - 0.00005475 52.0
HKD2_k127_9131407_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.258e-306 955.0
HKD2_k127_9131407_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 4.916e-255 800.0
HKD2_k127_9131407_10 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 439.0
HKD2_k127_9131407_11 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 412.0
HKD2_k127_9131407_12 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 417.0
HKD2_k127_9131407_13 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 403.0
HKD2_k127_9131407_14 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 389.0
HKD2_k127_9131407_15 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 367.0
HKD2_k127_9131407_16 Proteasome subunit K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 359.0
HKD2_k127_9131407_17 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 361.0
HKD2_k127_9131407_18 Proteasome subunit K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
HKD2_k127_9131407_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 307.0
HKD2_k127_9131407_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.867e-249 779.0
HKD2_k127_9131407_20 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.000000000000000000000000000000000000000000000000000000000000000000000000000000181 278.0
HKD2_k127_9131407_21 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000003504 248.0
HKD2_k127_9131407_22 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000006143 240.0
HKD2_k127_9131407_23 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000169 230.0
HKD2_k127_9131407_24 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000006318 227.0
HKD2_k127_9131407_25 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000001404 215.0
HKD2_k127_9131407_26 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000001761 207.0
HKD2_k127_9131407_27 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000001671 198.0
HKD2_k127_9131407_28 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000002709 184.0
HKD2_k127_9131407_29 Ami_3 - - - 0.00000000000000000000000000000000000000000000004835 179.0
HKD2_k127_9131407_3 ABC transporter transmembrane region K06147 - - 1.754e-242 765.0
HKD2_k127_9131407_30 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000009925 173.0
HKD2_k127_9131407_31 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000000001718 176.0
HKD2_k127_9131407_32 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000009033 172.0
HKD2_k127_9131407_33 - - - - 0.0000000000000000000000000000000000000000008463 162.0
HKD2_k127_9131407_34 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000001647 138.0
HKD2_k127_9131407_35 ACT domain - - - 0.000000000000000000000000000000004329 134.0
HKD2_k127_9131407_36 - - - - 0.00000000000000000000000000000002975 131.0
HKD2_k127_9131407_37 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000008415 122.0
HKD2_k127_9131407_38 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.0000000000000000000000001401 107.0
HKD2_k127_9131407_39 Belongs to the UPF0761 family K07058 - - 0.0000000000000000000000003597 116.0
HKD2_k127_9131407_4 Outer membrane protein assembly complex, YaeT protein K07277 - - 9.863e-195 632.0
HKD2_k127_9131407_40 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000004287 107.0
HKD2_k127_9131407_42 Aspartyl protease - - - 0.0000000001294 74.0
HKD2_k127_9131407_43 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 GO:0003674,GO:0003824,GO:0004150,GO:0005488,GO:0005515,GO:0016829,GO:0016830,GO:0016832,GO:0042802 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000141 66.0
HKD2_k127_9131407_45 Domain of unknown function (DUF4912) K09942 - - 0.0000001274 62.0
HKD2_k127_9131407_5 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 595.0
HKD2_k127_9131407_6 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 546.0
HKD2_k127_9131407_7 - K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 535.0
HKD2_k127_9131407_8 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 488.0
HKD2_k127_9131407_9 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 462.0
HKD2_k127_9152813_0 Glycosyl transferase family 21 - - - 1.81e-254 801.0
HKD2_k127_9152813_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 426.0
HKD2_k127_9163306_0 DNA topoisomerase III K03169 - 5.99.1.2 5.442e-288 913.0
HKD2_k127_9163306_1 MacB-like periplasmic core domain - - - 1.851e-283 894.0
HKD2_k127_9163306_10 unsaturated fatty acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 437.0
HKD2_k127_9163306_11 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 417.0
HKD2_k127_9163306_12 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 409.0
HKD2_k127_9163306_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 334.0
HKD2_k127_9163306_14 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 333.0
HKD2_k127_9163306_15 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
HKD2_k127_9163306_16 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008636 269.0
HKD2_k127_9163306_17 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001592 261.0
HKD2_k127_9163306_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004034 261.0
HKD2_k127_9163306_19 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004921 265.0
HKD2_k127_9163306_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 6.667e-279 867.0
