logo

Overview

ID MAG01793
Name HKD2_bin.35
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfobacteria
Order Desulfobacterales
Family UBA2174_A
Genus SpSt-501
Species
Assembly information
Completeness (%) 90.4
Contamination (%) 1.38
GC content (%) 68.0
N50 (bp) 13,294
Genome size (bp) 3,204,907

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2922

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10014266_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 5.485e-213 668.0
HKD2_k127_10014266_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 611.0
HKD2_k127_10014266_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 307.0
HKD2_k127_10014266_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
HKD2_k127_10014266_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000001465 216.0
HKD2_k127_10014266_5 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000002221 181.0
HKD2_k127_10014266_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000002444 186.0
HKD2_k127_10014266_7 - - - - 0.00000006927 63.0
HKD2_k127_10066912_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 519.0
HKD2_k127_10066912_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 386.0
HKD2_k127_10066912_2 Glycine cleavage system H protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000007039 205.0
HKD2_k127_10066912_3 nitrate reductase activity - - - 0.000000000000000000000000000000000000001462 153.0
HKD2_k127_10066912_4 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000000000000000000001547 151.0
HKD2_k127_10138259_0 4Fe-4S dicluster domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.853e-259 816.0
HKD2_k127_10138259_1 PFAM ATP-binding region ATPase domain protein K02482,K10819 - 2.7.13.3 1.123e-222 708.0
HKD2_k127_10138259_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000000000000985 192.0
HKD2_k127_10138259_11 - - - - 0.00000000000000000000000000000000000000000001598 175.0
HKD2_k127_10138259_12 - - - - 0.00000000000000000000000000000000001744 140.0
HKD2_k127_10138259_13 cheY-homologous receiver domain - - - 0.00000000000000000000000000009271 129.0
HKD2_k127_10138259_14 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000005377 110.0
HKD2_k127_10138259_15 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000004853 98.0
HKD2_k127_10138259_16 Regulatory protein, FmdB - - - 0.00000000000000001446 83.0
HKD2_k127_10138259_17 Sporulation related domain - - - 0.0000000000007852 81.0
HKD2_k127_10138259_2 Transglycosylase - - - 9.399e-220 719.0
HKD2_k127_10138259_3 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.826e-194 610.0
HKD2_k127_10138259_4 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 506.0
HKD2_k127_10138259_5 Class III cytochrome C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 501.0
HKD2_k127_10138259_6 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 458.0
HKD2_k127_10138259_7 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 370.0
HKD2_k127_10138259_8 nitrate reductase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
HKD2_k127_10138259_9 - - - - 0.000000000000000000000000000000000000000000000000000006505 194.0
HKD2_k127_10158298_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.43e-214 697.0
HKD2_k127_10158298_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 576.0
HKD2_k127_10158298_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 565.0
HKD2_k127_10158298_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 489.0
HKD2_k127_10158298_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 368.0
HKD2_k127_10158298_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000001027 213.0
HKD2_k127_10158298_6 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000000000000002552 189.0
HKD2_k127_10158298_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000003295 169.0
HKD2_k127_10158298_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775,K20707 - 5.1.1.1,5.1.1.5 0.00000000000004047 73.0
HKD2_k127_10158298_9 Branched-chain amino acid transport system / permease component K01998 - - 0.0007647 44.0
HKD2_k127_10169179_0 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K14447 - 5.4.99.63 1.707e-266 840.0
HKD2_k127_10169179_1 acyl-CoA transferases carnitine dehydratase K08298 GO:0003674,GO:0003824,GO:0006575,GO:0006577,GO:0006579,GO:0006807,GO:0008150,GO:0008152,GO:0008735,GO:0009056,GO:0009437,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0034641,GO:0042219,GO:0042413,GO:0044237,GO:0044248,GO:0044270,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 2.8.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 491.0
HKD2_k127_10169179_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001861 248.0
HKD2_k127_10169179_11 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000005945 243.0
HKD2_k127_10169179_12 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000177 164.0
HKD2_k127_10169179_13 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000006958 154.0
HKD2_k127_10169179_14 regulatory protein GntR HTH - - - 0.00000000000000000000000000319 120.0
HKD2_k127_10169179_15 Transcriptional regulator, GntR family - - - 0.000000000000000000000000004005 124.0
HKD2_k127_10169179_16 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000003516 72.0
HKD2_k127_10169179_17 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000023 55.0
HKD2_k127_10169179_18 succinate dehydrogenase K00241 - - 0.00006464 55.0
HKD2_k127_10169179_2 sarcosine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 444.0
HKD2_k127_10169179_3 succinate dehydrogenase K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 434.0
HKD2_k127_10169179_4 protein involved in propionate catabolism K01720 - 4.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 374.0
HKD2_k127_10169179_5 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 350.0
HKD2_k127_10169179_6 L-phenylalanine transmembrane transporter activity K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 327.0
HKD2_k127_10169179_7 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
HKD2_k127_10169179_8 leucine import across plasma membrane K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 307.0
HKD2_k127_10169179_9 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 263.0
HKD2_k127_10183501_0 ABC transporter K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 409.0
HKD2_k127_10183501_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 385.0
HKD2_k127_10183501_2 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 389.0
HKD2_k127_10183501_3 Binding-protein-dependent transport system inner membrane component K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 372.0
HKD2_k127_10183501_4 PFAM ABC transporter related K02049,K15555 - - 0.000000000000000000000000000000000000000000001458 168.0
HKD2_k127_10183501_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000008204 147.0
HKD2_k127_10183501_6 Smr domain - - - 0.000000000000000000000000971 108.0
HKD2_k127_10183501_7 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00003922 47.0
HKD2_k127_1050528_0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K01586 - 4.1.1.20 1.668e-197 627.0
HKD2_k127_1050528_1 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007171 572.0
HKD2_k127_1050528_2 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 330.0
HKD2_k127_1050528_3 PFAM asparagine synthase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
HKD2_k127_1050528_4 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000003335 124.0
HKD2_k127_1050528_5 Major Facilitator Superfamily - - - 0.0000000000000000000000004644 111.0
HKD2_k127_106065_0 PFAM Acetyl-CoA hydrolase transferase - - - 1.19e-258 811.0
HKD2_k127_106065_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 3.585e-201 631.0
HKD2_k127_106065_10 Belongs to the peptidase S11 family K01286,K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002202 258.0
HKD2_k127_106065_11 PFAM Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000006163 229.0
HKD2_k127_106065_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000001117 218.0
HKD2_k127_106065_13 phosphorelay signal transduction system - - - 0.00000000000000007817 95.0
HKD2_k127_106065_14 transmembrane signaling receptor activity K00575,K03406,K13924 - 2.1.1.80,3.1.1.61 0.00000000003637 63.0
HKD2_k127_106065_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 606.0
HKD2_k127_106065_3 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 595.0
HKD2_k127_106065_4 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 436.0
HKD2_k127_106065_5 esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 353.0
HKD2_k127_106065_6 PFAM chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 369.0
HKD2_k127_106065_7 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 366.0
HKD2_k127_106065_8 Cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 332.0
HKD2_k127_106065_9 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001236 274.0
HKD2_k127_1156496_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 588.0
HKD2_k127_1156496_1 Efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 496.0
HKD2_k127_1156496_10 PFAM CoA-binding domain protein K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000009214 119.0
HKD2_k127_1156496_11 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000001235 123.0
HKD2_k127_1156496_12 Regulatory protein MarR - - - 0.00000000000000000000002538 106.0
HKD2_k127_1156496_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 478.0
HKD2_k127_1156496_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 321.0
HKD2_k127_1156496_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 328.0
HKD2_k127_1156496_5 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003359 275.0
HKD2_k127_1156496_6 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000003392 194.0
HKD2_k127_1156496_7 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000000004426 179.0
HKD2_k127_1156496_8 MlaC protein K07323 - - 0.0000000000000000000000000000000000002585 144.0
HKD2_k127_1156496_9 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000002756 148.0
HKD2_k127_1283134_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1060.0
HKD2_k127_1283134_1 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 601.0
HKD2_k127_1283134_2 PFAM type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 600.0
HKD2_k127_1283134_3 PFAM DNA topoisomerase type IA zn finger domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 301.0
HKD2_k127_1283134_4 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000000000002093 219.0
HKD2_k127_1283134_5 DivIVA protein K04074 - - 0.00000000000000000000000000000000001536 148.0
HKD2_k127_1283134_6 YGGT family K02221 - - 0.000000000000000000000000000000002336 134.0
HKD2_k127_1286983_0 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 387.0
HKD2_k127_1286983_1 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 303.0
HKD2_k127_1286983_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000004542 138.0
HKD2_k127_1286983_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000006387 100.0
HKD2_k127_1286983_4 Transcriptional regulator - - - 0.00000000000001457 76.0
HKD2_k127_130234_0 Phosphoglucose isomerase K01810 - 5.3.1.9 4.353e-233 736.0
HKD2_k127_130234_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 538.0
HKD2_k127_130234_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000002564 130.0
HKD2_k127_130234_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000007774 123.0
HKD2_k127_130234_12 - - - - 0.00000000000000000000000009511 115.0
HKD2_k127_130234_2 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 384.0
HKD2_k127_130234_3 ABC transporter substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 354.0
HKD2_k127_130234_4 Histidine ammonia-lyase K01745,K10774 GO:0003674,GO:0003824,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016866,GO:0016869,GO:0050368 4.3.1.23,4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006261 353.0
HKD2_k127_130234_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 324.0
HKD2_k127_130234_6 Glyoxalase-like domain K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001214 280.0
HKD2_k127_130234_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000009177 269.0
HKD2_k127_130234_8 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000001134 182.0
HKD2_k127_130234_9 PilZ domain - - - 0.0000000000000000000000000000003809 128.0
HKD2_k127_133440_0 PFAM ferredoxin - - - 9.216e-284 887.0
HKD2_k127_133440_1 PFAM Acetyl-CoA hydrolase transferase - - - 8.911e-280 872.0
HKD2_k127_133440_10 PspC domain protein K03973 - - 0.0000000000000000000000000000000000009554 142.0
HKD2_k127_133440_11 - - - - 0.00000008262 57.0
HKD2_k127_133440_12 - - - - 0.0001541 48.0
HKD2_k127_133440_13 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0001665 45.0
HKD2_k127_133440_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 578.0
HKD2_k127_133440_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 491.0
HKD2_k127_133440_4 DNA recombination protein RmuC K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 446.0
HKD2_k127_133440_5 Sigma-54 interaction domain K03974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 415.0
HKD2_k127_133440_6 Exonuclease C-terminal K01141 - 3.1.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 392.0
HKD2_k127_133440_7 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002556 245.0
HKD2_k127_133440_8 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.00000000000000000000000000000000000000000000000000000000000000008043 239.0
HKD2_k127_133440_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
HKD2_k127_1355790_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 5.407e-269 836.0
HKD2_k127_1355790_1 Biotin carboxylase C-terminal domain K01965,K01968 - 6.4.1.3,6.4.1.4 2.585e-226 716.0
HKD2_k127_1355790_2 DNA-directed DNA polymerase activity K02347,K04477 - - 1.957e-213 678.0
HKD2_k127_1355790_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.84e-197 639.0
HKD2_k127_1355790_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000002573 136.0
HKD2_k127_1355790_5 DsrE/DsrF-like family K09004 - - 0.00000000000000000000002941 117.0
HKD2_k127_1360494_0 FecR protein - - - 4.788e-304 967.0
HKD2_k127_1360494_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 603.0
HKD2_k127_1360494_10 - - - - 0.0000000000000000001545 97.0
HKD2_k127_1360494_11 PFAM Cell wall hydrolase, SleB K01449 - 3.5.1.28 0.000001984 53.0
HKD2_k127_1360494_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 527.0
HKD2_k127_1360494_3 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 514.0
HKD2_k127_1360494_4 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 391.0
HKD2_k127_1360494_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 348.0
HKD2_k127_1360494_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000002131 236.0
HKD2_k127_1360494_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000008285 155.0
HKD2_k127_1360494_8 KR domain K00059 - 1.1.1.100 0.00000000000000000000009411 98.0
HKD2_k127_1360494_9 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 - - 0.00000000000000000000016 99.0
HKD2_k127_1367764_0 ABC-type sugar transport system periplasmic component K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 370.0
HKD2_k127_1367764_1 binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
HKD2_k127_1367764_2 TOBE domain K10112 - - 0.0000000000000000000000000000000000000000000000000000000000002429 215.0
HKD2_k127_1369578_0 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 540.0
HKD2_k127_1369578_1 two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 503.0
HKD2_k127_1369578_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008723 273.0
HKD2_k127_1369578_4 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000003881 222.0
HKD2_k127_1369578_5 Coenzyme F420-reducing hydrogenase, alpha subunit K00436 - 1.12.1.2 0.0000000000000000000398 90.0
HKD2_k127_1369578_6 Initiates the rapid degradation of small, acid-soluble proteins during spore germination - - - 0.000000000006141 74.0
HKD2_k127_1374132_0 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 484.0
HKD2_k127_1374132_1 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 466.0
HKD2_k127_1374132_10 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000003518 186.0
HKD2_k127_1374132_11 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000001249 151.0
HKD2_k127_1374132_12 - - - - 0.00000000000000000000000003022 113.0
HKD2_k127_1374132_13 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000004412 79.0
HKD2_k127_1374132_2 Dicarboxylate carrier protein MatC N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 446.0
HKD2_k127_1374132_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 403.0
HKD2_k127_1374132_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 338.0
HKD2_k127_1374132_5 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 344.0
HKD2_k127_1374132_6 pfam abc K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 340.0
HKD2_k127_1374132_7 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 284.0
HKD2_k127_1374132_8 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002083 281.0
HKD2_k127_1374132_9 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006306 281.0
HKD2_k127_1395969_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 3.077e-250 796.0
HKD2_k127_1395969_1 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 383.0
HKD2_k127_1395969_2 ATPases associated with a variety of cellular activities K05816 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 327.0
HKD2_k127_1395969_3 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 329.0
HKD2_k127_1395969_4 NADP oxidoreductase coenzyme F420-dependent K00286 - 1.5.1.2 0.0000000000000000000000000000000006081 140.0
HKD2_k127_1395969_6 Outer membrane lipoprotein Slp family K07285 - - 0.000001289 51.0
HKD2_k127_1403798_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1195.0
HKD2_k127_1403798_1 PFAM ATP-binding region ATPase domain protein K10819 - 2.7.13.3 8.549e-239 758.0
HKD2_k127_1403798_10 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000000000000000000000000000000000000000005663 188.0
HKD2_k127_1403798_11 DoxX - - - 0.000000000000000000000000000000000000000000000399 172.0
HKD2_k127_1403798_12 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000004249 176.0
HKD2_k127_1403798_13 Redoxin domain protein - - - 0.000000000000000000000000000000000000000000001041 171.0
HKD2_k127_1403798_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000002474 147.0
HKD2_k127_1403798_15 - - - - 0.00000000000323 76.0
HKD2_k127_1403798_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 541.0
HKD2_k127_1403798_3 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 544.0
HKD2_k127_1403798_4 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 321.0
HKD2_k127_1403798_5 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 313.0
HKD2_k127_1403798_6 TAT (twin-arginine translocation) pathway signal sequence K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001279 271.0
HKD2_k127_1403798_7 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005556 255.0
HKD2_k127_1403798_8 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000084 264.0
HKD2_k127_1403798_9 Necessary for formate dehydrogenase activity K02380 - - 0.0000000000000000000000000000000000000000000000000000000000004956 222.0
HKD2_k127_1478039_0 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 453.0
HKD2_k127_1478039_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 353.0
HKD2_k127_1478039_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001088 269.0
HKD2_k127_1478039_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000002857 185.0
HKD2_k127_1478039_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000139 145.0
HKD2_k127_1478039_5 endonuclease containing a URI domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.0000000000000000000004913 100.0
HKD2_k127_1478039_6 - - - - 0.00000000000009832 73.0
HKD2_k127_1520716_0 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 298.0
HKD2_k127_1520716_1 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008323 282.0
HKD2_k127_1520716_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000004738 218.0
HKD2_k127_1520716_3 protein conserved in bacteria K09793 - - 0.0000000000000000000000000000000000000000000003444 172.0
HKD2_k127_1579132_0 cysteine-tRNA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 434.0
HKD2_k127_1579132_1 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 316.0
HKD2_k127_1579132_2 Glycosyl transferase group 1 K00696,K13058 GO:0003674,GO:0003824,GO:0005975,GO:0005984,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0034637,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0046351,GO:0071704,GO:1901576 2.4.1.14,2.4.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 310.0
HKD2_k127_1579132_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007517 239.0
HKD2_k127_1587470_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.528e-235 735.0
HKD2_k127_1587470_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.126e-199 632.0
HKD2_k127_1587470_10 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000001036 149.0
HKD2_k127_1587470_11 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000008885 150.0
HKD2_k127_1587470_12 - - - - 0.00000000000005019 76.0
HKD2_k127_1587470_2 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 522.0
HKD2_k127_1587470_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 509.0
HKD2_k127_1587470_4 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 477.0
HKD2_k127_1587470_5 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 459.0
HKD2_k127_1587470_6 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 461.0
HKD2_k127_1587470_7 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 327.0
HKD2_k127_1587470_8 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001705 252.0
HKD2_k127_1587470_9 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000000000000000000000000000000000000001351 197.0
HKD2_k127_1601811_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1089.0
HKD2_k127_1601811_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 412.0
HKD2_k127_1601811_2 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 349.0
HKD2_k127_1601811_3 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000002735 172.0
HKD2_k127_1601811_4 CRS1_YhbY K07574 - - 0.000000000000000000000000000008725 121.0
HKD2_k127_1601811_5 - - - - 0.00000000000000000000000000001363 119.0
HKD2_k127_1601811_6 - K01507 - 3.6.1.1 0.00000000000000000000000000002589 120.0
HKD2_k127_1601811_7 Uncharacterized protein family UPF0016 - - - 0.000000000000000000001891 99.0
HKD2_k127_1606639_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 610.0
HKD2_k127_1606639_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 408.0
HKD2_k127_1606639_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002183 276.0
HKD2_k127_1606639_3 membrane K07794 - - 0.00000001309 63.0
HKD2_k127_1617095_0 pyruvate phosphate dikinase - - - 1.202e-229 747.0
HKD2_k127_1617095_1 Short chain fatty acid transporter K02106 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 507.0
HKD2_k127_1617095_2 - - - - 0.0000002806 58.0
HKD2_k127_1617095_4 - - - - 0.0009281 50.0
HKD2_k127_1621744_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 600.0
HKD2_k127_1621744_1 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 539.0
HKD2_k127_1621744_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008397 524.0
HKD2_k127_1621744_3 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 478.0
HKD2_k127_1621744_4 Dimethylamine methyltransferase (Dimeth_PyL) K16178 - 2.1.1.249 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 427.0
HKD2_k127_1621744_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 362.0
HKD2_k127_1621744_6 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 290.0
HKD2_k127_1621744_7 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002981 260.0
HKD2_k127_1621744_8 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000002907 164.0
HKD2_k127_1621744_9 Dimethylamine methyltransferase (Dimeth_PyL) K16178 - 2.1.1.249 0.0000000000000000000000000000000006347 133.0
HKD2_k127_1643808_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 330.0
HKD2_k127_1643808_1 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002599 289.0
HKD2_k127_1643808_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000002667 218.0
HKD2_k127_1643808_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000002611 164.0
HKD2_k127_1643808_5 Prokaryotic N-terminal methylation motif - - - 0.0000000000000003361 83.0
HKD2_k127_1643808_6 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000007875 79.0
HKD2_k127_1679164_0 Proton-conducting membrane transporter K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 578.0
HKD2_k127_1679164_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 580.0
HKD2_k127_1679164_10 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.00000000000000003206 83.0
HKD2_k127_1679164_2 plastoquinone (Complex I) K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 516.0
HKD2_k127_1679164_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 334.0
HKD2_k127_1679164_4 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 303.0
HKD2_k127_1679164_5 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000003311 231.0
HKD2_k127_1679164_6 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.00000000000000000000000000000000000000000000000000000000000008868 218.0
HKD2_k127_1679164_7 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000003586 194.0
HKD2_k127_1679164_8 Zinc-binding dehydrogenase K00008,K00060 - 1.1.1.103,1.1.1.14 0.00000000000000000000000000000000000004813 147.0
HKD2_k127_1682862_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 382.0
HKD2_k127_1682862_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 325.0
HKD2_k127_1682862_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 293.0
HKD2_k127_1682862_3 PFAM import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000006795 232.0
HKD2_k127_1682862_4 PFAM Xylose - - - 0.0000000000000000000000000000000000000000000000000001766 194.0
HKD2_k127_1707266_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 466.0
HKD2_k127_1707266_1 leucine import across plasma membrane K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 327.0
HKD2_k127_1707266_2 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001655 282.0
HKD2_k127_1707266_3 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000286 257.0
HKD2_k127_1707266_4 L-phenylalanine transmembrane transporter activity K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006071 259.0
HKD2_k127_1710328_0 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 595.0
HKD2_k127_1710328_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 366.0
HKD2_k127_1710328_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 298.0
HKD2_k127_1710328_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009681 267.0
HKD2_k127_1710328_4 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002821 250.0
HKD2_k127_1710328_5 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003512 243.0
HKD2_k127_1710328_6 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000002566 188.0
HKD2_k127_1710328_7 Diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000000000000000191 157.0
HKD2_k127_1710328_8 - - - - 0.0001343 50.0
HKD2_k127_179153_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.94e-261 814.0
HKD2_k127_179153_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001326 256.0
HKD2_k127_179153_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004925 250.0
HKD2_k127_179153_3 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000001719 183.0
HKD2_k127_179153_4 helix_turn_helix gluconate operon transcriptional repressor K05799 - - 0.0000000000000000000000000000000000000000000004493 175.0
HKD2_k127_179153_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000002036 146.0
HKD2_k127_179153_6 Cysteine-rich motif following a subset of SET domains K07117 - - 0.000000000000000000000000002645 126.0
HKD2_k127_179153_7 Domain of unknown function (DUF296) K06934 - - 0.00003227 56.0
HKD2_k127_1834253_0 PFAM ABC-type transporter, integral membrane subunit K05778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 591.0
HKD2_k127_1834253_1 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 515.0
HKD2_k127_1834253_10 PFAM DNA polymerase, beta domain protein region - - - 0.0000000003141 66.0
HKD2_k127_1834253_11 - - - - 0.0000004941 63.0
HKD2_k127_1834253_2 Bacterial extracellular solute-binding protein K02055,K05777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 494.0
HKD2_k127_1834253_3 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 470.0
HKD2_k127_1834253_4 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 400.0
HKD2_k127_1834253_5 succinylglutamate desuccinylase aspartoacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 379.0
HKD2_k127_1834253_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001254 291.0
HKD2_k127_1834253_7 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002967 263.0
HKD2_k127_1834253_8 - - - - 0.00000000000000000000000000000002154 138.0
HKD2_k127_1834253_9 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000002864 115.0
HKD2_k127_1835215_0 PFAM Sulfatase - - - 9.216e-312 958.0
HKD2_k127_1835215_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 566.0
HKD2_k127_1835215_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 419.0
HKD2_k127_1835215_3 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 407.0
HKD2_k127_1835215_4 Amidohydrolase family K01305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 347.0
HKD2_k127_1835215_5 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000001648 237.0
HKD2_k127_1835215_6 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000003018 227.0
HKD2_k127_1835215_8 FCD - - - 0.00000000000000000003673 103.0
HKD2_k127_1835215_9 membrane K07794 - - 0.00000000000000003141 89.0
HKD2_k127_1860635_0 TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1077.0
HKD2_k127_1860635_1 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 1.262e-265 843.0
HKD2_k127_1860635_10 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 450.0
HKD2_k127_1860635_11 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 439.0
HKD2_k127_1860635_12 TIGRFAM cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 454.0
HKD2_k127_1860635_13 protein conserved in bacteria K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 436.0
HKD2_k127_1860635_14 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 402.0
HKD2_k127_1860635_15 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 395.0
HKD2_k127_1860635_16 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 357.0
HKD2_k127_1860635_17 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 356.0
HKD2_k127_1860635_18 epimerase dehydratase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 292.0
HKD2_k127_1860635_19 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003713 281.0
HKD2_k127_1860635_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 3.188e-223 699.0
HKD2_k127_1860635_20 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001998 271.0
HKD2_k127_1860635_21 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001554 254.0
HKD2_k127_1860635_22 Domain of unknown function (DUF4881) - - - 0.00000000000000000000000000000000000000000000000000000000000000002086 244.0
HKD2_k127_1860635_23 - - - - 0.000000000000000000000000000000000000000000000000000000000003292 217.0
HKD2_k127_1860635_24 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.0000000000000000000000000000000000000000000000000000000001744 217.0
HKD2_k127_1860635_25 - - - - 0.0000000000000000000000000000000000000000000000000000000003397 203.0
HKD2_k127_1860635_26 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000001925 190.0
HKD2_k127_1860635_27 - - - - 0.00000000000000000000000000000000000000000000003599 176.0
HKD2_k127_1860635_28 PFAM Fimbrial assembly K02663 - - 0.000000000000000000000000000000000000000000002979 173.0
HKD2_k127_1860635_29 SH3 domain - - - 0.00000000000000000000000000000000000000000001043 167.0
HKD2_k127_1860635_3 PFAM sigma-54 factor interaction domain-containing protein - - - 2.201e-211 679.0
HKD2_k127_1860635_30 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000004951 167.0
HKD2_k127_1860635_31 - - - - 0.0000000000000000000000000000000000000009973 150.0
HKD2_k127_1860635_32 PFAM Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000001711 163.0
