Overview

ID MAG01802
Name HKD2_bin.5
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum JAUVQV01
Class JAUVQV01
Order JAUVQV01
Family DATDCY01
Genus DATDCY01
Species
Assembly information
Completeness (%) 55.42
Contamination (%) 0.87
GC content (%) 70.0
N50 (bp) 12,326
Genome size (bp) 1,489,586

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1411

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_107797_0 Protein of unknown function (DUF2786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000839 252.0
HKD2_k127_107797_1 Domain of unknown function (DUF362) - - - 0.00000000009533 64.0
HKD2_k127_1234206_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 326.0
HKD2_k127_1234206_1 PAS domain K09155 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 300.0
HKD2_k127_1234206_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000108 209.0
HKD2_k127_1234206_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000000000000000000000000000000000000000009706 200.0
HKD2_k127_1234206_4 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000001513 163.0
HKD2_k127_1234206_5 PFAM Late competence development protein ComFB K02241 - - 0.000002763 57.0
HKD2_k127_1234206_6 PFAM Late competence development protein ComFB K02241 - - 0.000005036 56.0
HKD2_k127_1234206_7 - - - - 0.0003895 51.0
HKD2_k127_1251430_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 553.0
HKD2_k127_1251430_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000001125 177.0
HKD2_k127_1251430_2 TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000002095 174.0
HKD2_k127_1251430_3 Integral membrane protein K07027,K20468 - - 0.00004384 55.0
HKD2_k127_1278960_0 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 9.779e-256 815.0
HKD2_k127_1278960_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.686e-224 714.0
HKD2_k127_1278960_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000001036 138.0
HKD2_k127_1278960_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001262 105.0
HKD2_k127_1278960_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000005942 97.0
HKD2_k127_1278960_13 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000005665 55.0
HKD2_k127_1278960_14 OmpW family K07275 - - 0.00002085 55.0
HKD2_k127_1278960_15 Predicted membrane protein (DUF2232) - - - 0.00003772 55.0
HKD2_k127_1278960_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.958e-207 654.0
HKD2_k127_1278960_3 ABC transporter K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 569.0
HKD2_k127_1278960_4 ABC transporter transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 503.0
HKD2_k127_1278960_5 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 403.0
HKD2_k127_1278960_6 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 328.0
HKD2_k127_1278960_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000001933 183.0
HKD2_k127_1278960_8 - - - - 0.0000000000000000000000000000000000000000000002513 172.0
HKD2_k127_1278960_9 Single-stranded DNA-binding protein K03111 - - 0.0000000000000000000000000000000000004579 145.0
HKD2_k127_1280752_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 608.0
HKD2_k127_1280752_1 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 445.0
HKD2_k127_1280752_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 366.0
HKD2_k127_1280752_3 PFAM Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
HKD2_k127_1280752_4 spore germination K16928 - - 0.000000000000000000000000000000000000000000000000000000001038 211.0
HKD2_k127_1280752_5 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000005008 138.0
HKD2_k127_1281851_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003949 304.0
HKD2_k127_1281851_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003502 291.0
HKD2_k127_1281851_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000007262 265.0
HKD2_k127_1281851_3 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000004838 190.0
HKD2_k127_1281851_4 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000005429 167.0
HKD2_k127_1281851_5 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.000000000000000000000000000000000002629 157.0
HKD2_k127_1281851_6 Tetratricopeptide repeat - - - 0.000000000000000000000004522 111.0
HKD2_k127_1281851_7 Pfam:N_methyl_2 K02650 - - 0.00000000000000000000006984 106.0
HKD2_k127_1281851_8 Type IV pilin PilA K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000006438 82.0
HKD2_k127_1281851_9 COG0457 FOG TPR repeat - - - 0.00000004814 65.0
HKD2_k127_1306222_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.686e-315 974.0
HKD2_k127_1306222_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009697 359.0
HKD2_k127_1306222_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 347.0
HKD2_k127_1306222_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002371 241.0
HKD2_k127_1335970_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000001118 216.0
HKD2_k127_1335970_1 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000003985 153.0
HKD2_k127_1335970_2 diguanylate cyclase - - - 0.0000000000000000000000000004441 133.0
HKD2_k127_1350475_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 336.0
HKD2_k127_1350475_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000001612 197.0
HKD2_k127_1350475_2 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000002282 164.0
HKD2_k127_1350475_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000005303 142.0
HKD2_k127_1358384_0 FAD linked oxidase domain protein - - - 0.0 1421.0
HKD2_k127_1358384_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 2.171e-271 850.0
HKD2_k127_1358384_10 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.0000000000000000000000000000006249 141.0
HKD2_k127_1358384_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000002593 79.0
HKD2_k127_1358384_12 - - - - 0.000003906 58.0
HKD2_k127_1358384_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 331.0
HKD2_k127_1358384_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 289.0
HKD2_k127_1358384_4 Protoglobin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001903 258.0
HKD2_k127_1358384_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000002507 254.0
HKD2_k127_1358384_6 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000001462 171.0
HKD2_k127_1358384_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.000000000000000000000000000000000000000000004311 170.0
HKD2_k127_1358384_8 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000000000005668 183.0
HKD2_k127_1358384_9 Predicted periplasmic protein (DUF2092) - - - 0.00000000000000000000000000000000000000002586 163.0
HKD2_k127_1358787_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1086.0
HKD2_k127_1358787_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 557.0
HKD2_k127_1358787_10 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000507 254.0
HKD2_k127_1358787_11 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000001645 260.0
HKD2_k127_1358787_12 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000002705 190.0
HKD2_k127_1358787_13 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000006018 195.0
HKD2_k127_1358787_14 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000003233 175.0
HKD2_k127_1358787_15 1,7-bisphosphate phosphatase - - - 0.0000000000000000000000000000000000000000008956 166.0
HKD2_k127_1358787_16 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000007554 168.0
HKD2_k127_1358787_17 PFAM Membrane protein of K08972 - - 0.0000000000000000000000000000591 124.0
HKD2_k127_1358787_18 Lipopolysaccharide-assembly - - - 0.0000000000002074 80.0
HKD2_k127_1358787_19 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000003522 74.0
HKD2_k127_1358787_2 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 422.0
HKD2_k127_1358787_20 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000003962 61.0
HKD2_k127_1358787_21 spermidine synthase activity - - - 0.000429 53.0
HKD2_k127_1358787_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 412.0
HKD2_k127_1358787_4 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 399.0
HKD2_k127_1358787_5 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 348.0
HKD2_k127_1358787_6 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 324.0
HKD2_k127_1358787_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 299.0
HKD2_k127_1358787_8 Adenylate kinase, active site lid K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 289.0
HKD2_k127_1358787_9 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003201 272.0
HKD2_k127_1366724_0 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 394.0
HKD2_k127_1366724_1 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 317.0
HKD2_k127_1366724_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004481 258.0
HKD2_k127_1366724_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000004781 143.0
HKD2_k127_1366724_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000001945 127.0
HKD2_k127_1366724_5 PFAM response regulator receiver K02481,K07712 - - 0.0004528 48.0
HKD2_k127_1412371_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 414.0
HKD2_k127_1412371_1 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000000000000000000000000004481 217.0
HKD2_k127_1412371_2 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000001115 189.0
HKD2_k127_1412371_3 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000333 146.0
HKD2_k127_1412371_4 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0006973 45.0
HKD2_k127_1415309_0 GTP-binding protein TypA K06207 - - 7.197e-253 797.0
HKD2_k127_1415309_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000093 558.0
HKD2_k127_1415309_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 405.0
HKD2_k127_1415309_3 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002455 263.0
HKD2_k127_1415309_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000002498 257.0
HKD2_k127_1415309_5 Transglutaminase-like superfamily - - - 0.00001395 55.0
HKD2_k127_14301_0 PFAM peptidase M29, aminopeptidase II K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 430.0
HKD2_k127_14301_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 359.0
HKD2_k127_14301_2 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 344.0
HKD2_k127_14301_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 287.0
HKD2_k127_14301_4 - - - - 0.000000009729 57.0
HKD2_k127_1450762_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 452.0
HKD2_k127_1450762_1 aromatic amino acid beta-eliminating lyase threonine aldolase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 413.0
HKD2_k127_1450762_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 301.0
HKD2_k127_1450762_3 PFAM Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000000000001603 239.0
HKD2_k127_1450762_4 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001466 207.0
HKD2_k127_1450762_5 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000006719 144.0
HKD2_k127_1450762_6 NIL - - - 0.0000000000000000000000000000722 117.0
HKD2_k127_1450762_7 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000001975 128.0
HKD2_k127_1450762_8 NADPH-dependent FMN reductase - - - 0.00000000000000000002591 102.0
HKD2_k127_1450762_9 Ethylbenzene dehydrogenase - - - 0.00000000000003812 86.0
HKD2_k127_1466433_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 610.0
HKD2_k127_1466433_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 517.0
HKD2_k127_1466433_2 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 363.0
HKD2_k127_1466433_3 PFAM HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 336.0
HKD2_k127_1466433_4 COG1108 ABC-type Mn2 Zn2 transport systems permease components K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 310.0
HKD2_k127_1466433_5 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 GO:0000041,GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008144,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 291.0
HKD2_k127_1466433_6 PFAM Smr protein MutS2 - - - 0.0000000000000000000000000009526 118.0
HKD2_k127_1466433_7 Transcriptional regulator - - - 0.00000000000000000000001997 111.0
HKD2_k127_1466433_8 ubiE/COQ5 methyltransferase family - - - 0.000000000078 75.0
HKD2_k127_1466433_9 - - - - 0.0003356 53.0
HKD2_k127_1543119_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 1.537e-228 716.0
HKD2_k127_1543119_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 491.0
HKD2_k127_1543119_10 Cytochrome c554 and c-prime - - - 0.00000000000273 81.0
HKD2_k127_1543119_11 - - - - 0.0000000005064 64.0
HKD2_k127_1543119_12 CarboxypepD_reg-like domain - - - 0.0000000008819 73.0
HKD2_k127_1543119_13 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000349 71.0
HKD2_k127_1543119_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 333.0
HKD2_k127_1543119_3 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 320.0
HKD2_k127_1543119_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 297.0
HKD2_k127_1543119_5 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001334 296.0
HKD2_k127_1543119_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000007812 265.0
HKD2_k127_1543119_7 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000035 195.0
HKD2_k127_1543119_8 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000005631 138.0
HKD2_k127_1543119_9 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000005764 95.0
HKD2_k127_1666819_0 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 497.0
HKD2_k127_1666819_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 438.0
HKD2_k127_1666819_10 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000004319 138.0
HKD2_k127_1666819_11 Pfam:Methyltransf_26 K15460 - 2.1.1.223 0.0000000000000000000000000000000000133 151.0
HKD2_k127_1666819_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000003004 115.0
HKD2_k127_1666819_13 PhoQ Sensor - - - 0.00000000000000000000000001073 120.0
HKD2_k127_1666819_14 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000007793 105.0
HKD2_k127_1666819_15 - - - - 0.0000000000000001663 92.0
HKD2_k127_1666819_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000008213 82.0
HKD2_k127_1666819_17 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000007372 71.0
HKD2_k127_1666819_19 RDD family - - - 0.0000005181 61.0
HKD2_k127_1666819_2 cysteine desulfurase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 394.0
HKD2_k127_1666819_20 - - - - 0.0000355 51.0
HKD2_k127_1666819_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 386.0
HKD2_k127_1666819_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 327.0
HKD2_k127_1666819_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 307.0
HKD2_k127_1666819_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000794 243.0
HKD2_k127_1666819_7 Bacterial transferase hexapeptide (six repeats) K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000006256 233.0
HKD2_k127_1666819_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000001001 188.0
HKD2_k127_1666819_9 protein conserved in bacteria K09798 - - 0.0000000000000000000000000000000000000000000001002 183.0
HKD2_k127_1704191_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 6.049e-203 644.0
HKD2_k127_1704191_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.518e-199 633.0
HKD2_k127_1704191_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 1.219e-197 631.0
HKD2_k127_1704191_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 576.0
HKD2_k127_1704191_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000002745 203.0
HKD2_k127_1704191_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000001004 219.0
HKD2_k127_1704191_6 diguanylate cyclase - - - 0.00000000000000000008866 105.0
