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Overview

ID MAG01803
Name HKD2_bin.51
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Myxococcota_A
Class UBA9160
Order UBA9160
Family PR03
Genus PR03
Species
Assembly information
Completeness (%) 89.24
Contamination (%) 3.42
GC content (%) 73.0
N50 (bp) 28,114
Genome size (bp) 4,006,479

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3388

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10003640_0 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 512.0
HKD2_k127_10003640_1 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 468.0
HKD2_k127_10003640_2 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 349.0
HKD2_k127_10003640_3 - - - - 0.00000000000000000000000000000000000000000000000000000001015 224.0
HKD2_k127_10003640_5 SnoaL-like domain - - - 0.00000000000000000000000002036 113.0
HKD2_k127_10011161_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 379.0
HKD2_k127_10011161_1 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000001037 265.0
HKD2_k127_10011161_2 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000001669 169.0
HKD2_k127_10071507_0 acetyl-CoA hydrolase K18288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 580.0
HKD2_k127_10071507_1 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 546.0
HKD2_k127_10071507_10 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 433.0
HKD2_k127_10071507_11 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 390.0
HKD2_k127_10071507_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 366.0
HKD2_k127_10071507_13 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 331.0
HKD2_k127_10071507_14 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 284.0
HKD2_k127_10071507_15 PFAM ABC transporter K01990,K01992,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000178 259.0
HKD2_k127_10071507_16 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564,K02804 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000007349 226.0
HKD2_k127_10071507_17 Haem-binding domain - - - 0.000000000000000000000000000000000000000000000000000000008017 201.0
HKD2_k127_10071507_18 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000001549 202.0
HKD2_k127_10071507_19 Abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000002786 199.0
HKD2_k127_10071507_2 Iron Permease K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 524.0
HKD2_k127_10071507_20 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000006292 202.0
HKD2_k127_10071507_21 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000007397 189.0
HKD2_k127_10071507_22 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000212 165.0
HKD2_k127_10071507_23 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000000000000000002313 154.0
HKD2_k127_10071507_24 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000004291 167.0
HKD2_k127_10071507_25 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.3 0.0000000000000000000000000000000000003679 144.0
HKD2_k127_10071507_26 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000435 144.0
HKD2_k127_10071507_27 Selenocysteine-specific translation elongation factor K03833 - - 0.00000000000000000000000000006936 123.0
HKD2_k127_10071507_28 Domain of unknown function (DUF1956) - - - 0.00000000000000000000000001212 118.0
HKD2_k127_10071507_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000000003999 118.0
HKD2_k127_10071507_3 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 539.0
HKD2_k127_10071507_30 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.00000000000000000000002737 115.0
HKD2_k127_10071507_31 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000001475 110.0
HKD2_k127_10071507_32 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000002511 56.0
HKD2_k127_10071507_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 499.0
HKD2_k127_10071507_5 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 477.0
HKD2_k127_10071507_6 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 467.0
HKD2_k127_10071507_7 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 466.0
HKD2_k127_10071507_8 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 449.0
HKD2_k127_10071507_9 PFAM cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 429.0
HKD2_k127_10104684_0 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 447.0
HKD2_k127_10104684_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 329.0
HKD2_k127_10104684_2 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000002271 248.0
HKD2_k127_10104684_3 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000002928 223.0
HKD2_k127_10104684_4 Oxygen tolerance - - - 0.000000000000005671 89.0
HKD2_k127_10104684_5 molybdenum cofactor guanylyltransferase activity K03752 - 2.7.7.77 0.00000000001446 78.0
HKD2_k127_10104684_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000001296 75.0
HKD2_k127_10104684_7 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 0.0000000001876 73.0
HKD2_k127_10104684_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000003356 51.0
HKD2_k127_1227076_0 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 6.503e-262 855.0
HKD2_k127_1227076_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 580.0
HKD2_k127_1227076_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 379.0
HKD2_k127_1227076_11 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 361.0
HKD2_k127_1227076_12 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 345.0
HKD2_k127_1227076_13 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 336.0
HKD2_k127_1227076_14 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 317.0
HKD2_k127_1227076_15 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 323.0
HKD2_k127_1227076_16 Glucose inhibited division protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000116 272.0
HKD2_k127_1227076_17 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000003075 239.0
HKD2_k127_1227076_18 Squalene phytoene synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000031 247.0
HKD2_k127_1227076_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002165 231.0
HKD2_k127_1227076_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 515.0
HKD2_k127_1227076_20 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000001153 237.0
HKD2_k127_1227076_21 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000006105 212.0
HKD2_k127_1227076_22 Protein-disulfide isomerase - - - 0.00000000000000000000000000000000000000000000000000000766 198.0
HKD2_k127_1227076_23 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000003658 183.0
HKD2_k127_1227076_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000009147 176.0
HKD2_k127_1227076_25 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.0000000000000000000000000000000000000000549 167.0
HKD2_k127_1227076_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000003479 169.0
HKD2_k127_1227076_27 arylsulfatase activity - - - 0.000000000000000000000000000000000000007157 166.0
HKD2_k127_1227076_28 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000257 138.0
HKD2_k127_1227076_29 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000009509 124.0
HKD2_k127_1227076_3 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 512.0
HKD2_k127_1227076_30 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000003299 107.0
HKD2_k127_1227076_31 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000005975 79.0
HKD2_k127_1227076_32 Domain of unknown function (DUF4388) - - - 0.000000000002549 80.0
HKD2_k127_1227076_33 Tetracycline transcriptional repressor MAATS-type K03577 - - 0.000000000005749 79.0
HKD2_k127_1227076_34 Protein conserved in bacteria K09986 - - 0.00000004907 63.0
HKD2_k127_1227076_35 PilZ domain - - - 0.000003537 58.0
HKD2_k127_1227076_4 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 491.0
HKD2_k127_1227076_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 426.0
HKD2_k127_1227076_6 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 432.0
HKD2_k127_1227076_7 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 404.0
HKD2_k127_1227076_8 TIGRFAM squalene-associated FAD-dependent desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 428.0
HKD2_k127_1227076_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015036,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0016667,GO:0016668,GO:0019725,GO:0019899,GO:0032991,GO:0035375,GO:0036094,GO:0040007,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0045454,GO:0048037,GO:0050660,GO:0050662,GO:0050789,GO:0050794,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0070404,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 409.0
HKD2_k127_128697_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 4.427e-242 774.0
HKD2_k127_128697_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.89e-225 707.0
HKD2_k127_128697_10 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 405.0
HKD2_k127_128697_11 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 382.0
HKD2_k127_128697_12 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 353.0
HKD2_k127_128697_13 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 313.0
HKD2_k127_128697_14 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 336.0
HKD2_k127_128697_15 Peptidase family C69 K14358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 304.0
HKD2_k127_128697_16 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002265 285.0
HKD2_k127_128697_17 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 294.0
HKD2_k127_128697_18 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 263.0
HKD2_k127_128697_19 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003838 280.0
HKD2_k127_128697_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 1.552e-209 691.0
HKD2_k127_128697_20 Transcriptional regulatory protein, C terminal K07665 GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010556,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0042221,GO:0042802,GO:0046688,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006294 261.0
HKD2_k127_128697_21 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000008578 232.0
HKD2_k127_128697_22 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000559 226.0
HKD2_k127_128697_23 - - - - 0.00000000000000000000000000000000000000000000000000000001921 213.0
HKD2_k127_128697_24 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000001088 176.0
HKD2_k127_128697_25 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000000000000000000000000002058 172.0
HKD2_k127_128697_26 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000003174 155.0
HKD2_k127_128697_27 Ring hydroxylating beta subunit - - - 0.00000000000000000000000000000000008598 154.0
HKD2_k127_128697_28 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000002952 136.0
HKD2_k127_128697_29 - - - - 0.00000000000000000000000000000008195 138.0
HKD2_k127_128697_3 Belongs to the RtcB family K14415 - 6.5.1.3 1.808e-194 629.0
HKD2_k127_128697_30 AhpC/TSA antioxidant enzyme - - - 0.000000000000000000001442 109.0
HKD2_k127_128697_31 - - - - 0.000000000000000000007573 98.0
HKD2_k127_128697_33 polyketide cyclase - - - 0.000000000000001154 83.0
HKD2_k127_128697_34 leucine-zipper of insertion element IS481 K07497 - - 0.00000000009795 73.0
HKD2_k127_128697_35 acid phosphatase K14379 - 3.1.3.2 0.0000000004287 71.0
HKD2_k127_128697_36 Archease protein family (MTH1598/TM1083) - - - 0.000000002224 71.0
HKD2_k127_128697_37 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000001187 58.0
HKD2_k127_128697_38 WHG domain - - - 0.000005463 53.0
HKD2_k127_128697_39 Belongs to the glycosyl hydrolase 18 family - - - 0.000006588 59.0
HKD2_k127_128697_4 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 632.0
HKD2_k127_128697_41 Helix-turn-helix domain - - - 0.00001543 53.0
HKD2_k127_128697_42 AhpC/TSA antioxidant enzyme - - - 0.00005159 46.0
HKD2_k127_128697_43 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001157 47.0
HKD2_k127_128697_44 Alpha beta - - - 0.0003525 44.0
HKD2_k127_128697_5 Pyridoxal-dependent decarboxylase conserved domain K01580,K01634 - 4.1.1.15,4.1.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 535.0
HKD2_k127_128697_6 FAD dependent oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 442.0
HKD2_k127_128697_7 synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 428.0
HKD2_k127_128697_8 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 408.0
HKD2_k127_128697_9 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 416.0
HKD2_k127_1302555_0 of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 390.0
HKD2_k127_1302555_1 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001695 290.0
HKD2_k127_1302555_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000003363 237.0
HKD2_k127_1302555_3 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001361 224.0
HKD2_k127_1302555_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000003594 205.0
HKD2_k127_1302555_5 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000003499 199.0
HKD2_k127_1302555_6 VIT family - - - 0.000000000000000000000000000000000000000000000004731 180.0
HKD2_k127_1302555_7 tRNA nucleotidyltransferase domain 2 putative K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000004562 181.0
HKD2_k127_1302555_8 Beta-lactamase - - - 0.000000000000000000000000000000001723 148.0
HKD2_k127_1338432_0 Domain of unknown function (DUF362) - - - 2.6e-209 672.0
HKD2_k127_1338432_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 378.0
HKD2_k127_1338432_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 350.0
HKD2_k127_1338432_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 306.0
HKD2_k127_1338432_4 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009215 306.0
HKD2_k127_1338432_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 269.0
HKD2_k127_1338432_6 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001155 276.0
HKD2_k127_1338432_7 DsbA oxidoreductase - - - 0.00000000000000002654 96.0
HKD2_k127_1338432_8 tRNA nucleotidyltransferase domain 2 putative K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000001399 79.0
HKD2_k127_1437926_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.477e-197 629.0
HKD2_k127_1437926_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 476.0
HKD2_k127_1437926_10 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000001872 93.0
HKD2_k127_1437926_11 Aminoglycoside phosphotransferase - - - 0.00000002003 67.0
HKD2_k127_1437926_2 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 400.0
HKD2_k127_1437926_3 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 314.0
HKD2_k127_1437926_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K15232 - 6.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 267.0
HKD2_k127_1437926_5 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001041 269.0
HKD2_k127_1437926_6 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000379 188.0
HKD2_k127_1437926_7 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000004824 171.0
HKD2_k127_1437926_8 MaoC like domain K14449 - 4.2.1.148 0.00000000000000000000000000000000000000008054 167.0
HKD2_k127_1437926_9 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000001791 138.0
HKD2_k127_1456353_0 Carboxyl transferase domain - - - 1.129e-207 685.0
HKD2_k127_1456353_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 472.0
HKD2_k127_1456353_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000003418 175.0
HKD2_k127_1456353_11 - - - - 0.0000000000000000000000003589 122.0
HKD2_k127_1456353_12 Transcription regulator MerR DNA binding K21902 - - 0.000000000000000000001502 99.0
HKD2_k127_1456353_13 Competence protein ComEA K02237 - - 0.0000001043 56.0
HKD2_k127_1456353_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 452.0
HKD2_k127_1456353_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 359.0
HKD2_k127_1456353_4 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 340.0
HKD2_k127_1456353_5 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 326.0
HKD2_k127_1456353_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 317.0
HKD2_k127_1456353_7 FAD dependent oxidoreductase K09471 - - 0.0000000000000000000000000000000000000000000000000000000000000000001995 248.0
HKD2_k127_1456353_8 PFAM ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000001491 244.0
HKD2_k127_1456353_9 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000005157 221.0
HKD2_k127_1529850_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000004289 191.0
HKD2_k127_1529850_1 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.000000000000000000000000000000000000000000005649 179.0
HKD2_k127_1529850_2 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000879 146.0
HKD2_k127_1529850_3 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000226 153.0
HKD2_k127_1529850_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000006486 129.0
HKD2_k127_1529850_5 Tyrosine phosphatase family - - - 0.000000000000000000001144 111.0
HKD2_k127_1529850_6 Dodecin K09165 - - 0.000000000000004977 82.0
HKD2_k127_1529850_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000002351 81.0
HKD2_k127_1529850_8 ubiE/COQ5 methyltransferase family - - - 0.00000000006054 76.0
HKD2_k127_1529850_9 Dodecin K09165 - - 0.000000001036 63.0
HKD2_k127_1561633_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.674e-307 980.0
HKD2_k127_1561633_1 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.0000000000000000000002352 102.0
HKD2_k127_1561633_2 - - - - 0.00000562 55.0
HKD2_k127_1654357_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.029e-221 697.0
HKD2_k127_1654357_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 593.0
HKD2_k127_1654357_10 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000009651 223.0
HKD2_k127_1654357_11 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000269 209.0
HKD2_k127_1654357_12 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000004626 201.0
HKD2_k127_1654357_13 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000003873 171.0
HKD2_k127_1654357_14 KR domain - - - 0.0000000000000000000000000000000000001517 162.0
HKD2_k127_1654357_15 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000003238 147.0
HKD2_k127_1654357_16 Bacterial regulatory proteins, tetR family K22107 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0042803,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000001396 124.0
HKD2_k127_1654357_17 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000009964 114.0
HKD2_k127_1654357_18 Protein of unknown function (DUF1329) - - - 0.0000000000000001391 93.0
HKD2_k127_1654357_2 epoxide hydrolase K01253 - 3.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 443.0
HKD2_k127_1654357_3 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 436.0
HKD2_k127_1654357_4 lipid-transfer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 433.0
HKD2_k127_1654357_5 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 379.0
HKD2_k127_1654357_6 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 384.0
HKD2_k127_1654357_7 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 346.0
HKD2_k127_1654357_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000353 250.0
HKD2_k127_1654357_9 Belongs to the BI1 family K06890,K19416 - - 0.000000000000000000000000000000000000000000000000000000000000004511 229.0
HKD2_k127_1676685_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 7.105e-208 677.0
HKD2_k127_1676685_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 477.0
HKD2_k127_1676685_10 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000005874 161.0
HKD2_k127_1676685_11 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000006256 97.0
HKD2_k127_1676685_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 405.0
HKD2_k127_1676685_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 400.0
HKD2_k127_1676685_4 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 334.0
HKD2_k127_1676685_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 323.0
HKD2_k127_1676685_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002088 285.0
HKD2_k127_1676685_7 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001392 245.0
HKD2_k127_1676685_8 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000009097 233.0
HKD2_k127_1676685_9 PFAM MOSC domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000001443 218.0
HKD2_k127_1683970_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 556.0
HKD2_k127_1683970_1 TIGRFAM hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 512.0
HKD2_k127_1683970_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 297.0
HKD2_k127_1683970_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002915 281.0
HKD2_k127_1683970_4 protein conserved in bacteria K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000553 273.0
HKD2_k127_1683970_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 258.0
HKD2_k127_1683970_6 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000006553 245.0
HKD2_k127_1683970_7 PFAM Acetyltransferase (GNAT) family K06976 - - 0.000000000000000000000000000000000000000000000000000000000000005034 246.0
HKD2_k127_1683970_8 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000006504 235.0
HKD2_k127_1683970_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000304 139.0
HKD2_k127_1692233_0 heat shock protein 70 K04043 - - 1.476e-203 649.0
HKD2_k127_1692233_1 GAD domain K01876 - 6.1.1.12 1.055e-197 634.0
HKD2_k127_1692233_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 339.0
HKD2_k127_1692233_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 316.0
HKD2_k127_1692233_12 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000832 276.0
HKD2_k127_1692233_13 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000003146 233.0
HKD2_k127_1692233_14 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000001349 211.0
HKD2_k127_1692233_15 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000002467 214.0
HKD2_k127_1692233_16 Cupin domain-containing protein - - - 0.0000000000000000000000000000000000002183 147.0
HKD2_k127_1692233_17 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00112 - 1.1.5.3 0.0000000000000000000000000000000009576 152.0
HKD2_k127_1692233_18 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000001512 113.0
HKD2_k127_1692233_19 DnaJ molecular chaperone homology domain - - - 0.0000000000000000005895 102.0
HKD2_k127_1692233_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 4.639e-196 619.0
HKD2_k127_1692233_20 response regulator K02667 - - 0.000000000000000001797 100.0
HKD2_k127_1692233_21 DNA protecting protein DprA K04096 - - 0.00000000005694 68.0
HKD2_k127_1692233_22 LysM domain - - - 0.00000003517 67.0
HKD2_k127_1692233_3 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 596.0
HKD2_k127_1692233_4 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 546.0
HKD2_k127_1692233_5 Glucose inhibited division protein A K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 479.0
HKD2_k127_1692233_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 476.0
HKD2_k127_1692233_7 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 454.0
HKD2_k127_1692233_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
HKD2_k127_1692233_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 406.0
HKD2_k127_1697604_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 505.0
HKD2_k127_1697604_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 356.0
HKD2_k127_1697604_2 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000004935 196.0
HKD2_k127_1697604_3 Major Facilitator Superfamily - - - 0.000000000000004903 87.0
HKD2_k127_1697604_4 Phosphoesterase K07095 - - 0.000000001222 59.0
HKD2_k127_1714384_0 PAS domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 603.0
HKD2_k127_1714384_1 response regulator K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 537.0
HKD2_k127_1714384_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 411.0
HKD2_k127_1714384_3 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 347.0
HKD2_k127_1714384_4 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000009648 202.0
HKD2_k127_1714384_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000008948 114.0
HKD2_k127_1714384_6 FR47-like protein K03789 - 2.3.1.128 0.00000000000000002242 89.0
HKD2_k127_1714384_7 belongs to the thioredoxin family K03619,K05838 - - 0.000006563 59.0
HKD2_k127_177721_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 325.0
HKD2_k127_177721_1 Sterol-sensing domain of SREBP cleavage-activation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003511 278.0
HKD2_k127_177721_10 Bacterial SH3 domain homologues K07184 - - 0.000000002587 70.0
HKD2_k127_177721_2 Two component transcriptional regulator, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004647 257.0
HKD2_k127_177721_3 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001443 260.0
HKD2_k127_177721_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000004271 179.0
HKD2_k127_177721_5 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000003897 149.0
HKD2_k127_177721_6 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.000000000000000000000000000000009574 136.0
HKD2_k127_177721_7 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000381 104.0
HKD2_k127_177721_8 CAAX protease self-immunity K07052 - - 0.0000000000000000009276 95.0
HKD2_k127_177721_9 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.00000000000001044 83.0
HKD2_k127_177956_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.0 1317.0
HKD2_k127_177956_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.824e-275 883.0
HKD2_k127_177956_10 Secretory lipase - - - 0.0000000000000000000000000000000000000000000000000000000001045 221.0
HKD2_k127_177956_11 Acetyltransferase (GNAT) domain K22479 - - 0.0000000000000000000000000000000000000000000000000000000001273 218.0
HKD2_k127_177956_12 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000001586 221.0
HKD2_k127_177956_13 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000001797 226.0
HKD2_k127_177956_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000001927 191.0
HKD2_k127_177956_15 luxR family - - - 0.00000000000000000000000000000000000002443 150.0
HKD2_k127_177956_16 transcriptional regulator - - - 0.00000000000000000000000000000000004869 144.0
HKD2_k127_177956_17 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000001173 110.0
HKD2_k127_177956_18 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.000000000000000000007163 98.0
HKD2_k127_177956_19 - - - - 0.0000000000000000003421 101.0