HKD2_k127_1860635_33 PFAM Glutaredoxin K06191 - - 0.00000000000000000000000000000000000000545 147.0
HKD2_k127_1860635_34 Putative inner membrane exporter, YdcZ K09936 - - 0.00000000000000000000000000000000000008396 147.0
HKD2_k127_1860635_35 HD domain - - - 0.0000000000000000000000000000000000007324 149.0
HKD2_k127_1860635_36 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000001118 135.0
HKD2_k127_1860635_37 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000002387 126.0
HKD2_k127_1860635_38 regulatory protein, FmdB family - - - 0.0000000000000000000002003 99.0
HKD2_k127_1860635_39 Helix-turn-helix - - - 0.0000000000000000005972 88.0
HKD2_k127_1860635_4 response regulator receiver K02481 - - 4.819e-206 649.0
HKD2_k127_1860635_40 Protein of unknown function (DUF3568) - - - 0.000000000000002293 81.0
HKD2_k127_1860635_41 - - - - 0.0000000000001615 77.0
HKD2_k127_1860635_42 - - - - 0.00000008366 57.0
HKD2_k127_1860635_43 - - - - 0.0000001244 57.0
HKD2_k127_1860635_44 - - - - 0.00005243 51.0
HKD2_k127_1860635_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 605.0
HKD2_k127_1860635_6 PFAM Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 606.0
HKD2_k127_1860635_7 type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 585.0
HKD2_k127_1860635_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 554.0
HKD2_k127_1860635_9 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 511.0
HKD2_k127_1940569_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 1.626e-247 783.0
HKD2_k127_1940569_1 PFAM Polysulphide reductase, NrfD K00185 - - 2.462e-209 657.0
HKD2_k127_1940569_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 463.0
HKD2_k127_1940569_3 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 426.0
HKD2_k127_1940569_4 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 310.0
HKD2_k127_1940569_5 - - - - 0.000000000000000001286 86.0
HKD2_k127_1940569_6 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.000000001158 59.0
HKD2_k127_1950539_0 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 523.0
HKD2_k127_1950539_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 383.0
HKD2_k127_1950539_2 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 300.0
HKD2_k127_1950539_3 PFAM Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 290.0
HKD2_k127_1950539_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000005213 74.0
HKD2_k127_1950539_5 Domain of unknown function (DUF4143) - - - 0.0000000255 57.0
HKD2_k127_1950539_6 Domain of unknown function (DUF4143) K07133 - - 0.0006473 47.0
HKD2_k127_1953001_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1121.0
HKD2_k127_1953001_1 Thymidylate synthase K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 481.0
HKD2_k127_1953001_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000003444 105.0
HKD2_k127_1953001_11 Histidine kinase - - - 0.0000000000002347 83.0
HKD2_k127_1953001_13 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.0000395 46.0
HKD2_k127_1953001_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 434.0
HKD2_k127_1953001_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 401.0
HKD2_k127_1953001_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005773 286.0
HKD2_k127_1953001_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003443 263.0
HKD2_k127_1953001_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000002522 228.0
HKD2_k127_1953001_7 Pseudouridine synthase K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000005077 221.0
HKD2_k127_1953001_8 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000008842 196.0
HKD2_k127_1953001_9 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000004259 149.0
HKD2_k127_1956515_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1126.0
HKD2_k127_1956515_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.207e-223 697.0
HKD2_k127_1956515_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 469.0
HKD2_k127_1956515_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 342.0
HKD2_k127_1956515_4 - - - - 0.00000000000000000000000000000000000000003944 156.0
HKD2_k127_1956515_5 Class ii aldolase K01628,K18847 - 2.2.1.8,4.1.2.17 0.00000000001049 68.0
HKD2_k127_1956515_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000001426 51.0
HKD2_k127_1956515_7 Pkd domain containing protein K12567 - 2.7.11.1 0.000002584 54.0
HKD2_k127_1956515_8 - - - - 0.00001405 48.0
HKD2_k127_1956515_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0004252 49.0
HKD2_k127_1962751_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.455e-267 839.0
HKD2_k127_1962751_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.149e-230 722.0
HKD2_k127_1962751_2 Belongs to the UPF0597 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 565.0
HKD2_k127_1962751_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000001461 64.0
HKD2_k127_2026997_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 2.534e-200 634.0
HKD2_k127_2026997_1 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 600.0
HKD2_k127_2026997_10 - - - - 0.0000000000000000000000000000003169 124.0
HKD2_k127_2026997_11 - - - - 0.0000004134 59.0
HKD2_k127_2026997_2 Alanine-glyoxylate amino-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 546.0
HKD2_k127_2026997_3 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 509.0
HKD2_k127_2026997_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 466.0
HKD2_k127_2026997_5 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 395.0
HKD2_k127_2026997_6 Periplasmic binding protein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 409.0
HKD2_k127_2026997_7 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 302.0
HKD2_k127_2026997_8 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000657 279.0
HKD2_k127_2026997_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000004351 195.0
HKD2_k127_204146_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 6.793e-282 884.0
HKD2_k127_204146_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K00533,K05922,K06281 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6 2.437e-237 741.0
HKD2_k127_204146_2 Hydrogenase (NiFe) small subunit HydA K00534,K05927,K06282,K18008 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 496.0
HKD2_k127_204146_3 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 467.0
HKD2_k127_204146_4 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 415.0
HKD2_k127_204146_5 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000000000000009884 204.0
HKD2_k127_204146_6 - - - - 0.0000000000000000000000000000001958 130.0
HKD2_k127_204146_7 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.0000000000000000000000000008381 113.0
HKD2_k127_204146_8 HupF/HypC family K04653 - - 0.000000000000000000001732 97.0
HKD2_k127_2054853_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 562.0
HKD2_k127_2082763_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.483e-270 856.0
HKD2_k127_2082763_1 Participates in both transcription termination and antitermination K02600 - - 3.098e-195 615.0
HKD2_k127_2082763_10 Regulatory protein - - - 0.00000000000000000000000000008287 119.0
HKD2_k127_2082763_11 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000006304 89.0
HKD2_k127_2082763_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 513.0
HKD2_k127_2082763_3 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 488.0
HKD2_k127_2082763_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000028 228.0
HKD2_k127_2082763_5 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000000000000000000000000000000000000000000000000009389 218.0
HKD2_k127_2082763_6 PFAM CMP dCMP deaminase zinc-binding K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000005742 189.0
HKD2_k127_2082763_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000001714 175.0
HKD2_k127_2082763_8 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000001198 188.0
HKD2_k127_2082763_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000004763 158.0
HKD2_k127_2150770_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 3.928e-224 716.0
HKD2_k127_2150770_1 Aminomethyltransferase folate-binding domain - - - 0.000000000000000000000000000000000000000000000003327 180.0
HKD2_k127_2150770_2 PFAM binding-protein-dependent transport systems inner membrane component K05846 - - 0.00000000004904 66.0
HKD2_k127_2174179_0 Bacterial extracellular solute-binding proteins, family 5 Middle K13889 - - 2.546e-256 803.0
HKD2_k127_2174179_1 Binding-protein-dependent transport system inner membrane component K02033,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 500.0
HKD2_k127_2174179_2 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 493.0
HKD2_k127_2174179_3 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 446.0
HKD2_k127_2174179_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000176 69.0
HKD2_k127_2174179_5 Cupin domain - - - 0.0004025 52.0
HKD2_k127_2205940_0 Glycine radical K00656,K07540 - 2.3.1.54,4.1.99.11 0.0 1261.0
HKD2_k127_2205940_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 2.218e-299 930.0
HKD2_k127_2205940_10 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 573.0
HKD2_k127_2205940_11 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 551.0
HKD2_k127_2205940_12 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 498.0
HKD2_k127_2205940_13 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 342.0
HKD2_k127_2205940_14 COG1454 Alcohol dehydrogenase, class IV K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 336.0
HKD2_k127_2205940_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 338.0
HKD2_k127_2205940_16 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000266 273.0
HKD2_k127_2205940_17 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005616 269.0
HKD2_k127_2205940_18 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000001819 248.0
HKD2_k127_2205940_19 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000783 247.0
HKD2_k127_2205940_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 4.563e-284 890.0
HKD2_k127_2205940_20 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000002647 209.0
HKD2_k127_2205940_21 - - - - 0.00000000000000000000000000000000000000000000000000001526 194.0
HKD2_k127_2205940_22 - - - - 0.000000000000000000000000000000000000000000000006057 184.0
HKD2_k127_2205940_23 FCD - - - 0.0000000000000000000000001028 115.0
HKD2_k127_2205940_24 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000001781 107.0
HKD2_k127_2205940_25 K+ potassium transporter K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000002456 72.0
HKD2_k127_2205940_3 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.527e-264 829.0
HKD2_k127_2205940_4 Amino acid permease - - - 3.753e-239 753.0
HKD2_k127_2205940_5 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 7.114e-236 736.0
HKD2_k127_2205940_6 Histidine kinase K07646 - 2.7.13.3 2.979e-209 668.0
HKD2_k127_2205940_7 Sigma-54 interaction domain K11384 - - 5.599e-201 637.0
HKD2_k127_2205940_8 protein histidine kinase activity K11383 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 623.0
HKD2_k127_2205940_9 Serine dehydratase alpha chain K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 587.0
HKD2_k127_2238332_0 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 428.0
HKD2_k127_2238332_1 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 395.0
HKD2_k127_2238332_2 PFAM Vitamin B12 dependent methionine synthase, activation domain - - - 0.0000000000000000000000000000000000000000000004917 175.0
HKD2_k127_2238332_3 - - - - 0.00000000000000000000000000000000000000000003792 166.0
HKD2_k127_2268945_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.015e-218 691.0
HKD2_k127_2268945_1 acyl-CoA dehydrogenase K16173 - 1.3.99.32 1.725e-205 644.0
HKD2_k127_2268945_2 transporter, DctM subunit K11690 - - 5.893e-203 640.0
HKD2_k127_2268945_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 494.0
HKD2_k127_2268945_4 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 394.0
HKD2_k127_2268945_5 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 356.0
HKD2_k127_2268945_6 lyase activity - - - 0.0000000000000000000000000000000000000000000000003455 187.0
HKD2_k127_2268945_7 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000000000000000000000000000000003354 189.0
HKD2_k127_228174_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 6.761e-205 646.0
HKD2_k127_228174_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 463.0
HKD2_k127_228174_2 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 311.0
HKD2_k127_228174_3 DUF218 domain - - - 0.00000000000008969 81.0
HKD2_k127_2430190_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 520.0
HKD2_k127_2430190_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 464.0
HKD2_k127_2430190_10 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000002817 226.0
HKD2_k127_2430190_11 PFAM Beta-ketoacyl synthase K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000006211 186.0
HKD2_k127_2430190_12 - - - - 0.0000000000000000000000000000000001527 139.0
HKD2_k127_2430190_13 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000004981 141.0
HKD2_k127_2430190_14 - - - - 0.00000000000000000000000000006312 119.0
HKD2_k127_2430190_15 SCP-2 sterol transfer family - - - 0.0000000000000000000006862 108.0
HKD2_k127_2430190_16 Phosphopantetheine attachment site K02078 - - 0.000000000000000001805 98.0
HKD2_k127_2430190_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 430.0
HKD2_k127_2430190_3 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005712 428.0
HKD2_k127_2430190_4 Butirosin biosynthesis protein H, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 377.0
HKD2_k127_2430190_5 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 371.0
HKD2_k127_2430190_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 301.0
HKD2_k127_2430190_7 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 292.0
HKD2_k127_2430190_8 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002907 284.0
HKD2_k127_2430190_9 FR47-like protein K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000006668 226.0
HKD2_k127_2434393_0 TRAP transporter, 4TM 12TM fusion protein - - - 4.652e-216 683.0
HKD2_k127_2434393_1 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 442.0
HKD2_k127_2434393_2 Domain of unknown function (DUF1850) - - - 0.00000000000000000000000000000000000000000000000000005842 193.0
HKD2_k127_2434393_3 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000006263 72.0
HKD2_k127_2434393_4 cysteine-tRNA ligase activity - - - 0.00000002157 56.0
HKD2_k127_2488385_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.794e-239 751.0
HKD2_k127_2488385_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 512.0
HKD2_k127_2488385_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000001407 158.0
HKD2_k127_2488385_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000001712 141.0
HKD2_k127_2488385_12 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000001394 97.0
HKD2_k127_2488385_13 - - - - 0.000000000000003525 77.0
HKD2_k127_2488385_14 OsmC-like protein - - - 0.000000000002243 70.0
HKD2_k127_2488385_15 - - - - 0.0000001304 63.0
HKD2_k127_2488385_2 homoserine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 497.0
HKD2_k127_2488385_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 451.0
HKD2_k127_2488385_4 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 387.0
HKD2_k127_2488385_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 391.0
HKD2_k127_2488385_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 293.0
HKD2_k127_2488385_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005816 301.0
HKD2_k127_2488385_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
HKD2_k127_2488385_9 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000004976 245.0
HKD2_k127_2557512_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2285.0
HKD2_k127_2557512_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2161.0
HKD2_k127_2557512_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000004591 93.0
HKD2_k127_2557512_11 translation elongation factor activity K02358 - - 0.000000000000000952 76.0
HKD2_k127_2557512_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000001303 82.0
HKD2_k127_2557512_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 376.0
HKD2_k127_2557512_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 308.0
HKD2_k127_2557512_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001621 231.0
HKD2_k127_2557512_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000004882 229.0
HKD2_k127_2557512_6 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000002701 229.0
HKD2_k127_2557512_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000001995 194.0
HKD2_k127_2557512_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000002666 184.0
HKD2_k127_2557512_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001507 189.0
HKD2_k127_2558948_0 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 504.0
HKD2_k127_2558948_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 489.0
HKD2_k127_2558948_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 422.0
HKD2_k127_2558948_3 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000009644 190.0
HKD2_k127_2558948_4 AsnC-type helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000007986 181.0
HKD2_k127_2558948_5 TIGRFAM secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000008486 166.0
HKD2_k127_2573716_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 610.0
HKD2_k127_2573716_1 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 500.0
HKD2_k127_2573716_10 MaoC like domain - - - 0.0000000000000000000000000000000000000000000003827 172.0
HKD2_k127_2573716_11 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000006325 164.0
HKD2_k127_2573716_12 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000779 162.0
HKD2_k127_2573716_13 COG2931 RTX toxins and related Ca2 -binding proteins K01406,K07004 - 3.4.24.40 0.0000000000000000000001527 116.0
HKD2_k127_2573716_14 - - - - 0.00000000000000001638 84.0
HKD2_k127_2573716_15 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000232 76.0
HKD2_k127_2573716_16 involved in cell shape determination - - - 0.00000002927 60.0
HKD2_k127_2573716_17 - - - - 0.00003588 48.0
HKD2_k127_2573716_2 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 504.0
HKD2_k127_2573716_3 Protein kinase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 431.0
HKD2_k127_2573716_4 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 336.0
HKD2_k127_2573716_5 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 338.0
HKD2_k127_2573716_6 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 307.0
HKD2_k127_2573716_7 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000402 293.0
HKD2_k127_2573716_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000001436 237.0
HKD2_k127_2573716_9 AMMECR1 K06990 - - 0.000000000000000000000000000000000000000000000000001143 192.0
HKD2_k127_257512_0 Uncharacterised ACR (DUF711) K09157 - - 2.914e-218 684.0
HKD2_k127_257512_1 ABC-type Fe3 transport system permease K02011 - - 2.507e-216 694.0
HKD2_k127_257512_10 CheY-like receiver, AAA-type ATPase and DNA-binding domain-containing response regulator - - - 0.0000000000000000000000000000000000000000000000000001992 199.0
HKD2_k127_257512_11 Roadblock/LC7 domain - - - 0.0000000000000000000000000000000000000000000000000245 184.0
HKD2_k127_257512_12 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000018 183.0
HKD2_k127_257512_13 Universal stress protein - - - 0.0000000000000000000000000000000000000799 145.0
HKD2_k127_257512_14 Phosphoesterase K07095 - - 0.000000000000000000000000000000000003298 143.0
HKD2_k127_257512_15 - - - - 0.0000000000000000000000000000006155 123.0
HKD2_k127_257512_17 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000001223 90.0
HKD2_k127_257512_18 - K08086 - - 0.000000000001216 80.0
HKD2_k127_257512_2 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 632.0
HKD2_k127_257512_3 type III restriction protein res subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 547.0
HKD2_k127_257512_4 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 463.0
HKD2_k127_257512_5 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 372.0
HKD2_k127_257512_6 Cache domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 373.0
HKD2_k127_257512_7 ABC transporter K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
HKD2_k127_257512_8 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 290.0
HKD2_k127_257512_9 PFAM amino acid-binding ACT domain protein K03567 - - 0.000000000000000000000000000000000000000000000000000000004996 204.0
HKD2_k127_2588642_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 428.0
HKD2_k127_2588642_1 Tripartite ATP-independent periplasmic transporter, DctM component K21393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 423.0
HKD2_k127_2588642_10 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.00000000000000000003713 97.0
HKD2_k127_2588642_2 cobalamin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 378.0
HKD2_k127_2588642_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
HKD2_k127_2588642_4 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 336.0
HKD2_k127_2588642_5 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 335.0
HKD2_k127_2588642_6 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009142 322.0
HKD2_k127_2588642_7 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 326.0
HKD2_k127_2588642_8 FCD K05799 - - 0.0000000000000000000000000000000000000000000000131 192.0
HKD2_k127_2588642_9 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.000000000000000000000000000386 115.0
HKD2_k127_2590161_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 411.0
HKD2_k127_2590161_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002553 287.0
HKD2_k127_2590161_2 helix_turn _helix lactose operon repressor K02525,K02529 - - 0.000000000000000000000000000000000000000000000000000000000000004002 231.0
HKD2_k127_2590161_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000001259 213.0
HKD2_k127_2590161_4 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.00000000000000000000000000000000000000006513 163.0
HKD2_k127_2592286_0 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 475.0
HKD2_k127_2592286_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 378.0
HKD2_k127_2592286_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 355.0
HKD2_k127_2592286_3 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000877 211.0
HKD2_k127_2592286_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000001215 184.0
HKD2_k127_2609678_0 General secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 334.0
HKD2_k127_2609678_1 Fimbrial assembly family protein K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009374 276.0
HKD2_k127_2609678_2 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000006929 204.0
HKD2_k127_2609678_3 Prokaryotic N-terminal methylation motif K02459 - - 0.00000000000000000000000000000000000000000000004338 179.0
HKD2_k127_2609678_4 Type II secretion system (T2SS), protein M K02462 - - 0.000000000000000000000000000000000001032 149.0
HKD2_k127_2609678_5 General secretion pathway protein C K02452 - - 0.000000000000000000000000000000000003421 146.0
HKD2_k127_2609678_6 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000000000000000000000000345 151.0
HKD2_k127_2609678_7 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000000000003565 94.0
HKD2_k127_2609678_8 - - - - 0.0000000000000004296 88.0
HKD2_k127_2609678_9 General secretion pathway protein F K02455,K02653 - - 0.0000000001006 62.0
HKD2_k127_2631048_0 pfam abc-1 K03688 - - 1.626e-213 680.0
HKD2_k127_2631048_1 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 611.0
HKD2_k127_2631048_2 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 445.0
HKD2_k127_2631048_3 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 364.0
HKD2_k127_2631048_4 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 285.0
HKD2_k127_2631048_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000001512 213.0
HKD2_k127_2631048_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000001006 159.0
HKD2_k127_2631048_7 L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000002372 149.0
HKD2_k127_2631048_8 granule-associated protein - - - 0.000001076 56.0
HKD2_k127_263241_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1156.0
HKD2_k127_263241_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 597.0
HKD2_k127_263241_10 Acyclic terpene utilisation family protein AtuA - - - 0.0000000000000000000000000000000258 146.0
HKD2_k127_263241_11 transcriptional regulator, RpiR family - - - 0.000000000000000000000000002257 123.0
HKD2_k127_263241_12 - - - - 0.000000000000000000000000002528 130.0
HKD2_k127_263241_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000001209 74.0
HKD2_k127_263241_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 541.0
HKD2_k127_263241_3 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 451.0
HKD2_k127_263241_4 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 415.0
HKD2_k127_263241_5 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 322.0
HKD2_k127_263241_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 310.0
HKD2_k127_263241_7 TRAP transporter, solute receptor (TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000002527 243.0
HKD2_k127_263241_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000002647 186.0
HKD2_k127_263241_9 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000001072 160.0
HKD2_k127_265713_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.89e-233 725.0
HKD2_k127_265713_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 519.0
HKD2_k127_265713_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001273 219.0
HKD2_k127_265713_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000001216 217.0
HKD2_k127_265713_12 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000002189 207.0
HKD2_k127_265713_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001956 202.0
HKD2_k127_265713_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001149 198.0
HKD2_k127_265713_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001026 197.0
HKD2_k127_265713_16 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001194 192.0
HKD2_k127_265713_17 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000889 192.0
HKD2_k127_265713_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000004763 159.0
HKD2_k127_265713_19 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000006387 159.0
HKD2_k127_265713_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 433.0
HKD2_k127_265713_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000959 150.0
HKD2_k127_265713_21 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000001147 130.0
HKD2_k127_265713_22 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000799 127.0
HKD2_k127_265713_23 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000001228 134.0
HKD2_k127_265713_24 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003866 125.0
HKD2_k127_265713_25 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001019 110.0
HKD2_k127_265713_26 Ribosomal protein L30p/L7e K02907 - - 0.000000000000000002349 93.0
HKD2_k127_265713_27 translation elongation factor activity K02358 - - 0.000000000000000952 76.0
HKD2_k127_265713_28 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000002671 77.0
HKD2_k127_265713_29 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009565 69.0
HKD2_k127_265713_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 349.0
HKD2_k127_265713_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 340.0
HKD2_k127_265713_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 299.0
HKD2_k127_265713_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 290.0
HKD2_k127_265713_7 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 262.0
HKD2_k127_265713_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000006968 252.0
HKD2_k127_265713_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004577 251.0
HKD2_k127_2690433_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 491.0
HKD2_k127_2690433_1 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 460.0
HKD2_k127_2690433_2 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 391.0
HKD2_k127_2690433_3 signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002975 258.0
HKD2_k127_2690433_4 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000001785 227.0
HKD2_k127_2690433_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000004514 230.0
HKD2_k127_2690433_6 - - - - 0.0000000000000000000000000000000000000000000000000000004217 199.0
HKD2_k127_2690433_7 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000001681 194.0
HKD2_k127_2690433_8 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000000001516 156.0
HKD2_k127_2690433_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000005578 144.0
HKD2_k127_2694077_0 PFAM DAHP synthetase I K03856,K04516 - 2.5.1.54,5.4.99.5 3.345e-236 746.0
HKD2_k127_2694077_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 421.0
HKD2_k127_2694077_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 411.0
HKD2_k127_2694077_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000005118 104.0
HKD2_k127_2697411_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 374.0
HKD2_k127_2697411_1 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 313.0
HKD2_k127_2697411_2 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 309.0
HKD2_k127_273080_0 carbohydrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 557.0
HKD2_k127_273080_1 mannitol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007765 540.0
HKD2_k127_273080_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 371.0
HKD2_k127_273080_3 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.000000000000000000000000000000000000000000004294 172.0
HKD2_k127_273080_4 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000003128 64.0
HKD2_k127_2746799_0 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 581.0
HKD2_k127_2746799_1 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 565.0
HKD2_k127_2746799_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 482.0
HKD2_k127_2759036_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 1.426e-241 758.0
HKD2_k127_2759036_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 2.718e-194 636.0
HKD2_k127_2759036_10 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000002014 191.0
HKD2_k127_2759036_11 PFAM Peptidase M20 K01436 - - 0.0000000000000000000000000000000000000000000009207 171.0
HKD2_k127_2759036_2 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 593.0
HKD2_k127_2759036_3 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 527.0
HKD2_k127_2759036_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 415.0
HKD2_k127_2759036_5 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 406.0
HKD2_k127_2759036_6 carboxylic acid catabolic process K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 376.0
HKD2_k127_2759036_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 362.0
HKD2_k127_2759036_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
HKD2_k127_2759036_9 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002236 283.0
HKD2_k127_2805135_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1585.0
HKD2_k127_2805135_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.286e-244 765.0
HKD2_k127_2805135_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 309.0
HKD2_k127_2805135_3 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000005636 206.0
HKD2_k127_2805443_0 Aldehyde dehydrogenase family K04021 - - 8.494e-223 699.0
HKD2_k127_2805443_1 RnfC Barrel sandwich hybrid domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 593.0
HKD2_k127_2805443_10 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 314.0
HKD2_k127_2805443_11 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005389 272.0
HKD2_k127_2805443_12 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004067 267.0
HKD2_k127_2805443_13 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006115 256.0
HKD2_k127_2805443_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000621 259.0
HKD2_k127_2805443_15 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000007453 245.0
HKD2_k127_2805443_16 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000004359 218.0