HKD2_k127_9163306_20 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007872 247.0
HKD2_k127_9163306_21 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002231 244.0
HKD2_k127_9163306_22 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003154 243.0
HKD2_k127_9163306_23 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000007629 222.0
HKD2_k127_9163306_24 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000002331 216.0
HKD2_k127_9163306_25 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000206 194.0
HKD2_k127_9163306_26 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000001497 191.0
HKD2_k127_9163306_27 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000001178 186.0
HKD2_k127_9163306_28 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000002531 180.0
HKD2_k127_9163306_29 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000000003299 177.0
HKD2_k127_9163306_3 aminopeptidase N K01256 - 3.4.11.2 1.24e-270 859.0
HKD2_k127_9163306_30 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000399 172.0
HKD2_k127_9163306_31 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.0000000000000000000000000000000000000001076 155.0
HKD2_k127_9163306_33 - - - - 0.0000000000000000000000000000003694 126.0
HKD2_k127_9163306_34 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000668 121.0
HKD2_k127_9163306_35 EamA-like transporter family - - - 0.000000000000000000000000008567 123.0
HKD2_k127_9163306_36 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000001051 101.0
HKD2_k127_9163306_37 - - - - 0.000000000000000000001014 100.0
HKD2_k127_9163306_38 PAS fold K02491 - 2.7.13.3 0.00000000000000000009039 105.0
HKD2_k127_9163306_39 - - - - 0.0000000000000000001167 92.0
HKD2_k127_9163306_4 ABC transporter - - - 2.949e-214 682.0
HKD2_k127_9163306_40 Ribosomal protein L34 K02914 - - 0.0000000000000000001204 90.0
HKD2_k127_9163306_41 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000002553 92.0
HKD2_k127_9163306_42 - - - - 0.00000000000000006106 84.0
HKD2_k127_9163306_44 Ribosomal protein L35 K02916 - - 0.0000000000004377 74.0
HKD2_k127_9163306_45 helix_turn_helix, Lux Regulon K07684 - - 0.00000000004759 74.0
HKD2_k127_9163306_48 Putative peptidoglycan binding domain - - - 0.0000007804 61.0
HKD2_k127_9163306_5 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 2.77e-199 629.0
HKD2_k127_9163306_6 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 501.0
HKD2_k127_9163306_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 498.0
HKD2_k127_9163306_8 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 477.0
HKD2_k127_9163306_9 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 468.0
HKD2_k127_9200945_0 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 328.0
HKD2_k127_9200945_1 Two component transcriptional regulator, winged helix family K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 295.0
HKD2_k127_9200945_2 PFAM ATP-binding region ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000006961 175.0
HKD2_k127_9200945_3 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000003534 139.0
HKD2_k127_9205179_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 359.0
HKD2_k127_9205179_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 327.0
HKD2_k127_9205179_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 321.0
HKD2_k127_9205179_3 Dihydrodipicolinate reductase, N-terminus K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000018 232.0
HKD2_k127_9205179_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000009789 226.0
HKD2_k127_9205179_5 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000001923 169.0
HKD2_k127_9205179_6 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000009351 165.0
HKD2_k127_9205179_7 general secretion pathway protein - - - 0.0000000000000000000000000000003652 130.0
HKD2_k127_9205179_8 OmpA family - - - 0.000000000000000000000000004896 123.0
HKD2_k127_9241425_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.33e-253 802.0
HKD2_k127_9241425_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.238e-199 628.0
HKD2_k127_9241425_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001151 280.0
HKD2_k127_9241425_11 MazG nucleotide pyrophosphohydrolase domain K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000005315 265.0
HKD2_k127_9241425_12 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000007474 241.0
HKD2_k127_9241425_13 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
HKD2_k127_9241425_14 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000001657 212.0
HKD2_k127_9241425_15 Response regulator, receiver K02657,K20972 - - 0.00000000000000000000000000000009827 137.0
HKD2_k127_9241425_16 ribosomal protein L31 K02909 - - 0.0000000000000000000000000000005866 122.0
HKD2_k127_9241425_17 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000003996 119.0
HKD2_k127_9241425_18 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000006715 102.0
HKD2_k127_9241425_19 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000001269 94.0
HKD2_k127_9241425_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 572.0
HKD2_k127_9241425_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 475.0
HKD2_k127_9241425_4 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 460.0