HKD2_k127_177956_2 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 529.0
HKD2_k127_177956_20 Outer membrane lipoprotein-sorting protein - - - 0.00004786 56.0
HKD2_k127_177956_21 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00005106 55.0
HKD2_k127_177956_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 498.0
HKD2_k127_177956_4 cytochrome p450 K17474 - 1.14.15.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 417.0
HKD2_k127_177956_5 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 371.0
HKD2_k127_177956_6 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
HKD2_k127_177956_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 332.0
HKD2_k127_177956_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 312.0
HKD2_k127_177956_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000009347 234.0
HKD2_k127_181210_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1177.0
HKD2_k127_181210_1 6-phosphogluconolactonase activity - - - 0.0 1068.0
HKD2_k127_181210_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000001405 89.0
HKD2_k127_181210_11 transcriptional - - - 0.000000000000001653 87.0
HKD2_k127_181210_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000001691 85.0
HKD2_k127_181210_13 Thermolysin metallopeptidase, catalytic domain K01400 - 3.4.24.28 0.0000000000001339 81.0
HKD2_k127_181210_14 F420H(2)-dependent quinone reductase - - - 0.000002413 56.0
HKD2_k127_181210_15 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.0004604 43.0
HKD2_k127_181210_16 - - - - 0.0006369 52.0
HKD2_k127_181210_2 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 537.0
HKD2_k127_181210_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 325.0
HKD2_k127_181210_4 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 329.0
HKD2_k127_181210_5 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002259 250.0
HKD2_k127_181210_6 COG1145 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000001043 230.0
HKD2_k127_181210_7 glycosyl transferase family 39 K00721 - 2.4.1.83 0.0000000000000000000000000000000000003157 161.0
HKD2_k127_181210_8 Domain of unknown function (DUF4870) K09940 - - 0.000000000000000000000005928 105.0
HKD2_k127_181210_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000006573 105.0
HKD2_k127_1884001_0 Dehydrogenase K00114,K17760,K22473 - 1.1.2.8,1.1.5.5,1.1.9.1 2.695e-246 779.0
HKD2_k127_1884001_1 DEAD DEAH box K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 561.0
HKD2_k127_1884001_10 GAF domain - - - 0.00000000000000000000000000000000000000000000001645 183.0
HKD2_k127_1884001_11 Limonene-1,2-epoxide hydrolase catalytic domain K10533 - 3.3.2.8 0.0000000000000000000000000000000000000000000001627 177.0
HKD2_k127_1884001_12 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000002035 171.0
HKD2_k127_1884001_13 - - - - 0.0000000000000000000000000000000004634 136.0
HKD2_k127_1884001_14 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000009631 134.0
HKD2_k127_1884001_15 sirohydrochlorin cobaltochelatase activity K03794 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009058,GO:0009507,GO:0009536,GO:0009987,GO:0016829,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046156,GO:0046483,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051266,GO:0051536,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.4 0.00000000000000000000001521 108.0
HKD2_k127_1884001_16 Protein of unknown function (DUF2834) - - - 0.00000000000001178 85.0
HKD2_k127_1884001_17 Choline/ethanolamine kinase - - - 0.00000000000006639 86.0
HKD2_k127_1884001_19 alpha-ribazole phosphatase activity K00768,K15634 - 2.4.2.21,5.4.2.12 0.000000002799 70.0
HKD2_k127_1884001_2 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 508.0
HKD2_k127_1884001_20 - - - - 0.000000005623 68.0
HKD2_k127_1884001_21 PFAM ferredoxin - - - 0.00000245 56.0
HKD2_k127_1884001_22 Cytochrome C biogenesis K02200 - - 0.00001391 55.0
HKD2_k127_1884001_23 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00001669 57.0
HKD2_k127_1884001_25 SNARE associated Golgi protein - - - 0.000165 56.0
HKD2_k127_1884001_3 response regulator K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007873 413.0
HKD2_k127_1884001_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
HKD2_k127_1884001_5 Belongs to the TPP enzyme family K01568,K04103 - 4.1.1.1,4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 340.0
HKD2_k127_1884001_6 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003039 273.0
HKD2_k127_1884001_7 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000008419 228.0
HKD2_k127_1884001_8 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000002976 227.0
HKD2_k127_1884001_9 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000000000000003774 207.0
HKD2_k127_195563_0 Aldehyde dehydrogenase K04072,K15515 - 1.1.1.1,1.2.1.10,1.2.1.81 0.0 1123.0
HKD2_k127_195563_1 Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine K00821,K09251 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575 2.6.1.11,2.6.1.17,2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 469.0
HKD2_k127_195563_2 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 462.0
HKD2_k127_195563_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 370.0
HKD2_k127_195563_4 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 327.0
HKD2_k127_195563_5 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 317.0
HKD2_k127_195563_6 PFAM aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008148 263.0
HKD2_k127_195563_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000002389 184.0
HKD2_k127_195563_8 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000004786 179.0
HKD2_k127_195563_9 - - - - 0.00001542 54.0
HKD2_k127_201489_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 1.157e-301 929.0
HKD2_k127_201489_1 amidohydrolase - - - 6.751e-216 683.0
HKD2_k127_201489_10 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 402.0
HKD2_k127_201489_11 PFAM Acyl-CoA dehydrogenase, type 2, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 391.0
HKD2_k127_201489_12 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 364.0
HKD2_k127_201489_13 Amidohydrolase K22213 - 4.1.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 347.0
HKD2_k127_201489_14 PFAM Glyoxalase bleomycin resistance protein dioxygenase K11945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 333.0
HKD2_k127_201489_15 Homocysteine S-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 305.0
HKD2_k127_201489_16 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 309.0
HKD2_k127_201489_17 hydratase K01617,K02554 - 4.1.1.77,4.2.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001003 279.0
HKD2_k127_201489_18 Alpha beta hydrolase K10216 - 3.7.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000006917 275.0
HKD2_k127_201489_19 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001467 262.0
HKD2_k127_201489_2 Pyridine nucleotide-disulphide oxidoreductase - - - 7.718e-212 677.0
HKD2_k127_201489_20 tetR family - - - 0.000000000000000000000000000000000000000000000009065 185.0
HKD2_k127_201489_21 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000004013 169.0
HKD2_k127_201489_22 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000001091 154.0
HKD2_k127_201489_23 GAF domain - - - 0.0000000000000000000000000000000002021 154.0
HKD2_k127_201489_24 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000001888 131.0
HKD2_k127_201489_25 endoribonuclease L-PSP - - - 0.0000000000000000000001236 111.0
HKD2_k127_201489_26 - - - - 0.0000000000000005027 92.0
HKD2_k127_201489_27 - - - - 0.000000000001365 70.0
HKD2_k127_201489_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 538.0
HKD2_k127_201489_4 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 505.0
HKD2_k127_201489_5 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 502.0
HKD2_k127_201489_6 DAHP synthetase I family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 492.0
HKD2_k127_201489_7 DmpG-like communication domain K01666 - 4.1.3.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 468.0
HKD2_k127_201489_8 sulfuric ester hydrolase activity K07014 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 467.0
HKD2_k127_201489_9 Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds K04073 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008774,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 422.0
HKD2_k127_2015538_0 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000009297 168.0
HKD2_k127_2015538_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000524 152.0
HKD2_k127_2015538_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000002428 83.0
HKD2_k127_2015538_3 membrane protein, required for N-linked glycosylation K07151 - 2.4.99.18 0.0006036 52.0
HKD2_k127_2023680_0 Amidohydrolase family - - - 3.334e-228 720.0
HKD2_k127_2023680_1 dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 526.0
HKD2_k127_2023680_10 PaaX-like protein C-terminal domain K02616 - - 0.000000000000000000000000000000000000000001333 167.0
HKD2_k127_2023680_11 Transcriptional regulator - - - 0.0000000000000000000000000000000000001401 149.0
HKD2_k127_2023680_12 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000006961 72.0
HKD2_k127_2023680_13 PPIC-type PPIASE domain - - - 0.000000000002358 81.0
HKD2_k127_2023680_14 - - - - 0.0000002529 61.0
HKD2_k127_2023680_15 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0008684 44.0
HKD2_k127_2023680_2 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 463.0
HKD2_k127_2023680_3 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 443.0
HKD2_k127_2023680_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 372.0
HKD2_k127_2023680_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
HKD2_k127_2023680_6 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005943 270.0
HKD2_k127_2023680_7 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003324 255.0
HKD2_k127_2023680_8 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000007898 241.0
HKD2_k127_2023680_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000006843 162.0
HKD2_k127_2026757_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 550.0
HKD2_k127_2026757_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928,K03587,K15792 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 3.4.16.4,6.3.2.10,6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 419.0
HKD2_k127_2026757_10 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001721 276.0
HKD2_k127_2026757_11 ATP cone domain K05715 - - 0.000000000000000000000000000000000000000000000000000000000000000004919 240.0
HKD2_k127_2026757_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000002108 237.0
HKD2_k127_2026757_13 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000005363 222.0
HKD2_k127_2026757_14 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000001568 207.0
HKD2_k127_2026757_15 translation initiation factor activity K03496,K09000 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000003358 194.0
HKD2_k127_2026757_16 thiolester hydrolase activity K06889 - - 0.000000000000000000000000844 113.0
HKD2_k127_2026757_17 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000002892 108.0
HKD2_k127_2026757_18 DNA-templated transcription, initiation K03088 - - 0.000000000000000000007964 101.0
HKD2_k127_2026757_19 PHB/PHA accumulation regulator DNA-binding domain - - - 0.0000000000000000002619 102.0
HKD2_k127_2026757_2 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 422.0
HKD2_k127_2026757_20 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000001139 85.0
HKD2_k127_2026757_21 signal peptide peptidase K04773 - - 0.0000000000000009057 93.0
HKD2_k127_2026757_22 Tetratricopeptide repeat - - - 0.00000000000002418 80.0
HKD2_k127_2026757_23 TIGRFAM MJ0042 family finger-like protein - - - 0.0000001911 64.0
HKD2_k127_2026757_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 410.0
HKD2_k127_2026757_4 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 384.0
HKD2_k127_2026757_5 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 331.0
HKD2_k127_2026757_6 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 295.0
HKD2_k127_2026757_7 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 298.0
HKD2_k127_2026757_8 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000014 310.0
HKD2_k127_2026757_9 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002185 286.0
HKD2_k127_2162203_0 Flavoprotein involved in K transport K03379 - 1.14.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 597.0
HKD2_k127_2162203_1 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 400.0
HKD2_k127_2162203_2 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008389 295.0
HKD2_k127_2162203_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
HKD2_k127_2162203_4 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000626 232.0
HKD2_k127_2162203_5 - - - - 0.000000000000000000000000000000000000000000002745 187.0
HKD2_k127_2162203_6 Domain of unknown function (DUF4399) - - - 0.000000000000000000000000000000000000002094 161.0
HKD2_k127_2162203_7 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000222 152.0
HKD2_k127_218712_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1123.0
HKD2_k127_218712_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 416.0
HKD2_k127_218712_10 ig-like, plexins, transcription factors - - - 0.000000000000000003616 97.0
HKD2_k127_218712_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 366.0
HKD2_k127_218712_3 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 351.0
HKD2_k127_218712_4 Trypsin K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 354.0
HKD2_k127_218712_5 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000601 275.0
HKD2_k127_218712_6 ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000003271 251.0
HKD2_k127_218712_7 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000002677 175.0
HKD2_k127_218712_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000001811 145.0
HKD2_k127_218712_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000001936 139.0
HKD2_k127_2205301_0 Alpha-2-Macroglobulin K06894 - - 0.0 1538.0
HKD2_k127_2205301_1 Sulfatase K01130 - 3.1.6.1 0.0 1357.0
HKD2_k127_2205301_10 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K08321,K11645 - 2.3.1.245,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 438.0
HKD2_k127_2205301_11 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 465.0
HKD2_k127_2205301_12 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 422.0
HKD2_k127_2205301_13 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 381.0
HKD2_k127_2205301_14 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 377.0
HKD2_k127_2205301_15 Na dependent nucleoside transporter K03317 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 337.0
HKD2_k127_2205301_16 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 353.0
HKD2_k127_2205301_17 Potential Queuosine, Q, salvage protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 317.0
HKD2_k127_2205301_18 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 310.0
HKD2_k127_2205301_19 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003251 284.0
HKD2_k127_2205301_2 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 4.35e-205 665.0
HKD2_k127_2205301_20 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006611 286.0
HKD2_k127_2205301_21 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001272 286.0
HKD2_k127_2205301_22 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000006239 258.0
HKD2_k127_2205301_23 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008813 253.0
HKD2_k127_2205301_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004737 243.0
HKD2_k127_2205301_25 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000025 240.0
HKD2_k127_2205301_26 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000007097 214.0
HKD2_k127_2205301_27 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000001087 205.0
HKD2_k127_2205301_28 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000169 216.0
HKD2_k127_2205301_29 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000007918 198.0
HKD2_k127_2205301_3 Short chain dehydrogenase - - - 2.644e-197 638.0
HKD2_k127_2205301_30 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000002421 180.0
HKD2_k127_2205301_31 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000001506 191.0
HKD2_k127_2205301_32 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000000000000000000001221 166.0
HKD2_k127_2205301_33 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000001069 175.0
HKD2_k127_2205301_34 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000008928 166.0
HKD2_k127_2205301_35 COG2853 Surface lipoprotein K04754 - - 0.0000000000000000000000000000000000000002291 168.0
HKD2_k127_2205301_36 PHP domain protein - - - 0.000000000000000000000000000000000000005878 168.0
HKD2_k127_2205301_37 penicillin-binding protein - - - 0.0000000000000000000000000000000000002665 159.0
HKD2_k127_2205301_38 PFAM ABC transporter K06857 - 3.6.3.55 0.000000000000000000000000000000000005754 156.0
HKD2_k127_2205301_39 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000004865 137.0
HKD2_k127_2205301_4 Carboxyl transferase domain - - - 3.381e-196 634.0
HKD2_k127_2205301_40 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000001443 143.0
HKD2_k127_2205301_41 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000003327 145.0
HKD2_k127_2205301_42 MlaC protein K07323 - - 0.0000000000000000000000000000001478 142.0
HKD2_k127_2205301_43 - - - - 0.0000000000000000000000000008825 117.0
HKD2_k127_2205301_44 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000001293 111.0
HKD2_k127_2205301_45 Belongs to the Fur family K09825 - - 0.0000000000000000000000001702 111.0
HKD2_k127_2205301_46 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000005111 104.0
HKD2_k127_2205301_47 Predicted permease K07089 - - 0.00000000000000000001259 107.0
HKD2_k127_2205301_48 FCD K05799 - - 0.0000000000000006139 87.0
HKD2_k127_2205301_49 phosphoglycolate phosphatase activity - - - 0.00000000000002416 83.0
HKD2_k127_2205301_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K18688 - 6.2.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 595.0
HKD2_k127_2205301_50 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.000000000001086 70.0
HKD2_k127_2205301_51 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000001171 78.0
HKD2_k127_2205301_52 Cold shock protein K03704 - - 0.0000000002611 69.0
HKD2_k127_2205301_53 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000002097 67.0
HKD2_k127_2205301_54 PFAM Abortive infection protein K07052 - - 0.00000000933 66.0
HKD2_k127_2205301_55 ThiS family K03636 - - 0.00000003653 58.0
HKD2_k127_2205301_56 - - - - 0.000001035 58.0
HKD2_k127_2205301_57 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00005869 48.0
HKD2_k127_2205301_6 penicillin-binding protein K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 589.0
HKD2_k127_2205301_7 'Molybdopterin K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 456.0
HKD2_k127_2205301_8 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 470.0
HKD2_k127_2205301_9 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 458.0
HKD2_k127_2216278_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1458.0
HKD2_k127_2216278_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.307e-242 787.0
HKD2_k127_2216278_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 304.0
HKD2_k127_2216278_11 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 302.0
HKD2_k127_2216278_12 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 299.0
HKD2_k127_2216278_13 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
HKD2_k127_2216278_14 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000276 233.0
HKD2_k127_2216278_15 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000006801 213.0
HKD2_k127_2216278_16 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004476 218.0
HKD2_k127_2216278_17 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000008327 203.0
HKD2_k127_2216278_18 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004755 200.0
HKD2_k127_2216278_19 Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000003922 193.0
HKD2_k127_2216278_2 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 514.0
HKD2_k127_2216278_20 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000002262 204.0
HKD2_k127_2216278_21 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004584 193.0
HKD2_k127_2216278_22 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002754 181.0
HKD2_k127_2216278_23 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000174 181.0
HKD2_k127_2216278_24 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001883 194.0
HKD2_k127_2216278_25 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000008978 190.0
HKD2_k127_2216278_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000002126 153.0
HKD2_k127_2216278_27 Glutathione peroxidase - - - 0.00000000000000000000000000000000001236 144.0
HKD2_k127_2216278_28 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001681 153.0
HKD2_k127_2216278_29 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000002475 133.0
HKD2_k127_2216278_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 501.0
HKD2_k127_2216278_30 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000003089 124.0
HKD2_k127_2216278_31 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000002628 117.0
HKD2_k127_2216278_32 Ribosomal protein L22p/L17e K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000003535 111.0
HKD2_k127_2216278_33 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000004602 116.0
HKD2_k127_2216278_34 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001011 103.0
HKD2_k127_2216278_35 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001084 79.0
HKD2_k127_2216278_36 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000002342 75.0
HKD2_k127_2216278_37 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000000000004052 74.0
HKD2_k127_2216278_38 Ribosomal protein L30 K02907 - - 0.00000000001335 74.0
HKD2_k127_2216278_39 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000002111 68.0
HKD2_k127_2216278_4 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 492.0
HKD2_k127_2216278_40 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000004642 64.0
HKD2_k127_2216278_41 PFAM Sporulation domain protein K03749 - - 0.000006768 59.0
HKD2_k127_2216278_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 481.0
HKD2_k127_2216278_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 434.0
HKD2_k127_2216278_7 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 446.0
HKD2_k127_2216278_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 396.0
HKD2_k127_2216278_9 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 360.0
HKD2_k127_2261008_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 590.0
HKD2_k127_2261008_1 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 546.0
HKD2_k127_2261008_10 Protein of unknown function (DUF3419) K13622 - - 0.00000000000000000000000000000000768 147.0
HKD2_k127_2261008_11 Rdx family K07401 - - 0.0000000000000000000000000004356 133.0
HKD2_k127_2261008_12 Involved in the tonB-independent uptake of proteins K01406,K03641,K21449 - 3.4.24.40 0.000000000000000000000001774 118.0
HKD2_k127_2261008_13 ECF sigma factor K03088 - - 0.0000000000000000000003773 105.0
HKD2_k127_2261008_14 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000009963 111.0
HKD2_k127_2261008_15 - - - - 0.000000000000002652 83.0
HKD2_k127_2261008_16 Outer membrane lipoprotein-sorting protein - - - 0.000000004085 70.0
HKD2_k127_2261008_17 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein K06006 - - 0.0006904 51.0
HKD2_k127_2261008_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 481.0
HKD2_k127_2261008_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 455.0
HKD2_k127_2261008_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 338.0
HKD2_k127_2261008_5 Acyl-CoA dehydrogenase, N-terminal domain K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006398 286.0
HKD2_k127_2261008_6 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005041 290.0
HKD2_k127_2261008_7 Glycine-zipper domain - - - 0.0000000000000000000000000000000000009704 152.0
HKD2_k127_2261008_8 PAS domain - - - 0.00000000000000000000000000000000001685 150.0
HKD2_k127_2261008_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000003916 140.0
HKD2_k127_2341196_0 CoA binding domain - - - 1.046e-251 796.0
HKD2_k127_2341196_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 2.764e-238 779.0
HKD2_k127_2341196_10 Domains Cache_1, HAMP, PAS, PAS K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000001343 221.0
HKD2_k127_2341196_11 transferase activity, transferring acyl groups K03824 - - 0.000000000000000000000000000000000000000000000000009246 185.0
HKD2_k127_2341196_12 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000006077 186.0
HKD2_k127_2341196_13 - - - - 0.000000000000000000000000000000000000000000007654 165.0
HKD2_k127_2341196_14 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000003917 126.0
HKD2_k127_2341196_15 zinc-ribbon domain - - - 0.00000000000006286 85.0
HKD2_k127_2341196_16 PFAM GGDEF domain containing protein - - - 0.0000000000001048 86.0
HKD2_k127_2341196_17 - - - - 0.0000000000002749 73.0
HKD2_k127_2341196_18 PFAM Sodium calcium exchanger membrane region K07301 - - 0.00000000003279 74.0
HKD2_k127_2341196_19 PFAM Forkhead-associated protein - - - 0.0000000001619 74.0
HKD2_k127_2341196_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.294e-199 643.0
HKD2_k127_2341196_20 - - - - 0.0006518 52.0
HKD2_k127_2341196_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 604.0
HKD2_k127_2341196_4 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 618.0
HKD2_k127_2341196_5 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 569.0
HKD2_k127_2341196_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 542.0
HKD2_k127_2341196_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 347.0
HKD2_k127_2341196_8 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 299.0
HKD2_k127_2341196_9 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008022 291.0
HKD2_k127_2367049_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 490.0
HKD2_k127_2367049_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 413.0
HKD2_k127_2367049_10 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000009233 178.0