HKD2_k127_2805443_17 BMC - - - 0.000000000000000000000000000000000000000000000000000000001556 207.0
HKD2_k127_2805443_18 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000687 226.0
HKD2_k127_2805443_19 Ethanolamine utilisation protein EutQ - - - 0.00000000000000000000000000000000000000001261 174.0
HKD2_k127_2805443_2 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 586.0
HKD2_k127_2805443_20 BMC K04027 - - 0.0000000000000000000000000000000000000002064 153.0
HKD2_k127_2805443_21 BMC domain K04027 - - 0.0000000000000000000000000000000000000005048 153.0
HKD2_k127_2805443_22 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000226 141.0
HKD2_k127_2805443_23 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000003686 136.0
HKD2_k127_2805443_24 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.000000000000000000000000000002803 123.0
HKD2_k127_2805443_25 BMC K04025 - - 0.00000000000000000000002872 103.0
HKD2_k127_2805443_26 Beta-lactamase superfamily domain - - - 0.00000000000000000000004019 109.0
HKD2_k127_2805443_3 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 507.0
HKD2_k127_2805443_4 Psort location CytoplasmicMembrane, score 10.00 K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 513.0
HKD2_k127_2805443_5 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009472 426.0
HKD2_k127_2805443_6 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 422.0
HKD2_k127_2805443_7 Phosphate acetyl/butaryl transferase K04020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 405.0
HKD2_k127_2805443_8 Type IV pilus assembly protein PilM; K04024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 357.0
HKD2_k127_2805443_9 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 317.0
HKD2_k127_2808332_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 516.0
HKD2_k127_2808332_1 lipoprotein transporter activity K02003,K09814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 318.0
HKD2_k127_2808332_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000003546 217.0
HKD2_k127_2808332_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000003805 186.0
HKD2_k127_2808332_4 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.00001581 48.0
HKD2_k127_2847568_0 PFAM aminotransferase class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 444.0
HKD2_k127_2847568_1 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000002245 281.0
HKD2_k127_2847568_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002195 261.0
HKD2_k127_2847568_3 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.00000000004876 73.0
HKD2_k127_2856974_0 Alpha beta hydrolase - - - 8.57e-244 768.0
HKD2_k127_2856974_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 444.0
HKD2_k127_2856974_2 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 415.0
HKD2_k127_2856974_3 Protein of unknown function (DUF533) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 312.0
HKD2_k127_2856974_4 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001022 232.0
HKD2_k127_2856974_5 response to oxidative stress K04063 - - 0.0000000000000000000000000000000000000000000003152 170.0
HKD2_k127_2856974_6 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 0.00000000000000000000000694 102.0
HKD2_k127_2858269_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 521.0
HKD2_k127_2858269_1 Peptidase family M20/M25/M40 K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 408.0
HKD2_k127_2858269_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00003,K01139 - 1.1.1.3,2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 326.0
HKD2_k127_2858269_3 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000007588 201.0
HKD2_k127_2895499_0 PFAM Type II secretion system protein E K02652 - - 8.794e-220 695.0
HKD2_k127_2895499_1 PFAM type II secretion system K02653,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 400.0
HKD2_k127_2895499_2 AAA domain K02450 - - 0.000000000000000000000000000000000007598 150.0
HKD2_k127_2897342_0 GXGXG motif - - - 0.0 1075.0
HKD2_k127_2897342_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.786e-238 742.0
HKD2_k127_2897342_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005629 232.0
HKD2_k127_2951852_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.336e-261 815.0
HKD2_k127_2951852_1 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 590.0
HKD2_k127_2951852_10 lyase activity - - - 0.000000000000000000000000000000000000000000000000001411 194.0
HKD2_k127_2951852_11 Flavodoxin domain - - - 0.00000000000000000000000000000000000000000004227 168.0
HKD2_k127_2951852_12 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.000000000000000000000000000000004183 129.0
HKD2_k127_2951852_13 - - - - 0.000000000000000000000002477 106.0
HKD2_k127_2951852_14 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000002778 106.0
HKD2_k127_2951852_15 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000001088 99.0
HKD2_k127_2951852_16 Heavy-metal-associated domain - - - 0.00000000000000000001407 92.0
HKD2_k127_2951852_17 - - - - 0.000000000000000000451 92.0
HKD2_k127_2951852_18 Rubrerythrin K19824 - - 0.000000000000000002196 86.0
HKD2_k127_2951852_19 4Fe-4S single cluster domain K05337 - - 0.00000000000000003944 94.0
HKD2_k127_2951852_2 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 357.0
HKD2_k127_2951852_3 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 325.0
HKD2_k127_2951852_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 306.0
HKD2_k127_2951852_5 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 310.0
HKD2_k127_2951852_6 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
HKD2_k127_2951852_7 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003389 269.0
HKD2_k127_2951852_8 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000000001017 226.0
HKD2_k127_2951852_9 PFAM metal-dependent phosphohydrolase HD sub - - - 0.000000000000000000000000000000000000000000000000000000000006844 215.0
HKD2_k127_2963533_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00394 - 1.8.99.2 0.0 1056.0
HKD2_k127_2963533_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 468.0
HKD2_k127_2963533_10 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000000000004197 110.0
HKD2_k127_2963533_11 energy transducer activity - - - 0.0000007428 58.0
HKD2_k127_2963533_12 COG0642 Signal transduction histidine kinase - - - 0.000001418 56.0
HKD2_k127_2963533_2 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 375.0
HKD2_k127_2963533_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 371.0
HKD2_k127_2963533_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 322.0
HKD2_k127_2963533_5 COG0518 GMP synthase - Glutamine amidotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 291.0
HKD2_k127_2963533_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002909 248.0
HKD2_k127_2963533_7 4Fe-4S dicluster domain K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000007556 192.0
HKD2_k127_2963533_8 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000003847 123.0
HKD2_k127_2963533_9 Staphylococcal nuclease homologues - - - 0.0000000000000000000000000006517 120.0
HKD2_k127_2998996_0 Protein of unknown function, DUF255 K06888 - - 9.503e-260 818.0
HKD2_k127_2998996_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 568.0
HKD2_k127_2998996_11 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.0000288 53.0
HKD2_k127_2998996_2 A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 409.0
HKD2_k127_2998996_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 360.0
HKD2_k127_2998996_4 transporter solute receptor, DctP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 291.0
HKD2_k127_2998996_5 PFAM Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001963 225.0
HKD2_k127_2998996_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000004392 221.0
HKD2_k127_2998996_7 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000001274 207.0
HKD2_k127_2998996_8 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000009522 114.0
HKD2_k127_2998996_9 Belongs to the HesB IscA family - - - 0.000000000000000000002426 94.0
HKD2_k127_3047012_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00184 - - 0.0 1108.0
HKD2_k127_3047012_1 Polysulphide reductase, NrfD K00185 - - 7.713e-217 681.0
HKD2_k127_3047012_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 512.0
HKD2_k127_3047012_3 Peptidase family M1 domain K01256,K13722 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 506.0
HKD2_k127_3047012_4 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000001972 138.0
HKD2_k127_3047012_5 Thiamine-binding protein - - - 0.00000000000000000000000000000001882 129.0
HKD2_k127_3089767_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 533.0
HKD2_k127_3089767_1 inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 328.0
HKD2_k127_3089767_2 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000102 108.0
HKD2_k127_3089767_3 ThiS family K03636 - - 0.00000003413 61.0
HKD2_k127_3089901_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0 1337.0
HKD2_k127_3089901_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 9.093e-302 936.0
HKD2_k127_3089901_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.223e-279 866.0
HKD2_k127_3089901_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.613e-195 618.0
HKD2_k127_3089901_4 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 357.0
HKD2_k127_3089901_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000004248 208.0
HKD2_k127_3089901_6 Thioredoxin - - - 0.00000000000000000000000001471 113.0
HKD2_k127_3089901_7 - - - - 0.00000000000000000000000003674 113.0
HKD2_k127_3089901_8 Thioredoxin - - - 0.00000000000000000001619 99.0
HKD2_k127_3089901_9 Cache domain - - - 0.0000000000000004994 89.0
HKD2_k127_3104588_0 CBS domain K00974 - 2.7.7.72 0.0 1059.0
HKD2_k127_3104588_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.809e-263 837.0
HKD2_k127_3104588_10 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009807 266.0
HKD2_k127_3104588_11 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006175 252.0
HKD2_k127_3104588_12 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000000000000000000009104 226.0
HKD2_k127_3104588_13 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
HKD2_k127_3104588_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000194 229.0
HKD2_k127_3104588_15 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002982 218.0
HKD2_k127_3104588_16 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000001886 210.0
HKD2_k127_3104588_17 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000001438 197.0
HKD2_k127_3104588_18 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000002023 188.0
HKD2_k127_3104588_19 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000001726 145.0
HKD2_k127_3104588_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.34e-236 739.0
HKD2_k127_3104588_20 Belongs to the UPF0296 family K09777 - - 0.000000000000000000000000000000000005059 140.0
HKD2_k127_3104588_21 PFAM ATP synthase I chain - - - 0.00000000000000000000000000002192 123.0
HKD2_k127_3104588_22 PFAM Outer membrane K06142 - - 0.00000000000000000000001082 108.0
HKD2_k127_3104588_23 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000002082 98.0
HKD2_k127_3104588_24 Belongs to the UPF0434 family K09791 - - 0.00000000000000000001438 93.0
HKD2_k127_3104588_3 type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 580.0
HKD2_k127_3104588_4 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 509.0
HKD2_k127_3104588_5 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 447.0
HKD2_k127_3104588_6 PFAM ATP-binding region ATPase domain protein K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 349.0
HKD2_k127_3104588_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 297.0
HKD2_k127_3104588_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003119 275.0
HKD2_k127_3104588_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001099 275.0
HKD2_k127_3135076_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 578.0
HKD2_k127_3135076_1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 341.0
HKD2_k127_3165363_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 418.0
HKD2_k127_3165363_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 382.0
HKD2_k127_3165363_2 N-terminal TM domain of oligopeptide transport permease C K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 300.0
HKD2_k127_3226613_0 Belongs to the RtcB family K14415 - 6.5.1.3 9.735e-221 694.0
HKD2_k127_3226613_1 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 604.0
HKD2_k127_3226613_10 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002483 297.0
HKD2_k127_3226613_11 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004651 280.0
HKD2_k127_3226613_12 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000006081 239.0
HKD2_k127_3226613_13 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008854 240.0
HKD2_k127_3226613_14 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000001934 235.0
HKD2_k127_3226613_15 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000004393 194.0
HKD2_k127_3226613_16 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000000000000000000000000000005114 179.0
HKD2_k127_3226613_17 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000004942 179.0
HKD2_k127_3226613_18 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000000000008483 166.0
HKD2_k127_3226613_19 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000006367 146.0
HKD2_k127_3226613_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 536.0
HKD2_k127_3226613_20 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000002447 126.0
HKD2_k127_3226613_21 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000001456 127.0
HKD2_k127_3226613_22 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000003649 109.0
HKD2_k127_3226613_23 Bacterial SH3 domain homologues K07184 - - 0.0000000000000000000000003259 115.0
HKD2_k127_3226613_24 Cyclic nucleotide-binding domain K21563 - - 0.0000003262 52.0
HKD2_k127_3226613_3 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 495.0
HKD2_k127_3226613_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 463.0
HKD2_k127_3226613_5 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 436.0
HKD2_k127_3226613_6 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 412.0
HKD2_k127_3226613_7 PFAM nucleoside H symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 362.0
HKD2_k127_3226613_8 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 351.0
HKD2_k127_3226613_9 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 309.0
HKD2_k127_3275897_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 372.0
HKD2_k127_3275897_1 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
HKD2_k127_3275897_2 LUD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 303.0
HKD2_k127_3275897_3 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 302.0
HKD2_k127_3275897_4 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 292.0
HKD2_k127_3275897_5 - - - - 0.0000000000000000000000000000000000000000000000000008014 201.0
HKD2_k127_3275897_6 Universal stress protein - - - 0.0000000000000000000000000000000001415 136.0
HKD2_k127_3275897_7 Phospholipid-binding domain protein - - - 0.0000000000000000000000008668 115.0
HKD2_k127_3319482_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1340.0
HKD2_k127_3319482_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.2e-307 950.0
HKD2_k127_3319482_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 8.963e-208 653.0
HKD2_k127_3319482_3 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 361.0
HKD2_k127_3319482_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
HKD2_k127_3319482_5 PFAM Rhomboid family protein K07059 - - 0.000000000000000000000000000000000000000000000000000000009539 211.0
HKD2_k127_3420709_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 452.0
HKD2_k127_3420709_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 369.0
HKD2_k127_3420709_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 344.0
HKD2_k127_3420709_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008982 256.0
HKD2_k127_3429408_0 cytochrome c oxidase K00404 - 1.9.3.1 1.786e-207 656.0
HKD2_k127_3429408_1 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 7.231e-194 634.0
HKD2_k127_3429408_2 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 473.0
HKD2_k127_3429408_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000001515 156.0
HKD2_k127_3429408_4 - - - - 0.0000000000000000000000004049 106.0
HKD2_k127_3429408_5 Cytochrome oxidase maturation protein - - - 0.000000000000000007603 85.0
HKD2_k127_3429408_6 - - - - 0.0000000000000000371 83.0
HKD2_k127_3467064_0 DNA helicase K03654 - 3.6.4.12 6.157e-222 705.0
HKD2_k127_3467064_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 452.0
HKD2_k127_3467064_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000581 85.0
HKD2_k127_3467064_11 - - - - 0.0005061 44.0
HKD2_k127_3467064_2 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 436.0
HKD2_k127_3467064_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 413.0
HKD2_k127_3467064_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 366.0
HKD2_k127_3467064_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 366.0
HKD2_k127_3467064_6 mannitol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 343.0
HKD2_k127_3467064_7 transporter solute receptor, DctP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 322.0
HKD2_k127_3467064_8 Protein of unknown function (DUF2848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001189 280.0
HKD2_k127_3467064_9 3-hydroxyanthranilate 3,4-dioxygenase activity - - - 0.00000000000000000000000000001066 122.0
HKD2_k127_3476812_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 533.0
HKD2_k127_3476812_1 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 453.0
HKD2_k127_3476812_2 PFAM response regulator receiver K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 294.0
HKD2_k127_3476812_3 WYL domain K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001232 252.0
HKD2_k127_3476812_4 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000005023 160.0
HKD2_k127_3476812_5 4Fe-4S binding domain - - - 0.000002525 49.0
HKD2_k127_3503101_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1735.0
HKD2_k127_3503101_1 Pyridine nucleotide-disulphide oxidoreductase - - - 1.813e-318 987.0
HKD2_k127_3503101_10 shikimate 3-dehydrogenase (NADP+) activity K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000009383 271.0
HKD2_k127_3503101_11 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004564 233.0
HKD2_k127_3503101_12 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000001297 186.0
HKD2_k127_3503101_13 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000002876 167.0
HKD2_k127_3503101_14 DoxX - - - 0.00000000000000000000000000000000000000000009971 165.0
HKD2_k127_3503101_15 TIGRFAM C_GCAxxG_C_C family protein - - - 0.000000000000000000000000005201 123.0
HKD2_k127_3503101_16 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000001718 95.0
HKD2_k127_3503101_17 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000004218 91.0
HKD2_k127_3503101_2 Belongs to the ClpX chaperone family - - - 3.523e-217 689.0
HKD2_k127_3503101_3 PFAM Radical SAM domain protein K22226 - - 3.708e-207 660.0
HKD2_k127_3503101_4 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 564.0
HKD2_k127_3503101_5 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 508.0
HKD2_k127_3503101_6 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 493.0
HKD2_k127_3503101_7 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 479.0
HKD2_k127_3503101_8 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 355.0
HKD2_k127_3503101_9 PFAM Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 324.0
HKD2_k127_352872_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 467.0
HKD2_k127_352872_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 412.0
HKD2_k127_352872_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 397.0
HKD2_k127_352872_3 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 386.0
HKD2_k127_352872_4 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 355.0
HKD2_k127_352872_5 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 345.0
HKD2_k127_352872_6 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000004344 224.0
HKD2_k127_352872_7 PFAM Tripartite ATP-independent periplasmic - - - 0.00000000000131 75.0
HKD2_k127_352872_8 Xylose isomerase-like TIM barrel - - - 0.000000000002578 77.0
HKD2_k127_3600614_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1061.0
HKD2_k127_3600614_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 423.0
HKD2_k127_3600614_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000001237 81.0
HKD2_k127_3653571_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 436.0
HKD2_k127_3653571_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 346.0
HKD2_k127_3653571_2 Mur ligase middle domain K01932 - - 0.00000000000000000000000000000000000001106 156.0
HKD2_k127_3653571_3 deoxyhypusine monooxygenase activity - - - 0.00000005849 66.0
HKD2_k127_3661681_0 Histidine kinase K11527 - 2.7.13.3 1.1e-218 729.0
HKD2_k127_3661681_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000004442 128.0
HKD2_k127_3735171_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 489.0
HKD2_k127_3735171_1 HAD-superfamily phosphatase subfamily IIIC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 479.0
HKD2_k127_3735171_2 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003203 267.0
HKD2_k127_3735171_3 PFAM MscS Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000001671 253.0
HKD2_k127_3735171_4 Acetyltransferase (GNAT) domain - - - 0.0000000000002306 83.0
HKD2_k127_3735171_5 - - - - 0.00002307 55.0
HKD2_k127_3735171_6 AAA domain K10706 - - 0.00002835 50.0
HKD2_k127_3735801_0 Aldehyde dehydrogenase family - - - 2.029e-199 635.0
HKD2_k127_3735801_1 NMT1-like family K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 404.0
HKD2_k127_3735801_10 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily - - - 0.000000000000000000000000000000000000000000003255 166.0
HKD2_k127_3735801_11 PFAM ABC transporter related K02049,K15555 - - 0.000000000000000000000000000000000000005267 147.0
HKD2_k127_3735801_12 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000001409 64.0
HKD2_k127_3735801_2 ABC transporter K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 403.0
HKD2_k127_3735801_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 398.0
HKD2_k127_3735801_4 TIGRFAM pyrrolysine biosynthesis protein PylC K16181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 373.0
HKD2_k127_3735801_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 373.0
HKD2_k127_3735801_6 Binding-protein-dependent transport system inner membrane component K15554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 362.0
HKD2_k127_3735801_7 PFAM tRNA synthetase class II K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 297.0
HKD2_k127_3735801_8 FCD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000165 243.0
HKD2_k127_3735801_9 TIGRFAM pyrrolysine biosynthesis protein PylD K16182 - - 0.0000000000000000000000000000000000000000000000000000003261 203.0
HKD2_k127_3836469_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.654e-285 894.0
HKD2_k127_3836469_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 450.0
HKD2_k127_3836469_11 Belongs to the Fur family K03711 - - 0.0000000000000000000000007634 107.0
HKD2_k127_3836469_13 - - - - 0.000000000000003721 83.0
HKD2_k127_3836469_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 338.0
HKD2_k127_3836469_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 314.0
HKD2_k127_3836469_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002007 264.0
HKD2_k127_3836469_5 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.00000000000000000000000000000000000000000000000000000001322 207.0
HKD2_k127_3836469_6 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.00000000000000000000000000000000000000000000000000008601 202.0
HKD2_k127_3836469_7 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000007997 173.0
HKD2_k127_3836469_8 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000001081 161.0
HKD2_k127_3849595_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 514.0
HKD2_k127_3849595_1 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 406.0
HKD2_k127_3849595_2 PFAM Electron transfer flavoprotein alpha K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 411.0
HKD2_k127_3849595_3 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 367.0
HKD2_k127_3849595_4 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000001434 201.0
HKD2_k127_3849595_5 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000000000007134 162.0
HKD2_k127_3849595_6 Glycine-zipper domain - - - 0.00000000000000009603 82.0
HKD2_k127_3858893_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 6.4e-323 994.0
HKD2_k127_3858893_1 Iron only hydrogenase large subunit, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 316.0
HKD2_k127_3858893_10 DRTGG domain - - - 0.00000000000000000000001116 117.0
HKD2_k127_3858893_11 DRTGG domain - - - 0.00000000000000000001943 106.0
HKD2_k127_3858893_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000009993 226.0
HKD2_k127_3858893_3 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000001284 220.0
HKD2_k127_3858893_4 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000000000000007447 177.0
HKD2_k127_3858893_5 DRTGG domain - - - 0.000000000000000000000000000000000000000000004262 166.0
HKD2_k127_3858893_6 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.0000000000000000000000000000000000000001907 154.0
HKD2_k127_3858893_7 Histidine kinase - - - 0.00000000000000000000000000000000000005714 154.0
HKD2_k127_3858893_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000007433 113.0
HKD2_k127_3858893_9 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000000000000000000005858 108.0
HKD2_k127_3859991_0 PHP domain protein - - - 0.0 1120.0
HKD2_k127_3859991_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 527.0
HKD2_k127_3859991_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 292.0
HKD2_k127_3859991_11 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000000000000000000000009376 202.0
HKD2_k127_3859991_12 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000007291 197.0
HKD2_k127_3859991_13 Peptidase C13 family - - - 0.000000000000000000000000000000000000000000000001134 196.0
HKD2_k127_3859991_14 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000000154 168.0
HKD2_k127_3859991_15 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000001626 152.0
HKD2_k127_3859991_16 Domain of unknown function (DUF3783) - - - 0.000000000000000000000000000000000000279 145.0
HKD2_k127_3859991_17 Domain of unknown function (DUF4384) - - - 0.00000000000000000000000000000000015 141.0
HKD2_k127_3859991_18 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000008164 127.0
HKD2_k127_3859991_19 - - - - 0.000000006744 64.0
HKD2_k127_3859991_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 486.0
HKD2_k127_3859991_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 454.0
HKD2_k127_3859991_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 427.0
HKD2_k127_3859991_5 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 416.0
HKD2_k127_3859991_6 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 365.0
HKD2_k127_3859991_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 357.0
HKD2_k127_3859991_8 Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 355.0
HKD2_k127_3859991_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 308.0
HKD2_k127_3865982_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1489.0
HKD2_k127_3865982_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1061.0
HKD2_k127_3865982_10 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 449.0
HKD2_k127_3865982_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 441.0
HKD2_k127_3865982_12 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 451.0
HKD2_k127_3865982_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 426.0
HKD2_k127_3865982_14 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 428.0
HKD2_k127_3865982_15 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 409.0
HKD2_k127_3865982_16 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 401.0
HKD2_k127_3865982_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 380.0
HKD2_k127_3865982_18 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 381.0
HKD2_k127_3865982_19 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 377.0
HKD2_k127_3865982_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.426e-298 921.0
HKD2_k127_3865982_20 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 387.0
HKD2_k127_3865982_21 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 316.0
HKD2_k127_3865982_22 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 296.0
HKD2_k127_3865982_23 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 289.0
HKD2_k127_3865982_24 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005539 279.0
HKD2_k127_3865982_25 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009406 273.0
HKD2_k127_3865982_26 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000453 265.0
HKD2_k127_3865982_27 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007065 259.0
HKD2_k127_3865982_28 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000004292 254.0
HKD2_k127_3865982_29 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000001126 236.0
HKD2_k127_3865982_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.675e-227 708.0
HKD2_k127_3865982_30 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000000000000000000000000000000000000000000000000002149 241.0
HKD2_k127_3865982_31 HD domain K07023 - - 0.000000000000000000000000000000000000000000000000000000000000002408 222.0
HKD2_k127_3865982_32 - - - - 0.000000000000000000000000000000000000000000000000000000000009774 211.0
HKD2_k127_3865982_33 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000002155 216.0
HKD2_k127_3865982_34 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000001618 211.0
HKD2_k127_3865982_35 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000002135 185.0
HKD2_k127_3865982_36 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000004907 186.0
HKD2_k127_3865982_37 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000002615 161.0
HKD2_k127_3865982_38 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000002945 159.0
HKD2_k127_3865982_39 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000001863 154.0
HKD2_k127_3865982_4 NAD(P)H-binding K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 540.0
HKD2_k127_3865982_40 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000000002084 148.0
HKD2_k127_3865982_41 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000001706 140.0
HKD2_k127_3865982_42 energy transducer activity K03646,K03832 - - 0.000000000000000000000000000271 126.0
HKD2_k127_3865982_43 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000002812 116.0
HKD2_k127_3865982_44 regulatory protein, FmdB family - - - 0.0000000000000000000000000003546 116.0
HKD2_k127_3865982_45 Protein of unknown function (DUF721) - - - 0.00000000000000000000002507 102.0
HKD2_k127_3865982_46 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000005244 99.0
HKD2_k127_3865982_47 PilX N-terminal - - - 0.000000000000000000002145 106.0
HKD2_k127_3865982_49 Prokaryotic N-terminal methylation motif K08084 - - 0.0000000000001014 78.0
HKD2_k127_3865982_5 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 537.0
HKD2_k127_3865982_50 Prokaryotic N-terminal methylation motif K02671 - - 0.000000000002521 75.0
HKD2_k127_3865982_51 pilus assembly protein PilW - - - 0.00000000008293 72.0
HKD2_k127_3865982_53 Mitochondrial domain of unknown function (DUF1713) - - - 0.0000017 50.0
HKD2_k127_3865982_54 Type II transport protein GspH K08084 - - 0.00004878 52.0
HKD2_k127_3865982_55 Prokaryotic N-terminal methylation motif K02672 - - 0.0002845 52.0
HKD2_k127_3865982_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 510.0
HKD2_k127_3865982_7 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 509.0
HKD2_k127_3865982_8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 500.0
HKD2_k127_3865982_9 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 467.0
HKD2_k127_3881639_0 Major facilitator Superfamily K08218 - - 3.461e-222 700.0
