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Overview

ID MAG01794
Name HKD2_bin.37
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_B
Class Binatia
Order DP-6
Family DP-6
Genus DATJZY01
Species
Assembly information
Completeness (%) 81.77
Contamination (%) 2.39
GC content (%) 72.0
N50 (bp) 27,153
Genome size (bp) 4,114,495

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3517

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_1011515_0 Belongs to the MenA family. Type 1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 357.0
HKD2_k127_1011515_1 Monooxygenase fad-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 340.0
HKD2_k127_1011515_2 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 295.0
HKD2_k127_1011515_3 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001056 278.0
HKD2_k127_1011515_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000002956 240.0
HKD2_k127_1011515_5 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000001356 197.0
HKD2_k127_1011515_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002833 150.0
HKD2_k127_1011515_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000002664 136.0
HKD2_k127_1011515_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000006493 123.0
HKD2_k127_10163826_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.565e-261 835.0
HKD2_k127_10163826_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 394.0
HKD2_k127_10163826_10 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000005031 191.0
HKD2_k127_10163826_11 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.0000000000000000000000000000000000000000003009 169.0
HKD2_k127_10163826_12 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000007357 136.0
HKD2_k127_10163826_13 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000001922 130.0
HKD2_k127_10163826_14 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000001126 86.0
HKD2_k127_10163826_15 O-Antigen ligase - - - 0.0000000005008 72.0
HKD2_k127_10163826_16 Glycosyl transferase family 2 - - - 0.00001845 56.0
HKD2_k127_10163826_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 376.0
HKD2_k127_10163826_3 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 366.0
HKD2_k127_10163826_4 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007703 328.0
HKD2_k127_10163826_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000263 281.0
HKD2_k127_10163826_6 PFAM sugar transferase K13012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002205 268.0
HKD2_k127_10163826_7 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000001675 271.0
HKD2_k127_10163826_8 domain protein - - - 0.00000000000000000000000000000000000000000000000000000002407 207.0
HKD2_k127_10163826_9 SPTR Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000008257 204.0
HKD2_k127_103265_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1816.0
HKD2_k127_103265_1 methylcrotonoyl-CoA carboxylase activity K01969,K17425 GO:0002169,GO:0003674,GO:0003824,GO:0004485,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006520,GO:0006551,GO:0006552,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0007563,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015936,GO:0016043,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031974,GO:0032787,GO:0032991,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0050789,GO:0050793,GO:0051186,GO:0051239,GO:0051259,GO:0051291,GO:0055086,GO:0065003,GO:0065007,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0098798,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1905202,GO:2000026 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 611.0
HKD2_k127_103265_10 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 418.0
HKD2_k127_103265_11 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 403.0
HKD2_k127_103265_12 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 387.0
HKD2_k127_103265_13 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 377.0
HKD2_k127_103265_14 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 372.0
HKD2_k127_103265_15 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 351.0
HKD2_k127_103265_16 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007577 337.0
HKD2_k127_103265_17 Starch synthase catalytic K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 353.0
HKD2_k127_103265_18 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 331.0
HKD2_k127_103265_19 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 331.0
HKD2_k127_103265_2 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 563.0
HKD2_k127_103265_20 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 327.0
HKD2_k127_103265_21 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 321.0
HKD2_k127_103265_22 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 319.0
HKD2_k127_103265_23 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 298.0
HKD2_k127_103265_24 TIGRFAM metallophosphoesterase, MG_246 BB_0505 family K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 291.0
HKD2_k127_103265_25 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 285.0
HKD2_k127_103265_26 SecD/SecF GG Motif K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003706 280.0
HKD2_k127_103265_27 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007459 277.0
HKD2_k127_103265_28 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000001445 238.0
HKD2_k127_103265_29 enoyl-CoA hydratase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000001222 222.0
HKD2_k127_103265_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 580.0
HKD2_k127_103265_30 Zinc dependent phospholipase C - - - 0.0000000000000000000000000000000000000000000000000000000004682 212.0
HKD2_k127_103265_31 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000003456 178.0
HKD2_k127_103265_32 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000004938 179.0
HKD2_k127_103265_33 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.00000000000000000000000000000000000000000002045 166.0
HKD2_k127_103265_34 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000003487 154.0
HKD2_k127_103265_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000003375 139.0
HKD2_k127_103265_36 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000004937 120.0
HKD2_k127_103265_37 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000009215 117.0
HKD2_k127_103265_38 lipolytic protein G-D-S-L family - - - 0.000000000000000000000008704 114.0
HKD2_k127_103265_39 - - - - 0.0000000000000000000005096 107.0
HKD2_k127_103265_4 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 582.0
HKD2_k127_103265_40 - - - - 0.000000000000000000001664 94.0
HKD2_k127_103265_41 Preprotein translocase subunit K03210 - - 0.0000000000000000005084 91.0
HKD2_k127_103265_42 - - - - 0.00000000000003107 74.0
HKD2_k127_103265_43 Cytochrome c - - - 0.00000000000005898 81.0
HKD2_k127_103265_44 Calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.000002879 61.0
HKD2_k127_103265_45 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768 - 2.7.1.202 0.00004302 56.0
HKD2_k127_103265_5 4-Hydroxyphenylpyruvate dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 514.0
HKD2_k127_103265_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 479.0
HKD2_k127_103265_7 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 460.0
HKD2_k127_103265_8 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 455.0
HKD2_k127_103265_9 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 415.0
HKD2_k127_106755_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 351.0
HKD2_k127_106755_1 Histidine kinase - - - 0.000000000000000000000000000000000000006381 163.0
HKD2_k127_106755_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000003264 143.0
HKD2_k127_113272_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 482.0
HKD2_k127_113272_1 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 353.0
HKD2_k127_113272_10 - - - - 0.000000001842 60.0
HKD2_k127_113272_11 - - - - 0.0002999 44.0
HKD2_k127_113272_12 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0003371 47.0
HKD2_k127_113272_2 Alanine-glyoxylate amino-transferase K03710,K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 329.0
HKD2_k127_113272_3 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000000144 198.0
HKD2_k127_113272_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000001172 187.0
HKD2_k127_113272_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000004098 189.0
HKD2_k127_113272_6 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.00000000000000000000000000000000000000000002444 175.0
HKD2_k127_113272_7 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000009298 179.0
HKD2_k127_113272_8 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000007659 158.0
HKD2_k127_113272_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000006559 112.0
HKD2_k127_114112_0 Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.0 1180.0
HKD2_k127_114112_1 Glucodextranase, domain N K01178 - 3.2.1.3 0.0 1038.0
HKD2_k127_114112_10 COG0657 Esterase lipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 399.0
HKD2_k127_114112_11 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
HKD2_k127_114112_12 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 335.0
HKD2_k127_114112_13 PFAM Sulfotransferase K01014 - 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 332.0
HKD2_k127_114112_14 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 344.0
HKD2_k127_114112_15 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 289.0
HKD2_k127_114112_16 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006729 295.0
HKD2_k127_114112_17 alpha beta - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005625 284.0
HKD2_k127_114112_18 acyl-CoA dehydrogenase K18244 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009032 273.0
HKD2_k127_114112_19 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000673 271.0
HKD2_k127_114112_2 acyl-CoA dehydrogenase - - - 3.188e-240 764.0
HKD2_k127_114112_20 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003647 273.0
HKD2_k127_114112_21 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.0000000000000000000000000000000000000000000000000000000000000000000000001191 271.0
HKD2_k127_114112_22 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000633 249.0
HKD2_k127_114112_23 Sulfotransferase domain K01014 - 2.8.2.1 0.000000000000000000000000000000000000000000000000000000000000003371 239.0
HKD2_k127_114112_24 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000531 217.0
HKD2_k127_114112_25 Diacylglycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000005115 216.0
HKD2_k127_114112_26 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000002484 186.0
HKD2_k127_114112_27 Ethanolamine ammonia-lyase light chain (EutC) K03736 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0009350,GO:0019842,GO:0031419,GO:0032991,GO:0036094,GO:0044424,GO:0044464,GO:0046906,GO:0048037,GO:0097159,GO:1901363,GO:1902494 4.3.1.7 0.0000000000000000000000000000000000000000006783 178.0
HKD2_k127_114112_28 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000009479 168.0
HKD2_k127_114112_29 Flp pilus polar localization response receiver ATPase TadZ, FlhG domain-containing K02282 - - 0.0000000000000000000000000000000000000164 159.0
HKD2_k127_114112_3 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 627.0
HKD2_k127_114112_30 oxidoreductase activity K07114 - - 0.00000000000000000000000000003354 132.0
HKD2_k127_114112_31 Glutathione metabolism K15729 - 5.3.99.3 0.0000000000000000000000001005 113.0
HKD2_k127_114112_32 Extracellular nuclease - - - 0.0000000000000000000000003036 124.0
HKD2_k127_114112_33 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000318 109.0
HKD2_k127_114112_34 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000002992 106.0
HKD2_k127_114112_35 - - - - 0.000000000000000000001734 105.0
HKD2_k127_114112_36 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000002066 87.0
HKD2_k127_114112_37 polygalacturonase activity - - - 0.0000000003817 74.0
HKD2_k127_114112_38 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000631 64.0
HKD2_k127_114112_39 SCP-2 sterol transfer family - - - 0.0002093 49.0
HKD2_k127_114112_4 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 592.0
HKD2_k127_114112_41 Aldehyde dehydrogenase family K00128,K00130 - 1.2.1.3,1.2.1.8 0.0006797 48.0
HKD2_k127_114112_5 malic protein domain protein K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 557.0
HKD2_k127_114112_6 With EutC catalyzes the formation of acetaldehyde and ammonia from ethanolamine K03735,K16785 - 4.3.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 521.0
HKD2_k127_114112_7 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 514.0
HKD2_k127_114112_8 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 472.0
HKD2_k127_114112_9 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 385.0
HKD2_k127_123257_0 Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall K03367 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016208,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0022857,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 346.0
HKD2_k127_123257_1 membrane protein involved in D-alanine export K03739 - - 0.000000000000000000000000000000000000000000000000000000000000000000002871 253.0
HKD2_k127_123257_2 Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall K14188 GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.1.1.13 0.0000000000003162 71.0
HKD2_k127_12990_0 elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 451.0
HKD2_k127_12990_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 343.0
HKD2_k127_12990_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000003972 184.0
HKD2_k127_12990_3 Thiol disulfide interchange protein dsbA - - - 0.00000000000000000000000000000000000000000000005525 185.0
HKD2_k127_12990_4 VanZ like family - - - 0.00000000000000000000002617 104.0
HKD2_k127_12990_5 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000003808 96.0
HKD2_k127_1309625_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 2.219e-315 1001.0
HKD2_k127_1309625_1 PFAM Cytochrome b b6 domain - - - 9.549e-200 644.0
HKD2_k127_1309625_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 539.0
HKD2_k127_1309625_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 446.0
HKD2_k127_1309625_4 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009871 342.0
HKD2_k127_1309625_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 316.0
HKD2_k127_1309625_6 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 302.0
HKD2_k127_1309625_7 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000003986 141.0
HKD2_k127_1309625_8 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000006763 131.0
HKD2_k127_1309625_9 nucleic acid binding K01174 - 3.1.31.1 0.000021 55.0
HKD2_k127_1335531_0 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005152 253.0
HKD2_k127_1335531_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000006173 227.0
HKD2_k127_1335531_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000001885 130.0
HKD2_k127_1335531_4 - - - - 0.000003514 54.0
HKD2_k127_1343447_0 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 283.0
HKD2_k127_1343447_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000105 307.0
HKD2_k127_1343447_10 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.00000000000000002486 96.0
HKD2_k127_1343447_11 Virulence activator alpha C-term - - - 0.000000000000002592 86.0
HKD2_k127_1343447_12 CYTH - - - 0.000000000001261 81.0
HKD2_k127_1343447_13 DnaJ-class molecular chaperone with C-terminal Zn finger - - - 0.00000000001007 76.0
HKD2_k127_1343447_14 BlaR1 peptidase M56 - - - 0.0000000003937 71.0
HKD2_k127_1343447_15 PFAM thioesterase superfamily K07107 - - 0.0000001369 64.0
HKD2_k127_1343447_16 Domain of unknown function (DUF309) K09763 - - 0.0000006427 62.0
HKD2_k127_1343447_17 thioesterase K07107 - - 0.0002526 53.0
HKD2_k127_1343447_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000189 231.0
HKD2_k127_1343447_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008838 228.0
HKD2_k127_1343447_4 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000002674 210.0
HKD2_k127_1343447_5 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000001315 186.0
HKD2_k127_1343447_6 KR domain - - - 0.000000000000000000000000000000000000000002192 167.0
HKD2_k127_1343447_7 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000002773 170.0
HKD2_k127_1343447_8 acetyltransferase - - - 0.000000000000000000158 99.0
HKD2_k127_1343447_9 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000000000000002092 98.0
HKD2_k127_1365330_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 575.0
HKD2_k127_1365330_1 Glycosyl transferase family 2 K00721 GO:0000271,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0030258,GO:0030259,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000008602 271.0
HKD2_k127_1365330_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000003989 216.0
HKD2_k127_1365330_3 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000004583 186.0
HKD2_k127_1367751_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.894e-200 637.0
HKD2_k127_1367751_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 498.0
HKD2_k127_1367751_10 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000003833 54.0
HKD2_k127_1367751_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 379.0
HKD2_k127_1367751_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 349.0
HKD2_k127_1367751_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 297.0
HKD2_k127_1367751_5 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006429 309.0
HKD2_k127_1367751_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000001518 235.0
HKD2_k127_1367751_7 spore coat K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000004334 196.0
HKD2_k127_1367751_8 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000004922 193.0
HKD2_k127_1367751_9 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000004143 162.0
HKD2_k127_1369999_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 517.0
HKD2_k127_1369999_1 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007209 459.0
HKD2_k127_1369999_10 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.000000000000000000000000000000000000000000000002254 196.0
HKD2_k127_1369999_11 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000546 156.0
HKD2_k127_1369999_12 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000005901 145.0
HKD2_k127_1369999_13 - - - - 0.00000000000000000000000000001263 138.0
HKD2_k127_1369999_14 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000009725 106.0
HKD2_k127_1369999_15 PhoQ Sensor - - - 0.000000000000000003803 96.0
HKD2_k127_1369999_16 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000001094 99.0
HKD2_k127_1369999_17 Fibronectin type III - - - 0.00008598 54.0
HKD2_k127_1369999_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 400.0
HKD2_k127_1369999_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 362.0
HKD2_k127_1369999_4 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 375.0
HKD2_k127_1369999_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 342.0
HKD2_k127_1369999_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 331.0
HKD2_k127_1369999_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000003676 252.0
HKD2_k127_1369999_8 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000005671 241.0
HKD2_k127_1369999_9 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.000000000000000000000000000000000000000000000000000003227 212.0
HKD2_k127_1370371_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1228.0
HKD2_k127_1370371_1 Aspartate ammonia-lyase K01744 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 9.748e-283 912.0
HKD2_k127_1370371_10 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 423.0
HKD2_k127_1370371_11 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 348.0
HKD2_k127_1370371_12 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 341.0
HKD2_k127_1370371_13 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 321.0
HKD2_k127_1370371_14 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 291.0
HKD2_k127_1370371_15 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
HKD2_k127_1370371_16 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000007818 244.0
HKD2_k127_1370371_17 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000007376 231.0
HKD2_k127_1370371_18 - - - - 0.0000000000000000000000000000000000000000007034 175.0
HKD2_k127_1370371_19 - - - - 0.00000000000000000000000000000002331 130.0
HKD2_k127_1370371_2 serine dehydratase beta chain K01752 - 4.3.1.17 9.495e-237 747.0
HKD2_k127_1370371_20 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000007824 127.0
HKD2_k127_1370371_21 Phospholipid methyltransferase - - - 0.000000000000000000007002 100.0
HKD2_k127_1370371_22 PFAM Phosphate-selective porin O and P K07221 - - 0.00000000000000000001292 108.0
HKD2_k127_1370371_24 Glycine-zipper domain - - - 0.00000005348 61.0
HKD2_k127_1370371_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 569.0
HKD2_k127_1370371_4 Glutaminase K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 458.0
HKD2_k127_1370371_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 468.0
HKD2_k127_1370371_6 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 449.0
HKD2_k127_1370371_7 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 430.0
HKD2_k127_1370371_8 Predicted Permease Membrane Region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 437.0
HKD2_k127_1370371_9 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 407.0
HKD2_k127_1372188_0 Protein of unknown function, DUF255 K06888 - - 8.945e-204 657.0
HKD2_k127_1372188_1 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 606.0
HKD2_k127_1372188_10 TIGRFAM ABC exporter ATP-binding subunit, DevA family K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 375.0
HKD2_k127_1372188_11 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 305.0
HKD2_k127_1372188_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 318.0
HKD2_k127_1372188_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 313.0
HKD2_k127_1372188_14 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 301.0
HKD2_k127_1372188_15 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 306.0
HKD2_k127_1372188_16 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007769 293.0
HKD2_k127_1372188_17 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000291 287.0
HKD2_k127_1372188_18 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001762 276.0
HKD2_k127_1372188_19 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000173 250.0
HKD2_k127_1372188_2 metal ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 561.0
HKD2_k127_1372188_20 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000002311 223.0
HKD2_k127_1372188_21 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000009256 216.0
HKD2_k127_1372188_22 Inositol monophosphatase family K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.00000000000000000000000000000000000000000000000000003289 212.0
HKD2_k127_1372188_23 - - - - 0.00000000000000000000000000000000000000000000001489 197.0
HKD2_k127_1372188_24 Right handed beta helix region - - - 0.000000000000000000000000000000000000000001354 177.0
HKD2_k127_1372188_25 Cytochrome c mono- and diheme variants - - - 0.000000000000000000000000000000000000001783 171.0
HKD2_k127_1372188_26 PFAM Class I peptide chain release factor - - - 0.000000000000000000000000000000006811 132.0
HKD2_k127_1372188_27 Protein of unknown function (DUF1588) - - - 0.0000000000000000000000000000001405 145.0
HKD2_k127_1372188_28 Chromate resistance exported protein - - - 0.000000000000000000000000000001764 126.0
HKD2_k127_1372188_29 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000003231 124.0
HKD2_k127_1372188_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 493.0
HKD2_k127_1372188_30 Belongs to the TPP enzyme family K01637 - 4.1.3.1 0.000000000000000000000000178 120.0
HKD2_k127_1372188_31 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000007497 122.0
HKD2_k127_1372188_32 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.0000000000000000000002106 105.0
HKD2_k127_1372188_33 glucose sorbosone - - - 0.00000000000000000001023 108.0
HKD2_k127_1372188_34 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000001087 103.0
HKD2_k127_1372188_35 - - - - 0.0000000000000000001455 104.0
HKD2_k127_1372188_36 Protein of unknown function (DUF1501) - - - 0.000000000000000009573 97.0
HKD2_k127_1372188_37 6-phosphogluconolactonase activity - - - 0.000000000000001039 89.0
HKD2_k127_1372188_38 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000002066 64.0
HKD2_k127_1372188_39 - - - - 0.0001824 51.0
HKD2_k127_1372188_4 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 457.0
HKD2_k127_1372188_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 417.0
HKD2_k127_1372188_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 406.0
HKD2_k127_1372188_7 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 413.0
HKD2_k127_1372188_8 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 371.0
HKD2_k127_1372188_9 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 367.0
HKD2_k127_1380319_0 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 536.0
HKD2_k127_1380319_1 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 510.0
HKD2_k127_1380319_2 Acyl-CoA thioesterase K10805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 307.0
HKD2_k127_1380319_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 307.0
HKD2_k127_1380319_4 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003329 287.0
HKD2_k127_1380319_5 Belongs to the long-chain O-acyltransferase family - - - 0.00000000000000000000006199 104.0
HKD2_k127_1380319_6 metalloendopeptidase activity K06261,K08867,K09187,K14972,K20371 - 2.1.1.43,2.7.11.1 0.00000000015 74.0
HKD2_k127_1380319_8 AMP-binding enzyme C-terminal domain K01911,K02549 GO:0003674,GO:0003824,GO:0008150,GO:0008756,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0040007 4.2.1.113,6.2.1.26 0.000001116 53.0
HKD2_k127_1397467_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.841e-239 775.0
HKD2_k127_1397467_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 517.0
HKD2_k127_1397467_10 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000009505 203.0
HKD2_k127_1397467_11 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000002695 184.0
HKD2_k127_1397467_12 YceI-like domain - - - 0.00000000000000000000000000000000000006025 149.0
HKD2_k127_1397467_13 Alpha beta hydrolase fold - - - 0.000000000000000000000000000000000001519 149.0
HKD2_k127_1397467_14 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.0000000000000000000000000000000001274 143.0
HKD2_k127_1397467_15 DSBA-like thioredoxin domain - - - 0.0000000000000000000000007653 116.0
HKD2_k127_1397467_16 COG1108 ABC-type Mn2 Zn2 transport systems permease components K11708 - - 0.000000000000000001379 96.0
HKD2_k127_1397467_17 - - - - 0.00006573 53.0
HKD2_k127_1397467_2 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 426.0
HKD2_k127_1397467_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 375.0
HKD2_k127_1397467_4 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 327.0
HKD2_k127_1397467_5 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 286.0
HKD2_k127_1397467_6 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001347 297.0
HKD2_k127_1397467_7 - K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000004429 240.0
HKD2_k127_1397467_8 TIGRFAM hopanoid biosynthesis associated protein HpnK - - - 0.00000000000000000000000000000000000000000000000000000000000006942 226.0
HKD2_k127_1397467_9 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000001621 231.0
HKD2_k127_1483604_0 PFAM transcriptional regulator domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 610.0
HKD2_k127_1483604_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002919 280.0
HKD2_k127_1483604_2 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000247 165.0
HKD2_k127_1483604_3 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000000002585 126.0
HKD2_k127_1483604_4 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000002811 77.0
HKD2_k127_1483604_5 4Fe-4S binding domain - - - 0.00000006275 57.0
HKD2_k127_1483604_6 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000007893 66.0
HKD2_k127_1509012_0 Amidohydrolase K07045 - - 1.008e-197 619.0
HKD2_k127_1509012_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 604.0
HKD2_k127_1509012_10 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 460.0
HKD2_k127_1509012_11 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 430.0
HKD2_k127_1509012_12 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 373.0
HKD2_k127_1509012_13 von Willebrand factor type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 344.0
HKD2_k127_1509012_14 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 335.0
HKD2_k127_1509012_15 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 329.0
HKD2_k127_1509012_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 330.0
HKD2_k127_1509012_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 305.0
HKD2_k127_1509012_18 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003213 287.0
HKD2_k127_1509012_19 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001034 283.0
HKD2_k127_1509012_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 585.0
HKD2_k127_1509012_20 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000006206 272.0
HKD2_k127_1509012_21 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001711 287.0
HKD2_k127_1509012_22 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000005679 241.0
HKD2_k127_1509012_23 TIM-barrel fold metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001163 252.0
HKD2_k127_1509012_24 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000001693 192.0
HKD2_k127_1509012_25 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000002469 186.0
HKD2_k127_1509012_26 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000001744 165.0
HKD2_k127_1509012_27 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000002839 162.0
HKD2_k127_1509012_28 Oxygen tolerance - - - 0.00000000000000000000000000000000000000328 170.0
HKD2_k127_1509012_29 Thioredoxin-like - - - 0.0000000000000000000000000000000000311 150.0
HKD2_k127_1509012_3 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 576.0
HKD2_k127_1509012_30 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000001529 139.0
HKD2_k127_1509012_31 DoxX-like family K15977 - - 0.00000000000000000000000000000007132 145.0
HKD2_k127_1509012_32 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000544 140.0
HKD2_k127_1509012_33 - - - - 0.00000000000000000000000000001601 136.0
HKD2_k127_1509012_34 glyoxalase III activity - - - 0.00000000000000000000816 97.0
HKD2_k127_1509012_35 cheY-homologous receiver domain - - - 0.00000000000000000004592 94.0
HKD2_k127_1509012_36 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000006816 87.0
HKD2_k127_1509012_37 Methyltransferase domain - - - 0.000000000000000001096 102.0
HKD2_k127_1509012_38 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000009424 98.0
HKD2_k127_1509012_39 tetratricopeptide repeat - - - 0.0000000000003362 84.0
HKD2_k127_1509012_4 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 539.0
HKD2_k127_1509012_40 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000442 71.0
HKD2_k127_1509012_41 Dual specificity phosphatase, catalytic domain - - - 0.00000005987 64.0
HKD2_k127_1509012_42 Hep Hag repeat protein - - - 0.0000000943 66.0
HKD2_k127_1509012_43 protein conserved in bacteria K09986 - - 0.00003951 53.0
HKD2_k127_1509012_44 von Willebrand factor (vWF) type A domain K07114 - - 0.00009972 55.0
HKD2_k127_1509012_45 Rubrerythrin - - - 0.0003437 49.0
HKD2_k127_1509012_5 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 551.0
HKD2_k127_1509012_6 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 470.0
HKD2_k127_1509012_7 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 452.0
HKD2_k127_1509012_8 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 426.0
HKD2_k127_1509012_9 chromate transport K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 428.0
HKD2_k127_1525755_0 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 396.0
HKD2_k127_1525755_1 TIGRFAM TIGR03032 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 404.0
HKD2_k127_1525755_2 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007188 377.0
HKD2_k127_1525755_3 Epimerase dehydratase K19180 - 1.1.1.339 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 361.0
HKD2_k127_1525755_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 342.0
HKD2_k127_1525755_5 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 322.0
HKD2_k127_1525755_6 PFAM O-methyltransferase family 2 K09846 - 2.1.1.210 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 291.0
HKD2_k127_1525755_7 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000003423 213.0
HKD2_k127_1525755_8 Pfam:DUF2029 - - - 0.0000000000000000000000000000001745 143.0
HKD2_k127_1530695_0 PFAM Nitrile hydratase, alpha subunit Thiocyanate hydrolase, gamma subunit K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000002191 256.0
HKD2_k127_1530695_1 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides - - - 0.000000000000000000000000000000000000000000000000000000005645 207.0
HKD2_k127_1530695_2 Nitrile hydratase beta subunit - - - 0.000000000000000000000000003175 115.0
HKD2_k127_1600487_0 Protein of unknown function (DUF3604) - - - 7.109e-244 793.0
HKD2_k127_1600487_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 2.345e-238 754.0
HKD2_k127_1600487_10 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 378.0
HKD2_k127_1600487_11 HAMP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006458 306.0
HKD2_k127_1600487_12 lipid-transfer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006448 265.0
HKD2_k127_1600487_13 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000004517 241.0
HKD2_k127_1600487_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000002431 239.0
HKD2_k127_1600487_15 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000005299 218.0
HKD2_k127_1600487_16 EVE domain - - - 0.0000000000000000000000000000000000000000000000000002506 190.0
HKD2_k127_1600487_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000005946 200.0
HKD2_k127_1600487_18 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000003951 166.0
HKD2_k127_1600487_19 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07264 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016763,GO:0033692,GO:0034637,GO:0034645,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.43 0.0000000000000000000000000000000000000000004595 177.0
HKD2_k127_1600487_2 PFAM AMP-dependent synthetase and ligase K08295 - 6.2.1.32 2.353e-227 718.0
HKD2_k127_1600487_20 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.0000000000000000000000000000000001878 137.0
HKD2_k127_1600487_21 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000005958 139.0
HKD2_k127_1600487_22 acetyltransferase - - - 0.00000000000000000000000000000002421 134.0
HKD2_k127_1600487_23 Cupin 2, conserved barrel domain protein - - - 0.0000000001746 66.0
HKD2_k127_1600487_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000149 66.0
HKD2_k127_1600487_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000111 63.0
HKD2_k127_1600487_3 von Willebrand factor, type A K07114 - - 6.969e-196 638.0
HKD2_k127_1600487_4 DNA-binding response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 587.0
HKD2_k127_1600487_5 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 557.0
HKD2_k127_1600487_6 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 479.0
HKD2_k127_1600487_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 480.0
HKD2_k127_1600487_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 470.0
HKD2_k127_1600487_9 Coenzyme A transferase K01027,K01029,K01032 - 2.8.3.5,2.8.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 389.0
HKD2_k127_1603870_0 Flavoprotein involved in K transport K18229 - 1.14.13.92 1.016e-239 751.0
HKD2_k127_1603870_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 606.0
HKD2_k127_1603870_10 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000005575 131.0
HKD2_k127_1603870_11 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000007594 119.0
HKD2_k127_1603870_12 ABC-2 type transporter K01992 - - 0.000000000000000000000000000249 131.0
HKD2_k127_1603870_13 Haem-binding domain - - - 0.00000007644 64.0
HKD2_k127_1603870_2 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 422.0
HKD2_k127_1603870_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 315.0
HKD2_k127_1603870_4 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 302.0
HKD2_k127_1603870_5 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002076 296.0
HKD2_k127_1603870_6 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001915 281.0
HKD2_k127_1603870_7 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000002359 250.0
HKD2_k127_1603870_8 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000003049 222.0
HKD2_k127_1603870_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000001171 184.0
HKD2_k127_1617028_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.44e-206 663.0
HKD2_k127_1617028_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 385.0
HKD2_k127_1617028_10 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000001473 150.0
HKD2_k127_1617028_11 Sterol carrier protein - - - 0.000000000000000000001582 102.0
HKD2_k127_1617028_13 Serine aminopeptidase, S33 - - - 0.000000000143 74.0
HKD2_k127_1617028_14 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0005811 53.0
HKD2_k127_1617028_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 291.0
HKD2_k127_1617028_3 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000009972 238.0
HKD2_k127_1617028_4 oxidoreductase activity, acting on CH-OH group of donors K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000135 205.0
HKD2_k127_1617028_5 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000001511 208.0
HKD2_k127_1617028_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000004849 202.0
HKD2_k127_1617028_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000004284 171.0
HKD2_k127_1617028_8 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000003501 171.0
HKD2_k127_1617028_9 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000001091 181.0
HKD2_k127_1617825_0 Transposase domain (DUF772) K07487 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 507.0
HKD2_k127_1617825_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000002089 115.0
HKD2_k127_1617825_2 PFAM Cold-shock protein DNA-binding K03704 - - 0.0000000000000000000000007702 108.0
HKD2_k127_1689273_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 377.0
HKD2_k127_1689273_1 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 325.0
HKD2_k127_1689273_10 PA14 domain-containing protein - GO:0005575,GO:0005576 - 0.00000004582 68.0
HKD2_k127_1689273_2 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 337.0
HKD2_k127_1689273_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000005301 278.0
HKD2_k127_1689273_4 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000004505 259.0
HKD2_k127_1689273_5 Isochorismate synthase K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000001476 256.0
HKD2_k127_1689273_6 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000007678 156.0
HKD2_k127_1689273_7 Homologues of snake disintegrins - - - 0.000000000000000000000000862 123.0
HKD2_k127_1689273_8 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000005352 117.0
HKD2_k127_1689273_9 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 GO:0003674,GO:0003824,GO:0016787 4.2.99.20 0.0000000000000000001881 104.0
HKD2_k127_1881692_0 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 467.0
HKD2_k127_1881692_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 314.0
HKD2_k127_1881692_2 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.000000000000000000000000000000000000000000009719 166.0
HKD2_k127_1892258_0 queuine tRNA-ribosyltransferase activity K00773 - 2.4.2.29 1.026e-228 727.0
HKD2_k127_1892258_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 1.289e-197 627.0
HKD2_k127_1892258_10 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000162 138.0
HKD2_k127_1892258_2 VWA domain containing CoxE-like protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 310.0
HKD2_k127_1892258_3 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 287.0