HKD2_k127_2367049_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000003097 188.0
HKD2_k127_2367049_12 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000004987 173.0
HKD2_k127_2367049_13 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000008196 136.0
HKD2_k127_2367049_14 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000001391 120.0
HKD2_k127_2367049_15 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000006478 101.0
HKD2_k127_2367049_16 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000001561 108.0
HKD2_k127_2367049_17 Polymer-forming cytoskeletal - - - 0.0000000000000000000206 105.0
HKD2_k127_2367049_18 Peptidase MA superfamily - - - 0.000000000000000002372 100.0
HKD2_k127_2367049_19 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000001227 93.0
HKD2_k127_2367049_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 347.0
HKD2_k127_2367049_20 Cytochrome c class I - - - 0.00000000001397 78.0
HKD2_k127_2367049_21 NifU-like domain - - - 0.0000000000363 74.0
HKD2_k127_2367049_22 TonB family K03646,K03832 - - 0.000001483 60.0
HKD2_k127_2367049_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 310.0
HKD2_k127_2367049_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 304.0
HKD2_k127_2367049_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 306.0
HKD2_k127_2367049_6 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003757 274.0
HKD2_k127_2367049_7 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000001806 207.0
HKD2_k127_2367049_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000001257 207.0
HKD2_k127_2367049_9 Molybdopterin converting factor subunit K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000005661 191.0
HKD2_k127_2557035_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00122 - 1.17.1.9 7.438e-290 908.0
HKD2_k127_2557035_1 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.513e-241 755.0
HKD2_k127_2557035_10 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 451.0
HKD2_k127_2557035_11 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 425.0
HKD2_k127_2557035_12 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 427.0
HKD2_k127_2557035_13 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 385.0
HKD2_k127_2557035_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 379.0
HKD2_k127_2557035_15 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 360.0
HKD2_k127_2557035_16 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 329.0
HKD2_k127_2557035_17 Peptidase family M20/M25/M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 319.0
HKD2_k127_2557035_18 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 324.0
HKD2_k127_2557035_19 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001829 286.0
HKD2_k127_2557035_2 glutamine synthetase K01915 - 6.3.1.2 9.594e-212 668.0
HKD2_k127_2557035_20 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002314 286.0
HKD2_k127_2557035_21 Belongs to the heme-copper respiratory oxidase family K15862 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000002498 263.0
HKD2_k127_2557035_22 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004085 244.0
HKD2_k127_2557035_23 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000001293 239.0
HKD2_k127_2557035_24 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000002244 212.0
HKD2_k127_2557035_25 Protein conserved in bacteria K07028 - - 0.00000000000000000000000000000000000000000000000000000003158 224.0
HKD2_k127_2557035_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000003706 197.0
HKD2_k127_2557035_27 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000001042 188.0
HKD2_k127_2557035_28 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000005343 185.0
HKD2_k127_2557035_29 Inosine-uridine preferring nucleoside hydrolase K01239 - 3.2.2.1 0.0000000000000000000000000000000000000001316 169.0
HKD2_k127_2557035_3 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404,K00405,K15862 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 2.251e-198 632.0
HKD2_k127_2557035_30 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000681 160.0
HKD2_k127_2557035_31 Domains Cache_1, HAMP, PAS, PAS K02482 - 2.7.13.3 0.00000000000000000000000000000000001144 150.0
HKD2_k127_2557035_32 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000005856 136.0
HKD2_k127_2557035_33 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000001157 139.0
HKD2_k127_2557035_34 Conserved Protein - - - 0.000000000000000000000000009765 117.0
HKD2_k127_2557035_35 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000203 115.0
HKD2_k127_2557035_36 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.00000000000000000000007879 112.0
HKD2_k127_2557035_37 Biotin-requiring enzyme - - - 0.0000000000000000000006842 111.0
HKD2_k127_2557035_38 response regulator receiver - - - 0.0000000000000000003522 101.0
HKD2_k127_2557035_39 - - - - 0.00000000000000001186 98.0
HKD2_k127_2557035_4 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 585.0
HKD2_k127_2557035_40 Peptidase family M23 - - - 0.0000000000000006622 92.0
HKD2_k127_2557035_41 Sigma-54 interaction domain - - - 0.00000000000002968 87.0
HKD2_k127_2557035_42 CBS domain - - - 0.00000000000004922 86.0
HKD2_k127_2557035_43 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000004666 72.0
HKD2_k127_2557035_44 CBS domain K04767,K07168 - - 0.00000000002665 77.0
HKD2_k127_2557035_45 PFAM CBS domain containing protein K07168 - - 0.00000000005935 70.0
HKD2_k127_2557035_46 Acetyltransferase (GNAT) domain - - - 0.000000009488 68.0
HKD2_k127_2557035_47 His Kinase A (phosphoacceptor) domain - - - 0.00000007171 66.0
HKD2_k127_2557035_49 FixH - - - 0.000314 51.0
HKD2_k127_2557035_5 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 563.0
HKD2_k127_2557035_6 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 555.0
HKD2_k127_2557035_7 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 499.0
HKD2_k127_2557035_8 argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 481.0
HKD2_k127_2557035_9 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 475.0
HKD2_k127_2602549_0 PQQ enzyme repeat K17760 - 1.1.9.1 8.433e-254 808.0
HKD2_k127_2602549_1 Protein of unknown function (DUF3604) - - - 9.945e-237 757.0
HKD2_k127_2602549_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 392.0
HKD2_k127_2602549_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627 GO:0003674,GO:0003824,GO:0004742,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016407,GO:0016417,GO:0016418,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030523,GO:0031405,GO:0031406,GO:0032787,GO:0032991,GO:0033293,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1902494,GO:1990204 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003433 284.0
HKD2_k127_2602549_12 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000008361 222.0
HKD2_k127_2602549_13 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000001076 229.0
HKD2_k127_2602549_14 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000001224 209.0
HKD2_k127_2602549_15 Fusaric acid resistance protein-like - - - 0.00000000000000000000000000000000000000000000001457 179.0
HKD2_k127_2602549_16 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000001862 170.0
HKD2_k127_2602549_17 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000009925 134.0
HKD2_k127_2602549_18 ABC transporter substrate-binding protein K02067 - - 0.000000000000000000000000001238 127.0
HKD2_k127_2602549_19 PFAM toluene tolerance family protein K07323 - - 0.000000000000000000000226 107.0
HKD2_k127_2602549_2 amino acid K03294 - - 2.481e-196 623.0
HKD2_k127_2602549_20 alpha beta - - - 0.000000000000000000001428 109.0
HKD2_k127_2602549_21 radical SAM domain protein - - - 0.00000000000001196 89.0
HKD2_k127_2602549_22 periplasmic protein - - - 0.0000000000002063 85.0
HKD2_k127_2602549_23 - - - - 0.000001622 59.0
HKD2_k127_2602549_3 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 574.0
HKD2_k127_2602549_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 538.0
HKD2_k127_2602549_5 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 533.0
HKD2_k127_2602549_6 PFAM 2-nitropropane dioxygenase NPD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 506.0
HKD2_k127_2602549_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 498.0
HKD2_k127_2602549_8 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 489.0
HKD2_k127_2602549_9 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 436.0
HKD2_k127_2662321_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1282.0
HKD2_k127_2662321_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 9.085e-235 753.0
HKD2_k127_2662321_10 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 388.0
HKD2_k127_2662321_11 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 368.0
HKD2_k127_2662321_12 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 355.0
HKD2_k127_2662321_13 PFAM Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 346.0
HKD2_k127_2662321_14 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 313.0
HKD2_k127_2662321_15 HPP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001504 283.0
HKD2_k127_2662321_16 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002782 269.0
HKD2_k127_2662321_17 Protein of unknown function (DUF4243) - - - 0.000000000000000000000000000000000000000000000000000000000000000006785 244.0
HKD2_k127_2662321_18 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000008451 211.0
HKD2_k127_2662321_19 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000004172 216.0
HKD2_k127_2662321_2 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 534.0
HKD2_k127_2662321_20 methyltransferase K05928 - 2.1.1.95 0.0000000000000000000000000000000000000000000000004523 195.0
HKD2_k127_2662321_21 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000001395 195.0
HKD2_k127_2662321_22 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000487 173.0
HKD2_k127_2662321_23 SnoaL-like domain - - - 0.00000000000000000000000000000000000000001625 159.0
HKD2_k127_2662321_24 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000001872 150.0
HKD2_k127_2662321_25 AAA ATPase domain - - - 0.00000000000000000002229 104.0
HKD2_k127_2662321_26 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000004185 105.0
HKD2_k127_2662321_27 Methyltransferase domain - - - 0.0000000000000000001118 104.0
HKD2_k127_2662321_28 Glyoxalase-like domain - - - 0.0000000000000000004558 102.0
HKD2_k127_2662321_29 Bacterial regulatory proteins, tetR family - - - 0.000000000001728 79.0
HKD2_k127_2662321_3 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 552.0
HKD2_k127_2662321_30 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000385 65.0
HKD2_k127_2662321_31 DinB superfamily - - - 0.00000001916 67.0
HKD2_k127_2662321_32 Flavin and coenzyme A sequestration protein dodecin K09165 - - 0.0004443 53.0
HKD2_k127_2662321_4 GMP synthase (glutamine-hydrolyzing) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 548.0
HKD2_k127_2662321_5 NADH:flavin oxidoreductase / NADH oxidase family K22347 - 1.8.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 484.0
HKD2_k127_2662321_6 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 471.0
HKD2_k127_2662321_7 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 409.0
HKD2_k127_2662321_8 PFAM Amidohydrolase 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 405.0
HKD2_k127_2662321_9 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 386.0
HKD2_k127_2663393_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 614.0
HKD2_k127_2663393_1 PQQ-like domain K00117 - 1.1.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 635.0
HKD2_k127_2663393_10 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000008561 132.0
HKD2_k127_2663393_11 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000002602 133.0
HKD2_k127_2663393_12 - - - - 0.00000000000000000000000007608 117.0
HKD2_k127_2663393_13 - - - - 0.0000000000000000000000002235 117.0
HKD2_k127_2663393_14 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000006421 103.0
HKD2_k127_2663393_15 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000002457 97.0
HKD2_k127_2663393_16 Glycosyltransferase Family 4 - - - 0.0000000000002885 81.0
HKD2_k127_2663393_2 MMPL family K06994,K20470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 429.0
HKD2_k127_2663393_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 369.0
HKD2_k127_2663393_4 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 349.0
HKD2_k127_2663393_5 COG4257 Streptogramin lyase K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 349.0
HKD2_k127_2663393_6 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 327.0
HKD2_k127_2663393_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 299.0
HKD2_k127_2663393_8 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002469 292.0
HKD2_k127_2663393_9 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000000000001802 126.0
HKD2_k127_2681326_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1140.0
HKD2_k127_2681326_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 7.177e-288 905.0
HKD2_k127_2681326_10 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 336.0
HKD2_k127_2681326_11 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 321.0
HKD2_k127_2681326_12 TIGRFAM RHS repeat-associated core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 346.0
HKD2_k127_2681326_13 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009199 289.0
HKD2_k127_2681326_14 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005398 283.0
HKD2_k127_2681326_15 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001424 280.0
HKD2_k127_2681326_16 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000004975 256.0
HKD2_k127_2681326_17 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
HKD2_k127_2681326_18 containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001391 238.0
HKD2_k127_2681326_19 Pfam:Pyridox_oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000001518 241.0
HKD2_k127_2681326_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.68e-282 888.0
HKD2_k127_2681326_20 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000005952 243.0
HKD2_k127_2681326_21 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000001559 242.0
HKD2_k127_2681326_22 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000005476 227.0
HKD2_k127_2681326_23 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000006359 203.0
HKD2_k127_2681326_24 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000002746 198.0
HKD2_k127_2681326_25 methyltransferase - - - 0.000000000000000000000000000000000000000000000004377 180.0
HKD2_k127_2681326_26 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000009582 179.0
HKD2_k127_2681326_27 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000006477 167.0
HKD2_k127_2681326_28 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000000806 164.0
HKD2_k127_2681326_29 AefR-like transcriptional repressor, C-terminal region - - - 0.00000000000000000000000000000000000000001716 160.0
HKD2_k127_2681326_3 Aminotransferase class-III K00819 - 2.6.1.13 1.899e-203 642.0
HKD2_k127_2681326_30 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000008217 147.0
HKD2_k127_2681326_31 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000001924 152.0
HKD2_k127_2681326_32 - - - - 0.0000000000000000000000000000004589 139.0
HKD2_k127_2681326_33 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000006942 138.0
HKD2_k127_2681326_34 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000001241 128.0
HKD2_k127_2681326_35 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000002687 114.0
HKD2_k127_2681326_36 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000003824 108.0
HKD2_k127_2681326_38 ThiS family K03636 - - 0.00000000000000000001191 106.0
HKD2_k127_2681326_39 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000002444 94.0
HKD2_k127_2681326_4 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 571.0
HKD2_k127_2681326_40 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000003726 101.0
HKD2_k127_2681326_41 Polymer-forming cytoskeletal - - - 0.0000000000000002359 92.0
HKD2_k127_2681326_42 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000006902 91.0
HKD2_k127_2681326_43 R3H domain K06346 - - 0.000000000000005844 85.0
HKD2_k127_2681326_44 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000001227 70.0
HKD2_k127_2681326_45 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000001467 68.0
HKD2_k127_2681326_46 CAAX protease self-immunity K07052 - - 0.000006136 60.0
HKD2_k127_2681326_47 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0004335 47.0
HKD2_k127_2681326_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 520.0
HKD2_k127_2681326_6 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 471.0
HKD2_k127_2681326_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 437.0
HKD2_k127_2681326_8 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 408.0
HKD2_k127_2681326_9 Sulfotransferase domain K01014 - 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 391.0
HKD2_k127_2687552_0 PFAM transcriptional regulator domain protein - - - 1.723e-258 895.0
HKD2_k127_2687552_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 578.0
HKD2_k127_2687552_2 propanoyl-CoA C-acyltransferase activity K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 389.0
HKD2_k127_2687552_3 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 335.0
HKD2_k127_2687552_4 CBS-domain-containing membrane protein K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 312.0
HKD2_k127_2687552_5 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002249 280.0
HKD2_k127_2687552_6 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
HKD2_k127_2687552_7 Glycosyltransferase, MGT family - - - 0.0000000000000000000000000000000000000118 159.0
HKD2_k127_2687552_8 Tetratricopeptide repeat - - - 0.0000000000000000001574 104.0
HKD2_k127_2699693_0 CoA-transferase family III K18702 - 2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 482.0
HKD2_k127_2699693_1 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 427.0
HKD2_k127_2699693_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 386.0
HKD2_k127_2699693_3 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 340.0
HKD2_k127_2699693_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K13766 - 4.2.1.17,4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000004763 252.0
HKD2_k127_2699693_5 acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000858 211.0
HKD2_k127_2699693_6 G3E family - - - 0.000000000000000000000000000000008807 140.0
HKD2_k127_2699693_7 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0032259,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043621,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0046872,GO:0046914,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.000000000006623 65.0
HKD2_k127_2745856_0 arylsulfatase A - - - 2.794e-220 714.0
HKD2_k127_2745856_1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 1.935e-204 644.0
HKD2_k127_2745856_10 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000003117 147.0
HKD2_k127_2745856_11 helicase activity - - - 0.00000000000000000000000003869 126.0
HKD2_k127_2745856_12 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000005937 108.0
HKD2_k127_2745856_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 544.0
HKD2_k127_2745856_3 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 500.0
HKD2_k127_2745856_4 COG0625 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 411.0
HKD2_k127_2745856_5 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 353.0
HKD2_k127_2745856_6 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003834 276.0
HKD2_k127_2745856_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000288 233.0
HKD2_k127_2745856_8 - - - - 0.00000000000000000000000000000000000000000006695 179.0
HKD2_k127_2745856_9 - - - - 0.0000000000000000000000000000000000000003042 160.0
HKD2_k127_2746919_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 1.001e-226 744.0
HKD2_k127_2746919_1 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 596.0
HKD2_k127_2746919_10 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007021 304.0
HKD2_k127_2746919_11 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000003575 245.0
HKD2_k127_2746919_12 acyl-CoA hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000003626 222.0
HKD2_k127_2746919_13 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000000000004003 205.0
HKD2_k127_2746919_14 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000001657 196.0
HKD2_k127_2746919_15 2OG-Fe(II) oxygenase K07394 - - 0.000000000000000000000000000000000000000000000001755 182.0
HKD2_k127_2746919_16 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000004276 186.0
HKD2_k127_2746919_17 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000002794 105.0
HKD2_k127_2746919_18 Bacterial PH domain - - - 0.00000000000000000003138 96.0
HKD2_k127_2746919_19 protocatechuate 3,4-dioxygenase activity K03333 - 1.1.3.6 0.00000000000000004156 85.0
HKD2_k127_2746919_2 FGGY family of carbohydrate kinases, C-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 563.0
HKD2_k127_2746919_20 Methionine synthase - - - 0.00003529 49.0
HKD2_k127_2746919_3 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 514.0
HKD2_k127_2746919_4 Cytochrome P450 K20497 - 1.14.15.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 492.0
HKD2_k127_2746919_5 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 398.0
HKD2_k127_2746919_6 Methionine synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 375.0
HKD2_k127_2746919_7 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 299.0
HKD2_k127_2746919_8 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 295.0
HKD2_k127_2746919_9 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 319.0
HKD2_k127_2761193_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.392e-221 699.0
HKD2_k127_2761193_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 636.0
HKD2_k127_2761193_10 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000006368 195.0
HKD2_k127_2761193_11 prephenate dehydrogenase K00220 - 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000009365 195.0
HKD2_k127_2761193_12 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000005671 173.0
HKD2_k127_2761193_13 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000008002 183.0
HKD2_k127_2761193_14 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000002265 168.0
HKD2_k127_2761193_15 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000005538 124.0
HKD2_k127_2761193_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.0000000000000000000000000009391 124.0
HKD2_k127_2761193_17 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000002863 121.0
HKD2_k127_2761193_18 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000008095 124.0
HKD2_k127_2761193_19 AAA domain - - - 0.00000000000000000000003872 115.0
HKD2_k127_2761193_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 578.0
HKD2_k127_2761193_20 Pfam:DUF1049 K08992 - - 0.0001531 49.0
HKD2_k127_2761193_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 416.0
HKD2_k127_2761193_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 355.0
HKD2_k127_2761193_5 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 336.0
HKD2_k127_2761193_6 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000002304 263.0
HKD2_k127_2761193_7 recombinase XerD K04763 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000004878 261.0
HKD2_k127_2761193_8 GDP-mannose 4,6 dehydratase K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000008214 218.0
HKD2_k127_2761193_9 dCMP deaminase activity K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000001016 203.0
HKD2_k127_2778745_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1283.0
HKD2_k127_2778745_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1234.0
HKD2_k127_2778745_10 COG2211 Na melibiose symporter and related transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002676 261.0
HKD2_k127_2778745_11 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000003383 246.0
HKD2_k127_2778745_12 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000005055 232.0
HKD2_k127_2778745_13 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000005991 216.0
HKD2_k127_2778745_14 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000001794 212.0
HKD2_k127_2778745_15 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000005752 201.0
HKD2_k127_2778745_16 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000009719 196.0
HKD2_k127_2778745_17 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000104 201.0
HKD2_k127_2778745_18 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000003098 181.0
HKD2_k127_2778745_19 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000004143 162.0
HKD2_k127_2778745_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.639e-303 944.0
HKD2_k127_2778745_20 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000008327 164.0
HKD2_k127_2778745_21 Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000001923 153.0
HKD2_k127_2778745_22 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000374 129.0
HKD2_k127_2778745_23 PFAM Methyltransferase type - - - 0.00000000000000000000000001583 116.0
HKD2_k127_2778745_24 Glutathione peroxidase - - - 0.0000000000000000000000007835 119.0
HKD2_k127_2778745_25 Sulfotransferase family - - - 0.00000000000000000004959 104.0
HKD2_k127_2778745_28 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000001875 64.0
HKD2_k127_2778745_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 559.0
HKD2_k127_2778745_4 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 546.0
HKD2_k127_2778745_5 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 319.0
HKD2_k127_2778745_6 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008398 291.0
HKD2_k127_2778745_7 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003833 276.0
HKD2_k127_2778745_8 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008635 280.0
HKD2_k127_2778745_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008135 252.0
HKD2_k127_2799717_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1312.0
HKD2_k127_2799717_1 Glycoside hydrolase family 44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 516.0
HKD2_k127_2799717_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000007352 78.0
HKD2_k127_2799717_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 392.0