HKD2_k127_3881639_1 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 512.0
HKD2_k127_3881639_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0001579 54.0
HKD2_k127_3881639_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0003635 53.0
HKD2_k127_3881639_2 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 408.0
HKD2_k127_3881639_3 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 321.0
HKD2_k127_3881639_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000005326 239.0
HKD2_k127_3881639_5 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000007845 240.0
HKD2_k127_3881639_6 arginine decarboxylase K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000001153 232.0
HKD2_k127_3881639_7 SMART Water Stress and Hypersensitive response - - - 0.000000000000000000000000000003734 125.0
HKD2_k127_3881639_8 DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0000000003071 61.0
HKD2_k127_3881639_9 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000001133 61.0
HKD2_k127_3886790_0 TRAP transporter, 4TM 12TM fusion protein - - - 4.233e-248 781.0
HKD2_k127_3886790_1 PFAM nickel-dependent hydrogenase large subunit K14126 - 1.8.98.5 6.145e-241 753.0
HKD2_k127_3886790_2 PFAM NADH ubiquinone oxidoreductase, 20 kDa subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 475.0
HKD2_k127_3886790_3 TRAP transporter, solute receptor (TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 361.0
HKD2_k127_3886790_4 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000001002 198.0
HKD2_k127_3886790_5 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000001644 199.0
HKD2_k127_3886790_6 glyoxylate reductase activity K00015 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.26 0.0000000000000000000000000000000000002975 156.0
HKD2_k127_3886790_7 Universal stress protein - - - 0.000000001694 67.0
HKD2_k127_3906957_0 aconitate hydratase K01681 - 4.2.1.3 1.457e-261 833.0
HKD2_k127_3906957_1 Malate/L-lactate dehydrogenase K00073 - 1.1.1.350 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 365.0
HKD2_k127_3906957_2 Phosphogluconate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 329.0
HKD2_k127_3906957_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000002064 221.0
HKD2_k127_3906957_4 transcriptional K03710 - - 0.0000000000000000000000000000001807 135.0
HKD2_k127_3943889_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 9.125e-253 794.0
HKD2_k127_3943889_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 569.0
HKD2_k127_3943889_2 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 447.0
HKD2_k127_3943889_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 299.0
HKD2_k127_3943889_4 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000004026 174.0
HKD2_k127_3943889_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000002089 168.0
HKD2_k127_3954322_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 579.0
HKD2_k127_3954322_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 509.0
HKD2_k127_3954322_2 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 458.0
HKD2_k127_3954322_3 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006552 275.0
HKD2_k127_3954322_4 Cold shock K03704 - - 0.000000000001544 71.0
HKD2_k127_3999608_0 dipeptide transport K02035 - - 1.101e-262 816.0
HKD2_k127_3999608_1 nitrogen compound transport K02033,K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 442.0
HKD2_k127_3999608_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 455.0
HKD2_k127_3999608_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 432.0
HKD2_k127_3999608_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 427.0
HKD2_k127_3999608_5 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001301 306.0
HKD2_k127_3999608_6 transmembrane signaling receptor activity K00575,K03406,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000004554 188.0
HKD2_k127_3999608_7 transmembrane signaling receptor activity K00575,K03406,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000118 184.0
HKD2_k127_4022932_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.0 1304.0
HKD2_k127_4022932_1 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.00000000000000000000000000000000354 131.0
HKD2_k127_4022932_2 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000003226 75.0
HKD2_k127_4036276_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1057.0
HKD2_k127_4036276_1 ABC transporter transmembrane region K06147,K18890 - - 2.264e-198 638.0
HKD2_k127_4036276_2 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 582.0
HKD2_k127_4036276_3 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 481.0
HKD2_k127_4044631_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1155.0
HKD2_k127_4044631_1 AMP-binding enzyme C-terminal domain K00666 - - 1.329e-285 890.0
HKD2_k127_4044631_10 cytochrome c nitrate reductase, small subunit K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000501 216.0
HKD2_k127_4044631_11 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000125 192.0
HKD2_k127_4044631_12 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000002882 99.0
HKD2_k127_4044631_13 Cyclic nucleotide-monophosphate binding domain - - - 0.000000001594 59.0
HKD2_k127_4044631_14 PFAM glycosyl transferase family 9 - - - 0.0003284 46.0
HKD2_k127_4044631_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 7.977e-228 722.0
HKD2_k127_4044631_3 Involved in beta-(1-- 2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP- binding domain (NBD) is responsible for energy generation K06147 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 1.143e-211 674.0
HKD2_k127_4044631_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.725e-211 689.0
HKD2_k127_4044631_5 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 552.0
HKD2_k127_4044631_6 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000986 407.0
HKD2_k127_4044631_7 MgtE intracellular - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 350.0
HKD2_k127_4044631_8 Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006106 266.0
HKD2_k127_4044631_9 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000001329 255.0
HKD2_k127_4062235_0 Carboxyl transferase domain K01615 - 4.1.1.70 9.098e-299 924.0
HKD2_k127_4062235_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 510.0
HKD2_k127_4062235_10 PFAM ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002788 258.0
HKD2_k127_4062235_11 PFAM peptidase K21471 - - 0.0000000000000000000000000000000000000000000000000000000007362 226.0
HKD2_k127_4062235_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000006701 209.0
HKD2_k127_4062235_13 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000001159 190.0
HKD2_k127_4062235_14 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000001345 168.0
HKD2_k127_4062235_15 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000000000000000000001771 167.0
HKD2_k127_4062235_16 Conserved carboxylase domain K01960 - 6.4.1.1 0.000000000000007962 79.0
HKD2_k127_4062235_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 490.0
HKD2_k127_4062235_3 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 479.0
HKD2_k127_4062235_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 474.0
HKD2_k127_4062235_5 ABC transporter K02013,K05776 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 400.0
HKD2_k127_4062235_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002917 277.0
HKD2_k127_4062235_7 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009073 273.0
HKD2_k127_4062235_8 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
HKD2_k127_4062235_9 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006336 267.0
HKD2_k127_41540_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 574.0
HKD2_k127_41540_1 Male sterility protein K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 527.0
HKD2_k127_41540_10 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.000000000000000000000000000000000000000000000000000000002944 211.0
HKD2_k127_41540_11 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000003436 195.0
HKD2_k127_41540_12 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000005109 99.0
HKD2_k127_41540_13 cellulase activity - - - 0.000000000000000001716 92.0
HKD2_k127_41540_14 - - - - 0.0000000000000002231 85.0
HKD2_k127_41540_15 - - - - 0.0000000000000003255 84.0
HKD2_k127_41540_16 - - - - 0.0000000000001056 76.0
HKD2_k127_41540_17 monooxygenase activity - - - 0.0000000000657 67.0
HKD2_k127_41540_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 482.0
HKD2_k127_41540_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 402.0
HKD2_k127_41540_4 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 362.0
HKD2_k127_41540_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 324.0
HKD2_k127_41540_6 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 297.0
HKD2_k127_41540_7 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001018 280.0
HKD2_k127_41540_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001978 266.0
HKD2_k127_41540_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000003384 235.0
HKD2_k127_4237132_0 Heat shock 70 kDa protein K04043 - - 0.0 1005.0
HKD2_k127_4237132_1 ABC transporter K02017,K11072 - 3.6.3.29,3.6.3.31 2.469e-229 727.0
HKD2_k127_4237132_10 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000471 95.0
HKD2_k127_4237132_12 Heavy-metal resistance K07803 - - 0.000009288 53.0
HKD2_k127_4237132_2 FAD dependent oxidoreductase K00111 - 1.1.5.3 2.582e-196 624.0
HKD2_k127_4237132_3 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 510.0
HKD2_k127_4237132_4 Glycerol-3-phosphate dehydrogenase, anaerobic, B subunit K00112 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 397.0
HKD2_k127_4237132_5 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 342.0
HKD2_k127_4237132_6 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 299.0
HKD2_k127_4237132_7 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
HKD2_k127_4237132_8 - - - - 0.00000000000000000000000000000000000000000000000000000000007284 213.0
HKD2_k127_4237132_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000003711 153.0
HKD2_k127_4247366_0 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 326.0
HKD2_k127_4247366_1 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000424 258.0
HKD2_k127_4247366_2 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000000000000000000000000000002113 227.0
HKD2_k127_4247366_3 Type III effector Hrp-dependent K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000001754 181.0
HKD2_k127_4247366_4 Protein of unknown function (DUF1571) - - - 0.00000000000000000000000000000000000000000002696 185.0
HKD2_k127_4247366_5 Transcription elongation factor, GreA/GreB, C-term - - - 0.000000000000000000000000000000000000002044 165.0
HKD2_k127_4247366_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000001065 54.0
HKD2_k127_4250770_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 508.0
HKD2_k127_4250770_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 490.0
HKD2_k127_4250770_11 - - - - 0.0000001566 62.0
HKD2_k127_4250770_12 Polyketide cyclase dehydrase - - - 0.0006191 46.0
HKD2_k127_4250770_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 472.0
HKD2_k127_4250770_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 461.0
HKD2_k127_4250770_4 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 403.0
HKD2_k127_4250770_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 391.0
HKD2_k127_4250770_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 376.0
HKD2_k127_4250770_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000381 285.0
HKD2_k127_4250770_8 Prephenate dehydrogenase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000005082 265.0
HKD2_k127_4250770_9 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000002747 72.0
HKD2_k127_4275051_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.504e-244 759.0
HKD2_k127_4275051_1 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 354.0
HKD2_k127_4275051_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 346.0
HKD2_k127_4275051_3 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000001325 235.0
HKD2_k127_4275051_4 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000005332 224.0
HKD2_k127_4275051_5 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000005536 214.0
HKD2_k127_4275051_6 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000004633 143.0
HKD2_k127_4286793_0 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 506.0
HKD2_k127_4286793_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 524.0
HKD2_k127_4286793_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 418.0
HKD2_k127_4286793_3 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003213 283.0
HKD2_k127_4286793_4 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000001867 146.0
HKD2_k127_4286793_5 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000004103 81.0
HKD2_k127_4324551_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 522.0
HKD2_k127_4324551_1 Protein conserved in bacteria K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 391.0
HKD2_k127_4324551_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000001798 228.0
HKD2_k127_4324551_3 PrpF protein K09788 - - 0.00000000000000000000000000000000000000000000000000001364 191.0
HKD2_k127_4324551_4 Tripartite tricarboxylate transporter TctB family - - - 0.000000008622 64.0
HKD2_k127_4342512_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 486.0
HKD2_k127_4342512_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 347.0
HKD2_k127_4342512_2 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000001313 205.0
HKD2_k127_4342512_3 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000007778 182.0
HKD2_k127_4342512_4 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K21992 - - 0.000000000000000000000000000000000000007205 154.0
HKD2_k127_4342512_5 Tetratricopeptide repeat - - - 0.00000000000000000000002281 118.0
HKD2_k127_436227_0 SMART Elongator protein 3 MiaB NifB - - - 1.339e-305 960.0
HKD2_k127_436227_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 588.0
HKD2_k127_436227_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 301.0
HKD2_k127_4424909_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1770.0
HKD2_k127_4424909_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.857e-259 810.0
HKD2_k127_4424909_10 PFAM cytochrome c class III - - - 0.000000000000000000000000000001853 124.0
HKD2_k127_4424909_2 4Fe-4S dicluster domain - - - 1.33e-225 705.0
HKD2_k127_4424909_3 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 517.0
HKD2_k127_4424909_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 476.0
HKD2_k127_4424909_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 410.0
HKD2_k127_4424909_6 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
HKD2_k127_4424909_7 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009823 276.0
HKD2_k127_4424909_8 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000004432 162.0
HKD2_k127_4424909_9 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000007599 138.0
HKD2_k127_445539_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.0 1080.0
HKD2_k127_445539_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 9.4e-323 1000.0
HKD2_k127_445539_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000006289 143.0
HKD2_k127_445539_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000009289 137.0
HKD2_k127_445539_12 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000003698 96.0
HKD2_k127_445539_2 PFAM Type II secretion system protein E K02454,K02652 - - 4.714e-219 698.0
HKD2_k127_445539_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 459.0
HKD2_k127_445539_4 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 372.0
HKD2_k127_445539_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005177 286.0
HKD2_k127_445539_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000006769 274.0
HKD2_k127_445539_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000851 248.0
HKD2_k127_445539_8 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005376 258.0
HKD2_k127_445539_9 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000003622 211.0
HKD2_k127_4461118_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1007.0
HKD2_k127_4461118_1 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 5.086e-305 955.0
HKD2_k127_4461118_10 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001448 257.0
HKD2_k127_4461118_11 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008477 257.0
HKD2_k127_4461118_12 PFAM AsmA family protein K07290 - - 0.000000000000000000000000000000000000000000000000000001597 208.0
HKD2_k127_4461118_13 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000004803 196.0
HKD2_k127_4461118_14 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000008798 186.0
HKD2_k127_4461118_15 C-terminal region of aryl-sulfatase - - - 0.00000000000000000000000000000000000000000000002741 172.0
HKD2_k127_4461118_17 VanZ like family - - - 0.000000000000000000008315 98.0
HKD2_k127_4461118_18 AsmA family K07289,K07290 - - 0.0000000000004476 78.0
HKD2_k127_4461118_19 helix_turn_helix, Lux Regulon K02479,K07692 - - 0.00000000000115 73.0
HKD2_k127_4461118_2 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 1.188e-257 803.0
HKD2_k127_4461118_3 sarcosine oxidase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 535.0
HKD2_k127_4461118_4 SMART molybdopterin oxidoreductase Fe4S4 region, NADH ubiquinone oxidoreductase, subunit G, iron-sulfur binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 518.0
HKD2_k127_4461118_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 409.0
HKD2_k127_4461118_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 394.0
HKD2_k127_4461118_7 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 398.0
HKD2_k127_4461118_8 Histidine kinase K07683 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 379.0
HKD2_k127_4461118_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 317.0
HKD2_k127_4479209_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 570.0
HKD2_k127_4479209_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 566.0
HKD2_k127_4479209_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 533.0
HKD2_k127_4479209_3 Psort location CytoplasmicMembrane, score 10.00 K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 527.0
HKD2_k127_4479209_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 314.0
HKD2_k127_4479209_5 PFAM GCN5-related N-acetyltransferase K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000007651 197.0
HKD2_k127_4479209_6 single-species biofilm formation - - - 0.00000000000000000000000005158 115.0
HKD2_k127_4479209_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000264 106.0
HKD2_k127_4479209_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000004815 72.0
HKD2_k127_4479209_9 Tripartite tricarboxylate transporter TctB family - - - 0.0001216 51.0
HKD2_k127_4482023_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.791e-208 653.0
HKD2_k127_4482023_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.323e-202 643.0
HKD2_k127_4482023_2 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 437.0
HKD2_k127_4482023_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 353.0
HKD2_k127_4482023_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 346.0
HKD2_k127_4482023_5 Essential cell division protein K03589 - - 0.000000000000000000000000000000000000000008851 176.0
HKD2_k127_4482023_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000002986 82.0
HKD2_k127_4592108_0 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 623.0
HKD2_k127_4592108_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 511.0
HKD2_k127_4592108_2 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 386.0
HKD2_k127_4592108_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00003,K01139 - 1.1.1.3,2.7.6.5,3.1.7.2 0.000000000003094 68.0
HKD2_k127_4612950_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1386.0
HKD2_k127_4612950_1 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 598.0
HKD2_k127_4612950_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 358.0
HKD2_k127_4612950_3 PFAM ABC 3 transport family K09816,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000003927 216.0
HKD2_k127_4612950_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000004914 189.0
HKD2_k127_4612950_5 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000000009139 166.0
HKD2_k127_4645221_0 Elongator protein 3, MiaB family, Radical SAM - - - 5.948e-222 693.0
HKD2_k127_4645221_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 322.0
HKD2_k127_4645221_2 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000244 229.0
HKD2_k127_4645221_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000008008 198.0
HKD2_k127_4645221_4 Outer membrane lipoprotein carrier protein LolA - - - 0.00000000000000000000000000000000000001016 154.0
HKD2_k127_4645221_5 - - - - 0.00000000000000000000000000000002338 138.0
HKD2_k127_4645221_6 dehydratase - - - 0.000000000000000000000002936 108.0
HKD2_k127_4645221_7 acyl carrier protein K02078 - - 0.00000000000000000000005277 104.0
HKD2_k127_4662728_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 490.0
HKD2_k127_4662728_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 376.0
HKD2_k127_4662728_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 310.0
HKD2_k127_4662728_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000001076 183.0
HKD2_k127_4662728_4 - - - - 0.0000000000000000005022 89.0
HKD2_k127_472170_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.438e-248 775.0
HKD2_k127_472170_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 8.269e-243 766.0
HKD2_k127_472170_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000000000015 146.0
HKD2_k127_472170_11 protein-disulfide reductase activity - - - 0.0000000000000000000000000000000006751 135.0
HKD2_k127_472170_12 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000001475 115.0
HKD2_k127_472170_13 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05574 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000679 108.0
HKD2_k127_472170_14 lipolytic protein G-D-S-L family - - - 0.0000000000000000000004853 102.0
HKD2_k127_472170_15 Multidrug transporter - - - 0.000000001073 65.0
HKD2_k127_472170_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 546.0
HKD2_k127_472170_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 448.0
HKD2_k127_472170_4 Flagellar motor switch protein FliN K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 352.0
HKD2_k127_472170_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004665 282.0
HKD2_k127_472170_6 - - - - 0.0000000000000000000000000000000000000000000000000000000001519 211.0
HKD2_k127_472170_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000003472 186.0
HKD2_k127_472170_8 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000001016 182.0
HKD2_k127_472170_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000004408 156.0
HKD2_k127_4764485_0 AMP-binding enzyme K22319 - 6.1.3.1 6.33e-219 694.0
HKD2_k127_4764485_1 PFAM 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III K22317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 448.0
HKD2_k127_4764485_2 3-beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 419.0
HKD2_k127_4764485_3 Extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
HKD2_k127_4764485_4 alpha/beta hydrolase fold K01563,K22318 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 352.0
HKD2_k127_4764485_5 ABC transporter K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000002446 248.0
HKD2_k127_4764485_6 Sensory domain found in PocR - - - 0.0000000000000000000000000000000000000000000000008052 193.0
HKD2_k127_481352_0 Glycine radical K00656 - 2.3.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 591.0
HKD2_k127_481352_1 FCD - - - 0.000000000000000000000000000000000000000000000000000009656 199.0
HKD2_k127_4868873_0 Histidine ammonia-lyase K01745 - 4.3.1.3 6.485e-226 716.0
HKD2_k127_4868873_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K18847 - 2.1.2.1,2.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 533.0
HKD2_k127_4868873_2 PFAM Mammalian cell entry related K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 457.0
HKD2_k127_4868873_3 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 332.0
HKD2_k127_4868873_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001719 298.0
HKD2_k127_4868873_5 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006563 254.0
HKD2_k127_4868873_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000004163 217.0
HKD2_k127_4868873_7 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000001748 123.0
HKD2_k127_4944296_0 Putative serine dehydratase domain K20757 - 4.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 448.0
HKD2_k127_4944296_1 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000001371 175.0
HKD2_k127_4944296_2 Domain of unknown function (DUF4382) - - - 0.00000000000000000133 91.0
HKD2_k127_4972038_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 380.0
HKD2_k127_4972038_1 Polysaccharide deacetylase K11931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 313.0
HKD2_k127_4972038_2 - - - - 0.00000000000000000000000000000000000002899 162.0
HKD2_k127_4972038_3 - - - - 0.0000000000000002105 90.0
HKD2_k127_4980565_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007105 293.0
HKD2_k127_4980565_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000000000001059 209.0
HKD2_k127_4980565_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000004748 127.0
HKD2_k127_4980565_3 - - - - 0.000000005847 69.0
HKD2_k127_4998434_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 593.0
HKD2_k127_4998434_1 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 501.0
HKD2_k127_4998434_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000008207 188.0
HKD2_k127_4998434_3 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000001364 149.0
HKD2_k127_4998434_4 Heavy-metal resistance K07803 - - 0.00000000000000001204 90.0
HKD2_k127_4998434_5 - - - - 0.00002157 57.0
HKD2_k127_5034695_0 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 584.0
HKD2_k127_5034695_1 SMART ATP-binding region ATPase domain protein - - - 0.000000000000000002748 96.0
HKD2_k127_5034695_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000001993 68.0
HKD2_k127_5078883_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 580.0
HKD2_k127_5078883_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 545.0
HKD2_k127_5078883_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 538.0
HKD2_k127_5078883_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 394.0
HKD2_k127_5078883_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 337.0
HKD2_k127_5078883_5 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000004541 121.0
HKD2_k127_5078883_6 cell division protein FtsL - - - 0.00000000000000000004592 94.0
HKD2_k127_5078883_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000002364 81.0
HKD2_k127_5078883_8 Polysaccharide biosynthesis protein - - - 0.000006351 53.0
HKD2_k127_5131173_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 286.0
HKD2_k127_5131173_1 carboxylase K01965,K01968 - 6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000006824 228.0
HKD2_k127_5131173_2 - - - - 0.000000000000000000000000000000000000000000000000000006977 213.0
HKD2_k127_5131173_3 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000005729 199.0
HKD2_k127_5131173_4 rRNA (adenine-N6,N6-)-dimethyltransferase activity K02528,K20444 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000001874 166.0
HKD2_k127_5131173_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000002777 124.0
HKD2_k127_5131173_6 domain protein - - - 0.000000000000000000000004983 107.0
HKD2_k127_5159304_0 PFAM ABC transporter K06158 - - 1.511e-236 748.0
HKD2_k127_5159304_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 467.0
HKD2_k127_5159304_2 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 454.0
HKD2_k127_5159304_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 337.0
HKD2_k127_5159304_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000001421 260.0
HKD2_k127_5159304_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000108 200.0
HKD2_k127_5159304_6 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000000005483 181.0
HKD2_k127_5159304_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000007444 175.0
HKD2_k127_5159304_8 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000001032 120.0
HKD2_k127_5171132_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 4.695e-202 647.0
HKD2_k127_5171132_1 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 363.0
HKD2_k127_5171132_2 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 374.0
HKD2_k127_5171132_3 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 308.0
HKD2_k127_5171132_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000001061 144.0
HKD2_k127_5171132_5 transcriptional regulator K13641 - - 0.000000002223 60.0
HKD2_k127_5176926_0 Belongs to the enoyl-CoA hydratase isomerase family K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 4.899e-292 914.0
HKD2_k127_5176926_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 540.0
HKD2_k127_5176926_2 PFAM aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 509.0
HKD2_k127_5176926_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 445.0
HKD2_k127_5176926_4 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 320.0
HKD2_k127_5176926_5 Protein of unknown function (DUF1847) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 299.0
HKD2_k127_5176926_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000002778 226.0
HKD2_k127_5176926_7 Domain of unknown function (DUF4442) K02614 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000007528 91.0
HKD2_k127_5217085_0 D-galactarate dehydratase / Altronate hydrolase, C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 613.0
HKD2_k127_5217085_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 531.0
HKD2_k127_5217085_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 483.0
HKD2_k127_5217085_3 ABC-type branched-chain amino acid transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 409.0
HKD2_k127_5217085_4 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 398.0
HKD2_k127_5217085_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001992 275.0
HKD2_k127_5217085_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006027 260.0
HKD2_k127_5217085_7 transcriptional regulator - - - 0.00000000000000000000000001628 121.0
HKD2_k127_5261693_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 5.945e-218 691.0
HKD2_k127_5261693_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000001084 207.0
HKD2_k127_5261693_2 TIGRFAM phosphocarrier, HPr family K11189 - - 0.0000000000009194 74.0
HKD2_k127_5261693_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000005574 58.0
HKD2_k127_5285067_0 PFAM Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 505.0
HKD2_k127_5285067_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 396.0
HKD2_k127_5285067_2 dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000000000000000002994 204.0
HKD2_k127_5285067_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000006952 158.0
HKD2_k127_5285067_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000006703 78.0
HKD2_k127_533900_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.513e-260 824.0
HKD2_k127_533900_1 FAD linked oxidase - - - 5.188e-216 680.0
HKD2_k127_533900_10 - - - - 0.000000000000000000000000000000000000000000002934 173.0
HKD2_k127_533900_11 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000003323 164.0
HKD2_k127_533900_12 PFAM transport-associated - - - 0.000000000000000000000000009258 125.0
HKD2_k127_533900_13 KH domain K06960 - - 0.00000000000000000000218 97.0
HKD2_k127_533900_14 Two component transcriptional regulator (LuxR family - - - 0.000000000000001345 91.0
HKD2_k127_533900_15 - - - - 0.0000005593 55.0
HKD2_k127_533900_2 PFAM Aldehyde dehydrogenase K00128,K00131,K00135,K00140 - 1.2.1.16,1.2.1.18,1.2.1.20,1.2.1.27,1.2.1.3,1.2.1.79,1.2.1.9 9.372e-207 657.0
HKD2_k127_533900_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 530.0
HKD2_k127_533900_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 460.0
HKD2_k127_533900_5 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 286.0
HKD2_k127_533900_6 decarboxylase K22213 - 4.1.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003314 286.0