HKD2_k127_1892258_4 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001301 279.0
HKD2_k127_1892258_5 dicarboxylic acid transport K02030,K11102 - - 0.0000000000000000000000000000000000000000000000000000001798 205.0
HKD2_k127_1892258_6 hydrolase K01048 GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 0.0000000000000000000000000000000000000000000000000006605 208.0
HKD2_k127_1892258_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.000000000000000000000000000000000000000000000000009401 196.0
HKD2_k127_1892258_8 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000001769 159.0
HKD2_k127_1892258_9 - - - - 0.000000000000000000000000000000000000005575 164.0
HKD2_k127_1909065_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 451.0
HKD2_k127_1909065_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 372.0
HKD2_k127_1909065_10 cellulase activity - - - 0.00000000000000000004047 104.0
HKD2_k127_1909065_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00004114 54.0
HKD2_k127_1909065_2 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 347.0
HKD2_k127_1909065_3 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 321.0
HKD2_k127_1909065_4 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 308.0
HKD2_k127_1909065_5 PFAM Inward rectifier potassium channel K08715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 311.0
HKD2_k127_1909065_6 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003325 298.0
HKD2_k127_1909065_7 - - - - 0.00000000000000000000000000000000002155 144.0
HKD2_k127_1909065_8 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000002223 130.0
HKD2_k127_1909065_9 CBS domain K04767,K07168,K07182 - - 0.00000000000000000000000007088 123.0
HKD2_k127_1909461_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.564e-270 842.0
HKD2_k127_1909461_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.04e-240 752.0
HKD2_k127_1909461_10 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000001214 130.0
HKD2_k127_1909461_11 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000001262 112.0
HKD2_k127_1909461_12 Belongs to the CDS family - - - 0.000000000000000000000002358 113.0
HKD2_k127_1909461_13 PFAM OsmC family protein - - - 0.00000000000000000003188 102.0
HKD2_k127_1909461_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000000000000002392 90.0
HKD2_k127_1909461_15 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000178 78.0
HKD2_k127_1909461_16 Belongs to the ompA family - - - 0.0000000000002322 80.0
HKD2_k127_1909461_17 Uncharacterized small protein (DUF2292) - - - 0.000000209 54.0
HKD2_k127_1909461_18 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000008861 62.0
HKD2_k127_1909461_2 AAA domain - - - 7.132e-231 743.0
HKD2_k127_1909461_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.863e-200 639.0
HKD2_k127_1909461_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K11381 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 441.0
HKD2_k127_1909461_5 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 425.0
HKD2_k127_1909461_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381,K21416 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 417.0
HKD2_k127_1909461_7 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000024 272.0
HKD2_k127_1909461_8 COG3315 O-Methyltransferase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 243.0
HKD2_k127_1909461_9 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000006509 147.0
HKD2_k127_191023_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 2.167e-237 766.0
HKD2_k127_191023_1 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 599.0
HKD2_k127_191023_10 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 342.0
HKD2_k127_191023_11 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 346.0
HKD2_k127_191023_12 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 343.0
HKD2_k127_191023_13 Arylsulfatase a K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 361.0
HKD2_k127_191023_14 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000123 298.0
HKD2_k127_191023_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 280.0
HKD2_k127_191023_16 Diacylglycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004738 248.0
HKD2_k127_191023_17 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008172 254.0
HKD2_k127_191023_18 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000003988 240.0
HKD2_k127_191023_19 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000272 253.0
HKD2_k127_191023_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 570.0
HKD2_k127_191023_20 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000009935 222.0
HKD2_k127_191023_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000006889 222.0
HKD2_k127_191023_22 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000005434 216.0
HKD2_k127_191023_23 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000000001053 196.0
HKD2_k127_191023_24 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000009321 191.0
HKD2_k127_191023_25 inositol 2-dehydrogenase activity K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000005285 177.0
HKD2_k127_191023_26 TIGRFAM DNA binding domain protein, excisionase family K22491 - - 0.00000000000000000000000000000000000000005579 163.0
HKD2_k127_191023_27 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000005826 156.0
HKD2_k127_191023_28 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.00000000000000000000000000000000001959 137.0
HKD2_k127_191023_29 WYL domain - - - 0.0000000000000000000000000000000001782 145.0
HKD2_k127_191023_3 Protoporphyrinogen oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 553.0
HKD2_k127_191023_30 nucleoside metabolic process - - - 0.00000000000000000000000000001897 130.0
HKD2_k127_191023_31 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000006984 130.0
HKD2_k127_191023_32 HD domain - - - 0.000000000000000005395 88.0
HKD2_k127_191023_33 Alpha beta hydrolase - - - 0.0000000007452 70.0
HKD2_k127_191023_34 cellulase activity K01179 - 3.2.1.4 0.000000002314 70.0
HKD2_k127_191023_35 polysaccharide biosynthetic process K03328,K06409 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000003014 66.0
HKD2_k127_191023_4 Aldo/keto reductase family K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 505.0
HKD2_k127_191023_5 Protein of unknown function (DUF1298) K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 427.0
HKD2_k127_191023_6 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 409.0
HKD2_k127_191023_7 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 404.0
HKD2_k127_191023_8 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 397.0
HKD2_k127_191023_9 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 362.0
HKD2_k127_192467_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 378.0
HKD2_k127_192467_1 Protein conserved in bacteria K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 384.0
HKD2_k127_192467_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 333.0
HKD2_k127_192467_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003832 238.0
HKD2_k127_192467_4 - - - - 0.000000000000007881 83.0
HKD2_k127_192467_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0006215 51.0
HKD2_k127_202651_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 354.0
HKD2_k127_202651_1 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000000000008223 208.0
HKD2_k127_202651_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000002377 148.0
HKD2_k127_202651_3 penicillin binding K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000008414 95.0
HKD2_k127_202651_4 Limonene-1,2-epoxide hydrolase catalytic domain - - - 0.00000000182 64.0
HKD2_k127_2055965_0 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 468.0
HKD2_k127_2055965_1 Sodium/hydrogen exchanger family K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 464.0
HKD2_k127_2055965_10 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001423 271.0
HKD2_k127_2055965_11 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001545 229.0
HKD2_k127_2055965_12 - - - - 0.000000000000000000000000003666 114.0
HKD2_k127_2055965_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 451.0
HKD2_k127_2055965_3 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 397.0
HKD2_k127_2055965_4 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 393.0
HKD2_k127_2055965_5 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 392.0
HKD2_k127_2055965_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 360.0
HKD2_k127_2055965_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family K05991 - 3.2.1.123 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 351.0
HKD2_k127_2055965_8 mechanosensitive ion channel K03442,K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 329.0
HKD2_k127_2055965_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 305.0
HKD2_k127_2091441_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.086e-281 880.0
HKD2_k127_2091441_1 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 568.0
HKD2_k127_2091441_10 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002163 258.0
HKD2_k127_2091441_11 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000008041 244.0
HKD2_k127_2091441_12 Domain of unknown function (DUF4336) - - - 0.00000000000000000000000000000000000000000000000000000000000000002343 230.0
HKD2_k127_2091441_13 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000006487 246.0
HKD2_k127_2091441_14 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.0000000000000000000000000000000000000000000000000000004997 215.0
HKD2_k127_2091441_15 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000008027 199.0
HKD2_k127_2091441_16 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000001172 204.0
HKD2_k127_2091441_17 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000002864 210.0
HKD2_k127_2091441_18 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000008677 192.0
HKD2_k127_2091441_19 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000001069 209.0
HKD2_k127_2091441_2 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 439.0
HKD2_k127_2091441_20 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000001702 191.0
HKD2_k127_2091441_21 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000000003464 190.0
HKD2_k127_2091441_22 Binding-protein-dependent transport system inner membrane component K02050,K15599 - - 0.000000000000000000000000000000000000000000000002656 193.0
HKD2_k127_2091441_23 Histidine kinase - - - 0.0000000000000000000000000000000000000000000006978 181.0
HKD2_k127_2091441_24 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000208 182.0
HKD2_k127_2091441_25 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000009014 163.0
HKD2_k127_2091441_26 sirohydrochlorin cobaltochelatase activity - - - 0.000000000000000000000000000000000000000001175 162.0
HKD2_k127_2091441_27 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000001046 173.0
HKD2_k127_2091441_28 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000001465 132.0
HKD2_k127_2091441_29 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000001788 119.0
HKD2_k127_2091441_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 388.0
HKD2_k127_2091441_30 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000712 121.0
HKD2_k127_2091441_31 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000000000000000000000001374 125.0
HKD2_k127_2091441_32 transcriptional K22295 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000001911 127.0
HKD2_k127_2091441_33 Domain of unknown function (DUF1956) - - - 0.0000000000000000000000004548 113.0
HKD2_k127_2091441_34 HIT domain - - - 0.00000000000000000000003876 104.0
HKD2_k127_2091441_35 secretion protein HlyD K01993 - - 0.000000000000000000003971 109.0
HKD2_k127_2091441_36 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000007378 94.0
HKD2_k127_2091441_37 von Willebrand factor, type A - - - 0.00000000000008501 83.0
HKD2_k127_2091441_38 biopolymer transport protein K03559,K03560 - - 0.0000000000001119 76.0
HKD2_k127_2091441_39 phosphohydrolase (DHH superfamily) - - - 0.00006189 54.0
HKD2_k127_2091441_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 401.0
HKD2_k127_2091441_5 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 358.0
HKD2_k127_2091441_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 323.0
HKD2_k127_2091441_7 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 317.0
HKD2_k127_2091441_8 COG0788 Formyltetrahydrofolate hydrolase K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003771 291.0
HKD2_k127_2091441_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008208 271.0
HKD2_k127_21617_0 PEP-utilising enzyme, mobile domain - - - 0.0 1070.0
HKD2_k127_21617_1 Luciferase-like monooxygenase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 376.0
HKD2_k127_21617_2 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000007697 192.0
HKD2_k127_21617_4 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000005242 120.0
HKD2_k127_21617_5 AAA domain (dynein-related subfamily) - - - 0.000000000000000000003628 95.0
HKD2_k127_21617_6 Short repeat of unknown function (DUF308) - - - 0.000000000004604 74.0
HKD2_k127_216970_0 FAD binding domain K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 544.0
HKD2_k127_216970_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 522.0
HKD2_k127_216970_10 PFAM CBS domain K04767 - - 0.00000000000000000091 97.0
HKD2_k127_216970_11 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000001588 96.0
HKD2_k127_216970_12 Universal stress protein - - - 0.00000000000000001249 89.0
HKD2_k127_216970_13 Pfam Amidohydrolase - - - 0.0000000000001901 72.0
HKD2_k127_216970_14 Cytochrome c K02305,K07152 - - 0.0000000000002318 74.0
HKD2_k127_216970_15 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000006615 72.0
HKD2_k127_216970_16 ribosomal large subunit export from nucleus - - - 0.0000000008378 71.0
HKD2_k127_216970_17 PFAM heat shock protein DnaJ domain protein K05801 - - 0.00000006901 66.0
HKD2_k127_216970_18 Uncharacterized conserved protein (DUF2267) - - - 0.00000109 58.0
HKD2_k127_216970_2 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 482.0
HKD2_k127_216970_3 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 435.0
HKD2_k127_216970_4 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 307.0
HKD2_k127_216970_5 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005975 283.0
HKD2_k127_216970_6 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000007576 222.0
HKD2_k127_216970_7 - - - - 0.0000000000000000000000000000000000000000000000000002673 192.0
HKD2_k127_216970_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000001503 180.0
HKD2_k127_216970_9 Haem-binding domain - - - 0.000000000000000000000000000002127 127.0
HKD2_k127_2176445_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 GO:0000049,GO:0000166,GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004828,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006434,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0010467,GO:0016020,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046983,GO:0070905,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 519.0
HKD2_k127_2176445_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 359.0
HKD2_k127_2176445_2 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000002541 118.0
HKD2_k127_2176445_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000002537 82.0
HKD2_k127_2187540_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 458.0
HKD2_k127_2187540_1 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 469.0
HKD2_k127_2187540_2 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000004217 236.0
HKD2_k127_2187540_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000002715 135.0
HKD2_k127_2187540_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0007791 50.0
HKD2_k127_2216122_0 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000000004239 193.0
HKD2_k127_2216122_1 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000152 82.0
HKD2_k127_2216122_2 Trypsin-like serine protease K01312 - 3.4.21.4 0.00000000000791 78.0
HKD2_k127_2275151_0 PFAM carboxyl transferase K15052 - 2.1.3.15,6.4.1.3 2.943e-214 672.0
HKD2_k127_2275151_1 Biotin carboxylase K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 497.0
HKD2_k127_2508549_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 465.0
HKD2_k127_2508549_1 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000001616 224.0
HKD2_k127_2508549_2 - - - - 0.0000000000000000000000000003573 118.0
HKD2_k127_2562651_0 AcrB/AcrD/AcrF family K07787,K15726 - - 8.257e-299 947.0
HKD2_k127_2562651_1 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 306.0
HKD2_k127_2562651_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000318 184.0
HKD2_k127_2562651_3 Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.0000000000000000000000000000000000003742 151.0
HKD2_k127_2562651_4 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000009152 136.0
HKD2_k127_2562651_5 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000235 111.0
HKD2_k127_2583720_0 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 2.465e-194 622.0
HKD2_k127_2583720_1 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 516.0
HKD2_k127_2583720_10 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 305.0
HKD2_k127_2583720_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 310.0
HKD2_k127_2583720_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005531 277.0
HKD2_k127_2583720_13 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 256.0
HKD2_k127_2583720_14 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000005158 255.0
HKD2_k127_2583720_15 pfam abc K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000387 234.0
HKD2_k127_2583720_16 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005175 240.0
HKD2_k127_2583720_17 macromolecule localization K01421,K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000000000871 216.0
HKD2_k127_2583720_18 Hydrolase K17623 - 3.1.3.96 0.0000000000000000000000000000000000000000000000000000000003284 227.0
HKD2_k127_2583720_19 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.0000000000000000000000000000000000000000000000000000000006771 220.0
HKD2_k127_2583720_2 PFAM CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 449.0
HKD2_k127_2583720_20 S-acyltransferase activity K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000003685 219.0
HKD2_k127_2583720_21 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000007861 199.0
HKD2_k127_2583720_22 Luciferase-like monooxygenase K14728 - - 0.000000000000000000000000000000000000000000000000001034 206.0
HKD2_k127_2583720_23 GAF domain - - - 0.00000000000000000000000000000000000000000000000007014 200.0
HKD2_k127_2583720_24 domain, Protein - - - 0.0000000000000000000000000000000000000000000000005813 193.0
HKD2_k127_2583720_25 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000003758 155.0
HKD2_k127_2583720_27 phospholipase Carboxylesterase K06999 - - 0.0000000000000000000000000000002686 140.0
HKD2_k127_2583720_28 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000002397 124.0
HKD2_k127_2583720_29 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000004915 129.0
HKD2_k127_2583720_3 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 423.0
HKD2_k127_2583720_30 Kazal type serine protease inhibitors - - - 0.000000000000000000000000003747 125.0
HKD2_k127_2583720_31 Belongs to the ompA family K03286 - - 0.000000000000000000000006341 110.0
HKD2_k127_2583720_32 stress protein (general stress protein 26) - - - 0.00000000000000000000148 110.0
HKD2_k127_2583720_33 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000003564 85.0
HKD2_k127_2583720_34 Thioesterase superfamily - - - 0.00000000000000005235 86.0
HKD2_k127_2583720_35 YCII-related domain - - - 0.0000000000000002405 91.0
HKD2_k127_2583720_4 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 413.0
HKD2_k127_2583720_5 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 409.0
HKD2_k127_2583720_6 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 413.0
HKD2_k127_2583720_7 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 351.0
HKD2_k127_2583720_8 GMC oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 335.0
HKD2_k127_2583720_9 epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 327.0
HKD2_k127_2589917_0 Sulfatase K01130 - 3.1.6.1 0.0 1276.0
HKD2_k127_2589917_1 Mammalian cell entry K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 506.0
HKD2_k127_2589917_10 ABC-type transport auxiliary lipoprotein component K09857 - - 0.00000000000000000000000000000000000000000001688 178.0
HKD2_k127_2589917_11 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000002296 156.0
HKD2_k127_2589917_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000004346 130.0
HKD2_k127_2589917_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000002128 119.0
HKD2_k127_2589917_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000001335 116.0
HKD2_k127_2589917_15 - - - - 0.0000000000000000000000551 102.0
HKD2_k127_2589917_16 Ion channel - - - 0.000000000000000000006354 102.0
HKD2_k127_2589917_17 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000004159 89.0
HKD2_k127_2589917_18 long-chain fatty acid transport protein - - - 0.000000000000000614 93.0
HKD2_k127_2589917_19 - - - - 0.000000000000547 81.0
HKD2_k127_2589917_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 525.0
HKD2_k127_2589917_20 Phage tail tape measure protein TP901 - - - 0.0000006433 60.0
HKD2_k127_2589917_21 PA14 domain - GO:0005575,GO:0005576 - 0.00001262 49.0
HKD2_k127_2589917_22 Domain of unknown function (DUF4136) - - - 0.00009898 55.0
HKD2_k127_2589917_23 Amidase - - - 0.0009893 51.0
HKD2_k127_2589917_3 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 377.0
HKD2_k127_2589917_4 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 326.0
HKD2_k127_2589917_5 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000165 264.0
HKD2_k127_2589917_6 Paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000000000000000000001401 239.0
HKD2_k127_2589917_7 Transcriptional Regulator, AraC family - - - 0.0000000000000000000000000000000000000000000000000000007859 207.0
HKD2_k127_2589917_8 - - - - 0.000000000000000000000000000000000000000000000000000003246 203.0
HKD2_k127_2589917_9 - - - - 0.0000000000000000000000000000000000000000000000000001437 199.0
HKD2_k127_2592945_0 formate C-acetyltransferase glycine radical - - - 0.0 1169.0
HKD2_k127_2592945_1 AMP-binding enzyme - - - 1.82e-234 742.0
HKD2_k127_2592945_10 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003266 285.0
HKD2_k127_2592945_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 273.0
HKD2_k127_2592945_12 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000001882 209.0
HKD2_k127_2592945_13 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000000000002227 205.0
HKD2_k127_2592945_14 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000009647 168.0
HKD2_k127_2592945_15 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.00000000000000000000000000000000000006908 159.0
HKD2_k127_2592945_16 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000001952 148.0
HKD2_k127_2592945_17 AMP-binding enzyme C-terminal domain K04116 - - 0.00000000000000000000000000000000001645 138.0
HKD2_k127_2592945_18 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000002451 152.0
HKD2_k127_2592945_19 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000003353 139.0
HKD2_k127_2592945_2 MMPL family K06994 - - 2.94e-207 670.0
HKD2_k127_2592945_20 Fatty acid hydroxylase superfamily - - - 0.0000000000000000004248 100.0
HKD2_k127_2592945_21 MlaC protein K07323 - - 0.000000000000000005285 92.0
HKD2_k127_2592945_22 Major facilitator Superfamily - - - 0.000000000000002704 90.0
HKD2_k127_2592945_23 manganese ion transmembrane transporter activity - - - 0.0000000000003046 83.0
HKD2_k127_2592945_24 Nitrite and sulphite reductase 4Fe-4S K00176 - 1.2.7.3 0.0000009533 56.0
HKD2_k127_2592945_3 AMP-binding enzyme K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 629.0
HKD2_k127_2592945_4 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 484.0
HKD2_k127_2592945_5 DNA-binding response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 481.0
HKD2_k127_2592945_6 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 468.0
HKD2_k127_2592945_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 371.0
HKD2_k127_2592945_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 379.0
HKD2_k127_2592945_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 336.0
HKD2_k127_2620275_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 590.0
HKD2_k127_2620275_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 579.0
HKD2_k127_2620275_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000001664 211.0
HKD2_k127_2620275_11 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000004019 197.0
HKD2_k127_2620275_12 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000003128 142.0
HKD2_k127_2620275_13 ethyl tert-butyl ether degradation - - - 0.000000003465 70.0
HKD2_k127_2620275_14 Rhodanese-related sulfurtransferase - - - 0.00004552 50.0
HKD2_k127_2620275_2 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 574.0
HKD2_k127_2620275_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 489.0
HKD2_k127_2620275_4 Phosphate acyltransferases K15781 - 2.3.1.51,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 452.0
HKD2_k127_2620275_5 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 426.0
HKD2_k127_2620275_6 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 398.0
HKD2_k127_2620275_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004753 271.0
HKD2_k127_2620275_9 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000000000000004106 241.0
HKD2_k127_2620960_0 3-isopropylmalate dehydratase activity K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 9.544e-214 673.0
HKD2_k127_2620960_1 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 423.0
HKD2_k127_2620960_10 IMG reference gene - - - 0.000000000000000000000000000000000000000001851 175.0
HKD2_k127_2620960_11 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000003279 173.0
HKD2_k127_2620960_12 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000003867 179.0
HKD2_k127_2620960_13 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.000000000000000000000000000002652 136.0
HKD2_k127_2620960_14 PFAM peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000942 82.0
HKD2_k127_2620960_15 glycosyl transferase family K07151 - 2.4.99.18 0.000003368 61.0
HKD2_k127_2620960_16 PFAM Flp Fap pilin component K02651 - - 0.0005538 45.0
HKD2_k127_2620960_2 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 381.0
HKD2_k127_2620960_3 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 377.0
HKD2_k127_2620960_4 RecQ zinc-binding K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 348.0
HKD2_k127_2620960_5 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001005 299.0
HKD2_k127_2620960_6 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000003031 277.0
HKD2_k127_2620960_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000002992 232.0
HKD2_k127_2620960_8 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000001904 204.0
HKD2_k127_2620960_9 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000001721 198.0
HKD2_k127_2633380_1 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 483.0
HKD2_k127_2633380_10 iron ion binding - - - 0.00000000000000000000000000000000004953 140.0
HKD2_k127_2633380_11 ECF sigma factor K03088 - - 0.0000000000000000000000000006997 120.0
HKD2_k127_2633380_12 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000009098 113.0
HKD2_k127_2633380_13 pyridoxamine 5'-phosphate - - - 0.000000000000000283 93.0
HKD2_k127_2633380_14 Protein of unknown function (DUF1109) - - - 0.00000000003703 75.0
HKD2_k127_2633380_2 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 367.0
HKD2_k127_2633380_3 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 374.0
HKD2_k127_2633380_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 343.0
HKD2_k127_2633380_5 alpha beta - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 342.0
HKD2_k127_2633380_6 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 293.0
HKD2_k127_2633380_7 KR domain - GO:0003674,GO:0003824,GO:0004799,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008168,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016740,GO:0016741,GO:0019889,GO:0032259,GO:0033554,GO:0034599,GO:0042083,GO:0042221,GO:0042558,GO:0044237,GO:0046483,GO:0047040,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:1901360,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000006963 233.0
HKD2_k127_2633380_8 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000004571 243.0
HKD2_k127_2633380_9 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000004211 225.0
HKD2_k127_2652907_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00122 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 499.0
HKD2_k127_2652907_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 479.0
HKD2_k127_2652907_10 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 332.0
HKD2_k127_2652907_11 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 330.0
HKD2_k127_2652907_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002638 299.0
HKD2_k127_2652907_13 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009629 278.0
HKD2_k127_2652907_14 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001691 252.0
HKD2_k127_2652907_15 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000006641 187.0
HKD2_k127_2652907_16 KR domain - - - 0.000000000000000000000000000000000000000000000000007881 199.0
HKD2_k127_2652907_17 isochorismatase - - - 0.0000000000000000000000000000000000000000000000008624 181.0
HKD2_k127_2652907_18 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000002412 190.0
HKD2_k127_2652907_19 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000004589 168.0
HKD2_k127_2652907_2 Belongs to the aldehyde dehydrogenase family K00128,K00146 - 1.2.1.3,1.2.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 476.0
HKD2_k127_2652907_20 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000006493 151.0
HKD2_k127_2652907_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000001501 122.0
HKD2_k127_2652907_22 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000001212 111.0
HKD2_k127_2652907_23 - - - - 0.00000000000000000000002486 113.0
HKD2_k127_2652907_24 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000006958 97.0
HKD2_k127_2652907_25 Belongs to the peptidase S8 family - - - 0.00000003348 63.0
HKD2_k127_2652907_27 Pkd domain containing protein - - - 0.00007871 53.0
HKD2_k127_2652907_3 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 450.0
HKD2_k127_2652907_4 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 403.0
HKD2_k127_2652907_5 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 404.0
HKD2_k127_2652907_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 409.0
HKD2_k127_2652907_7 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 382.0
HKD2_k127_2652907_8 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 384.0
HKD2_k127_2652907_9 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 387.0
HKD2_k127_2655747_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 617.0
HKD2_k127_2655747_1 PAS domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 579.0
HKD2_k127_2655747_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 372.0
HKD2_k127_2655747_11 PFAM CorA-like Mg2 transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 358.0
HKD2_k127_2655747_12 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 340.0
HKD2_k127_2655747_13 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 324.0
HKD2_k127_2655747_14 His Kinase A (phosphoacceptor) domain K02484,K07636,K07768 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 323.0
HKD2_k127_2655747_15 Phosphate transport system permease protein PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 326.0
HKD2_k127_2655747_16 molybdate ABC transporter, inner membrane subunit K02017,K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 321.0
HKD2_k127_2655747_17 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 304.0
HKD2_k127_2655747_18 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 304.0
HKD2_k127_2655747_19 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001575 297.0
HKD2_k127_2655747_2 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 494.0
HKD2_k127_2655747_20 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003198 274.0
HKD2_k127_2655747_21 PFAM response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004925 257.0
HKD2_k127_2655747_22 NAD binding domain of 6-phosphogluconate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 257.0
HKD2_k127_2655747_23 General secretion pathway protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001322 257.0
HKD2_k127_2655747_24 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002713 258.0
HKD2_k127_2655747_25 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000002523 243.0
HKD2_k127_2655747_26 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.00000000000000000000000000000000000000000000000000000000000000006376 228.0
HKD2_k127_2655747_27 conserved protein (DUF2183) - - - 0.000000000000000000000000000000000000000000000000000000000003818 225.0
HKD2_k127_2655747_28 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002526 223.0
HKD2_k127_2655747_29 Molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000006489 213.0
HKD2_k127_2655747_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 453.0
HKD2_k127_2655747_30 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000008773 204.0
HKD2_k127_2655747_31 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000007712 195.0
HKD2_k127_2655747_32 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000007267 195.0
HKD2_k127_2655747_33 Zn peptidase - - - 0.00000000000000000000000000000000000000001908 174.0
HKD2_k127_2655747_34 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000001938 162.0
HKD2_k127_2655747_35 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000004428 156.0
HKD2_k127_2655747_36 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000374 155.0
HKD2_k127_2655747_37 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000001434 132.0
HKD2_k127_2655747_38 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000003137 128.0
HKD2_k127_2655747_39 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000005805 122.0
HKD2_k127_2655747_4 Cytochrome b(N-terminal)/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 428.0
HKD2_k127_2655747_40 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000004019 117.0
HKD2_k127_2655747_41 Putative porin - - - 0.00000000000000000000000002807 124.0
HKD2_k127_2655747_42 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000001938 118.0
HKD2_k127_2655747_43 Thioredoxin-like - - - 0.0000000000000000000002134 110.0
HKD2_k127_2655747_44 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000001611 104.0
HKD2_k127_2655747_45 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000002407 100.0
HKD2_k127_2655747_46 Protein of unknown function (DUF2905) - - - 0.000000000000000004715 90.0
HKD2_k127_2655747_47 PFAM glutaredoxin 2 - - - 0.00000000000001376 77.0
HKD2_k127_2655747_48 Type IV pilus assembly protein PilM; K02461 - - 0.00000001513 68.0
HKD2_k127_2655747_49 Type II transport protein GspH K08084 - - 0.00001801 51.0
HKD2_k127_2655747_5 GTP1/OBG K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 414.0
HKD2_k127_2655747_50 - - - - 0.00002103 59.0
HKD2_k127_2655747_51 synthase - - - 0.0002282 54.0
HKD2_k127_2655747_6 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 402.0
HKD2_k127_2655747_7 Belongs to the PstS family K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 398.0
HKD2_k127_2655747_8 TOBE domain K02017,K02018 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 380.0
HKD2_k127_2655747_9 Bacterial type II/III secretion system short domain K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 382.0
HKD2_k127_2667358_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005483 259.0
HKD2_k127_2667358_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000001906 244.0
HKD2_k127_2667358_2 Thioredoxin-like - - - 0.000000000000000000000000001703 118.0
HKD2_k127_2667358_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000008818 99.0
HKD2_k127_2667358_4 WD-40 repeat - - - 0.0000000002943 73.0
HKD2_k127_2667358_5 TIGRFAM 2-oxo-hepta-3-ene-1,7-dioic acid hydratase K02509 - - 0.000000001328 67.0
HKD2_k127_2667358_6 Cupredoxin-like domain - - - 0.00000004487 66.0
HKD2_k127_2667358_7 peptidyl-tyrosine sulfation - - - 0.00004516 53.0
HKD2_k127_2667358_8 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.0001619 53.0
HKD2_k127_2684836_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.165e-204 647.0
HKD2_k127_2684836_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 470.0
HKD2_k127_2684836_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.00000000000000000000000000000000000000000000000000000000000000000000001371 250.0
HKD2_k127_2684836_11 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000001207 250.0
HKD2_k127_2684836_12 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000009766 218.0
HKD2_k127_2684836_13 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000002118 199.0
HKD2_k127_2684836_14 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000005624 200.0
HKD2_k127_2684836_15 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000001244 134.0
HKD2_k127_2684836_16 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000002212 130.0
HKD2_k127_2684836_17 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000002767 137.0
HKD2_k127_2684836_18 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000001663 94.0
HKD2_k127_2684836_19 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000002571 80.0
HKD2_k127_2684836_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 433.0
HKD2_k127_2684836_20 TonB C terminal K03832 - - 0.000003687 59.0
HKD2_k127_2684836_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 334.0
HKD2_k127_2684836_4 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 329.0
HKD2_k127_2684836_5 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 318.0
HKD2_k127_2684836_6 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 296.0
HKD2_k127_2684836_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001382 291.0
HKD2_k127_2684836_8 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 277.0
HKD2_k127_2684836_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000002147 273.0
HKD2_k127_2686853_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 339.0
HKD2_k127_2686853_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 318.0
HKD2_k127_2686853_10 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000004008 217.0
HKD2_k127_2686853_11 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000007047 203.0
HKD2_k127_2686853_12 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000002512 195.0
HKD2_k127_2686853_13 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000002689 175.0
HKD2_k127_2686853_14 Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group K03635 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.00000000000000000000000000000000000005893 151.0
HKD2_k127_2686853_15 denitrification pathway K02569 - - 0.00000000000000000000000006376 117.0
HKD2_k127_2686853_16 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000000000009408 92.0
HKD2_k127_2686853_18 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000003064 60.0
HKD2_k127_2686853_19 - - - - 0.0000004787 63.0
HKD2_k127_2686853_2 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 302.0
HKD2_k127_2686853_20 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000001692 60.0
HKD2_k127_2686853_21 Cytochrome c - - - 0.0000168 51.0
HKD2_k127_2686853_3 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 293.0
HKD2_k127_2686853_4 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000209 304.0
HKD2_k127_2686853_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007644 295.0
HKD2_k127_2686853_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009077 293.0
HKD2_k127_2686853_7 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001669 266.0
HKD2_k127_2686853_8 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002097 265.0
HKD2_k127_2686853_9 Belongs to the enoyl-CoA hydratase isomerase family K01782,K07516 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000007212 252.0