HKD2_k127_1740916_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 561.0
HKD2_k127_1740916_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 481.0
HKD2_k127_1740916_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 400.0
HKD2_k127_1740916_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 347.0
HKD2_k127_1740916_4 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001285 288.0
HKD2_k127_1740916_5 - - - - 0.0000001625 56.0
HKD2_k127_1740916_6 Sporulation related domain - - - 0.00004989 57.0
HKD2_k127_1740916_7 - - - - 0.00006187 52.0
HKD2_k127_1830661_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.546e-200 639.0
HKD2_k127_1830661_1 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 530.0
HKD2_k127_1830661_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000003545 127.0
HKD2_k127_1830661_11 Protein of unknown function (DUF2283) - - - 0.0000000000004753 78.0
HKD2_k127_1830661_2 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 436.0
HKD2_k127_1830661_3 virion core protein (lumpy skin disease virus) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 429.0
HKD2_k127_1830661_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000706 278.0
HKD2_k127_1830661_5 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000001493 214.0
HKD2_k127_1830661_6 PFAM DNA methylase N-4 N-6 K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000003476 185.0
HKD2_k127_1830661_7 PFAM PHP domain - - - 0.00000000000000000000000000000000000000103 156.0
HKD2_k127_1830661_8 HIT domain K02503 - - 0.000000000000000000000000000000000001563 142.0
HKD2_k127_1830661_9 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000002686 135.0
HKD2_k127_1836922_0 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 470.0
HKD2_k127_1836922_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 425.0
HKD2_k127_1836922_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000009375 154.0
HKD2_k127_1836922_3 retrograde transport, endosome to Golgi K07095 - - 0.00000000000000000000000000000000009921 138.0
HKD2_k127_1836922_4 Peptidyl-prolyl cis-trans isomerase K01802,K03774 - 5.2.1.8 0.0000000000000000000000000004343 119.0
HKD2_k127_1836922_5 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000189 87.0
HKD2_k127_1836922_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000003291 87.0
HKD2_k127_1974140_0 penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 350.0
HKD2_k127_1974140_1 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 312.0
HKD2_k127_1974140_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000005472 205.0
HKD2_k127_1986374_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 377.0
HKD2_k127_1986374_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 370.0
HKD2_k127_1986374_2 galactose-1-phosphate K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 323.0
HKD2_k127_1986374_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000007291 179.0
HKD2_k127_1986374_4 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000007933 178.0
HKD2_k127_2224590_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.918e-237 743.0
HKD2_k127_2224590_1 PFAM aminotransferase class I and II K10907 - - 1.091e-195 617.0
HKD2_k127_2224590_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 376.0
HKD2_k127_2224590_3 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 347.0
HKD2_k127_2224590_4 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 319.0
HKD2_k127_2224590_5 methyltransferase - - - 0.000000000000000000000000000000000000001184 158.0
HKD2_k127_2224590_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000910,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0032153,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000007386 108.0
HKD2_k127_2462654_0 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000007296 139.0
HKD2_k127_2462654_1 C4-type zinc ribbon domain K07164 - - 0.00000000000000001122 92.0
HKD2_k127_2462654_3 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000002158 58.0
HKD2_k127_2462654_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000001576 51.0
HKD2_k127_254369_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.141e-265 840.0
HKD2_k127_254369_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000001406 207.0
HKD2_k127_254369_2 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000002962 194.0
HKD2_k127_254369_3 Protein of unknown function (DUF1573) - - - 0.00000000000000000000000000000001849 132.0
HKD2_k127_254369_4 - - - - 0.00000000000000001622 93.0
HKD2_k127_2620869_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 332.0
HKD2_k127_2620869_1 Putative glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 308.0
HKD2_k127_2620869_2 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000001745 234.0
HKD2_k127_2620869_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000006374 104.0
HKD2_k127_2620869_4 TIGRFAM cytochrome C family protein - - - 0.000000000000000000009551 104.0
HKD2_k127_2620869_5 Histidine kinase - - - 0.00000000000000009208 88.0
HKD2_k127_2653343_0 protein conserved in bacteria K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 428.0
HKD2_k127_2653343_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 307.0
HKD2_k127_2653343_2 guanylate kinase activity K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000001067 182.0
HKD2_k127_2653343_3 Iron-storage protein K02217 - 1.16.3.2 0.0000000000000000000000001987 108.0
HKD2_k127_2663951_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 2.84e-213 689.0
HKD2_k127_2663951_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 502.0
HKD2_k127_2663951_2 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 482.0
HKD2_k127_2663951_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 360.0
HKD2_k127_2663951_4 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000002946 109.0
HKD2_k127_2663951_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000003058 101.0
HKD2_k127_2679950_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000005023 207.0
HKD2_k127_2679950_2 Right handed beta helix region - - - 0.0000000000001392 78.0
HKD2_k127_2679950_3 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - - - 0.00000006389 65.0
HKD2_k127_2679950_4 cell redox homeostasis - - - 0.0000002572 63.0
HKD2_k127_2695545_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 481.0
HKD2_k127_2695545_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 392.0
HKD2_k127_2695545_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002088 285.0
HKD2_k127_2695545_3 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004751 270.0
HKD2_k127_2695545_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000023 115.0
HKD2_k127_2716041_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 4.753e-213 683.0
HKD2_k127_2716041_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 7.904e-201 663.0
HKD2_k127_2716041_10 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000007114 220.0
HKD2_k127_2716041_11 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002176 186.0
HKD2_k127_2716041_12 PFAM Cold-shock K03704 - - 0.000000000000000000000000002961 111.0
HKD2_k127_2716041_13 - - - - 0.000000000000000000000000004665 124.0
HKD2_k127_2716041_14 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000003512 114.0
HKD2_k127_2716041_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000008176 120.0
HKD2_k127_2716041_16 - - - - 0.00000000000000000000896 94.0
HKD2_k127_2716041_17 Cytosol aminopeptidase family, N-terminal domain - - - 0.0000000002243 74.0
HKD2_k127_2716041_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 507.0
HKD2_k127_2716041_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 467.0
HKD2_k127_2716041_4 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 462.0
HKD2_k127_2716041_5 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 377.0
HKD2_k127_2716041_6 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 341.0
HKD2_k127_2716041_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 331.0
HKD2_k127_2716041_8 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000002452 244.0
HKD2_k127_2716041_9 Enoyl-CoA hydratase/isomerase K01692,K08299 - 4.2.1.149,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000004723 237.0
HKD2_k127_2770937_0 FAD binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.794e-264 826.0
HKD2_k127_2770937_1 isocitrate dehydrogenase activity K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 555.0
HKD2_k127_2770937_10 mRNA binding K07339 - - 0.00000000000004208 86.0
HKD2_k127_2770937_11 Cytochrome c K17222 - - 0.0000000924 61.0
HKD2_k127_2770937_2 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 390.0
HKD2_k127_2770937_3 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 363.0
HKD2_k127_2770937_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 357.0
HKD2_k127_2770937_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002893 237.0
HKD2_k127_2770937_6 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000003604 220.0
HKD2_k127_2770937_7 - - - - 0.00000000000000000000000000000000000000000000004592 179.0
HKD2_k127_2770937_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000001097 164.0
HKD2_k127_2770937_9 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001602 95.0
HKD2_k127_2801426_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 426.0
HKD2_k127_2801426_1 PFAM PhoH-like protein K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 370.0
HKD2_k127_2801426_2 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 339.0
HKD2_k127_2801426_3 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000122 271.0
HKD2_k127_2801426_4 - - - - 0.0000001726 62.0
HKD2_k127_2803076_0 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 489.0
HKD2_k127_2803076_1 Male sterility protein - - - 0.0000000000000000000000000000000000000000000001374 184.0
HKD2_k127_2803076_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000002425 142.0
HKD2_k127_2803076_3 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000005255 136.0
HKD2_k127_2822119_0 Asparagine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 608.0
HKD2_k127_2822119_1 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 487.0
HKD2_k127_2822119_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.000000000000000000000000000000000000000000000006847 186.0
HKD2_k127_2822119_11 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000003946 173.0
HKD2_k127_2822119_12 NUDIX domain - - - 0.0000000000000000000000000000000007443 141.0
HKD2_k127_2822119_13 PFAM Methyltransferase type 11 - - - 0.0000000000000003051 88.0
HKD2_k127_2822119_14 Polysaccharide biosynthesis C-terminal domain K03328 - - 0.000000001665 70.0
HKD2_k127_2822119_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 438.0
HKD2_k127_2822119_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 428.0
HKD2_k127_2822119_4 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 312.0
HKD2_k127_2822119_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 303.0
HKD2_k127_2822119_6 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 290.0
HKD2_k127_2822119_7 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007217 236.0
HKD2_k127_2822119_8 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000945 241.0
HKD2_k127_2822119_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000005288 201.0
HKD2_k127_2906257_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 327.0
HKD2_k127_2906257_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001011 293.0
HKD2_k127_2906257_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000002659 262.0
HKD2_k127_2906257_3 PFAM FMN-binding domain - - - 0.0000000000000000000000000000000000000001377 170.0
HKD2_k127_2949212_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 580.0
HKD2_k127_2949212_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 422.0
HKD2_k127_2949212_2 Domain of unknown function (DUF3524) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001087 288.0
HKD2_k127_2949212_3 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002219 266.0
HKD2_k127_2949212_4 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003352 247.0
HKD2_k127_2949212_5 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000000000000000006756 244.0
HKD2_k127_2949212_6 Phosphodiester glycosidase - - - 0.000000000000000000000000000000000000000000001272 175.0
HKD2_k127_2949212_7 MgtC family K07507 - - 0.000000000000000000000000000000000000000001295 165.0
HKD2_k127_2949212_8 Universal stress protein family - - - 0.0000000000000000000000027 109.0
HKD2_k127_3040540_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 489.0
HKD2_k127_3040540_1 SMART CBS domain containing protein K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 471.0
HKD2_k127_3040540_10 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000002552 93.0
HKD2_k127_3040540_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 422.0
HKD2_k127_3040540_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 319.0
HKD2_k127_3040540_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 325.0
HKD2_k127_3040540_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 308.0
HKD2_k127_3040540_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 294.0
HKD2_k127_3040540_7 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 273.0
HKD2_k127_3040540_8 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000001143 144.0
HKD2_k127_3040540_9 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.00000000000000000000000000000000000371 144.0
HKD2_k127_3044630_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 340.0
HKD2_k127_3044630_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 315.0
HKD2_k127_3044630_2 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 312.0
HKD2_k127_3044630_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000005522 206.0
HKD2_k127_3044630_4 glycyl-radical enzyme activating activity - - - 0.00000000000000000000000000000000000000000000000000000002338 201.0
HKD2_k127_3044630_5 Ami_2 K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000005696 183.0
HKD2_k127_3044630_6 PFAM phosphatidate cytidylyltransferase - - - 0.000000001053 69.0
HKD2_k127_3079009_0 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 2.698e-224 722.0
HKD2_k127_3079009_1 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 587.0
HKD2_k127_3079009_10 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000001196 193.0
HKD2_k127_3079009_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000131 185.0
HKD2_k127_3079009_12 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000978 149.0
HKD2_k127_3079009_13 peroxiredoxin activity - - - 0.0000000000000000000000000000001688 139.0
HKD2_k127_3079009_14 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000003639 126.0
HKD2_k127_3079009_15 RNA-binding S4 domain protein - - - 0.00000000000000000001286 94.0
HKD2_k127_3079009_16 Cytochrome c554 and c-prime - - - 0.00000000000000009622 89.0
HKD2_k127_3079009_17 Yip1 domain - - - 0.0000000000000001288 90.0
HKD2_k127_3079009_18 Protein of unknown function (DUF507) K09804 - - 0.000000000000002735 78.0
HKD2_k127_3079009_19 Domain of unknown function (DUF4115) - - - 0.0000000000001169 83.0
HKD2_k127_3079009_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 481.0
HKD2_k127_3079009_20 Protein of unknown function (DUF507) K09804 - - 0.000000725 55.0
HKD2_k127_3079009_21 - - - - 0.00001043 49.0
HKD2_k127_3079009_23 tetratricopeptide repeat - - - 0.00005925 55.0
HKD2_k127_3079009_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 356.0
HKD2_k127_3079009_4 PFAM Flavin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
HKD2_k127_3079009_5 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001129 292.0