HKD2_k127_533900_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004786 274.0
HKD2_k127_533900_8 histidine kinase A domain protein K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000003591 252.0
HKD2_k127_533900_9 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000006208 214.0
HKD2_k127_5350438_0 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 1e-323 1012.0
HKD2_k127_5350438_1 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 3.699e-216 693.0
HKD2_k127_5350438_10 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000001211 166.0
HKD2_k127_5350438_11 response regulator - - - 0.00000000000000000000000000000000000000000003081 168.0
HKD2_k127_5350438_12 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000002254 153.0
HKD2_k127_5350438_13 PFAM response regulator receiver - - - 0.0000000000000006027 85.0
HKD2_k127_5350438_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 606.0
HKD2_k127_5350438_3 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 610.0
HKD2_k127_5350438_4 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 584.0
HKD2_k127_5350438_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006691 467.0
HKD2_k127_5350438_6 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 377.0
HKD2_k127_5350438_7 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 346.0
HKD2_k127_5350438_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003887 253.0
HKD2_k127_5350438_9 SMART metal-dependent phosphohydrolase, HD region K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
HKD2_k127_5353145_0 DNA segregation ATPase, FtsK SpoIIIE family K03466 - - 1.319e-252 796.0
HKD2_k127_5353145_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 529.0
HKD2_k127_5353145_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 291.0
HKD2_k127_5353145_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000002571 233.0
HKD2_k127_5353145_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000008213 189.0
HKD2_k127_5353145_5 - - - - 0.00000000000000000000000000000001326 137.0
HKD2_k127_5353145_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000005492 119.0
HKD2_k127_5353145_7 - - - - 0.00000003809 65.0
HKD2_k127_5355423_0 Tripartite tricarboxylate transporter TctA family K07793 - - 2.715e-253 788.0
HKD2_k127_5355423_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 616.0
HKD2_k127_5355423_2 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 457.0
HKD2_k127_5355423_3 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 325.0
HKD2_k127_5355423_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 300.0
HKD2_k127_5355423_5 Cytochrome b/b6/petB K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000001065 233.0
HKD2_k127_5355423_6 membrane K07794 - - 0.0000000000000000000000000000000000000000000000000008936 188.0
HKD2_k127_5356511_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1119.0
HKD2_k127_5356511_1 RNA binding S1 domain protein K06959 - - 3.069e-302 946.0
HKD2_k127_5356511_10 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 454.0
HKD2_k127_5356511_11 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 406.0
HKD2_k127_5356511_12 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 318.0
HKD2_k127_5356511_13 Belongs to the TtcA family K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 314.0
HKD2_k127_5356511_14 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 295.0
HKD2_k127_5356511_15 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 296.0
HKD2_k127_5356511_16 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004222 270.0
HKD2_k127_5356511_17 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000007879 263.0
HKD2_k127_5356511_18 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000004423 252.0
HKD2_k127_5356511_19 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000001648 228.0
HKD2_k127_5356511_2 Carbon starvation protein CstA K06200 - - 4.161e-279 871.0
HKD2_k127_5356511_20 NGG1p interacting factor 3 K22391 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000001806 235.0
HKD2_k127_5356511_21 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000002947 228.0
HKD2_k127_5356511_22 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000001736 226.0
HKD2_k127_5356511_23 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000001716 192.0
HKD2_k127_5356511_24 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000009353 188.0
HKD2_k127_5356511_25 PFAM peptidase M22 glycoprotease K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000001767 172.0
HKD2_k127_5356511_26 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000006843 151.0
HKD2_k127_5356511_27 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.0000000000000000000000000000000229 127.0
HKD2_k127_5356511_28 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000002013 98.0
HKD2_k127_5356511_29 - - - - 0.0000000000000001538 80.0
HKD2_k127_5356511_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.465e-232 737.0
HKD2_k127_5356511_30 - - - - 0.0000000000001087 77.0
HKD2_k127_5356511_4 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 8.317e-223 705.0
HKD2_k127_5356511_5 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 8.77e-201 629.0
HKD2_k127_5356511_6 Dynamin family - - - 1.716e-195 634.0
HKD2_k127_5356511_7 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 572.0
HKD2_k127_5356511_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 542.0
HKD2_k127_5356511_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 518.0
HKD2_k127_5368551_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10,2.2.1.8 0.0 1118.0
HKD2_k127_5368551_1 Domain of unknown function (DUF1929) - - - 0.0 1110.0
HKD2_k127_5368551_10 Von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 600.0
HKD2_k127_5368551_11 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 516.0
HKD2_k127_5368551_12 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 498.0
HKD2_k127_5368551_13 Animal haem peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 489.0
HKD2_k127_5368551_14 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 421.0
HKD2_k127_5368551_15 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 417.0
HKD2_k127_5368551_16 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 377.0
HKD2_k127_5368551_17 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 369.0
HKD2_k127_5368551_18 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 361.0
HKD2_k127_5368551_19 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 344.0
HKD2_k127_5368551_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.29e-275 891.0
HKD2_k127_5368551_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 298.0
HKD2_k127_5368551_21 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001234 275.0
HKD2_k127_5368551_22 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
HKD2_k127_5368551_23 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001997 260.0
HKD2_k127_5368551_24 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000681 262.0
HKD2_k127_5368551_25 pfam nlp p60 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001371 250.0
HKD2_k127_5368551_26 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003262 240.0
HKD2_k127_5368551_27 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000004318 235.0
HKD2_k127_5368551_28 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000001422 238.0
HKD2_k127_5368551_29 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000008701 222.0
HKD2_k127_5368551_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.306e-234 736.0
HKD2_k127_5368551_30 von Willebrand factor (vWF) type A domain K03286 - - 0.0000000000000000000000000000000000000000000000000000001123 208.0
HKD2_k127_5368551_31 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000001803 194.0
HKD2_k127_5368551_32 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000003344 198.0
HKD2_k127_5368551_33 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000005419 169.0
HKD2_k127_5368551_34 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000007058 181.0
HKD2_k127_5368551_35 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000002916 169.0
HKD2_k127_5368551_36 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000005916 166.0
HKD2_k127_5368551_37 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000007733 166.0
HKD2_k127_5368551_38 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000003004 157.0
HKD2_k127_5368551_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.197e-232 741.0
HKD2_k127_5368551_40 - - - - 0.000000000000000000000000000000551 126.0
HKD2_k127_5368551_41 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000008051 109.0
HKD2_k127_5368551_42 4Fe-4S single cluster domain K05337 - - 0.00000000000000000000006239 99.0
HKD2_k127_5368551_43 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000007051 99.0
HKD2_k127_5368551_44 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001478 83.0
HKD2_k127_5368551_45 Nitroreductase family - - - 0.00000000000001706 79.0
HKD2_k127_5368551_46 - - - - 0.00000000000003301 74.0
HKD2_k127_5368551_47 - - - - 0.000000005452 67.0
HKD2_k127_5368551_49 Domain of unknown function (DUF4124) - - - 0.000004248 56.0
HKD2_k127_5368551_5 HELICc2 K07464,K10844 - 3.1.12.1,3.6.4.12 1.258e-228 731.0
HKD2_k127_5368551_50 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00002135 48.0
HKD2_k127_5368551_51 LysM domain M23 M37 peptidase domain protein K06194 - - 0.00003546 55.0
HKD2_k127_5368551_52 Domain of unknown function (DUF4124) - - - 0.0001926 51.0
HKD2_k127_5368551_53 Sh3 type 3 domain protein K01448 - 3.5.1.28 0.0004899 49.0
HKD2_k127_5368551_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.363e-200 632.0
HKD2_k127_5368551_7 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.676e-196 618.0
HKD2_k127_5368551_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 598.0
HKD2_k127_5368551_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 586.0
HKD2_k127_5383389_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002731 282.0
HKD2_k127_5383389_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000874 220.0
HKD2_k127_5383389_2 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000001358 178.0
HKD2_k127_5383389_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000518 156.0
HKD2_k127_5383389_4 PFAM GDSL-like Lipase Acylhydrolase - - - 0.000000000000000000000000000155 129.0
HKD2_k127_5383389_5 - - - - 0.0000000000000000000004427 103.0
HKD2_k127_5383389_6 Putative regulatory protein - - - 0.0000000000000003099 80.0
HKD2_k127_5383389_7 Domain of unknown function (DUF4124) - - - 0.0003659 50.0
HKD2_k127_5399066_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 361.0
HKD2_k127_5399066_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004402 275.0
HKD2_k127_5399066_2 PFAM MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000003485 180.0
HKD2_k127_5399066_3 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000008136 145.0
HKD2_k127_5399066_4 50S ribosome-binding GTPase - - - 0.0000000000000297 85.0
HKD2_k127_5465960_0 UvrD REP helicase K03657 - 3.6.4.12 3.33e-216 691.0
HKD2_k127_5465960_1 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 481.0
HKD2_k127_5465960_2 TIGRFAM cytochrome c-type biogenesis protein CcsB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 421.0
HKD2_k127_5516930_0 ATP synthase alpha beta family, nucleotide-binding domain K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 600.0
HKD2_k127_5516930_1 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 481.0
HKD2_k127_5516930_10 Flagellar basal body rod FlgEFG protein C-terminal K02388 - - 0.0000000000000000000000000000000000000000006017 180.0
HKD2_k127_5516930_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000001366 109.0
HKD2_k127_5516930_12 Flagellar assembly protein FliH K02411 - - 0.000000000000006939 84.0
HKD2_k127_5516930_13 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000001699 73.0
HKD2_k127_5516930_14 bacterial-type flagellum organization K02413 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000003286 61.0
HKD2_k127_5516930_15 Flagellar hook-length control protein K02414 - - 0.0000005219 63.0
HKD2_k127_5516930_2 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 452.0
HKD2_k127_5516930_3 Bacterial regulatory protein, Fis family K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 377.0
HKD2_k127_5516930_4 flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 298.0
HKD2_k127_5516930_5 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005307 279.0
HKD2_k127_5516930_6 basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000005251 203.0
HKD2_k127_5516930_7 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000003204 192.0
HKD2_k127_5516930_8 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0000000000000000000000000000000000000000000000000004544 201.0
HKD2_k127_5516930_9 Chemotaxis phosphatase CheX K03409 - - 0.0000000000000000000000000000000000000000001563 163.0
HKD2_k127_5557796_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 597.0
HKD2_k127_5557796_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 541.0
HKD2_k127_5557796_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 462.0
HKD2_k127_5557796_3 acyl-CoA synthetase - - - 0.000000000000000000000000000000000000006211 150.0
HKD2_k127_5557796_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000001997 161.0
HKD2_k127_5557796_5 Transcriptional regulator K03724 - - 0.000000000000000000000000000001919 126.0
HKD2_k127_5557796_6 Protein of unknown function (DUF3426) - - - 0.0000001818 61.0
HKD2_k127_5566328_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 336.0
HKD2_k127_5566328_1 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002692 258.0
HKD2_k127_5566328_2 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000001474 189.0
HKD2_k127_5580596_0 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 535.0
HKD2_k127_5580596_1 TIGRFAM phenazine biosynthesis protein PhzF family - - - 0.00000000000000000000002723 100.0
HKD2_k127_5580596_2 Peptidase dimerisation domain - - - 0.0000000000000003261 79.0
HKD2_k127_5583225_0 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 0.0 1003.0
HKD2_k127_5583225_1 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 468.0
HKD2_k127_5583225_2 PFAM Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.00000000000000000002236 92.0
HKD2_k127_562140_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1259.0
HKD2_k127_562140_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 316.0
HKD2_k127_562140_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002452 283.0
HKD2_k127_562140_3 Guanylyl transferase CofC like K09931 - - 0.000000005963 58.0
HKD2_k127_5662445_0 PFAM Coenzyme A transferase K01040 - 2.8.3.12 3.184e-280 870.0
HKD2_k127_5662445_1 Tripartite tricarboxylate transporter TctA family K07793 - - 4.426e-235 736.0
HKD2_k127_5662445_10 histidine kinase A domain protein - - - 0.00000005281 59.0
HKD2_k127_5662445_2 Aldehyde dehydrogenase family K13922,K15515 - 1.2.1.81,1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 555.0
HKD2_k127_5662445_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 499.0
HKD2_k127_5662445_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 439.0
HKD2_k127_5662445_5 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000007638 270.0
HKD2_k127_5662445_6 GntR family - - - 0.0000000000000000000000000000000000000000000000000000000000001251 220.0
HKD2_k127_5662445_7 - - - - 0.000000000000000000000000000000000000000002244 160.0
HKD2_k127_5662445_8 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000000002394 143.0
HKD2_k127_5662445_9 - - - - 0.000000000000000000001648 101.0
HKD2_k127_5679790_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 6.097e-211 668.0
HKD2_k127_5679790_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 602.0
HKD2_k127_5679790_10 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 316.0
HKD2_k127_5679790_11 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 301.0
HKD2_k127_5679790_12 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000135 293.0
HKD2_k127_5679790_13 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001343 250.0
HKD2_k127_5679790_14 HpcH/HpaI aldolase/citrate lyase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000006112 244.0
HKD2_k127_5679790_15 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000002939 233.0
HKD2_k127_5679790_16 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
HKD2_k127_5679790_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.00000000000000000000000000000000000000000000000000000000004062 210.0
HKD2_k127_5679790_18 nitric oxide dioxygenase activity K00528,K05784 GO:0000166,GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004324,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006000,GO:0006001,GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010035,GO:0016043,GO:0016052,GO:0016226,GO:0016491,GO:0016730,GO:0016731,GO:0019318,GO:0019320,GO:0022607,GO:0031163,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051186,GO:0055114,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901575,GO:1901700 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000006926 203.0
HKD2_k127_5679790_19 - - - - 0.000000000000000000000000000000000000000000000000000114 189.0
HKD2_k127_5679790_2 PFAM Peptidase M29, aminopeptidase II K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 456.0
HKD2_k127_5679790_20 PAS domain - - - 0.000000000000000000000000000000000004179 159.0
HKD2_k127_5679790_21 major outer membrane lipoprotein - - - 0.0000000000000000000000000000002349 138.0
HKD2_k127_5679790_22 - - - - 0.0000000000000000000000000000009969 137.0
HKD2_k127_5679790_23 cheY-homologous receiver domain - - - 0.000000000000000000000000002002 117.0
HKD2_k127_5679790_24 - - - - 0.000000000000000000000000005113 113.0
HKD2_k127_5679790_25 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000007295 79.0
HKD2_k127_5679790_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 437.0
HKD2_k127_5679790_4 PFAM OsmC family protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 425.0
HKD2_k127_5679790_5 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 398.0
HKD2_k127_5679790_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 401.0
HKD2_k127_5679790_7 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 359.0
HKD2_k127_5679790_8 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 334.0
HKD2_k127_5679790_9 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 319.0
HKD2_k127_5714607_0 Conserved hypothetical protein 698 - - - 5.54e-308 952.0
HKD2_k127_5714607_1 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 542.0
HKD2_k127_5714607_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 442.0
HKD2_k127_5714607_3 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 350.0
HKD2_k127_5714607_4 PFAM response regulator receiver K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 335.0
HKD2_k127_5714607_5 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 303.0
HKD2_k127_5714607_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001634 234.0
HKD2_k127_5714607_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000216 164.0
HKD2_k127_5714607_8 - - - - 0.00009318 54.0
HKD2_k127_5753956_0 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 573.0
HKD2_k127_5753956_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 533.0
HKD2_k127_5753956_2 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 394.0
HKD2_k127_5753956_3 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 391.0
HKD2_k127_5753956_4 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 287.0
HKD2_k127_5753956_5 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 292.0
HKD2_k127_5753956_6 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.000000000000000000000000000000000000000000000000000002455 199.0
HKD2_k127_5753956_7 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K19594 - - 0.00000000001161 66.0
HKD2_k127_5826623_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 4.516e-271 852.0
HKD2_k127_5826623_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.733e-248 778.0
HKD2_k127_5826623_10 PFAM Cold-shock K03704 - - 0.0000000000000000000000000000001029 126.0
HKD2_k127_5826623_11 PFAM toluene tolerance family protein K07323 - - 0.000000008114 61.0
HKD2_k127_5826623_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 553.0
HKD2_k127_5826623_3 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 519.0
HKD2_k127_5826623_4 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 379.0
HKD2_k127_5826623_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 325.0
HKD2_k127_5826623_6 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 323.0
HKD2_k127_5826623_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004285 242.0
HKD2_k127_5826623_8 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000009725 209.0
HKD2_k127_5826623_9 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000001824 188.0
HKD2_k127_5839770_0 Amidohydrolase family K01485 - 3.5.4.1 4.48e-201 649.0
HKD2_k127_5839770_1 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 576.0
HKD2_k127_5839770_2 ABC-type transport system, periplasmic component surface lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 471.0
HKD2_k127_5839770_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 437.0
HKD2_k127_5839770_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 409.0
HKD2_k127_5839770_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 330.0
HKD2_k127_5839770_6 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000001171 182.0
HKD2_k127_5869038_0 Protein of unknown function (DUF1254) - - - 1.346e-228 716.0
HKD2_k127_5869038_1 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 617.0
HKD2_k127_5990392_0 FtsX-like permease family - - - 0.0 1600.0
HKD2_k127_5990392_1 PFAM Oligopeptide transporter OPT superfamily - - - 0.0 1105.0
HKD2_k127_5990392_10 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000001027 199.0
HKD2_k127_5990392_11 - - - - 0.0000000000000000000000000000000000000000000000002126 183.0
HKD2_k127_5990392_12 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000003005 158.0
HKD2_k127_5990392_13 STAS domain K04749 - - 0.00000000000000000000000000000000006663 136.0
HKD2_k127_5990392_14 anti-sigma regulatory factor, serine threonine protein kinase K04757 - 2.7.11.1 0.000000000000000000000000000001943 131.0
HKD2_k127_5990392_15 - - - - 0.00000000000000000000000001971 120.0
HKD2_k127_5990392_16 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000379 108.0
HKD2_k127_5990392_17 - - - - 0.0000000000369 70.0
HKD2_k127_5990392_18 Polysaccharide deacetylase K11931 - - 0.00005598 54.0
HKD2_k127_5990392_2 ABC transporter, transmembrane region - - - 1.039e-309 970.0
HKD2_k127_5990392_3 - - - - 1.696e-256 829.0
HKD2_k127_5990392_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 402.0
HKD2_k127_5990392_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009362 408.0
HKD2_k127_5990392_6 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 419.0
HKD2_k127_5990392_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 377.0
HKD2_k127_5990392_8 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002026 266.0
HKD2_k127_5990392_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000003593 214.0
HKD2_k127_6245149_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1042.0
HKD2_k127_6245149_1 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 595.0
HKD2_k127_6245149_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 450.0
HKD2_k127_6245149_3 class II (D K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 367.0
HKD2_k127_6245149_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 372.0
HKD2_k127_6245149_5 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000002332 186.0
HKD2_k127_6245149_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000002745 180.0
HKD2_k127_6245149_7 Domain of unknown function (DUF4445) - - - 0.000000003847 60.0
HKD2_k127_629157_0 synthase K01858 - 5.5.1.4 1.387e-213 672.0
HKD2_k127_629157_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 443.0
HKD2_k127_629157_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 417.0
HKD2_k127_629157_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 402.0
HKD2_k127_629157_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 345.0
HKD2_k127_629157_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 297.0
HKD2_k127_629157_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000003411 216.0
HKD2_k127_629157_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000003655 188.0
HKD2_k127_629157_8 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000002252 176.0
HKD2_k127_629157_9 Bacterial regulatory proteins, gntR family - - - 0.00001359 48.0
HKD2_k127_636701_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 567.0
HKD2_k127_636701_1 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 547.0
HKD2_k127_636701_2 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 509.0
HKD2_k127_636701_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 483.0
HKD2_k127_636701_4 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 471.0
HKD2_k127_636701_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 428.0
HKD2_k127_636701_6 ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004157 246.0
HKD2_k127_636701_7 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001297 239.0
HKD2_k127_636701_8 PFAM inner-membrane translocator K01998 - - 0.000000000000000000000000000000000000000000009289 164.0
HKD2_k127_636701_9 Universal stress protein family - - - 0.0000000000000000000000000000000003372 135.0
HKD2_k127_6368895_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 531.0
HKD2_k127_6368895_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 457.0
HKD2_k127_6368895_10 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000001458 165.0
HKD2_k127_6368895_11 response regulator, receiver - - - 0.000000000000000000000000000000003886 143.0
HKD2_k127_6368895_13 Chemotaxis phosphatase CheX - - - 0.0000000002273 69.0
HKD2_k127_6368895_14 - - - - 0.000000001327 70.0
HKD2_k127_6368895_2 TIGRFAM flagellar hook-associated protein FlgK K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 414.0
HKD2_k127_6368895_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 379.0
HKD2_k127_6368895_4 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 355.0
HKD2_k127_6368895_5 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 331.0
HKD2_k127_6368895_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 297.0
HKD2_k127_6368895_7 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000002269 257.0
HKD2_k127_6368895_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000009903 231.0
HKD2_k127_6368895_9 Bacterial flagellin N-terminal helical region K02397 - - 0.000000000000000000000000000000000000000000000000002217 193.0
HKD2_k127_639182_0 MacB-like periplasmic core domain K02004 - - 2.819e-275 882.0
HKD2_k127_639182_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.899e-203 642.0
HKD2_k127_639182_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 317.0
HKD2_k127_639182_11 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 292.0
HKD2_k127_639182_12 HD domain K07023 - - 0.0000000000000000000000000000000000000000000000000000000000000004294 228.0
HKD2_k127_639182_13 Dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000007827 220.0
HKD2_k127_639182_14 Membrane-bound lysozyme-inhibitor of c-type lysozyme K09914 - - 0.0000000000000000000000000000000000000000002619 174.0
HKD2_k127_639182_15 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000401 153.0
HKD2_k127_639182_16 PFAM Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000002193 153.0
HKD2_k127_639182_17 - - - - 0.0000000000000000000001036 102.0
HKD2_k127_639182_18 General secretory system II protein E domain protein - - - 0.000001005 59.0
HKD2_k127_639182_2 Seven times multi-haem cytochrome CxxCH - - - 1.992e-195 650.0
HKD2_k127_639182_3 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 604.0
HKD2_k127_639182_4 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 539.0
HKD2_k127_639182_5 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 424.0
HKD2_k127_639182_6 PFAM Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 423.0
HKD2_k127_639182_7 pfam abc K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 397.0
HKD2_k127_639182_8 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 394.0
HKD2_k127_639182_9 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 318.0
HKD2_k127_6397410_0 TIGRFAM Polyketide-type polyunsaturated fatty acid synthase, PfaA - - - 0.0 1609.0
HKD2_k127_6397410_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.82e-198 631.0
HKD2_k127_6397410_10 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 299.0
HKD2_k127_6397410_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003739 238.0
HKD2_k127_6397410_12 Transcriptional regulator IclR - - - 0.000000000000000000000000000000000000000000000000000008138 199.0
HKD2_k127_6397410_13 - - - - 0.00000000000000000000000000000000000000000000007019 173.0
HKD2_k127_6397410_14 Universal stress protein - - - 0.000000000000000000000000000000000007677 141.0
HKD2_k127_6397410_15 Acetyltransferase (GNAT) domain K06977 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 - 0.00000000000000008566 81.0
HKD2_k127_6397410_16 TIGRFAM tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000001572 79.0
HKD2_k127_6397410_2 TIGRFAM PfaD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 594.0
HKD2_k127_6397410_3 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 548.0
HKD2_k127_6397410_4 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 543.0
HKD2_k127_6397410_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 383.0
HKD2_k127_6397410_6 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 359.0
HKD2_k127_6397410_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 341.0
HKD2_k127_6397410_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 310.0
HKD2_k127_6397410_9 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 315.0
HKD2_k127_6400537_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 477.0
HKD2_k127_6400537_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000306 203.0
HKD2_k127_6402206_0 TraB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 587.0
HKD2_k127_6402206_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 455.0
HKD2_k127_6402206_2 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 363.0
HKD2_k127_6402206_3 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003263 283.0
HKD2_k127_6402206_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000498 282.0
HKD2_k127_6402206_5 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000308 228.0
HKD2_k127_6402206_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000644 247.0
HKD2_k127_6402206_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000007497 178.0
HKD2_k127_6402206_8 - - - - 0.000000003289 63.0
HKD2_k127_6508752_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1317.0
HKD2_k127_6508752_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 428.0
HKD2_k127_6508752_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 415.0
HKD2_k127_6508752_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 403.0
HKD2_k127_6508752_4 DNA polymerase III, delta' K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 341.0
HKD2_k127_6508752_5 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000002402 218.0
HKD2_k127_6508752_6 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000003944 178.0
HKD2_k127_6508752_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000773 166.0
HKD2_k127_6508752_9 - - - - 0.0002123 47.0
HKD2_k127_6568743_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 589.0
HKD2_k127_6568743_1 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 487.0
HKD2_k127_6568743_10 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000009065 156.0
HKD2_k127_6568743_11 Thioesterase superfamily - - - 0.0000000000000000000003797 97.0
HKD2_k127_6568743_12 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000001523 100.0
HKD2_k127_6568743_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 450.0
HKD2_k127_6568743_3 PFAM Radical SAM superfamily K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
HKD2_k127_6568743_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008829 279.0
HKD2_k127_6568743_5 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003188 279.0