HKD2_k127_270361_0 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 550.0
HKD2_k127_270361_1 Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000001158 59.0
HKD2_k127_2762025_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 483.0
HKD2_k127_2762025_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 428.0
HKD2_k127_2762025_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 337.0
HKD2_k127_2762369_0 protein involved in exopolysaccharide biosynthesis K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 322.0
HKD2_k127_2762369_1 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 268.0
HKD2_k127_2762369_2 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000008314 241.0
HKD2_k127_2762369_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000003198 145.0
HKD2_k127_2762369_4 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000009096 139.0
HKD2_k127_2762369_5 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000005468 133.0
HKD2_k127_2762369_6 PFAM Polysaccharide export protein K01991 - - 0.0000000000000000000000001459 120.0
HKD2_k127_2767661_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 568.0
HKD2_k127_2767661_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 388.0
HKD2_k127_2767661_2 PFAM ABC transporter related K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000009052 239.0
HKD2_k127_2767661_3 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000006458 213.0
HKD2_k127_2767661_4 QueT transporter K16928 - - 0.000000000000000000000000000000000000000000000000000001363 200.0
HKD2_k127_2767661_5 ThiS family K03636 - - 0.00000000000000000000000000000009122 126.0
HKD2_k127_2767661_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000003527 119.0
HKD2_k127_2767661_7 methionine transport K02071 - - 0.000000000000002253 89.0
HKD2_k127_2767661_8 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.000000492 59.0
HKD2_k127_2776347_0 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 438.0
HKD2_k127_2776347_1 Domain of unknown function (DUF1998) K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 296.0
HKD2_k127_2776347_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000001568 64.0
HKD2_k127_2783028_0 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001138 248.0
HKD2_k127_2783028_1 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000000008037 157.0
HKD2_k127_2816593_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1440.0
HKD2_k127_2816593_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.084e-200 654.0
HKD2_k127_2816593_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 502.0
HKD2_k127_2816593_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 487.0
HKD2_k127_2816593_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 447.0
HKD2_k127_2816593_5 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 432.0
HKD2_k127_2816593_6 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 406.0
HKD2_k127_2816593_7 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004516 284.0
HKD2_k127_2816593_8 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000395 230.0
HKD2_k127_2845972_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.063e-267 842.0
HKD2_k127_2845972_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 1.611e-195 635.0
HKD2_k127_2845972_10 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 321.0
HKD2_k127_2845972_11 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 305.0
HKD2_k127_2845972_12 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 304.0
HKD2_k127_2845972_13 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 302.0
HKD2_k127_2845972_14 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 293.0
HKD2_k127_2845972_15 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 291.0
HKD2_k127_2845972_16 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007948 274.0
HKD2_k127_2845972_17 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001336 272.0
HKD2_k127_2845972_18 acyl-CoA hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006858 263.0
HKD2_k127_2845972_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000006014 222.0
HKD2_k127_2845972_2 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 615.0
HKD2_k127_2845972_20 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000004106 208.0
HKD2_k127_2845972_21 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000006589 193.0
HKD2_k127_2845972_22 Metallophosphoesterase, calcineurin superfamily - - - 0.0000000000000000000000000000000000000000000000001751 184.0
HKD2_k127_2845972_23 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000003057 172.0
HKD2_k127_2845972_24 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.000000000000000000000000000000002936 134.0
HKD2_k127_2845972_25 - - - - 0.00000000000000000000000000000008921 141.0
HKD2_k127_2845972_26 Platelet-activating factor acetylhydrolase, isoform II - - - 0.0000000000000000000000000000001301 141.0
HKD2_k127_2845972_27 Protein of unknown function (DUF3574) - - - 0.00000000000000000000003201 115.0
HKD2_k127_2845972_28 THUMP - - - 0.00000000000000000000107 112.0
HKD2_k127_2845972_29 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.000000000000000000003211 106.0
HKD2_k127_2845972_3 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 439.0
HKD2_k127_2845972_30 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.000000000001548 70.0
HKD2_k127_2845972_32 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001604 68.0
HKD2_k127_2845972_33 Domain of unknown function (DUF4911) - - - 0.00000008388 60.0
HKD2_k127_2845972_34 Acetyltransferase (GNAT) family - - - 0.00004694 57.0
HKD2_k127_2845972_4 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 407.0
HKD2_k127_2845972_5 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 386.0
HKD2_k127_2845972_6 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 352.0
HKD2_k127_2845972_7 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 365.0
HKD2_k127_2845972_8 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 329.0
HKD2_k127_2845972_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 316.0
HKD2_k127_287638_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00249 - 1.3.8.7 1.011e-215 675.0
HKD2_k127_287638_1 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 632.0
HKD2_k127_287638_10 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001167 275.0
HKD2_k127_287638_11 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003741 281.0
HKD2_k127_287638_12 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001864 263.0
HKD2_k127_287638_13 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000412 218.0
HKD2_k127_287638_14 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000003157 188.0
HKD2_k127_287638_15 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.0000000000000000000000000000000000000000000000008523 202.0
HKD2_k127_287638_16 PFAM Glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000001655 171.0
HKD2_k127_287638_17 - - - - 0.000000000000000000000000000000000000003518 160.0
HKD2_k127_287638_18 Iron-binding zinc finger CDGSH type - - - 0.0000000000000001699 81.0
HKD2_k127_287638_19 CopC domain K07156 - - 0.0000000000000582 77.0
HKD2_k127_287638_2 Biotin carboxylase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 509.0
HKD2_k127_287638_20 3D domain - - - 0.0000000000002784 78.0
HKD2_k127_287638_21 Protein of unknown function (DUF1329) - - - 0.0000000000004602 83.0
HKD2_k127_287638_22 Cysteine rich repeat K06816 GO:0000137,GO:0000138,GO:0000139,GO:0001501,GO:0002376,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005797,GO:0005886,GO:0006810,GO:0006886,GO:0006928,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009887,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010955,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016477,GO:0017015,GO:0017134,GO:0019222,GO:0019838,GO:0023051,GO:0023057,GO:0030162,GO:0030512,GO:0031012,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031984,GO:0031985,GO:0032268,GO:0032269,GO:0032330,GO:0032501,GO:0032502,GO:0033036,GO:0034613,GO:0040011,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045861,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050900,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051641,GO:0051649,GO:0051674,GO:0060255,GO:0060348,GO:0060349,GO:0061035,GO:0065007,GO:0070613,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0080090,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0098588,GO:0098791,GO:1903317,GO:1903318,GO:1903844,GO:1903845,GO:2000026 - 0.000000000003776 72.0
HKD2_k127_287638_24 Bacterial regulatory proteins, tetR family - - - 0.000004082 56.0
HKD2_k127_287638_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 435.0
HKD2_k127_287638_4 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 405.0
HKD2_k127_287638_5 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 406.0
HKD2_k127_287638_6 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 382.0
HKD2_k127_287638_7 Copper resistance K07245 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 357.0
HKD2_k127_287638_8 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 347.0
HKD2_k127_287638_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 293.0
HKD2_k127_2904880_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.259e-284 895.0
HKD2_k127_2904880_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 582.0
HKD2_k127_2904880_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001965 285.0
HKD2_k127_2904880_3 response regulator - - - 0.000000000000000000000000000000000000000000000006722 191.0
HKD2_k127_2904880_4 Histidine kinase - - - 0.00000000000000000000000001921 120.0
HKD2_k127_2904880_5 nitrous-oxide reductase activity - - - 0.00000000000003057 80.0
HKD2_k127_2908623_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 604.0
HKD2_k127_2908623_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 554.0
HKD2_k127_2908623_10 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000003726 210.0
HKD2_k127_2908623_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000008185 154.0
HKD2_k127_2908623_12 aspartic-type endopeptidase activity - - - 0.00000000000000000000000000000000000429 144.0
HKD2_k127_2908623_13 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000003025 123.0
HKD2_k127_2908623_14 Protein of unknown function, DUF393 - - - 0.000000000000000000000759 104.0
HKD2_k127_2908623_15 deaminase - - - 0.0000000000000000000223 98.0
HKD2_k127_2908623_16 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000009056 98.0
HKD2_k127_2908623_17 Protein involved in outer membrane biogenesis K07289 - - 0.0000008455 62.0
HKD2_k127_2908623_18 Histidine kinase - - - 0.00001987 55.0
HKD2_k127_2908623_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 494.0
HKD2_k127_2908623_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009011 474.0
HKD2_k127_2908623_4 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 411.0
HKD2_k127_2908623_5 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
HKD2_k127_2908623_6 YD repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 375.0
HKD2_k127_2908623_7 Major royal jelly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 316.0
HKD2_k127_2908623_8 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006147 293.0
HKD2_k127_2908623_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002469 244.0
HKD2_k127_2997548_0 Protein of unknown function (DUF3604) - - - 4.328e-232 739.0
HKD2_k127_2997548_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 374.0
HKD2_k127_2997548_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005871 285.0
HKD2_k127_2997548_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006939 263.0
HKD2_k127_2997548_4 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000007884 220.0
HKD2_k127_2997548_5 PPIC-type PPIASE domain - - - 0.000000000000000000000000000006095 134.0
HKD2_k127_2997548_6 Outer membrane lipoprotein-sorting protein - - - 0.0004719 48.0
HKD2_k127_3044771_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 387.0
HKD2_k127_3044771_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 370.0
HKD2_k127_3044771_10 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000005426 128.0
HKD2_k127_3044771_11 Trehalose utilisation - - - 0.000000002612 66.0
HKD2_k127_3044771_12 General secretion pathway protein K02453 - - 0.0000002007 55.0
HKD2_k127_3044771_2 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 306.0
HKD2_k127_3044771_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000001282 247.0
HKD2_k127_3044771_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000003358 231.0
HKD2_k127_3044771_5 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000007111 166.0
HKD2_k127_3044771_6 PFAM peptidase M6, immune inhibitor A - - - 0.00000000000000000000000000000000000003341 162.0
HKD2_k127_3044771_7 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000005562 158.0
HKD2_k127_3044771_8 4Fe-4S binding domain - - - 0.000000000000000000000000000000005571 144.0
HKD2_k127_3044771_9 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000004883 119.0
HKD2_k127_3062797_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.283e-275 856.0
HKD2_k127_3062797_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.226e-212 692.0
HKD2_k127_3062797_10 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 420.0
HKD2_k127_3062797_11 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 407.0
HKD2_k127_3062797_12 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 379.0
HKD2_k127_3062797_13 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 377.0
HKD2_k127_3062797_14 TIGRFAM peptidase T-like protein K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 342.0
HKD2_k127_3062797_15 Protein of unknown function, DUF255 K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 309.0
HKD2_k127_3062797_16 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 304.0
HKD2_k127_3062797_17 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002108 288.0
HKD2_k127_3062797_18 archaeal or bacterial-type flagellum-dependent cell motility K02556 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001906 262.0
HKD2_k127_3062797_19 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000732 264.0
HKD2_k127_3062797_2 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 8.231e-200 641.0
HKD2_k127_3062797_20 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000008167 258.0
HKD2_k127_3062797_21 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000002974 236.0
HKD2_k127_3062797_22 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000001133 221.0
HKD2_k127_3062797_23 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000004507 221.0
HKD2_k127_3062797_24 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000008431 211.0
HKD2_k127_3062797_25 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000001367 205.0
HKD2_k127_3062797_26 Sulfopyruvate decarboxylase K06034,K09459 - 4.1.1.79,4.1.1.82 0.000000000000000000000000000000000000000001186 163.0
HKD2_k127_3062797_27 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.0000000000000000000000000000000000000001211 156.0
HKD2_k127_3062797_28 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000004296 159.0
HKD2_k127_3062797_29 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000004841 138.0
HKD2_k127_3062797_3 Acetyl-CoA hydrolase/transferase C-terminal domain K18288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 572.0
HKD2_k127_3062797_30 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000001344 125.0
HKD2_k127_3062797_31 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.000000000000000000000001953 108.0
HKD2_k127_3062797_32 PHP-associated - - - 0.000000000000000000000009764 109.0
HKD2_k127_3062797_33 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000003663 114.0
HKD2_k127_3062797_34 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000007454 107.0
HKD2_k127_3062797_35 Zincin-like metallopeptidase - - - 0.000000000000001123 91.0
HKD2_k127_3062797_36 N-terminal half of MaoC dehydratase - - - 0.00000000003246 72.0
HKD2_k127_3062797_37 DNA-binding response regulator K07713 - - 0.00000000004973 68.0
HKD2_k127_3062797_38 N-terminal half of MaoC dehydratase - - - 0.0000002485 59.0
HKD2_k127_3062797_39 Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor K00226 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006106,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019752,GO:0019856,GO:0020015,GO:0034641,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.1 0.0000004955 62.0
HKD2_k127_3062797_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 537.0
HKD2_k127_3062797_40 Redoxin - - - 0.0000006085 55.0
HKD2_k127_3062797_41 Domain of unknown function (DUF4345) - - - 0.0006585 52.0
HKD2_k127_3062797_5 TIGRFAM phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 522.0
HKD2_k127_3062797_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 467.0
HKD2_k127_3062797_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 449.0
HKD2_k127_3062797_8 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 428.0
HKD2_k127_3062797_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 425.0
HKD2_k127_3113924_0 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.0 1135.0
HKD2_k127_3113924_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.114e-275 881.0
HKD2_k127_3113924_10 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 314.0
HKD2_k127_3113924_11 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000002506 227.0
HKD2_k127_3113924_12 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000001006 210.0
HKD2_k127_3113924_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000001068 200.0
HKD2_k127_3113924_14 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000005394 154.0
HKD2_k127_3113924_15 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000009356 128.0
HKD2_k127_3113924_16 Voltage gated chloride channel K03281 - - 0.000000000000000000000000001326 121.0
HKD2_k127_3113924_17 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000001622 113.0
HKD2_k127_3113924_18 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000006122 105.0
HKD2_k127_3113924_19 peptidyl-tyrosine sulfation - - - 0.000000000000143 79.0
HKD2_k127_3113924_2 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 6.064e-248 789.0
HKD2_k127_3113924_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000009061 58.0
HKD2_k127_3113924_3 glycyl-tRNA aminoacylation K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 601.0
HKD2_k127_3113924_4 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 417.0
HKD2_k127_3113924_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 409.0
HKD2_k127_3113924_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 395.0
HKD2_k127_3113924_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 353.0
HKD2_k127_3113924_8 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 346.0
HKD2_k127_3113924_9 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 343.0
HKD2_k127_3136357_0 Glycosyl transferase, family 2 - - - 4.159e-296 934.0
HKD2_k127_3136357_1 PFAM ABC transporter, transmembrane region K06147,K11085 - - 1.751e-206 662.0
HKD2_k127_3136357_10 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004793 283.0
HKD2_k127_3136357_11 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000001109 246.0
HKD2_k127_3136357_12 RNA pseudouridylate synthase K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000001296 227.0
HKD2_k127_3136357_13 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000001245 219.0
HKD2_k127_3136357_14 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000001142 207.0
HKD2_k127_3136357_15 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000002986 206.0
HKD2_k127_3136357_16 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000008297 205.0
HKD2_k127_3136357_17 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000005205 186.0
HKD2_k127_3136357_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000002188 180.0
HKD2_k127_3136357_19 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000001595 174.0
HKD2_k127_3136357_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 614.0
HKD2_k127_3136357_20 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000009869 135.0
HKD2_k127_3136357_21 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000002745 131.0
HKD2_k127_3136357_22 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000001875 138.0
HKD2_k127_3136357_23 cheY-homologous receiver domain - - - 0.000000000000000000000000000005284 124.0
HKD2_k127_3136357_24 - - - - 0.0002207 45.0
HKD2_k127_3136357_25 - - - - 0.0002902 47.0
HKD2_k127_3136357_3 DNA-binding response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 494.0
HKD2_k127_3136357_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 452.0
HKD2_k127_3136357_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 432.0
HKD2_k127_3136357_6 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 403.0
HKD2_k127_3136357_7 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 374.0
HKD2_k127_3136357_8 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 337.0
HKD2_k127_3136357_9 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 328.0
HKD2_k127_3195838_0 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 537.0
HKD2_k127_3195838_1 Peptidase, M20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 456.0
HKD2_k127_3195838_10 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 322.0
HKD2_k127_3195838_11 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 319.0
HKD2_k127_3195838_12 Acyl-CoA synthetase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005394 296.0
HKD2_k127_3195838_13 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001061 297.0
HKD2_k127_3195838_14 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
HKD2_k127_3195838_15 Enoyl-coA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005397 250.0
HKD2_k127_3195838_16 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000789 250.0
HKD2_k127_3195838_17 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001526 248.0
HKD2_k127_3195838_18 FMN reductase (NADPH) activity - - - 0.0000000000000000000000000000000000000000000000000000000203 202.0
HKD2_k127_3195838_19 COG3119 Arylsulfatase A and related enzymes K01130,K01133 - 3.1.6.1,3.1.6.6 0.0000000000000000000000000000000000000000000000000000000255 219.0
HKD2_k127_3195838_2 oxidoreductases (related to aryl-alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 432.0
HKD2_k127_3195838_20 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000002624 205.0
HKD2_k127_3195838_21 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000005682 204.0
HKD2_k127_3195838_22 KR domain K07124 - - 0.0000000000000000000000000000000000002208 153.0
HKD2_k127_3195838_23 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000005803 132.0
HKD2_k127_3195838_24 Transport and Golgi organisation 2 - - - 0.000000000000000000006588 103.0
HKD2_k127_3195838_25 domain, Protein K02574 - - 0.000000000000009447 85.0
HKD2_k127_3195838_26 regulator of chromosome condensation, RCC1 - - - 0.00000000000007101 86.0
HKD2_k127_3195838_27 nucleoside hydrolase - - - 0.00000000001228 79.0
HKD2_k127_3195838_28 MaoC like domain - - - 0.00000009878 65.0
HKD2_k127_3195838_29 - - GO:0000003,GO:0003006,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0007275,GO:0008150,GO:0009553,GO:0009554,GO:0009987,GO:0016020,GO:0019953,GO:0022402,GO:0022414,GO:0031224,GO:0031225,GO:0032501,GO:0032502,GO:0034293,GO:0043934,GO:0044425,GO:0044464,GO:0044703,GO:0048229,GO:0048236,GO:0048856,GO:0048869,GO:0051321,GO:0051704,GO:0071944,GO:1903046 - 0.000002063 58.0
HKD2_k127_3195838_3 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 345.0
HKD2_k127_3195838_30 SnoaL-like domain - - - 0.00000415 51.0
HKD2_k127_3195838_4 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 342.0
HKD2_k127_3195838_5 Inositol monophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 344.0
HKD2_k127_3195838_6 Haloalkane dehalogenase K01563 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 332.0
HKD2_k127_3195838_7 cytochrome p450 K17474 - 1.14.15.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 334.0
HKD2_k127_3195838_8 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 333.0
HKD2_k127_3195838_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 326.0
HKD2_k127_3209389_0 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 267.0
HKD2_k127_3209389_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005357 257.0
HKD2_k127_3209389_2 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000205 213.0
HKD2_k127_3209389_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000007192 96.0
HKD2_k127_3209389_4 lysyltransferase activity K07027 - - 0.000000000000241 82.0
HKD2_k127_3209389_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K21781 GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 - 0.000002145 55.0
HKD2_k127_3209389_7 START domain - - - 0.0001516 54.0
HKD2_k127_3209389_8 sequence-specific DNA binding - - - 0.0003978 48.0
HKD2_k127_3209389_9 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0004812 53.0
HKD2_k127_321654_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 523.0
HKD2_k127_321654_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 500.0
HKD2_k127_321654_10 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 321.0
HKD2_k127_321654_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 301.0
HKD2_k127_321654_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000285 270.0
HKD2_k127_321654_13 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000006154 233.0
HKD2_k127_321654_14 PFAM Anion-transporting ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000001083 235.0
HKD2_k127_321654_15 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000004621 166.0
HKD2_k127_321654_16 Anion-transporting ATPase - - - 0.0000000000000000000000000000000000002053 155.0
HKD2_k127_321654_17 MlaC protein K07323 - - 0.000000000000000000000000000000005963 139.0
HKD2_k127_321654_18 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000003354 122.0
HKD2_k127_321654_19 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000003947 114.0
HKD2_k127_321654_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 471.0
HKD2_k127_321654_20 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000002794 109.0
HKD2_k127_321654_21 F420H(2)-dependent quinone reductase - GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0030312,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363 - 0.00000000000000000002115 99.0
HKD2_k127_321654_22 Essential cell division protein K03589 - - 0.0000000000003482 83.0
HKD2_k127_321654_23 - - - - 0.000000002054 65.0
HKD2_k127_321654_25 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000009069 47.0
HKD2_k127_321654_26 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.0006042 51.0
HKD2_k127_321654_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 464.0
HKD2_k127_321654_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 445.0
HKD2_k127_321654_5 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 449.0
HKD2_k127_321654_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 412.0
HKD2_k127_321654_7 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 347.0
HKD2_k127_321654_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 359.0
HKD2_k127_321654_9 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 343.0
HKD2_k127_3345827_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 445.0
HKD2_k127_3345827_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 333.0
HKD2_k127_3345827_2 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000008464 78.0
HKD2_k127_349079_0 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 582.0
HKD2_k127_349079_1 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 538.0
HKD2_k127_349079_10 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007521 258.0
HKD2_k127_349079_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000001832 235.0
HKD2_k127_349079_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000004916 253.0
HKD2_k127_349079_13 transcriptional regulator - - - 0.000000000000000000000000000000000000000004443 171.0
HKD2_k127_349079_14 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000605 158.0
HKD2_k127_349079_15 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000003481 143.0
HKD2_k127_349079_16 FG-GAP repeat - - - 0.000000000000000000000000000000004312 150.0
HKD2_k127_349079_17 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000005482 144.0
HKD2_k127_349079_18 Protein of unknown function (DUF420) K08976 - - 0.0000000000000000000000000000009379 136.0
HKD2_k127_349079_19 ArsC family - - - 0.00000000000000000000000000003172 128.0
HKD2_k127_349079_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 504.0
HKD2_k127_349079_20 CHAT domain - - - 0.000000000000000000000007247 118.0
HKD2_k127_349079_21 CYTH K01768,K05873 - 4.6.1.1 0.00000000000000000000008367 113.0
HKD2_k127_349079_22 AIG2-like family - - - 0.0000000000000001199 92.0
HKD2_k127_349079_23 - - - - 0.00000000000001392 88.0
HKD2_k127_349079_24 - - - - 0.000000000001601 81.0
HKD2_k127_349079_25 Helix-turn-helix domain - - - 0.00000002231 62.0
HKD2_k127_349079_26 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.00000009648 66.0
HKD2_k127_349079_27 - - - - 0.0000006807 63.0
HKD2_k127_349079_28 Pfam:DUF385 - - - 0.00004261 56.0
HKD2_k127_349079_29 ECF sigma factor K03088 - - 0.000297 51.0
HKD2_k127_349079_3 Belongs to the aldehyde dehydrogenase family K00135,K22445 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 447.0
HKD2_k127_349079_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 364.0
HKD2_k127_349079_5 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 311.0
HKD2_k127_349079_6 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 305.0
HKD2_k127_349079_7 Mate efflux family protein K03327 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006862,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015215,GO:0015230,GO:0015605,GO:0015711,GO:0015748,GO:0015833,GO:0015931,GO:0015932,GO:0016020,GO:0022857,GO:0034220,GO:0035350,GO:0035442,GO:0035672,GO:0035673,GO:0042886,GO:0042887,GO:0042938,GO:0044464,GO:0044610,GO:0051179,GO:0051181,GO:0051182,GO:0051184,GO:0051185,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071916,GO:0071944,GO:0098656,GO:1901264,GO:1901505,GO:1901679,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006723 269.0
HKD2_k127_349079_8 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004503 241.0
HKD2_k127_349079_9 Alpha/beta hydrolase family K18092 - - 0.0000000000000000000000000000000000000000000000000000000000000000005985 238.0
HKD2_k127_350070_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 9.495e-219 708.0
HKD2_k127_350070_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.815e-196 633.0
HKD2_k127_350070_10 KR domain K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000179 278.0
HKD2_k127_350070_11 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001007 268.0
HKD2_k127_350070_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002506 253.0
HKD2_k127_350070_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941,K18824 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000003462 266.0
HKD2_k127_350070_14 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000001009 224.0
HKD2_k127_350070_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000002987 211.0
HKD2_k127_350070_16 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000001685 194.0
HKD2_k127_350070_17 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000221 162.0
HKD2_k127_350070_18 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000000000009223 147.0
HKD2_k127_350070_19 PFAM NUDIX domain - - - 0.0000000000000000000000000000000515 130.0
HKD2_k127_350070_2 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 548.0
HKD2_k127_350070_20 - - - - 0.0000000000000000000000000001504 118.0
HKD2_k127_350070_21 Protein of unknown function (DUF1329) - - - 0.000000000000000000000188 112.0
HKD2_k127_350070_22 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000002174 103.0
HKD2_k127_350070_23 CarboxypepD_reg-like domain - - - 0.0000000000000000001893 102.0
HKD2_k127_350070_25 FeoA K04758 - - 0.0000000001115 72.0
HKD2_k127_350070_26 Dodecin K09165 - - 0.0001277 49.0
HKD2_k127_350070_3 AMP-binding enzyme C-terminal domain K04116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 459.0
HKD2_k127_350070_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 429.0
HKD2_k127_350070_5 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 411.0
HKD2_k127_350070_6 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 388.0
HKD2_k127_350070_7 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 387.0
HKD2_k127_350070_8 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 327.0
HKD2_k127_350070_9 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 329.0
HKD2_k127_3624882_0 PFAM ABC transporter K02471 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 383.0
HKD2_k127_3624882_1 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000957 46.0
HKD2_k127_3813199_0 PFAM Glycoside hydrolase, family 38 K01191,K15524 - 3.2.1.170,3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 424.0
HKD2_k127_3813199_1 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000005354 221.0
HKD2_k127_3813199_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001138 175.0
HKD2_k127_3813199_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000004401 112.0
HKD2_k127_3831237_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1030.0
HKD2_k127_3831237_1 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.2 2.792e-229 718.0
HKD2_k127_3831237_10 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000004167 189.0
HKD2_k127_3831237_11 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000005104 189.0
HKD2_k127_3831237_12 KR domain - - - 0.000000000000000000000000000000000000000000000001766 184.0
HKD2_k127_3831237_13 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000000000001761 158.0
HKD2_k127_3831237_14 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.00000000000000000000000000000004729 139.0
HKD2_k127_3831237_15 Lysyl oxidase - - - 0.00000000000000000000000000000006879 144.0
HKD2_k127_3831237_16 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000009084 132.0
HKD2_k127_3831237_17 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000003775 140.0
HKD2_k127_3831237_18 glyoxalase III activity - - - 0.00000000000000000000000000009814 129.0
HKD2_k127_3831237_19 transcriptional regulator - - - 0.0000000000000002142 87.0
HKD2_k127_3831237_2 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 521.0
HKD2_k127_3831237_20 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000005221 88.0
HKD2_k127_3831237_21 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000001043 74.0
HKD2_k127_3831237_22 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000001906 74.0
HKD2_k127_3831237_23 sequence-specific DNA binding K07726 - - 0.0000001056 61.0
HKD2_k127_3831237_24 TPR repeat - - - 0.0000004511 62.0
HKD2_k127_3831237_25 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.00009548 55.0
HKD2_k127_3831237_26 Cell envelope-related transcriptional attenuator domain - - - 0.0004928 51.0
HKD2_k127_3831237_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 340.0
HKD2_k127_3831237_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 326.0
HKD2_k127_3831237_5 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 319.0
HKD2_k127_3831237_6 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006337 274.0
HKD2_k127_3831237_7 Peptidase family C69 K14358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000607 283.0
HKD2_k127_3831237_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000389 249.0
HKD2_k127_3831237_9 Smr domain - - - 0.0000000000000000000000000000000000000000000000000000001463 203.0
HKD2_k127_3844538_0 acyl-CoA dehydrogenase - - - 4.401e-213 679.0
HKD2_k127_3844538_1 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 503.0
HKD2_k127_3844538_10 SnoaL-like domain - - - 0.0000000000000000000000000000000000000005318 154.0
HKD2_k127_3844538_11 Lipase maturation factor - - - 0.00000000000000000000000000000000001712 141.0
HKD2_k127_3844538_12 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.00000000000000000000000000002271 128.0
HKD2_k127_3844538_13 COG0501 Zn-dependent protease with chaperone function - - - 0.0000000006043 71.0
HKD2_k127_3844538_14 Pfam:Pyridox_oxidase - - - 0.00003515 52.0
HKD2_k127_3844538_2 rieske 2Fe-2S domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 426.0
HKD2_k127_3844538_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 360.0
HKD2_k127_3844538_4 acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 352.0
HKD2_k127_3844538_5 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 309.0
HKD2_k127_3844538_6 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000002571 262.0
HKD2_k127_3844538_7 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003011 243.0
HKD2_k127_3844538_8 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000004241 250.0
HKD2_k127_3844538_9 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000001948 198.0
HKD2_k127_3854580_0 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847,K14447 - 5.4.99.2,5.4.99.63 2.023e-307 954.0
HKD2_k127_3854580_1 LAO AO transport system K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 386.0
HKD2_k127_3854580_10 - - - - 0.00000000000000000000001229 105.0
HKD2_k127_3854580_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000443 83.0
HKD2_k127_3854580_12 KR domain - - - 0.000000000000001437 80.0
HKD2_k127_3854580_2 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 390.0
HKD2_k127_3854580_3 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 372.0
HKD2_k127_3854580_4 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000001811 226.0
HKD2_k127_3854580_5 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000006437 212.0
HKD2_k127_3854580_6 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000007276 214.0
HKD2_k127_3854580_7 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000008548 192.0
HKD2_k127_3854580_8 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000003546 157.0
HKD2_k127_3854580_9 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000001456 137.0
HKD2_k127_3860167_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 345.0
HKD2_k127_3860167_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 308.0
HKD2_k127_3860167_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000002531 221.0
HKD2_k127_3860167_3 transcriptional regulator - - - 0.000000000000002284 84.0
HKD2_k127_3861653_0 DNA polymerase type-B family K02336 - 2.7.7.7 1.381e-301 947.0
HKD2_k127_3861653_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 545.0
HKD2_k127_3861653_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 410.0
HKD2_k127_3861653_3 Transcriptional regulator K12146,K15836 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001150,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016043,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0022607,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0042802,GO:0043170,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2000144,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 384.0
HKD2_k127_3861653_4 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 367.0
HKD2_k127_3861653_5 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 342.0
HKD2_k127_3861653_6 pyridoxamine 5-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006857 282.0
HKD2_k127_3861653_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005745 289.0
HKD2_k127_3861653_8 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000002274 141.0
HKD2_k127_3861653_9 Sensory box protein response regulator - - - 0.0000000000000000005426 96.0
HKD2_k127_3873954_0 Flavoprotein involved in K transport - - - 1.058e-254 794.0
HKD2_k127_3873954_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 416.0
HKD2_k127_3873954_2 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 343.0
HKD2_k127_3873954_3 pyridine nucleotide-disulphide oxidoreductase - GO:0003674,GO:0003824,GO:0005575,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016782,GO:0031224,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0044425,GO:0046505,GO:0046506,GO:0071704,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 331.0
HKD2_k127_3873954_4 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 320.0