HKD2_k127_3079009_6 recombinase XerD K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008218 273.0
HKD2_k127_3079009_7 PFAM Sulphate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002122 257.0
HKD2_k127_3079009_8 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000002783 210.0
HKD2_k127_3079009_9 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity K00991,K12506 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000001177 187.0
HKD2_k127_3097458_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 8.322e-257 818.0
HKD2_k127_3097458_1 Domain of unknown function (DUF3520) K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 598.0
HKD2_k127_3097458_10 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000007287 228.0
HKD2_k127_3097458_11 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000001981 205.0
HKD2_k127_3097458_12 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000000000000000001851 191.0
HKD2_k127_3097458_13 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000009481 190.0
HKD2_k127_3097458_14 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000002227 171.0
HKD2_k127_3097458_15 Histidine kinase - - - 0.000000000000000000000000000000000000001123 169.0
HKD2_k127_3097458_16 MarR family transcriptional regulator - - - 0.000000000000000000000000000000000000003253 149.0
HKD2_k127_3097458_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000003545 153.0
HKD2_k127_3097458_18 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000004174 154.0
HKD2_k127_3097458_19 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000007189 151.0
HKD2_k127_3097458_2 Bacterial virulence protein (VirJ) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 519.0
HKD2_k127_3097458_20 part of a sulfur-relay system - - - 0.0000000000000000000001159 107.0
HKD2_k127_3097458_21 protein histidine kinase activity - - - 0.00000000000000001131 98.0
HKD2_k127_3097458_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000001567 84.0
HKD2_k127_3097458_23 Rhodanese Homology Domain - - - 0.000000000000002098 87.0
HKD2_k127_3097458_24 Dimerisation domain - - - 0.000000000206 72.0
HKD2_k127_3097458_26 von Willebrand factor (vWF) type A domain K02448 - - 0.000000005384 58.0
HKD2_k127_3097458_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 498.0
HKD2_k127_3097458_4 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 439.0
HKD2_k127_3097458_5 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 394.0
HKD2_k127_3097458_6 PFAM Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 316.0
HKD2_k127_3097458_7 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001071 257.0
HKD2_k127_3097458_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000002264 248.0
HKD2_k127_3097458_9 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000000000000000412 220.0
HKD2_k127_31299_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 490.0
HKD2_k127_31299_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 440.0
HKD2_k127_31299_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000001193 248.0
HKD2_k127_31299_11 Curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000001672 238.0
HKD2_k127_31299_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00033,K00616,K01810,K08300,K13810 - 1.1.1.343,1.1.1.44,2.2.1.2,3.1.26.12,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000001497 228.0
HKD2_k127_31299_13 HD domain - - - 0.0000000000000000000000000000000000000000000000000002399 202.0
HKD2_k127_31299_14 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000003028 185.0
HKD2_k127_31299_15 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000001852 179.0
HKD2_k127_31299_16 - K02450 - - 0.00000000000000000000000000000000001599 146.0
HKD2_k127_31299_17 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000002778 138.0
HKD2_k127_31299_18 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000005999 134.0
HKD2_k127_31299_19 cellulase activity - - - 0.00000000000000000005234 104.0
HKD2_k127_31299_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 390.0
HKD2_k127_31299_20 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000001395 94.0
HKD2_k127_31299_21 Bacterial protein of unknown function (DUF948) - - - 0.000000001512 64.0
HKD2_k127_31299_22 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00003223 51.0
HKD2_k127_31299_23 peptidase S1 and S6, chymotrypsin Hap - - - 0.0003012 51.0
HKD2_k127_31299_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 392.0
HKD2_k127_31299_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 392.0
HKD2_k127_31299_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 375.0
HKD2_k127_31299_6 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 359.0
HKD2_k127_31299_7 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002954 262.0
HKD2_k127_31299_8 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
HKD2_k127_31299_9 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007298 250.0
HKD2_k127_3143505_0 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 418.0
HKD2_k127_3143505_1 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 367.0
HKD2_k127_3143505_2 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000001331 184.0
HKD2_k127_3143505_3 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001415 180.0
HKD2_k127_3143505_4 PAP2 superfamily C-terminal - - - 0.000000000000000000000000000000000000000001507 178.0
HKD2_k127_3143505_5 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.00000000001487 64.0
HKD2_k127_3166117_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006388 277.0
HKD2_k127_3166117_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000008128 241.0
HKD2_k127_3166117_3 Sigma-54 interaction domain K19641 - - 0.0000000000000000000000000000000000000000006887 174.0
HKD2_k127_3166117_4 tRNA synthetases class II (D, K and N) K04568 - - 0.000005992 53.0
HKD2_k127_3214816_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 357.0
HKD2_k127_3214816_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 346.0
HKD2_k127_3214816_2 response regulator K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 303.0
HKD2_k127_3214816_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000001176 98.0
HKD2_k127_3240840_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1223.0
HKD2_k127_3240840_1 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 395.0
HKD2_k127_3240840_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 393.0
HKD2_k127_3240840_3 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 358.0
HKD2_k127_3240840_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000008539 208.0
HKD2_k127_3240840_5 PFAM nitrogen-fixing NifU domain protein K04488 - - 0.00000000000000000000000000000000000000000000000000000005506 202.0
HKD2_k127_3240840_6 Ferredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.000000000000000003097 90.0
HKD2_k127_3240840_7 Regulatory protein, FmdB family - - - 0.00004456 48.0
HKD2_k127_3381868_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 316.0
HKD2_k127_3381868_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001223 272.0
HKD2_k127_3381868_2 PFAM Radical SAM domain protein - - - 0.00000000000000000000007317 112.0
HKD2_k127_3381868_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000009461 80.0
HKD2_k127_3381868_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000001653 81.0
HKD2_k127_3537803_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 375.0
HKD2_k127_3537803_1 L-glutamate biosynthetic process K00265,K00284 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016020,GO:0016053,GO:0016491,GO:0016638,GO:0019676,GO:0019740,GO:0019752,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14,1.4.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 310.0
HKD2_k127_3537803_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000003239 233.0
HKD2_k127_3692805_0 UPF0210 protein K09157 - - 3.715e-209 659.0
HKD2_k127_3692805_1 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 422.0
HKD2_k127_3692805_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 425.0
HKD2_k127_3692805_3 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 318.0
HKD2_k127_3692805_4 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
HKD2_k127_3692805_5 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008072 241.0
HKD2_k127_3692805_6 PFAM amino acid-binding ACT domain protein K03567 - - 0.00000000000000000000000000000000000000000000000002558 194.0
HKD2_k127_3692805_7 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000003201 136.0
HKD2_k127_3692805_8 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000001339 130.0
HKD2_k127_3692805_9 Peptidase family M23 - - - 0.000000000000000000000000000009443 126.0
HKD2_k127_3855427_0 FtsX-like permease family K02004 - - 3.088e-244 780.0
HKD2_k127_3855427_1 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 562.0
HKD2_k127_3855427_10 4Fe-4S binding domain - - - 0.000000000001678 72.0
HKD2_k127_3855427_2 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 428.0
HKD2_k127_3855427_3 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 314.0
HKD2_k127_3855427_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007517 253.0
HKD2_k127_3855427_5 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000001884 234.0
HKD2_k127_3855427_6 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000002102 210.0
HKD2_k127_3855427_7 - - - - 0.0000000000000000000000000000000000000000000000000000008336 208.0
HKD2_k127_3855427_8 RNA-DNA hybrid ribonuclease activity K03470,K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000005964 214.0
HKD2_k127_3855427_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000000000000000000000000000000000000000000003828 173.0
HKD2_k127_3876371_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.419e-291 935.0
HKD2_k127_3876371_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 604.0
HKD2_k127_3876371_10 - - - - 0.000000000004624 77.0
HKD2_k127_3876371_2 flavodoxin nitric oxide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 451.0
HKD2_k127_3876371_3 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 344.0
HKD2_k127_3876371_4 nickel-responsive regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000007854 175.0
HKD2_k127_3876371_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K03585 - - 0.0000000000000000000000000000000000001403 159.0
HKD2_k127_3876371_6 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.0000000000000000000000000000000000003657 148.0
HKD2_k127_3876371_7 - - - - 0.0000000000000000000000000004056 117.0
HKD2_k127_3876371_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000002405 91.0
HKD2_k127_3876371_9 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.0000000000000003198 92.0
HKD2_k127_390880_0 response regulator K02481 - - 3.046e-203 644.0
HKD2_k127_390880_1 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 502.0
HKD2_k127_390880_10 response regulator - - - 0.000000000000000000000000000000000000000009527 161.0
HKD2_k127_390880_11 Pfam Response regulator receiver - - - 0.000000000000000000000000000000000000001905 160.0
HKD2_k127_390880_12 response regulator - - - 0.000000000000000000000000000000000000006161 153.0
HKD2_k127_390880_13 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000003262 139.0
HKD2_k127_390880_14 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000004711 117.0
HKD2_k127_390880_15 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000008798 109.0
HKD2_k127_390880_16 Domain of unknown function (DUF4175) - - - 0.0000000000000000000000001706 124.0
HKD2_k127_390880_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 396.0
HKD2_k127_390880_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 353.0
HKD2_k127_390880_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 294.0
HKD2_k127_390880_5 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003217 271.0
HKD2_k127_390880_6 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000005524 227.0
HKD2_k127_390880_7 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000002339 234.0
HKD2_k127_390880_8 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000001064 229.0
HKD2_k127_390880_9 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000001181 199.0
HKD2_k127_4012821_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0 1366.0
HKD2_k127_4012821_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1075.0
HKD2_k127_4012821_10 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000008174 134.0
HKD2_k127_4012821_11 PFAM Rhodanese domain protein - - - 0.000000000000000000000001214 111.0
HKD2_k127_4012821_12 Transcription factor zinc-finger K09981 - - 0.00000000000000000000002271 112.0
HKD2_k127_4012821_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 564.0
HKD2_k127_4012821_3 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 470.0
HKD2_k127_4012821_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 429.0
HKD2_k127_4012821_5 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001571 279.0
HKD2_k127_4012821_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000149 280.0
HKD2_k127_4012821_7 PFAM peptidase M48 Ste24p K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001859 276.0
HKD2_k127_4012821_8 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000001087 186.0
HKD2_k127_4012821_9 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000005939 171.0
HKD2_k127_4062990_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.827e-270 846.0
HKD2_k127_4062990_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.308e-219 706.0
HKD2_k127_4062990_10 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 318.0
HKD2_k127_4062990_11 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 309.0
HKD2_k127_4062990_12 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 301.0
HKD2_k127_4062990_13 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003304 279.0
HKD2_k127_4062990_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005383 268.0
HKD2_k127_4062990_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000001148 235.0
HKD2_k127_4062990_16 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000436 235.0
HKD2_k127_4062990_17 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000008205 224.0
HKD2_k127_4062990_18 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000008644 200.0
HKD2_k127_4062990_19 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000001336 198.0
HKD2_k127_4062990_2 Domain of unknown function (DUF3552) K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 579.0
HKD2_k127_4062990_20 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000003056 199.0
HKD2_k127_4062990_21 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000001004 150.0
HKD2_k127_4062990_22 Universal stress protein family - - - 0.000000000000000000000000000000000009293 141.0
HKD2_k127_4062990_23 Glycoprotease family - - - 0.000000000000000000000000000000001889 141.0
HKD2_k127_4062990_24 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000127 127.0
HKD2_k127_4062990_25 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000001183 111.0
HKD2_k127_4062990_26 Ribosome-binding factor A K02834 - - 0.00000000000000000000002994 103.0
HKD2_k127_4062990_27 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000004238 99.0
HKD2_k127_4062990_28 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000002538 100.0
HKD2_k127_4062990_29 structural constituent of ribosome K02916 - - 0.0000000000000005805 81.0
HKD2_k127_4062990_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 573.0
HKD2_k127_4062990_30 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.0000000000001418 81.0
HKD2_k127_4062990_32 Tetratricopeptide repeat - - - 0.0000001148 63.0