HKD2_k127_6568743_6 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000636 272.0
HKD2_k127_6568743_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 264.0
HKD2_k127_6568743_8 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000162 262.0
HKD2_k127_6568743_9 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000000000000000259 224.0
HKD2_k127_6569726_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.394e-202 636.0
HKD2_k127_6569726_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 413.0
HKD2_k127_6569726_10 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000002623 118.0
HKD2_k127_6569726_11 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000001367 118.0
HKD2_k127_6569726_2 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 412.0
HKD2_k127_6569726_3 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 316.0
HKD2_k127_6569726_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 289.0
HKD2_k127_6569726_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000007095 231.0
HKD2_k127_6569726_6 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000012 227.0
HKD2_k127_6569726_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000004606 188.0
HKD2_k127_6569726_8 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000000007149 151.0
HKD2_k127_6569726_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000001392 147.0
HKD2_k127_657592_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.135e-236 759.0
HKD2_k127_657592_1 RNA-metabolising metallo-beta-lactamase K07576 - - 7.895e-217 684.0
HKD2_k127_657592_10 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000263 186.0
HKD2_k127_657592_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000003694 169.0
HKD2_k127_657592_12 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000002042 158.0
HKD2_k127_657592_13 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000008597 143.0
HKD2_k127_657592_14 Glycosyl transferase family group 2 - - - 0.000000000000000000000000004814 122.0
HKD2_k127_657592_15 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000001516 121.0
HKD2_k127_657592_16 Single Cache domain 2 - - - 0.000000000000000000003013 109.0
HKD2_k127_657592_17 - K09143 - - 0.00000000000000002369 87.0
HKD2_k127_657592_18 Protein of unknown function (DUF3106) - - - 0.00000000000248 74.0
HKD2_k127_657592_19 Flagellar Motor Protein K02557 - - 0.00000000005568 74.0
HKD2_k127_657592_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 608.0
HKD2_k127_657592_3 PFAM iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 391.0
HKD2_k127_657592_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 376.0
HKD2_k127_657592_5 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 340.0
HKD2_k127_657592_6 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 285.0
HKD2_k127_657592_7 Radical SAM K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001246 288.0
HKD2_k127_657592_8 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000002813 221.0
HKD2_k127_657592_9 PFAM Bacterial regulatory proteins, gntR family - - - 0.0000000000000000000000000000000000000000000000008492 186.0
HKD2_k127_6600366_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 580.0
HKD2_k127_6600366_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 545.0
HKD2_k127_6600366_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 494.0
HKD2_k127_6600366_3 PFAM CBS domain containing protein K04767 - - 0.000000000000000000000000000000000000000000000000000000000004025 215.0
HKD2_k127_6640963_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1213.0
HKD2_k127_6640963_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.0 1126.0
HKD2_k127_6640963_10 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 525.0
HKD2_k127_6640963_11 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 443.0
HKD2_k127_6640963_12 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 387.0
HKD2_k127_6640963_13 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 351.0
HKD2_k127_6640963_14 TIGRFAM DNA binding domain, excisionase family K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000003432 253.0
HKD2_k127_6640963_15 Glucose inhibited division protein A K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000004718 225.0
HKD2_k127_6640963_16 PFAM Cysteine-rich - - - 0.000000000000000000000000000000000000000000000000000000000000547 214.0
HKD2_k127_6640963_17 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000004877 225.0
HKD2_k127_6640963_18 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000007834 192.0
HKD2_k127_6640963_19 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000003681 174.0
HKD2_k127_6640963_2 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1049.0
HKD2_k127_6640963_20 Lytic transglycosylase - - - 0.00000000000000000000000000000000000000005077 162.0
HKD2_k127_6640963_21 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000006991 115.0
HKD2_k127_6640963_22 YsiA-like protein, C-terminal region - - - 0.00000000000000000000000002831 116.0
HKD2_k127_6640963_24 Belongs to the UPF0758 family K03630 - - 0.000000000001682 68.0
HKD2_k127_6640963_25 - - - - 0.00000000003579 66.0
HKD2_k127_6640963_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.243e-237 741.0
HKD2_k127_6640963_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.592e-229 719.0
HKD2_k127_6640963_5 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 5.368e-225 713.0
HKD2_k127_6640963_6 Belongs to the thiolase family K00626 - 2.3.1.9 3.099e-206 649.0
HKD2_k127_6640963_7 Domain in cystathionine beta-synthase and other proteins. K07182 - - 3.53e-206 659.0
HKD2_k127_6640963_8 PFAM MgsA AAA ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 592.0
HKD2_k127_6640963_9 PFAM aminotransferase class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 533.0
HKD2_k127_6660233_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1027.0
HKD2_k127_6660233_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 527.0
HKD2_k127_6660233_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001892 285.0
HKD2_k127_6688167_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1214.0
HKD2_k127_6688167_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 6.511e-195 618.0
HKD2_k127_6688167_10 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008751 327.0
HKD2_k127_6688167_12 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000001959 221.0
HKD2_k127_6688167_13 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000000000000002286 242.0
HKD2_k127_6688167_14 PFAM aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000003126 217.0
HKD2_k127_6688167_15 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000000000000000000000000000000000002849 184.0
HKD2_k127_6688167_16 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000004286 147.0
HKD2_k127_6688167_17 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000231 122.0
HKD2_k127_6688167_18 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000001751 109.0
HKD2_k127_6688167_19 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000000000002848 90.0
HKD2_k127_6688167_2 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 597.0
HKD2_k127_6688167_20 - - - - 0.00002681 51.0
HKD2_k127_6688167_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 537.0
HKD2_k127_6688167_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 504.0
HKD2_k127_6688167_5 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 493.0
HKD2_k127_6688167_6 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
HKD2_k127_6688167_7 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 374.0
HKD2_k127_6688167_8 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 329.0
HKD2_k127_6688167_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 326.0
HKD2_k127_6721888_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 442.0
HKD2_k127_6721888_1 chlorophyll binding K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 454.0
HKD2_k127_6721888_10 - - - - 0.00000000001327 76.0
HKD2_k127_6721888_2 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 362.0
HKD2_k127_6721888_3 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 361.0
HKD2_k127_6721888_4 PFAM Bile acid sodium symporter K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004068 263.0
HKD2_k127_6721888_5 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003159 261.0
HKD2_k127_6721888_6 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000431 176.0
HKD2_k127_6721888_7 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000193 155.0
HKD2_k127_6721888_8 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000004207 143.0
HKD2_k127_6721888_9 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.00000000000000000006847 104.0
HKD2_k127_6733661_0 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 473.0
HKD2_k127_6733661_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 395.0
HKD2_k127_6733661_2 HIT domain - - - 0.00000000000000000000000000000000000000056 151.0
HKD2_k127_6733661_3 COG0477 Permeases of the major facilitator superfamily K08151 - - 0.0002231 53.0
HKD2_k127_6797969_0 thiamine transport K02011 - - 2.568e-258 807.0
HKD2_k127_6797969_1 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 543.0
HKD2_k127_6797969_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 376.0
HKD2_k127_6797969_3 D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit K16371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 327.0
HKD2_k127_6797969_4 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000001091 181.0
HKD2_k127_6797969_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000006133 188.0
HKD2_k127_6797969_6 enoyl-CoA hydratase K01715 - 4.2.1.17 0.00000000000000000000000000000000004194 156.0
HKD2_k127_6805317_0 chelatase, subunit ChlI K07391 - - 1.6e-238 747.0
HKD2_k127_6805317_1 amidinotransferase K00613 - 2.1.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 482.0
HKD2_k127_6805317_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000002819 233.0
HKD2_k127_6805317_11 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000002964 210.0
HKD2_k127_6805317_12 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000001353 216.0
HKD2_k127_6805317_13 PFAM conserved K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000007281 186.0
HKD2_k127_6805317_14 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000004442 185.0
HKD2_k127_6805317_15 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000001991 173.0
HKD2_k127_6805317_16 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000006912 138.0
HKD2_k127_6805317_17 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000004646 147.0
HKD2_k127_6805317_18 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000002491 125.0
HKD2_k127_6805317_19 - - - - 0.0000000000000000008664 90.0
HKD2_k127_6805317_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 430.0
HKD2_k127_6805317_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00000000000000001805 89.0
HKD2_k127_6805317_21 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000000168 71.0
HKD2_k127_6805317_22 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs - - - 0.00000003873 55.0
HKD2_k127_6805317_3 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 411.0
HKD2_k127_6805317_4 PFAM MltA K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 400.0
HKD2_k127_6805317_5 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 379.0
HKD2_k127_6805317_6 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 313.0
HKD2_k127_6805317_7 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001085 289.0
HKD2_k127_6805317_8 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004109 271.0
HKD2_k127_6808242_0 Conserved carboxylase domain K01571,K01960,K03416 - 2.1.3.1,4.1.1.3,6.4.1.1 0.0 1015.0
HKD2_k127_6808242_1 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.577e-281 870.0
HKD2_k127_6808242_2 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847 - 5.4.99.2 7.497e-208 653.0
HKD2_k127_6808242_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 587.0
HKD2_k127_6808242_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 490.0
HKD2_k127_6808242_5 LAO AO transport system K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 440.0
HKD2_k127_6808242_6 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 350.0
HKD2_k127_6808242_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000001701 154.0
HKD2_k127_6808242_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000001026 95.0
HKD2_k127_681742_0 Arylsulfotransferase (ASST) - - - 3.988e-251 780.0
HKD2_k127_681742_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.681e-216 681.0
HKD2_k127_681742_2 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 491.0
HKD2_k127_681742_3 Belongs to the ArsC family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000006004 229.0
HKD2_k127_681742_4 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000009997 138.0
HKD2_k127_6833198_0 PFAM Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 514.0
HKD2_k127_6833198_1 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 470.0
HKD2_k127_6833198_2 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 454.0
HKD2_k127_6833198_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 392.0
HKD2_k127_6833198_4 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 314.0
HKD2_k127_6833198_5 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000003253 213.0
HKD2_k127_6833198_6 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.0000000000000000000000000000000000000000000000000005031 194.0
HKD2_k127_6833198_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000003117 109.0
HKD2_k127_6833198_8 cytochrome c K00405,K07245 - - 0.0000000000000000000000007823 108.0
HKD2_k127_6867880_0 malic protein domain protein K00029 - 1.1.1.40 0.0 1060.0
HKD2_k127_6867880_1 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 306.0
HKD2_k127_6867880_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 320.0
HKD2_k127_6867880_3 YtkA-like - - - 0.00000000344 65.0
HKD2_k127_6904678_0 pyruvate phosphate dikinase - - - 0.0 1107.0
HKD2_k127_6904678_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.023e-262 826.0
HKD2_k127_6904678_10 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000219 155.0
HKD2_k127_6904678_11 TPR repeat - - - 0.0000000000000000000000000000000003091 137.0
HKD2_k127_6904678_12 - - - - 0.0000000000000000000000000000000004468 137.0
HKD2_k127_6904678_13 - - - - 0.000000007151 67.0
HKD2_k127_6904678_14 - - - - 0.00002569 47.0
HKD2_k127_6904678_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0007057 48.0
HKD2_k127_6904678_2 heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 389.0
HKD2_k127_6904678_3 PFAM Radical SAM domain protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 364.0
HKD2_k127_6904678_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 332.0
HKD2_k127_6904678_5 Domain of unknown function (DUF1848) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 310.0
HKD2_k127_6904678_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000001226 217.0
HKD2_k127_6904678_7 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000004164 216.0
HKD2_k127_6904678_8 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000001259 153.0
HKD2_k127_6904678_9 phosphorelay sensor kinase activity K03407 - 2.7.13.3 0.000000000000000000000000000000000000006162 167.0
HKD2_k127_6907093_0 anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1140.0
HKD2_k127_6907093_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.134e-270 843.0
HKD2_k127_6907093_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 294.0
HKD2_k127_6907093_3 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
HKD2_k127_6907093_4 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000007676 232.0
HKD2_k127_6907093_5 - - - - 0.00000000000000000000000000185 119.0
HKD2_k127_6907093_6 Protein of unknown function, DUF255 - - - 0.00000000000000000000000001893 111.0
HKD2_k127_6966235_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.045e-269 842.0
HKD2_k127_6966235_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 408.0
HKD2_k127_6966235_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 398.0
HKD2_k127_6966235_3 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00020,K19647 - 1.1.1.291,1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 400.0
HKD2_k127_6966235_4 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 379.0
HKD2_k127_6966235_5 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 353.0
HKD2_k127_6966235_6 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000006329 73.0
HKD2_k127_6966235_7 Mut7-C ubiquitin K03154 - - 0.00001897 49.0
HKD2_k127_699282_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 1.331e-222 702.0
HKD2_k127_699282_1 Binding-protein-dependent transport system inner membrane component K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 448.0
HKD2_k127_699282_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 421.0
HKD2_k127_699282_3 Binding-protein-dependent transport system inner membrane component K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 368.0
HKD2_k127_699282_4 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 361.0
HKD2_k127_699282_5 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004544 261.0
HKD2_k127_699282_6 Putative citrate transport - - - 0.000000001353 59.0
HKD2_k127_7017694_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.123e-198 623.0
HKD2_k127_7017694_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 440.0
HKD2_k127_7017694_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 355.0
HKD2_k127_7017694_3 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003343 310.0
HKD2_k127_7017694_4 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005564 249.0
HKD2_k127_7017694_5 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000004758 185.0
HKD2_k127_7064545_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1261.0
HKD2_k127_7064545_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 1.104e-311 977.0
HKD2_k127_7064545_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 394.0
HKD2_k127_7064545_11 PFAM phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 390.0
HKD2_k127_7064545_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 368.0
HKD2_k127_7064545_13 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 367.0
HKD2_k127_7064545_14 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 362.0
HKD2_k127_7064545_15 Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 338.0
HKD2_k127_7064545_16 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 338.0
HKD2_k127_7064545_17 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 309.0
HKD2_k127_7064545_18 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 310.0
HKD2_k127_7064545_19 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 307.0
HKD2_k127_7064545_2 4Fe-4S dicluster domain - - - 7.813e-307 945.0
HKD2_k127_7064545_20 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001522 278.0
HKD2_k127_7064545_21 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001938 249.0
HKD2_k127_7064545_22 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000003057 244.0
HKD2_k127_7064545_23 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000001618 235.0
HKD2_k127_7064545_24 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000002114 232.0
HKD2_k127_7064545_25 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000002281 235.0
HKD2_k127_7064545_26 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000003194 226.0
HKD2_k127_7064545_27 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000002382 220.0
HKD2_k127_7064545_28 - - - - 0.000000000000000000000000000000000000000000000000000009552 192.0
HKD2_k127_7064545_29 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000001766 194.0
HKD2_k127_7064545_3 PFAM Polysulphide reductase, NrfD K00185 - - 4.484e-196 616.0
HKD2_k127_7064545_30 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000003513 188.0
HKD2_k127_7064545_31 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000005666 186.0
HKD2_k127_7064545_32 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000001548 190.0
HKD2_k127_7064545_33 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000007635 139.0
HKD2_k127_7064545_4 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 584.0
HKD2_k127_7064545_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 556.0
HKD2_k127_7064545_6 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 556.0
HKD2_k127_7064545_7 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 474.0
HKD2_k127_7064545_8 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 467.0
HKD2_k127_7064545_9 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 432.0
HKD2_k127_7120385_0 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 378.0
HKD2_k127_7120385_1 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002923 278.0
HKD2_k127_7120385_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000003804 228.0
HKD2_k127_7120385_3 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000001525 167.0
HKD2_k127_7120385_4 - - - - 0.0000000004175 64.0
HKD2_k127_7120385_5 - - - - 0.000000294 55.0
HKD2_k127_7134611_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1332.0
HKD2_k127_7134611_1 metal-dependent hydrolase with the TIM-barrel fold - - - 1.003e-243 758.0
HKD2_k127_7134611_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 358.0
HKD2_k127_7134611_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 340.0
HKD2_k127_7134611_12 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 302.0
HKD2_k127_7134611_13 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001816 258.0
HKD2_k127_7134611_14 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004829 243.0
HKD2_k127_7134611_15 UbiC transcription regulator-associated K03710 - - 0.00000000000000000000000000000000000000000000003122 180.0
HKD2_k127_7134611_16 acyl-CoA synthetase - - - 0.0000000000000000000000000000000000000000000005985 186.0
HKD2_k127_7134611_17 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000212 166.0
HKD2_k127_7134611_18 aminoacyl-tRNA metabolism involved in translational fidelity K19055 - - 0.00000000000000000000000000000004814 130.0
HKD2_k127_7134611_19 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000008651 125.0
HKD2_k127_7134611_2 TRAP transporter, 4TM 12TM fusion protein - - - 1.502e-227 720.0
HKD2_k127_7134611_3 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 495.0
HKD2_k127_7134611_4 sarcosine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 496.0
HKD2_k127_7134611_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 490.0
HKD2_k127_7134611_6 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 460.0
HKD2_k127_7134611_7 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 427.0
HKD2_k127_7134611_8 TRAP transporter solute receptor, TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 425.0
HKD2_k127_7134611_9 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 386.0
HKD2_k127_7238842_0 Pyruvate phosphate dikinase, PEP K01006 - 2.7.9.1 0.0 1476.0
HKD2_k127_7238842_1 Peptidase M16C associated K06972 - - 0.0 1132.0
HKD2_k127_7238842_10 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003937 286.0
HKD2_k127_7238842_11 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000000000000000003101 208.0
HKD2_k127_7238842_12 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.000000000000000000000000000000000000000000001619 165.0
HKD2_k127_7238842_13 PFAM Rhodanese domain protein - - - 0.0000000000000000000000002071 113.0
HKD2_k127_7238842_14 - - - - 0.00000000000000000000005019 104.0
HKD2_k127_7238842_15 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000002164 95.0
HKD2_k127_7238842_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.944e-297 919.0
HKD2_k127_7238842_3 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 6.686e-226 708.0
HKD2_k127_7238842_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 587.0
HKD2_k127_7238842_5 TIGRFAM histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 566.0
HKD2_k127_7238842_6 PFAM dihydropteroate synthase DHPS K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 498.0
HKD2_k127_7238842_7 PFAM Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 432.0
HKD2_k127_7238842_8 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 381.0
HKD2_k127_7238842_9 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 339.0
HKD2_k127_7252377_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 560.0
HKD2_k127_7252377_1 Domain of unknown function (DUF4198) K02009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 359.0
HKD2_k127_7252377_10 Large extracellular alpha-helical protein K16915 - - 0.00000000001255 69.0
HKD2_k127_7252377_11 Sporulation related domain - - - 0.00000000002792 73.0
HKD2_k127_7252377_13 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000001246 53.0
HKD2_k127_7252377_2 PFAM ABC transporter K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 307.0
HKD2_k127_7252377_3 PFAM Carbohydrate-selective porin OprB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 317.0
HKD2_k127_7252377_4 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006332 254.0
HKD2_k127_7252377_5 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000005991 216.0
HKD2_k127_7252377_6 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000001108 191.0
HKD2_k127_7252377_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000008181 125.0
HKD2_k127_7252377_8 Large extracellular alpha-helical protein K16915 - - 0.00000000000000000000104 106.0
HKD2_k127_7252377_9 RNA-binding protein - - - 0.0000000000004664 78.0
HKD2_k127_7261554_0 transporter, DctM subunit K11690 - - 8.993e-195 623.0
HKD2_k127_7261554_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 545.0
HKD2_k127_7261554_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 481.0
HKD2_k127_7261554_3 NAD(P)H binding domain of trans-2-enoyl-CoA reductase K00209 - 1.3.1.44,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 459.0
HKD2_k127_7261554_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 267.0
HKD2_k127_7261554_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000001877 225.0
HKD2_k127_7261554_6 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000001493 117.0
HKD2_k127_7263761_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430,K05306 - 2.6.1.37,3.11.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 486.0
HKD2_k127_7263761_1 TIGRFAM TRAP transporter, DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 425.0
HKD2_k127_7263761_2 Aldehyde dehydrogenase family K15515,K18119 - 1.2.1.76,1.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 384.0
HKD2_k127_7263761_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 298.0
HKD2_k127_7263761_4 Citrate synthase K01647 - 2.3.3.1 0.00000000000000000685 98.0
HKD2_k127_7263761_5 hydrolase (HAD superfamily) K01560,K07025 - 3.8.1.2 0.000000000000009594 83.0
HKD2_k127_7263761_6 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000001506 63.0
HKD2_k127_7300612_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 492.0
HKD2_k127_7300612_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 314.0
HKD2_k127_7300612_2 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001286 284.0
HKD2_k127_7436571_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 1.778e-201 670.0
HKD2_k127_7436571_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 396.0
HKD2_k127_7436571_2 PFAM RimK domain protein ATP-grasp K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 302.0
HKD2_k127_7436571_3 PFAM HNH endonuclease K07451 - - 0.000000000000000000000000000000000000001646 149.0
HKD2_k127_7439889_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 418.0
HKD2_k127_7439889_1 Class ii aldolase K01628,K18847 - 2.2.1.8,4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 343.0
HKD2_k127_7439889_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 327.0
HKD2_k127_7439889_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004183 281.0
HKD2_k127_7439889_4 Alpha/beta hydrolase family K01175 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
HKD2_k127_751194_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 481.0
HKD2_k127_751194_1 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 357.0
HKD2_k127_751194_2 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 351.0
HKD2_k127_751194_3 electron transfer flavoprotein K22431 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000002741 243.0
HKD2_k127_751194_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000001358 177.0
HKD2_k127_751194_5 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000001085 113.0
HKD2_k127_751194_6 DinB family - - - 0.00000000000004976 74.0
HKD2_k127_7544515_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 2.073e-221 697.0
HKD2_k127_7544515_1 Cation transport protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 407.0
HKD2_k127_7544515_10 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000003224 196.0
HKD2_k127_7544515_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000007694 192.0
HKD2_k127_7544515_12 cobalamin binding K01849,K11942 - 5.4.99.13,5.4.99.2 0.000000000000000000000000000000000000000187 155.0
HKD2_k127_7544515_2 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 399.0
HKD2_k127_7544515_3 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 364.0
HKD2_k127_7544515_4 PFAM chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 380.0
HKD2_k127_7544515_5 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001225 285.0
HKD2_k127_7544515_6 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006414 282.0
HKD2_k127_7544515_7 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
HKD2_k127_7544515_8 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000001611 223.0
HKD2_k127_7544515_9 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000001304 201.0
HKD2_k127_7673989_0 AAA-like domain - - - 1.156e-258 818.0
HKD2_k127_7673989_1 Cytochrome c554 and c-prime - - - 4.502e-245 778.0
HKD2_k127_7673989_10 PFAM Rieske 2Fe-2S domain K02636 - 1.10.9.1 0.00004802 47.0
HKD2_k127_7673989_2 Tripartite tricarboxylate transporter TctA family - - - 3.859e-212 670.0
HKD2_k127_7673989_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 395.0
HKD2_k127_7673989_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 342.0
HKD2_k127_7673989_5 HpcH/HpaI aldolase/citrate lyase family K02510,K12660 - 4.1.2.52,4.1.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000153 302.0
HKD2_k127_7673989_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000386 251.0
HKD2_k127_7673989_7 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000004311 119.0
HKD2_k127_7673989_8 - - - - 0.0000000000000000000003926 104.0
HKD2_k127_7673989_9 Tripartite tricarboxylate transporter TctB family - - - 0.000000000004267 73.0
HKD2_k127_7679039_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1104.0
HKD2_k127_7679039_1 PFAM Acetyl-CoA hydrolase transferase - - - 2.824e-289 902.0
HKD2_k127_7679039_2 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001304 246.0
HKD2_k127_7679039_3 Smr domain - - - 0.00000000000000000000000000000000000000000000000001369 188.0
HKD2_k127_7679039_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000001428 114.0
HKD2_k127_7683105_0 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 503.0
HKD2_k127_7683105_1 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000009186 198.0
HKD2_k127_7683105_2 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000006769 59.0
HKD2_k127_7683707_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.908e-291 909.0
HKD2_k127_7683707_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 608.0
HKD2_k127_7683707_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 429.0
HKD2_k127_7683707_3 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 426.0
HKD2_k127_7683707_4 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 353.0
HKD2_k127_7683707_5 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 328.0
HKD2_k127_7683707_6 YacP-like NYN domain K06962 - - 0.0000000000000000000000000000000000001164 147.0
HKD2_k127_7683707_7 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000004081 78.0
HKD2_k127_7690819_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 597.0
HKD2_k127_7690819_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 356.0
HKD2_k127_7694334_0 Pyruvate phosphate dikinase PEP K01007 - 2.7.9.2 1.233e-293 925.0
HKD2_k127_7694334_1 AMP-binding enzyme K00666 - - 5.799e-224 708.0