HKD2_k127_2799717_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 371.0
HKD2_k127_2799717_4 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 361.0
HKD2_k127_2799717_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002835 291.0
HKD2_k127_2799717_6 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003379 286.0
HKD2_k127_2799717_7 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000001562 230.0
HKD2_k127_2799717_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000001856 94.0
HKD2_k127_2799751_0 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 354.0
HKD2_k127_2799751_1 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000152 282.0
HKD2_k127_2799751_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006198 289.0
HKD2_k127_2799751_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001298 278.0
HKD2_k127_2799751_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000002043 121.0
HKD2_k127_2799751_5 Protein of unknown function (DUF4242) - - - 0.00000000000009916 79.0
HKD2_k127_2799751_6 BolA-like protein - - - 0.00000000002599 66.0
HKD2_k127_2799751_7 isocitrate K00031 - 1.1.1.42 0.000004897 59.0
HKD2_k127_2799751_8 PLC-like phosphodiesterase - - - 0.0002207 45.0
HKD2_k127_2812768_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1033.0
HKD2_k127_2812768_1 Belongs to the glycosyl hydrolase 43 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 370.0
HKD2_k127_2812768_10 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000000001525 130.0
HKD2_k127_2812768_11 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000002161 114.0
HKD2_k127_2812768_12 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000001956 58.0
HKD2_k127_2812768_2 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
HKD2_k127_2812768_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 314.0
HKD2_k127_2812768_4 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001829 286.0
HKD2_k127_2812768_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002706 285.0
HKD2_k127_2812768_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 271.0
HKD2_k127_2812768_7 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 269.0
HKD2_k127_2812768_8 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002077 257.0
HKD2_k127_2812768_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000001247 190.0
HKD2_k127_2892190_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 500.0
HKD2_k127_2892190_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 443.0
HKD2_k127_2892190_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000001624 258.0
HKD2_k127_2892190_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
HKD2_k127_2892190_12 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007135 265.0
HKD2_k127_2892190_13 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009994 274.0
HKD2_k127_2892190_14 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000206 245.0
HKD2_k127_2892190_15 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000002279 233.0
HKD2_k127_2892190_16 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000001161 214.0
HKD2_k127_2892190_17 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000008923 196.0
HKD2_k127_2892190_18 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000004102 176.0
HKD2_k127_2892190_19 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000002374 147.0
HKD2_k127_2892190_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009748 392.0
HKD2_k127_2892190_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000000007788 107.0
HKD2_k127_2892190_21 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000007735 104.0
HKD2_k127_2892190_22 PFAM Outer membrane K06142 - - 0.000000000000005618 82.0
HKD2_k127_2892190_23 HEAT repeat - - - 0.0000000001024 70.0
HKD2_k127_2892190_24 Lipopolysaccharide-assembly - - - 0.00004291 53.0
HKD2_k127_2892190_25 Binds directly to 16S ribosomal RNA K02968 - - 0.000222 48.0
HKD2_k127_2892190_3 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 368.0
HKD2_k127_2892190_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 351.0
HKD2_k127_2892190_5 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 314.0
HKD2_k127_2892190_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005002 281.0
HKD2_k127_2892190_7 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000335 283.0
HKD2_k127_2892190_8 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002814 284.0
HKD2_k127_2892190_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000007664 282.0
HKD2_k127_2975958_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 5.782e-299 941.0
HKD2_k127_2975958_1 elongation factor G domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 584.0
HKD2_k127_2975958_10 - - - - 0.00000000000000000000000000000000000000000000000000003439 207.0
HKD2_k127_2975958_11 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000001238 196.0
HKD2_k127_2975958_12 serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000008144 188.0
HKD2_k127_2975958_13 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000007954 188.0
HKD2_k127_2975958_14 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000006022 148.0
HKD2_k127_2975958_15 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000392 120.0
HKD2_k127_2975958_16 HD domain - - - 0.0000000000000000000006244 111.0
HKD2_k127_2975958_17 - - - - 0.0000000000003208 83.0
HKD2_k127_2975958_18 ubiE/COQ5 methyltransferase family - - - 0.000000000001034 81.0
HKD2_k127_2975958_19 PFAM GGDEF domain containing protein - - - 0.00000000009181 73.0
HKD2_k127_2975958_2 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 484.0
HKD2_k127_2975958_3 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 376.0
HKD2_k127_2975958_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 310.0
HKD2_k127_2975958_5 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002404 281.0
HKD2_k127_2975958_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000001003 271.0
HKD2_k127_2975958_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 259.0
HKD2_k127_2975958_8 Domains Cache_1, HAMP, PAS, PAS K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000002938 259.0
HKD2_k127_2975958_9 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000002856 257.0
HKD2_k127_2996244_0 AAA-like domain - - - 2.104e-248 790.0
HKD2_k127_2996244_1 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 555.0
HKD2_k127_2996244_10 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
HKD2_k127_2996244_11 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002006 272.0
HKD2_k127_2996244_12 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002897 264.0
HKD2_k127_2996244_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
HKD2_k127_2996244_14 PFAM Y_Y_Y domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001866 249.0
HKD2_k127_2996244_15 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000000000000000000007863 228.0
HKD2_k127_2996244_16 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000116 232.0
HKD2_k127_2996244_17 - - - - 0.00000000000000000000000000000000000000000001307 169.0
HKD2_k127_2996244_18 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000003586 161.0
HKD2_k127_2996244_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07281,K07291 - 2.7.7.74,2.7.8.34 0.00000000000000000000000000000000000000001206 170.0
HKD2_k127_2996244_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 511.0
HKD2_k127_2996244_20 DoxX K15977 - - 0.000000000000000000000000000000000000003725 149.0
HKD2_k127_2996244_21 TIGRFAM 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000009827 160.0
HKD2_k127_2996244_22 - - - - 0.0000000000000000000000000000007338 136.0
HKD2_k127_2996244_23 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000006082 93.0
HKD2_k127_2996244_24 Acyl-protein synthetase, LuxE K06046 - 6.2.1.19 0.0000000008707 71.0
HKD2_k127_2996244_25 Histidine kinase - - - 0.00007607 53.0
HKD2_k127_2996244_26 - - - - 0.00008977 49.0
HKD2_k127_2996244_27 Belongs to the ompA family - - - 0.0001296 54.0
HKD2_k127_2996244_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 449.0
HKD2_k127_2996244_4 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 362.0
HKD2_k127_2996244_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 354.0
HKD2_k127_2996244_6 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 361.0
HKD2_k127_2996244_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 328.0
HKD2_k127_2996244_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 317.0
HKD2_k127_2996244_9 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 293.0
HKD2_k127_3016881_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 3.738e-279 893.0
HKD2_k127_3016881_1 Cytochrome P450 K05917 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615 1.14.13.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 547.0
HKD2_k127_3016881_10 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000009966 214.0
HKD2_k127_3016881_11 - - - - 0.00000000000000000000000000000000000000000000000000000001494 207.0
HKD2_k127_3016881_12 Protein of unknown function (DUF1214) - - - 0.0000000000000000000000000000000000000000000000000000001464 220.0
HKD2_k127_3016881_13 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000007415 220.0
HKD2_k127_3016881_14 KR domain - - - 0.000000000000000000000000000000000000000000000000000009375 215.0
HKD2_k127_3016881_15 Bacterial protein of unknown function (DUF899) - - - 0.0000000000000000000000000000000000000000000000000131 200.0
HKD2_k127_3016881_17 nuclear-transcribed mRNA catabolic process, no-go decay - - - 0.00000000000000000000000002696 123.0
HKD2_k127_3016881_18 CBS domain K04767,K07168,K07182 - - 0.000000000000000000000001429 109.0
HKD2_k127_3016881_19 transcriptional regulator - - - 0.00000000000000000000000177 112.0
HKD2_k127_3016881_2 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 491.0
HKD2_k127_3016881_20 HlyD family secretion protein K02005 - - 0.000000000000000000000005375 107.0
HKD2_k127_3016881_21 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000001399 106.0
HKD2_k127_3016881_22 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000003996 88.0
HKD2_k127_3016881_23 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000002095 83.0
HKD2_k127_3016881_24 - - - - 0.00000000005144 68.0
HKD2_k127_3016881_25 zinc ion binding K06204 - - 0.00000008053 63.0
HKD2_k127_3016881_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 393.0
HKD2_k127_3016881_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 355.0
HKD2_k127_3016881_5 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 368.0
HKD2_k127_3016881_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 348.0
HKD2_k127_3016881_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
HKD2_k127_3016881_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 310.0
HKD2_k127_3016881_9 aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 297.0
HKD2_k127_306052_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 452.0
HKD2_k127_306052_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 413.0
HKD2_k127_306052_2 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.0000000000000000000004188 102.0
HKD2_k127_306052_3 ThiS family K03636 - - 0.0000000000000000002717 98.0
HKD2_k127_306052_4 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.0004202 53.0
HKD2_k127_3088149_0 Belongs to the TPP enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 526.0
HKD2_k127_3088149_1 PFAM gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 489.0
HKD2_k127_3088149_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000009163 148.0
HKD2_k127_3088149_11 hydrolase (HAD superfamily) K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.000000000000000000000000000000000003744 155.0
HKD2_k127_3088149_12 Belongs to the ompA family K03640 - - 0.00000000000000000000000000004981 127.0
HKD2_k127_3088149_13 ig-like, plexins, transcription factors - - - 0.0000000000000000000000004315 123.0
HKD2_k127_3088149_2 Amidohydrolase family K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 474.0
HKD2_k127_3088149_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 415.0
HKD2_k127_3088149_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 417.0
HKD2_k127_3088149_5 pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 373.0
HKD2_k127_3088149_6 Has an organic peroxide-dependent peroxidase activity K03781 - 1.11.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002143 281.0
HKD2_k127_3088149_7 Cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002091 280.0
HKD2_k127_3088149_8 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
HKD2_k127_3088149_9 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000855 246.0
HKD2_k127_3166849_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1049.0
HKD2_k127_3166849_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 1.108e-259 815.0
HKD2_k127_3166849_10 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000001162 241.0
HKD2_k127_3166849_2 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 2.95e-247 782.0
HKD2_k127_3166849_3 Belongs to the ABC transporter superfamily K13896 - - 2.941e-228 736.0
HKD2_k127_3166849_4 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 670.0
HKD2_k127_3166849_5 transport system, permease component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 545.0
HKD2_k127_3166849_6 transport system, permease component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 512.0
HKD2_k127_3166849_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 454.0
HKD2_k127_3166849_8 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 379.0
HKD2_k127_3166849_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001468 275.0
HKD2_k127_3226817_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 2.597e-228 728.0
HKD2_k127_3226817_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.209e-195 644.0
HKD2_k127_3226817_10 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 308.0
HKD2_k127_3226817_11 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000002552 268.0
HKD2_k127_3226817_12 riboflavin synthase, alpha K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000008002 192.0
HKD2_k127_3226817_13 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.0000000000000000000000000000000000000007401 164.0
HKD2_k127_3226817_14 Belongs to the UPF0109 family K06960 - - 0.00000000000000000001475 94.0
HKD2_k127_3226817_15 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000004097 76.0
HKD2_k127_3226817_16 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000006587 80.0
HKD2_k127_3226817_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000006901 78.0
HKD2_k127_3226817_18 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000008209 72.0
HKD2_k127_3226817_19 Tetratricopeptide repeat - - - 0.0000000003042 71.0
HKD2_k127_3226817_2 aminotransferase K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 537.0
HKD2_k127_3226817_20 Domain of unknown function (DUF4136) - - - 0.000000001825 72.0
HKD2_k127_3226817_21 Anthrax toxin receptor K20909 - - 0.0001985 53.0
HKD2_k127_3226817_22 Periplasmic protein - - - 0.0004689 51.0
HKD2_k127_3226817_3 glycosyl hydrolase 38 domain protein K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 539.0
HKD2_k127_3226817_4 amino acid-binding ACT domain protein K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 474.0
HKD2_k127_3226817_5 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000879 462.0
HKD2_k127_3226817_6 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 364.0
HKD2_k127_3226817_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 329.0
HKD2_k127_3226817_8 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 319.0
HKD2_k127_3226817_9 COG0695 glutaredoxin and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 306.0
HKD2_k127_3227429_0 Domain of unknown function (DUF3427) - - - 0.0 1393.0
HKD2_k127_3227429_1 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 541.0
HKD2_k127_3227429_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 312.0
HKD2_k127_3227429_11 'glutamate synthase K00123,K00317,K00528,K09835 - 1.17.1.9,1.18.1.2,1.19.1.1,1.5.8.1,1.5.8.2,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 316.0
HKD2_k127_3227429_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003327 268.0
HKD2_k127_3227429_13 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004842 274.0
HKD2_k127_3227429_14 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000005691 241.0
HKD2_k127_3227429_15 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000002424 242.0
HKD2_k127_3227429_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000003481 232.0
HKD2_k127_3227429_17 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000009593 221.0
HKD2_k127_3227429_18 Alpha beta hydrolase K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000001234 201.0
HKD2_k127_3227429_19 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.00000000000000000000000000000000000000000000000000001792 216.0
HKD2_k127_3227429_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 541.0
HKD2_k127_3227429_20 Protein of unknown function (DUF456) K09793 - - 0.0000000000000001971 88.0
HKD2_k127_3227429_21 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000007677 79.0
HKD2_k127_3227429_22 - - - - 0.00001135 57.0
HKD2_k127_3227429_23 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0003469 52.0
HKD2_k127_3227429_3 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 473.0
HKD2_k127_3227429_4 Chalcone and stilbene synthases, C-terminal domain K16167,K19580 - 2.3.1.233 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 440.0
HKD2_k127_3227429_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 399.0
HKD2_k127_3227429_6 Histidinol dehydrogenase K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 398.0
HKD2_k127_3227429_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 332.0
HKD2_k127_3227429_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 355.0
HKD2_k127_3227429_9 zinc finger K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 334.0
HKD2_k127_3320400_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 522.0
HKD2_k127_3320400_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 492.0
HKD2_k127_3320400_10 rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000003798 196.0
HKD2_k127_3320400_11 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000326 180.0
HKD2_k127_3320400_12 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000002095 169.0
HKD2_k127_3320400_13 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000001605 151.0
HKD2_k127_3320400_14 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000005233 130.0
HKD2_k127_3320400_15 Luciferase-like monooxygenase - - - 0.000000000000000000000000000004552 140.0
HKD2_k127_3320400_16 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000001207 113.0
HKD2_k127_3320400_17 - - - - 0.00000000000000000002218 91.0
HKD2_k127_3320400_18 PFAM Cytochrome c assembly protein - - - 0.000000000000000698 90.0
HKD2_k127_3320400_19 C-terminal domain of histone - - - 0.0001501 54.0
HKD2_k127_3320400_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 408.0
HKD2_k127_3320400_3 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 394.0
HKD2_k127_3320400_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 361.0
HKD2_k127_3320400_5 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
HKD2_k127_3320400_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 311.0
HKD2_k127_3320400_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000002459 268.0
HKD2_k127_3320400_8 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003478 254.0
HKD2_k127_3320400_9 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000003234 198.0
HKD2_k127_3396828_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 555.0
HKD2_k127_3396828_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 458.0
HKD2_k127_3396828_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000001976 169.0
HKD2_k127_3396828_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000001877 166.0
HKD2_k127_3396828_12 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000001043 109.0
HKD2_k127_3396828_13 Pfam:N_methyl_2 K02650 - - 0.000000000000000000000152 109.0
HKD2_k127_3396828_14 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000002106 105.0
HKD2_k127_3396828_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000002256 110.0
HKD2_k127_3396828_16 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000001119 107.0
HKD2_k127_3396828_17 serine threonine protein kinase - - - 0.0000000000000002259 91.0
HKD2_k127_3396828_18 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000001015 78.0
HKD2_k127_3396828_19 Type IV minor pilin ComP, DNA uptake sequence receptor K02650 - - 0.00000000000009503 79.0
HKD2_k127_3396828_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 402.0
HKD2_k127_3396828_20 Cytosol aminopeptidase family, N-terminal domain - - - 0.00000000000485 76.0
HKD2_k127_3396828_21 Tetratricopeptide repeat - - - 0.0000828 54.0
HKD2_k127_3396828_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 304.0
HKD2_k127_3396828_4 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003704 284.0
HKD2_k127_3396828_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001954 282.0
HKD2_k127_3396828_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000322 250.0
HKD2_k127_3396828_7 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000001739 198.0
HKD2_k127_3396828_8 - - - - 0.000000000000000000000000000000000000000000000001203 195.0
HKD2_k127_3396828_9 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000148 179.0
HKD2_k127_3420125_0 DNA topoisomerase K02622 - - 2.867e-240 757.0
HKD2_k127_3420125_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 2.103e-196 632.0
HKD2_k127_3420125_10 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 329.0
HKD2_k127_3420125_11 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000006452 265.0
HKD2_k127_3420125_12 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002446 256.0
HKD2_k127_3420125_13 Flavodoxin-like fold K03923,K11748 - - 0.00000000000000000000000000000000000000000000000000000000000000003162 249.0
HKD2_k127_3420125_14 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000002987 217.0
HKD2_k127_3420125_15 Acetoacetate decarboxylase (ADC) - - - 0.000000000000000000000000000000000000000000000000000009523 204.0
HKD2_k127_3420125_16 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000002203 196.0
HKD2_k127_3420125_17 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000001303 205.0
HKD2_k127_3420125_18 EVE domain - - - 0.0000000000000000000000000000000000000000002211 168.0
HKD2_k127_3420125_19 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000001495 171.0
HKD2_k127_3420125_2 'PFAM Alpha amylase, catalytic K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 589.0
HKD2_k127_3420125_20 Rare lipoprotein A (RlpA)-like double-psi beta-barrel K20628 - - 0.000000000000000000000000000000000000179 151.0
HKD2_k127_3420125_21 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000005108 152.0
HKD2_k127_3420125_22 SMART Tetratricopeptide - - - 0.0000000000000000005433 104.0
HKD2_k127_3420125_23 SnoaL-like domain K06893 - - 0.0000000000000000008677 101.0
HKD2_k127_3420125_24 - - - - 0.00000000285 70.0
HKD2_k127_3420125_25 DNA helicase K03654 - 3.6.4.12 0.000002104 50.0
HKD2_k127_3420125_3 DNA polymerase type-B family K02336 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 620.0
HKD2_k127_3420125_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 601.0
HKD2_k127_3420125_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02621 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 586.0
HKD2_k127_3420125_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 513.0
HKD2_k127_3420125_7 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 405.0
HKD2_k127_3420125_8 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 361.0
HKD2_k127_3420125_9 acyl-CoA thioesterase K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 356.0
HKD2_k127_3481273_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 426.0
HKD2_k127_3481273_1 NADPH quinone reductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 380.0
HKD2_k127_3481273_10 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000004004 119.0
HKD2_k127_3481273_11 Domain of unknown function (DUF4034) - - - 0.00000000000000000001191 106.0
HKD2_k127_3481273_12 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000001313 77.0
HKD2_k127_3481273_2 Belongs to the thiolase family K08764 GO:0000038,GO:0000062,GO:0000166,GO:0001676,GO:0002119,GO:0002164,GO:0003008,GO:0003674,GO:0003824,GO:0003988,GO:0005102,GO:0005215,GO:0005319,GO:0005488,GO:0005496,GO:0005504,GO:0005515,GO:0005548,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006163,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006694,GO:0006699,GO:0006700,GO:0006701,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006886,GO:0006996,GO:0007031,GO:0007275,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008104,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008207,GO:0008289,GO:0008306,GO:0008355,GO:0008525,GO:0008526,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009719,GO:0009725,GO:0009791,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010817,GO:0010876,GO:0010883,GO:0010888,GO:0010893,GO:0010941,GO:0010942,GO:0012505,GO:0014070,GO:0015031,GO:0015248,GO:0015485,GO:0015711,GO:0015748,GO:0015833,GO:0015850,GO:0015914,GO:0015918,GO:0016020,GO:0016042,GO:0016043,GO:0016053,GO:0016054,GO:0016137,GO:0016138,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0017127,GO:0017144,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019395,GO:0019637,GO:0019693,GO:0019748,GO:0019751,GO:0019752,GO:0019867,GO:0019898,GO:0022611,GO:0030258,GO:0030301,GO:0030554,GO:0031090,GO:0031312,GO:0031315,GO:0031406,GO:0031907,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032101,GO:0032355,GO:0032368,GO:0032370,GO:0032371,GO:0032373,GO:0032374,GO:0032376,GO:0032377,GO:0032379,GO:0032380,GO:0032382,GO:0032383,GO:0032385,GO:0032386,GO:0032388,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032879,GO:0032934,GO:0032957,GO:0032958,GO:0032959,GO:0032991,GO:0033036,GO:0033218,GO:0033293,GO:0033365,GO:0033540,GO:0033559,GO:0033814,GO:0033865,GO:0033875,GO:0033993,GO:0034032,GO:0034440,GO:0034613,GO:0034641,GO:0034698,GO:0034699,GO:0034754,GO:0035383,GO:0036041,GO:0036042,GO:0036094,GO:0036109,GO:0036314,GO:0036315,GO:0040008,GO:0040012,GO:0040024,GO:0042048,GO:0042180,GO:0042181,GO:0042221,GO:0042445,GO:0042446,GO:0042448,GO:0042579,GO:0042802,GO:0042803,GO:0042810,GO:0042811,GO:0042886,GO:0042981,GO:0043053,GO:0043054,GO:0043065,GO:0043067,GO:0043068,GO:0043167,GO:0043168,GO:0043177,GO:0043178,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043434,GO:0043436,GO:0043574,GO:0043603,GO:0043647,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044550,GO:0045184,GO:0045540,GO:0045542,GO:0045834,GO:0045927,GO:0045940,GO:0046165,GO:0046173,GO:0046394,GO:0046395,GO:0046483,GO:0046889,GO:0046890,GO:0046907,GO:0046982,GO:0046983,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048580,GO:0048582,GO:0048583,GO:0048638,GO:0048639,GO:0048856,GO:0050632,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050810,GO:0050877,GO:0050890,GO:0050896,GO:0050920,GO:0051049,GO:0051050,GO:0051094,GO:0051179,GO:0051186,GO:0051234,GO:0051239,GO:0051240,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0055115,GO:0060341,GO:0060620,GO:0061062,GO:0061063,GO:0062012,GO:0062013,GO:0065007,GO:0065008,GO:0070013,GO:0070538,GO:0070723,GO:0070727,GO:0070887,GO:0071310,GO:0071396,GO:0071397,GO:0071407,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071981,GO:0072329,GO:0072330,GO:0072521,GO:0072594,GO:0072657,GO:0072659,GO:0072662,GO:0072663,GO:0080090,GO:0090181,GO:0090205,GO:0090407,GO:0097159,GO:0097305,GO:0097306,GO:0097367,GO:0098588,GO:0098805,GO:0106118,GO:0106120,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901373,GO:1901564,GO:1901567,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901652,GO:1901657,GO:1901659,GO:1901681,GO:1901698,GO:1901700,GO:1901701,GO:1902930,GO:1902932,GO:1904069,GO:1904070,GO:1904109,GO:1904121,GO:1905952,GO:1905953,GO:1905954,GO:1990778,GO:2000026,GO:2000909,GO:2000911 2.3.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003058 306.0