HKD2_k127_4062990_33 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000008791 57.0
HKD2_k127_4062990_4 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 572.0
HKD2_k127_4062990_5 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 501.0
HKD2_k127_4062990_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 501.0
HKD2_k127_4062990_7 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 471.0
HKD2_k127_4062990_8 Queuine tRNA-ribosyltransferase K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 438.0
HKD2_k127_4062990_9 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 381.0
HKD2_k127_408431_0 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 381.0
HKD2_k127_408431_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000007472 267.0
HKD2_k127_408431_2 TIGR00268 family K06864 - - 0.000000000000000000000000000000000000000000000000000000000000001349 228.0
HKD2_k127_408431_3 - - - - 0.0000000003787 71.0
HKD2_k127_408431_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000002578 49.0
HKD2_k127_4101000_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1028.0
HKD2_k127_4101000_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 420.0
HKD2_k127_4101000_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 422.0
HKD2_k127_4101000_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 336.0
HKD2_k127_4101000_4 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 325.0
HKD2_k127_4101000_5 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007809 259.0
HKD2_k127_4101000_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000002727 142.0
HKD2_k127_4101000_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000001836 104.0
HKD2_k127_4101000_8 Cobalt transport protein K16785 - - 0.00007231 54.0
HKD2_k127_4101000_9 synthase K12434 - - 0.0000892 53.0
HKD2_k127_4143133_0 type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 581.0
HKD2_k127_4143133_1 Type II secretion system (T2SS), protein F K02455,K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 342.0
HKD2_k127_4143133_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000002292 250.0
HKD2_k127_4143133_3 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000001537 141.0
HKD2_k127_4143133_4 COG2165 Type II secretory pathway, pseudopilin PulG K02456 - - 0.00000000000000000000001293 112.0
HKD2_k127_4143133_5 - - - - 0.00000000001843 74.0
HKD2_k127_4143133_6 tetratricopeptide repeat - - - 0.00008979 50.0
HKD2_k127_4243068_0 CBS domain K00974 - 2.7.7.72 1.61e-218 714.0
HKD2_k127_4243068_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 556.0
HKD2_k127_4243068_10 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000008573 258.0
HKD2_k127_4243068_11 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002951 250.0
HKD2_k127_4243068_12 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000007442 239.0
HKD2_k127_4243068_13 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000137 225.0
HKD2_k127_4243068_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000004422 210.0
HKD2_k127_4243068_15 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000006954 192.0
HKD2_k127_4243068_16 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000007483 144.0
HKD2_k127_4243068_17 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000001093 143.0
HKD2_k127_4243068_18 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000001124 147.0
HKD2_k127_4243068_19 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000001059 144.0
HKD2_k127_4243068_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 477.0
HKD2_k127_4243068_20 alginic acid biosynthetic process - - - 0.0000000000000000000000000000005289 136.0
HKD2_k127_4243068_21 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000009115 134.0
HKD2_k127_4243068_22 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000004653 110.0
HKD2_k127_4243068_23 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000002437 97.0
HKD2_k127_4243068_24 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000003335 85.0
HKD2_k127_4243068_25 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000007816 85.0
HKD2_k127_4243068_26 Protein of unknown function (DUF3467) - - - 0.00000000000000001207 86.0
HKD2_k127_4243068_27 DNA segregation ATPase, FtsK SpoIIIE family K03466 - - 0.00000000000000007448 80.0
HKD2_k127_4243068_28 Domain of unknown function (DUF1844) - - - 0.00000000001665 73.0
HKD2_k127_4243068_29 radical SAM domain protein - - - 0.00001312 58.0
HKD2_k127_4243068_3 SMART Elongator protein 3 MiaB NifB K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 411.0
HKD2_k127_4243068_4 DNA recombination K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 418.0
HKD2_k127_4243068_5 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 386.0
HKD2_k127_4243068_6 Molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 376.0
HKD2_k127_4243068_7 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 378.0
HKD2_k127_4243068_8 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 322.0
HKD2_k127_4243068_9 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 283.0
HKD2_k127_432442_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 462.0
HKD2_k127_432442_1 PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 359.0
HKD2_k127_432442_2 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 318.0
HKD2_k127_432442_3 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 307.0
HKD2_k127_432442_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000003988 168.0
HKD2_k127_4355129_0 MacB-like periplasmic core domain K02004 - - 2.241e-274 869.0
HKD2_k127_4355129_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 397.0
HKD2_k127_4355129_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000607 280.0
HKD2_k127_4355129_3 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009171 268.0
HKD2_k127_4355129_4 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006195 249.0
HKD2_k127_4355129_5 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000000002479 169.0
HKD2_k127_4355129_6 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.00000000000000000000000000000000000000005346 155.0
HKD2_k127_4355129_7 cell redox homeostasis K00384 - 1.8.1.9 0.00000000000008347 78.0
HKD2_k127_4833066_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1136.0
HKD2_k127_4833066_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 584.0
HKD2_k127_4833066_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 391.0
HKD2_k127_4833066_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 358.0
HKD2_k127_4833066_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 342.0
HKD2_k127_4833066_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 339.0
HKD2_k127_4833066_6 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 290.0
HKD2_k127_4833066_7 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000009934 204.0
HKD2_k127_4833066_8 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000001428 118.0
HKD2_k127_4942012_0 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 400.0
HKD2_k127_4942012_1 Mur ligase middle domain protein K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 389.0
HKD2_k127_4942012_2 Cache domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 345.0
HKD2_k127_4942012_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 311.0
HKD2_k127_4942012_4 Belongs to the glycosyl hydrolase 3 family K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000001562 265.0
HKD2_k127_4942012_5 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
HKD2_k127_4942012_6 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000001104 209.0
HKD2_k127_4942012_7 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K00973,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 0.0000000000000000000000000000000000000000000000000000004303 205.0
HKD2_k127_4942012_8 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000003787 184.0
HKD2_k127_4942012_9 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000004613 168.0
HKD2_k127_5019421_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 379.0
HKD2_k127_5019421_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000001774 198.0
HKD2_k127_5019421_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000001483 172.0
HKD2_k127_5019421_3 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.0000000000000000000000000000000002358 145.0
HKD2_k127_5019421_4 Beta-L-arabinofuranosidase, GH127 - - - 0.000000000000000000000000002288 125.0
HKD2_k127_5020261_0 response regulator receiver K02481,K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 356.0
HKD2_k127_5020261_1 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006637 252.0
HKD2_k127_5020261_2 Domains HAMP, HisKA, HATPase_c, REC K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000005966 248.0
HKD2_k127_5020261_3 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000858 184.0
HKD2_k127_5020261_4 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000005244 141.0
HKD2_k127_5020261_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000007891 100.0
HKD2_k127_5020261_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0008169 49.0
HKD2_k127_5140382_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 512.0
HKD2_k127_5140382_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 317.0
HKD2_k127_5140382_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001306 294.0
HKD2_k127_5140382_3 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000001339 229.0
HKD2_k127_5140382_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000003099 232.0
HKD2_k127_5140382_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000001061 176.0
HKD2_k127_5140382_6 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000006683 117.0
HKD2_k127_5140382_7 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000004723 91.0
HKD2_k127_5140382_8 NusG domain II - - - 0.0000000000000005151 89.0
HKD2_k127_5148392_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 529.0
HKD2_k127_5148392_1 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 326.0
HKD2_k127_5148392_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000004082 151.0
HKD2_k127_5148392_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000002045 55.0
HKD2_k127_5191172_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.579e-246 770.0
HKD2_k127_5191172_1 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 391.0
HKD2_k127_5191172_2 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 357.0
HKD2_k127_5191172_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
HKD2_k127_5191172_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000001224 165.0
HKD2_k127_5191172_5 PFAM Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000003389 125.0
HKD2_k127_5191172_6 Pilus assembly protein, PilP K02665 - - 0.0000000000000000006931 94.0
HKD2_k127_5191172_7 PFAM Fimbrial assembly family protein K02663 - - 0.0000000002075 73.0
HKD2_k127_5191172_8 PFAM type II and III secretion system protein K02666 - - 0.00001922 55.0
HKD2_k127_5193634_0 ABC transporter K06020 - 3.6.3.25 5.091e-290 905.0
HKD2_k127_5193634_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 430.0
HKD2_k127_5193634_2 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 334.0
HKD2_k127_5193634_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 315.0
HKD2_k127_5193634_4 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001115 281.0
HKD2_k127_5193634_5 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000003689 171.0
HKD2_k127_5193634_6 Uncharacterised protein family UPF0047 - - - 0.000000000000000003267 84.0
HKD2_k127_5201752_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 484.0
HKD2_k127_5201752_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 434.0
HKD2_k127_5201752_10 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000008026 84.0
HKD2_k127_5201752_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 376.0
HKD2_k127_5201752_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 366.0
HKD2_k127_5201752_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 340.0
HKD2_k127_5201752_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007513 287.0
HKD2_k127_5201752_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000002263 201.0
HKD2_k127_5201752_7 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000008436 186.0
HKD2_k127_5201752_8 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0000000000000000000000000000000000000004868 151.0
HKD2_k127_5201752_9 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000000000000003444 132.0
HKD2_k127_5211089_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1030.0
HKD2_k127_5211089_1 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 5.611e-252 790.0
HKD2_k127_5211089_10 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 351.0
HKD2_k127_5211089_11 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009051 248.0
HKD2_k127_5211089_12 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000003677 231.0
HKD2_k127_5211089_13 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000006861 231.0
HKD2_k127_5211089_14 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000001171 230.0
HKD2_k127_5211089_15 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000001169 191.0
HKD2_k127_5211089_16 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.0000000000000000000000000000000003784 147.0
HKD2_k127_5211089_17 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000001368 142.0
HKD2_k127_5211089_18 Protein of unknown function DUF72 - - - 0.00000000000000000000000002499 112.0
HKD2_k127_5211089_19 Rubrerythrin - - - 0.000000000000000000002852 99.0
HKD2_k127_5211089_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.277e-206 656.0
HKD2_k127_5211089_20 - - - - 0.00000000000000000329 93.0
HKD2_k127_5211089_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 553.0
HKD2_k127_5211089_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 542.0
HKD2_k127_5211089_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 461.0
HKD2_k127_5211089_6 PFAM membrane bound O-acyl transferase, MBOAT family protein K19294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 444.0
HKD2_k127_5211089_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 402.0
HKD2_k127_5211089_8 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 393.0
HKD2_k127_5211089_9 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 354.0
HKD2_k127_5228886_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000002027 232.0
HKD2_k127_5228886_1 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000001399 143.0
HKD2_k127_5228886_2 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.00000000000000000000000002088 124.0
HKD2_k127_5228886_3 COG1388 FOG LysM repeat - - - 0.000005406 57.0
HKD2_k127_5300629_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 456.0
HKD2_k127_5300629_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 321.0
HKD2_k127_5300629_2 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000001463 182.0
HKD2_k127_5300629_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000002829 171.0
HKD2_k127_5300629_4 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000000002057 160.0
HKD2_k127_5300629_5 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000001173 146.0
HKD2_k127_5300629_6 antisigma factor binding K03598 - - 0.0001634 53.0
HKD2_k127_5300629_7 AntiSigma factor - - - 0.0007687 49.0
HKD2_k127_5307200_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 3.021e-243 783.0
HKD2_k127_5307200_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.873e-226 719.0
HKD2_k127_5307200_10 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000397 269.0
HKD2_k127_5307200_11 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000006577 259.0