HKD2_k127_7694334_10 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 451.0
HKD2_k127_7694334_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 397.0
HKD2_k127_7694334_12 Cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 369.0
HKD2_k127_7694334_13 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 359.0
HKD2_k127_7694334_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 323.0
HKD2_k127_7694334_15 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 325.0
HKD2_k127_7694334_16 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 313.0
HKD2_k127_7694334_17 lipid kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 314.0
HKD2_k127_7694334_18 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 300.0
HKD2_k127_7694334_19 ThiF family K03148 - 2.7.7.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002587 286.0
HKD2_k127_7694334_2 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 1.823e-203 645.0
HKD2_k127_7694334_20 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003445 281.0
HKD2_k127_7694334_21 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006867 273.0
HKD2_k127_7694334_22 Permease, YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001486 274.0
HKD2_k127_7694334_23 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003954 261.0
HKD2_k127_7694334_24 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004466 239.0
HKD2_k127_7694334_25 WxcM-like, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000005962 214.0
HKD2_k127_7694334_26 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000006225 180.0
HKD2_k127_7694334_27 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000007567 149.0
HKD2_k127_7694334_28 Glycosyl transferase, family 2 K07011 - - 0.0000000000000000000000000000000002293 150.0
HKD2_k127_7694334_29 - - - - 0.000000000000000000000000001112 123.0
HKD2_k127_7694334_3 ABC transporter K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 584.0
HKD2_k127_7694334_30 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K14661 - - 0.0000000000000000001938 95.0
HKD2_k127_7694334_31 PilZ domain - - - 0.0002728 52.0
HKD2_k127_7694334_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 559.0
HKD2_k127_7694334_5 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 505.0
HKD2_k127_7694334_6 synthase K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 491.0
HKD2_k127_7694334_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 493.0
HKD2_k127_7694334_8 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 493.0
HKD2_k127_7694334_9 carbohydrate transport K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 451.0
HKD2_k127_7698628_0 Amidohydrolase family - - - 4.204e-194 618.0
HKD2_k127_7698628_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 345.0
HKD2_k127_7698628_2 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 323.0
HKD2_k127_7698628_3 Putative bacterial lipoprotein (DUF799) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 297.0
HKD2_k127_7698628_4 YdjC-like protein - - - 0.00000000000000000000000000000000000000000000000000000001442 210.0
HKD2_k127_7698628_5 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000335 150.0
HKD2_k127_7698628_6 TIGRFAM endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000009025 151.0
HKD2_k127_7698628_7 integral membrane protein - - - 0.00000000000000000000000000002618 132.0
HKD2_k127_7698628_8 Methyltransferase domain - - - 0.0000000000000000000000007211 113.0
HKD2_k127_7698628_9 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000441 116.0
HKD2_k127_7708874_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 450.0
HKD2_k127_7708874_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000373 239.0
HKD2_k127_7708874_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000001064 236.0
HKD2_k127_7708874_3 Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000006198 221.0
HKD2_k127_7708874_4 Domain of unknown function (DUF309) - - - 0.00000000000000000000000000000002512 133.0
HKD2_k127_7715919_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 1.762e-301 931.0
HKD2_k127_7715919_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 6.574e-277 861.0
HKD2_k127_7715919_2 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 607.0
HKD2_k127_7715919_3 TOBE domain K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 497.0
HKD2_k127_7715919_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000004826 184.0
HKD2_k127_7715919_5 PFAM Cold-shock K03704 - - 0.00000000000000000000000000009337 116.0
HKD2_k127_7749307_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.767e-303 957.0
HKD2_k127_7749307_1 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 1.421e-296 937.0
HKD2_k127_7749307_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.14e-293 926.0
HKD2_k127_7749307_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.459e-241 750.0
HKD2_k127_7749307_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 487.0
HKD2_k127_7749307_5 L-glutamate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 431.0
HKD2_k127_7749307_6 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000008921 188.0
HKD2_k127_7749307_7 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000006692 115.0
HKD2_k127_7750252_0 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 400.0
HKD2_k127_7750252_1 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000002181 224.0
HKD2_k127_7750252_2 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000006692 159.0
HKD2_k127_7750252_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000002098 131.0
HKD2_k127_7750252_4 50S ribosome-binding GTPase - - - 0.000000000006197 79.0
HKD2_k127_7750252_5 Tetratricopeptide repeat K09527 GO:0003002,GO:0006950,GO:0006970,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0008150,GO:0009628,GO:0009719,GO:0009725,GO:0009733,GO:0009734,GO:0009741,GO:0009742,GO:0009755,GO:0009987,GO:0010033,GO:0010051,GO:0010305,GO:0014070,GO:0023052,GO:0032501,GO:0032502,GO:0032870,GO:0033993,GO:0042221,GO:0043401,GO:0048545,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071310,GO:0071365,GO:0071367,GO:0071383,GO:0071396,GO:0071407,GO:0071495,GO:1901700,GO:1901701 - 0.0000006629 63.0
HKD2_k127_7752692_0 Bifunctional protein K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 558.0
HKD2_k127_7752692_1 PFAM homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 531.0
HKD2_k127_7752692_2 phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000209 281.0
HKD2_k127_7752692_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000003013 156.0
HKD2_k127_7752692_4 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000004741 98.0
HKD2_k127_7752692_5 - - - - 0.0000000002462 61.0
HKD2_k127_7752692_6 Phage integrase SAM-like domain - - - 0.0005555 44.0
HKD2_k127_7761710_0 TIGRFAM threonine synthase K01733 - 4.2.3.1 6.714e-236 759.0
HKD2_k127_7761710_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.102e-194 614.0
HKD2_k127_7761710_2 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000003611 239.0
HKD2_k127_7761710_3 PFAM TrkA-N domain K10716 - - 0.00000000000000000003369 91.0
HKD2_k127_7771919_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1951.0
HKD2_k127_7771919_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.084e-253 814.0
HKD2_k127_7771919_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 317.0
HKD2_k127_7771919_3 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 266.0
HKD2_k127_7771919_4 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000001662 234.0
HKD2_k127_7782881_0 extracellular solute-binding protein, family 5 - - - 1.324e-236 740.0
HKD2_k127_7782881_1 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 467.0
HKD2_k127_7782881_2 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 451.0
HKD2_k127_7782881_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 439.0
HKD2_k127_7782881_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000001441 117.0
HKD2_k127_7808856_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 591.0
HKD2_k127_7808856_1 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 338.0
HKD2_k127_7808856_2 PFAM Rieske 2Fe-2S iron-sulphur domain K03886 - - 0.000000000000000000000000003094 117.0
HKD2_k127_7816043_0 Elongation factor Tu domain 2 K02355 - - 1.949e-314 976.0
HKD2_k127_7816043_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.125e-286 902.0
HKD2_k127_7816043_10 radical SAM domain protein K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 473.0
HKD2_k127_7816043_11 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 467.0
HKD2_k127_7816043_12 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 447.0
HKD2_k127_7816043_13 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 435.0
HKD2_k127_7816043_14 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 428.0
HKD2_k127_7816043_15 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 431.0
HKD2_k127_7816043_16 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 427.0
HKD2_k127_7816043_17 ABC transporter, permease protein K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 414.0
HKD2_k127_7816043_18 Phosphomannose isomerase type I K01809,K01840 - 5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 347.0
HKD2_k127_7816043_19 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 329.0
HKD2_k127_7816043_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.517e-279 871.0
HKD2_k127_7816043_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008306 341.0
HKD2_k127_7816043_21 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 329.0
HKD2_k127_7816043_22 Belongs to the BI1 family K06890,K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 319.0
HKD2_k127_7816043_23 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 312.0
HKD2_k127_7816043_24 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 293.0
HKD2_k127_7816043_25 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 293.0
HKD2_k127_7816043_26 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000331 291.0
HKD2_k127_7816043_27 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005278 303.0
HKD2_k127_7816043_28 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
HKD2_k127_7816043_29 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009669 247.0
HKD2_k127_7816043_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.363e-256 836.0
HKD2_k127_7816043_30 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000001584 235.0
HKD2_k127_7816043_31 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000001761 227.0
HKD2_k127_7816043_32 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000001383 200.0
HKD2_k127_7816043_33 Nuclease (SNase domain protein) - - - 0.00000000000000000000000000000000000000000000001725 178.0
HKD2_k127_7816043_34 ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000008161 166.0
HKD2_k127_7816043_36 - - - - 0.00000000000000000000000000000000338 132.0
HKD2_k127_7816043_37 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000009712 135.0
HKD2_k127_7816043_38 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000001199 127.0
HKD2_k127_7816043_39 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000002715 132.0
HKD2_k127_7816043_4 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 3.17e-250 810.0
HKD2_k127_7816043_40 PilZ domain - - - 0.0000000000000000000000005858 108.0
HKD2_k127_7816043_41 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000001475 94.0
HKD2_k127_7816043_42 - - - - 0.00000000000000000001535 94.0
HKD2_k127_7816043_43 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.00000000000000000005472 105.0
HKD2_k127_7816043_44 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000003852 86.0
HKD2_k127_7816043_45 - - - - 0.0000000000000005647 87.0
HKD2_k127_7816043_46 OstA-like protein K09774 - - 0.0000000004067 69.0
HKD2_k127_7816043_49 - - - - 0.0000441 51.0
HKD2_k127_7816043_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.676e-249 780.0
HKD2_k127_7816043_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 625.0
HKD2_k127_7816043_7 Nucleoside recognition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 567.0
HKD2_k127_7816043_8 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 548.0
HKD2_k127_7816043_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 499.0
HKD2_k127_7824562_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.036e-302 966.0
HKD2_k127_7824562_1 glycyl-tRNA synthetase, beta K01879 - 6.1.1.14 5.149e-216 705.0
HKD2_k127_7824562_10 - - - - 0.00000000000000000000000000000000005871 135.0
HKD2_k127_7824562_11 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000003862 131.0
HKD2_k127_7824562_12 Unextendable partial coding region - - - 0.0000000000000004111 79.0
HKD2_k127_7824562_2 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 524.0
HKD2_k127_7824562_3 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 497.0
HKD2_k127_7824562_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 358.0
HKD2_k127_7824562_5 PFAM GHMP kinase K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 344.0
HKD2_k127_7824562_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006797 246.0
HKD2_k127_7824562_7 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000005572 217.0
HKD2_k127_7824562_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000009088 150.0
HKD2_k127_7824562_9 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000057 153.0
HKD2_k127_788922_0 PFAM type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 394.0
HKD2_k127_788922_1 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 304.0
HKD2_k127_788922_2 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 286.0
HKD2_k127_788922_3 - - - - 0.000000000001296 74.0
HKD2_k127_788922_4 - - - - 0.000000000006266 76.0
HKD2_k127_7949381_0 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K07444,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 438.0
HKD2_k127_7949381_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000001281 213.0
HKD2_k127_7949381_2 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000002194 203.0
HKD2_k127_7949381_3 - - - - 0.0000000000000000001824 93.0
HKD2_k127_7949381_4 - - - - 0.000000000000000004067 91.0
HKD2_k127_7949381_5 PIN domain - - - 0.0000000000001162 72.0
HKD2_k127_7949381_6 - - - - 0.00005446 55.0
HKD2_k127_7949381_7 Tripartite tricarboxylate transporter family receptor - - - 0.0003365 45.0
HKD2_k127_7953129_0 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 0.0 1184.0
HKD2_k127_7953129_1 PFAM response regulator receiver K02481,K07712 - - 1.027e-217 685.0
HKD2_k127_7953129_10 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000001828 143.0
HKD2_k127_7953129_11 cheY-homologous receiver domain K07658 - - 0.00000000000000000949 94.0
HKD2_k127_7953129_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.399e-216 678.0
HKD2_k127_7953129_3 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 327.0
HKD2_k127_7953129_4 PFAM CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 280.0
HKD2_k127_7953129_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000004514 230.0
HKD2_k127_7953129_6 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000192 181.0
HKD2_k127_7953129_7 Universal stress protein family K06149 - - 0.0000000000000000000000000000000000000000001995 169.0
HKD2_k127_7953129_8 formate dehydrogenase (NAD+) activity K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000003663 163.0
HKD2_k127_7953129_9 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000001969 135.0
HKD2_k127_7953836_0 type IV pilus assembly PilZ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 592.0
HKD2_k127_7953836_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 281.0
HKD2_k127_8004518_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1347.0
HKD2_k127_8004518_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1076.0
HKD2_k127_8004518_10 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 419.0
HKD2_k127_8004518_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 387.0
HKD2_k127_8004518_12 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 362.0
HKD2_k127_8004518_13 NIL - - - 0.000000000000000000000000000000000000000000000000000000000000003048 220.0
HKD2_k127_8004518_14 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000001471 190.0
HKD2_k127_8004518_15 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000001019 160.0
HKD2_k127_8004518_16 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000002257 132.0
HKD2_k127_8004518_17 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000005066 132.0
HKD2_k127_8004518_18 - - - - 0.000002034 58.0
HKD2_k127_8004518_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 2.882e-257 805.0
HKD2_k127_8004518_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.038e-256 797.0
HKD2_k127_8004518_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.998e-231 728.0
HKD2_k127_8004518_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 4.695e-209 662.0
HKD2_k127_8004518_6 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 4.092e-203 642.0
HKD2_k127_8004518_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 595.0
HKD2_k127_8004518_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 567.0
HKD2_k127_8004518_9 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 425.0
HKD2_k127_804550_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 499.0
HKD2_k127_804550_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 419.0
HKD2_k127_804550_10 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000000001161 84.0
HKD2_k127_804550_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 388.0
HKD2_k127_804550_3 ABC transporter K02028,K09972,K10004,K10038 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 362.0
HKD2_k127_804550_4 Belongs to the bacterial solute-binding protein 3 family K02030,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 301.0
HKD2_k127_804550_5 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 296.0
HKD2_k127_804550_6 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K10003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008442 244.0
HKD2_k127_804550_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000002713 237.0
HKD2_k127_804550_8 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.000000000000000000000000000000000000000000000000000000000001223 219.0
HKD2_k127_804550_9 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000001194 204.0
HKD2_k127_8055730_0 BadF BadG BcrA BcrD - - - 0.0 1108.0
HKD2_k127_8055730_1 PFAM ribonuclease II K01147,K12573 - 3.1.13.1 3.115e-224 713.0
HKD2_k127_8055730_2 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 475.0
HKD2_k127_8055730_3 AIR synthase related protein, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 444.0
HKD2_k127_8055730_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 309.0
HKD2_k127_8055730_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000009749 209.0
HKD2_k127_8055730_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000003056 207.0
HKD2_k127_8055730_7 Aminoacyl-tRNA editing domain K01284 - 3.4.15.5 0.00000000000000000000000000000000000000000000000000002034 192.0
HKD2_k127_8055730_8 ABC transporter transmembrane region K06147,K18889 - - 0.0000000005452 62.0
HKD2_k127_8064190_0 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 1.114e-211 689.0
HKD2_k127_8064190_1 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 1.223e-202 659.0
HKD2_k127_8064190_10 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 390.0
HKD2_k127_8064190_11 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 385.0
HKD2_k127_8064190_12 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 385.0
HKD2_k127_8064190_13 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 362.0
HKD2_k127_8064190_14 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 361.0
HKD2_k127_8064190_15 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000003384 284.0
HKD2_k127_8064190_16 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001134 271.0
HKD2_k127_8064190_17 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001569 253.0
HKD2_k127_8064190_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004959 258.0
HKD2_k127_8064190_19 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000153 250.0
HKD2_k127_8064190_2 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 559.0
HKD2_k127_8064190_20 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000009092 244.0
HKD2_k127_8064190_21 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000001675 177.0
HKD2_k127_8064190_22 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000006129 148.0
HKD2_k127_8064190_23 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000003371 145.0
HKD2_k127_8064190_24 regulatory protein, FmdB family - - - 0.00000000000000000000000008463 111.0
HKD2_k127_8064190_25 transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000002342 106.0
HKD2_k127_8064190_26 DnaJ molecular chaperone homology domain - - - 0.0000000000000000001179 91.0
HKD2_k127_8064190_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 549.0
HKD2_k127_8064190_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 528.0
HKD2_k127_8064190_5 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 514.0
HKD2_k127_8064190_6 PFAM aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 510.0
HKD2_k127_8064190_7 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 511.0
HKD2_k127_8064190_8 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 476.0
HKD2_k127_8064190_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 399.0
HKD2_k127_8084186_0 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 600.0
HKD2_k127_8084186_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 441.0
HKD2_k127_8084186_2 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 427.0
HKD2_k127_8084186_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 284.0
HKD2_k127_8109865_0 BadF BadG BcrA BcrD - - - 4.763e-199 655.0
HKD2_k127_8109865_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 602.0
HKD2_k127_8109865_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 511.0
HKD2_k127_8109865_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 492.0
HKD2_k127_8109865_4 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 400.0
HKD2_k127_8109865_5 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 329.0
HKD2_k127_8109865_6 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K04488,K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002606 280.0
HKD2_k127_8109865_7 Rhodanese Homology Domain K01069 - 3.1.2.6 0.00000000000000000000000000000000000000004006 172.0
HKD2_k127_8117927_0 PFAM aminotransferase class I and II K10206,K14261 - 2.6.1.83 3.41e-201 651.0
HKD2_k127_8117927_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 496.0
HKD2_k127_8117927_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 410.0
HKD2_k127_8151257_0 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 409.0
HKD2_k127_8151257_1 PFAM Alpha beta hydrolase of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 400.0
HKD2_k127_8151257_2 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 303.0
HKD2_k127_8151257_3 Protein of unknown function (DUF1269) - - - 0.000002443 50.0
HKD2_k127_8179727_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1241.0
HKD2_k127_8179727_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 3.173e-205 655.0
HKD2_k127_8179727_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000006165 155.0
HKD2_k127_8179727_11 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000005627 133.0
HKD2_k127_8179727_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000175 128.0
HKD2_k127_8179727_13 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.00000000000000000008989 91.0
HKD2_k127_8179727_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 602.0
HKD2_k127_8179727_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 500.0
HKD2_k127_8179727_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 351.0
HKD2_k127_8179727_5 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 301.0
HKD2_k127_8179727_6 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004479 256.0
HKD2_k127_8179727_7 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004348 211.0
HKD2_k127_8179727_8 Predicted membrane protein (DUF2232) - - - 0.00000000000000000000000000000000000000000000000000000006984 209.0
HKD2_k127_8179727_9 PFAM phosphotransferase KptA Tpt1 K07559 - - 0.0000000000000000000000000000000000000000000000000006162 192.0
HKD2_k127_830264_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 312.0
HKD2_k127_830264_1 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 300.0
HKD2_k127_830264_2 Nitrilase cyanide hydratase K13566 - 3.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
HKD2_k127_830264_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000001917 174.0
HKD2_k127_830264_4 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000001653 106.0
HKD2_k127_830480_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 2.18e-201 634.0
HKD2_k127_830480_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 579.0
HKD2_k127_830480_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 466.0
HKD2_k127_830480_3 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000233 215.0
HKD2_k127_830480_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000004559 173.0
HKD2_k127_830480_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000005669 160.0
HKD2_k127_830480_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.0000000000000000000000000492 118.0
HKD2_k127_8319571_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 4.536e-245 783.0
HKD2_k127_8319571_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
HKD2_k127_8319571_2 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
HKD2_k127_832730_0 Pyridine nucleotide-disulphide oxidoreductase - - - 2.498e-293 917.0
HKD2_k127_832730_1 acyl-CoA dehydrogenase K09456 - - 3.116e-272 848.0
HKD2_k127_832730_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 531.0
HKD2_k127_832730_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 439.0
HKD2_k127_832730_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 330.0
HKD2_k127_832730_5 Tetracycline transcriptional regulator YsiA domain protein K13770 - - 0.000000000000000000000000000000000000000000000000000000000169 209.0
HKD2_k127_832730_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000007008 171.0
HKD2_k127_832730_7 4Fe-4S dicluster domain - - - 0.0000000000001772 72.0
HKD2_k127_8366975_0 FAD binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1293.0
HKD2_k127_8366975_1 ATP-dependent helicase K03579 - 3.6.4.13 4.37e-293 923.0
HKD2_k127_8366975_2 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 589.0
HKD2_k127_8366975_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 410.0
HKD2_k127_8366975_4 manually curated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 311.0
HKD2_k127_8366975_5 TIGRFAM hydrogenase maturation protease K00442 - - 0.000000000000000000000000000000000000000004892 162.0
HKD2_k127_8366975_6 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000001029 126.0
HKD2_k127_8366975_7 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000004289 111.0
HKD2_k127_8366975_8 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000004557 100.0
HKD2_k127_8366975_9 TIGRFAM DNA binding domain, excisionase family K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000002539 83.0
HKD2_k127_8388378_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.525e-296 930.0
HKD2_k127_8388378_1 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 505.0
HKD2_k127_8388378_2 RimK-like ATP-grasp domain K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 325.0
HKD2_k127_8388378_3 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003539 256.0
HKD2_k127_8388378_4 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000004716 237.0
HKD2_k127_8388378_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000003057 140.0
HKD2_k127_8388378_6 - - - - 0.0000001656 58.0
HKD2_k127_8391847_0 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 320.0
HKD2_k127_8391847_1 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 321.0
HKD2_k127_8391847_2 FHA domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 315.0
HKD2_k127_8391847_3 Flavin reductase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001096 238.0
HKD2_k127_8391847_4 protein possibly involved in utilization of glycolate and propanediol - - - 0.00000000000000000000000000000000000000000000000001777 183.0
HKD2_k127_8391847_5 DsrE/DsrF-like family K06039 - - 0.000000000000000000000000000000000000000007324 158.0
HKD2_k127_8391847_6 GGDEF domain - - - 0.00003002 48.0
HKD2_k127_8481267_0 oxidase subunit 1 K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 1.19e-235 738.0
HKD2_k127_8481267_1 TIGRFAM ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD K16013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 581.0
HKD2_k127_8481267_10 COG4987 ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components K16012 - - 0.0000000000000000000000000000000000000000000006194 178.0
HKD2_k127_8481267_11 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000001868 148.0
HKD2_k127_8481267_12 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000000263 112.0
HKD2_k127_8481267_13 Membrane bound YbgT-like protein K00424 - 1.10.3.14 0.00000000002734 65.0
HKD2_k127_8481267_14 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0001951 44.0
HKD2_k127_8481267_2 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 510.0
HKD2_k127_8481267_3 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 405.0
HKD2_k127_8481267_4 PFAM major facilitator superfamily MFS_1 K08161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 399.0
HKD2_k127_8481267_5 methyltransferase K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 361.0
HKD2_k127_8481267_6 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001394 280.0
HKD2_k127_8481267_7 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004739 278.0
HKD2_k127_8481267_8 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002768 275.0
HKD2_k127_8481267_9 Extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002097 269.0
HKD2_k127_8558760_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00244,K00278 - 1.3.5.4,1.4.3.16 8.067e-271 843.0
HKD2_k127_8558760_1 phosphorelay signal transduction system K02584,K12266,K15836,K21009 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 511.0
HKD2_k127_8558760_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 485.0
HKD2_k127_8558760_3 Cytochrome b/b6/petB K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 370.0
HKD2_k127_8558760_4 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000002246 253.0
HKD2_k127_8567483_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 417.0
HKD2_k127_8567483_1 Stage II sporulation K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 298.0
HKD2_k127_8580038_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 484.0
HKD2_k127_8580038_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 356.0
HKD2_k127_8580038_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000002848 180.0
HKD2_k127_8580038_3 - - - - 0.00000000000000000000000006252 117.0
HKD2_k127_8580038_5 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000009259 56.0
HKD2_k127_8585044_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 601.0
HKD2_k127_8585044_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 512.0
HKD2_k127_8585044_2 lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 295.0
HKD2_k127_8585044_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001922 279.0
HKD2_k127_8585044_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000005421 220.0
HKD2_k127_8585044_5 Phosphopantetheine attachment site - - - 0.000000000000000005032 87.0
HKD2_k127_8585044_6 B12 binding domain - - - 0.00000001081 57.0
HKD2_k127_8748083_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1047.0
HKD2_k127_8748083_1 Sodium:sulfate symporter transmembrane region - - - 1.726e-229 724.0
HKD2_k127_8748083_10 hydrolase K01048 - 3.1.1.5 0.0006148 46.0
HKD2_k127_8748083_2 transporter K12942 - - 1.462e-206 655.0
HKD2_k127_8748083_3 M42 glutamyl aminopeptidase K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 548.0
HKD2_k127_8748083_4 PFAM Amidohydrolase 2 K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 390.0
HKD2_k127_8748083_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 376.0
HKD2_k127_8748083_6 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 359.0
HKD2_k127_8748083_7 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005718 288.0