HKD2_k127_3481273_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000344 227.0
HKD2_k127_3481273_4 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000001812 235.0
HKD2_k127_3481273_5 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000006981 199.0
HKD2_k127_3481273_6 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000004876 216.0
HKD2_k127_3481273_7 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000001536 172.0
HKD2_k127_3481273_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000003254 166.0
HKD2_k127_3481273_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000004055 161.0
HKD2_k127_351700_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 583.0
HKD2_k127_351700_1 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 317.0
HKD2_k127_351700_10 CoA binding domain K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000005707 134.0
HKD2_k127_351700_12 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.0000000000000002623 93.0
HKD2_k127_351700_13 Bacterial regulatory proteins, tetR family - - - 0.0000000000001563 79.0
HKD2_k127_351700_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 301.0
HKD2_k127_351700_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000164 252.0
HKD2_k127_351700_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001349 244.0
HKD2_k127_351700_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000001205 261.0
HKD2_k127_351700_6 NAD dependent epimerase/dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000002923 239.0
HKD2_k127_351700_7 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000005738 189.0
HKD2_k127_351700_8 TraB family K09973 - - 0.000000000000000000000000000000000000005994 168.0
HKD2_k127_351700_9 glycosyl transferase family 39 K00721 - 2.4.1.83 0.0000000000000000000000000000000000001631 162.0
HKD2_k127_3540939_0 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 601.0
HKD2_k127_3540939_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 298.0
HKD2_k127_3540939_2 PFAM ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.00000000000000000000000000000000000003801 158.0
HKD2_k127_3540939_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000002912 126.0
HKD2_k127_3540939_4 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000111 94.0
HKD2_k127_3540939_5 - - - - 0.000001603 56.0
HKD2_k127_3561294_0 Lysylphosphatidylglycerol synthase TM region K07027,K14205 - 2.3.2.3 1.996e-253 808.0
HKD2_k127_3561294_1 Bacterial virulence protein (VirJ) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 336.0
HKD2_k127_3561294_2 - - - - 0.0000000000000000000000000000000000000002446 169.0
HKD2_k127_3561294_3 PFAM RNA recognition motif - - - 0.00000000000000000000000001697 117.0
HKD2_k127_356880_0 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 420.0
HKD2_k127_356880_1 RHS protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 373.0
HKD2_k127_356880_10 amine dehydrogenase activity - - - 0.00000000001254 71.0
HKD2_k127_356880_2 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 336.0
HKD2_k127_356880_3 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 329.0
HKD2_k127_356880_4 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 324.0
HKD2_k127_356880_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 315.0
HKD2_k127_356880_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001201 263.0
HKD2_k127_356880_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000001621 215.0
HKD2_k127_356880_8 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000009472 194.0
HKD2_k127_356880_9 AraC-like ligand binding domain - - - 0.0000000000006978 73.0
HKD2_k127_359539_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 2.225e-264 849.0
HKD2_k127_359539_1 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 3.328e-254 798.0
HKD2_k127_359539_10 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000007193 188.0
HKD2_k127_359539_11 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000001664 187.0
HKD2_k127_359539_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000002164 179.0
HKD2_k127_359539_13 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000003714 162.0
HKD2_k127_359539_14 Nitroreductase family - - - 0.0000000000000000000000000000000002838 143.0
HKD2_k127_359539_15 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000243 107.0
HKD2_k127_359539_16 WHG domain - - - 0.00000000000000005571 89.0
HKD2_k127_359539_17 glyoxalase III activity - - - 0.0000000188 61.0
HKD2_k127_359539_18 tetR family - - - 0.000000392 63.0
HKD2_k127_359539_19 Outer mitochondrial membrane transport complex protein - - - 0.000000579 61.0
HKD2_k127_359539_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.419e-218 729.0
HKD2_k127_359539_20 Redoxin - - - 0.0001808 48.0
HKD2_k127_359539_3 Luciferase-like monooxygenase K14733 - 1.14.13.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 579.0
HKD2_k127_359539_4 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 370.0
HKD2_k127_359539_5 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 332.0
HKD2_k127_359539_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000986 301.0
HKD2_k127_359539_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004241 259.0
HKD2_k127_359539_8 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
HKD2_k127_359539_9 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000001884 225.0
HKD2_k127_382807_0 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 466.0
HKD2_k127_382807_1 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 355.0
HKD2_k127_382807_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000002757 207.0
HKD2_k127_382807_3 MaoC like domain - - - 0.00000000000000000000000000000000000000000459 177.0
HKD2_k127_382807_4 cytochrome p450 - - - 0.0000000000000000000000000000000004128 138.0
HKD2_k127_382807_5 dehydratase - - - 0.0000000000000000000000000000008411 127.0
HKD2_k127_382807_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000008721 78.0
HKD2_k127_382807_7 Transcriptional regulator, Fis family - - - 0.0000501 55.0
HKD2_k127_3836734_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.381e-264 823.0
HKD2_k127_3836734_1 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 576.0
HKD2_k127_3836734_10 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000001482 178.0
HKD2_k127_3836734_11 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000003473 143.0
HKD2_k127_3836734_12 HAD-hyrolase-like K20862 - 3.1.3.102,3.1.3.104 0.00000000005745 66.0
HKD2_k127_3836734_13 HEAT repeats - - - 0.0002724 53.0
HKD2_k127_3836734_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 473.0
HKD2_k127_3836734_3 CoA-transferase family III K07749,K08298 - 2.8.3.16,2.8.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 455.0
HKD2_k127_3836734_4 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 389.0
HKD2_k127_3836734_5 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 346.0
HKD2_k127_3836734_6 Psort location CytoplasmicMembrane, score 10.00 K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001707 265.0
HKD2_k127_3836734_7 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000000000496 245.0
HKD2_k127_3836734_8 Oxygenase, catalysing oxidative methylation of damaged DNA K09990 - - 0.0000000000000000000000000000000000000000000000000000000000000000008735 261.0
HKD2_k127_3836734_9 Lactamase, beta 2 - GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000003008 223.0
HKD2_k127_3840679_0 Sulfate permease family K01673,K03321 - 4.2.1.1 3.8e-199 663.0
HKD2_k127_3840679_1 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 549.0
HKD2_k127_3840679_10 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003392 244.0
HKD2_k127_3840679_11 GHMP kinase K00869,K07031 - 2.7.1.168,2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000006663 250.0
HKD2_k127_3840679_12 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000000000000000000000000000000000000000000005337 223.0
HKD2_k127_3840679_13 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000001214 200.0
HKD2_k127_3840679_14 COGs COG2343 conserved - - - 0.0000000000000000000000000000000000000003589 150.0
HKD2_k127_3840679_15 Histidine kinase - - - 0.000000000000000000000000000000000000002937 165.0
HKD2_k127_3840679_16 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000002703 145.0
HKD2_k127_3840679_17 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000008098 152.0
HKD2_k127_3840679_18 - - - - 0.00000000000000000000000002171 124.0
HKD2_k127_3840679_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 514.0
HKD2_k127_3840679_20 gamma-glutamylcyclotransferase activity - - - 0.00000000000000000000005336 113.0
HKD2_k127_3840679_21 - - - - 0.000000000000000001196 98.0
HKD2_k127_3840679_22 EamA-like transporter family - - - 0.00000000000004248 84.0
HKD2_k127_3840679_23 thiolester hydrolase activity K03186 - 2.5.1.129 0.00000000001587 77.0
HKD2_k127_3840679_24 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.00001259 51.0
HKD2_k127_3840679_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 436.0
HKD2_k127_3840679_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 383.0
HKD2_k127_3840679_5 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 382.0
HKD2_k127_3840679_6 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 348.0
HKD2_k127_3840679_7 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 353.0
HKD2_k127_3840679_8 Belongs to the MenA family. Type 1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 310.0
HKD2_k127_3840679_9 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004381 283.0
HKD2_k127_3911149_0 COG2015 Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 563.0
HKD2_k127_3911149_1 Protein of unknown function (DUF1587) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 486.0
HKD2_k127_3911149_2 Protein of unknown function (DUF1552) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 429.0
HKD2_k127_3911149_3 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000001461 186.0
HKD2_k127_3911149_4 - - - - 0.000000000000000002091 102.0
HKD2_k127_3911149_5 ig-like, plexins, transcription factors - - - 0.00000001776 68.0
HKD2_k127_391145_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 539.0
HKD2_k127_391145_1 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 418.0
HKD2_k127_391145_10 FMN reductase (NADPH) activity - - - 0.0000000000000000000000000000000000000000000000000001314 192.0
HKD2_k127_391145_11 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000001896 160.0
HKD2_k127_391145_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000004912 149.0
HKD2_k127_391145_13 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000001021 76.0
HKD2_k127_391145_2 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 424.0
HKD2_k127_391145_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 346.0
HKD2_k127_391145_4 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 359.0
HKD2_k127_391145_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 317.0
HKD2_k127_391145_6 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
HKD2_k127_391145_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002653 278.0
HKD2_k127_391145_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000002102 244.0
HKD2_k127_391145_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000002718 196.0
HKD2_k127_3967383_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.954e-243 771.0
HKD2_k127_3967383_1 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 424.0
HKD2_k127_3967383_10 SMART ATP-binding region ATPase domain protein, histidine kinase A domain protein, histidine kinase HAMP region domain protein K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000006703 201.0
HKD2_k127_3967383_11 Glycosyl transferase family 2 K09931 - - 0.000000000000000000000000000000000000000000000004663 181.0
HKD2_k127_3967383_12 Domain of unknown function (DUF4185) - - - 0.000000000000000000000000000000000000000000000006014 188.0
HKD2_k127_3967383_13 Guanylate kinase homologues. K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000001468 183.0
HKD2_k127_3967383_14 transferase activity, transferring glycosyl groups K00754 - - 0.0000000000000000000000000000000000000000009249 171.0
HKD2_k127_3967383_15 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000006579 164.0
HKD2_k127_3967383_16 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000006995 107.0
HKD2_k127_3967383_17 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000002725 119.0
HKD2_k127_3967383_18 ABC transporter, transmembrane K18890 - - 0.000002763 59.0
HKD2_k127_3967383_2 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 415.0
HKD2_k127_3967383_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 379.0
HKD2_k127_3967383_4 ABC transporter transmembrane region K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 374.0
HKD2_k127_3967383_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004528 251.0
HKD2_k127_3967383_6 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000006367 231.0
HKD2_k127_3967383_7 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000001267 241.0
HKD2_k127_3967383_8 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000001242 213.0
HKD2_k127_3967383_9 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000002856 206.0
HKD2_k127_4019934_0 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 503.0
HKD2_k127_4019934_1 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 458.0
HKD2_k127_4019934_10 - - - - 0.00000000000000000000004263 113.0
HKD2_k127_4019934_11 transcriptional regulator K04033 - - 0.000000000000000004957 99.0
HKD2_k127_4019934_12 amidinotransferase - GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813 - 0.0000000000003926 77.0
HKD2_k127_4019934_13 Domain of unknown function (DUF4410) - - - 0.000006955 58.0
HKD2_k127_4019934_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 465.0
HKD2_k127_4019934_3 lytic transglycosylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001061 289.0
HKD2_k127_4019934_4 ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003041 256.0
HKD2_k127_4019934_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 GO:0006139,GO:0006351,GO:0006352,GO:0006354,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010604,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031437,GO:0031439,GO:0032774,GO:0032784,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903311,GO:1903313,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000005984 188.0
HKD2_k127_4019934_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000005213 154.0
HKD2_k127_4019934_7 belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000004793 149.0
HKD2_k127_4019934_8 - - - - 0.00000000000000000000000000001213 133.0
HKD2_k127_4019934_9 small membrane protein - - - 0.000000000000000000000000000991 118.0
HKD2_k127_403856_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.09e-321 997.0
HKD2_k127_403856_1 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 501.0
HKD2_k127_403856_10 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000004549 240.0
HKD2_k127_403856_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000006593 241.0
HKD2_k127_403856_12 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000005568 220.0
HKD2_k127_403856_13 Chromosome Partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000002711 222.0
HKD2_k127_403856_14 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000004737 233.0
HKD2_k127_403856_15 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000008487 224.0
HKD2_k127_403856_16 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000003953 208.0
HKD2_k127_403856_17 aldehyde dehydrogenase (NADP+) activity K00289 GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009109,GO:0009256,GO:0009258,GO:0009396,GO:0009397,GO:0009987,GO:0016053,GO:0016054,GO:0016155,GO:0016491,GO:0016620,GO:0016645,GO:0016646,GO:0016903,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019752,GO:0032991,GO:0033721,GO:0034641,GO:0042219,GO:0042398,GO:0042558,GO:0042559,GO:0042560,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046394,GO:0046395,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046700,GO:0051186,GO:0051187,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.5.1.6 0.000000000000000000000000000000000000000000000000000000005604 210.0
HKD2_k127_403856_18 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000377 199.0
HKD2_k127_403856_19 PD-(D/E)XK nuclease superfamily K03657,K07465 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000001451 214.0
HKD2_k127_403856_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 428.0
HKD2_k127_403856_20 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000008399 175.0
HKD2_k127_403856_21 Acyltransferase family - - - 0.00000000000000000000000000000000000000001433 168.0
HKD2_k127_403856_22 AAA domain - - - 0.0000000000000000000000000000000000000008505 172.0
HKD2_k127_403856_23 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000001644 141.0
HKD2_k127_403856_24 Alpha/beta hydrolase family K07020 - - 0.0000000000000000000000000000003221 141.0
HKD2_k127_403856_25 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000002334 126.0
HKD2_k127_403856_26 protein required for cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000008617 128.0
HKD2_k127_403856_27 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000003867 119.0
HKD2_k127_403856_28 Patatin-like phospholipase K07001 - - 0.00000000000000000000479 108.0
HKD2_k127_403856_29 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000001733 108.0
HKD2_k127_403856_3 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 308.0
HKD2_k127_403856_30 PFAM thioesterase superfamily K07107 - - 0.00000000000000001877 96.0
HKD2_k127_403856_31 transcriptional regulator - - - 0.00000000000000005368 96.0
HKD2_k127_403856_32 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000009622 89.0
HKD2_k127_403856_33 Protein of unknown function (DUF1232) - - - 0.0000000000000001623 93.0
HKD2_k127_403856_34 Bacterial transferase hexapeptide repeat protein K00661 - 2.3.1.79 0.000000000000002638 86.0
HKD2_k127_403856_35 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000005852 84.0
HKD2_k127_403856_36 - - - - 0.000000001216 70.0
HKD2_k127_403856_37 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.00000001114 68.0
HKD2_k127_403856_38 NifU-like N terminal domain K04488,K07126,K13819 - - 0.0000001555 59.0
HKD2_k127_403856_39 Cytochrome C biogenesis protein K02200 - - 0.00000543 59.0
HKD2_k127_403856_4 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 301.0
HKD2_k127_403856_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 285.0
HKD2_k127_403856_6 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003062 276.0
HKD2_k127_403856_7 GMC oxidoreductase K06151 - 1.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000001682 267.0
HKD2_k127_403856_8 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000001331 258.0
HKD2_k127_403856_9 Zn-dependent hydrolase, glyoxylase - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000008596 240.0
HKD2_k127_4043955_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 534.0
HKD2_k127_4043955_1 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004306 284.0
HKD2_k127_4043955_2 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000002335 270.0
HKD2_k127_4043955_3 ATPase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000006943 248.0
HKD2_k127_4043955_4 NUDIX domain - - - 0.00000000000000000000000000000000000001774 162.0
HKD2_k127_4043955_5 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000001048 150.0
HKD2_k127_4043955_6 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides - - - 0.0000000000000000000000002383 123.0
HKD2_k127_4043955_7 - - - - 0.000000006674 70.0
HKD2_k127_4043955_8 Dienelactone hydrolase family - - - 0.0000004601 61.0
HKD2_k127_4081108_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 440.0
HKD2_k127_4081108_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 371.0
HKD2_k127_4081108_10 Regulatory protein, FmdB family - - - 0.0000000000000183 83.0
HKD2_k127_4081108_11 DUF167 K09131 - - 0.00000000002029 73.0
HKD2_k127_4081108_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 306.0
HKD2_k127_4081108_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001309 251.0
HKD2_k127_4081108_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000001105 194.0
HKD2_k127_4081108_5 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000000102 172.0
HKD2_k127_4081108_6 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000002596 171.0
HKD2_k127_4081108_7 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000005969 124.0
HKD2_k127_4081108_8 PFAM DivIVA family protein K04074 - - 0.00000000000000000000000001974 117.0
HKD2_k127_4081108_9 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000007959 95.0
HKD2_k127_4093590_0 UvrD/REP helicase N-terminal domain - - - 0.0 1240.0
HKD2_k127_4093590_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 546.0
HKD2_k127_4093590_2 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 536.0
HKD2_k127_4093590_3 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 481.0
HKD2_k127_4093590_4 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 457.0
HKD2_k127_4093590_5 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 366.0
HKD2_k127_4093590_6 Cytochrome P450 - GO:0003674,GO:0003824,GO:0004497,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0046164,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652 - 0.000000000000000000000000000000000000000003543 173.0
HKD2_k127_4203624_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 4.822e-307 985.0
HKD2_k127_4203624_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 9.9e-246 808.0
HKD2_k127_4203624_10 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 405.0
HKD2_k127_4203624_11 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 402.0
HKD2_k127_4203624_12 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 389.0
HKD2_k127_4203624_13 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 341.0
HKD2_k127_4203624_14 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 344.0
HKD2_k127_4203624_15 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 337.0
HKD2_k127_4203624_16 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 329.0
HKD2_k127_4203624_17 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 335.0
HKD2_k127_4203624_18 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 325.0
HKD2_k127_4203624_19 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 347.0
HKD2_k127_4203624_2 oligoendopeptidase F K08602 - - 2.079e-204 654.0
HKD2_k127_4203624_20 desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 325.0
HKD2_k127_4203624_21 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 334.0
HKD2_k127_4203624_22 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 313.0
HKD2_k127_4203624_23 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000542 320.0
HKD2_k127_4203624_24 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 309.0
HKD2_k127_4203624_25 FAD dependent oxidoreductase K00273 - 1.4.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 319.0
HKD2_k127_4203624_26 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 302.0
HKD2_k127_4203624_27 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007976 293.0
HKD2_k127_4203624_28 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000001582 252.0
HKD2_k127_4203624_29 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000001041 241.0
HKD2_k127_4203624_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 566.0
HKD2_k127_4203624_30 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008193 252.0
HKD2_k127_4203624_31 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000001477 229.0
HKD2_k127_4203624_32 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000001756 237.0
HKD2_k127_4203624_33 WYL domain K13572 - - 0.000000000000000000000000000000000000000000000000000000000008289 235.0
HKD2_k127_4203624_34 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000003413 207.0
HKD2_k127_4203624_35 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000001944 224.0
HKD2_k127_4203624_36 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001377 201.0
HKD2_k127_4203624_37 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000006051 222.0
HKD2_k127_4203624_38 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000006971 214.0
HKD2_k127_4203624_39 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.00000000000000000000000000000000000000000000000001359 199.0
HKD2_k127_4203624_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 556.0
HKD2_k127_4203624_40 pfam ammecr1 K09141 - - 0.00000000000000000000000000000000000000000000000004231 188.0