HKD2_k127_3873954_6 peptidase inhibitor activity K19919,K20412 GO:0006950,GO:0007275,GO:0007568,GO:0008150,GO:0008340,GO:0009266,GO:0009314,GO:0009408,GO:0009411,GO:0009416,GO:0009628,GO:0010259,GO:0032501,GO:0032502,GO:0048856,GO:0050896 - 0.000000000000000000000000004673 119.0
HKD2_k127_3873954_8 Right handed beta helix region - - - 0.00004795 57.0
HKD2_k127_3885696_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.694e-275 858.0
HKD2_k127_3885696_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 7.282e-202 643.0
HKD2_k127_3885696_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075,K15780 - 2.4.2.8,6.3.4.19 0.000000000000000000000000000000000000000000000000000001553 208.0
HKD2_k127_3885696_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000003875 191.0
HKD2_k127_3885696_12 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000002562 138.0
HKD2_k127_3885696_13 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000008121 129.0
HKD2_k127_3885696_14 PFAM YbbR family protein - - - 0.000000000000363 84.0
HKD2_k127_3885696_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 578.0
HKD2_k127_3885696_3 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 499.0
HKD2_k127_3885696_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 409.0
HKD2_k127_3885696_5 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 365.0
HKD2_k127_3885696_6 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 333.0
HKD2_k127_3885696_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 316.0
HKD2_k127_3885696_8 KH domain K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006668 281.0
HKD2_k127_3885696_9 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000003604 243.0
HKD2_k127_3895398_0 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 437.0
HKD2_k127_3895398_1 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 416.0
HKD2_k127_3895398_10 Rhomboid family - - - 0.000000000000000000000000000000000000006741 160.0
HKD2_k127_3895398_11 Pantothenate kinase K09680 - 2.7.1.33 0.00000000000000000000000000005687 129.0
HKD2_k127_3895398_12 Bacterial regulatory proteins, tetR family - - - 0.000000000000004274 86.0
HKD2_k127_3895398_13 Belongs to the UPF0270 family K09898 - - 0.00000000005042 70.0
HKD2_k127_3895398_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 353.0
HKD2_k127_3895398_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 350.0
HKD2_k127_3895398_4 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000001217 235.0
HKD2_k127_3895398_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000009125 212.0
HKD2_k127_3895398_6 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000002183 203.0
HKD2_k127_3895398_7 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000003248 221.0
HKD2_k127_3895398_8 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000001458 206.0
HKD2_k127_3895398_9 Amidohydrolase - - - 0.000000000000000000000000000000000000000006285 170.0
HKD2_k127_3906225_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.309e-252 786.0
HKD2_k127_3906225_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00122 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 604.0
HKD2_k127_3906225_10 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 327.0
HKD2_k127_3906225_11 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 333.0
HKD2_k127_3906225_12 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 320.0
HKD2_k127_3906225_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 301.0
HKD2_k127_3906225_14 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001349 301.0
HKD2_k127_3906225_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001273 286.0
HKD2_k127_3906225_16 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003476 272.0
HKD2_k127_3906225_17 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001842 273.0
HKD2_k127_3906225_18 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000009099 241.0
HKD2_k127_3906225_19 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000003536 241.0
HKD2_k127_3906225_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 511.0
HKD2_k127_3906225_20 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000009259 190.0
HKD2_k127_3906225_21 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000001122 181.0
HKD2_k127_3906225_22 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000003175 184.0
HKD2_k127_3906225_23 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000008654 154.0
HKD2_k127_3906225_24 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000003018 136.0
HKD2_k127_3906225_25 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000001939 131.0
HKD2_k127_3906225_26 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000002013 130.0
HKD2_k127_3906225_27 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000597 118.0
HKD2_k127_3906225_28 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000001193 111.0
HKD2_k127_3906225_29 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000003233 108.0
HKD2_k127_3906225_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 512.0
HKD2_k127_3906225_30 phosphocarrier protein HPr K11189 - - 0.00000000000000000000654 107.0
HKD2_k127_3906225_31 Lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.000000000000000001127 94.0
HKD2_k127_3906225_32 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.000000000000000001872 99.0
HKD2_k127_3906225_33 Yip1 domain - - - 0.000000000005593 74.0
HKD2_k127_3906225_34 Modulates RecA activity K03565 - - 0.00000003045 62.0
HKD2_k127_3906225_35 Lipopolysaccharide-assembly, LptC-related - - - 0.00004881 53.0
HKD2_k127_3906225_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 503.0
HKD2_k127_3906225_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 464.0
HKD2_k127_3906225_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 454.0
HKD2_k127_3906225_7 arylsulfatase A K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 355.0
HKD2_k127_3906225_8 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 364.0
HKD2_k127_3906225_9 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 338.0
HKD2_k127_3938220_0 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 378.0
HKD2_k127_3938220_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001543 259.0
HKD2_k127_3939080_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 545.0
HKD2_k127_3939080_1 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 461.0
HKD2_k127_3939080_2 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004364 291.0
HKD2_k127_3939080_3 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000007805 188.0
HKD2_k127_3939080_4 rod shape-determining protein MreD K03571 - - 0.0000003469 58.0
HKD2_k127_3958068_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.344e-232 732.0
HKD2_k127_3958068_1 transmembrane transporter activity K03296,K07788,K07789 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 464.0
HKD2_k127_3958068_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18313 - 2.8.3.16,2.8.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 362.0
HKD2_k127_3958068_3 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 311.0
HKD2_k127_3958068_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000009072 224.0
HKD2_k127_3958068_5 Predicted membrane protein (DUF2238) - - - 0.00000000000000000000000000000000000000000000000002748 186.0
HKD2_k127_3958068_6 - - - - 0.000000000000000000000000000001247 141.0
HKD2_k127_3958068_7 FAD dependent oxidoreductase K09471 - - 0.0000000000000000005211 99.0
HKD2_k127_3958068_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000001605 72.0
HKD2_k127_3969885_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1558.0
HKD2_k127_3969885_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1184.0
HKD2_k127_3969885_10 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 517.0
HKD2_k127_3969885_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 492.0
HKD2_k127_3969885_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 486.0
HKD2_k127_3969885_13 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 479.0
HKD2_k127_3969885_14 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 471.0
HKD2_k127_3969885_15 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 431.0
HKD2_k127_3969885_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 411.0
HKD2_k127_3969885_17 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 394.0
HKD2_k127_3969885_18 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 386.0
HKD2_k127_3969885_19 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 391.0
HKD2_k127_3969885_2 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 4.344e-275 908.0
HKD2_k127_3969885_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 384.0
HKD2_k127_3969885_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 395.0
HKD2_k127_3969885_22 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 391.0
HKD2_k127_3969885_23 quinone binding K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 349.0
HKD2_k127_3969885_24 associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 331.0
HKD2_k127_3969885_25 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 341.0
HKD2_k127_3969885_26 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 321.0
HKD2_k127_3969885_27 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 339.0
HKD2_k127_3969885_28 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 313.0
HKD2_k127_3969885_29 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 312.0
HKD2_k127_3969885_3 Protein of unknown function (DUF1343) - - - 2.93e-201 637.0
HKD2_k127_3969885_30 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 289.0
HKD2_k127_3969885_31 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005778 258.0
HKD2_k127_3969885_32 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000003177 250.0
HKD2_k127_3969885_33 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009391 257.0
HKD2_k127_3969885_34 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002109 239.0
HKD2_k127_3969885_35 Wax ester synthase-like Acyl-CoA acyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007072 248.0
HKD2_k127_3969885_36 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000008244 240.0
HKD2_k127_3969885_37 TRAM domain K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000724 240.0
HKD2_k127_3969885_38 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000001163 244.0
HKD2_k127_3969885_39 Belongs to the PAPS reductase family. CysH subfamily K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000001321 221.0
HKD2_k127_3969885_4 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 595.0
HKD2_k127_3969885_40 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000003813 207.0
HKD2_k127_3969885_41 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000002791 207.0
HKD2_k127_3969885_42 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000005057 199.0
HKD2_k127_3969885_43 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000003765 200.0
HKD2_k127_3969885_44 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000009324 198.0
HKD2_k127_3969885_45 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000001567 179.0
HKD2_k127_3969885_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000002098 176.0
HKD2_k127_3969885_47 Protein containing von Willebrand factor type A (VWA) domain K07161 - - 0.00000000000000000000000000000000000000000006177 175.0
HKD2_k127_3969885_48 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.0000000000000000000000000000000000000000001183 170.0
HKD2_k127_3969885_49 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000168 164.0
HKD2_k127_3969885_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 571.0
HKD2_k127_3969885_50 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000002276 162.0
HKD2_k127_3969885_51 Beta-lactamase - - - 0.0000000000000000000000000000000000000000004327 163.0
HKD2_k127_3969885_52 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000004409 154.0
HKD2_k127_3969885_53 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000001831 156.0
HKD2_k127_3969885_54 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000428 151.0
HKD2_k127_3969885_55 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000002181 160.0
HKD2_k127_3969885_56 NUDIX domain - - - 0.000000000000000000000000000000000003774 145.0
HKD2_k127_3969885_57 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000005287 139.0
HKD2_k127_3969885_58 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000006954 137.0
HKD2_k127_3969885_59 chlorophyll binding - - - 0.0000000000000000000000000000000004693 145.0
HKD2_k127_3969885_6 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 568.0
HKD2_k127_3969885_60 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000001633 148.0
HKD2_k127_3969885_61 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000174 146.0
HKD2_k127_3969885_62 - - - - 0.0000000000000000000000000000003758 140.0
HKD2_k127_3969885_63 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000002733 130.0
HKD2_k127_3969885_64 TPM domain K06872 - - 0.000000000000000000000000000006604 129.0
HKD2_k127_3969885_65 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000001241 128.0
HKD2_k127_3969885_66 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000306 124.0
HKD2_k127_3969885_67 nucleotidyltransferase activity - - - 0.0000000000000000000000000362 123.0
HKD2_k127_3969885_68 rieske 2fe-2s - - - 0.00000000000000000000000008691 114.0
HKD2_k127_3969885_69 PFAM CBS domain containing protein K07168 - - 0.000000000000000000000004801 118.0
HKD2_k127_3969885_7 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 556.0
HKD2_k127_3969885_70 phosphotransferase related to Ser Thr protein K07102 - 2.7.1.221 0.000000000000000000002012 107.0
HKD2_k127_3969885_71 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000002286 109.0
HKD2_k127_3969885_72 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000003857 105.0
HKD2_k127_3969885_73 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000008094 93.0
HKD2_k127_3969885_74 Trypsin-like serine protease K01312 - 3.4.21.4 0.0000000000000007591 91.0
HKD2_k127_3969885_75 Bifunctional sulfur carrier protein thiazole synthase K03154 - - 0.000000000000007738 85.0
HKD2_k127_3969885_76 Domain of unknown function (DUF309) K09763 - - 0.000000000007307 78.0
HKD2_k127_3969885_77 Protein of unknown function (DUF721) - - - 0.00000000001345 69.0
HKD2_k127_3969885_79 Alpha beta hydrolase - - - 0.0000003765 61.0
HKD2_k127_3969885_8 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 574.0
HKD2_k127_3969885_80 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.00002207 51.0
HKD2_k127_3969885_81 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0001669 51.0
HKD2_k127_3969885_9 PFAM deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 527.0
HKD2_k127_4044549_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.168e-286 889.0
HKD2_k127_4044549_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 505.0
HKD2_k127_4044549_10 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 336.0
HKD2_k127_4044549_11 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 329.0
HKD2_k127_4044549_12 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 314.0
HKD2_k127_4044549_13 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000107 288.0
HKD2_k127_4044549_14 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000395 256.0
HKD2_k127_4044549_15 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000003926 245.0
HKD2_k127_4044549_16 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000001632 239.0
HKD2_k127_4044549_17 copper ion homeostasis K07152,K12818 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000006622 212.0
HKD2_k127_4044549_18 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001147 202.0
HKD2_k127_4044549_19 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000004556 206.0
HKD2_k127_4044549_2 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 491.0
HKD2_k127_4044549_20 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000001921 216.0
HKD2_k127_4044549_21 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000006109 194.0
HKD2_k127_4044549_22 - - - - 0.0000000000000000000000000000000000000000000002374 175.0
HKD2_k127_4044549_23 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000001327 178.0
HKD2_k127_4044549_24 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000005008 186.0
HKD2_k127_4044549_25 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000001434 158.0
HKD2_k127_4044549_26 Glutathione S-Transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000002524 149.0
HKD2_k127_4044549_27 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000007718 132.0
HKD2_k127_4044549_28 - - - - 0.00000000000000000000000000009923 124.0
HKD2_k127_4044549_29 metallopeptidase activity - - - 0.000000000000000000000001056 120.0
HKD2_k127_4044549_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 443.0
HKD2_k127_4044549_30 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000002097 102.0
HKD2_k127_4044549_31 Ferric reductase like transmembrane component - - - 0.0000000000000000000004222 109.0
HKD2_k127_4044549_32 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000002994 91.0
HKD2_k127_4044549_33 ubiE/COQ5 methyltransferase family K22438 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464,GO:0046547 2.1.1.145 0.000000000004853 81.0
HKD2_k127_4044549_34 Thioesterase superfamily K07107 - - 0.00000001102 68.0
HKD2_k127_4044549_35 ATP-independent chaperone mediated protein folding K06006 - - 0.000001038 58.0
HKD2_k127_4044549_4 Binding-protein-dependent transport system inner membrane component K02050,K15552,K15554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 399.0
HKD2_k127_4044549_5 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 388.0
HKD2_k127_4044549_6 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 399.0
HKD2_k127_4044549_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 382.0
HKD2_k127_4044549_8 Abc transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 347.0
HKD2_k127_4044549_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 349.0
HKD2_k127_4052454_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 320.0
HKD2_k127_4052454_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002009 265.0
HKD2_k127_4052454_2 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000008703 135.0
HKD2_k127_4062299_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.127e-196 627.0
HKD2_k127_4062299_1 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 317.0
HKD2_k127_4062299_10 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000005647 230.0
HKD2_k127_4062299_11 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000006903 215.0
HKD2_k127_4062299_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000006887 148.0
HKD2_k127_4062299_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000008961 113.0
HKD2_k127_4062299_14 Phosphopantetheine attachment site K02078 - - 0.0000000000003813 75.0
HKD2_k127_4062299_16 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000001859 74.0
HKD2_k127_4062299_17 Transcriptional regulator PadR-like family - - - 0.0002803 51.0
HKD2_k127_4062299_2 Sigma-54 interaction domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 304.0
HKD2_k127_4062299_3 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009552 302.0
HKD2_k127_4062299_4 Belongs to the beta-ketoacyl-ACP synthases family K05551,K09458 - 2.3.1.179,2.3.1.235,2.3.1.260 0.000000000000000000000000000000000000000000000000000000000000000000000000000005144 274.0
HKD2_k127_4062299_5 Beta-ketoacyl synthase, C-terminal domain K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000003342 274.0
HKD2_k127_4062299_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004237 252.0
HKD2_k127_4062299_7 FAD metabolic process K00953,K15429 GO:0003674,GO:0003824,GO:0003919,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042726,GO:0042727,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046443,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070566,GO:0071704,GO:0071944,GO:0072387,GO:0072388,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.228,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000003992 225.0
HKD2_k127_4062299_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000002722 233.0
HKD2_k127_4062299_9 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000002313 222.0
HKD2_k127_4066378_0 Pyridine nucleotide-disulphide oxidoreductase - - - 5.892e-215 681.0
HKD2_k127_4066378_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 482.0
HKD2_k127_4066378_10 monooxygenase activity - - - 0.0000000000000000000000000001717 118.0
HKD2_k127_4066378_11 transferase activity, transferring glycosyl groups K20444 - - 0.000000000000000000000003003 111.0
HKD2_k127_4066378_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 487.0
HKD2_k127_4066378_3 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 401.0
HKD2_k127_4066378_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 332.0
HKD2_k127_4066378_5 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 331.0
HKD2_k127_4066378_6 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002143 276.0
HKD2_k127_4066378_7 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000005957 198.0
HKD2_k127_4066378_8 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.0000000000000000000000000000000000001099 145.0
HKD2_k127_4066378_9 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000008357 157.0
HKD2_k127_4067128_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 1.057e-222 704.0
HKD2_k127_4067128_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 476.0
HKD2_k127_4067128_10 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000001012 186.0
HKD2_k127_4067128_11 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000002772 165.0
HKD2_k127_4067128_12 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.0000000000000000000000000000000006452 151.0
HKD2_k127_4067128_13 PAS domain - - - 0.0000000000000000000000000000000035 144.0
HKD2_k127_4067128_14 extracellular matrix structural constituent - - - 0.0000000000000000005099 101.0
HKD2_k127_4067128_15 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000005737 81.0
HKD2_k127_4067128_2 hydrolase or acyltransferase of alpha beta superfamily K01253 - 3.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 442.0
HKD2_k127_4067128_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 388.0
HKD2_k127_4067128_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 405.0
HKD2_k127_4067128_5 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 327.0
HKD2_k127_4067128_6 (2R)-phospho-3-sulfolactate synthase (ComA) K08097 - 4.4.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001275 285.0
HKD2_k127_4067128_7 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000009845 243.0
HKD2_k127_4067128_8 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000000002469 186.0
HKD2_k127_4067128_9 Peptidyl-prolyl cis-trans K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000008 186.0
HKD2_k127_4086317_0 amine dehydrogenase activity - - - 4.7e-322 1021.0
HKD2_k127_4086317_1 Sulfatase K01130 - 3.1.6.1 1.528e-250 804.0
HKD2_k127_4086317_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003615 289.0
HKD2_k127_4086317_11 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001347 271.0
HKD2_k127_4086317_12 ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003263 255.0
HKD2_k127_4086317_13 Protein of unknown function (DUF1272) K09984 - - 0.00000000000000000000000000000000000000000000001074 181.0
HKD2_k127_4086317_14 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000003619 182.0
HKD2_k127_4086317_15 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000188 175.0
HKD2_k127_4086317_16 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000002051 162.0
HKD2_k127_4086317_17 Histidine kinase K07646,K07679 - 2.7.13.3 0.0000000000000000000000000000000000000003316 171.0
HKD2_k127_4086317_18 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000002532 154.0
HKD2_k127_4086317_19 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000002154 148.0
HKD2_k127_4086317_2 PFAM class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 622.0
HKD2_k127_4086317_21 - - - - 0.0000000000000000000000009131 113.0
HKD2_k127_4086317_22 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000001368 95.0
HKD2_k127_4086317_23 SnoaL-like domain - - - 0.0000000000002185 76.0
HKD2_k127_4086317_25 TonB-dependent receptor - - - 0.0004455 46.0
HKD2_k127_4086317_3 Putative citrate transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 533.0
HKD2_k127_4086317_4 antibiotic catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 455.0
HKD2_k127_4086317_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 418.0
HKD2_k127_4086317_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 399.0
HKD2_k127_4086317_7 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 393.0
HKD2_k127_4086317_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 309.0
HKD2_k127_4086317_9 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 321.0
HKD2_k127_4140419_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 7.378e-272 849.0
HKD2_k127_4140419_1 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 511.0
HKD2_k127_4140419_3 ABC-type polar amino acid transport system ATPase component K02028,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000006526 260.0
HKD2_k127_4140419_4 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000002239 198.0
HKD2_k127_4140419_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000001563 171.0
HKD2_k127_4140419_6 alpha beta - - - 0.00000000016 64.0
HKD2_k127_4156872_0 UvrD/REP helicase N-terminal domain - - - 0.0 1131.0
HKD2_k127_4156872_1 PD-(D/E)XK nuclease superfamily - - - 2.414e-289 927.0
HKD2_k127_4156872_10 Zinc-uptake complex component A periplasmic K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001276 281.0
HKD2_k127_4156872_11 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000304 271.0
HKD2_k127_4156872_12 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005476 291.0
HKD2_k127_4156872_13 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002522 266.0
HKD2_k127_4156872_14 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002317 240.0
HKD2_k127_4156872_15 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000003285 233.0
HKD2_k127_4156872_16 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001178 223.0
HKD2_k127_4156872_17 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000004863 219.0
HKD2_k127_4156872_18 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0017144,GO:0018130,GO:0019752,GO:0032259,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.000000000000000000000000000000000000000000000103 178.0
HKD2_k127_4156872_19 PFAM ABC transporter K09817 - - 0.00000000000000000000000000000000000000000002641 181.0
HKD2_k127_4156872_2 C-terminus of AA_permease K03294 - - 9.194e-200 633.0
HKD2_k127_4156872_20 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000001344 181.0
HKD2_k127_4156872_21 domain, Protein - - - 0.000000000000000000000000000000000000003614 168.0
HKD2_k127_4156872_22 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000004364 133.0
HKD2_k127_4156872_23 YGGT family K02221 - - 0.000000000000000000000000000007011 123.0
HKD2_k127_4156872_24 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000007766 103.0
HKD2_k127_4156872_25 Cytochrome c K17222 - - 0.000000000000000000002449 107.0
HKD2_k127_4156872_26 Putative regulatory protein - - - 0.00000000000000003513 88.0
HKD2_k127_4156872_27 COG3119 Arylsulfatase A K01138 - - 0.00000000000001194 89.0
HKD2_k127_4156872_28 Belongs to the UPF0235 family K09131 - - 0.0000000001372 68.0
HKD2_k127_4156872_29 PFAM MgtE intracellular - - - 0.000000002481 65.0
HKD2_k127_4156872_3 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 595.0
HKD2_k127_4156872_30 Protein of unknown function (DUF507) - - - 0.000005587 58.0
HKD2_k127_4156872_31 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000009256 59.0
HKD2_k127_4156872_4 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 576.0
HKD2_k127_4156872_5 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 452.0
HKD2_k127_4156872_6 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 435.0
HKD2_k127_4156872_7 Phosphoinositide phospholipase C, Ca2+-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 384.0
HKD2_k127_4156872_8 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179,K03832 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 334.0
HKD2_k127_4156872_9 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000693 285.0
HKD2_k127_4181023_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
HKD2_k127_4181023_1 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.000000000000000000000000008577 120.0
HKD2_k127_4193752_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000007485 258.0
HKD2_k127_4193752_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000005123 141.0
HKD2_k127_4222958_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 587.0
HKD2_k127_4222958_1 Aldehyde dehydrogenase family K00129 - 1.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 578.0
HKD2_k127_4222958_2 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 514.0
HKD2_k127_4222958_3 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 458.0
HKD2_k127_4222958_4 Glycosyl hydrolases family 31 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 306.0
HKD2_k127_4222958_5 palmitoyl-(protein) hydrolase activity K06999 - - 0.000000000000000000000000000000000000000003918 180.0
HKD2_k127_4222958_7 - K01822 - 5.3.3.1 0.000004971 55.0
HKD2_k127_4239655_0 Lon protease (S16) C-terminal proteolytic domain K01338 - 3.4.21.53 0.0 1113.0
HKD2_k127_4239655_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 2.094e-232 771.0
HKD2_k127_4239655_10 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 301.0
HKD2_k127_4239655_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003656 295.0
HKD2_k127_4239655_12 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001276 283.0
HKD2_k127_4239655_13 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000425 292.0
HKD2_k127_4239655_14 S-adenosyl-L-homocysteine hydrolase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 275.0
HKD2_k127_4239655_15 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002647 275.0
HKD2_k127_4239655_16 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009975,GO:0016874,GO:0016886,GO:0044424,GO:0044464,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007226 267.0
HKD2_k127_4239655_17 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002358 237.0
HKD2_k127_4239655_18 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001704 248.0
HKD2_k127_4239655_19 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002288 231.0
HKD2_k127_4239655_2 NAD(P)-binding Rossmann-like domain - - - 1.765e-231 748.0
HKD2_k127_4239655_20 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000377 199.0
HKD2_k127_4239655_21 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000009544 155.0
HKD2_k127_4239655_22 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000002696 142.0
HKD2_k127_4239655_23 - - - - 0.000000000000000000000000000005455 130.0
HKD2_k127_4239655_24 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000001602 122.0
HKD2_k127_4239655_25 Putative DNA-binding domain - - - 0.00000000000000000000000005045 120.0
HKD2_k127_4239655_26 Bacterial regulatory proteins, tetR family - - - 0.000000000000000003894 93.0
HKD2_k127_4239655_27 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.00000000000246 79.0
HKD2_k127_4239655_28 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000001194 69.0
HKD2_k127_4239655_29 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000001572 69.0
HKD2_k127_4239655_3 COG0464 ATPases of the AAA class - - - 3.769e-214 676.0
HKD2_k127_4239655_30 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000359 68.0
HKD2_k127_4239655_31 Sh3 type 3 domain protein - - - 0.00000007673 66.0
HKD2_k127_4239655_32 - - - - 0.000002855 59.0
HKD2_k127_4239655_33 domain, Protein K20276 - - 0.000002938 61.0
HKD2_k127_4239655_35 PFAM Cytochrome C - - - 0.0001052 56.0
HKD2_k127_4239655_36 Cytochrome c K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0001385 56.0
HKD2_k127_4239655_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 593.0
HKD2_k127_4239655_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 471.0
HKD2_k127_4239655_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 440.0
HKD2_k127_4239655_7 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 394.0
HKD2_k127_4239655_8 protein conserved in bacteria K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 362.0
HKD2_k127_4239655_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 341.0
HKD2_k127_4264058_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 453.0
HKD2_k127_4264058_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000244 278.0
HKD2_k127_4264058_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
HKD2_k127_4264058_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000108 228.0
HKD2_k127_4264058_4 Nudix hydrolase - - - 0.000000000000000000000000000000000001951 149.0
HKD2_k127_4264058_5 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000001565 137.0
HKD2_k127_4264058_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000002272 138.0
HKD2_k127_4284311_0 transcription factor binding K15836 - - 1.563e-277 876.0
HKD2_k127_4284311_1 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 3.056e-246 782.0
HKD2_k127_4284311_10 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 302.0
HKD2_k127_4284311_11 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004401 284.0
HKD2_k127_4284311_12 GMC oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000006528 272.0
HKD2_k127_4284311_13 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000001666 254.0
HKD2_k127_4284311_14 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000003259 185.0
HKD2_k127_4284311_15 TraB family K09973 - - 0.000000000000000000000000000000000000000000000009065 185.0
HKD2_k127_4284311_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000005796 168.0
HKD2_k127_4284311_17 lactoylglutathione lyase activity K11210,K21253,K21264,K21265 GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 2.5.1.18 0.00000000000000000000000000000000000003774 152.0
HKD2_k127_4284311_18 SnoaL-like domain - - - 0.000000000000000000000000000000009319 131.0
HKD2_k127_4284311_19 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000267 126.0
HKD2_k127_4284311_2 PFAM Glycoside hydrolase 15-related - - - 1.911e-214 709.0
HKD2_k127_4284311_20 Cytochrome c554 and c-prime - - - 0.0000000000000000000000001907 124.0
HKD2_k127_4284311_21 PKD domain - - - 0.00000000000000000001529 109.0
HKD2_k127_4284311_22 Tetratricopeptide repeat - - - 0.00000000000000005707 96.0
HKD2_k127_4284311_23 SMART LamG domain protein jellyroll fold domain protein - - - 0.000000001916 66.0
HKD2_k127_4284311_24 Oxidoreductase - - - 0.00007082 53.0
HKD2_k127_4284311_26 - - - - 0.0005153 53.0
HKD2_k127_4284311_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 543.0
HKD2_k127_4284311_4 COG1012 NAD-dependent aldehyde dehydrogenases K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 458.0
HKD2_k127_4284311_5 SbmA/BacA-like family K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 471.0
HKD2_k127_4284311_6 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 426.0
HKD2_k127_4284311_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 411.0
HKD2_k127_4284311_8 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 365.0
HKD2_k127_4284311_9 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 347.0
HKD2_k127_4309552_0 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1158.0
HKD2_k127_4309552_1 response to heat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
HKD2_k127_4309552_2 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.0000000000001123 74.0
HKD2_k127_4339798_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 3.697e-287 904.0
HKD2_k127_4339798_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 320.0
HKD2_k127_4339798_2 Responsible for synthesis of pseudouridine from uracil - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 301.0
HKD2_k127_4339798_3 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001039 272.0
HKD2_k127_4339798_4 regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000004529 192.0
HKD2_k127_4339798_5 MAPEG family - - - 0.0000000000000000000000000000001254 141.0
HKD2_k127_4339798_6 Thrombospondin type 3 - - - 0.00000000000008113 83.0
HKD2_k127_4339798_7 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 GO:0005575,GO:0005576 1.3.3.11 0.000002069 59.0
HKD2_k127_4339798_8 Protein of unknown function (DUF2889) - - - 0.00005234 55.0
HKD2_k127_4339798_9 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0003404 53.0
HKD2_k127_4370883_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 8.311e-295 923.0
HKD2_k127_4370883_1 Circularly permuted ATP-grasp type 2 - - - 2.217e-238 745.0
HKD2_k127_4370883_10 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000001905 169.0
HKD2_k127_4370883_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000006158 156.0
HKD2_k127_4370883_12 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000001401 170.0
HKD2_k127_4370883_13 PFAM EAL domain - - - 0.00000000000000000000000000000000002796 138.0
HKD2_k127_4370883_14 zinc metalloprotease - - - 0.000000000000000000000000000004063 139.0
HKD2_k127_4370883_15 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000152 82.0
HKD2_k127_4370883_16 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000003197 73.0
HKD2_k127_4370883_17 PFAM short chain dehydrogenase - - - 0.000003684 59.0
HKD2_k127_4370883_18 O-Antigen ligase K18814 - - 0.00002964 57.0
HKD2_k127_4370883_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 488.0
HKD2_k127_4370883_3 succinylglutamate desuccinylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 414.0
HKD2_k127_4370883_4 Desuccinylase aspartoacylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 346.0
HKD2_k127_4370883_5 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 313.0
HKD2_k127_4370883_6 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 319.0
HKD2_k127_4370883_7 Bacterial transglutaminase-like N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001297 279.0
HKD2_k127_4370883_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000001411 198.0
HKD2_k127_4370883_9 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000004493 175.0
HKD2_k127_44867_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18299 - - 0.0 1049.0
HKD2_k127_44867_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 436.0
HKD2_k127_44867_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19586 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 329.0
HKD2_k127_4503020_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.482e-270 841.0
HKD2_k127_4503020_1 Amylo-alpha-1,6-glucosidase - - - 2.151e-260 817.0
HKD2_k127_4503020_2 choline dehydrogenase activity - - - 6.685e-222 700.0
HKD2_k127_4503020_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 426.0
HKD2_k127_4503020_4 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 380.0
HKD2_k127_4503020_5 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 287.0
HKD2_k127_4503020_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
HKD2_k127_451526_0 Bacterial regulatory proteins, gntR family K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 498.0
HKD2_k127_451526_1 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 404.0
HKD2_k127_451526_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
HKD2_k127_451526_3 Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000000000000000372 180.0
HKD2_k127_451526_4 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000003146 85.0
HKD2_k127_451526_5 Alkyl sulfatase C-terminal - - - 0.0000000001107 73.0
HKD2_k127_4604952_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006541 281.0
HKD2_k127_4604952_1 carboxylase K01968 - 6.4.1.4 0.0000000000000009066 80.0
HKD2_k127_473473_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001002 250.0
HKD2_k127_473473_1 xylulokinase activity K00879,K11216 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006004,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008737,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046372,GO:0046835,GO:0071704,GO:1901575 2.7.1.189,2.7.1.51 0.0000000000000000000000000000000000000000000000000000000000000000008268 257.0
HKD2_k127_473473_10 Cytochrome c - - - 0.00005556 55.0
HKD2_k127_473473_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.00000000000000000000000000000000000000000000000000000000000000002923 250.0