HKD2_k127_5307200_12 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000001906 244.0
HKD2_k127_5307200_13 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000002029 220.0
HKD2_k127_5307200_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000001341 199.0
HKD2_k127_5307200_15 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000001642 204.0
HKD2_k127_5307200_16 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000003133 177.0
HKD2_k127_5307200_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000002606 149.0
HKD2_k127_5307200_18 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000001168 128.0
HKD2_k127_5307200_19 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001775 97.0
HKD2_k127_5307200_2 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 436.0
HKD2_k127_5307200_20 Caspase domain - - - 0.0000000000000000002358 99.0
HKD2_k127_5307200_21 exodeoxyribonuclease VII activity K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000001879 67.0
HKD2_k127_5307200_22 AAA ATPase domain - - - 0.0000000003617 65.0
HKD2_k127_5307200_23 PFAM Pyruvate carboxyltransferase - - - 0.000000003487 59.0
HKD2_k127_5307200_24 DnaJ molecular chaperone homology domain - - - 0.000003555 59.0
HKD2_k127_5307200_25 Tetratricopeptide repeat - - - 0.0000331 56.0
HKD2_k127_5307200_3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 426.0
HKD2_k127_5307200_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 409.0
HKD2_k127_5307200_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006964 393.0
HKD2_k127_5307200_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 350.0
HKD2_k127_5307200_7 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 327.0
HKD2_k127_5307200_8 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 314.0
HKD2_k127_5307200_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 286.0
HKD2_k127_5311551_0 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 486.0
HKD2_k127_5311551_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 320.0
HKD2_k127_5311551_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003907 280.0
HKD2_k127_5311551_3 Rhodanese Homology Domain - - - 0.00000000000000000001379 98.0
HKD2_k127_5357403_0 COG0058 Glucan phosphorylase - - - 6.47e-240 753.0
HKD2_k127_5357403_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 314.0
HKD2_k127_5357403_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
HKD2_k127_5357403_3 heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001172 286.0
HKD2_k127_5357403_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000006799 234.0
HKD2_k127_5357403_5 Putative regulatory protein - - - 0.00000001674 63.0
HKD2_k127_5357403_6 Belongs to the UPF0235 family K09131 - - 0.00000004783 61.0
HKD2_k127_5363590_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 484.0
HKD2_k127_5363590_1 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000001995 203.0
HKD2_k127_5365081_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 5e-324 1009.0
HKD2_k127_5365081_1 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 339.0
HKD2_k127_5365081_2 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
HKD2_k127_5365081_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001148 269.0
HKD2_k127_5365081_4 pfam chad - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001669 268.0
HKD2_k127_5365081_5 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000002966 226.0
HKD2_k127_5365081_6 triphosphatase activity K01768 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0050355 4.6.1.1 0.00000000000000000000000000000000000000000000000001323 184.0
HKD2_k127_5365081_7 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000005607 135.0
HKD2_k127_5365081_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000002846 128.0
HKD2_k127_5365081_9 MerR HTH family regulatory protein - - - 0.0000000001963 70.0
HKD2_k127_5404191_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 585.0
HKD2_k127_5404191_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 389.0
HKD2_k127_5404191_10 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000002208 143.0
HKD2_k127_5404191_11 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000002232 114.0
HKD2_k127_5404191_12 chlorophyll binding K16191,K20276 - - 0.0000000000000000000001294 108.0
HKD2_k127_5404191_13 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02784,K03488,K05881,K08483,K11183,K11184,K11189,K11201 GO:0003674,GO:0003824,GO:0005215,GO:0005353,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005981,GO:0006109,GO:0006464,GO:0006476,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006950,GO:0006974,GO:0008047,GO:0008150,GO:0008152,GO:0008643,GO:0008645,GO:0008965,GO:0008982,GO:0009401,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015144,GO:0015145,GO:0015149,GO:0015749,GO:0015755,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0018193,GO:0018205,GO:0019197,GO:0019213,GO:0019222,GO:0019538,GO:0019897,GO:0019898,GO:0022804,GO:0022857,GO:0022877,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032445,GO:0032881,GO:0032991,GO:0033554,GO:0033558,GO:0034219,GO:0034983,GO:0035601,GO:0036211,GO:0043085,GO:0043170,GO:0043412,GO:0043467,GO:0043470,GO:0043471,GO:0043610,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045819,GO:0045913,GO:0047324,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051119,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060255,GO:0062012,GO:0062013,GO:0065007,GO:0065009,GO:0070873,GO:0070875,GO:0071702,GO:0071704,GO:0071944,GO:0080090,GO:0090563,GO:0098732,GO:0098772,GO:0140096,GO:1901564 2.7.1.121,2.7.1.202,2.7.3.9 0.00000000000000000001156 98.0
HKD2_k127_5404191_14 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000001547 87.0
HKD2_k127_5404191_15 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.000000000004727 74.0
HKD2_k127_5404191_16 Protein conserved in bacteria K11719 - - 0.0004032 51.0
HKD2_k127_5404191_2 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 322.0
HKD2_k127_5404191_3 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 316.0
HKD2_k127_5404191_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 315.0
HKD2_k127_5404191_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000961 280.0
HKD2_k127_5404191_6 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002416 276.0
HKD2_k127_5404191_7 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 259.0
HKD2_k127_5404191_8 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000007292 236.0
HKD2_k127_5404191_9 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000003053 160.0
HKD2_k127_5475269_0 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 445.0
HKD2_k127_5475269_1 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 287.0
HKD2_k127_5475269_2 PFAM Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000003023 241.0
HKD2_k127_5475269_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000001561 222.0
HKD2_k127_5475269_4 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000002964 210.0
HKD2_k127_5475269_5 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000003567 174.0
HKD2_k127_5475269_6 Bacterial SH3 domain homologues - - - 0.000000000000000000005233 98.0
HKD2_k127_5491711_0 DEAD DEAH box helicase K06877 - - 2.41e-281 899.0
HKD2_k127_5491711_1 PFAM Carbamoyltransferase K00612 - - 4.219e-267 841.0
HKD2_k127_5491711_10 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003523 246.0
HKD2_k127_5491711_11 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000001614 213.0
HKD2_k127_5491711_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000001399 181.0
HKD2_k127_5491711_13 methyltransferase K00563,K10947 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008270,GO:0008649,GO:0008757,GO:0008989,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0052912,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.187 0.00000000000000000000000000000000000000000004195 172.0
HKD2_k127_5491711_14 proteolysis - - - 0.000000000000000000002913 102.0
HKD2_k127_5491711_15 - - - - 0.0000000000000006994 80.0
HKD2_k127_5491711_16 - - - - 0.00000001067 63.0
HKD2_k127_5491711_17 Endonuclease/Exonuclease/phosphatase family - - - 0.0000009537 55.0
HKD2_k127_5491711_2 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 581.0
HKD2_k127_5491711_3 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 453.0
HKD2_k127_5491711_4 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 419.0
HKD2_k127_5491711_5 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 373.0
HKD2_k127_5491711_6 Efflux ABC transporter permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 361.0
HKD2_k127_5491711_7 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 326.0
HKD2_k127_5491711_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007217 280.0
HKD2_k127_5491711_9 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004786 276.0
HKD2_k127_5493750_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 6.205e-206 667.0
HKD2_k127_5493750_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.361e-194 617.0
HKD2_k127_5493750_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 359.0
HKD2_k127_5493750_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000002476 233.0
HKD2_k127_5493750_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000001986 206.0
HKD2_k127_5493750_5 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000000000009763 171.0
HKD2_k127_5493750_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000001668 164.0
HKD2_k127_5493750_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000002093 132.0
HKD2_k127_5493750_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000003736 110.0
HKD2_k127_5493750_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00004701 55.0
HKD2_k127_5601217_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1120.0
HKD2_k127_5601217_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 474.0
HKD2_k127_5601217_10 COG1413 FOG HEAT repeat - - - 0.00006354 54.0
HKD2_k127_5601217_2 Radical SAM K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 423.0
HKD2_k127_5601217_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001946 279.0
HKD2_k127_5601217_4 PFAM iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000003168 179.0
HKD2_k127_5601217_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000005076 171.0
HKD2_k127_5601217_6 Histidine kinase K02491,K07698 - 2.7.13.3 0.00000000000000000000000000000000000001524 159.0
HKD2_k127_5601217_7 PFAM response regulator receiver - - - 0.00000000000000000000000001078 116.0
HKD2_k127_5601217_8 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000001348 86.0
HKD2_k127_5601217_9 Tetratricopeptide repeat - - - 0.00000000008467 70.0
HKD2_k127_5648413_0 Sigma-54 interaction domain K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 442.0
HKD2_k127_5648413_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000001926 159.0
HKD2_k127_5648413_2 cobalamin synthesis protein, P47K - - - 0.0000000000000000000000000000000000000006838 162.0
HKD2_k127_5648413_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000000000000000000001446 158.0
HKD2_k127_5648413_4 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000002745 156.0
HKD2_k127_5648413_5 PFAM response regulator receiver - - - 0.0004719 48.0
HKD2_k127_5651730_0 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 1.505e-225 711.0
HKD2_k127_5651730_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.401e-211 673.0
HKD2_k127_5651730_2 SMART molybdopterin oxidoreductase Fe4S4 region, NADH ubiquinone oxidoreductase, subunit G, iron-sulfur binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 475.0
HKD2_k127_5651730_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002437 213.0
HKD2_k127_5651730_4 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000008405 134.0
HKD2_k127_5651730_5 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.0000000000000000000000000003722 116.0
HKD2_k127_5664575_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 552.0
HKD2_k127_5664575_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 419.0
HKD2_k127_5664575_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000006548 174.0
HKD2_k127_5664575_3 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000829 146.0
HKD2_k127_5664575_4 Thioredoxin - - - 0.0001742 47.0
HKD2_k127_5698076_0 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 3.928e-198 630.0
HKD2_k127_5698076_1 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008136 258.0
HKD2_k127_5698076_2 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000001058 243.0
HKD2_k127_5698076_3 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000002575 214.0
HKD2_k127_5698076_4 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000001491 194.0
HKD2_k127_5698076_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000007054 167.0
HKD2_k127_5698076_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000000000000000000000000796 165.0
HKD2_k127_5698076_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001979 114.0
HKD2_k127_5698076_8 Sulfurtransferase TusA - - - 0.0000000000000000000002882 99.0
HKD2_k127_5912411_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 9.968e-206 661.0
HKD2_k127_5912411_1 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 298.0
HKD2_k127_5912411_3 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000001858 160.0
HKD2_k127_5912411_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000001536 132.0
HKD2_k127_5912411_5 - - - - 0.0000000000000000000000000001326 123.0
HKD2_k127_5912411_6 Late competence development protein ComFB - - - 0.00001913 54.0
HKD2_k127_6014159_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 4.189e-250 805.0
HKD2_k127_6014159_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 419.0
HKD2_k127_6014159_10 lipolytic protein G-D-S-L family - - - 0.0000007085 62.0
HKD2_k127_6014159_11 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000001418 56.0
HKD2_k127_6014159_12 Protein of unknown function (DUF433) - - - 0.00001271 48.0
HKD2_k127_6014159_2 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 368.0
HKD2_k127_6014159_3 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 316.0
HKD2_k127_6014159_4 HD domain - - - 0.000000000000000000000000000000000000000000000004187 177.0
HKD2_k127_6014159_5 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000001087 171.0
HKD2_k127_6014159_6 PIN domain - - - 0.0000000000000000000000000006561 123.0
HKD2_k127_6014159_7 NifU-like domain - - - 0.000000000000000000000000002579 113.0
HKD2_k127_6014159_8 response to nickel cation K07723 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000001386 92.0
HKD2_k127_6014159_9 - - - - 0.000000001071 61.0
HKD2_k127_6053002_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 453.0
HKD2_k127_6053002_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 449.0
HKD2_k127_6053002_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 316.0
HKD2_k127_6053002_3 TIGRFAM formate dehydrogenase, alpha subunit K00123,K00336,K05299 - 1.17.1.10,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 316.0
HKD2_k127_6053002_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000008263 143.0
HKD2_k127_6053002_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000002482 128.0
HKD2_k127_6075173_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001608 273.0
HKD2_k127_6075173_1 Transglycosylase SLT domain K08307,K12204 - - 0.0000000000000000000000000000000005098 146.0
HKD2_k127_6075173_2 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000001422 123.0
HKD2_k127_6194280_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007345 290.0