HKD2_k127_4203624_41 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000005197 182.0
HKD2_k127_4203624_42 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000001461 181.0
HKD2_k127_4203624_43 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000002526 191.0
HKD2_k127_4203624_44 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619 - 1.20.4.1,2.3.1.1 0.000000000000000000000000000000000000005019 161.0
HKD2_k127_4203624_45 protoporphyrinogen oxidase activity K00231,K00274 - 1.3.3.15,1.3.3.4,1.4.3.4 0.000000000000000000000000000000000003267 158.0
HKD2_k127_4203624_46 Ferredoxin - - - 0.000000000000000000000000000000000004322 157.0
HKD2_k127_4203624_47 dioxygenase activity K10674,K21195 - 1.14.11.46,1.14.11.55 0.0000000000000000000000000000000001755 151.0
HKD2_k127_4203624_48 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001175 118.0
HKD2_k127_4203624_49 Subtilase family K14743 - - 0.00000000000000000000000002625 125.0
HKD2_k127_4203624_5 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 528.0
HKD2_k127_4203624_50 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000009543 112.0
HKD2_k127_4203624_51 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000005117 91.0
HKD2_k127_4203624_52 HxlR-like helix-turn-helix - - - 0.0000000000000006303 87.0
HKD2_k127_4203624_53 PPIC-type PPIASE domain - - - 0.0000009291 62.0
HKD2_k127_4203624_54 Putative zinc-finger - - - 0.00001166 57.0
HKD2_k127_4203624_56 Cell division protein FtsQ K03589 - - 0.0003938 53.0
HKD2_k127_4203624_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 522.0
HKD2_k127_4203624_7 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 488.0
HKD2_k127_4203624_8 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 485.0
HKD2_k127_4203624_9 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 487.0
HKD2_k127_4227845_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.336e-217 704.0
HKD2_k127_4227845_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 447.0
HKD2_k127_4227845_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000002006 226.0
HKD2_k127_4227845_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000003889 211.0
HKD2_k127_4227845_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000007008 201.0
HKD2_k127_4227845_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000004274 151.0
HKD2_k127_4227845_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000005662 93.0
HKD2_k127_4227845_7 - - - - 0.00000008098 59.0
HKD2_k127_4227845_8 - - - - 0.000001539 60.0
HKD2_k127_4233811_0 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.0 1808.0
HKD2_k127_4233811_1 Glucose / Sorbosone dehydrogenase - - - 9.805e-306 976.0
HKD2_k127_4233811_10 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000003328 155.0
HKD2_k127_4233811_11 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000358 128.0
HKD2_k127_4233811_12 Serine aminopeptidase, S33 K06889 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009605,GO:0009607,GO:0030312,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.0000000000002711 81.0
HKD2_k127_4233811_13 4'-phosphopantetheinyl transferase superfamily - - - 0.00000000291 61.0
HKD2_k127_4233811_14 Glyoxalase-like domain - - - 0.0000008829 59.0
HKD2_k127_4233811_2 Amino acid adenylation domain - - - 5.73e-281 923.0
HKD2_k127_4233811_3 Acyl transferase domain in polyketide synthase (PKS) enzymes. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 521.0
HKD2_k127_4233811_4 ATPase (AAA K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 441.0
HKD2_k127_4233811_5 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 402.0
HKD2_k127_4233811_6 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001112 296.0
HKD2_k127_4233811_7 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002573 283.0
HKD2_k127_4233811_8 PFAM Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 271.0
HKD2_k127_4233811_9 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000001333 153.0
HKD2_k127_4239949_0 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 549.0
HKD2_k127_4239949_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 465.0
HKD2_k127_4239949_10 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000002308 176.0
HKD2_k127_4239949_11 PFAM peptidase S49 K04773,K04774 - - 0.0000000000000000000000000000000000000000002412 169.0
HKD2_k127_4239949_12 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000004138 166.0
HKD2_k127_4239949_13 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000168 177.0
HKD2_k127_4239949_14 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000008253 168.0
HKD2_k127_4239949_15 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000008612 164.0
HKD2_k127_4239949_16 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000001552 160.0
HKD2_k127_4239949_17 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000003199 143.0
HKD2_k127_4239949_18 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000003431 133.0
HKD2_k127_4239949_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 391.0
HKD2_k127_4239949_20 Biotin-requiring enzyme - - - 0.000000000000000001933 87.0
HKD2_k127_4239949_21 Belongs to the Nudix hydrolase family - - - 0.00000000003165 76.0
HKD2_k127_4239949_22 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000004021 70.0
HKD2_k127_4239949_23 Gcn5-related n-acetyltransferase K06976 - - 0.000000002539 69.0
HKD2_k127_4239949_24 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.000008236 59.0
HKD2_k127_4239949_25 Cytochrome c - - - 0.0001244 56.0
HKD2_k127_4239949_26 - - - - 0.0003737 55.0
HKD2_k127_4239949_3 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 366.0
HKD2_k127_4239949_4 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 377.0
HKD2_k127_4239949_5 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 338.0
HKD2_k127_4239949_6 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 315.0
HKD2_k127_4239949_7 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 292.0
HKD2_k127_4239949_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 299.0
HKD2_k127_4239949_9 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000001328 237.0
HKD2_k127_4303674_0 ABC transporter transmembrane region K06148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 590.0
HKD2_k127_4303674_1 to Mus musculus sphingosine-1-phosphate lyase Sgpl1 SWALL O54955 (EMBL AF036894) (568 aa) fasta scores E() K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 553.0
HKD2_k127_4303674_10 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 363.0
HKD2_k127_4303674_11 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 349.0
HKD2_k127_4303674_12 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 324.0
HKD2_k127_4303674_13 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 336.0
HKD2_k127_4303674_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 294.0
HKD2_k127_4303674_15 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001146 302.0
HKD2_k127_4303674_16 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000584 292.0
HKD2_k127_4303674_17 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002322 280.0
HKD2_k127_4303674_18 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009728 261.0
HKD2_k127_4303674_19 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005139 232.0
HKD2_k127_4303674_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 510.0
HKD2_k127_4303674_20 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000004611 239.0
HKD2_k127_4303674_21 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000008066 222.0
HKD2_k127_4303674_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000009295 211.0
HKD2_k127_4303674_23 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000006143 197.0
HKD2_k127_4303674_24 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000002982 180.0
HKD2_k127_4303674_25 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000005736 158.0
HKD2_k127_4303674_26 PAP2 superfamily - - - 0.0000000000000000000000000000000000000006863 163.0
HKD2_k127_4303674_27 - - - - 0.000000000000000000000000000000001939 150.0
HKD2_k127_4303674_28 phage shock protein A, PspA K03969 - - 0.00000000000000000000000000000194 138.0
HKD2_k127_4303674_29 Histidine kinase - - - 0.00000000000000000000000000001216 134.0
HKD2_k127_4303674_3 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 419.0
HKD2_k127_4303674_30 lipolytic protein G-D-S-L family - - - 0.0000007441 61.0
HKD2_k127_4303674_4 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 424.0
HKD2_k127_4303674_5 glycosyl transferase family 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 426.0
HKD2_k127_4303674_6 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 403.0
HKD2_k127_4303674_7 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 393.0
HKD2_k127_4303674_8 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 377.0
HKD2_k127_4303674_9 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 366.0
HKD2_k127_4340752_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1356.0
HKD2_k127_4340752_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 9.765e-247 798.0
HKD2_k127_4340752_10 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01576,K01652 - 2.2.1.6,4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 502.0
HKD2_k127_4340752_11 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 531.0
HKD2_k127_4340752_12 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 514.0
HKD2_k127_4340752_13 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 497.0
HKD2_k127_4340752_14 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 477.0
HKD2_k127_4340752_15 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 447.0
HKD2_k127_4340752_16 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 413.0
HKD2_k127_4340752_17 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 398.0
HKD2_k127_4340752_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 370.0
HKD2_k127_4340752_19 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
HKD2_k127_4340752_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.886e-235 754.0
HKD2_k127_4340752_20 cytochrome P450 K15981 - 1.14.13.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 351.0
HKD2_k127_4340752_21 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001464 293.0
HKD2_k127_4340752_22 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000006933 273.0
HKD2_k127_4340752_23 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000002858 257.0
HKD2_k127_4340752_24 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000006106 237.0
HKD2_k127_4340752_25 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000008078 228.0
HKD2_k127_4340752_26 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000002626 214.0
HKD2_k127_4340752_27 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000002602 222.0
HKD2_k127_4340752_28 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000771 209.0
HKD2_k127_4340752_29 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000001248 196.0
HKD2_k127_4340752_3 Protein of unknown function (DUF3604) - - - 5.353e-225 719.0
HKD2_k127_4340752_30 Peptidase C26 - - - 0.0000000000000000000000000000000000000000000000002262 200.0
HKD2_k127_4340752_31 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000000004892 169.0
HKD2_k127_4340752_32 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000001824 164.0
HKD2_k127_4340752_33 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000002684 156.0
HKD2_k127_4340752_34 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000003108 146.0
HKD2_k127_4340752_35 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000001537 119.0
HKD2_k127_4340752_36 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000009969 115.0
HKD2_k127_4340752_37 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000007626 111.0
HKD2_k127_4340752_38 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000002584 98.0
HKD2_k127_4340752_39 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000002669 97.0
HKD2_k127_4340752_4 Translation-initiation factor 2 K02519 - - 2.75e-207 674.0
HKD2_k127_4340752_40 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000001181 100.0
HKD2_k127_4340752_41 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000009972 87.0
HKD2_k127_4340752_42 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000001667 90.0
HKD2_k127_4340752_43 Protein of unknown function (DUF503) K09764 - - 0.0000000000004468 83.0
HKD2_k127_4340752_44 Domain of unknown function (DUF4388) - - - 0.000000000001517 80.0
HKD2_k127_4340752_45 - - - - 0.0000000001857 73.0
HKD2_k127_4340752_46 - - - - 0.0000000253 66.0
HKD2_k127_4340752_47 Copper binding periplasmic protein CusF - - - 0.00001198 60.0
HKD2_k127_4340752_48 - - - - 0.0002298 52.0
HKD2_k127_4340752_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.109e-202 643.0
HKD2_k127_4340752_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 572.0
HKD2_k127_4340752_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 565.0
HKD2_k127_4340752_8 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 522.0
HKD2_k127_4340752_9 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 535.0
HKD2_k127_4383904_0 Ultra-violet resistance protein B K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 608.0
HKD2_k127_4383904_1 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 526.0
HKD2_k127_4383904_10 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 309.0
HKD2_k127_4383904_11 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003093 267.0
HKD2_k127_4383904_12 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001878 258.0
HKD2_k127_4383904_13 exporters of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001926 250.0
HKD2_k127_4383904_14 KR domain K18337 - 1.1.1.173,1.1.1.377,1.1.1.378 0.00000000000000000000000000000000000000000000000000000000000000007093 236.0
HKD2_k127_4383904_15 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000001919 221.0
HKD2_k127_4383904_16 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000118 220.0
HKD2_k127_4383904_17 sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000001122 198.0
HKD2_k127_4383904_18 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000007544 189.0
HKD2_k127_4383904_19 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000001979 192.0
HKD2_k127_4383904_2 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 510.0
HKD2_k127_4383904_20 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000003024 193.0
HKD2_k127_4383904_21 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000003758 160.0
HKD2_k127_4383904_22 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000001723 162.0
HKD2_k127_4383904_23 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000002503 161.0
HKD2_k127_4383904_24 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.000000000000000000000000000000000001414 155.0
HKD2_k127_4383904_25 DoxX-like family - - - 0.000000000000000000000000000000001788 149.0
HKD2_k127_4383904_26 EamA-like transporter family - - - 0.000000000000000000000000000000003028 140.0
HKD2_k127_4383904_27 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000002276 140.0
HKD2_k127_4383904_28 Polymer-forming cytoskeletal - - - 0.000000000000000000000003687 113.0
HKD2_k127_4383904_29 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000002148 98.0
HKD2_k127_4383904_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 497.0
HKD2_k127_4383904_30 PTS HPr component phosphorylation site K11189 - - 0.0000000000006545 78.0
HKD2_k127_4383904_31 protein conserved in bacteria K09774 - - 0.00006867 56.0
HKD2_k127_4383904_4 Amidase K01426,K19176 - 3.5.1.4,3.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 400.0
HKD2_k127_4383904_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 386.0
HKD2_k127_4383904_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 390.0
HKD2_k127_4383904_7 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 368.0
HKD2_k127_4383904_8 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 346.0
HKD2_k127_4383904_9 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 321.0
HKD2_k127_4523722_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 569.0
HKD2_k127_4523722_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 445.0
HKD2_k127_4523722_10 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000007929 197.0
HKD2_k127_4523722_11 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000004504 193.0
HKD2_k127_4523722_12 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000002544 158.0
HKD2_k127_4523722_13 acetyltransferase - - - 0.000000000000000000000000000000008038 137.0
HKD2_k127_4523722_14 Pfam:DUF385 - - - 0.0000000000003006 76.0
HKD2_k127_4523722_15 Sh3 type 3 domain protein - - - 0.0000000000004392 84.0
HKD2_k127_4523722_16 Protein of unknown function (DUF1302) - - - 0.00000000003603 78.0
HKD2_k127_4523722_17 Bacterial regulatory proteins, tetR family - - - 0.000000004287 66.0
HKD2_k127_4523722_18 YfdX protein - - - 0.00007561 54.0
HKD2_k127_4523722_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 442.0
HKD2_k127_4523722_3 carboxylic ester hydrolase activity K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 426.0
HKD2_k127_4523722_4 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 325.0
HKD2_k127_4523722_5 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000687 286.0
HKD2_k127_4523722_6 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001821 281.0
HKD2_k127_4523722_7 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001196 277.0
HKD2_k127_4523722_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003912 252.0
HKD2_k127_4523722_9 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001275 219.0
HKD2_k127_4750564_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1482.0
HKD2_k127_4750564_1 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1197.0
HKD2_k127_4750564_10 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 475.0
HKD2_k127_4750564_11 Catalyzes the desulfonation of aliphatic sulfonates K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 482.0
HKD2_k127_4750564_12 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 418.0
HKD2_k127_4750564_13 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 458.0
HKD2_k127_4750564_14 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 428.0
HKD2_k127_4750564_15 UTP--glucose-1-phosphate uridylyltransferase K00972,K12447 - 2.7.7.23,2.7.7.64,2.7.7.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 380.0
HKD2_k127_4750564_16 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 385.0
HKD2_k127_4750564_17 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 374.0
HKD2_k127_4750564_18 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 362.0
HKD2_k127_4750564_19 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 370.0
HKD2_k127_4750564_2 Phosphoglucose isomerase K01810 - 5.3.1.9 1.339e-282 881.0
HKD2_k127_4750564_20 ABC transporter K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 343.0
HKD2_k127_4750564_21 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 351.0
HKD2_k127_4750564_22 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 342.0
HKD2_k127_4750564_23 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 358.0
HKD2_k127_4750564_24 Predicted permease K07089,K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 342.0
HKD2_k127_4750564_25 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 311.0
HKD2_k127_4750564_26 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001137 296.0
HKD2_k127_4750564_27 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000001957 273.0
HKD2_k127_4750564_28 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006943 279.0
HKD2_k127_4750564_29 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 261.0
HKD2_k127_4750564_3 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 5.132e-276 877.0
HKD2_k127_4750564_30 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000004849 278.0
HKD2_k127_4750564_31 PFAM phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009539 278.0
HKD2_k127_4750564_32 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004787 252.0
HKD2_k127_4750564_33 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000001833 254.0
HKD2_k127_4750564_34 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000108 235.0
HKD2_k127_4750564_35 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000001103 223.0
HKD2_k127_4750564_36 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000002029 220.0
HKD2_k127_4750564_37 ATPase component of Mn Zn ABC-type transporter K09817,K09820 - - 0.00000000000000000000000000000000000000000000000000000000001284 218.0
HKD2_k127_4750564_38 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000001473 222.0
HKD2_k127_4750564_39 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000006738 209.0
HKD2_k127_4750564_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 4.348e-275 855.0
HKD2_k127_4750564_40 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000001318 211.0
HKD2_k127_4750564_41 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.000000000000000000000000000000000000000000000000000000002359 220.0
HKD2_k127_4750564_42 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000002822 209.0
HKD2_k127_4750564_43 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000003931 200.0
HKD2_k127_4750564_44 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.0000000000000000000000000000000000000000000000006639 196.0
HKD2_k127_4750564_45 very-long-chain-acyl-CoA dehydrogenase activity K00249,K11729 GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016627,GO:0019395,GO:0019752,GO:0030258,GO:0031974,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.8.7 0.000000000000000000000000000000000000000000000008858 179.0
HKD2_k127_4750564_46 EthD domain - - - 0.00000000000000000000000000000000000000000000001351 179.0
HKD2_k127_4750564_47 transglycosylase K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000003162 193.0
HKD2_k127_4750564_48 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000004296 190.0
HKD2_k127_4750564_49 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.000000000000000000000000000000000000000000005016 188.0
HKD2_k127_4750564_5 Sulfatase - - - 2.276e-230 723.0
HKD2_k127_4750564_50 response regulator K07715 - - 0.0000000000000000000000000000000000000000009299 171.0
HKD2_k127_4750564_51 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000006519 171.0
HKD2_k127_4750564_52 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.0000000000000000000000000000000000005645 161.0
HKD2_k127_4750564_53 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000361 149.0
HKD2_k127_4750564_54 Phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000000000000003379 148.0
HKD2_k127_4750564_55 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000003793 145.0
HKD2_k127_4750564_56 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000002055 119.0
HKD2_k127_4750564_57 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000004629 117.0
HKD2_k127_4750564_58 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000002175 126.0
HKD2_k127_4750564_59 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000002303 126.0
HKD2_k127_4750564_6 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 1.558e-204 662.0
HKD2_k127_4750564_60 response regulator - - - 0.0000000000000000001521 103.0
HKD2_k127_4750564_61 Ribosomal protein L31 K02909 - - 0.0000000000000000003134 93.0
HKD2_k127_4750564_62 - - - - 0.000000000000000002379 98.0
HKD2_k127_4750564_63 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000002551 87.0
HKD2_k127_4750564_64 Universal stress protein family - - - 0.0000000000000004144 93.0
HKD2_k127_4750564_65 HAD-hyrolase-like K01560,K07025,K08723,K20862 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006206,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008655,GO:0009058,GO:0009112,GO:0009410,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019856,GO:0019859,GO:0030145,GO:0034641,GO:0034654,GO:0042221,GO:0042578,GO:0043094,GO:0043100,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104,3.1.3.5,3.8.1.2 0.0000000000001521 80.0
HKD2_k127_4750564_66 Forkhead associated domain - - - 0.0000000000004103 76.0
HKD2_k127_4750564_67 Protein of unknown function (FYDLN_acid) - - - 0.0000000001409 75.0
HKD2_k127_4750564_68 Transcriptional regulator, TetR family - - - 0.000000007179 66.0
HKD2_k127_4750564_69 belongs to the thioredoxin family K03619,K05838 - - 0.00001235 59.0
HKD2_k127_4750564_7 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 535.0
HKD2_k127_4750564_70 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.0002621 53.0
HKD2_k127_4750564_8 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 530.0
HKD2_k127_4750564_9 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 507.0
HKD2_k127_4866164_0 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 5.459e-228 723.0
HKD2_k127_4866164_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 599.0
HKD2_k127_4866164_10 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000919 226.0
HKD2_k127_4866164_11 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000000000006917 187.0
HKD2_k127_4866164_12 PFAM Zn-finger in ubiquitin-hydrolases and other protein - - - 0.000000000000000000000000000000000000000001761 163.0
HKD2_k127_4866164_13 - - - - 0.000000000000000000000000000000000000000005506 173.0
HKD2_k127_4866164_14 YjbR - - - 0.00000000000000000000000000000000002608 156.0
HKD2_k127_4866164_15 Phosphopantetheine attachment site - - - 0.0000000000009138 79.0
HKD2_k127_4866164_16 Bacterial SH3 domain - - - 0.000000000005397 80.0
HKD2_k127_4866164_2 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 539.0
HKD2_k127_4866164_3 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 455.0
HKD2_k127_4866164_4 Aminotransferase class-III K12256 - 2.6.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 446.0
HKD2_k127_4866164_5 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 396.0
HKD2_k127_4866164_6 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 367.0
HKD2_k127_4866164_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 309.0
HKD2_k127_4866164_8 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001661 271.0
HKD2_k127_4866164_9 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000002398 253.0
HKD2_k127_4924202_0 alcohol dehydrogenase K00117 - 1.1.5.2 1.903e-194 628.0
HKD2_k127_4924202_1 cytochrome p450 K16046 - 1.14.13.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 453.0