HKD2_k127_473473_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000001852 228.0
HKD2_k127_473473_4 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000001931 200.0
HKD2_k127_473473_6 ACT domain - - - 0.00000000000000000000000000000000376 137.0
HKD2_k127_473473_7 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000175 123.0
HKD2_k127_473473_8 PFAM Cold-shock protein DNA-binding K03704 - - 0.000000000000000000000003594 108.0
HKD2_k127_473473_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000127 73.0
HKD2_k127_4878184_0 carbohydrate binding K00702 - 2.4.1.20 6.924e-219 705.0
HKD2_k127_4878184_1 Alpha-amylase domain K01182,K01187 - 3.2.1.10,3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 515.0
HKD2_k127_4878184_10 Stigma-specific protein, Stig1 - GO:0000003,GO:0003006,GO:0005575,GO:0005576,GO:0007275,GO:0008150,GO:0009790,GO:0009791,GO:0009793,GO:0010154,GO:0022414,GO:0032501,GO:0032502,GO:0042335,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061458 - 0.0005248 53.0
HKD2_k127_4878184_2 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 484.0
HKD2_k127_4878184_3 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000000000000000000000000000000000000000000000000000000000002418 265.0
HKD2_k127_4878184_4 Glycosyl transferase family 8 - - - 0.000000000000000000000000000000000000149 152.0
HKD2_k127_4878184_5 Cupin domain - - - 0.0000000000000000000000000000000000001641 145.0
HKD2_k127_4878184_6 Stigma-specific protein, Stig1 - - - 0.000000000000000000000008241 119.0
HKD2_k127_4878184_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000001152 78.0
HKD2_k127_4878184_8 transferase K02851 - 2.7.8.33,2.7.8.35 0.000002662 57.0
HKD2_k127_4878184_9 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00004872 55.0
HKD2_k127_4974399_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 413.0
HKD2_k127_4974399_1 PFAM Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 379.0
HKD2_k127_4974399_2 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000001685 200.0
HKD2_k127_4974399_3 PAS fold - - - 0.0000000000000000007569 94.0
HKD2_k127_502608_0 Fumarase C-terminus K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 5.04e-253 798.0
HKD2_k127_502608_1 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 509.0
HKD2_k127_502608_2 Domain of unknown function (DUF1330) - - - 0.000000000000000009107 90.0
HKD2_k127_507888_0 COG2211 Na melibiose symporter and related transporters K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 448.0
HKD2_k127_507888_1 PFAM Peptidase M11 gametolysin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 398.0
HKD2_k127_507888_2 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000005781 208.0
HKD2_k127_507888_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000003158 153.0
HKD2_k127_507888_4 thioesterase - - - 0.0000000000000000000000000000000003262 139.0
HKD2_k127_507888_5 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000002 130.0
HKD2_k127_507888_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00003331 46.0
HKD2_k127_5093287_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.308e-234 746.0
HKD2_k127_5093287_1 KR domain - - - 2.448e-205 673.0
HKD2_k127_5093287_10 Glycosyltransferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 393.0
HKD2_k127_5093287_11 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 396.0
HKD2_k127_5093287_12 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 407.0
HKD2_k127_5093287_13 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 365.0
HKD2_k127_5093287_14 PFAM secretion protein HlyD family protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 332.0
HKD2_k127_5093287_15 Peroxidase K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003961 267.0
HKD2_k127_5093287_16 Diacylglycerol O-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001608 254.0
HKD2_k127_5093287_17 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000001648 188.0
HKD2_k127_5093287_18 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000001046 167.0
HKD2_k127_5093287_19 Protein of unknown function (DUF1329) - - - 0.0000000000000000000000000000000000000000001457 177.0
HKD2_k127_5093287_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 587.0
HKD2_k127_5093287_20 ATPase activity, coupled to transmembrane movement of substances K02120 - - 0.00000000000000000000000000000000002003 143.0
HKD2_k127_5093287_21 Histidine kinase K02668,K07710 - 2.7.13.3 0.0000000000000000000000000001045 134.0
HKD2_k127_5093287_22 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 GO:0000287,GO:0003674,GO:0003824,GO:0004805,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0034637,GO:0040007,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0071704,GO:0071944,GO:1901576 3.1.3.12 0.0000000000000000000000001242 118.0
HKD2_k127_5093287_23 Bacterial regulatory protein, Fis family K07715 - - 0.000000000000000000000001111 121.0
HKD2_k127_5093287_24 Sh3 type 3 domain protein - - - 0.00000000000000000000003848 116.0
HKD2_k127_5093287_25 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000000000000003857 94.0
HKD2_k127_5093287_26 subunit (C K02119 - - 0.000000000000000000392 101.0
HKD2_k127_5093287_27 AMP binding - - - 0.00000000000000002405 90.0
HKD2_k127_5093287_28 domain protein - - - 0.000000000000005771 90.0
HKD2_k127_5093287_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 608.0
HKD2_k127_5093287_30 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000003569 68.0
HKD2_k127_5093287_31 Transcription factor zinc-finger K09981 - - 0.00004144 52.0
HKD2_k127_5093287_4 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 501.0
HKD2_k127_5093287_5 transferase activity, transferring glycosyl groups K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 484.0
HKD2_k127_5093287_6 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 465.0
HKD2_k127_5093287_7 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 454.0
HKD2_k127_5093287_8 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 407.0
HKD2_k127_5093287_9 (ABC) transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 390.0
HKD2_k127_5127394_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 480.0
HKD2_k127_5127394_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 398.0
HKD2_k127_5127394_10 N-terminal half of MaoC dehydratase - - - 0.00000000000000003032 88.0
HKD2_k127_5127394_11 Bacterial regulatory proteins, tetR family - - - 0.0000000000000001496 91.0
HKD2_k127_5127394_12 Protein of unknown function (DUF971) K03593 - - 0.000000001372 65.0
HKD2_k127_5127394_2 acetyl-coa acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000609 266.0
HKD2_k127_5127394_3 Dehydrogenase K00059 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.100 0.00000000000000000000000000000000000000000000000000000003473 207.0
HKD2_k127_5127394_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000669 178.0
HKD2_k127_5127394_5 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000007451 175.0
HKD2_k127_5127394_6 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000001967 159.0
HKD2_k127_5127394_7 Serine aminopeptidase, S33 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000001361 143.0
HKD2_k127_5127394_8 Amidohydrolase - - - 0.0000000000000000000000000000002339 137.0
HKD2_k127_5127394_9 MaoC like domain - - - 0.00000000000000000000000000003976 128.0
HKD2_k127_5144456_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 580.0
HKD2_k127_5144456_1 twitching motility protein K02669 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 421.0
HKD2_k127_5144456_2 TIGRFAM cysteine-rich repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001647 286.0
HKD2_k127_5144456_3 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007959 266.0
HKD2_k127_5144456_4 peptidylprolyl isomerase, FKBP-type K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
HKD2_k127_5144456_5 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000002329 191.0
HKD2_k127_5144456_6 protein heterodimerization activity - - - 0.000000000000000000000000000000000000005325 158.0
HKD2_k127_5144456_7 chondroitin AC lyase activity - - - 0.000000000000000000000000001865 127.0
HKD2_k127_5144456_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000001332 112.0
HKD2_k127_5153101_0 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 599.0
HKD2_k127_5153101_1 DNA photolyase domain protein K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 497.0
HKD2_k127_5153101_10 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.00000000000000000000000000000000000000001605 173.0
HKD2_k127_5153101_11 - - - - 0.0000000000000000000000000001121 119.0
HKD2_k127_5153101_12 peroxiredoxin activity K03386,K03564 - 1.11.1.15 0.0000000000000000000000000004211 129.0
HKD2_k127_5153101_13 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000001255 103.0
HKD2_k127_5153101_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000004952 98.0
HKD2_k127_5153101_15 - - - - 0.00000000000000000006786 95.0
HKD2_k127_5153101_16 CBS domain - - - 0.000000000000000004034 91.0
HKD2_k127_5153101_17 START domain - - - 0.00000000007959 74.0
HKD2_k127_5153101_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 477.0
HKD2_k127_5153101_3 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 378.0
HKD2_k127_5153101_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004606 284.0
HKD2_k127_5153101_5 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002355 255.0
HKD2_k127_5153101_6 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002801 255.0
HKD2_k127_5153101_7 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000003713 222.0
HKD2_k127_5153101_8 IMG reference gene - - - 0.000000000000000000000000000000000000000000000002699 195.0
HKD2_k127_5153101_9 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000003839 175.0
HKD2_k127_5195478_0 Belongs to the heat shock protein 70 family K04046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 392.0
HKD2_k127_5195478_1 Thiolase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 384.0
HKD2_k127_5195478_10 glycosyl transferase family 2 - - - 0.00000000000000000000000005686 125.0
HKD2_k127_5195478_11 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000341 94.0
HKD2_k127_5195478_12 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000001115 89.0
HKD2_k127_5195478_13 - - - - 0.000000000003485 72.0
HKD2_k127_5195478_15 -acetyltransferase - - - 0.000004447 55.0
HKD2_k127_5195478_2 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 394.0
HKD2_k127_5195478_3 GHMP kinases N terminal domain K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006836 290.0
HKD2_k127_5195478_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006256 278.0
HKD2_k127_5195478_5 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003849 276.0
HKD2_k127_5195478_6 ZIP Zinc transporter K07238,K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000000000001518 209.0
HKD2_k127_5195478_7 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000001208 191.0
HKD2_k127_5195478_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000003269 172.0
HKD2_k127_5195478_9 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000001971 160.0
HKD2_k127_5206356_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.734e-261 830.0
HKD2_k127_5206356_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 380.0
HKD2_k127_5206356_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000001188 136.0
HKD2_k127_5237960_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 2.968e-277 869.0
HKD2_k127_5237960_1 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 1.051e-255 830.0
HKD2_k127_5237960_10 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000007469 196.0
HKD2_k127_5237960_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000008596 172.0
HKD2_k127_5237960_12 thiolester hydrolase activity - - - 0.000000000000000000000000000000000288 137.0
HKD2_k127_5237960_13 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000000000000000000002615 135.0
HKD2_k127_5237960_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000007318 118.0
HKD2_k127_5237960_15 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000002009 119.0
HKD2_k127_5237960_16 U4 snRNA binding K11127 - - 0.000000000000000000000002385 118.0
HKD2_k127_5237960_17 response regulator, receiver - - - 0.000000000000000000001157 106.0
HKD2_k127_5237960_18 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000866 97.0
HKD2_k127_5237960_19 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000001029 98.0
HKD2_k127_5237960_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 495.0
HKD2_k127_5237960_20 aspartic-type endopeptidase activity - - - 0.000000000000000001323 96.0
HKD2_k127_5237960_21 Helix-turn-helix domain - - - 0.000000000008344 67.0
HKD2_k127_5237960_22 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000003104 67.0
HKD2_k127_5237960_23 Bacterial PH domain - - - 0.000005731 57.0
HKD2_k127_5237960_24 - - - - 0.0000191 54.0
HKD2_k127_5237960_25 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.0001213 55.0
HKD2_k127_5237960_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 411.0
HKD2_k127_5237960_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 380.0
HKD2_k127_5237960_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 263.0
HKD2_k127_5237960_6 CrtC N-terminal lipocalin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002457 253.0
HKD2_k127_5237960_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000006645 233.0
HKD2_k127_5237960_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000001659 194.0
HKD2_k127_5237960_9 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000003318 203.0
HKD2_k127_5264302_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.831e-278 888.0
HKD2_k127_5264302_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 591.0
HKD2_k127_5264302_10 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000002044 112.0
HKD2_k127_5264302_11 protein conserved in bacteria K09800 - - 0.00000000000000000001034 109.0
HKD2_k127_5264302_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 556.0
HKD2_k127_5264302_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 494.0
HKD2_k127_5264302_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 472.0
HKD2_k127_5264302_5 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 317.0
HKD2_k127_5264302_6 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002236 261.0
HKD2_k127_5264302_7 Surface antigen K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007455 260.0
HKD2_k127_5264302_8 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000001297 187.0
HKD2_k127_5264302_9 protein conserved in bacteria K09922 - - 0.0000000000000000000000000002659 126.0
HKD2_k127_5317849_0 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1996.0
HKD2_k127_5317849_1 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 2.768e-203 642.0
HKD2_k127_5317849_10 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000001924 142.0
HKD2_k127_5317849_11 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000002295 123.0
HKD2_k127_5317849_12 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000002828 84.0
HKD2_k127_5317849_13 metal cluster binding K06940,K18475 - - 0.00000000000007962 82.0
HKD2_k127_5317849_2 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 475.0
HKD2_k127_5317849_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 384.0
HKD2_k127_5317849_4 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 387.0
HKD2_k127_5317849_5 Catalyzes the synthesis of activated sulfate K00860 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002894 294.0
HKD2_k127_5317849_6 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009534 282.0
HKD2_k127_5317849_7 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000000001827 218.0
HKD2_k127_5317849_8 PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000006034 228.0
HKD2_k127_5317849_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000004829 180.0
HKD2_k127_5338784_0 GTP-binding protein TypA K06207 - - 7.602e-236 754.0
HKD2_k127_5338784_1 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 7.561e-222 723.0
HKD2_k127_5338784_10 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
HKD2_k127_5338784_11 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000001941 267.0
HKD2_k127_5338784_12 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009349 272.0
HKD2_k127_5338784_13 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001572 265.0
HKD2_k127_5338784_14 Iron Permease K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008304 271.0
HKD2_k127_5338784_15 May function as heme-dependent peroxidase K00435 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
HKD2_k127_5338784_16 Iron-regulated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006141 253.0
HKD2_k127_5338784_17 5'-3' exonuclease - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000006978 268.0
HKD2_k127_5338784_18 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000003578 239.0
HKD2_k127_5338784_19 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000002644 236.0
HKD2_k127_5338784_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.113e-215 685.0
HKD2_k127_5338784_20 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000327 233.0
HKD2_k127_5338784_21 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000005173 227.0
HKD2_k127_5338784_22 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003482 226.0
HKD2_k127_5338784_23 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000007103 211.0
HKD2_k127_5338784_24 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000002728 203.0
HKD2_k127_5338784_25 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000007493 205.0
HKD2_k127_5338784_26 DNA polymerase III, delta' K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000953 206.0
HKD2_k127_5338784_27 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000000000000000001002 199.0
HKD2_k127_5338784_28 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000000005938 194.0
HKD2_k127_5338784_29 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000004071 189.0
HKD2_k127_5338784_3 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 1.633e-194 640.0
HKD2_k127_5338784_30 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000001403 190.0
HKD2_k127_5338784_31 sterol desaturase - - - 0.0000000000000000000000000000000000000000000000002803 184.0
HKD2_k127_5338784_32 GAF domain - - - 0.000000000000000000000000000000000000000000002511 185.0
HKD2_k127_5338784_33 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000007377 160.0
HKD2_k127_5338784_34 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000003289 154.0
HKD2_k127_5338784_35 Haem utilisation ChuX/HutX K07225 - - 0.0000000000000000000000000000000001537 152.0
HKD2_k127_5338784_36 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000003738 140.0
HKD2_k127_5338784_37 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000000000000000001939 131.0
HKD2_k127_5338784_38 MAPEG family K07136 - - 0.00000000000000000000000000001045 123.0
HKD2_k127_5338784_39 PAS domain - - - 0.0000000000000000000000000004536 132.0
HKD2_k127_5338784_4 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 607.0
HKD2_k127_5338784_40 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000001554 115.0
HKD2_k127_5338784_41 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000007458 109.0
HKD2_k127_5338784_42 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000005702 99.0
HKD2_k127_5338784_43 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000009833 100.0
HKD2_k127_5338784_44 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000007085 97.0
HKD2_k127_5338784_46 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000008497 94.0
HKD2_k127_5338784_47 - - - - 0.000000001203 66.0
HKD2_k127_5338784_48 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000001572 58.0
HKD2_k127_5338784_49 - - - - 0.0000004534 57.0
HKD2_k127_5338784_5 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 545.0
HKD2_k127_5338784_50 Predicted membrane protein (DUF2339) - - - 0.0000005997 59.0
HKD2_k127_5338784_51 Thioesterase superfamily - - - 0.00005017 54.0
HKD2_k127_5338784_52 pilus assembly protein PilW - - - 0.00008138 53.0
HKD2_k127_5338784_6 Converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 478.0
HKD2_k127_5338784_7 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 466.0
HKD2_k127_5338784_8 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 454.0
HKD2_k127_5338784_9 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 387.0
HKD2_k127_5390027_0 Cytochrome P450 K05525,K20497 - 1.14.13.151,1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 452.0
HKD2_k127_5390027_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18313 - 2.8.3.16,2.8.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 377.0
HKD2_k127_5390027_10 YcdC-like protein, C-terminal region K09017 - - 0.000000000000002227 91.0
HKD2_k127_5390027_11 SnoaL-like domain - - - 0.0000000000001212 81.0
HKD2_k127_5390027_2 COG1062 Zn-dependent alcohol dehydrogenases, class III K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 337.0
HKD2_k127_5390027_3 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002656 290.0
HKD2_k127_5390027_4 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002145 269.0
HKD2_k127_5390027_5 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000532 239.0
HKD2_k127_5390027_6 SnoaL-like domain - - - 0.00000000000000000000000000005412 122.0
HKD2_k127_5390027_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000005786 105.0
HKD2_k127_5390027_8 transcriptional regulator K09017 - - 0.00000000000000000000008239 107.0
HKD2_k127_5390027_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - 0.00000000000000002734 92.0
HKD2_k127_5398636_0 short chain dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
HKD2_k127_5398636_1 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 325.0
HKD2_k127_5398636_2 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001084 293.0
HKD2_k127_5398636_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000253 243.0
HKD2_k127_5398636_4 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000009402 145.0
HKD2_k127_5398636_5 - - - - 0.000000000000000000000001326 106.0
HKD2_k127_5545599_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 563.0
HKD2_k127_5545599_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 568.0
HKD2_k127_5545599_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000002118 180.0
HKD2_k127_5545599_11 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000009486 152.0
HKD2_k127_5545599_12 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000001465 162.0
HKD2_k127_5545599_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000001437 126.0
HKD2_k127_5545599_14 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000006561 85.0
HKD2_k127_5545599_15 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002497 70.0
HKD2_k127_5545599_16 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000001501 80.0
HKD2_k127_5545599_17 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000006911 68.0
HKD2_k127_5545599_2 RNA polymerases D K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 430.0
HKD2_k127_5545599_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 311.0
HKD2_k127_5545599_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 299.0
HKD2_k127_5545599_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 308.0
HKD2_k127_5545599_6 PFAM glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002412 280.0
HKD2_k127_5545599_7 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000001028 262.0
HKD2_k127_5545599_8 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000002423 241.0
HKD2_k127_5545599_9 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000007593 192.0
HKD2_k127_5624186_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 525.0
HKD2_k127_5624186_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 387.0
HKD2_k127_5624186_2 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 352.0
HKD2_k127_5624186_3 COG0183 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 340.0
HKD2_k127_5624186_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 330.0
HKD2_k127_5624186_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 308.0
HKD2_k127_5624186_6 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000256 168.0
HKD2_k127_5624186_7 Peptidase family M23 K21472 - - 0.0000000000000000000000000000000000005823 151.0
HKD2_k127_5624186_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000006696 102.0
HKD2_k127_5624186_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.00003299 53.0
HKD2_k127_5662824_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.029e-217 693.0
HKD2_k127_5662824_1 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 596.0
HKD2_k127_5662824_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000001903 186.0
HKD2_k127_5662824_11 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000133 172.0
HKD2_k127_5662824_12 Lysin motif - - - 0.00000000000000000000000000000000000000000001008 173.0
HKD2_k127_5662824_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000007664 148.0
HKD2_k127_5662824_14 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000001134 135.0
HKD2_k127_5662824_15 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000005504 82.0
HKD2_k127_5662824_16 Belongs to the 'phage' integrase family - - - 0.0004217 42.0
HKD2_k127_5662824_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 396.0
HKD2_k127_5662824_3 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 341.0
HKD2_k127_5662824_4 PFAM 2-nitropropane dioxygenase NPD K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 306.0
HKD2_k127_5662824_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 301.0
HKD2_k127_5662824_6 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002817 254.0
HKD2_k127_5662824_7 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000001687 211.0
HKD2_k127_5662824_8 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000008198 204.0
HKD2_k127_5662824_9 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000006422 210.0
HKD2_k127_5663246_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 1.491e-271 861.0
HKD2_k127_5663246_1 amidohydrolase - - - 4.153e-217 690.0
HKD2_k127_5663246_10 Belongs to the HpcH HpaI aldolase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000776 229.0
HKD2_k127_5663246_11 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000007905 239.0
HKD2_k127_5663246_12 Pfam Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000008786 221.0
HKD2_k127_5663246_13 Pfam Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000002456 218.0
HKD2_k127_5663246_14 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000003813 207.0
HKD2_k127_5663246_15 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000006472 196.0
HKD2_k127_5663246_16 Domain of unknown function (DUF4281) - - - 0.0000000000000000000000000000000000000000000006206 169.0
HKD2_k127_5663246_17 Amidohydrolase - - - 0.0000000000000000000000000000000000000001243 167.0
HKD2_k127_5663246_18 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000004268 163.0
HKD2_k127_5663246_19 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000006691 114.0
HKD2_k127_5663246_2 synthetase K00666 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0032787,GO:0042546,GO:0042759,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0072330,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 478.0
HKD2_k127_5663246_20 SnoaL-like domain - - - 0.0000000000000000000001106 112.0
HKD2_k127_5663246_21 - - - - 0.00000000000000000001318 97.0
HKD2_k127_5663246_22 - - - - 0.00000000005376 72.0
HKD2_k127_5663246_23 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000002053 74.0
HKD2_k127_5663246_24 Armadillo/beta-catenin-like repeats - - - 0.0000004997 61.0
HKD2_k127_5663246_3 POT family K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 428.0
HKD2_k127_5663246_4 alcohol dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 396.0
HKD2_k127_5663246_5 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 381.0
HKD2_k127_5663246_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 348.0
HKD2_k127_5663246_7 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 328.0
HKD2_k127_5663246_8 Enoyl-coA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
HKD2_k127_5663246_9 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000004677 229.0
HKD2_k127_5672102_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.315e-317 981.0
HKD2_k127_5672102_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 502.0
HKD2_k127_5672102_10 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.000000000000000000000000000000000000000000000006734 189.0
HKD2_k127_5672102_11 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000002758 181.0
HKD2_k127_5672102_12 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000003112 169.0
HKD2_k127_5672102_13 GAF domain - - - 0.00000000000000000000000000000000000003153 163.0
HKD2_k127_5672102_14 dehydratase - - - 0.000000000000000000000000000000000003466 142.0
HKD2_k127_5672102_15 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000002645 150.0
HKD2_k127_5672102_16 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000001422 134.0
HKD2_k127_5672102_17 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000003401 113.0
HKD2_k127_5672102_18 Domain of unknown function (DUF4340) - - - 0.000002427 61.0
HKD2_k127_5672102_19 - - - - 0.000003341 55.0
HKD2_k127_5672102_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 454.0
HKD2_k127_5672102_20 - - - - 0.000004807 51.0
HKD2_k127_5672102_3 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 372.0
HKD2_k127_5672102_4 carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 337.0
HKD2_k127_5672102_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003571 281.0
HKD2_k127_5672102_6 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000008343 241.0
HKD2_k127_5672102_7 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000003006 245.0
HKD2_k127_5672102_8 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000002976 190.0
HKD2_k127_5672102_9 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000001586 186.0
HKD2_k127_5675558_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 454.0
HKD2_k127_5675558_1 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
HKD2_k127_5675558_2 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001069 250.0
HKD2_k127_5675558_3 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000002046 178.0
HKD2_k127_5675558_4 cytoskeletal protein binding - - - 0.00000000000000000000000000000004422 147.0
HKD2_k127_5675558_5 Domain of unknown function (DUF4215) - - - 0.0000000000004455 84.0
HKD2_k127_5675558_6 iron ion homeostasis K05349 - 3.2.1.21 0.00000000001937 76.0
HKD2_k127_5679110_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 466.0
HKD2_k127_5679110_1 CoA-transferase family III K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 448.0
HKD2_k127_5679110_10 SnoaL-like domain - - - 0.00000000000000000000000000000000001999 142.0
HKD2_k127_5679110_11 PFAM Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000001891 133.0
HKD2_k127_5679110_12 - - - - 0.0000000000000000000000000000005249 137.0
HKD2_k127_5679110_13 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000001877 119.0
HKD2_k127_5679110_14 Protein of unknown function (DUF541) K09807 - - 0.000000000000000003486 97.0
HKD2_k127_5679110_15 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000001054 65.0
HKD2_k127_5679110_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 389.0
HKD2_k127_5679110_3 Phosphoesterase family K01114 - 3.1.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005675 292.0
HKD2_k127_5679110_4 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009063 256.0
HKD2_k127_5679110_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001207 244.0
HKD2_k127_5679110_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000273 256.0
HKD2_k127_5679110_7 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000001056 205.0
HKD2_k127_5679110_8 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000007086 149.0
HKD2_k127_5679110_9 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000009004 158.0
HKD2_k127_5683_0 PFAM luciferase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 354.0
HKD2_k127_5683_1 peptide deformylase activity K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000004489 245.0
HKD2_k127_5683_2 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000005302 132.0
HKD2_k127_5683_3 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000001312 75.0
HKD2_k127_5683_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0002964 44.0
HKD2_k127_5708998_0 topoisomerase K02469 - 5.99.1.3 8.939e-254 804.0
HKD2_k127_5708998_1 DNA topoisomerase K02470,K02622 - 5.99.1.3 2.63e-251 793.0
HKD2_k127_5708998_2 RecQ zinc-binding K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 565.0
HKD2_k127_5708998_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 461.0
HKD2_k127_5708998_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 388.0
HKD2_k127_5708998_6 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.00000000000000000000000001048 117.0
HKD2_k127_5708998_7 Phosphorylase superfamily - - - 0.000001025 56.0
HKD2_k127_5807409_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.71e-200 653.0
HKD2_k127_5807409_1 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 396.0
HKD2_k127_5807409_2 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 306.0
HKD2_k127_5807409_3 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000001186 190.0
HKD2_k127_5807409_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000002266 109.0
HKD2_k127_5807409_5 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000001092 100.0
HKD2_k127_5807409_6 PKD domain K19668 - 3.2.1.91 0.000000000001034 74.0
HKD2_k127_5807409_7 bacterial-type flagellum-dependent cell motility K01317 - 3.4.21.10 0.000000006868 66.0
HKD2_k127_5807409_8 Homologues of snake disintegrins - - - 0.00001071 56.0
HKD2_k127_5807409_9 GAF domain - - - 0.0002255 55.0
HKD2_k127_5856779_0 alcohol dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 336.0
HKD2_k127_5856779_1 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000001485 246.0
HKD2_k127_5856779_2 Methylamine dehydrogenase light chain - - - 0.0000000000000000000000000000000000000000000000000000000000000007479 237.0
HKD2_k127_5856779_3 Methylamine dehydrogenase accessory protein MauD - - - 0.00000000000000000000000000000000000000000000000000000000000009227 227.0
HKD2_k127_5856779_4 Cytochrome c - - - 0.0000000000000000000000000000436 132.0
HKD2_k127_5856779_5 Methylamine utilisation protein MauE - - - 0.00000000000000000164 100.0
HKD2_k127_5856779_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000615 87.0
HKD2_k127_5856779_7 metalloendopeptidase activity K06261,K08867,K09187,K14972,K20371 - 2.1.1.43,2.7.11.1 0.000000000000006571 86.0
HKD2_k127_598374_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 486.0
HKD2_k127_598374_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000002445 250.0
HKD2_k127_598374_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000001906 233.0
HKD2_k127_598374_3 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000009324 97.0
HKD2_k127_6052693_0 Transmembrane secretion effector - - - 2.47e-259 812.0
HKD2_k127_6052693_1 ABC transporter K06020 - 3.6.3.25 2.945e-255 797.0
HKD2_k127_6052693_10 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 430.0
HKD2_k127_6052693_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 399.0
HKD2_k127_6052693_12 electron transfer activity K00428 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 383.0
HKD2_k127_6052693_13 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 384.0
HKD2_k127_6052693_14 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 359.0
HKD2_k127_6052693_15 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 328.0
HKD2_k127_6052693_16 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 337.0
HKD2_k127_6052693_17 'glutamate synthase K00123,K00317,K00528,K09835 - 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 330.0
HKD2_k127_6052693_18 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 317.0
HKD2_k127_6052693_19 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 306.0
HKD2_k127_6052693_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.099e-210 664.0
HKD2_k127_6052693_20 molybdenum ion binding K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003888 284.0
HKD2_k127_6052693_21 Acetyl-CoA dehydrogenase C-terminal like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003605 291.0
HKD2_k127_6052693_22 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002406 271.0
HKD2_k127_6052693_23 Uncharacterized protein conserved in bacteria (DUF2332) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004555 285.0
HKD2_k127_6052693_24 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003841 248.0
HKD2_k127_6052693_25 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000001164 237.0
HKD2_k127_6052693_26 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000005167 224.0
HKD2_k127_6052693_27 glutathione transferase activity K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000001563 228.0
HKD2_k127_6052693_28 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000001453 216.0
HKD2_k127_6052693_29 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000002179 209.0
HKD2_k127_6052693_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.389e-200 630.0
HKD2_k127_6052693_30 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000000000000000000000000000000003426 222.0
HKD2_k127_6052693_31 MaoC like domain K18290 - 4.2.1.56 0.00000000000000000000000000000000000000000000000000000005069 222.0
HKD2_k127_6052693_32 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000007204 199.0
HKD2_k127_6052693_33 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.00000000000000000000000000000000000000000000000005354 197.0
HKD2_k127_6052693_34 Pfam:PNPOx_C K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000001005 187.0
HKD2_k127_6052693_35 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000001922 188.0
HKD2_k127_6052693_36 2-oxoglutarate dehydrogenase K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000001698 166.0
HKD2_k127_6052693_37 Acyl-CoA dehydrogenase family member 10 K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000116 177.0
HKD2_k127_6052693_38 Tyrosine phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000156 168.0
HKD2_k127_6052693_39 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000001093 164.0
HKD2_k127_6052693_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 558.0
HKD2_k127_6052693_40 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000004643 146.0
HKD2_k127_6052693_41 - - - - 0.000000000000000000000000000004013 131.0
HKD2_k127_6052693_42 serine-type endopeptidase activity K20276 - - 0.00000000000000000000000005288 125.0
HKD2_k127_6052693_43 Pfam:RRM_6 - - - 0.000000000000000000000000188 110.0
HKD2_k127_6052693_44 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000001248 105.0
HKD2_k127_6052693_45 Methyltransferase - - - 0.000000000000000001057 96.0
HKD2_k127_6052693_46 Putative exonuclease, RdgC K03554 - - 0.000000000000000103 93.0
HKD2_k127_6052693_47 Putative exonuclease, RdgC K03554 - - 0.0000000000000006141 88.0
HKD2_k127_6052693_48 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000003989 79.0
HKD2_k127_6052693_49 Belongs to the frataxin family K06202,K19054 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 1.16.3.1 0.0000000000001712 76.0
HKD2_k127_6052693_5 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 545.0
HKD2_k127_6052693_50 heat shock protein binding - - - 0.0000000000009374 78.0
HKD2_k127_6052693_51 Copper type II ascorbate-dependent monooxygenase, C-terminal domain - - - 0.000000001381 70.0
HKD2_k127_6052693_52 transcriptional regulator K09017 - - 0.0001125 55.0
HKD2_k127_6052693_6 acyl-CoA dehydrogenase K00257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 538.0
HKD2_k127_6052693_7 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 514.0
HKD2_k127_6052693_8 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 462.0
HKD2_k127_6052693_9 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 462.0
HKD2_k127_6109631_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 545.0
HKD2_k127_6109631_1 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 499.0
HKD2_k127_6109631_10 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 314.0
HKD2_k127_6109631_11 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 302.0