HKD2_k127_6194280_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000002292 229.0
HKD2_k127_6194280_2 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000002651 139.0
HKD2_k127_6194280_3 domain, Protein - - - 0.0000000001456 70.0
HKD2_k127_6199398_0 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 524.0
HKD2_k127_6199398_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000001976 144.0
HKD2_k127_637209_0 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 529.0
HKD2_k127_637209_1 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 507.0
HKD2_k127_637209_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 338.0
HKD2_k127_637209_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 313.0
HKD2_k127_637209_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000007723 250.0
HKD2_k127_637209_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000001374 126.0
HKD2_k127_637209_6 Tetratricopeptide repeat - - - 0.0000000000018 82.0
HKD2_k127_637209_7 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000001082 65.0
HKD2_k127_6425675_0 helicase activity - - - 2.075e-309 969.0
HKD2_k127_6425675_1 Domain of unknown function (DUF4139) - - - 1.989e-236 752.0
HKD2_k127_6425675_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000006395 143.0
HKD2_k127_6425675_11 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000133 153.0
HKD2_k127_6425675_12 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.00000000000000000000000000001998 136.0
HKD2_k127_6425675_13 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000000000000002682 128.0
HKD2_k127_6425675_14 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000004281 111.0
HKD2_k127_6425675_15 Type II secretion system protein B K02451 - - 0.00000000000000001558 94.0
HKD2_k127_6425675_16 - - - - 0.000000000006031 66.0
HKD2_k127_6425675_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 518.0
HKD2_k127_6425675_3 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 491.0
HKD2_k127_6425675_4 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 443.0
HKD2_k127_6425675_5 Type II secretory pathway component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 412.0
HKD2_k127_6425675_6 PFAM Radical SAM K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 354.0
HKD2_k127_6425675_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 318.0
HKD2_k127_6425675_8 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000002346 198.0
HKD2_k127_6425675_9 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000444 194.0
HKD2_k127_6487721_0 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 509.0
HKD2_k127_6487721_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 307.0
HKD2_k127_6487721_2 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000001193 243.0
HKD2_k127_6487721_3 twitching motility protein K02669 - - 0.00000000000000000000000000000000148 131.0
HKD2_k127_6510378_0 General secretory system II, protein E domain protein K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 590.0
HKD2_k127_6510378_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 543.0
HKD2_k127_6510378_10 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000000000003224 113.0
HKD2_k127_6510378_11 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000323 115.0
HKD2_k127_6510378_12 Tetratricopeptide repeat K05807 - - 0.000000000000000000002374 104.0
HKD2_k127_6510378_13 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000311 78.0
HKD2_k127_6510378_14 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000001072 77.0
HKD2_k127_6510378_15 cluster protein-associated redox disulfide domain - - - 0.000000000008768 68.0
HKD2_k127_6510378_16 COG0835 Chemotaxis signal transduction protein K03408 - - 0.0000000001874 68.0
HKD2_k127_6510378_17 Transcriptional regulatory protein, C terminal - - - 0.000008698 57.0
HKD2_k127_6510378_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 528.0
HKD2_k127_6510378_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 385.0
HKD2_k127_6510378_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000001515 214.0
HKD2_k127_6510378_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000008564 193.0
HKD2_k127_6510378_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000007913 177.0
HKD2_k127_6510378_7 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000008665 163.0
HKD2_k127_6510378_8 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000003206 157.0
HKD2_k127_6510378_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000001333 135.0
HKD2_k127_6570742_0 DEAD DEAH box helicase K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 424.0
HKD2_k127_6570742_1 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 334.0
HKD2_k127_6570742_10 HNH nucleases - - - 0.00000000000000000000000000000000000003554 146.0
HKD2_k127_6570742_11 1,4-alpha-glucan branching enzyme activity - - - 0.0000000000000000000000000000001493 130.0
HKD2_k127_6570742_12 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00001262 49.0
HKD2_k127_6570742_2 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001246 268.0
HKD2_k127_6570742_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003265 260.0
HKD2_k127_6570742_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003839 241.0
HKD2_k127_6570742_5 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000007634 222.0
HKD2_k127_6570742_6 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000005649 223.0
HKD2_k127_6570742_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000001771 202.0
HKD2_k127_6570742_8 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000001347 203.0
HKD2_k127_6570742_9 SpoU rRNA Methylase family K03437 - - 0.00000000000000000000000000000000000000000428 166.0
HKD2_k127_6582188_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 4.311e-311 972.0
HKD2_k127_6582188_1 PFAM Acetyl-CoA hydrolase transferase - - - 3.772e-282 882.0
HKD2_k127_6582188_2 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 338.0
HKD2_k127_6582188_3 PEP-utilising enzyme, N-terminal K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000008253 247.0
HKD2_k127_6582188_4 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000001097 165.0
HKD2_k127_6582188_5 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000000000000005066 132.0
HKD2_k127_6582188_6 Zincin-like metallopeptidase - - - 0.0000000000000000000000000002391 122.0
HKD2_k127_6582188_7 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.000000000000000000000001174 110.0
HKD2_k127_6590363_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 304.0
HKD2_k127_6590363_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000004612 188.0
HKD2_k127_6590363_2 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000004982 192.0
HKD2_k127_6590363_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00001094 48.0
HKD2_k127_6625319_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 533.0
HKD2_k127_6625319_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 496.0
HKD2_k127_6625319_10 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000008115 133.0
HKD2_k127_6625319_11 - - - - 0.000000000000000000000000005504 124.0
HKD2_k127_6625319_12 Outer membrane efflux protein - - - 0.0000000000000000000000003527 122.0
HKD2_k127_6625319_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 398.0
HKD2_k127_6625319_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 317.0
HKD2_k127_6625319_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 312.0
HKD2_k127_6625319_5 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004539 278.0
HKD2_k127_6625319_6 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005873 268.0
HKD2_k127_6625319_7 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002363 257.0
HKD2_k127_6625319_8 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000000000000000000000000000000000000007357 246.0
HKD2_k127_6625319_9 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000007232 194.0
HKD2_k127_6626553_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 467.0
HKD2_k127_6626553_1 Bacterial type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 349.0
HKD2_k127_6626553_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000063 134.0
HKD2_k127_6626553_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000005934 90.0
HKD2_k127_6626553_4 Type II secretion system (T2SS), protein M subtype b - - - 0.0000000001842 70.0
HKD2_k127_6626553_5 PFAM Fimbrial assembly family protein K02461 - - 0.000000713 62.0
HKD2_k127_6626553_6 general secretion pathway protein K02458 - - 0.0002032 50.0
HKD2_k127_6681618_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.407e-245 764.0
HKD2_k127_6681618_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001219 279.0
HKD2_k127_6681618_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008253 283.0
HKD2_k127_6681618_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000001044 194.0
HKD2_k127_6789684_0 FtsX-like permease family K02004 - - 5.718e-255 806.0
HKD2_k127_6789684_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 490.0
HKD2_k127_6789684_2 TIGRFAM DNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 330.0
HKD2_k127_6789684_3 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004006 290.0
HKD2_k127_6789684_4 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000000000000000000000000000000006237 206.0
HKD2_k127_6789684_5 Papain-like cysteine protease AvrRpt2 - - - 0.0000000000000000000000002718 117.0
HKD2_k127_6789684_6 Tetratricopeptide repeat - - - 0.0000000000000000000007917 105.0
HKD2_k127_6789684_7 - - - - 0.00000000000007417 77.0
HKD2_k127_6814922_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 564.0
HKD2_k127_6814922_1 rRNA (cytosine-N4-)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 547.0
HKD2_k127_6814922_10 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 275.0
HKD2_k127_6814922_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000006473 266.0
HKD2_k127_6814922_12 Macro domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001422 222.0
HKD2_k127_6814922_13 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000004836 230.0
HKD2_k127_6814922_14 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000001586 231.0
HKD2_k127_6814922_15 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000002566 188.0
HKD2_k127_6814922_16 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000007884 181.0
HKD2_k127_6814922_17 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000000000000000000000000000006934 168.0
HKD2_k127_6814922_18 Cell division protein FtsQ K03589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000004866 80.0
HKD2_k127_6814922_19 - - - - 0.0006629 48.0
HKD2_k127_6814922_2 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 518.0
HKD2_k127_6814922_3 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 473.0
HKD2_k127_6814922_4 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 430.0
HKD2_k127_6814922_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 433.0
HKD2_k127_6814922_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 403.0
HKD2_k127_6814922_7 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 387.0
HKD2_k127_6814922_8 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 324.0
HKD2_k127_6814922_9 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001664 276.0
HKD2_k127_6856987_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 1.906e-269 855.0
HKD2_k127_6856987_1 Chase2 domain K01768,K07814 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 565.0
HKD2_k127_6856987_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000005169 178.0
HKD2_k127_6856987_11 PFAM nuclease (SNase domain protein) - - - 0.00000000000000000000000000000000000002438 151.0
HKD2_k127_6856987_12 chlorophyll binding K03286 - - 0.0000000000000000000000000000000000001118 149.0
HKD2_k127_6856987_13 FecR protein - - - 0.00000000000000000000000000000000002642 141.0
HKD2_k127_6856987_14 RNA recognition motif - - - 0.0000000000000000000000001591 110.0
HKD2_k127_6856987_15 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000002914 102.0
HKD2_k127_6856987_16 aminopeptidase N - - - 0.0000000000000009699 90.0
HKD2_k127_6856987_17 general secretion pathway protein - - - 0.0000002914 59.0
HKD2_k127_6856987_2 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 554.0
HKD2_k127_6856987_3 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 470.0
HKD2_k127_6856987_4 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 445.0
HKD2_k127_6856987_5 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 383.0
HKD2_k127_6856987_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000004173 242.0
HKD2_k127_6856987_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000007077 243.0
HKD2_k127_6856987_8 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001015 228.0
HKD2_k127_6856987_9 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000005487 204.0
HKD2_k127_6871488_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004269 293.0
HKD2_k127_6871488_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000001005 257.0
HKD2_k127_6871488_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000212 231.0
HKD2_k127_6871488_3 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
HKD2_k127_6871488_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000001188 174.0
HKD2_k127_6871488_5 Binds directly to 16S ribosomal RNA K02968 - - 0.0000005593 55.0
HKD2_k127_7035722_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1105.0
HKD2_k127_7035722_1 PFAM cytochrome bd ubiquinol oxidase, subunit I K00425 - 1.10.3.14 9.551e-201 635.0
HKD2_k127_7035722_10 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 349.0
HKD2_k127_7035722_11 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 358.0
HKD2_k127_7035722_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 368.0
HKD2_k127_7035722_13 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 298.0
HKD2_k127_7035722_14 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 291.0
HKD2_k127_7035722_15 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000009271 272.0
HKD2_k127_7035722_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001546 271.0
HKD2_k127_7035722_17 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009166 271.0
HKD2_k127_7035722_18 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002305 265.0
HKD2_k127_7035722_19 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000003488 247.0
HKD2_k127_7035722_2 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 3.233e-194 616.0
HKD2_k127_7035722_20 Putative NAD(P)-binding K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003651 244.0
HKD2_k127_7035722_21 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000001715 247.0
HKD2_k127_7035722_22 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000002286 239.0
HKD2_k127_7035722_23 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000469 233.0
HKD2_k127_7035722_24 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001461 222.0
HKD2_k127_7035722_25 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001175 230.0
HKD2_k127_7035722_26 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000303 225.0
HKD2_k127_7035722_27 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000002732 213.0
HKD2_k127_7035722_28 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000001743 213.0
HKD2_k127_7035722_29 PFAM toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000000000000000001989 189.0
HKD2_k127_7035722_3 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 581.0
HKD2_k127_7035722_30 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000000000000000000003051 179.0
HKD2_k127_7035722_31 LexA DNA binding domain K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000006553 177.0