HKD2_k127_9241425_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 394.0
HKD2_k127_9241425_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
HKD2_k127_9241425_7 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 311.0
HKD2_k127_9241425_8 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 308.0
HKD2_k127_9241425_9 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 293.0
HKD2_k127_9263798_0 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1407.0
HKD2_k127_9263798_1 transporter, ATP-binding protein K13926 - - 0.0 1214.0
HKD2_k127_9263798_10 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000271 254.0
HKD2_k127_9263798_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 2.201e-291 910.0
HKD2_k127_9263798_3 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 3.406e-221 694.0
HKD2_k127_9263798_4 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 491.0
HKD2_k127_9263798_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 381.0
HKD2_k127_9263798_6 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 340.0
HKD2_k127_9263798_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 304.0
HKD2_k127_9263798_8 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 307.0
HKD2_k127_9263798_9 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 269.0
HKD2_k127_9264358_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.593e-300 951.0
HKD2_k127_9264358_1 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 3.097e-285 889.0
HKD2_k127_9264358_10 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 456.0
HKD2_k127_9264358_11 Metal dependent phosphohydrolases with conserved 'HD' motif. K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 401.0
HKD2_k127_9264358_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 407.0
HKD2_k127_9264358_13 metalloendopeptidase activity K01392,K01414 - 3.4.24.15,3.4.24.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 409.0
HKD2_k127_9264358_14 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 329.0
HKD2_k127_9264358_15 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 319.0
HKD2_k127_9264358_16 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 312.0
HKD2_k127_9264358_17 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 309.0
HKD2_k127_9264358_18 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001045 281.0
HKD2_k127_9264358_2 Lipase maturation factor - - - 3.492e-222 698.0
HKD2_k127_9264358_20 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000002099 241.0
HKD2_k127_9264358_21 HemY protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008443 252.0
HKD2_k127_9264358_22 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000003118 229.0
HKD2_k127_9264358_23 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.00000000000000000000000000000000000000000000000000000000000004405 223.0
HKD2_k127_9264358_24 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000006525 218.0
HKD2_k127_9264358_25 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000008136 207.0
HKD2_k127_9264358_26 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000004762 224.0
HKD2_k127_9264358_27 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000768 217.0
HKD2_k127_9264358_28 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000004351 195.0
HKD2_k127_9264358_29 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000009066 190.0
HKD2_k127_9264358_3 Domain of unknown function (DUF3463) - - - 1.558e-214 674.0
HKD2_k127_9264358_30 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000000000000000000000000000000008552 178.0
HKD2_k127_9264358_31 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000001371 175.0
HKD2_k127_9264358_32 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000001305 174.0
HKD2_k127_9264358_33 Putative molybdenum carrier - - - 0.000000000000000000000000000000000001685 146.0
HKD2_k127_9264358_34 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000001541 138.0
HKD2_k127_9264358_35 Dodecin K09165 - - 0.00000000000000000000000001007 112.0
HKD2_k127_9264358_36 Cyclic phosphodiesterase-like - - - 0.00000000000000000000000006002 113.0
HKD2_k127_9264358_37 - - - - 0.00000000000000000000000153 108.0
HKD2_k127_9264358_38 CHAD - - - 0.000000000000000000003011 99.0
HKD2_k127_9264358_39 - - - - 0.0000000000000000001944 90.0
HKD2_k127_9264358_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 1.958e-199 628.0
HKD2_k127_9264358_41 - - - - 0.00000000000000005309 83.0
HKD2_k127_9264358_42 - - - - 0.00000000008063 70.0
HKD2_k127_9264358_45 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.0008714 46.0
HKD2_k127_9264358_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 490.0
HKD2_k127_9264358_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 475.0
HKD2_k127_9264358_7 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 460.0
HKD2_k127_9264358_8 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 447.0
HKD2_k127_9264358_9 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 449.0
HKD2_k127_9264928_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 463.0
HKD2_k127_9264928_1 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001269 266.0
HKD2_k127_9264928_2 - - - - 0.000000000000000000000000000000000000000000000000000001353 194.0