HKD2_k127_6109631_12 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002152 254.0
HKD2_k127_6109631_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002577 251.0
HKD2_k127_6109631_14 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001838 250.0
HKD2_k127_6109631_15 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000001562 208.0
HKD2_k127_6109631_16 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000002326 199.0
HKD2_k127_6109631_17 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000007834 196.0
HKD2_k127_6109631_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000663 173.0
HKD2_k127_6109631_19 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000002787 166.0
HKD2_k127_6109631_2 Sulfite reductase K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 511.0
HKD2_k127_6109631_20 TIGRFAM geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000003924 172.0
HKD2_k127_6109631_21 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000005507 166.0
HKD2_k127_6109631_22 Thioredoxin - - - 0.000000000000000000000000000000000000006048 154.0
HKD2_k127_6109631_23 Outer membrane protein beta-barrel domain - - - 0.000000000000000000000000000000001195 138.0
HKD2_k127_6109631_24 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000007814 129.0
HKD2_k127_6109631_25 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000001948 133.0
HKD2_k127_6109631_26 COG0183 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000002911 106.0
HKD2_k127_6109631_27 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000001256 111.0
HKD2_k127_6109631_28 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000001017 104.0
HKD2_k127_6109631_29 - - - - 0.000007447 57.0
HKD2_k127_6109631_3 Pyruvate dehydrogenase K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 421.0
HKD2_k127_6109631_4 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 426.0
HKD2_k127_6109631_5 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 397.0
HKD2_k127_6109631_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 367.0
HKD2_k127_6109631_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 342.0
HKD2_k127_6109631_8 e3 binding domain K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 341.0
HKD2_k127_6109631_9 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 325.0
HKD2_k127_6139493_0 ABC transporter ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000004145 252.0
HKD2_k127_6139493_1 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000001819 231.0
HKD2_k127_6139493_2 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000009592 225.0
HKD2_k127_6139493_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000004855 174.0
HKD2_k127_6139493_4 Penicillin amidase - - - 0.0000000000000000000000000000000000004126 149.0
HKD2_k127_6139493_5 intermembrane phospholipid transfer K07323 - - 0.00000000001987 77.0
HKD2_k127_6158554_0 PFAM glycosyl transferase family 35 K00688 - 2.4.1.1 2.944e-194 619.0
HKD2_k127_6158554_1 Methyltransferase small domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 459.0
HKD2_k127_6158554_10 Hep Hag repeat protein - - - 0.00000000000000000001176 104.0
HKD2_k127_6158554_2 Belongs to the thiolase family K00632 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 444.0
HKD2_k127_6158554_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 323.0
HKD2_k127_6158554_4 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 314.0
HKD2_k127_6158554_5 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
HKD2_k127_6158554_6 Polysaccharide lyase family 4, domain II - - - 0.00000000000000000000000000000000000000000000000000002247 198.0
HKD2_k127_6158554_7 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000002668 189.0
HKD2_k127_6158554_8 membrane - - - 0.00000000000000000000000000000000000003798 153.0
HKD2_k127_6158554_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000001374 136.0
HKD2_k127_6350301_0 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0019904,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 522.0
HKD2_k127_6350301_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 409.0
HKD2_k127_6350301_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 362.0
HKD2_k127_6350301_3 Methyltransferase, chemotaxis proteins K00575 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004092 279.0
HKD2_k127_6350301_4 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
HKD2_k127_6350301_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K03408 - - 0.000000000000000000000000000000000000000000000792 170.0
HKD2_k127_6350301_6 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411,K03412 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0044403,GO:0044419,GO:0050896,GO:0051701,GO:0051704,GO:0052116,GO:0052126,GO:0052127,GO:0052143,GO:0052192,GO:0052195,GO:0052216,GO:0052243 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000005858 156.0
HKD2_k127_6350301_7 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000001649 144.0
HKD2_k127_6350301_8 cheY-homologous receiver domain K03413 - - 0.00000000000000000000003759 117.0
HKD2_k127_6350301_9 Chemotaxis phosphatase CheX K03409 - - 0.00000004955 64.0
HKD2_k127_6379603_0 Sodium:sulfate symporter transmembrane region K03319,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 415.0
HKD2_k127_6379603_1 Serine dehydrogenase proteinase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 349.0
HKD2_k127_6379603_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000001575 120.0
HKD2_k127_6379603_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000003317 126.0
HKD2_k127_6379603_4 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.00000000005176 72.0
HKD2_k127_6388920_0 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 527.0
HKD2_k127_6388920_1 - K22017 GO:0001894,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005102,GO:0005176,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007586,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010669,GO:0012505,GO:0016020,GO:0016021,GO:0016266,GO:0019538,GO:0022600,GO:0023052,GO:0030197,GO:0030277,GO:0031012,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0034645,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048871,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0071704,GO:0071944,GO:0080134,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002728 306.0
HKD2_k127_6388920_10 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000499 115.0
HKD2_k127_6388920_11 - - - - 0.00000000000000000000002122 108.0
HKD2_k127_6388920_12 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000001571 110.0
HKD2_k127_6388920_13 component of anaerobic - - - 0.0000000819 64.0
HKD2_k127_6388920_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002871 235.0
HKD2_k127_6388920_3 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.000000000000000000000000000000000000000000000000000000009936 217.0
HKD2_k127_6388920_4 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000002297 205.0
HKD2_k127_6388920_5 tRNA rRNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000000006877 194.0
HKD2_k127_6388920_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000002765 158.0
HKD2_k127_6388920_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000008565 158.0
HKD2_k127_6388920_8 Flagellar filament outer layer protein Flaa - - - 0.0000000000000000000000000000000000000001471 171.0
HKD2_k127_6388920_9 NUDIX domain - - - 0.00000000000000000000000000000000006716 149.0
HKD2_k127_6399529_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 278.0
HKD2_k127_6399529_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002736 284.0
HKD2_k127_6399529_2 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007633 279.0
HKD2_k127_6399529_3 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000003235 183.0
HKD2_k127_6399529_4 Protease prsW family - - - 0.00000000002529 73.0
HKD2_k127_6399529_5 - - - - 0.0000000145 61.0
HKD2_k127_6400830_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1448.0
HKD2_k127_6400830_1 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 332.0
HKD2_k127_6400830_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 315.0
HKD2_k127_6400830_3 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000001179 187.0
HKD2_k127_6400830_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000005628 122.0
HKD2_k127_6400830_5 - - - - 0.00000000000000000007293 104.0
HKD2_k127_6440761_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 506.0
HKD2_k127_6440761_1 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 398.0
HKD2_k127_6440761_2 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 319.0
HKD2_k127_6440761_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000212 283.0
HKD2_k127_6440761_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000003972 173.0
HKD2_k127_6440761_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000002257 102.0
HKD2_k127_6440761_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.000000002089 69.0
HKD2_k127_6452515_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 1.023e-304 950.0
HKD2_k127_6452515_1 Circularly permuted ATP-grasp type 2 - - - 3.421e-251 803.0
HKD2_k127_6452515_10 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 348.0
HKD2_k127_6452515_11 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 337.0
HKD2_k127_6452515_12 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 334.0
HKD2_k127_6452515_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 322.0
HKD2_k127_6452515_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 312.0
HKD2_k127_6452515_15 Bacterial transglutaminase-like N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002939 312.0
HKD2_k127_6452515_16 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004496 270.0
HKD2_k127_6452515_17 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000002123 232.0
HKD2_k127_6452515_18 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000000000000007477 212.0
HKD2_k127_6452515_19 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000001003 181.0
HKD2_k127_6452515_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 2.164e-226 737.0
HKD2_k127_6452515_20 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000001053 184.0
HKD2_k127_6452515_21 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000004056 173.0
HKD2_k127_6452515_22 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000002041 181.0
HKD2_k127_6452515_23 Phosphate acyltransferases - - - 0.000000000000000000001079 111.0
HKD2_k127_6452515_24 Putative amidoligase enzyme (DUF2126) - - - 0.000000000000001192 80.0
HKD2_k127_6452515_25 Fe-S oxidoreductase - - - 0.00000000004476 70.0
HKD2_k127_6452515_26 ig-like, plexins, transcription factors - - - 0.00000001698 68.0
HKD2_k127_6452515_27 - - - - 0.00000002 62.0
HKD2_k127_6452515_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 5.037e-221 752.0
HKD2_k127_6452515_4 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 615.0
HKD2_k127_6452515_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 550.0
HKD2_k127_6452515_6 alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 542.0
HKD2_k127_6452515_7 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 468.0
HKD2_k127_6452515_8 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 410.0
HKD2_k127_6452515_9 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 363.0
HKD2_k127_6455117_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1427.0
HKD2_k127_6455117_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.847e-214 685.0
HKD2_k127_6455117_10 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000003115 220.0
HKD2_k127_6455117_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000002229 206.0
HKD2_k127_6455117_12 Methylmalonyl-CoA mutase K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000007746 205.0
HKD2_k127_6455117_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000003822 182.0
HKD2_k127_6455117_14 Outer membrane efflux protein - - - 0.000000000000000000000000000000000008784 152.0
HKD2_k127_6455117_2 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 481.0
HKD2_k127_6455117_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 454.0
HKD2_k127_6455117_4 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 369.0
HKD2_k127_6455117_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 305.0
HKD2_k127_6455117_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000003212 261.0
HKD2_k127_6455117_7 proposed homoserine kinase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000003531 265.0
HKD2_k127_6455117_8 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002462 271.0
HKD2_k127_6455117_9 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004921 240.0
HKD2_k127_646052_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 336.0
HKD2_k127_646052_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000158 293.0
HKD2_k127_646052_10 MgtE intracellular N domain - - - 0.0004623 46.0
HKD2_k127_646052_2 Cellulose biosynthesis protein BcsQ K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000281 241.0
HKD2_k127_646052_3 sigma factor activity K02405,K03093 - - 0.000000000000000000000000000000000000000000000000000000000007073 229.0
HKD2_k127_646052_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000001922 193.0
HKD2_k127_646052_5 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.00000000000000000000000000000000000000001707 166.0
HKD2_k127_646052_6 Flagellar motor switch protein FliN K02417 - - 0.000000000000000000000000003815 125.0
HKD2_k127_646052_7 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000000000000000000007151 102.0
HKD2_k127_646052_8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006109,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016071,GO:0019222,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000006496 79.0
HKD2_k127_646052_9 flagellar K02404 - - 0.0000000000001427 83.0
HKD2_k127_6493670_0 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 410.0
HKD2_k127_6493670_1 Cytochrome P450 K15981 - 1.14.13.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 362.0
HKD2_k127_6493670_2 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 372.0
HKD2_k127_6493670_3 MAPEG family - - - 0.00000000000000000000000000000000000004548 155.0
HKD2_k127_6493670_4 Limonene-1,2-epoxide hydrolase K10533 - 3.3.2.8 0.0000000000000000000000000001531 133.0
HKD2_k127_6493670_5 Methyltransferase domain - - - 0.00000003759 66.0
HKD2_k127_6495540_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 1.68e-239 752.0
HKD2_k127_6495540_1 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 631.0
HKD2_k127_6495540_11 - - - - 0.0000000000000000000000007327 119.0
HKD2_k127_6495540_12 protein possibly involved in aromatic compounds catabolism - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000002851 63.0
HKD2_k127_6495540_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0009594 44.0
HKD2_k127_6495540_2 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 349.0
HKD2_k127_6495540_3 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 314.0
HKD2_k127_6495540_4 DTW K05812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002553 266.0
HKD2_k127_6495540_5 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000102 259.0
HKD2_k127_6495540_6 MatE - - - 0.00000000000000000000000000000000000000000000000000000000001026 227.0
HKD2_k127_6495540_7 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000004398 218.0
HKD2_k127_6495540_8 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000007012 192.0
HKD2_k127_6495540_9 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000001794 168.0
HKD2_k127_6511458_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000001381 186.0
HKD2_k127_6511458_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000001266 145.0
HKD2_k127_6536012_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 587.0
HKD2_k127_6536012_1 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 587.0
HKD2_k127_6536012_10 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001573 252.0
HKD2_k127_6536012_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000001682 199.0
HKD2_k127_6536012_12 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000001589 176.0
HKD2_k127_6536012_13 PFAM NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000000008357 164.0
HKD2_k127_6536012_14 - - - - 0.000000000000000000000000000000000000005539 162.0
HKD2_k127_6536012_15 tetR family - - - 0.0000000000000000000000000000001155 134.0
HKD2_k127_6536012_16 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000005058 106.0
HKD2_k127_6536012_17 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000002662 106.0
HKD2_k127_6536012_18 Membrane bound O-acyl transferase MBOAT family protein K03739,K19294 - - 0.00000000000000000000007492 114.0
HKD2_k127_6536012_19 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000005491 104.0
HKD2_k127_6536012_2 PFAM Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 520.0
HKD2_k127_6536012_20 Molydopterin dinucleotide binding domain - - - 0.00000000000000001279 97.0
HKD2_k127_6536012_21 Thioesterase - - - 0.00000000000000005409 94.0
HKD2_k127_6536012_22 transcriptional - - - 0.00000000000002159 87.0
HKD2_k127_6536012_23 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000005092 75.0
HKD2_k127_6536012_24 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000001372 68.0
HKD2_k127_6536012_3 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 392.0
HKD2_k127_6536012_4 COG2513 PEP phosphonomutase and related enzymes K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 379.0
HKD2_k127_6536012_5 Acyl-CoA dehydrogenase, C-terminal domain K16047 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006694,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009056,GO:0009058,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016712,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044238,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046164,GO:0048037,GO:0050660,GO:0050662,GO:0051704,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1902652 1.14.14.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 381.0
HKD2_k127_6536012_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 298.0
HKD2_k127_6536012_7 Amidohydrolase K03392 - 4.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 309.0
HKD2_k127_6536012_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 290.0
HKD2_k127_6536012_9 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002249 282.0
HKD2_k127_6547816_0 CoA binding domain - - - 2.831e-241 788.0
HKD2_k127_6547816_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 375.0
HKD2_k127_6547816_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000002445 136.0
HKD2_k127_6547816_11 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000003407 136.0
HKD2_k127_6547816_12 - - - - 0.000000000006334 72.0
HKD2_k127_6547816_2 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 369.0
HKD2_k127_6547816_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 354.0
HKD2_k127_6547816_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 317.0
HKD2_k127_6547816_5 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000001083 209.0
HKD2_k127_6547816_6 - - - - 0.000000000000000000000000000000000001254 160.0
HKD2_k127_6547816_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000001513 144.0
HKD2_k127_6547816_8 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000001771 143.0
HKD2_k127_6547816_9 PFAM class II aldolase adducin family protein K01628,K03077 - 4.1.2.17,5.1.3.4 0.000000000000000000000000000001906 128.0
HKD2_k127_6559674_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1050.0
HKD2_k127_6559674_1 elongation factor Tu domain 2 protein K02355 - - 2.259e-237 752.0
HKD2_k127_6559674_10 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 372.0
HKD2_k127_6559674_11 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 385.0
HKD2_k127_6559674_12 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 349.0
HKD2_k127_6559674_13 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 346.0
HKD2_k127_6559674_14 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 343.0
HKD2_k127_6559674_15 PFAM ABC transporter related K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 335.0
HKD2_k127_6559674_16 methyltransferase K00563,K07112 - 2.1.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 317.0
HKD2_k127_6559674_17 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 307.0
HKD2_k127_6559674_18 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 326.0
HKD2_k127_6559674_19 Radical SAM superfamily K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 314.0
HKD2_k127_6559674_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.349e-234 735.0
HKD2_k127_6559674_20 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006523 276.0
HKD2_k127_6559674_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002728 278.0
HKD2_k127_6559674_22 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004127 276.0
HKD2_k127_6559674_23 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000007812 265.0
HKD2_k127_6559674_24 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000009052 262.0
HKD2_k127_6559674_25 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001538 258.0
HKD2_k127_6559674_26 - K00241 - - 0.0000000000000000000000000000000000000000000000000000000000001852 218.0
HKD2_k127_6559674_28 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000003279 190.0
HKD2_k127_6559674_29 PFAM Glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000000000000000000004759 182.0
HKD2_k127_6559674_3 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 570.0
HKD2_k127_6559674_30 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000006498 188.0
HKD2_k127_6559674_31 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000007308 185.0
HKD2_k127_6559674_32 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000001066 182.0
HKD2_k127_6559674_33 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000001293 190.0
HKD2_k127_6559674_34 arylsulfatase A - - - 0.0000000000000000000000000000000000000000005406 174.0
HKD2_k127_6559674_35 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000009032 179.0
HKD2_k127_6559674_36 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000008482 168.0
HKD2_k127_6559674_37 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000001092 159.0
HKD2_k127_6559674_38 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000002362 150.0
HKD2_k127_6559674_39 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000006227 148.0
HKD2_k127_6559674_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 561.0
HKD2_k127_6559674_40 DoxX-like family - - - 0.000000000000000000000000000001341 134.0
HKD2_k127_6559674_41 - - - - 0.000000000000000000000000001415 121.0
HKD2_k127_6559674_42 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000004981 113.0
HKD2_k127_6559674_43 Thrombospondin type 3 repeat - - - 0.00000000000000000000004106 117.0
HKD2_k127_6559674_44 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000000000000000756 103.0
HKD2_k127_6559674_45 transferase activity, transferring glycosyl groups K20444 - - 0.00000000000000000005888 105.0
HKD2_k127_6559674_46 Bacterial transferase hexapeptide (six repeats) K21379 - 2.3.1.209 0.00000000000008566 83.0
HKD2_k127_6559674_48 - - - - 0.00000000001491 72.0
HKD2_k127_6559674_49 GDSL-like Lipase/Acylhydrolase family - - - 0.000000002587 66.0
HKD2_k127_6559674_5 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 520.0
HKD2_k127_6559674_50 PspC domain - - - 0.00001966 52.0
HKD2_k127_6559674_51 EamA-like transporter family - - - 0.00003609 55.0
HKD2_k127_6559674_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 492.0
HKD2_k127_6559674_7 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 490.0
HKD2_k127_6559674_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 426.0
HKD2_k127_6559674_9 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 414.0
HKD2_k127_6572182_0 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 413.0
HKD2_k127_6572182_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 419.0
HKD2_k127_6572182_2 cytochrome P-450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 362.0
HKD2_k127_6572182_3 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 339.0
HKD2_k127_6572182_4 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 324.0
HKD2_k127_6572182_5 Enoyl-(Acyl carrier protein) reductase K15734 - 1.1.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005381 274.0
HKD2_k127_6572182_6 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000004028 220.0
HKD2_k127_6572182_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000007138 196.0
HKD2_k127_6572182_8 PFAM Peptidase M11 gametolysin - - - 0.000000000000000000001602 111.0
HKD2_k127_6572182_9 Protein-disulfide isomerase - - - 0.000000000000001233 90.0
HKD2_k127_6593806_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000005043 216.0
HKD2_k127_6593806_1 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000001733 164.0
HKD2_k127_6593806_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000001188 105.0
HKD2_k127_6640823_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 489.0
HKD2_k127_6640823_1 YdjC-like protein K03478 - 3.5.1.105 0.000002986 50.0
HKD2_k127_6646502_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1065.0
HKD2_k127_6646502_1 (ABC) transporter K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 587.0
HKD2_k127_6646502_10 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000000000000000056 175.0
HKD2_k127_6646502_11 Transcriptional regulator K13771,K13772 - - 0.00000000000000000000000000000000000000005915 163.0
HKD2_k127_6646502_12 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000001208 153.0
HKD2_k127_6646502_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000002806 117.0
HKD2_k127_6646502_14 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000000003701 102.0
HKD2_k127_6646502_15 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 - - 0.00000000000000000007047 94.0
HKD2_k127_6646502_2 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 466.0
HKD2_k127_6646502_3 enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 369.0
HKD2_k127_6646502_4 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 318.0
HKD2_k127_6646502_5 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008433 280.0
HKD2_k127_6646502_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000006989 225.0
HKD2_k127_6646502_7 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
HKD2_k127_6646502_8 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000004953 201.0
HKD2_k127_6646502_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000005562 173.0
HKD2_k127_6652685_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.072e-211 677.0
HKD2_k127_6652685_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002638 273.0
HKD2_k127_6654609_0 secondary active sulfate transmembrane transporter activity K06901 - - 2.486e-221 698.0
HKD2_k127_6654609_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 585.0
HKD2_k127_6654609_10 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000003854 204.0
HKD2_k127_6654609_11 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000007484 204.0
HKD2_k127_6654609_12 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000001049 220.0
HKD2_k127_6654609_13 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000003049 193.0
HKD2_k127_6654609_14 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000001022 127.0
HKD2_k127_6654609_15 ABC transporter substrate-binding protein K02067 - - 0.00000000000000000000000000002175 133.0
HKD2_k127_6654609_16 PFAM toluene tolerance K07323 - - 0.0000000000000000000000000001113 123.0
HKD2_k127_6654609_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 556.0
HKD2_k127_6654609_3 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 381.0
HKD2_k127_6654609_4 Electron transfer flavoprotein, beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 300.0
HKD2_k127_6654609_5 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 302.0
HKD2_k127_6654609_6 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001468 276.0
HKD2_k127_6654609_7 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000009749 261.0
HKD2_k127_6654609_8 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 256.0
HKD2_k127_6654609_9 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000002747 227.0
HKD2_k127_6658803_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.317e-216 687.0
HKD2_k127_6658803_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 544.0
HKD2_k127_6658803_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000006005 115.0
HKD2_k127_6658803_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 444.0
HKD2_k127_6658803_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 389.0
HKD2_k127_6658803_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 362.0
HKD2_k127_6658803_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 306.0
HKD2_k127_6658803_6 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000001676 242.0
HKD2_k127_6658803_7 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000006352 225.0
HKD2_k127_6658803_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000002291 202.0
HKD2_k127_6658803_9 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000003356 187.0
HKD2_k127_6719945_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001047 273.0
HKD2_k127_6719945_1 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000003027 160.0
HKD2_k127_6719945_2 PFAM Polysaccharide export protein - - - 0.000000000000000000000000000000002135 139.0
HKD2_k127_6719945_3 PFAM lipopolysaccharide biosynthesis - - - 0.0000000000000000000000000000003484 140.0
HKD2_k127_6719945_4 AAA domain K08252 - 2.7.10.1 0.0000000000000000006232 97.0
HKD2_k127_6719945_5 O-Antigen ligase - - - 0.00002497 57.0
HKD2_k127_6738684_0 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 4.414e-237 761.0
HKD2_k127_6738684_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 417.0
HKD2_k127_6738684_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 368.0
HKD2_k127_6738684_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 331.0
HKD2_k127_6738684_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 315.0
HKD2_k127_6738684_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005741 308.0
HKD2_k127_6738684_6 fatty acid hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001156 239.0
HKD2_k127_6738684_7 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000000000000000000000000000000000000000000000002731 233.0
HKD2_k127_6738684_8 peptidyl-tyrosine sulfation - - - 0.000000000000000000000004221 108.0
HKD2_k127_6738684_9 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000474 99.0
HKD2_k127_6804766_0 Dehydrogenase E1 component K00164 - 1.2.4.2 7.128e-254 807.0
HKD2_k127_6804766_1 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 606.0
HKD2_k127_6827220_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 418.0
HKD2_k127_6827220_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000001888 205.0
HKD2_k127_6827220_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000004771 143.0
HKD2_k127_6916777_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1025.0
HKD2_k127_6916777_1 Amino acid permease - - - 2.732e-205 655.0
HKD2_k127_6916777_2 Amino acid permease - - - 3.972e-205 672.0
HKD2_k127_6916777_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.632e-203 668.0
HKD2_k127_6916777_4 Response regulator, receiver K11384 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 369.0
HKD2_k127_6916777_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000002269 246.0
HKD2_k127_6916777_6 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000002531 170.0
HKD2_k127_6916777_7 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000002763 93.0
HKD2_k127_6948411_0 6-phosphogluconolactonase activity - - - 4.182e-278 873.0
HKD2_k127_6948411_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.712e-220 699.0
HKD2_k127_6948411_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002838 274.0
HKD2_k127_6948411_3 protein Rv3762c - Mycobacterium tuberculosis - - - 0.000000000000000000000000000000000000000000000000000000007065 205.0
HKD2_k127_6948411_4 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000006709 154.0
HKD2_k127_6948411_5 Alkyl sulfatase dimerisation - - - 0.000000004619 57.0
HKD2_k127_6972385_0 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 365.0
HKD2_k127_6972385_1 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 332.0
HKD2_k127_6972385_2 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000001602 164.0
HKD2_k127_6972385_3 phospholipase C K01114 - 3.1.4.3 0.000000000000000000000000000000000000002577 150.0
HKD2_k127_6972385_4 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000001447 134.0
HKD2_k127_6972385_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000001449 50.0
HKD2_k127_6981417_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 468.0
HKD2_k127_6981417_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 431.0
HKD2_k127_6981417_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000001755 265.0
HKD2_k127_6981417_11 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000009781 239.0
HKD2_k127_6981417_12 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000236 236.0
HKD2_k127_6981417_13 transport system involved in gliding motility, auxiliary component - - - 0.0000000000000000000000000000000000000000000000000000000000932 223.0
HKD2_k127_6981417_14 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000003143 199.0
HKD2_k127_6981417_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000001359 212.0
HKD2_k127_6981417_16 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000001825 211.0
HKD2_k127_6981417_17 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000002707 204.0
HKD2_k127_6981417_18 - K01992 - - 0.000000000000000000000000000000000000000000000001481 192.0
HKD2_k127_6981417_19 Fibronectin fibrinogen-binding protein - - - 0.0000000000000000000000000000000000000000000000962 175.0
HKD2_k127_6981417_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 417.0
HKD2_k127_6981417_20 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000005001 153.0
HKD2_k127_6981417_21 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000001051 147.0
HKD2_k127_6981417_22 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000001394 135.0
HKD2_k127_6981417_23 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000006686 132.0
HKD2_k127_6981417_24 chlorophyll binding - - - 0.00000000000000001954 98.0
HKD2_k127_6981417_25 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0003761 47.0
HKD2_k127_6981417_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 385.0
HKD2_k127_6981417_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 319.0
HKD2_k127_6981417_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 316.0
HKD2_k127_6981417_6 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 315.0
HKD2_k127_6981417_7 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 299.0
HKD2_k127_6981417_8 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008052 299.0
HKD2_k127_6981417_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004436 264.0
HKD2_k127_7111850_0 PFAM sodium calcium exchanger membrane region K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 428.0
HKD2_k127_7111850_1 LysR family transcription regulator protein - - - 0.000000000000000000004145 95.0
HKD2_k127_7124175_0 Ammonium Transporter Family K03320 - - 2.355e-260 814.0
HKD2_k127_7124175_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 492.0
HKD2_k127_7124175_10 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 413.0
HKD2_k127_7124175_11 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 383.0
HKD2_k127_7124175_12 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 345.0
HKD2_k127_7124175_13 cytochrome p450 - GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 335.0
HKD2_k127_7124175_14 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 366.0
HKD2_k127_7124175_15 lipid-transfer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 338.0
HKD2_k127_7124175_16 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 350.0
HKD2_k127_7124175_17 2-methylcitrate dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 340.0
HKD2_k127_7124175_18 PFAM luciferase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 314.0
HKD2_k127_7124175_19 Enoyl-(Acyl carrier protein) reductase - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 309.0
HKD2_k127_7124175_2 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 494.0
HKD2_k127_7124175_20 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003189 294.0
HKD2_k127_7124175_21 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000007152 255.0
HKD2_k127_7124175_22 Beta-lactamase K08869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002452 263.0
HKD2_k127_7124175_23 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000008767 263.0
HKD2_k127_7124175_24 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006745 265.0
HKD2_k127_7124175_25 Phosphoenolpyruvate phosphomutase K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000006478 249.0
HKD2_k127_7124175_26 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000007409 247.0
HKD2_k127_7124175_27 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000002948 227.0
HKD2_k127_7124175_28 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000001937 237.0
HKD2_k127_7124175_29 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000004546 241.0
HKD2_k127_7124175_3 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 483.0
HKD2_k127_7124175_30 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000001125 218.0
HKD2_k127_7124175_31 riboflavin synthase alpha chain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000001136 195.0
HKD2_k127_7124175_32 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.00000000000000000000000000000000000000000000000000005449 195.0
HKD2_k127_7124175_33 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000000002018 183.0
HKD2_k127_7124175_34 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000001385 171.0
HKD2_k127_7124175_35 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000001986 171.0
HKD2_k127_7124175_36 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000002327 171.0
HKD2_k127_7124175_38 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000002242 132.0
HKD2_k127_7124175_39 lipid-transfer protein - - - 0.00000000000000000000000000003439 136.0
HKD2_k127_7124175_4 cytochrome p450 K20497 - 1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 468.0
HKD2_k127_7124175_40 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000009878 112.0
HKD2_k127_7124175_42 Bacterial regulatory proteins, tetR family - - - 0.0000000000008975 77.0
HKD2_k127_7124175_43 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000006145 67.0
HKD2_k127_7124175_44 Sh3 type 3 domain protein - - - 0.00000001182 68.0
HKD2_k127_7124175_45 Histidine kinase - - - 0.00000001629 64.0
HKD2_k127_7124175_46 ATP-grasp - - - 0.00000157 56.0
HKD2_k127_7124175_47 Transcription factor zinc-finger K09981 - - 0.000007889 54.0
HKD2_k127_7124175_48 PFAM major facilitator superfamily MFS_1 - - - 0.00002193 57.0
HKD2_k127_7124175_49 Histidine kinase - - - 0.0001485 55.0
HKD2_k127_7124175_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 452.0
HKD2_k127_7124175_50 Outer membrane lipoprotein - - - 0.000267 54.0
HKD2_k127_7124175_6 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 447.0
HKD2_k127_7124175_7 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 437.0
HKD2_k127_7124175_8 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 425.0
HKD2_k127_7124175_9 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 415.0
HKD2_k127_7382649_0 Nitronate monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 344.0
HKD2_k127_7382649_1 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000002083 198.0
HKD2_k127_7382649_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000001466 199.0
HKD2_k127_7666094_0 ABC transporter K06147,K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 559.0
HKD2_k127_7666094_1 ABC transporter transmembrane region K06147,K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 468.0
HKD2_k127_7666094_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133,5.1.3.13 0.00000000000000000000000000000000000000000000000000000000002847 220.0
HKD2_k127_7666094_3 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000004592 201.0
HKD2_k127_7666094_4 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000002722 120.0
HKD2_k127_7666094_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000317 118.0