HKD2_k127_7035722_32 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000000004494 179.0
HKD2_k127_7035722_33 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000003314 171.0
HKD2_k127_7035722_34 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000001924 169.0
HKD2_k127_7035722_35 PFAM cytoplasmic chaperone TorD family protein - - - 0.000000000000000000000000000000000000001231 165.0
HKD2_k127_7035722_36 membrane K15977 - - 0.000000000000000000000000000000000007821 140.0
HKD2_k127_7035722_37 amine dehydrogenase activity - - - 0.00000000000000000000000000000000467 146.0
HKD2_k127_7035722_38 - - - - 0.00000000000000000000000000003238 120.0
HKD2_k127_7035722_39 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000000000000001083 118.0
HKD2_k127_7035722_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 458.0
HKD2_k127_7035722_40 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000665 106.0
HKD2_k127_7035722_41 Cytochrome C1 family K00413 - - 0.00000000000000002325 96.0
HKD2_k127_7035722_42 Thioredoxin domain - - - 0.000000000000007913 76.0
HKD2_k127_7035722_43 PFAM Disulphide bond isomerase, DsbC G-like K03981 - 5.3.4.1 0.0000000008663 64.0
HKD2_k127_7035722_44 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000001358 56.0
HKD2_k127_7035722_45 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00003435 52.0
HKD2_k127_7035722_46 FAD binding domain K05712 - 1.14.13.127 0.00005392 54.0
HKD2_k127_7035722_5 3-dehydroquinate synthase K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 426.0
HKD2_k127_7035722_6 TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 415.0
HKD2_k127_7035722_7 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 391.0
HKD2_k127_7035722_8 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 383.0
HKD2_k127_7035722_9 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 362.0
HKD2_k127_7236831_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008034 521.0
HKD2_k127_7236831_1 - K16923 - - 0.00000000000000000000000000000000000000000000000000000006766 225.0
HKD2_k127_7236831_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000002913 203.0
HKD2_k127_7236831_3 histidine kinase HAMP region domain protein K07710 - 2.7.13.3 0.00000000000000000000000002258 110.0
HKD2_k127_7236831_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000002326 112.0
HKD2_k127_7236831_5 diguanylate cyclase - - - 0.000000000000003757 89.0
HKD2_k127_7477843_0 UPF0313 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 563.0
HKD2_k127_7477843_1 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 477.0
HKD2_k127_7477843_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 306.0
HKD2_k127_7477843_3 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004331 239.0
HKD2_k127_7477843_4 NADH dehydrogenase K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
HKD2_k127_7699462_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000001238 206.0
HKD2_k127_7699462_1 Surface antigen K07277 - - 0.000000000000000000000000000000000000000001117 167.0
HKD2_k127_7699462_2 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000002664 111.0
HKD2_k127_7699462_3 long-chain fatty acid transporting porin activity K06076 - - 0.00009404 53.0
HKD2_k127_7764042_0 PFAM FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 356.0
HKD2_k127_7764042_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 324.0
HKD2_k127_7764042_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 286.0
HKD2_k127_7764042_3 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000366 191.0
HKD2_k127_7764042_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000009436 160.0
HKD2_k127_7778147_0 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 316.0
HKD2_k127_7778147_1 PFAM von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001157 255.0
HKD2_k127_7778147_2 PFAM von Willebrand factor type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000006135 218.0
HKD2_k127_7778147_3 - - - - 0.0000000000000000000007727 108.0
HKD2_k127_7819244_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 550.0
HKD2_k127_7819244_1 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 328.0
HKD2_k127_7819244_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005492 268.0
HKD2_k127_7819244_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000009924 234.0
HKD2_k127_7819244_4 Protein of unknown function DUF58 - - - 0.000000000000000000000001132 117.0
HKD2_k127_7822489_0 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009576 288.0
HKD2_k127_7822489_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000003968 249.0
HKD2_k127_7822489_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000009636 63.0
HKD2_k127_7822489_3 Tetratricopeptide repeat - - - 0.000007772 53.0
HKD2_k127_7871303_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000002619 164.0
HKD2_k127_7871303_1 Surface antigen K07277 - - 0.00000000000000000000000000000009157 144.0
HKD2_k127_7871303_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000007717 93.0
HKD2_k127_7935830_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 3.464e-254 794.0
HKD2_k127_7935830_1 GXGXG motif - - - 2.001e-245 777.0
HKD2_k127_7935830_10 Bacterial extracellular solute-binding protein K10938 - - 0.000000000000000000000000000000000000000000007404 173.0
HKD2_k127_7935830_11 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000000002478 147.0
HKD2_k127_7935830_12 - - - - 0.000000000000000000000000000000000001641 139.0
HKD2_k127_7935830_13 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000005889 121.0
HKD2_k127_7935830_14 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000419 91.0
HKD2_k127_7935830_15 Esterase PHB depolymerase - - - 0.0000000000835 77.0
HKD2_k127_7935830_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.351e-203 672.0
HKD2_k127_7935830_3 HRDC domain protein K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 365.0
HKD2_k127_7935830_4 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 321.0
HKD2_k127_7935830_5 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
HKD2_k127_7935830_6 domain, Protein K15125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 329.0
HKD2_k127_7935830_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000005986 224.0
HKD2_k127_7935830_8 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000000000000000000000000004036 209.0
HKD2_k127_7935830_9 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.00000000000000000000000000000000000000000000000000006869 191.0
HKD2_k127_7998800_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009996 477.0
HKD2_k127_7998800_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 353.0
HKD2_k127_7998800_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 299.0
HKD2_k127_7998800_3 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009267 281.0
HKD2_k127_7998800_4 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005908 258.0
HKD2_k127_7998800_5 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000002932 205.0
HKD2_k127_7998800_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000005048 171.0
HKD2_k127_7998800_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000001185 104.0
HKD2_k127_7998800_8 Glycosyl transferases group 1 - - - 0.00000000006243 75.0
HKD2_k127_8134958_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.596e-212 686.0
HKD2_k127_8134958_1 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 316.0
HKD2_k127_8134958_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000001693 171.0
HKD2_k127_8134958_3 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000008442 65.0
HKD2_k127_8222121_0 PFAM HhH-GPD family protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002519 261.0
HKD2_k127_8222121_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000003096 197.0
HKD2_k127_8222121_2 PFAM UvrD REP helicase K03656,K03657 - 3.6.4.12 0.00000000000000000000000000000000001115 142.0
HKD2_k127_8222121_3 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000005491 108.0
HKD2_k127_8222121_4 epimerase dehydratase K07071 - - 0.00000000000001046 77.0
HKD2_k127_8457391_0 DNA polymerase A domain K02335 - 2.7.7.7 1.456e-299 946.0
HKD2_k127_8457391_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008713 595.0
HKD2_k127_8457391_10 Lysin motif - - - 0.0003125 53.0
HKD2_k127_8457391_2 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 366.0
HKD2_k127_8457391_3 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 338.0
HKD2_k127_8457391_4 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008719 281.0
HKD2_k127_8457391_5 PFAM FAD dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008887 259.0
HKD2_k127_8457391_6 Polysaccharide deacetylase K11931 - - 0.000000000000000000000000000000000000000000000000000005386 198.0
HKD2_k127_8457391_8 - - - - 0.0000411 52.0
HKD2_k127_864639_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 501.0
HKD2_k127_864639_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 438.0
HKD2_k127_864639_10 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000015 231.0
HKD2_k127_864639_11 ResB-like family - - - 0.000000000000000000000000000000000000000000000000000000005222 207.0
HKD2_k127_864639_12 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000001169 194.0
HKD2_k127_864639_13 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000001051 181.0
HKD2_k127_864639_14 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000001841 174.0
HKD2_k127_864639_15 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000007277 172.0
HKD2_k127_864639_16 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000000000003252 154.0
HKD2_k127_864639_17 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000792 140.0
HKD2_k127_864639_18 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000000000000000367 127.0
HKD2_k127_864639_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 455.0
HKD2_k127_864639_20 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000005673 114.0
HKD2_k127_864639_21 Thioredoxin-like - - - 0.0000000000000000000000009223 117.0
HKD2_k127_864639_22 - - - - 0.00000000000003842 84.0
HKD2_k127_864639_23 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.000000000000225 79.0
HKD2_k127_864639_24 - - - - 0.000000005418 61.0
HKD2_k127_864639_26 Putative prokaryotic signal transducing protein - - - 0.0002602 51.0
HKD2_k127_864639_27 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0008255 51.0
HKD2_k127_864639_3 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 450.0
HKD2_k127_864639_4 PFAM Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 387.0
HKD2_k127_864639_5 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 346.0
HKD2_k127_864639_6 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004576 268.0
HKD2_k127_864639_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000008314 271.0
HKD2_k127_864639_8 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009768 263.0
HKD2_k127_864639_9 MafB19-like deaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004449 253.0
HKD2_k127_883504_0 BadF BadG BcrA BcrD - - - 0.0 1146.0
HKD2_k127_883504_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 392.0
HKD2_k127_883504_2 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000002666 196.0
HKD2_k127_883504_3 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000003506 120.0
HKD2_k127_883504_4 Tetratricopeptide repeat - - - 0.00000000000006001 80.0
HKD2_k127_8944048_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.091e-204 661.0
HKD2_k127_8944048_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 601.0
HKD2_k127_8944048_10 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002474 261.0
HKD2_k127_8944048_11 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000145 225.0
HKD2_k127_8944048_12 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000002235 235.0
HKD2_k127_8944048_13 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000001946 223.0
HKD2_k127_8944048_14 Fibronectin-binding A domain protein - - - 0.000000000000000000000000000000000000000000000000000002018 212.0
HKD2_k127_8944048_15 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000009123 187.0
HKD2_k127_8944048_16 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000001051 166.0
HKD2_k127_8944048_17 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000002106 146.0
HKD2_k127_8944048_18 5'-nucleotidase - - - 0.000000000000000000000000000000003964 143.0
HKD2_k127_8944048_19 - - - - 0.00000000000000000000000000000001907 130.0
HKD2_k127_8944048_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 601.0
HKD2_k127_8944048_20 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000000000008307 117.0
HKD2_k127_8944048_21 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000009144 122.0
HKD2_k127_8944048_22 response regulator receiver K02490 - - 0.00000000000000000459 91.0
HKD2_k127_8944048_23 Belongs to the SpoVG family K06412 - - 0.0000000000000008669 83.0
HKD2_k127_8944048_24 Late competence development protein ComFB K02241 - - 0.0000000008194 69.0
HKD2_k127_8944048_25 YacP-like NYN domain K06962 - - 0.0000004876 61.0
HKD2_k127_8944048_3 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 582.0
HKD2_k127_8944048_4 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 572.0
HKD2_k127_8944048_5 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 458.0
HKD2_k127_8944048_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 372.0
HKD2_k127_8944048_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 355.0
HKD2_k127_8944048_8 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 312.0
HKD2_k127_8944048_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000129 284.0
HKD2_k127_8946014_0 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 328.0
HKD2_k127_8946014_1 chorismate binding enzyme K02552,K14759 - 2.2.1.9,4.2.1.113,4.2.99.20,5.4.4.2 0.0000000000000000000000000000000000000005726 158.0
HKD2_k127_8946014_2 PFAM thioesterase superfamily K12073 - 3.1.2.28 0.000000000000000000000000001044 117.0
HKD2_k127_8946014_3 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000000005367 73.0
HKD2_k127_8946014_4 Domain of unknown function (DUF4340) - - - 0.0002281 52.0
HKD2_k127_8946014_5 ABC-type uncharacterized transport system - - - 0.0005539 47.0
HKD2_k127_8976238_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 365.0
HKD2_k127_8976238_1 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 359.0
HKD2_k127_8976238_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 344.0
HKD2_k127_8976238_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 341.0
HKD2_k127_8976238_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 312.0
HKD2_k127_8976238_5 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002738 267.0
HKD2_k127_8976238_6 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007599 273.0
HKD2_k127_8976238_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000001119 220.0
HKD2_k127_8996674_0 UvrD/REP helicase N-terminal domain - - - 1.195e-235 769.0
HKD2_k127_8996674_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.158e-231 748.0
HKD2_k127_8996674_2 exonuclease activity K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 590.0
HKD2_k127_8996674_3 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 413.0
HKD2_k127_8996674_4 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 389.0
HKD2_k127_8996674_5 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 372.0
HKD2_k127_8996674_6 protein kinase activity - - - 0.00000000000000000000000000000008808 144.0
HKD2_k127_8996674_7 PFAM ABC transporter related K02003 - - 0.00000000000000000000000008708 108.0
HKD2_k127_8996674_8 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000001058 77.0