HKD2_k127_8748083_8 META domain K03668 - - 0.000000000000000000000000000000000000000000000001089 185.0
HKD2_k127_8748083_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00005495 48.0
HKD2_k127_8796187_0 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 578.0
HKD2_k127_8796187_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 503.0
HKD2_k127_8796187_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000001608 179.0
HKD2_k127_8796187_11 PFAM adenylate cyclase K05873 - 4.6.1.1 0.00000000000000000000000000000000000000000000003227 178.0
HKD2_k127_8796187_12 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000001261 65.0
HKD2_k127_8796187_13 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000009253 64.0
HKD2_k127_8796187_14 - - - - 0.000000102 64.0
HKD2_k127_8796187_2 4Fe-4S double cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 380.0
HKD2_k127_8796187_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 326.0
HKD2_k127_8796187_4 Allophanate hydrolase subunit 2 K06350 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000412 293.0
HKD2_k127_8796187_5 LamB/YcsF family K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004776 292.0
HKD2_k127_8796187_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002706 267.0
HKD2_k127_8796187_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006236 218.0
HKD2_k127_8796187_8 Allophanate hydrolase subunit 1 K01457,K06351,K07160 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000001898 217.0
HKD2_k127_8796187_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000002643 190.0
HKD2_k127_8816192_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 550.0
HKD2_k127_8816192_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 330.0
HKD2_k127_8816192_2 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 319.0
HKD2_k127_8816192_3 Ecotin K08276 - - 0.00000000000000000000000000000000000000000000000000000000003081 212.0
HKD2_k127_8816192_4 - - - - 0.000002982 55.0
HKD2_k127_8874117_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.346e-296 921.0
HKD2_k127_8874117_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 1.632e-256 820.0
HKD2_k127_8874117_10 PFAM aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000005383 228.0
HKD2_k127_8874117_11 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000000000000000001226 130.0
HKD2_k127_8874117_12 - - - - 0.0000000000000000000000000001367 118.0
HKD2_k127_8874117_13 - - - - 0.0000000002441 74.0
HKD2_k127_8874117_2 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 570.0
HKD2_k127_8874117_3 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 554.0
HKD2_k127_8874117_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 426.0
HKD2_k127_8874117_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 419.0
HKD2_k127_8874117_6 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001694 268.0
HKD2_k127_8874117_7 protein tyrosine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001374 258.0
HKD2_k127_8874117_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000004489 249.0
HKD2_k127_8874117_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000002361 211.0
HKD2_k127_8950277_0 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 352.0
HKD2_k127_8950277_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006793 287.0
HKD2_k127_8950277_3 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000002439 261.0
HKD2_k127_8950277_4 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000001315 233.0
HKD2_k127_8950277_5 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000000000000000000001183 172.0
HKD2_k127_8950277_6 - K09986 - - 0.00000000000000000000000000000000000000159 152.0
HKD2_k127_8950277_7 nucleotidyltransferase activity - - - 0.00000000000000000000000002746 125.0
HKD2_k127_8950277_8 EthD domain - - - 0.00000000000000000000008364 101.0
HKD2_k127_8950277_9 - - - - 0.0000000000000000000158 96.0
HKD2_k127_8958626_0 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 429.0
HKD2_k127_8958626_1 CoA-transferase activity K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 404.0
HKD2_k127_8958626_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 344.0
HKD2_k127_8958626_3 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 350.0
HKD2_k127_8961651_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 488.0
HKD2_k127_8961651_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 372.0
HKD2_k127_8961651_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 305.0
HKD2_k127_8961651_3 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001717 260.0
HKD2_k127_8961651_4 TIGRFAM regulatory protein, FmdB family - - - 0.0000000000000000000000000000000000000000008671 158.0
HKD2_k127_9025176_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 617.0
HKD2_k127_9025176_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 439.0
HKD2_k127_9025176_2 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000324 170.0
HKD2_k127_9025176_3 Universal stress protein family - - - 0.0000000000000000000001115 100.0
HKD2_k127_9042780_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.485e-280 867.0
HKD2_k127_9042780_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.94e-276 854.0
HKD2_k127_9042780_10 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000002482 252.0
HKD2_k127_9042780_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000001383 217.0
HKD2_k127_9042780_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000007103 169.0
HKD2_k127_9042780_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000001688 168.0
HKD2_k127_9042780_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000004879 118.0
HKD2_k127_9042780_15 - K03571 - - 0.00000000000000006624 94.0
HKD2_k127_9042780_16 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000002448 80.0
HKD2_k127_9042780_17 - - - - 0.00000000000000131 76.0
HKD2_k127_9042780_19 - - - - 0.00000006821 57.0
HKD2_k127_9042780_2 Endoribonuclease that initiates mRNA decay K18682 - - 1.394e-237 748.0
HKD2_k127_9042780_20 - - - - 0.00001403 53.0
HKD2_k127_9042780_3 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 1.583e-213 681.0
HKD2_k127_9042780_4 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 583.0
HKD2_k127_9042780_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 585.0
HKD2_k127_9042780_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 441.0
HKD2_k127_9042780_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 406.0
HKD2_k127_9042780_8 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 325.0
HKD2_k127_9042780_9 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001271 257.0
HKD2_k127_9044375_0 PFAM peptidase - - - 1.129e-202 649.0
HKD2_k127_9044375_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 342.0
HKD2_k127_9044375_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000005651 244.0
HKD2_k127_9044375_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000005215 153.0
HKD2_k127_9044375_4 - - - - 0.0000000004664 71.0
HKD2_k127_9046208_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.874e-310 968.0
HKD2_k127_9046208_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02470,K02622 - 5.99.1.3 6.248e-285 887.0
HKD2_k127_9046208_10 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000005034 138.0
HKD2_k127_9046208_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000003281 76.0
HKD2_k127_9046208_12 - - - - 0.0003596 49.0
HKD2_k127_9046208_2 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 447.0
HKD2_k127_9046208_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 407.0
HKD2_k127_9046208_4 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 368.0
HKD2_k127_9046208_5 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 337.0
HKD2_k127_9046208_6 Putative RNA methylase family UPF0020 K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007414 270.0
HKD2_k127_9046208_7 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000007947 257.0
HKD2_k127_9046208_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000001494 179.0
HKD2_k127_9046208_9 - - - - 0.000000000000000000000000000000000000000001194 160.0
HKD2_k127_9071127_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 550.0
HKD2_k127_9071127_1 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 543.0
HKD2_k127_9071127_10 SMART Cold shock protein K03704 - - 0.00000000000000000000004695 102.0
HKD2_k127_9071127_2 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 511.0
HKD2_k127_9071127_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 443.0
HKD2_k127_9071127_4 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 337.0
HKD2_k127_9071127_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
HKD2_k127_9071127_6 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 325.0
HKD2_k127_9071127_7 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000006904 234.0
HKD2_k127_9071127_8 Stage II sporulation K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000001099 241.0
HKD2_k127_9071127_9 SMART Cold shock protein K03704 - - 0.0000000000000000000000004742 106.0
HKD2_k127_9098850_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 514.0
HKD2_k127_9098850_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 435.0
HKD2_k127_9098850_2 PFAM Xylose isomerase domain protein TIM barrel K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 383.0
HKD2_k127_9098850_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 323.0
HKD2_k127_9098850_4 2-keto-3-deoxy-L-rhamnonate aldolase activity K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
HKD2_k127_9098850_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001136 202.0
HKD2_k127_9098850_6 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000003083 206.0
HKD2_k127_9098850_7 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000002099 185.0
HKD2_k127_9152721_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1013.0
HKD2_k127_9152721_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 314.0
HKD2_k127_9152721_2 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 305.0
HKD2_k127_9152721_3 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003497 269.0
HKD2_k127_9152721_4 PFAM transcription factor CarD K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002246 247.0
HKD2_k127_9152721_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000006624 136.0
HKD2_k127_9152721_6 Part of a membrane complex involved in electron transport K03612 - - 0.00007463 45.0
HKD2_k127_9184400_0 dipeptide transport K02035 - - 5.927e-279 866.0
HKD2_k127_9184400_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 7.367e-202 640.0
HKD2_k127_9184400_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 426.0
HKD2_k127_9184400_11 PFAM Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 400.0
HKD2_k127_9184400_12 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 392.0
HKD2_k127_9184400_13 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 400.0
HKD2_k127_9184400_14 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 330.0
HKD2_k127_9184400_15 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001056 278.0
HKD2_k127_9184400_16 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001238 251.0
HKD2_k127_9184400_17 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000001015 228.0
HKD2_k127_9184400_18 Domain of unknown function (DUF4392) - - - 0.0000000000000000000000001385 109.0
HKD2_k127_9184400_19 Class III cytochrome C family - - - 0.00000000000000000001619 107.0
HKD2_k127_9184400_2 nitrogen compound transport K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 514.0
HKD2_k127_9184400_20 acetyltransferase - - - 0.00000000000000000003076 96.0
HKD2_k127_9184400_21 GntR family - - - 0.0000000000000000001437 98.0
HKD2_k127_9184400_22 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000001094 80.0
HKD2_k127_9184400_23 histidine kinase A domain protein - - - 0.000000009495 68.0
HKD2_k127_9184400_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 506.0
HKD2_k127_9184400_4 ABC transporter, permease protein K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 516.0
HKD2_k127_9184400_5 Major Facilitator Superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 471.0
HKD2_k127_9184400_6 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 451.0
HKD2_k127_9184400_7 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 449.0
HKD2_k127_9184400_8 Peptidase dimerisation domain K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 455.0
HKD2_k127_9184400_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 449.0
HKD2_k127_9230383_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.546e-271 852.0
HKD2_k127_9230383_1 TIGRFAM TRAP transporter, DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 445.0
HKD2_k127_9230383_10 phosphonoacetaldehyde hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 314.0
HKD2_k127_9230383_11 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 310.0
HKD2_k127_9230383_12 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 291.0
HKD2_k127_9230383_13 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002674 284.0
HKD2_k127_9230383_14 glycolate biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 282.0
HKD2_k127_9230383_15 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003074 284.0
HKD2_k127_9230383_16 PFAM Haloacid dehalogenase-like hydrolase K01091,K22292 - 3.1.3.105,3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000006411 255.0
HKD2_k127_9230383_17 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000001224 233.0
HKD2_k127_9230383_18 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003416 227.0
HKD2_k127_9230383_19 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000003865 205.0
HKD2_k127_9230383_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 404.0
HKD2_k127_9230383_20 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000003482 179.0
HKD2_k127_9230383_21 RpiB LacA LacB family K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000004727 176.0
HKD2_k127_9230383_22 universal stress protein - - - 0.0000000000000000000000000000000000000004614 154.0
HKD2_k127_9230383_24 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000001313 157.0
HKD2_k127_9230383_25 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000003057 140.0
HKD2_k127_9230383_26 PHP domain protein - - - 0.000000000000000000000000006017 124.0
HKD2_k127_9230383_27 myo-inosose-2 dehydratase activity - - - 0.000001533 60.0
HKD2_k127_9230383_3 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 403.0
HKD2_k127_9230383_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 379.0
HKD2_k127_9230383_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 392.0
HKD2_k127_9230383_6 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009271 336.0
HKD2_k127_9230383_7 Binding-protein-dependent transport system inner membrane component K02033,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 312.0
HKD2_k127_9230383_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 308.0
HKD2_k127_9230383_9 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 306.0
HKD2_k127_9264354_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 628.0
HKD2_k127_9264354_1 Psort location CytoplasmicMembrane, score 10.00 K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 616.0
HKD2_k127_9264354_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 416.0
HKD2_k127_9264354_3 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 342.0
HKD2_k127_9264354_4 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002227 249.0
HKD2_k127_9264354_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000002033 196.0
HKD2_k127_9264354_6 L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000001681 194.0
HKD2_k127_9264354_7 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000006068 89.0
HKD2_k127_9264354_8 Isochorismatase family - - - 0.00000007674 53.0
HKD2_k127_9317792_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 602.0
HKD2_k127_9317792_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 522.0
HKD2_k127_9317792_10 C4-dicarboxylate ABC transporter permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 314.0
HKD2_k127_9317792_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 297.0
HKD2_k127_9317792_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000002076 234.0
HKD2_k127_9317792_13 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000128 109.0
HKD2_k127_9317792_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 458.0
HKD2_k127_9317792_3 nitrogen compound transport K02033,K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 429.0
HKD2_k127_9317792_4 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 352.0
HKD2_k127_9317792_5 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 340.0
HKD2_k127_9317792_6 Protein of unknown function (DUF1445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 328.0
HKD2_k127_9317792_7 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 344.0
HKD2_k127_9317792_8 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 345.0
HKD2_k127_9317792_9 C4-dicarboxylate ABC transporter, substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 323.0
HKD2_k127_9330344_0 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 612.0
HKD2_k127_9330344_1 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 464.0
HKD2_k127_9330344_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 404.0
HKD2_k127_9330344_3 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 359.0
HKD2_k127_9330344_4 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 309.0
HKD2_k127_9330344_5 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001788 276.0
HKD2_k127_9330344_6 amino acid ABC transporter K02029 - - 0.0000000000000000000008144 98.0
HKD2_k127_9335535_0 Cytochrome c554 and c-prime - - - 1.106e-198 627.0
HKD2_k127_9335535_1 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 559.0
HKD2_k127_9335535_2 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 353.0
HKD2_k127_9335535_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 280.0
HKD2_k127_9335535_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001915 281.0
HKD2_k127_9335535_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000001972 180.0
HKD2_k127_9335535_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000006565 141.0
HKD2_k127_9335535_7 response regulator - - - 0.000000000005143 71.0
HKD2_k127_9339688_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 507.0
HKD2_k127_9339688_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 351.0
HKD2_k127_9339688_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001387 289.0
HKD2_k127_9339688_3 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000000000000000000000000000000009268 200.0
HKD2_k127_9339688_4 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.000000000000000000000000000000000000000000000004748 184.0
HKD2_k127_9339688_5 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000003007 179.0
HKD2_k127_9339688_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000411 153.0
HKD2_k127_9339688_7 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000002774 141.0
HKD2_k127_9339688_8 arylsulfatase activity - - - 0.000000002609 70.0
HKD2_k127_935928_0 Dehydrogenase E1 component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 379.0
HKD2_k127_935928_1 Dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 371.0
HKD2_k127_935928_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000007109 255.0
HKD2_k127_935928_3 Dehydrogenase K00382 - 1.8.1.4 0.000000000000005631 78.0
HKD2_k127_9391242_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.135e-205 657.0
HKD2_k127_9391242_1 Domain of unknown function (DUF3390) K18929 - - 4.808e-198 628.0
HKD2_k127_9391242_10 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 341.0
HKD2_k127_9391242_11 PFAM Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 297.0
HKD2_k127_9391242_12 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009509 281.0
HKD2_k127_9391242_13 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000004248 238.0
HKD2_k127_9391242_14 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000513 234.0
HKD2_k127_9391242_15 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000002778 191.0
HKD2_k127_9391242_16 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000002051 175.0
HKD2_k127_9391242_17 Histidine kinase - - - 0.0000000000000000000000000000000000000000003227 173.0
HKD2_k127_9391242_18 TIGRFAM thiW protein - - - 0.000000000000000000000000000000000005721 143.0
HKD2_k127_9391242_19 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000003738 149.0
HKD2_k127_9391242_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 519.0
HKD2_k127_9391242_20 Transcriptional regulator - - - 0.000000000000000000000000000000002841 147.0
HKD2_k127_9391242_21 AAA domain, putative AbiEii toxin, Type IV TA system K16786,K16787 - - 0.0000000000000000000000002053 117.0
HKD2_k127_9391242_22 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system K15555 - - 0.000000000000000006553 93.0
HKD2_k127_9391242_23 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000005036 56.0
HKD2_k127_9391242_3 protein conserved in bacteria K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 471.0
HKD2_k127_9391242_4 formyl-CoA transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 449.0
HKD2_k127_9391242_5 SMP-30/Gluconolaconase/LRE-like region K01053,K02352 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 432.0
HKD2_k127_9391242_6 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 448.0
HKD2_k127_9391242_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 379.0
HKD2_k127_9391242_8 Belongs to the alpha-IPM synthase homocitrate synthase family K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 323.0
HKD2_k127_9391242_9 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 318.0
HKD2_k127_9394094_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 1.135e-198 625.0
HKD2_k127_9394094_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 471.0
HKD2_k127_9394094_2 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 342.0
HKD2_k127_9465050_0 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 413.0
HKD2_k127_9465050_1 Gtr1/RagA G protein conserved region K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
HKD2_k127_9465050_2 Putative RNA methylase family UPF0020 K07444 - - 0.00000000000000000000000000000573 124.0
HKD2_k127_9465050_3 PFAM Ankyrin - - - 0.0000000000000002084 85.0
HKD2_k127_9550236_0 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 533.0
HKD2_k127_9550236_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 487.0
HKD2_k127_9550236_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000008176 209.0
HKD2_k127_9550236_11 Universal stress protein family - - - 0.0000000000000000000000000000000000000001058 156.0
HKD2_k127_9550236_12 signal transduction histidine kinase - - - 0.000000000000000000000146 111.0
HKD2_k127_9550236_13 - - - - 0.0000000000000000000004969 113.0
HKD2_k127_9550236_14 sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000003123 88.0
HKD2_k127_9550236_15 DsrC like protein K11179,K17218 - 1.8.5.4 0.00000000000001613 83.0
HKD2_k127_9550236_17 - - - - 0.0001254 46.0
HKD2_k127_9550236_2 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 473.0
HKD2_k127_9550236_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 475.0
HKD2_k127_9550236_4 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 376.0
HKD2_k127_9550236_5 TIGRFAM tyrosine recombinase XerD K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 376.0
HKD2_k127_9550236_6 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 322.0
HKD2_k127_9550236_7 helix_turn_helix, Lux Regulon K02479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
HKD2_k127_9550236_8 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000007799 223.0
HKD2_k127_9550236_9 Prolyl oligopeptidase family K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000003008 207.0
HKD2_k127_955711_0 Peptidase family M1 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 570.0
HKD2_k127_955711_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 301.0
HKD2_k127_955711_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000853 268.0
HKD2_k127_955711_3 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000004411 227.0
HKD2_k127_955711_4 peptidylprolyl K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000001397 206.0
HKD2_k127_955711_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001085 181.0
HKD2_k127_955711_6 - - - - 0.000000000000000000000000000001416 130.0
HKD2_k127_955711_7 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000001029 123.0
HKD2_k127_955711_8 repeat-containing protein - - - 0.0002397 52.0
HKD2_k127_9558053_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 1.003e-224 703.0
HKD2_k127_9558053_1 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 559.0
HKD2_k127_9558053_2 NUBPL iron-transfer P-loop NTPase K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 468.0
HKD2_k127_9558053_3 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 380.0
HKD2_k127_9558053_4 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 371.0
HKD2_k127_9558053_5 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001907 250.0
HKD2_k127_9558053_6 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000001889 229.0
HKD2_k127_9558053_7 PFAM conserved K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000001468 173.0
HKD2_k127_9597407_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K19594 - - 0.0 1228.0
HKD2_k127_9597407_1 outer membrane efflux - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 544.0
HKD2_k127_9597407_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 520.0
HKD2_k127_9597407_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 361.0
HKD2_k127_9597407_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 299.0
HKD2_k127_9597407_5 Glycine-zipper domain - - - 0.00000000000000000000000000000000002921 138.0
HKD2_k127_9597407_6 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000337 83.0
HKD2_k127_9608346_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1078.0
HKD2_k127_9608346_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 606.0
HKD2_k127_9608346_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000001745 170.0
HKD2_k127_9608346_3 HDOD domain - - - 0.000000000000000000000000000000000000000007928 172.0
HKD2_k127_9608346_4 HDOD domain - - - 0.00000000000000000000000000000000000008731 160.0
HKD2_k127_9608346_5 - - - - 0.00000000000000000000000000000000003277 139.0
HKD2_k127_9608346_6 Diguanylate cyclase - - - 0.0000000000000000000000000000004075 139.0
HKD2_k127_9608346_7 HD domain - - - 0.000000000000000000000000005285 126.0
HKD2_k127_9608346_8 - - - - 0.000000000000000001018 100.0
HKD2_k127_9608346_9 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000009837 85.0
HKD2_k127_966362_0 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 464.0
HKD2_k127_966362_1 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 438.0
HKD2_k127_966362_2 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 306.0
HKD2_k127_966362_3 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000222 219.0
HKD2_k127_9693829_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1060.0
HKD2_k127_9693829_1 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 7.746e-304 946.0
HKD2_k127_9693829_10 - - - - 0.000000000000000000000000003202 119.0
HKD2_k127_9693829_11 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000003405 108.0
HKD2_k127_9693829_13 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0002356 43.0
HKD2_k127_9693829_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.608e-300 929.0
HKD2_k127_9693829_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.296e-242 771.0
HKD2_k127_9693829_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 542.0
HKD2_k127_9693829_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 501.0
HKD2_k127_9693829_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 380.0
HKD2_k127_9693829_7 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001385 283.0
HKD2_k127_9693829_8 PFAM purine or other phosphorylase family 1 - - - 0.0000000000000000000000000000000000000000000000000006436 192.0
HKD2_k127_9693829_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000006095 139.0
HKD2_k127_9723496_0 Penicillin-binding Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 355.0
HKD2_k127_9723496_1 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001618 254.0
HKD2_k127_9723496_2 succinyl-diaminopimelate desuccinylase activity K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000002381 256.0
HKD2_k127_9723496_3 PilZ domain - - - 0.000000000000001032 83.0
HKD2_k127_9743_0 Receptor family ligand binding region - - - 3.004e-195 617.0
HKD2_k127_9743_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 452.0
HKD2_k127_9743_2 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 475.0
HKD2_k127_9743_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 441.0
HKD2_k127_9743_4 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 362.0
HKD2_k127_9743_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 302.0
HKD2_k127_9743_6 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 313.0
HKD2_k127_9864713_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 593.0
HKD2_k127_9864713_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 527.0
HKD2_k127_9864713_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 425.0
HKD2_k127_9864713_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 336.0
HKD2_k127_9864713_4 Glucosamine-6-phosphate K02564 - 3.5.99.6 0.0000000000000000000000000000000002334 136.0
HKD2_k127_9864713_6 Tripartite tricarboxylate transporter TctB family - - - 0.0009183 48.0
HKD2_k127_9865974_0 TIGRFAM Ammonium transporter K03320 - - 1.815e-237 749.0
HKD2_k127_9865974_1 TIGRFAM ammonium transporter K03320 - - 1.718e-198 629.0
HKD2_k127_9865974_10 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000001532 137.0
HKD2_k127_9865974_11 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000004297 91.0
HKD2_k127_9865974_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 1.957e-198 642.0
HKD2_k127_9865974_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 591.0
HKD2_k127_9865974_4 UV-endonuclease UvdE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 376.0
HKD2_k127_9865974_5 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 297.0
HKD2_k127_9865974_6 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000003524 254.0
HKD2_k127_9865974_7 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000001289 233.0
HKD2_k127_9865974_8 Putative molybdenum carrier - - - 0.0000000000000000000000000000000000000000000000000000001125 205.0
HKD2_k127_9865974_9 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000001401 171.0
HKD2_k127_9913874_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 611.0
HKD2_k127_9913874_1 3-hydroxyacyl-coa dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007283 285.0
HKD2_k127_9913874_2 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008678 269.0
HKD2_k127_9913874_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 273.0
HKD2_k127_9913874_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005425 268.0
HKD2_k127_9913874_5 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000007016 200.0
HKD2_k127_9913874_6 PFAM Branched-chain amino acid transport system permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000007573 205.0
HKD2_k127_9913874_7 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000009048 162.0
HKD2_k127_9913874_8 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000008774 50.0
HKD2_k127_9918333_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 1.806e-195 620.0
HKD2_k127_9918333_1 formate dehydrogenase (NAD+) activity K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 306.0
HKD2_k127_9918333_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K18007 - 1.12.1.2,1.8.98.5 0.00000000000000000000000000000000000000000000000000004357 200.0
HKD2_k127_9949315_0 PFAM Alpha beta hydrolase K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 434.0
HKD2_k127_9949315_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 418.0
HKD2_k127_9949315_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 360.0
HKD2_k127_9949315_3 Permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 346.0
HKD2_k127_9949315_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 355.0
HKD2_k127_9949315_5 ABC transporter, permease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 332.0