HKD2_k127_7699487_0 Cytochrome c-type biogenesis protein CcmF C-terminal K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 611.0
HKD2_k127_7699487_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 502.0
HKD2_k127_7699487_2 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 349.0
HKD2_k127_7699487_3 PFAM Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000003439 206.0
HKD2_k127_7699487_4 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000002462 219.0
HKD2_k127_7699487_5 PFAM ABC transporter related K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000001361 179.0
HKD2_k127_7699487_6 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000121 156.0
HKD2_k127_7699487_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000001371 121.0
HKD2_k127_7699487_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000002531 90.0
HKD2_k127_7699487_9 subunit of a heme lyase K02200 - - 0.000000000005913 79.0
HKD2_k127_7716805_0 Acyl-CoA dehydrogenase, C-terminal domain K00249,K11731 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 531.0
HKD2_k127_7716805_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 475.0
HKD2_k127_7716805_10 Periplasmic component of the Tol biopolymer transport system - - - 0.00001297 57.0
HKD2_k127_7716805_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0001289 56.0
HKD2_k127_7716805_2 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000002645 282.0
HKD2_k127_7716805_3 SAM-dependent RNA methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000003256 206.0
HKD2_k127_7716805_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000965 165.0
HKD2_k127_7716805_5 Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000001789 176.0
HKD2_k127_7716805_6 histidine kinase HAMP region domain protein K11527 - 2.7.13.3 0.000000000000000000000000000000000000000001843 178.0
HKD2_k127_7716805_7 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000006737 110.0
HKD2_k127_7716805_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000001744 99.0
HKD2_k127_7716805_9 KH domain K06960 - - 0.0000000000000000000002995 98.0
HKD2_k127_7748267_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 9.488e-194 625.0
HKD2_k127_7748267_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 580.0
HKD2_k127_7748267_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 371.0
HKD2_k127_7748267_11 Flagellar biogenesis master sigma-54-dependent transcriptional response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 350.0
HKD2_k127_7748267_12 Carboxypeptidase regulatory-like domain K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 372.0
HKD2_k127_7748267_13 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000983 348.0
HKD2_k127_7748267_14 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 327.0
HKD2_k127_7748267_15 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 289.0
HKD2_k127_7748267_16 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 314.0
HKD2_k127_7748267_17 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001282 285.0
HKD2_k127_7748267_18 O-methyltransferase K00588 - 2.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004248 275.0
HKD2_k127_7748267_19 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000003571 251.0
HKD2_k127_7748267_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 475.0
HKD2_k127_7748267_20 beta-N-acetylhexosaminidase activity K01197,K15719 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0030246,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 2.3.1.48,3.2.1.169,3.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000007177 258.0
HKD2_k127_7748267_21 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000002494 250.0
HKD2_k127_7748267_22 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000001404 215.0
HKD2_k127_7748267_23 KR domain K00059 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.1.100 0.00000000000000000000000000000000000000000000000000001901 199.0
HKD2_k127_7748267_24 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000001404 175.0
HKD2_k127_7748267_25 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000001932 165.0
HKD2_k127_7748267_26 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000002413 169.0
HKD2_k127_7748267_27 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000001173 152.0
HKD2_k127_7748267_28 Alpha beta hydrolase - - - 0.0000000000000000000000000001276 132.0
HKD2_k127_7748267_29 metal-dependent phosphohydrolase HD region K07814 - - 0.0000000000000000000000002024 121.0
HKD2_k127_7748267_3 cytochrome p450 K16046 - 1.14.13.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 451.0
HKD2_k127_7748267_30 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000004407 113.0
HKD2_k127_7748267_31 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.000000000000000000000002727 110.0
HKD2_k127_7748267_32 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000004533 108.0
HKD2_k127_7748267_33 Phospholipid methyltransferase - - - 0.00000000000000000000007536 109.0
HKD2_k127_7748267_34 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000176 93.0
HKD2_k127_7748267_35 COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000000003165 87.0
HKD2_k127_7748267_36 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.0000000000001065 84.0
HKD2_k127_7748267_37 - - - - 0.0000000003967 63.0
HKD2_k127_7748267_38 Domain of unknown function (DUF1508) K09946 - - 0.0002207 45.0
HKD2_k127_7748267_4 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 452.0
HKD2_k127_7748267_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 442.0
HKD2_k127_7748267_6 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 430.0
HKD2_k127_7748267_7 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 414.0
HKD2_k127_7748267_8 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 413.0
HKD2_k127_7748267_9 Coenzyme A transferase K01027,K01029,K01032 - 2.8.3.5,2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 391.0
HKD2_k127_7787712_0 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 551.0
HKD2_k127_7787712_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 475.0
HKD2_k127_7787712_10 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001565 290.0
HKD2_k127_7787712_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004575 275.0
HKD2_k127_7787712_12 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001593 269.0
HKD2_k127_7787712_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000005626 250.0
HKD2_k127_7787712_14 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005158 256.0
HKD2_k127_7787712_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000004612 219.0
HKD2_k127_7787712_16 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000001796 221.0
HKD2_k127_7787712_17 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000002875 204.0
HKD2_k127_7787712_18 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000161 193.0
HKD2_k127_7787712_19 - - - - 0.000000000000000000000000000002819 130.0
HKD2_k127_7787712_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 422.0
HKD2_k127_7787712_20 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000005033 128.0
HKD2_k127_7787712_21 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000006815 126.0
HKD2_k127_7787712_22 - - - - 0.000000000000000000000001119 109.0
HKD2_k127_7787712_23 Domain of unknown function (DUF4215) - - - 0.0000000000000000000000481 113.0
HKD2_k127_7787712_24 PFAM response regulator receiver - - - 0.0000000000000000000409 95.0
HKD2_k127_7787712_25 recA bacterial DNA recombination protein - - - 0.00000000000000032 87.0
HKD2_k127_7787712_26 Redoxin - - - 0.0000000004692 68.0
HKD2_k127_7787712_27 manganese ion transmembrane transporter activity - - - 0.0000000007909 72.0
HKD2_k127_7787712_28 Glycosyltransferase family 87 - - - 0.000001183 61.0
HKD2_k127_7787712_29 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000004304 54.0
HKD2_k127_7787712_3 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 398.0
HKD2_k127_7787712_30 Helix-turn-helix XRE-family like proteins - - - 0.00009669 54.0
HKD2_k127_7787712_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 388.0
HKD2_k127_7787712_5 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 376.0
HKD2_k127_7787712_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 382.0
HKD2_k127_7787712_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 351.0
HKD2_k127_7787712_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 340.0
HKD2_k127_7787712_9 PFAM response regulator receiver K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 283.0
HKD2_k127_7789416_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 456.0
HKD2_k127_7789416_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000002898 176.0
HKD2_k127_7789416_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000151 57.0
HKD2_k127_7794714_0 PFAM Glycoside hydrolase 15-related - - - 3.117e-295 943.0
HKD2_k127_7794714_1 Glycosyl transferase family 21 K03669 - - 8.614e-235 754.0
HKD2_k127_7794714_10 KR domain K07124 - - 0.00000000000000000000000000000000000000000000000000000004633 209.0
HKD2_k127_7794714_11 membrane - - - 0.000000000000000000000000000000000000000000002511 167.0
HKD2_k127_7794714_12 Dolichol kinase - - - 0.000000000000000000000000000000000000000000008724 177.0
HKD2_k127_7794714_2 Probably involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 511.0
HKD2_k127_7794714_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 412.0
HKD2_k127_7794714_4 ABC transporter substrate-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 413.0
HKD2_k127_7794714_5 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 374.0
HKD2_k127_7794714_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 376.0
HKD2_k127_7794714_7 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 325.0
HKD2_k127_7794714_8 carbohydrate binding K00702 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001346 285.0
HKD2_k127_7794714_9 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001634 269.0
HKD2_k127_7797363_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.06e-295 928.0
HKD2_k127_7797363_1 Belongs to the ClpA ClpB family K03694 - - 4.991e-292 914.0
HKD2_k127_7797363_10 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 392.0
HKD2_k127_7797363_11 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 383.0
HKD2_k127_7797363_12 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 353.0
HKD2_k127_7797363_13 PFAM CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 359.0
HKD2_k127_7797363_14 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 375.0
HKD2_k127_7797363_15 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 344.0
HKD2_k127_7797363_16 PFAM alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 337.0
HKD2_k127_7797363_17 NAD(P)H quinone oxidoreductase, PIG3 family K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 329.0
HKD2_k127_7797363_18 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01885,K01894 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 316.0
HKD2_k127_7797363_19 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 317.0
HKD2_k127_7797363_2 Belongs to the thiolase family K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 1.582e-194 617.0
HKD2_k127_7797363_20 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 333.0
HKD2_k127_7797363_21 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006118 285.0
HKD2_k127_7797363_22 ABC-type glycine betaine transport system K05845 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006338 274.0
HKD2_k127_7797363_23 SMART ATPase, AAA type, core K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001404 264.0
HKD2_k127_7797363_24 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000397 257.0
HKD2_k127_7797363_25 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000003669 258.0
HKD2_k127_7797363_26 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000002024 245.0
HKD2_k127_7797363_27 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000003259 226.0
HKD2_k127_7797363_28 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000000000001045 221.0
HKD2_k127_7797363_29 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000004777 223.0
HKD2_k127_7797363_3 DEAD-like helicases superfamily K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 626.0
HKD2_k127_7797363_30 KR domain - - - 0.000000000000000000000000000000000000000000000000000001505 217.0
HKD2_k127_7797363_31 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000003796 213.0
HKD2_k127_7797363_32 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000275 190.0
HKD2_k127_7797363_33 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000005075 204.0
HKD2_k127_7797363_34 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000003421 175.0
HKD2_k127_7797363_35 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000004893 171.0
HKD2_k127_7797363_36 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000005225 160.0
HKD2_k127_7797363_37 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000001638 148.0
HKD2_k127_7797363_38 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.00000000000000000000000000000000000004438 166.0
HKD2_k127_7797363_39 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000022 157.0
HKD2_k127_7797363_4 Glutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 588.0
HKD2_k127_7797363_40 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000007775 147.0
HKD2_k127_7797363_41 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000002523 127.0
HKD2_k127_7797363_42 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000005919 130.0
HKD2_k127_7797363_43 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000001687 121.0
HKD2_k127_7797363_44 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000005417 127.0
HKD2_k127_7797363_45 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000794 99.0
HKD2_k127_7797363_46 - - - - 0.0000000000000000000008421 110.0
HKD2_k127_7797363_47 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.00000000000000000000502 109.0
HKD2_k127_7797363_48 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000006919 107.0
HKD2_k127_7797363_49 Glycogen recognition site of AMP-activated protein kinase - - - 0.000000000000000002473 100.0
HKD2_k127_7797363_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 579.0
HKD2_k127_7797363_50 Pfam SNARE associated Golgi protein - - - 0.000000000000000003769 98.0
HKD2_k127_7797363_51 translation initiation factor activity K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000008877 86.0
HKD2_k127_7797363_52 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000005678 79.0
HKD2_k127_7797363_53 Response regulator, receiver - - - 0.00000002689 65.0
HKD2_k127_7797363_54 PFAM Haemolysin-type calcium-binding repeat - - - 0.0000003065 62.0
HKD2_k127_7797363_55 Involved in the tonB-independent uptake of proteins - - - 0.0000004612 62.0
HKD2_k127_7797363_56 Protein of unknown function (DUF4079) - - - 0.0001262 54.0
HKD2_k127_7797363_57 pyridoxamine 5-phosphate K07005 - - 0.0002708 49.0
HKD2_k127_7797363_58 Protein of unknown function (DUF2889) - - - 0.0005338 52.0
HKD2_k127_7797363_6 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 547.0
HKD2_k127_7797363_7 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 501.0
HKD2_k127_7797363_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 448.0
HKD2_k127_7797363_9 DinB superfamily K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 448.0
HKD2_k127_7842152_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.443e-307 982.0
HKD2_k127_7842152_1 6-phosphogluconolactonase activity - - - 3.74e-240 796.0
HKD2_k127_7842152_10 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002755 267.0
HKD2_k127_7842152_11 Cytochrome c K00406,K16255 - - 0.00000000000000000000000000000000000000000000000000000007547 208.0
HKD2_k127_7842152_12 cytochrome c oxidase K00405 - - 0.00000000000000000000000000000000000000000000000000005663 195.0
HKD2_k127_7842152_13 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein - - - 0.0000000000000000000000000000000000000000000000003392 192.0
HKD2_k127_7842152_14 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000004238 182.0
HKD2_k127_7842152_15 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000003972 196.0
HKD2_k127_7842152_16 NnrS protein K07234 - - 0.0000000000000000000000000000000000000006528 166.0
HKD2_k127_7842152_17 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000001598 162.0
HKD2_k127_7842152_18 Biogenesis protein K09792 - - 0.0000000000000000000000000000000001213 144.0
HKD2_k127_7842152_19 PFAM Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000002999 130.0
HKD2_k127_7842152_2 COGs COG3278 Cbb3-type cytochrome oxidase subunit 1 K00404,K15862 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 515.0
HKD2_k127_7842152_20 Sulfotransferase domain - - - 0.0000000000000000000000007491 122.0
HKD2_k127_7842152_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000001811 95.0
HKD2_k127_7842152_22 PFAM CBS domain containing protein K07168 - - 0.00000000000000001117 96.0
HKD2_k127_7842152_23 CAAX protease self-immunity - - - 0.00000000007027 76.0
HKD2_k127_7842152_24 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000001161 64.0
HKD2_k127_7842152_25 - - - - 0.00009548 53.0
HKD2_k127_7842152_3 Cation transport ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 386.0
HKD2_k127_7842152_4 Aromatic amino acid lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 372.0
HKD2_k127_7842152_5 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 318.0
HKD2_k127_7842152_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 319.0
HKD2_k127_7842152_7 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 318.0
HKD2_k127_7842152_8 B12 binding domain K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 310.0
HKD2_k127_7842152_9 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000247 297.0
HKD2_k127_7852951_0 L-carnitine dehydratase bile acid-inducible protein F - - - 1.518e-235 771.0
HKD2_k127_7852951_1 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000003169 228.0
HKD2_k127_7852951_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000007008 171.0
HKD2_k127_7852951_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000001829 121.0
HKD2_k127_7852951_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000003901 96.0
HKD2_k127_7852951_5 - - - - 0.0000000000000002821 80.0
HKD2_k127_7852951_6 peptidyl-tyrosine sulfation - - - 0.000000000000001217 91.0
HKD2_k127_7852951_7 Domain of unknown function (DUF4070) - - - 0.000000000000001522 79.0
HKD2_k127_7852951_8 Transcriptional regulator, Crp Fnr family - - - 0.0000000000002048 74.0
HKD2_k127_789543_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 521.0
HKD2_k127_789543_1 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 328.0
HKD2_k127_789543_10 PFAM Glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000002063 179.0
HKD2_k127_789543_11 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000001013 161.0
HKD2_k127_789543_12 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000002807 132.0
HKD2_k127_789543_13 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.0000000000000000000000007193 121.0
HKD2_k127_789543_15 methyltransferase - - - 0.00000000000000002928 90.0
HKD2_k127_789543_16 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains K02688 - - 0.00006681 45.0
HKD2_k127_789543_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 330.0
HKD2_k127_789543_3 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 304.0
HKD2_k127_789543_4 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005225 270.0
HKD2_k127_789543_5 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000006855 261.0
HKD2_k127_789543_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000003561 245.0
HKD2_k127_789543_7 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000004311 197.0
HKD2_k127_789543_8 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.000000000000000000000000000000000000000000000000005025 184.0
HKD2_k127_789543_9 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000532 184.0
HKD2_k127_7900557_0 Pfam Sulfatase - - - 1.386e-223 704.0
HKD2_k127_7900557_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 506.0
HKD2_k127_7900557_10 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000000000002244 160.0
HKD2_k127_7900557_11 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000001193 123.0
HKD2_k127_7900557_12 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000001122 73.0
HKD2_k127_7900557_13 Major Facilitator Superfamily - - - 0.0000000000004955 83.0
HKD2_k127_7900557_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 457.0
HKD2_k127_7900557_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 429.0
HKD2_k127_7900557_4 Methyltransferase small domain K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 330.0
HKD2_k127_7900557_5 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
HKD2_k127_7900557_6 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005583 266.0
HKD2_k127_7900557_7 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006208 248.0
HKD2_k127_7900557_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002822 258.0
HKD2_k127_7900557_9 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000121 212.0
HKD2_k127_7922673_0 HpcH/HpaI aldolase/citrate lyase family K08691 - 4.1.3.24,4.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 573.0
HKD2_k127_7922673_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 6.2.1.5 0.0000000000000000000000000000000000000000000000007536 176.0
HKD2_k127_7922673_2 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000001735 166.0
HKD2_k127_7922673_3 belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000007035 134.0
HKD2_k127_7922673_5 Protein of unknown function, DUF481 - - - 0.000000000000000000414 99.0
HKD2_k127_7943781_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1088.0
HKD2_k127_7943781_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 8.373e-283 888.0
HKD2_k127_7943781_10 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006204 271.0
HKD2_k127_7943781_11 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001027 256.0
HKD2_k127_7943781_12 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008148 273.0
HKD2_k127_7943781_13 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000001908 250.0
HKD2_k127_7943781_14 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000001787 235.0
HKD2_k127_7943781_15 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000004587 194.0
HKD2_k127_7943781_16 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000001233 189.0
HKD2_k127_7943781_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000009089 191.0
HKD2_k127_7943781_18 Domain of unknown function (DUF4215) - - - 0.000000000000000000000000000000000000000000000002971 199.0
HKD2_k127_7943781_19 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000007506 167.0
HKD2_k127_7943781_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 492.0
HKD2_k127_7943781_20 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000001123 147.0
HKD2_k127_7943781_21 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.00000000000000000000000000000000002032 155.0
HKD2_k127_7943781_22 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000009573 136.0
HKD2_k127_7943781_23 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000008056 146.0
HKD2_k127_7943781_24 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000001597 105.0
HKD2_k127_7943781_25 nucleic-acid-binding protein containing a Zn-ribbon - - - 0.000000000000000000009171 97.0
HKD2_k127_7943781_26 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000006393 96.0
HKD2_k127_7943781_27 Patatin-like phospholipase K07001 - - 0.000000000000001622 91.0
HKD2_k127_7943781_28 Bacterial regulatory proteins, tetR family - - - 0.000000000000003614 83.0
HKD2_k127_7943781_29 extracellular structure organization - GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0016043,GO:0030198,GO:0030587,GO:0031012,GO:0031154,GO:0032502,GO:0042221,GO:0043062,GO:0044421,GO:0048856,GO:0050896,GO:0051703,GO:0051704,GO:0071840,GO:0080184,GO:0090702,GO:0099120,GO:1901700,GO:1902168,GO:1905395 - 0.00000000000001028 88.0
HKD2_k127_7943781_3 dioxygenase K11159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 451.0
HKD2_k127_7943781_30 BolA-like protein - - - 0.000000000000614 72.0
HKD2_k127_7943781_31 cell adhesion K02650,K02682 - - 0.000000000006083 78.0
HKD2_k127_7943781_32 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000006356 78.0
HKD2_k127_7943781_33 DUF218 domain - - - 0.00000002054 65.0
HKD2_k127_7943781_34 - - - - 0.000003071 58.0
HKD2_k127_7943781_35 metallopeptidase activity K01126,K01181 - 3.1.4.46,3.2.1.8 0.00008128 55.0
HKD2_k127_7943781_4 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 406.0
HKD2_k127_7943781_5 L-carnitine dehydratase bile acid-inducible protein F K13607,K20882 - 2.8.3.17,2.8.3.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 392.0
HKD2_k127_7943781_6 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 391.0
HKD2_k127_7943781_7 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 349.0
HKD2_k127_7943781_8 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 335.0
HKD2_k127_7943781_9 Phosphotriesterase family K07048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 321.0
HKD2_k127_7947598_0 transferase K01027,K01028,K01031 - 2.8.3.5,2.8.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 367.0
HKD2_k127_7947598_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 329.0
HKD2_k127_7947598_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 303.0
HKD2_k127_7947598_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000002308 66.0
HKD2_k127_8021776_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1248.0
HKD2_k127_8021776_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 1.183e-246 779.0
HKD2_k127_8021776_10 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 257.0
HKD2_k127_8021776_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000001939 236.0
HKD2_k127_8021776_12 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000005326 203.0
HKD2_k127_8021776_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000009597 149.0
HKD2_k127_8021776_14 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000002588 145.0
HKD2_k127_8021776_15 protein with SCP PR1 domains - - - 0.000000000000000000000000000001424 131.0
HKD2_k127_8021776_16 PEP-CTERM motif - - - 0.00000000000000000000000000009654 132.0
HKD2_k127_8021776_17 tRNA modification K06968 - 2.1.1.186 0.00000000000000000000003351 109.0
HKD2_k127_8021776_18 ribosomal large subunit export from nucleus - - - 0.00000000001343 72.0
HKD2_k127_8021776_19 Peptidyl-prolyl cis-trans isomerase - - - 0.0000000002111 68.0
HKD2_k127_8021776_2 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 1.372e-210 675.0
HKD2_k127_8021776_20 outer membrane autotransporter barrel domain - - - 0.00000000788 68.0
HKD2_k127_8021776_22 Tellurite resistance protein TerB K05801 - - 0.00005173 54.0
HKD2_k127_8021776_3 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.538e-203 649.0
HKD2_k127_8021776_4 NLP P60 protein - - - 1.412e-198 641.0
HKD2_k127_8021776_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 598.0
HKD2_k127_8021776_6 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 583.0
HKD2_k127_8021776_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 456.0
HKD2_k127_8021776_8 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 433.0
HKD2_k127_8021776_9 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003313 255.0
HKD2_k127_8089880_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 573.0
HKD2_k127_8089880_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 435.0
HKD2_k127_8089880_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 420.0
HKD2_k127_8089880_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000002253 249.0
HKD2_k127_8089880_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000002572 252.0
HKD2_k127_8089880_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000002502 217.0
HKD2_k127_8089880_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000003094 190.0
HKD2_k127_8089880_7 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000004514 184.0
HKD2_k127_8089880_8 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000008648 120.0
HKD2_k127_8097425_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 578.0
HKD2_k127_8097425_1 AMP-binding enzyme C-terminal domain K04116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 391.0
HKD2_k127_8097425_10 guanyl-nucleotide exchange factor activity K12287 - - 0.00001579 58.0
HKD2_k127_8097425_11 guanyl-nucleotide exchange factor activity K12287 - - 0.00002646 56.0
HKD2_k127_8097425_2 Belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 381.0
HKD2_k127_8097425_3 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000003916 278.0
HKD2_k127_8097425_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000003015 153.0
HKD2_k127_8097425_5 Platelet-activating factor acetylhydrolase, isoform II - - - 0.000000000000000000000000000004319 134.0
HKD2_k127_8097425_6 PFAM Tetratricopeptide repeat - - - 0.000000000000003607 85.0
HKD2_k127_8097425_7 regulatory protein, arsR - - - 0.00000000000324 71.0
HKD2_k127_8097425_8 PhoQ Sensor - - - 0.0000000001675 64.0
HKD2_k127_8097425_9 Pectate lyase - - - 0.0000005664 63.0
HKD2_k127_8216782_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 505.0
HKD2_k127_8216782_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 431.0
HKD2_k127_8216782_10 HNH nucleases - - - 0.0000000000000000000000000000000006599 145.0
HKD2_k127_8216782_11 GntR family - - - 0.000000000000000000003727 102.0
HKD2_k127_8216782_12 Regulatory protein, FmdB family - - - 0.00000000000000001191 85.0
HKD2_k127_8216782_2 extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 439.0
HKD2_k127_8216782_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 323.0
HKD2_k127_8216782_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000747 300.0
HKD2_k127_8216782_5 COG0183 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008355 284.0
HKD2_k127_8216782_6 synthase component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000001512 279.0
HKD2_k127_8216782_7 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000007819 211.0
HKD2_k127_8216782_8 Amino-transferase class IV K00824,K00826 - 2.6.1.21,2.6.1.42 0.0000000000000000000000000000000000000000000000005994 198.0
HKD2_k127_8216782_9 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000002736 194.0
HKD2_k127_8242802_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1170.0
HKD2_k127_8242802_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.724e-319 1021.0
HKD2_k127_8242802_10 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 313.0
HKD2_k127_8242802_11 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002422 258.0
HKD2_k127_8242802_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000002156 216.0
HKD2_k127_8242802_13 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000002207 239.0
HKD2_k127_8242802_14 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000001046 198.0
HKD2_k127_8242802_15 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000009779 177.0
HKD2_k127_8242802_16 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000004858 166.0
HKD2_k127_8242802_17 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000002014 166.0
HKD2_k127_8242802_18 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000004451 137.0
HKD2_k127_8242802_19 transport system involved in gliding motility, auxiliary K01992 - - 0.000000000000000000000000000000008957 147.0
HKD2_k127_8242802_2 Hsp70 protein K04043,K04044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 592.0
HKD2_k127_8242802_20 Transcriptional regulator - - - 0.00000000000000000000000000001582 124.0
HKD2_k127_8242802_21 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000822 136.0
HKD2_k127_8242802_22 iron--sulfur cluster insertion protein erpA K13628,K15724 - - 0.00000000000000000000000000009594 118.0
HKD2_k127_8242802_23 Protein of unknown function (DUF1573) - - - 0.0000000000000000000000008082 120.0
HKD2_k127_8242802_24 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000003532 112.0
HKD2_k127_8242802_25 Pilus assembly protein, PilO K02664 - - 0.000000000000000000003359 108.0
HKD2_k127_8242802_26 DnaJ molecular chaperone homology domain K04082 - - 0.00000000000000000000671 101.0
HKD2_k127_8242802_27 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000001211 106.0
HKD2_k127_8242802_28 Sh3 type 3 domain protein - - - 0.000000000000000001194 101.0
HKD2_k127_8242802_29 negative regulation of protein export from nucleus K10683 GO:0000003,GO:0000151,GO:0000152,GO:0000209,GO:0000726,GO:0000729,GO:0001894,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006508,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007050,GO:0007276,GO:0007283,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010629,GO:0010941,GO:0010942,GO:0016567,GO:0016579,GO:0016604,GO:0016607,GO:0016740,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0019787,GO:0019899,GO:0019900,GO:0019953,GO:0022402,GO:0022414,GO:0031323,GO:0031324,GO:0031436,GO:0031440,GO:0031441,GO:0031974,GO:0031981,GO:0032386,GO:0032387,GO:0032446,GO:0032501,GO:0032504,GO:0032507,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033157,GO:0033365,GO:0033554,GO:0034504,GO:0034613,GO:0034641,GO:0034645,GO:0035770,GO:0036211,GO:0036464,GO:0042176,GO:0042325,GO:0042592,GO:0042802,GO:0042803,GO:0042981,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0045185,GO:0045732,GO:0045786,GO:0045934,GO:0046483,GO:0046822,GO:0046823,GO:0046825,GO:0046826,GO:0046982,GO:0046983,GO:0048232,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0048871,GO:0050684,GO:0050686,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051051,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051235,GO:0051246,GO:0051247,GO:0051252,GO:0051253,GO:0051457,GO:0051641,GO:0051651,GO:0051704,GO:0051716,GO:0051726,GO:0060249,GO:0060255,GO:0060341,GO:0060548,GO:0061630,GO:0061659,GO:0065007,GO:0065008,GO:0070013,GO:0070201,GO:0070531,GO:0070646,GO:0070647,GO:0070727,GO:0071704,GO:0072595,GO:0080090,GO:0085020,GO:0090087,GO:0090304,GO:0090317,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1902494,GO:1903311,GO:1903312,GO:1903827,GO:1903828,GO:1904950,GO:1990234,GO:1990904 - 0.00000000001699 73.0
HKD2_k127_8242802_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 559.0
HKD2_k127_8242802_30 Pilus assembly protein, PilP K02665 - - 0.0000000003198 72.0
HKD2_k127_8242802_31 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00048 51.0
HKD2_k127_8242802_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 516.0
HKD2_k127_8242802_5 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 508.0
HKD2_k127_8242802_6 Exporters of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 451.0
HKD2_k127_8242802_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 336.0
HKD2_k127_8242802_8 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 331.0
HKD2_k127_8242802_9 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 328.0
HKD2_k127_8305571_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 360.0
HKD2_k127_8305571_1 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006907 285.0
HKD2_k127_8322612_0 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 536.0
HKD2_k127_8322612_1 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 419.0
HKD2_k127_8322612_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 299.0
HKD2_k127_8322612_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003893 283.0
HKD2_k127_8322612_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000005453 121.0
HKD2_k127_8327290_0 synthetase K00666,K18688 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 609.0
HKD2_k127_8327290_1 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 381.0
HKD2_k127_8327290_2 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.0000000000000000000000000007921 124.0
HKD2_k127_8327290_3 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000007613 97.0
HKD2_k127_83805_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1414.0
HKD2_k127_83805_1 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 615.0
HKD2_k127_83805_10 Efflux pump membrane transporter - - - 0.00000000000000000000000000000000000000001204 156.0
HKD2_k127_83805_11 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000000000006297 153.0
HKD2_k127_83805_12 Ion transport 2 domain protein - - - 0.000000000000000000000000000000005709 136.0
HKD2_k127_83805_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0000000000000000000000000000004545 134.0
HKD2_k127_83805_14 YMGG-like Gly-zipper - - - 0.00000000000000000005409 97.0
HKD2_k127_83805_2 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 513.0
HKD2_k127_83805_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
HKD2_k127_83805_4 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 464.0
HKD2_k127_83805_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 301.0
HKD2_k127_83805_6 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000231 226.0
HKD2_k127_83805_7 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000002034 196.0
HKD2_k127_83805_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000001527 209.0
HKD2_k127_8394806_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004707 285.0
HKD2_k127_8394806_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000001445 101.0
HKD2_k127_8394806_2 DNA-sulfur modification-associated - - - 0.0000001052 64.0
HKD2_k127_8395811_0 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 428.0
HKD2_k127_8395811_1 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008385 276.0
HKD2_k127_8395811_2 KR domain K08261,K21620 - 1.1.1.16,1.1.99.21 0.000000000000000000000000000000000003834 149.0
HKD2_k127_8395811_3 metallopeptidase activity - - - 0.0000000000000000000000000000004163 134.0
HKD2_k127_8395811_4 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000007083 100.0
HKD2_k127_8463731_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 373.0
HKD2_k127_8463731_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 331.0
HKD2_k127_8463731_2 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 330.0
HKD2_k127_8463731_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
HKD2_k127_8463731_4 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000005994 217.0
HKD2_k127_8463731_5 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000000000000000000000000002013 213.0
HKD2_k127_8463731_6 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000003566 203.0
HKD2_k127_8463731_7 transcriptional regulator - - - 0.000000000000000000000000002339 120.0
HKD2_k127_8463731_8 Tryptophan halogenase - - - 0.0000000000000000002342 101.0
HKD2_k127_852508_0 Pfam:CPSase_L_chain - - - 0.0 1095.0
HKD2_k127_852508_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 525.0
HKD2_k127_852508_2 related to 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 403.0
HKD2_k127_852508_3 in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor' K14260 GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0019842,GO:0030170,GO:0030632,GO:0032787,GO:0033554,GO:0036094,GO:0042221,GO:0042851,GO:0042852,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0046677,GO:0047635,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.2,2.6.1.66 0.00000000000000000000000000000000000000000000003727 175.0
HKD2_k127_852508_4 NUDIX domain - - - 0.000000000000000000000000000000000000001412 156.0
HKD2_k127_852508_5 PFAM SNARE associated Golgi protein - - - 0.000000000001795 80.0
HKD2_k127_852508_6 Putative zinc- or iron-chelating domain K06940 - - 0.000000000001958 72.0
HKD2_k127_852508_7 Pfam Hemerythrin HHE - - - 0.000002504 56.0
HKD2_k127_8540457_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1079.0
HKD2_k127_8540457_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
HKD2_k127_8540457_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000003634 206.0
HKD2_k127_8540457_3 - - - - 0.0000000000000000000000000005094 115.0
HKD2_k127_8540457_4 Glycine-zipper domain - - - 0.000000000000000000000000008727 114.0
HKD2_k127_8540457_5 Ammonium Transporter Family K03320 - - 0.0000000000000000000000001814 108.0
HKD2_k127_8540457_6 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000005585 103.0
HKD2_k127_8573683_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 1.478e-220 701.0
HKD2_k127_8573683_1 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 582.0
HKD2_k127_8573683_10 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001245 256.0