HKD2_k127_8996674_9 Wd-40 repeat - - - 0.0000352 53.0
HKD2_k127_9000115_0 Hydrolase carbon-nitrogen family - - - 0.00000000000000000000000000000000000000000000000000008765 196.0
HKD2_k127_9000115_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000006449 173.0
HKD2_k127_9000115_2 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000002989 144.0
HKD2_k127_9028340_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 357.0
HKD2_k127_9028340_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
HKD2_k127_9028340_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 325.0
HKD2_k127_9028340_3 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 322.0
HKD2_k127_9028340_4 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 303.0
HKD2_k127_9028340_5 transport, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001863 287.0
HKD2_k127_9028340_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000001051 239.0
HKD2_k127_9028340_7 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000000007419 191.0
HKD2_k127_9028340_8 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000002482 114.0
HKD2_k127_9028340_9 PspC domain - - - 0.0000000000284 66.0
HKD2_k127_9071290_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009494 565.0
HKD2_k127_9071290_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 339.0
HKD2_k127_9071290_10 TIGRFAM molybdenum cofactor synthesis domain - - - 0.000000000004197 76.0
HKD2_k127_9071290_11 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000008764 70.0
HKD2_k127_9071290_12 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0001318 46.0
HKD2_k127_9071290_2 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001044 278.0
HKD2_k127_9071290_3 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005962 258.0
HKD2_k127_9071290_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000007926 222.0
HKD2_k127_9071290_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000005715 213.0
HKD2_k127_9071290_6 Permease YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000008204 208.0
HKD2_k127_9071290_7 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000002072 177.0
HKD2_k127_9071290_8 rRNA binding K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001341 150.0
HKD2_k127_9071290_9 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000004921 136.0
HKD2_k127_9090982_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 366.0
HKD2_k127_9090982_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000007143 248.0
HKD2_k127_9090982_10 NosL K19342 - - 0.0000003261 62.0
HKD2_k127_9090982_11 methyltransferase - - - 0.0000004281 61.0
HKD2_k127_9090982_12 PFAM DsrE K07235 - - 0.0000283 51.0
HKD2_k127_9090982_13 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.00005114 50.0
HKD2_k127_9090982_14 Domain of unknown function (DUF4418) - - - 0.00008035 51.0
HKD2_k127_9090982_2 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000001258 237.0
HKD2_k127_9090982_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000002014 236.0
HKD2_k127_9090982_4 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000001036 194.0
HKD2_k127_9090982_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.00000000000000000000000000000000457 148.0
HKD2_k127_9090982_6 Transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000001842 126.0
HKD2_k127_9090982_7 CS domain K13993 - - 0.0000000000000000000004188 102.0
HKD2_k127_9090982_8 Belongs to the sulfur carrier protein TusA family - - - 0.00000000006932 70.0
HKD2_k127_9090982_9 FtsX-like permease family K02004 - - 0.0000000001112 64.0
HKD2_k127_9103778_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 308.0
HKD2_k127_9103778_1 Redoxin - - - 0.0004607 52.0
HKD2_k127_9183807_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 513.0
HKD2_k127_9183807_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 446.0
HKD2_k127_9183807_2 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 448.0
HKD2_k127_9183807_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 311.0
HKD2_k127_9183807_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 277.0
HKD2_k127_9183807_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
HKD2_k127_9183807_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000002636 228.0
HKD2_k127_9183807_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000005298 209.0
HKD2_k127_9183807_8 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000003997 115.0
HKD2_k127_9183807_9 Putative regulatory protein - - - 0.0000000272 63.0
HKD2_k127_9189902_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 448.0
HKD2_k127_9189902_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 412.0
HKD2_k127_9189902_2 formate dehydrogenase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 356.0
HKD2_k127_9189902_3 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 321.0
HKD2_k127_9189902_4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006823 281.0
HKD2_k127_9189902_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000001159 153.0
HKD2_k127_9189902_6 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000002031 153.0
HKD2_k127_9189902_7 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.0000000000000000000000000000001859 123.0
HKD2_k127_9189902_8 COG1622 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.00000752 52.0
HKD2_k127_9189902_9 VWA domain containing CoxE-like protein K07161 - - 0.00007076 54.0
HKD2_k127_9251893_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1073.0
HKD2_k127_9251893_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001027 274.0
HKD2_k127_9251893_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004847 280.0
HKD2_k127_9251893_3 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000004087 211.0
HKD2_k127_9251893_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000001687 211.0
HKD2_k127_9251893_5 - - - - 0.00000001288 66.0
HKD2_k127_9251893_6 Tetratricopeptide repeat - - - 0.00008272 52.0
HKD2_k127_9253355_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009676 306.0
HKD2_k127_9253355_1 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001503 294.0
HKD2_k127_9253355_10 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000004452 62.0
HKD2_k127_9253355_11 PFAM Nitrate reductase gamma subunit - - - 0.0001095 54.0
HKD2_k127_9253355_2 TonB dependent receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001176 293.0
HKD2_k127_9253355_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002817 247.0
HKD2_k127_9253355_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001543 256.0
HKD2_k127_9253355_5 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000168 214.0
HKD2_k127_9253355_6 Abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000003767 211.0
HKD2_k127_9253355_7 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.000000000000000000000000004492 123.0
HKD2_k127_9253355_8 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000003571 110.0
HKD2_k127_9253355_9 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.0000000000000000000006057 106.0
HKD2_k127_9304074_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.599e-298 935.0
HKD2_k127_9304074_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 377.0
HKD2_k127_9304074_10 Belongs to the UPF0434 family K09791 - - 0.000000000000004123 78.0
HKD2_k127_9304074_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.00000000000006122 83.0
HKD2_k127_9304074_12 Belongs to the HesB IscA family - - - 0.0000000000004479 70.0
HKD2_k127_9304074_13 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000002159 55.0
HKD2_k127_9304074_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 369.0
HKD2_k127_9304074_3 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001172 289.0
HKD2_k127_9304074_4 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000001958 269.0
HKD2_k127_9304074_5 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000006236 218.0
HKD2_k127_9304074_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000004919 221.0
HKD2_k127_9304074_7 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000006655 188.0
HKD2_k127_9304074_8 cheY-homologous receiver domain - - - 0.0000000000000000000000000000002465 126.0
HKD2_k127_9304074_9 O-antigen polymerase K18814 - - 0.0000000000000000000001531 111.0
HKD2_k127_9343381_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 607.0
HKD2_k127_9343381_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 603.0
HKD2_k127_9343381_10 indolepyruvate ferredoxin oxidoreductase beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000004666 187.0
HKD2_k127_9343381_11 Tetratricopeptide repeat-like domain - - - 0.0001071 54.0
HKD2_k127_9343381_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 452.0
HKD2_k127_9343381_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
HKD2_k127_9343381_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 370.0
HKD2_k127_9343381_5 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 290.0
HKD2_k127_9343381_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 268.0
HKD2_k127_9343381_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000001754 213.0
HKD2_k127_9343381_8 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000007461 203.0
HKD2_k127_9343381_9 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000164 194.0
HKD2_k127_9364961_0 Domains REC, sigma54 interaction, HTH8 - - - 3.172e-213 670.0
HKD2_k127_9364961_1 Cache domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 576.0
HKD2_k127_9364961_2 PFAM major facilitator superfamily MFS_1 K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 539.0
HKD2_k127_9364961_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 473.0
HKD2_k127_9364961_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 346.0
HKD2_k127_9364961_5 anaerobic respiration - - - 0.000000000000000000000000000000000000000000004351 182.0
HKD2_k127_9376733_0 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 455.0
HKD2_k127_9376733_1 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 359.0
HKD2_k127_9376733_2 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002369 269.0
HKD2_k127_9376733_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000001188 168.0
HKD2_k127_9376733_4 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000001811 72.0
HKD2_k127_9376733_5 Rubrerythrin - - - 0.00000008931 60.0
HKD2_k127_9536925_0 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 532.0
HKD2_k127_9536925_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000004468 252.0
HKD2_k127_9536925_2 LysM domain K01449,K19223 - 3.5.1.28 0.000000000000000000000000000000000000000000000000004105 201.0
HKD2_k127_9536925_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000001121 119.0
HKD2_k127_9536925_4 Helix-hairpin-helix motif K02237 - - 0.00000000000001563 77.0
HKD2_k127_9583939_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 269.0
HKD2_k127_9583939_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
HKD2_k127_9583939_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000005406 214.0
HKD2_k127_9583939_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000000000000007175 160.0
HKD2_k127_9583939_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000000000003032 158.0
HKD2_k127_9583939_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000041 141.0
HKD2_k127_9583939_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000001365 129.0
HKD2_k127_9629341_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 535.0
HKD2_k127_9629341_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000002039 173.0
HKD2_k127_9629341_2 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000002917 133.0
HKD2_k127_9663275_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 469.0
HKD2_k127_9663275_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 379.0
HKD2_k127_9663275_10 - - - - 0.00000000001096 68.0
HKD2_k127_9663275_11 Ribosomal protein L34 K02914 - - 0.00000000002669 65.0
HKD2_k127_9663275_2 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000001007 256.0
HKD2_k127_9663275_3 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000005032 238.0
HKD2_k127_9663275_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000001381 156.0
HKD2_k127_9663275_5 Yqey-like protein K09117 - - 0.00000000000000000000000000000000002914 143.0
HKD2_k127_9663275_6 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000006367 114.0
HKD2_k127_9663275_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000006174 104.0
HKD2_k127_9663275_8 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001488 87.0
HKD2_k127_9663275_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000002184 83.0
HKD2_k127_9792290_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1916.0
HKD2_k127_9792290_1 Fibronectin type 3 domain - - - 0.0 1043.0
HKD2_k127_9792290_10 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001369 233.0
HKD2_k127_9792290_11 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000001256 239.0
HKD2_k127_9792290_12 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000001977 209.0
HKD2_k127_9792290_13 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000000000000000000003078 199.0
HKD2_k127_9792290_14 NosL - - - 0.0000000000000000000000000000000000000000000000000000003681 200.0
HKD2_k127_9792290_15 PFAM LmbE family protein K01463 - - 0.00000000000000000000000000000000000000000000002951 179.0
HKD2_k127_9792290_16 metal-dependent phosphohydrolase HD - - - 0.000000000000000000000000000000000000000000008848 171.0
HKD2_k127_9792290_17 NosL - - - 0.00000000000000000000000000000000000000000005548 167.0
HKD2_k127_9792290_18 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000001847 157.0
HKD2_k127_9792290_19 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000001951 155.0
HKD2_k127_9792290_2 PFAM multicopper oxidase type 2 - - - 1.161e-308 968.0
HKD2_k127_9792290_20 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000001847 151.0
HKD2_k127_9792290_22 Ribosomal silencing factor during starvation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.00000000000000000000000000008279 122.0
HKD2_k127_9792290_23 PFAM Glutaredoxin K06191 - - 0.000000000000000000000000000136 117.0
HKD2_k127_9792290_24 DDE superfamily endonuclease - - - 0.0000000000000000000001279 106.0
HKD2_k127_9792290_25 - - - - 0.0000000000000000000003154 98.0
HKD2_k127_9792290_26 Predicted membrane protein (DUF2318) - - - 0.0000000000000001428 90.0
HKD2_k127_9792290_27 Belongs to the phosphoenolpyruvate carboxykinase (ATP) family K01610 - 4.1.1.49 0.0000000000002168 79.0
HKD2_k127_9792290_28 Heat shock 70 kDa protein K04043 - - 0.0001742 51.0
HKD2_k127_9792290_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 7.849e-289 900.0
HKD2_k127_9792290_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 506.0
HKD2_k127_9792290_5 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 423.0
HKD2_k127_9792290_6 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 379.0
HKD2_k127_9792290_7 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 310.0
HKD2_k127_9792290_8 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 298.0
HKD2_k127_9792290_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000553 288.0
HKD2_k127_9860015_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 338.0
HKD2_k127_9860015_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006065 281.0
HKD2_k127_9860015_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000004813 147.0
HKD2_k127_9860015_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000001998 99.0
HKD2_k127_9860015_4 Lysin motif - - - 0.0000000000001119 84.0
HKD2_k127_9860015_5 Protein of unknown function (DUF721) - - - 0.00000000002139 72.0