HKD2_k127_4924202_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 322.0
HKD2_k127_4924202_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000002226 254.0
HKD2_k127_4924202_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000008931 172.0
HKD2_k127_4924202_5 FMN_bind - - - 0.0000000000000000000000000000000000000002499 158.0
HKD2_k127_4924202_6 - - - - 0.000000000000000000000000000000007197 143.0
HKD2_k127_4924202_7 transcriptional regulator - - - 0.00000000000000000000000000003789 126.0
HKD2_k127_499159_0 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 552.0
HKD2_k127_499159_1 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 358.0
HKD2_k127_499159_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004662 282.0
HKD2_k127_499159_3 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000002754 238.0
HKD2_k127_499159_4 Belongs to the universal stress protein A family - - - 0.00000000002236 78.0
HKD2_k127_5052223_0 Glucose dehydrogenase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 388.0
HKD2_k127_5052223_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 331.0
HKD2_k127_5052223_10 Fungal chitosanase of glycosyl hydrolase group 75 - - - 0.000000000000000000000000000000000000000004347 164.0
HKD2_k127_5052223_11 MAPEG family - - - 0.00000000000000000000000000001159 125.0
HKD2_k127_5052223_12 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000002374 126.0
HKD2_k127_5052223_13 Cytochrome c - - - 0.000000000000000000001063 107.0
HKD2_k127_5052223_14 Methylamine utilisation protein MauE - - - 0.0000000000000000002115 96.0
HKD2_k127_5052223_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000001016 62.0
HKD2_k127_5052223_16 Recombinase zinc beta ribbon domain K06400 - - 0.000002504 56.0
HKD2_k127_5052223_17 SnoaL-like domain - - - 0.00001309 53.0
HKD2_k127_5052223_18 Resolvase, N terminal domain - - - 0.0001641 53.0
HKD2_k127_5052223_19 Amidohydrolase family - - - 0.0005446 45.0
HKD2_k127_5052223_2 SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 321.0
HKD2_k127_5052223_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001183 263.0
HKD2_k127_5052223_4 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002543 280.0
HKD2_k127_5052223_5 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000008102 251.0
HKD2_k127_5052223_6 Methylamine dehydrogenase light chain K15228 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000003214 222.0
HKD2_k127_5052223_7 methylamine dehydrogenase accessory protein MauD - - - 0.0000000000000000000000000000000000000000000000000000008101 207.0
HKD2_k127_5052223_8 MarR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000005197 179.0
HKD2_k127_5052223_9 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000001465 188.0
HKD2_k127_5167234_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 6.508e-200 633.0
HKD2_k127_5167234_1 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 519.0
HKD2_k127_5167234_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 514.0
HKD2_k127_5167234_3 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 343.0
HKD2_k127_5167234_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 320.0
HKD2_k127_5167234_5 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000002799 213.0
HKD2_k127_5167234_6 Cytochrome c - - - 0.000000000001184 81.0
HKD2_k127_5167234_7 PFAM S-layer homology domain - - - 0.0002859 50.0
HKD2_k127_5250422_0 GTP-binding protein TypA K06207 - - 6.062e-217 689.0
HKD2_k127_5250422_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 499.0
HKD2_k127_5250422_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000005242 71.0
HKD2_k127_5250422_11 Alpha/beta hydrolase family - - - 0.000169 53.0
HKD2_k127_5250422_12 GDSL-like Lipase/Acylhydrolase family - - - 0.0001869 55.0
HKD2_k127_5250422_2 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 316.0
HKD2_k127_5250422_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000001035 249.0
HKD2_k127_5250422_4 PFAM Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000003556 237.0
HKD2_k127_5250422_5 Cytochrome P450 K20497 - 1.14.15.14 0.00000000000000000000000000000000000000000000000000000001358 202.0
HKD2_k127_5250422_6 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000124 142.0
HKD2_k127_5250422_8 - - - - 0.000000000000000000000002811 118.0
HKD2_k127_5250422_9 Serine aminopeptidase, S33 - - - 0.00000000002077 74.0
HKD2_k127_5254_0 breast cancer carboxy-terminal domain K01972 - 6.5.1.2 1.209e-198 663.0
HKD2_k127_5254_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 540.0
HKD2_k127_5254_10 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000002848 147.0
HKD2_k127_5254_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000000004048 150.0
HKD2_k127_5254_12 PFAM ABC transporter related K02065 - - 0.0000000000000000000000000000000009851 138.0
HKD2_k127_5254_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000003438 121.0
HKD2_k127_5254_14 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003366 100.0
HKD2_k127_5254_15 ig-like, plexins, transcription factors - - - 0.000000000000000000001292 111.0
HKD2_k127_5254_16 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000003472 91.0
HKD2_k127_5254_17 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000004651 94.0
HKD2_k127_5254_18 oligosaccharyl transferase activity - - - 0.00000000000009496 85.0
HKD2_k127_5254_19 Belongs to the UPF0102 family K07460 - - 0.0000000001673 71.0
HKD2_k127_5254_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 421.0
HKD2_k127_5254_20 Protein of unknown function (DUF721) - - - 0.0000001723 64.0
HKD2_k127_5254_21 Belongs to the UPF0109 family K06960 - - 0.000001305 57.0
HKD2_k127_5254_22 Pectate lyase K01728 - 4.2.2.2 0.0003775 52.0
HKD2_k127_5254_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 404.0
HKD2_k127_5254_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001926 301.0
HKD2_k127_5254_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000003461 261.0
HKD2_k127_5254_6 isomerase K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001099 251.0
HKD2_k127_5254_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
HKD2_k127_5254_8 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000006737 238.0
HKD2_k127_5254_9 PFAM Heparinase II - - - 0.00000000000000000000000000000000000000000000000000000002032 221.0
HKD2_k127_527083_0 CobN magnesium chelatase K03403 - 6.6.1.1 0.0 1657.0
HKD2_k127_527083_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 5.12e-306 950.0
HKD2_k127_527083_10 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 7.821e-202 670.0
HKD2_k127_527083_11 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 7.06e-199 635.0
HKD2_k127_527083_12 formyl-CoA transferase activity K14470 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015977,GO:0016853,GO:0016866,GO:0016867,GO:0043427,GO:0071704 5.4.1.3 3.86e-197 625.0
HKD2_k127_527083_13 Photosynthetic complex (LH1) assembly protein LhaA K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 617.0
HKD2_k127_527083_14 The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis K08929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 578.0
HKD2_k127_527083_15 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 591.0
HKD2_k127_527083_16 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 599.0
HKD2_k127_527083_17 Belongs to the NifH BchL ChlL family K11333 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 563.0
HKD2_k127_527083_18 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 531.0
HKD2_k127_527083_19 Fructose-1-6-bisphosphatase, N-terminal domain K01086 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 535.0
HKD2_k127_527083_2 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 1.471e-274 849.0
HKD2_k127_527083_20 Photosynthetic reaction center L subunit K08928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 523.0
HKD2_k127_527083_21 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 519.0
HKD2_k127_527083_22 Magnesium chelatase, subunit ChlI K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 518.0
HKD2_k127_527083_23 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 488.0
HKD2_k127_527083_24 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 479.0
HKD2_k127_527083_25 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 512.0
HKD2_k127_527083_26 PUCC protein K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 467.0
HKD2_k127_527083_27 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 437.0
HKD2_k127_527083_28 PFAM O-methyltransferase K09846 - 2.1.1.210 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 431.0
HKD2_k127_527083_29 TIGRFAM bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 416.0
HKD2_k127_527083_3 Phytochrome region - - - 1.205e-264 855.0
HKD2_k127_527083_30 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 400.0
HKD2_k127_527083_31 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 371.0
HKD2_k127_527083_32 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 379.0
HKD2_k127_527083_33 Dehydratase K18290 - 4.2.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 373.0
HKD2_k127_527083_34 magnesium chelatase accessory protein K06049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 331.0
HKD2_k127_527083_35 PFAM hydroxyneurosporene synthase K09844 - 4.2.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 340.0
HKD2_k127_527083_36 Protein of unknown function (DUF3623) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 306.0
HKD2_k127_527083_37 Transcriptional regulator, LysR K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 299.0
HKD2_k127_527083_38 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 - 2.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 311.0
HKD2_k127_527083_39 Peptidase dimerisation domain K12941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 304.0
HKD2_k127_527083_4 Proto-chlorophyllide reductase 57 kD subunit K11335 - 1.3.7.14,1.3.7.15 1.27e-250 806.0
HKD2_k127_527083_40 Photosynthetic reaction centre, H-chain N-terminal region K13991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 308.0
HKD2_k127_527083_41 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000246 278.0
HKD2_k127_527083_42 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000002616 267.0
HKD2_k127_527083_43 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000004398 230.0
HKD2_k127_527083_44 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000005729 239.0
HKD2_k127_527083_45 2-vinyl bacteriochlorophyllide hydratase (BCHF) K11336 - 4.2.1.165 0.0000000000000000000000000000000000000000000000000000000000006514 214.0
HKD2_k127_527083_46 ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000006701 227.0
HKD2_k127_527083_47 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000000012 211.0
HKD2_k127_527083_48 HpcH/HpaI aldolase/citrate lyase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000004749 214.0
HKD2_k127_527083_49 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000002934 193.0
HKD2_k127_527083_5 Chlorophyllide reductase subunit Y K11334 - 1.3.7.14,1.3.7.15 3.789e-239 749.0
HKD2_k127_527083_50 B12-binding - - - 0.00000000000000000000000000000000000000000000000001181 194.0
HKD2_k127_527083_51 Heme oxygenase K21480 - 1.14.15.20 0.0000000000000000000000000000000000000000000000001398 191.0
HKD2_k127_527083_52 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000007216 175.0
HKD2_k127_527083_53 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000003618 175.0
HKD2_k127_527083_54 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000001174 183.0
HKD2_k127_527083_55 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000467 154.0
HKD2_k127_527083_56 Photosynthetic complex assembly protein - - - 0.00000000000000000000000000000002119 134.0
HKD2_k127_527083_57 NUDIX domain - - - 0.00000000000000000000000000000002637 131.0
HKD2_k127_527083_58 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000004858 142.0
HKD2_k127_527083_59 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000003902 139.0
HKD2_k127_527083_6 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 1.919e-220 711.0
HKD2_k127_527083_60 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000003229 123.0
HKD2_k127_527083_61 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000005498 120.0
HKD2_k127_527083_62 helix_turn_helix, mercury resistance - - - 0.00000000000000000000001486 106.0
HKD2_k127_527083_63 PFAM CBS domain containing protein - - - 0.00000000000000000000004942 113.0
HKD2_k127_527083_64 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08926 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000347 91.0
HKD2_k127_527083_65 - - - - 0.000000000000000000246 97.0
HKD2_k127_527083_66 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000000000002645 97.0
HKD2_k127_527083_68 Ceramidase - - - 0.0000000000000223 82.0
HKD2_k127_527083_69 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000005635 79.0
HKD2_k127_527083_7 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.222e-209 670.0
HKD2_k127_527083_70 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000009367 76.0
HKD2_k127_527083_71 alcohol dehydrogenase - - - 0.000000004255 68.0
HKD2_k127_527083_72 Psort location Cytoplasmic, score - - - 0.00000003244 67.0
HKD2_k127_527083_74 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0003037 48.0
HKD2_k127_527083_75 Dehydrogenase K00004,K00008,K00060,K08322 GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0030246,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 1.1.1.103,1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4 0.0005008 51.0
HKD2_k127_527083_8 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 5.671e-206 651.0
HKD2_k127_527083_9 Flavin containing amine oxidoreductase K09845 - 1.3.99.27 7.47e-202 640.0
HKD2_k127_5325766_0 DEAD DEAH box helicase K06877 - - 1.102e-276 893.0
HKD2_k127_5325766_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.063e-246 787.0
HKD2_k127_5325766_10 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 308.0
HKD2_k127_5325766_11 SGNH hydrolase-like domain, acetyltransferase AlgX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003152 259.0
HKD2_k127_5325766_12 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000001844 209.0
HKD2_k127_5325766_13 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000002596 182.0
HKD2_k127_5325766_14 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000003321 192.0
HKD2_k127_5325766_15 Glycosyl transferase, family 2 K00712 - 2.4.1.52 0.0000000000000000000000000000000000000001793 155.0
HKD2_k127_5325766_16 methyltransferase - - - 0.00000000000000000000000000000000000003546 157.0
HKD2_k127_5325766_17 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000001167 149.0
HKD2_k127_5325766_18 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.00000000000000000000121 108.0
HKD2_k127_5325766_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 520.0
HKD2_k127_5325766_20 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000001014 71.0
HKD2_k127_5325766_21 - - - - 0.0001392 51.0
HKD2_k127_5325766_3 ATP-binding protein K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 460.0
HKD2_k127_5325766_4 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 453.0
HKD2_k127_5325766_5 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 459.0
HKD2_k127_5325766_6 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 379.0
HKD2_k127_5325766_7 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 386.0
HKD2_k127_5325766_8 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 379.0
HKD2_k127_5325766_9 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 369.0
HKD2_k127_5336590_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 633.0
HKD2_k127_5336590_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 635.0
HKD2_k127_5336590_10 Protein of unknown function (DUF952) K09705 - - 0.00000000003329 74.0
HKD2_k127_5336590_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 574.0
HKD2_k127_5336590_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 559.0
HKD2_k127_5336590_4 PFAM ABC transporter K02471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 502.0
HKD2_k127_5336590_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 417.0
HKD2_k127_5336590_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 355.0
HKD2_k127_5336590_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 346.0
HKD2_k127_5336590_8 Lactoylglutathione lyase - - - 0.0000000000000000000000000000000000000000003139 165.0
HKD2_k127_5336590_9 Methyltransferase type 11 - - - 0.00000000000000000000000001288 127.0
HKD2_k127_5341782_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1461.0
HKD2_k127_5341782_1 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1150.0
HKD2_k127_5341782_10 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 412.0
HKD2_k127_5341782_11 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 374.0
HKD2_k127_5341782_12 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 375.0
HKD2_k127_5341782_13 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 340.0
HKD2_k127_5341782_14 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 363.0
HKD2_k127_5341782_15 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 347.0
HKD2_k127_5341782_16 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 349.0
HKD2_k127_5341782_17 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 331.0
HKD2_k127_5341782_18 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 358.0
HKD2_k127_5341782_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 302.0
HKD2_k127_5341782_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.384e-268 889.0
HKD2_k127_5341782_20 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 302.0
HKD2_k127_5341782_21 4Fe-4S binding domain K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005707 294.0
HKD2_k127_5341782_22 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 274.0
HKD2_k127_5341782_23 lipoprotein involved in nitrous oxide reduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000314 248.0
HKD2_k127_5341782_24 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000004821 242.0
HKD2_k127_5341782_25 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000004523 162.0
HKD2_k127_5341782_26 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000001097 175.0
HKD2_k127_5341782_27 Transcriptional regulator - - - 0.0000000000000000000000000000000001248 141.0
HKD2_k127_5341782_28 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000006843 127.0
HKD2_k127_5341782_29 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000003061 124.0
HKD2_k127_5341782_3 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 576.0
HKD2_k127_5341782_30 NosL - - - 0.000000000000000000000000846 118.0
HKD2_k127_5341782_31 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000001677 104.0
HKD2_k127_5341782_32 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000001138 103.0
HKD2_k127_5341782_33 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000006295 103.0
HKD2_k127_5341782_34 Pentapeptide - - - 0.00000000000000003172 97.0
HKD2_k127_5341782_35 Flavodoxin domain - - - 0.000000000000004956 85.0
HKD2_k127_5341782_36 Major facilitator superfamily - - - 0.000005961 59.0
HKD2_k127_5341782_4 cytochrome P450 K05917 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008398,GO:0016125,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0032451,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046906,GO:0048037,GO:0055114,GO:0070988,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901615 1.14.13.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 449.0
HKD2_k127_5341782_5 Nitrous oxidase accessory protein K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 443.0
HKD2_k127_5341782_6 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 408.0
HKD2_k127_5341782_7 4Fe-4S binding domain K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000592 422.0
HKD2_k127_5341782_8 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 403.0
HKD2_k127_5341782_9 COG1062 Zn-dependent alcohol dehydrogenases, class III K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 398.0
HKD2_k127_5386210_0 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 441.0
HKD2_k127_5386210_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 312.0
HKD2_k127_5386210_10 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.0000000000000000334 95.0
HKD2_k127_5386210_11 repeat protein - - - 0.000000000003404 81.0
HKD2_k127_5386210_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000006287 243.0
HKD2_k127_5386210_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000003632 200.0
HKD2_k127_5386210_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000001941 186.0
HKD2_k127_5386210_5 repeat protein - - - 0.0000000000000000000000000000000000000000000007189 191.0
HKD2_k127_5386210_6 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000005968 170.0
HKD2_k127_5386210_7 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000008769 139.0
HKD2_k127_5386210_8 - K01992 - - 0.000000000000000000000000000000000916 151.0
HKD2_k127_5386210_9 Biopolymer transport protein K03559 - - 0.000000000000000002994 91.0
HKD2_k127_5429537_0 Amidohydrolase family - - - 3.176e-197 632.0
HKD2_k127_5429537_1 oligopeptide transporter, OPT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 625.0
HKD2_k127_5429537_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.00000000000000000000001446 110.0
HKD2_k127_5429537_12 acyl-CoA dehydrogenase activity - - - 0.000004904 51.0
HKD2_k127_5429537_13 Haem-binding domain - - - 0.00006285 51.0
HKD2_k127_5429537_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 532.0
HKD2_k127_5429537_3 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 436.0
HKD2_k127_5429537_4 3-oxoacid CoA-transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 390.0
HKD2_k127_5429537_5 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 360.0
HKD2_k127_5429537_6 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 335.0
HKD2_k127_5429537_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006818 271.0
HKD2_k127_5429537_8 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000003201 218.0
HKD2_k127_5562915_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006832 227.0
HKD2_k127_5562915_1 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000006413 207.0
HKD2_k127_5562915_2 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000001257 179.0
HKD2_k127_5562915_3 DoxX - - - 0.000000000000000000000000000000000000000000000002131 196.0
HKD2_k127_5562915_4 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000001768 147.0
HKD2_k127_5562915_5 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000001502 134.0
HKD2_k127_5562915_6 RNA polymerase sigma factor, sigma-70 family K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000001422 124.0
HKD2_k127_5562915_7 Putative zinc-finger - - - 0.0000000000000000000000000003128 123.0
HKD2_k127_5562915_8 gluconolactonase activity K01053 - 3.1.1.17 0.00000000000001214 85.0
HKD2_k127_5570822_0 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 364.0
HKD2_k127_5570822_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 327.0
HKD2_k127_5570822_10 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000001801 179.0
HKD2_k127_5570822_11 Putative zinc-finger - - - 0.00000000000002406 76.0
HKD2_k127_5570822_12 Thioesterase-like superfamily K10805 - - 0.0000000000005183 75.0
HKD2_k127_5570822_13 transcriptional regulator, MerR family K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0006253 54.0
HKD2_k127_5570822_2 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002119 299.0
HKD2_k127_5570822_3 TIGRFAM alpha-L-glutamate ligase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000373 299.0
HKD2_k127_5570822_4 DnaJ C terminal domain K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009973 250.0
HKD2_k127_5570822_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000001148 239.0
HKD2_k127_5570822_6 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000004243 203.0
HKD2_k127_5570822_7 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000001782 216.0
HKD2_k127_5570822_8 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000487 183.0
HKD2_k127_5570822_9 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000001676 182.0
HKD2_k127_5578299_0 C-terminal, D2-small domain, of ClpB protein K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 597.0
HKD2_k127_5578299_1 Similarity to COG0471 Di- and tricarboxylate transporters(Evalue K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 429.0
HKD2_k127_5578299_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 382.0
HKD2_k127_5578299_3 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 332.0
HKD2_k127_5578299_4 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006999 296.0
HKD2_k127_5578299_5 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000006852 185.0
HKD2_k127_5578299_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000001165 114.0
HKD2_k127_5579436_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 564.0
HKD2_k127_5579436_1 Conserved Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 516.0
HKD2_k127_5579436_10 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000018 228.0
HKD2_k127_5579436_11 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000006447 171.0
HKD2_k127_5579436_12 Cytochrome c - - - 0.000000000000000000000000000000000000000000001442 173.0
HKD2_k127_5579436_13 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000002671 176.0
HKD2_k127_5579436_14 PFAM Fasciclin domain K19519 - - 0.000000000000000000000000000000000000000006797 166.0
HKD2_k127_5579436_15 Protein of unknown function (DUF3175) - - - 0.000000000000000000000000000005891 138.0
HKD2_k127_5579436_16 Protein of unknown function (DUF2834) - - - 0.0000000000000000000000000004019 117.0
HKD2_k127_5579436_17 Protein of unknown function (DUF2905) - - - 0.00000000000001212 78.0
HKD2_k127_5579436_18 Putative bacterial sensory transduction regulator - - - 0.00004086 55.0