HKD2_k127_9264928_3 Hep Hag repeat protein - GO:0005575,GO:0005576 - 0.000000000000000000000000000000000000000000000000000004113 206.0
HKD2_k127_9264928_4 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000001195 148.0
HKD2_k127_9264928_5 Thioredoxin-like - - - 0.0000000000000000000000000000000001266 147.0
HKD2_k127_9264928_6 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000005464 127.0
HKD2_k127_9264928_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000002066 61.0
HKD2_k127_9264928_8 Tetratricopeptide repeat - - - 0.0000005097 53.0
HKD2_k127_9268870_0 ATP-dependent DNA helicase activity K16898 - 3.6.4.12 2.193e-270 867.0
HKD2_k127_9268870_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 539.0
HKD2_k127_9268870_3 selenocysteine insertion sequence binding K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 427.0
HKD2_k127_9268870_4 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 407.0
HKD2_k127_9268870_5 selenide, water dikinase activity K01008,K04487 - 2.7.9.3,2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 301.0
HKD2_k127_9268870_6 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000001877 167.0
HKD2_k127_9268870_7 PFAM outer membrane efflux protein - - - 0.0000000001141 74.0
HKD2_k127_9273811_0 RecF/RecN/SMC N terminal domain K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 568.0
HKD2_k127_9273811_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 547.0
HKD2_k127_9273811_10 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000002963 164.0
HKD2_k127_9273811_11 - - - - 0.0000000000000000000003816 102.0
HKD2_k127_9273811_12 - - - - 0.0003797 46.0
HKD2_k127_9273811_2 Pyridine nucleotide-disulphide oxidoreductase K00362,K07001 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 452.0
HKD2_k127_9273811_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 365.0
HKD2_k127_9273811_4 PFAM Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 306.0
HKD2_k127_9273811_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 287.0
HKD2_k127_9273811_6 PFAM GPR1 FUN34 yaaH family protein K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001869 271.0
HKD2_k127_9273811_7 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000001563 230.0
HKD2_k127_9273811_8 Fumarylacetoacetase N-terminal - - - 0.0000000000000000000000000000000000000000000000008688 176.0
HKD2_k127_9273811_9 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000001377 172.0
HKD2_k127_9281920_0 Alkyl sulfatase dimerisation K01138 - - 0.0 1179.0
HKD2_k127_9281920_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000005376 213.0
HKD2_k127_9281920_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000232 168.0
HKD2_k127_9281920_3 - - - - 0.000003188 52.0
HKD2_k127_9322671_0 Anthranilate synthase component I, N terminal region K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 513.0
HKD2_k127_9322671_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 306.0
HKD2_k127_9322671_2 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005847 276.0
HKD2_k127_9322671_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000254 280.0
HKD2_k127_9322671_4 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.000000000000000000000000000001915 126.0
HKD2_k127_9340652_0 Sugar (and other) transporter K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 415.0
HKD2_k127_9340652_1 Cysteine-rich motif following a subset of SET domains K07117 - - 0.00000000000000000000000000000005551 128.0
HKD2_k127_9340652_2 Multicopper oxidase - - - 0.0000000001014 71.0
HKD2_k127_9340652_3 copper resistance - - - 0.000002392 58.0
HKD2_k127_9343665_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005296 296.0
HKD2_k127_9343665_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000261 282.0
HKD2_k127_9343665_2 Adenylate cyclase - - - 0.0000000002117 69.0
HKD2_k127_9343665_3 - - - - 0.000000001319 68.0
HKD2_k127_935853_0 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 463.0
HKD2_k127_935853_1 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 416.0
HKD2_k127_935853_2 F5/8 type C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 326.0
HKD2_k127_935853_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000006201 157.0
HKD2_k127_9367566_0 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 335.0
HKD2_k127_9367566_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 309.0
HKD2_k127_9367566_2 - K06039 - - 0.00000000000000000000000000000000000000000000000000001877 191.0
HKD2_k127_9367566_3 - - - - 0.000000000000000000000000000000001181 135.0
HKD2_k127_9367566_4 Protein of unknown function (DUF2834) - - - 0.000000000000000000000000000001894 125.0
HKD2_k127_9367566_5 YjbR - - - 0.000000000000000000000000002479 113.0
HKD2_k127_9367566_6 - - - - 0.000000000000000000000000237 113.0
HKD2_k127_9367566_7 Virulence factor Mce family protein K02067 - - 0.00000000000000000005979 102.0
HKD2_k127_9367566_8 DUF167 K09131 - - 0.0000000000000001971 82.0
HKD2_k127_936853_0 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 460.0
HKD2_k127_936853_1 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 421.0
HKD2_k127_936853_2 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 402.0
HKD2_k127_936853_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 382.0
HKD2_k127_936853_4 FRG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002381 261.0