HKD2_k127_8573683_11 Enoyl-(Acyl carrier protein) reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000008977 269.0
HKD2_k127_8573683_12 MazG nucleotide pyrophosphohydrolase domain K02499,K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000005799 251.0
HKD2_k127_8573683_13 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000007651 268.0
HKD2_k127_8573683_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000007669 250.0
HKD2_k127_8573683_15 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000005234 238.0
HKD2_k127_8573683_16 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000001698 224.0
HKD2_k127_8573683_17 ATP cone domain K07738 - - 0.000000000000000000000000000000000000000000000000000000011 202.0
HKD2_k127_8573683_18 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000001585 214.0
HKD2_k127_8573683_19 cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000001767 194.0
HKD2_k127_8573683_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 444.0
HKD2_k127_8573683_20 PFAM cyclase family protein K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000001194 194.0
HKD2_k127_8573683_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000002516 177.0
HKD2_k127_8573683_22 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000001045 188.0
HKD2_k127_8573683_23 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000004983 166.0
HKD2_k127_8573683_24 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000001917 172.0
HKD2_k127_8573683_25 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000005603 151.0
HKD2_k127_8573683_26 protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000001652 153.0
HKD2_k127_8573683_27 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000003929 143.0
HKD2_k127_8573683_28 type III effector K22129 - 2.7.1.219,2.7.1.220 0.0000000000000000000000000000000006198 145.0
HKD2_k127_8573683_29 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000002113 128.0
HKD2_k127_8573683_3 PFAM ATP phosphoribosyltransferase, catalytic region K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 400.0
HKD2_k127_8573683_30 4Fe-4S binding domain - - - 0.0000000000000000000000000000006863 127.0
HKD2_k127_8573683_31 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000002276 112.0
HKD2_k127_8573683_32 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000004252 111.0
HKD2_k127_8573683_33 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000003685 119.0
HKD2_k127_8573683_34 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000007619 114.0
HKD2_k127_8573683_35 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000001976 106.0
HKD2_k127_8573683_36 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000001494 109.0
HKD2_k127_8573683_37 metal-binding protein, possibly nucleic-acid binding protein K07040 - - 0.00000000000000000257 96.0
HKD2_k127_8573683_38 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000531 85.0
HKD2_k127_8573683_39 competence protein - - - 0.000000000000008507 76.0
HKD2_k127_8573683_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 351.0
HKD2_k127_8573683_40 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000002009 77.0
HKD2_k127_8573683_41 Lipopolysaccharide-assembly - - - 0.000000002332 68.0
HKD2_k127_8573683_42 Tetratricopeptide repeat - - - 0.000000005713 68.0
HKD2_k127_8573683_5 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 354.0
HKD2_k127_8573683_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 333.0
HKD2_k127_8573683_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 310.0
HKD2_k127_8573683_8 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000138 301.0
HKD2_k127_8573683_9 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009579 282.0
HKD2_k127_8600792_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.3e-257 818.0
HKD2_k127_8600792_1 nickel-dependent hydrogenase, large subunit K06281 - 1.12.99.6 1.313e-239 777.0
HKD2_k127_8600792_10 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000006177 186.0
HKD2_k127_8600792_11 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000005229 127.0
HKD2_k127_8600792_12 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000001172 108.0
HKD2_k127_8600792_13 HupF/HypC family K04653 - - 0.00000000000000000001014 95.0
HKD2_k127_8600792_14 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000006322 66.0
HKD2_k127_8600792_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 467.0
HKD2_k127_8600792_3 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 463.0
HKD2_k127_8600792_4 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 383.0
HKD2_k127_8600792_5 COG1680 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 387.0
HKD2_k127_8600792_6 PFAM Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 358.0
HKD2_k127_8600792_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 292.0
HKD2_k127_8600792_8 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004364 291.0
HKD2_k127_8600792_9 Repeat of unknown function (DUF346) - - - 0.0000000000000000000000000000000000000000000000007184 199.0
HKD2_k127_8711355_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 505.0
HKD2_k127_8711355_1 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 485.0
HKD2_k127_8711355_10 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000003154 156.0
HKD2_k127_8711355_11 Endoribonuclease L-PSP - - - 0.00000000000000000000000004364 121.0
HKD2_k127_8711355_12 - - - - 0.000000000000000000000002183 117.0
HKD2_k127_8711355_13 CBS domain K04767,K07168,K07182 - - 0.000000000000000000000004507 118.0
HKD2_k127_8711355_15 NnrU protein - - - 0.000000000000000000002496 104.0
HKD2_k127_8711355_16 DNA primase activity - - - 0.0000000000000000601 94.0
HKD2_k127_8711355_17 - - - - 0.0000000000000001493 95.0
HKD2_k127_8711355_18 lipolytic protein G-D-S-L family - - - 0.00000000008905 76.0
HKD2_k127_8711355_2 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 305.0
HKD2_k127_8711355_20 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.000000007628 65.0
HKD2_k127_8711355_21 Glycosyltransferase like family 2 - - - 0.000005576 58.0
HKD2_k127_8711355_22 MHC class II protein binding, via antigen binding groove - - - 0.0001787 53.0
HKD2_k127_8711355_3 Thiamine pyrophosphate enzyme, central domain K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003579 291.0
HKD2_k127_8711355_4 homoserine kinase type II (Protein kinase fold) - - - 0.0000000000000000000000000000000000000000000000000000000000000001315 233.0
HKD2_k127_8711355_5 ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000005158 202.0
HKD2_k127_8711355_6 Diacylglycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000007582 195.0
HKD2_k127_8711355_7 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000001976 198.0
HKD2_k127_8711355_8 Diacylglycerol O-acyltransferase - - - 0.0000000000000000000000000000000000000000000007916 190.0
HKD2_k127_8711355_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000009824 152.0
HKD2_k127_8775125_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
HKD2_k127_8775125_1 Adventurous gliding motility protein R - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004811 291.0
HKD2_k127_8775125_2 PFAM ABC transporter related K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003481 259.0
HKD2_k127_8775125_3 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000013 201.0
HKD2_k127_8775125_4 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000207 171.0
HKD2_k127_8775125_5 Cobalt transport protein K16785,K16786,K16787 - - 0.0000000000000000000000000000002686 140.0
HKD2_k127_8778710_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789 - - 0.0 1440.0
HKD2_k127_8778710_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1310.0
HKD2_k127_8778710_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000004627 129.0
HKD2_k127_8778710_11 6-phosphogluconolactonase activity - - - 0.0000000000000000000002411 113.0
HKD2_k127_8778710_2 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 563.0
HKD2_k127_8778710_3 Outer membrane efflux protein K18903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 480.0
HKD2_k127_8778710_4 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 431.0
HKD2_k127_8778710_5 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 423.0
HKD2_k127_8778710_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 416.0
HKD2_k127_8778710_7 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000178 163.0
HKD2_k127_8778710_8 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000002568 166.0
HKD2_k127_8778710_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000005436 164.0
HKD2_k127_8801681_0 Belongs to the arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001642 268.0
HKD2_k127_8801681_1 MutL protein - - - 0.000000000000000000000000000000000000000000000000000004404 198.0
HKD2_k127_8969333_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 617.0
HKD2_k127_8969333_1 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 472.0
HKD2_k127_8969333_2 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 459.0
HKD2_k127_8969333_3 COG0625 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 383.0
HKD2_k127_8969333_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000821 314.0
HKD2_k127_8969333_5 arylsulfatase activity K07014 - - 0.0000000000000000000000005968 116.0
HKD2_k127_8969333_6 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000002318 85.0
HKD2_k127_8969333_7 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00034 - 1.1.1.47 0.0000000001983 63.0
HKD2_k127_8976439_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 1.675e-223 706.0
HKD2_k127_8976439_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 497.0
HKD2_k127_8976439_2 COG1884 Methylmalonyl-CoA mutase, N-terminal domain subunit K01847,K01848 GO:0003674,GO:0003824,GO:0004494,GO:0005488,GO:0008144,GO:0016853,GO:0016866,GO:0019842,GO:0031419,GO:0036094,GO:0046906,GO:0048037,GO:0097159,GO:1901363 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 341.0
HKD2_k127_8993497_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 583.0
HKD2_k127_8993497_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 562.0
HKD2_k127_8993497_10 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000005458 142.0
HKD2_k127_8993497_11 polysaccharide deacetylase - - - 0.00000000000000000000000000003738 131.0
HKD2_k127_8993497_12 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000007063 115.0
HKD2_k127_8993497_13 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000003943 83.0
HKD2_k127_8993497_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001882 298.0
HKD2_k127_8993497_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 276.0
HKD2_k127_8993497_4 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000009147 224.0
HKD2_k127_8993497_5 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000756 212.0
HKD2_k127_8993497_6 PFAM CobW HypB UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000003245 193.0
HKD2_k127_8993497_7 Radical SAM K22227 - - 0.00000000000000000000000000000000000000000000001207 190.0
HKD2_k127_8993497_8 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000003868 173.0
HKD2_k127_8993497_9 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000007006 177.0
HKD2_k127_9000389_0 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0000724,GO:0000725,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009295,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 359.0
HKD2_k127_9000389_1 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 339.0
HKD2_k127_9000389_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000003225 154.0
HKD2_k127_9000389_3 Peptidase, M23 - - - 0.000000000000000000000000000001992 140.0
HKD2_k127_9000389_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000001443 112.0
HKD2_k127_9000902_0 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 443.0
HKD2_k127_9000902_1 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 338.0
HKD2_k127_9000902_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000634 58.0
HKD2_k127_9000902_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000108 62.0
HKD2_k127_9000902_2 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 304.0
HKD2_k127_9000902_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 300.0
HKD2_k127_9000902_4 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000002557 225.0
HKD2_k127_9000902_5 PAS fold - - - 0.0000000000000000000000000000000000000000000005507 189.0
HKD2_k127_9000902_6 Ring hydroxylating beta subunit - - - 0.000000000000000000000000000000007865 144.0
HKD2_k127_9000902_7 SnoaL-like domain - - - 0.000000000000000000000000000000009445 134.0
HKD2_k127_9000902_8 RNA binding S1 domain protein K06959 - - 0.00000000000000000000000001 126.0
HKD2_k127_9000902_9 hydroperoxide reductase activity - - - 0.0000000000001983 79.0
HKD2_k127_9025236_0 6-phosphogluconolactonase activity - - - 0.0 1047.0
HKD2_k127_9025236_1 Belongs to the heat shock protein 70 family - - - 4.516e-218 736.0
HKD2_k127_9025236_10 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001233 278.0
HKD2_k127_9025236_11 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000001161 206.0
HKD2_k127_9025236_12 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000006117 185.0
HKD2_k127_9025236_13 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000002762 152.0
HKD2_k127_9025236_14 Domain of unknown function (DUF2760) - - - 0.00000000000000000000000000000002396 144.0
HKD2_k127_9025236_15 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000004349 130.0
HKD2_k127_9025236_17 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000005333 116.0
HKD2_k127_9025236_18 Major Facilitator Superfamily - - - 0.000000000000000000001851 108.0
HKD2_k127_9025236_2 Belongs to the heat shock protein 70 family - - - 2.183e-196 638.0
HKD2_k127_9025236_3 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 550.0
HKD2_k127_9025236_4 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 575.0
HKD2_k127_9025236_5 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 481.0
HKD2_k127_9025236_6 Pyruvate kinase K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 463.0
HKD2_k127_9025236_7 of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 394.0
HKD2_k127_9025236_8 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 316.0
HKD2_k127_9025236_9 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001077 284.0
HKD2_k127_9036779_0 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000006413 220.0
HKD2_k127_9036779_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000007119 207.0
HKD2_k127_9036779_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000002645 190.0
HKD2_k127_9036779_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000003046 161.0
HKD2_k127_9103133_0 functions in conversion of succinate to propionate K01847 - 5.4.99.2 3.951e-246 768.0
HKD2_k127_9103133_1 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 299.0
HKD2_k127_9103133_2 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002093 274.0
HKD2_k127_9103133_3 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006651 276.0
HKD2_k127_9103133_4 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000004724 170.0
HKD2_k127_9103133_5 histidine kinase A domain protein K11527 - 2.7.13.3 0.00000000000000000000000000000000000000002081 175.0
HKD2_k127_9103133_6 HDOD domain - - - 0.000000000000000000000000000000002092 147.0
HKD2_k127_9108161_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 1.597e-224 717.0
HKD2_k127_9108161_1 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 526.0
HKD2_k127_9108161_2 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 393.0
HKD2_k127_9108161_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 358.0
HKD2_k127_9108161_4 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002206 282.0
HKD2_k127_9108161_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000009044 245.0
HKD2_k127_9108161_6 Dehydrogenase K00038 - 1.1.1.53 0.00000000000000000000000000000000001026 154.0
HKD2_k127_9108161_7 SnoaL-like domain - - - 0.0000000000000000000000000445 117.0
HKD2_k127_9108161_8 - - - - 0.0000000001544 74.0
HKD2_k127_9108161_9 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083,K01113,K01126 - 3.1.3.1,3.1.3.8,3.1.4.46 0.000224 48.0
HKD2_k127_9108436_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 8.124e-320 1021.0
HKD2_k127_9108436_1 Adenylate and Guanylate cyclase catalytic domain - - - 2.608e-195 657.0
HKD2_k127_9108436_10 CRS1_YhbY K07574 - - 0.0000000000000005013 90.0
HKD2_k127_9108436_11 CARDB - - - 0.00000005643 64.0
HKD2_k127_9108436_12 integral membrane protein - - - 0.00002718 57.0
HKD2_k127_9108436_2 Flavoprotein involved in K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 550.0
HKD2_k127_9108436_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 404.0
HKD2_k127_9108436_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006987 263.0
HKD2_k127_9108436_5 Phosphoesterase family K21302 - 3.1.3.64 0.000000000000000000000000000000000000000000000000000000000000000000004817 244.0
HKD2_k127_9108436_6 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000002111 258.0
HKD2_k127_9108436_7 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000000000000003452 220.0
HKD2_k127_9108436_8 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000609 171.0
HKD2_k127_9108436_9 - - - - 0.000000000000000000005244 102.0
HKD2_k127_9109565_0 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 377.0
HKD2_k127_9109565_1 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 353.0
HKD2_k127_9109565_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000001634 60.0
HKD2_k127_9109565_2 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000139 253.0
HKD2_k127_9109565_3 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000000000000000000000001687 177.0
HKD2_k127_9109565_4 - - - - 0.000000000000000000000000000000000000000000000634 181.0
HKD2_k127_9109565_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000005066 161.0
HKD2_k127_9109565_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000007636 130.0
HKD2_k127_9109565_7 transcriptional regulator - - - 0.0000000000000000000000000001075 123.0
HKD2_k127_9109565_8 Protein conserved in bacteria - - - 0.0000000000000000000000001328 119.0
HKD2_k127_9109565_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000001188 100.0
HKD2_k127_9131548_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 9.973e-228 723.0
HKD2_k127_9131548_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 8.679e-224 719.0
HKD2_k127_9131548_10 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 460.0
HKD2_k127_9131548_11 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 472.0
HKD2_k127_9131548_12 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 453.0
HKD2_k127_9131548_13 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 488.0
HKD2_k127_9131548_14 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 437.0
HKD2_k127_9131548_15 ferredoxin-NADP+ reductase activity K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 419.0
HKD2_k127_9131548_16 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 420.0
HKD2_k127_9131548_17 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 415.0
HKD2_k127_9131548_18 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 439.0
HKD2_k127_9131548_19 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 411.0
HKD2_k127_9131548_2 AcrB/AcrD/AcrF family - - - 1.378e-206 678.0
HKD2_k127_9131548_20 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 420.0
HKD2_k127_9131548_21 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 406.0
HKD2_k127_9131548_22 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 376.0
HKD2_k127_9131548_23 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 366.0
HKD2_k127_9131548_24 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0034645,GO:0036361,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 343.0
HKD2_k127_9131548_25 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008694 344.0
HKD2_k127_9131548_26 synthase K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 338.0
HKD2_k127_9131548_27 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 334.0
HKD2_k127_9131548_28 COG0405 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 329.0
HKD2_k127_9131548_29 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 315.0
HKD2_k127_9131548_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 603.0
HKD2_k127_9131548_30 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 309.0
HKD2_k127_9131548_31 catalyzes the methylation of cytosine at position 1962 of the 23S rRNA K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 300.0
HKD2_k127_9131548_32 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000771 275.0
HKD2_k127_9131548_33 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000005918 278.0
HKD2_k127_9131548_34 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 268.0
HKD2_k127_9131548_35 Belongs to the enoyl-CoA hydratase isomerase family K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000004284 256.0
HKD2_k127_9131548_36 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000002494 250.0
HKD2_k127_9131548_37 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
HKD2_k127_9131548_38 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000001043 262.0
HKD2_k127_9131548_39 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000001846 249.0
HKD2_k127_9131548_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 591.0
HKD2_k127_9131548_40 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000007282 244.0
HKD2_k127_9131548_41 squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000001181 254.0
HKD2_k127_9131548_42 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000001794 250.0
HKD2_k127_9131548_43 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
HKD2_k127_9131548_44 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000003825 245.0
HKD2_k127_9131548_45 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000005376 202.0
HKD2_k127_9131548_46 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000001017 196.0
HKD2_k127_9131548_47 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000009342 184.0
HKD2_k127_9131548_48 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000113 197.0
HKD2_k127_9131548_49 Glucose inhibited division protein A - - - 0.00000000000000000000000000000000000000000000000001909 199.0
HKD2_k127_9131548_5 Zn-dependent metallo-hydrolase RNA specificity domain K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 559.0
HKD2_k127_9131548_50 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000004896 203.0
HKD2_k127_9131548_51 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000001245 199.0
HKD2_k127_9131548_52 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000001282 201.0
HKD2_k127_9131548_53 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000002065 181.0
HKD2_k127_9131548_54 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000006728 170.0
HKD2_k127_9131548_55 homoserine kinase activity K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000001571 179.0
HKD2_k127_9131548_56 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000001533 173.0
HKD2_k127_9131548_57 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000004125 168.0
HKD2_k127_9131548_58 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.000000000000000000000000000000000000000002105 178.0
HKD2_k127_9131548_59 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619 - 1.20.4.1,2.3.1.1 0.0000000000000000000000000000000000000002043 173.0
HKD2_k127_9131548_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 518.0
HKD2_k127_9131548_60 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000001013 161.0
HKD2_k127_9131548_61 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000001623 154.0
HKD2_k127_9131548_62 6-pyruvoyl tetrahydrobiopterin synthase K22101 - 4.1.2.60,4.2.3.12 0.000000000000000000000000000000000000175 159.0
HKD2_k127_9131548_63 COG1145 Ferredoxin - - - 0.000000000000000000000000000000000106 142.0
HKD2_k127_9131548_64 cell septum assembly - - - 0.000000000000000000000000000000006443 148.0
HKD2_k127_9131548_65 PFAM outer membrane efflux protein - - - 0.00000000000000000000000000000006083 143.0
HKD2_k127_9131548_66 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000001377 126.0
HKD2_k127_9131548_67 SMART LamG domain protein jellyroll fold domain protein - - - 0.0000000000000000000000000000959 136.0
HKD2_k127_9131548_69 phosphomevalonate kinase K00938 - 2.7.4.2 0.0000000000000000000000000001817 132.0
HKD2_k127_9131548_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 495.0
HKD2_k127_9131548_70 thiolester hydrolase activity - - - 0.000000000000000000000000008888 119.0
HKD2_k127_9131548_71 Acetyltransferase (GNAT) domain K03824 - - 0.00000000000000000000000001324 126.0
HKD2_k127_9131548_72 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000279 113.0
HKD2_k127_9131548_73 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000004086 118.0
HKD2_k127_9131548_74 Acetoacetate metabolism regulatory protein ATOC - - - 0.0000000000000000000000007996 118.0
HKD2_k127_9131548_75 sterol carrier protein - - - 0.000000000000000000000001108 106.0
HKD2_k127_9131548_76 EamA-like transporter family - - - 0.000000000000000000001398 109.0
HKD2_k127_9131548_77 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000001577 107.0
HKD2_k127_9131548_78 DSBA-like thioredoxin domain - - - 0.00000000000000003564 89.0
HKD2_k127_9131548_79 Acetyltransferase (GNAT) domain - - - 0.00000000000000009685 94.0
HKD2_k127_9131548_8 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 500.0
HKD2_k127_9131548_80 outer membrane efflux protein K15725 - - 0.000000000000004503 88.0
HKD2_k127_9131548_81 ubiE/COQ5 methyltransferase family - - - 0.0000000003949 72.0
HKD2_k127_9131548_82 Sulfurtransferase TusA K04085 - - 0.00000001424 59.0
HKD2_k127_9131548_84 - - - - 0.0000001863 64.0
HKD2_k127_9131548_85 overlaps another CDS with the same product name - - - 0.00005652 55.0
HKD2_k127_9131548_86 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00006409 51.0
HKD2_k127_9131548_87 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0002713 55.0
HKD2_k127_9131548_9 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 466.0
HKD2_k127_9132637_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008125 337.0
HKD2_k127_9132637_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 304.0
HKD2_k127_9132637_2 PFAM Enoyl-CoA hydratase isomerase K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 299.0
HKD2_k127_9132637_4 Domain of Unknown Function (DUF748) - - - 0.000000000000868 83.0
HKD2_k127_9141829_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 600.0
HKD2_k127_9141829_1 peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001719 188.0
HKD2_k127_9141829_2 - - - - 0.00000000000000000000001237 115.0
HKD2_k127_9157459_0 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 327.0
HKD2_k127_9157459_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 333.0
HKD2_k127_9157459_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 329.0
HKD2_k127_9157459_3 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000001993 246.0
HKD2_k127_9157459_4 Domain of unknown function (DUF4394) - - - 0.00000000000000000000000000000000000000000000000000000000000000404 237.0
HKD2_k127_9157459_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
HKD2_k127_9157459_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000003051 167.0
HKD2_k127_9157459_7 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000001268 149.0
HKD2_k127_9157459_8 Anti-sigma-K factor rskA - - - 0.0000000862 64.0
HKD2_k127_9185810_0 molybdopterin cofactor binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 550.0
HKD2_k127_9185810_1 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 490.0
HKD2_k127_9185810_2 Acyl-CoA dehydrogenase, type 2, C-terminal domain K22027 - 1.14.13.235 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 370.0
HKD2_k127_9185810_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 336.0
HKD2_k127_9185810_4 Di-haem oxidoreductase, putative peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 303.0
HKD2_k127_9185810_5 Histidine kinase - - - 0.000000000000000000000000000000000000000246 171.0
HKD2_k127_9185810_6 PFAM Patatin K07001 - - 0.00000000000000000001051 108.0
HKD2_k127_9185810_7 Antibiotic biosynthesis monooxygenase - - - 0.0000000000001908 75.0
HKD2_k127_9215461_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 4.003e-229 743.0
HKD2_k127_9215461_1 nitrous-oxide reductase activity K00376 - 1.7.2.4 2.856e-225 717.0
HKD2_k127_9215461_10 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 358.0
HKD2_k127_9215461_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 359.0
HKD2_k127_9215461_12 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001688 281.0
HKD2_k127_9215461_13 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003824 278.0
HKD2_k127_9215461_14 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001001 288.0
HKD2_k127_9215461_15 alginic acid biosynthetic process K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 299.0
HKD2_k127_9215461_16 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004261 275.0
HKD2_k127_9215461_17 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005158 255.0
HKD2_k127_9215461_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008325 239.0
HKD2_k127_9215461_19 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001065 249.0
HKD2_k127_9215461_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 520.0
HKD2_k127_9215461_20 Transketolase, central region K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000002746 256.0
HKD2_k127_9215461_21 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000003803 199.0
HKD2_k127_9215461_22 Enoyl-(Acyl carrier protein) reductase K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000002281 202.0
HKD2_k127_9215461_23 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000006925 210.0
HKD2_k127_9215461_24 Cytochrome c K00373,K00405,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.000000000000000000000000000000000000000000000000003838 202.0
HKD2_k127_9215461_25 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000002658 188.0
HKD2_k127_9215461_26 - K19341 - - 0.000000000000000000000000000000000000000004436 176.0
HKD2_k127_9215461_27 Domain present in carbohydrate binding proteins and sugar hydrolses K07218 - - 0.0000000000000000000000000000000000000004725 172.0
HKD2_k127_9215461_29 radical SAM domain protein - - - 0.0000000000000000000000000000009803 136.0
HKD2_k127_9215461_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase K02182 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 527.0
HKD2_k127_9215461_30 Glyoxalase-like domain - - - 0.000000000000000000000000005332 119.0
HKD2_k127_9215461_32 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0003919,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008531,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0044237,GO:0070566 2.7.1.26,2.7.7.2 0.0000000000000000000004689 109.0
HKD2_k127_9215461_33 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000002488 97.0
HKD2_k127_9215461_34 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000006326 94.0
HKD2_k127_9215461_35 metalloendopeptidase activity K06261,K08867,K09187,K14972,K20371 - 2.1.1.43,2.7.11.1 0.000000000000005886 88.0
HKD2_k127_9215461_36 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000008877 71.0
HKD2_k127_9215461_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 509.0
HKD2_k127_9215461_5 (ABC) transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 481.0
HKD2_k127_9215461_6 Tryptophan halogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 428.0
HKD2_k127_9215461_7 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 412.0
HKD2_k127_9215461_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 423.0
HKD2_k127_9215461_9 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 383.0
HKD2_k127_9219773_0 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 422.0
HKD2_k127_9219773_1 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000008351 155.0
HKD2_k127_9219773_2 Cas6 Crispr - - - 0.00000000000000000000000000008925 133.0
HKD2_k127_9219773_3 - - - - 0.00000000000000000001515 95.0
HKD2_k127_9256476_0 sulfate adenylyltransferase K00958 - 2.7.7.4 4.289e-200 642.0
HKD2_k127_9256476_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 586.0
HKD2_k127_9256476_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000001456 168.0
HKD2_k127_9256476_3 methionine transport K02071 - - 0.000000000000006144 76.0
HKD2_k127_9256476_4 PFAM UBA THIF-type NAD FAD binding protein K21147 - 2.7.7.80,2.8.1.11 0.00006085 53.0
HKD2_k127_9264812_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 422.0
HKD2_k127_9264812_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 428.0
HKD2_k127_9264812_2 methyltransferase - - - 0.000000000000000000001528 108.0
HKD2_k127_9376550_0 Carbamoyltransferase C-terminus K00612 - - 7.683e-283 881.0
HKD2_k127_9376550_1 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 404.0
HKD2_k127_9376550_2 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000008266 244.0
HKD2_k127_9376550_3 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000001497 219.0
HKD2_k127_9376550_4 - - - - 0.0000000000000000000002097 102.0
HKD2_k127_9376550_5 Sulfotransferase domain - - - 0.0000000000000000000007349 105.0
HKD2_k127_9376550_6 - - - - 0.0000000000000000001225 94.0
HKD2_k127_9376550_7 - - - - 0.000000000000008303 78.0
HKD2_k127_9376550_8 nitroreductase - - - 0.0000002631 64.0
HKD2_k127_9388609_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 472.0
HKD2_k127_9388609_1 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 259.0
HKD2_k127_9388609_2 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000001192 218.0
HKD2_k127_9388609_3 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000001705 192.0
HKD2_k127_9388609_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000001381 184.0
HKD2_k127_9441945_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 5.854e-294 919.0
HKD2_k127_9441945_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K16363 - 3.5.1.108,4.2.1.59 0.00001996 51.0
HKD2_k127_9493767_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.188e-295 928.0
HKD2_k127_9493767_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 577.0
HKD2_k127_9493767_10 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 305.0
HKD2_k127_9493767_11 Belongs to the TtcA family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 303.0
HKD2_k127_9493767_12 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 280.0
HKD2_k127_9493767_13 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003824 256.0
HKD2_k127_9493767_14 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001488 258.0
HKD2_k127_9493767_15 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000004 237.0
HKD2_k127_9493767_16 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000001642 250.0
HKD2_k127_9493767_17 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000167 250.0
HKD2_k127_9493767_18 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000007438 195.0
HKD2_k127_9493767_19 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000003624 170.0
HKD2_k127_9493767_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 555.0
HKD2_k127_9493767_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000005088 160.0
HKD2_k127_9493767_21 Histidine kinase - - - 0.000000000000000000000000000000007683 145.0
HKD2_k127_9493767_22 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000003995 130.0
HKD2_k127_9493767_23 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000002521 126.0
HKD2_k127_9493767_24 Outer membrane protein (OmpH-like) K06142 - - 0.00000000000000000000000306 112.0
HKD2_k127_9493767_25 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000001019 97.0
HKD2_k127_9493767_26 thiamine diphosphate biosynthetic process K03154 - - 0.00000002594 57.0
HKD2_k127_9493767_27 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000001495 63.0
HKD2_k127_9493767_28 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.00003624 56.0
HKD2_k127_9493767_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 506.0
HKD2_k127_9493767_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 458.0
HKD2_k127_9493767_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 364.0
HKD2_k127_9493767_6 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 353.0
HKD2_k127_9493767_7 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 383.0
HKD2_k127_9493767_8 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 326.0
HKD2_k127_9493767_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 326.0
HKD2_k127_9585585_0 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 8.491e-251 798.0
HKD2_k127_9585585_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 5.352e-220 694.0
HKD2_k127_9585585_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000132 295.0
HKD2_k127_9585585_3 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000003196 203.0
HKD2_k127_9585585_4 Hemerythrin HHE cation binding - - - 0.00000008391 59.0
HKD2_k127_9745891_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 1.388e-201 641.0
HKD2_k127_9745891_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 543.0
HKD2_k127_9745891_10 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000003787 188.0
HKD2_k127_9745891_2 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 441.0
HKD2_k127_9745891_3 MFS/sugar transport protein K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 383.0
HKD2_k127_9745891_4 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 382.0
HKD2_k127_9745891_5 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 361.0
HKD2_k127_9745891_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 308.0
HKD2_k127_9745891_7 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 299.0
HKD2_k127_9745891_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000006356 256.0
HKD2_k127_9745891_9 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003504 251.0
HKD2_k127_9794750_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 403.0
HKD2_k127_9794750_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 404.0
HKD2_k127_9794750_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001386 292.0
HKD2_k127_9794750_3 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.000000000000000000000000000000000000000000000000000004006 205.0
HKD2_k127_9794750_4 Asparagine synthase - - - 0.00000000000000000000000000000681 139.0
HKD2_k127_9794750_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000008852 96.0
HKD2_k127_9794750_6 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000002149 85.0
HKD2_k127_9794750_7 Heparinase II/III N-terminus - - - 0.00000000003632 76.0
HKD2_k127_9817787_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 2.866e-304 975.0
HKD2_k127_9817787_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 305.0
HKD2_k127_9817787_3 Diacylglycerol acyltransferase - - - 0.0000000000005755 71.0
HKD2_k127_9817787_4 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.00004718 57.0
HKD2_k127_9969788_0 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 573.0
HKD2_k127_9969788_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 442.0
HKD2_k127_9969788_10 Outer membrane lipoprotein-sorting protein - - - 0.00000000000141 79.0
HKD2_k127_9969788_11 Dodecin - - - 0.00000000011 68.0
HKD2_k127_9969788_12 HPP family - - - 0.000003167 59.0
HKD2_k127_9969788_13 mechanosensitive ion channel - - - 0.0001368 47.0
HKD2_k127_9969788_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 335.0
HKD2_k127_9969788_3 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 310.0
HKD2_k127_9969788_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000675 278.0
HKD2_k127_9969788_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004781 284.0
HKD2_k127_9969788_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
HKD2_k127_9969788_7 alpha-ribazole phosphatase activity K00768,K15634 - 2.4.2.21,5.4.2.12 0.0000000000000000000000000000000000000000000000000001051 192.0
HKD2_k127_9969788_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000005286 209.0
HKD2_k127_9969788_9 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000001303 166.0
HKD2_k127_99856_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 368.0
HKD2_k127_99856_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005527 249.0
HKD2_k127_99856_2 MFS_1 like family - - - 0.000000000000000000000000000000000000002225 154.0
HKD2_k127_99856_3 zinc ion binding K06204 - - 0.000000000000000000000000000000001193 134.0