HKD2_k127_936853_5 - - - - 0.00000000000000000000000000000000001912 143.0
HKD2_k127_936853_6 Adenylate cyclase - - - 0.0000000000000000000005121 100.0
HKD2_k127_936853_7 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.000000000000000005796 89.0
HKD2_k127_936853_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000007055 76.0
HKD2_k127_936853_9 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000000748 62.0
HKD2_k127_9386309_0 AAA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 285.0
HKD2_k127_9386309_1 - - - - 0.000000000000000000000000000000000000000000000000000248 194.0
HKD2_k127_9386309_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000000387 123.0
HKD2_k127_9386309_3 mRNA binding - - - 0.000000000000000000002222 99.0
HKD2_k127_9500000_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 563.0
HKD2_k127_9500000_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 515.0
HKD2_k127_9500000_2 PFAM Three-deoxy-D-manno-octulosonic-acid transferase domain protein K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 381.0
HKD2_k127_9500000_3 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 305.0
HKD2_k127_9500000_4 Diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 299.0
HKD2_k127_9500000_5 Protein involved in outer membrane biogenesis K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000002324 249.0
HKD2_k127_9500000_6 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000001799 165.0
HKD2_k127_9500000_7 Sphingolipid Delta4-desaturase (DES) K04712 - 1.14.18.5,1.14.19.17 0.000000005384 58.0
HKD2_k127_9500000_8 - - - - 0.00006125 48.0
HKD2_k127_9502800_0 COG4117 Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008906 531.0
HKD2_k127_9502800_1 aminotransferase class I and II K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 357.0
HKD2_k127_9502800_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001249 284.0
HKD2_k127_9502800_3 Domain of unknown function (DUF5069) - - - 0.00000000000000000000000000000000000000000000000000001433 192.0
HKD2_k127_9502800_4 - - - - 0.000000000000000000001221 97.0
HKD2_k127_9507738_0 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000005586 236.0
HKD2_k127_9507738_1 DNA integration K07497 - - 0.0000000000000000000000000000000000000009314 162.0
HKD2_k127_9507738_2 Short repeat of unknown function (DUF308) - - - 0.00001508 51.0
HKD2_k127_9659818_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 574.0
HKD2_k127_9659818_1 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 454.0
HKD2_k127_9659818_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000005003 124.0
HKD2_k127_9659818_3 - - - - 0.000000000005452 77.0
HKD2_k127_9661570_0 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 391.0
HKD2_k127_9661570_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 295.0
HKD2_k127_9661570_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008844 237.0
HKD2_k127_9661570_3 NLP P60 protein - - - 0.0000000000000000000000000000000000000000000000004817 180.0
HKD2_k127_9661570_4 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000001122 150.0
HKD2_k127_9661570_5 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000001671 92.0
HKD2_k127_9661570_6 Endonuclease containing a URI domain K07461 - - 0.00000000000000000224 87.0
HKD2_k127_9661570_7 Belongs to the 'phage' integrase family - - - 0.00000000000000001249 85.0
HKD2_k127_9703084_0 4Fe-4S dicluster domain K00184 - - 0.0 1112.0
HKD2_k127_9703084_1 PFAM Polysulphide reductase NrfD K00185 - - 1.294e-215 678.0
HKD2_k127_9703084_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
HKD2_k127_9703084_11 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000001865 228.0
HKD2_k127_9703084_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000007053 177.0
HKD2_k127_9703084_13 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000003081 170.0
HKD2_k127_9703084_14 Chaperone of endosialidase - - - 0.0000000000000000001772 101.0
HKD2_k127_9703084_15 Hep Hag repeat protein K07278,K21449 - - 0.0000000000005257 81.0
HKD2_k127_9703084_2 COGs COG3278 Cbb3-type cytochrome oxidase subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 482.0
HKD2_k127_9703084_3 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 417.0
HKD2_k127_9703084_4 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 360.0
HKD2_k127_9703084_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 365.0
HKD2_k127_9703084_6 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 339.0
HKD2_k127_9703084_7 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 295.0
HKD2_k127_9703084_8 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005562 257.0
HKD2_k127_9703084_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009978 264.0
HKD2_k127_9757880_0 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000003025 228.0
HKD2_k127_9757880_1 PFAM Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000111 225.0
HKD2_k127_9757880_2 Type I 3-dehydroquinase K03785 - 4.2.1.10 0.00000000000000000000000000000000000001029 153.0
HKD2_k127_9757880_3 PFAM peptidase S16 lon domain protein K01338 - 3.4.21.53 0.00000000002181 68.0
HKD2_k127_9757880_4 glycosyl transferase family 39 K00721 - 2.4.1.83 0.0000000002083 73.0
HKD2_k127_9757880_5 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000003064 60.0