HKD2_k127_5579436_19 disintegrin and metalloproteinase K06540 GO:0000323,GO:0000768,GO:0000902,GO:0001525,GO:0001568,GO:0001666,GO:0001667,GO:0001775,GO:0001817,GO:0001819,GO:0001932,GO:0001934,GO:0001944,GO:0002102,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002520,GO:0002521,GO:0002523,GO:0002573,GO:0002673,GO:0002675,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002691,GO:0002693,GO:0002694,GO:0002696,GO:0002761,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005767,GO:0005773,GO:0005856,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006935,GO:0006949,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007155,GO:0007160,GO:0007162,GO:0007275,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008237,GO:0008270,GO:0009605,GO:0009628,GO:0009653,GO:0009888,GO:0009889,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010468,GO:0010556,GO:0010562,GO:0010604,GO:0010628,GO:0010631,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010954,GO:0012505,GO:0012506,GO:0015629,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016477,GO:0016787,GO:0017171,GO:0019219,GO:0019220,GO:0019222,GO:0019538,GO:0022407,GO:0022408,GO:0022409,GO:0022411,GO:0022610,GO:0022617,GO:0023051,GO:0023056,GO:0030097,GO:0030099,GO:0030139,GO:0030141,GO:0030154,GO:0030155,GO:0030162,GO:0030198,GO:0030316,GO:0030334,GO:0030335,GO:0030595,GO:0030659,GO:0030667,GO:0031045,GO:0031090,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031329,GO:0031331,GO:0031347,GO:0031349,GO:0031399,GO:0031401,GO:0031410,GO:0031589,GO:0031982,GO:0032010,GO:0032101,GO:0032103,GO:0032127,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033081,GO:0033089,GO:0033554,GO:0033674,GO:0034103,GO:0034105,GO:0035239,GO:0035295,GO:0035579,GO:0036230,GO:0036293,GO:0036294,GO:0040011,GO:0040012,GO:0040017,GO:0042119,GO:0042176,GO:0042221,GO:0042325,GO:0042327,GO:0042330,GO:0042581,GO:0042981,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043299,GO:0043312,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043523,GO:0043524,GO:0043534,GO:0043542,GO:0043549,GO:0043621,GO:0044093,GO:0044238,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045088,GO:0045089,GO:0045124,GO:0045321,GO:0045335,GO:0045580,GO:0045582,GO:0045595,GO:0045597,GO:0045619,GO:0045621,GO:0045637,GO:0045670,GO:0045732,GO:0045780,GO:0045785,GO:0045859,GO:0045860,GO:0045862,GO:0045937,GO:0046850,GO:0046852,GO:0046872,GO:0046903,GO:0046914,GO:0048247,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048870,GO:0050708,GO:0050714,GO:0050727,GO:0050729,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0050863,GO:0050865,GO:0050867,GO:0050870,GO:0050896,GO:0050900,GO:0051043,GO:0051044,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051090,GO:0051091,GO:0051092,GO:0051094,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051249,GO:0051251,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051347,GO:0051674,GO:0051716,GO:0051896,GO:0051897,GO:0060255,GO:0060326,GO:0060548,GO:0061024,GO:0061025,GO:0065007,GO:0065008,GO:0065009,GO:0070011,GO:0070201,GO:0070228,GO:0070230,GO:0070232,GO:0070234,GO:0070243,GO:0070245,GO:0070482,GO:0070613,GO:0070820,GO:0070821,GO:0070887,GO:0071133,GO:0071453,GO:0071456,GO:0071704,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072358,GO:0072359,GO:0072674,GO:0072675,GO:0072676,GO:0080090,GO:0080134,GO:0090087,GO:0090130,GO:0090132,GO:0097708,GO:0098588,GO:0098609,GO:0098796,GO:0098797,GO:0098805,GO:0099503,GO:0101002,GO:0101003,GO:0140096,GO:1901214,GO:1901215,GO:1901564,GO:1902105,GO:1902107,GO:1902531,GO:1902533,GO:1902622,GO:1902624,GO:1903037,GO:1903038,GO:1903039,GO:1903317,GO:1903319,GO:1903506,GO:1903530,GO:1903532,GO:1903555,GO:1903557,GO:1903706,GO:1903708,GO:1904951,GO:2000026,GO:2000106,GO:2000108,GO:2000112,GO:2000145,GO:2000147,GO:2000307,GO:2000309,GO:2000389,GO:2000391,GO:2000398,GO:2000399,GO:2000401,GO:2000403,GO:2000404,GO:2000406,GO:2000410,GO:2000412,GO:2000413,GO:2000415,GO:2000416,GO:2000418,GO:2001141 - 0.0005064 52.0
HKD2_k127_5579436_2 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 440.0
HKD2_k127_5579436_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 438.0
HKD2_k127_5579436_4 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 420.0
HKD2_k127_5579436_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 404.0
HKD2_k127_5579436_6 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 346.0
HKD2_k127_5579436_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 347.0
HKD2_k127_5579436_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K13687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 346.0
HKD2_k127_5579436_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 324.0
HKD2_k127_5595463_0 COG1233 Phytoene dehydrogenase and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 619.0
HKD2_k127_5595463_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 480.0
HKD2_k127_5595463_10 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 291.0
HKD2_k127_5595463_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000048 287.0
HKD2_k127_5595463_12 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006731 303.0
HKD2_k127_5595463_13 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002813 271.0
HKD2_k127_5595463_14 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 259.0
HKD2_k127_5595463_15 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005334 245.0
HKD2_k127_5595463_16 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001072 246.0
HKD2_k127_5595463_17 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001212 254.0
HKD2_k127_5595463_18 L-lysine catabolic process to acetate - - - 0.000000000000000000000000000000000000000000000000000000000000000009803 235.0
HKD2_k127_5595463_19 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000002922 218.0
HKD2_k127_5595463_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 489.0
HKD2_k127_5595463_20 - - - - 0.00000000000000000000000000000000000000001758 166.0
HKD2_k127_5595463_21 mRNA catabolic process K06950 - - 0.000000000000000000000000000000000000002968 168.0
HKD2_k127_5595463_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000156 156.0
HKD2_k127_5595463_23 membrane - - - 0.000000000000000000000000000000000001535 146.0
HKD2_k127_5595463_24 Protein of unknown function (DUF2834) - - - 0.000000000000000000000000000000001382 151.0
HKD2_k127_5595463_25 COG2346, Truncated hemoglobins K03406,K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.00000000000000000000000000000004414 131.0
HKD2_k127_5595463_26 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000003564 127.0
HKD2_k127_5595463_27 O-Glycosyl hydrolase family 30 - - - 0.000000000000000000000000000009523 134.0
HKD2_k127_5595463_28 - - - - 0.00000000000000000000000000002302 127.0
HKD2_k127_5595463_29 DoxX-like family K15977 - - 0.0000000000000000000000000008598 120.0
HKD2_k127_5595463_3 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00055 - 1.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 394.0
HKD2_k127_5595463_30 Belongs to the universal stress protein A family - - - 0.0000000000000000000000001481 112.0
HKD2_k127_5595463_32 Putative DNA-binding domain - - - 0.000000000000000000000008531 116.0
HKD2_k127_5595463_33 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000636 117.0
HKD2_k127_5595463_34 denitrification pathway K02569 - - 0.0000000000000000004244 97.0
HKD2_k127_5595463_35 oxidoreductase K09471 - - 0.000000000000000004572 96.0
HKD2_k127_5595463_36 - - - - 0.00000000000000002901 93.0
HKD2_k127_5595463_37 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000003383 94.0
HKD2_k127_5595463_38 PFAM Glycosyl transferase, group 1 K19002 - 2.4.1.337 0.00000000000004552 86.0
HKD2_k127_5595463_39 - - - - 0.0000000000002265 78.0
HKD2_k127_5595463_4 diacylglycerol O-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 389.0
HKD2_k127_5595463_40 - - - - 0.0000000000002475 81.0
HKD2_k127_5595463_41 maltose O-acetyltransferase activity - - - 0.000000000001296 80.0
HKD2_k127_5595463_42 Adenylate cyclase - - - 0.000000000002686 81.0
HKD2_k127_5595463_44 - - - - 0.000000000005696 70.0
HKD2_k127_5595463_45 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.0000000001758 72.0
HKD2_k127_5595463_46 Peptidase family C25 - - - 0.0000000003223 73.0
HKD2_k127_5595463_47 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.000000003727 72.0
HKD2_k127_5595463_48 WD40-like Beta Propeller Repeat - - - 0.00000004415 68.0
HKD2_k127_5595463_49 Phosphopantetheine attachment site - - - 0.0002437 51.0
HKD2_k127_5595463_5 AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 379.0
HKD2_k127_5595463_50 - - - - 0.0006898 50.0
HKD2_k127_5595463_6 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 364.0
HKD2_k127_5595463_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 373.0
HKD2_k127_5595463_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 345.0
HKD2_k127_5595463_9 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 321.0
HKD2_k127_5599099_0 Heat shock 70 kDa protein K04043 - - 9.942e-269 842.0
HKD2_k127_5599099_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.073e-257 821.0
HKD2_k127_5599099_10 Alcohol dehydrogenase GroES-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 295.0
HKD2_k127_5599099_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001722 285.0
HKD2_k127_5599099_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005987 299.0
HKD2_k127_5599099_13 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000006302 276.0
HKD2_k127_5599099_14 COG2165 Type II secretory pathway, pseudopilin PulG K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000003624 163.0
HKD2_k127_5599099_15 Type IV pilus assembly protein PilM; K02461 - - 0.000000000000000000000000000000000000001551 170.0
HKD2_k127_5599099_16 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family K16048 - - 0.00000000000000000000000000000000000009367 150.0
HKD2_k127_5599099_17 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000001674 158.0
HKD2_k127_5599099_18 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000915 100.0
HKD2_k127_5599099_19 Hsp20/alpha crystallin family K13993 - - 0.000000000000000001104 91.0
HKD2_k127_5599099_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 602.0
HKD2_k127_5599099_20 Type II secretion system (T2SS), protein K - - - 0.00000000000000009673 95.0
HKD2_k127_5599099_21 PDZ DHR GLGF domain protein K02452 - - 0.000000007683 67.0
HKD2_k127_5599099_22 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00001774 47.0
HKD2_k127_5599099_23 TIGRFAM general secretion pathway protein H K08084 - - 0.0004408 52.0
HKD2_k127_5599099_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 469.0
HKD2_k127_5599099_4 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 437.0
HKD2_k127_5599099_5 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 422.0
HKD2_k127_5599099_6 Bacterial type II/III secretion system short domain K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 444.0
HKD2_k127_5599099_7 General secretion pathway protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 370.0
HKD2_k127_5599099_8 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 346.0
HKD2_k127_5599099_9 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 330.0
HKD2_k127_5609125_0 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 621.0
HKD2_k127_5609125_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 637.0
HKD2_k127_5609125_10 SnoaL-like domain - - - 0.000000000000000000000000000000000000006426 152.0
HKD2_k127_5609125_11 SnoaL-like polyketide cyclase - - - 0.0000000000000000000002446 110.0
HKD2_k127_5609125_12 - - - - 0.000000146 65.0
HKD2_k127_5609125_2 AMP-binding enzyme C-terminal domain K15868 - 6.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 567.0
HKD2_k127_5609125_3 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 403.0
HKD2_k127_5609125_4 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 400.0
HKD2_k127_5609125_5 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 385.0
HKD2_k127_5609125_6 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 362.0
HKD2_k127_5609125_7 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 306.0
HKD2_k127_5609125_8 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009704 282.0
HKD2_k127_5609125_9 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000000000000000000000001717 195.0
HKD2_k127_5626168_0 LeuA allosteric (dimerisation) domain K09011 - 2.3.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 507.0
HKD2_k127_5626168_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 473.0
HKD2_k127_5626168_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000001544 166.0
HKD2_k127_5626168_11 FAD linked oxidases, C-terminal domain K11472 - - 0.000000000000000000000000000000000000000258 173.0
HKD2_k127_5626168_12 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000009833 120.0
HKD2_k127_5626168_13 belongs to the wrba family K03809 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.2 0.0000000000000000000005088 102.0
HKD2_k127_5626168_14 heme oxygenase (decyclizing) activity - - - 0.00000000000000000004813 103.0
HKD2_k127_5626168_15 - - - - 0.0000000000000002824 88.0
HKD2_k127_5626168_2 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 395.0
HKD2_k127_5626168_3 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 353.0
HKD2_k127_5626168_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004539 267.0
HKD2_k127_5626168_5 PFAM glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006896 249.0
HKD2_k127_5626168_6 ThiJ PfpI - - - 0.000000000000000000000000000000000000000000000000000000000000000001558 243.0
HKD2_k127_5626168_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000002268 204.0
HKD2_k127_5626168_8 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000000009351 165.0
HKD2_k127_5626168_9 Sugar (and other) transporter K03446 - - 0.0000000000000000000000000000000000000001476 158.0
HKD2_k127_5629690_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.989e-228 717.0
HKD2_k127_5629690_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 534.0
HKD2_k127_5629690_10 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000004298 233.0
HKD2_k127_5629690_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000001736 173.0
HKD2_k127_5629690_12 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000003839 168.0
HKD2_k127_5629690_13 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000002454 178.0
HKD2_k127_5629690_14 Periplasmic binding protein K02016 - - 0.00000000000000000000000000001163 132.0
HKD2_k127_5629690_15 - - - - 0.0000000000000000000000000001262 129.0
HKD2_k127_5629690_16 Universal stress protein - - - 0.0000000000000000000000001487 116.0
HKD2_k127_5629690_17 - - - - 0.00000000000000000004083 102.0
HKD2_k127_5629690_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000002527 103.0
HKD2_k127_5629690_19 Psort location CytoplasmicMembrane, score K02237 - - 0.000000000000002943 80.0
HKD2_k127_5629690_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 454.0
HKD2_k127_5629690_20 - - - - 0.0000000133 66.0
HKD2_k127_5629690_21 Dihydrodipicolinate synthase N-acetylneuraminate lyase K01714 - 4.3.3.7 0.00000001429 66.0
HKD2_k127_5629690_22 Sigma-70, region 4 K03088 - - 0.000001358 56.0
HKD2_k127_5629690_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 420.0
HKD2_k127_5629690_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 388.0
HKD2_k127_5629690_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005735 347.0
HKD2_k127_5629690_6 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000004782 270.0
HKD2_k127_5629690_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000007503 240.0
HKD2_k127_5629690_8 Amidohydrolase family K01443,K16786,K16787 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000001084 231.0
HKD2_k127_5629690_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000002422 235.0
HKD2_k127_5696694_0 Cytochrome C and Quinol oxidase polypeptide I - - - 4.775e-258 818.0
HKD2_k127_5696694_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 607.0
HKD2_k127_5696694_10 Cytochrome c - - - 0.000000000000000000000000000000000000003602 156.0
HKD2_k127_5696694_11 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000144 167.0
HKD2_k127_5696694_12 SCO1/SenC K07152,K08976 - - 0.000000000000000000000000006225 118.0
HKD2_k127_5696694_13 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000434 126.0
HKD2_k127_5696694_14 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000002492 102.0
HKD2_k127_5696694_15 AsmA-like C-terminal region - - - 0.00000000000000004593 96.0
HKD2_k127_5696694_17 PFAM helix-turn-helix domain protein - - - 0.00000005846 67.0
HKD2_k127_5696694_2 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 542.0
HKD2_k127_5696694_3 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 330.0
HKD2_k127_5696694_4 Cytochrome C oxidase subunit II, periplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004703 262.0
HKD2_k127_5696694_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000007162 256.0
HKD2_k127_5696694_6 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007982 254.0
HKD2_k127_5696694_7 Cytochrome c oxidase subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000101 218.0
HKD2_k127_5696694_8 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000002376 183.0
HKD2_k127_5696694_9 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000003387 156.0
HKD2_k127_5711177_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1296.0
HKD2_k127_5711177_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 1.394e-316 984.0
HKD2_k127_5711177_10 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000002561 246.0
HKD2_k127_5711177_11 Methyltransferase small domain K00598 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0051704 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000003245 250.0
HKD2_k127_5711177_12 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000006819 170.0
HKD2_k127_5711177_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000006095 145.0
HKD2_k127_5711177_14 PQQ-like domain - - - 0.00000000000000000005739 106.0
HKD2_k127_5711177_15 CRS1_YhbY K07574 - - 0.00000000000000001264 88.0
HKD2_k127_5711177_16 - - - - 0.00000001863 59.0
HKD2_k127_5711177_17 ig-like, plexins, transcription factors - - - 0.00005331 57.0
HKD2_k127_5711177_18 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.0003084 50.0
HKD2_k127_5711177_2 Multicopper oxidase K08100 - 1.3.3.5 2.185e-266 836.0
HKD2_k127_5711177_3 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 484.0
HKD2_k127_5711177_4 biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 393.0
HKD2_k127_5711177_5 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 351.0
HKD2_k127_5711177_6 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 364.0
HKD2_k127_5711177_7 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 342.0
HKD2_k127_5711177_8 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 317.0
HKD2_k127_5711177_9 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06136,K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000972 282.0
HKD2_k127_5744721_0 DNA polymerase III subunits gamma and tau domain III K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 384.0
HKD2_k127_5744721_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
HKD2_k127_5744721_2 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000001229 202.0
HKD2_k127_5744721_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000005044 133.0
HKD2_k127_5744721_4 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000003269 88.0
HKD2_k127_5744721_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000004449 76.0
HKD2_k127_5744721_6 Short-chain dehydrogenase reductase sdr - - - 0.0000000000007908 74.0
HKD2_k127_5812047_0 Circularly permuted ATP-grasp type 2 - - - 5.451e-239 762.0
HKD2_k127_5812047_1 succinylglutamate desuccinylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 450.0
HKD2_k127_5812047_10 Cytochrome C' - - - 0.00000000000001697 81.0
HKD2_k127_5812047_2 pfam abc-1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 434.0
HKD2_k127_5812047_3 Desuccinylase aspartoacylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 340.0
HKD2_k127_5812047_4 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 314.0
HKD2_k127_5812047_5 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002169 267.0
HKD2_k127_5812047_6 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000003055 185.0
HKD2_k127_5812047_7 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000002319 182.0
HKD2_k127_5812047_8 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000001258 145.0
HKD2_k127_5812047_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000003969 98.0
HKD2_k127_5924945_0 Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 470.0
HKD2_k127_5924945_1 PFAM Type II IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 403.0
HKD2_k127_5924945_10 - - - - 0.00000000000000000000000000000000000001504 160.0
HKD2_k127_5924945_11 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000001434 123.0
HKD2_k127_5924945_12 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000004196 138.0
HKD2_k127_5924945_13 Zn-dependent protease - - - 0.00000005751 65.0
HKD2_k127_5924945_2 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 329.0
HKD2_k127_5924945_3 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 341.0
HKD2_k127_5924945_4 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 322.0
HKD2_k127_5924945_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001779 265.0
HKD2_k127_5924945_6 PFAM 2-nitropropane dioxygenase NPD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003728 271.0
HKD2_k127_5924945_7 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001945 246.0
HKD2_k127_5924945_8 Enoyl-CoA hydratase K01692,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000001525 243.0
HKD2_k127_5924945_9 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004101 244.0
HKD2_k127_5983098_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 436.0
HKD2_k127_5983098_1 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 346.0
HKD2_k127_5983098_10 Lipopolysaccharide biosynthesis protein - - - 0.00000000000000000000000000000002744 143.0
HKD2_k127_5983098_11 Domain of unknown function (DUF4215) - - - 0.0000000000000000000000000000002057 134.0
HKD2_k127_5983098_12 eight transmembrane protein EpsH - - - 0.0000000000000000000000000002407 130.0
HKD2_k127_5983098_13 ATPase MipZ - - - 0.00000000000000000000003328 110.0
HKD2_k127_5983098_14 Carbohydrate-binding protein of the ER - - - 0.00000000000000000003077 101.0
HKD2_k127_5983098_15 PFAM Polysaccharide export protein K01991 - - 0.00000000000000000006662 103.0
HKD2_k127_5983098_2 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 336.0
HKD2_k127_5983098_3 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000002583 230.0
HKD2_k127_5983098_4 PFAM DUF218 domain - - - 0.000000000000000000000000000000000000000000002048 173.0
HKD2_k127_5983098_5 Oligosaccharide biosynthesis protein alg14 like - - - 0.000000000000000000000000000000000000000004003 161.0
HKD2_k127_5983098_6 Phytanoyl-CoA dioxygenase PhyH family protein - - - 0.000000000000000000000000000000000000000009246 177.0
HKD2_k127_5983098_7 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000005015 155.0
HKD2_k127_5983098_8 Phytanoyl-CoA dioxygenase PhyH family protein - - - 0.0000000000000000000000000000000000587 154.0
HKD2_k127_5983098_9 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000001178 144.0
HKD2_k127_5985906_0 F5/8 type C domain - - - 1.611e-306 970.0
HKD2_k127_5985906_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 6.537e-303 956.0
HKD2_k127_5985906_10 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000001619 118.0
HKD2_k127_5985906_11 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000002327 108.0
HKD2_k127_5985906_12 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.00004127 47.0
HKD2_k127_5985906_2 pyruvate kinase activity K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 597.0
HKD2_k127_5985906_3 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 536.0
HKD2_k127_5985906_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
HKD2_k127_5985906_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 369.0
HKD2_k127_5985906_6 Possible lysine decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 335.0
HKD2_k127_5985906_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000006309 255.0
HKD2_k127_5985906_8 COG0317 Guanosine polyphosphate pyrophosphohydrolases synthetases K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000007947 167.0
HKD2_k127_5985906_9 cytochrome P450 - - - 0.00000000000000000000000000007639 136.0
HKD2_k127_6020161_0 Acyclic terpene utilisation family protein AtuA - - - 2.776e-286 889.0
HKD2_k127_6020161_1 carboxylase K01968 - 6.4.1.4 7.429e-279 884.0
HKD2_k127_6020161_10 Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 443.0
HKD2_k127_6020161_11 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 456.0
HKD2_k127_6020161_12 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 439.0
HKD2_k127_6020161_13 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 391.0
HKD2_k127_6020161_14 COG0534 Na -driven multidrug efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 381.0
HKD2_k127_6020161_15 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 384.0
HKD2_k127_6020161_16 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 364.0
HKD2_k127_6020161_17 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 336.0
HKD2_k127_6020161_18 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 356.0
HKD2_k127_6020161_19 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 311.0
HKD2_k127_6020161_2 Flavoprotein involved in K transport K03379 - 1.14.13.22 1.746e-270 844.0
HKD2_k127_6020161_20 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 307.0
HKD2_k127_6020161_21 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 296.0
HKD2_k127_6020161_23 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 293.0
HKD2_k127_6020161_24 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000013 293.0
HKD2_k127_6020161_25 IQR COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004042 276.0
HKD2_k127_6020161_26 methyltransferase activity K18827 - 2.1.1.294,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000002008 254.0
HKD2_k127_6020161_27 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000448 247.0
HKD2_k127_6020161_28 Putative zinc-binding metallo-peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008665 248.0
HKD2_k127_6020161_29 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000002283 243.0
HKD2_k127_6020161_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.797e-248 787.0
HKD2_k127_6020161_30 extracellular polysaccharide biosynthetic process K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000001601 260.0
HKD2_k127_6020161_31 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000001324 264.0
HKD2_k127_6020161_32 -O-antigen K18814 - - 0.0000000000000000000000000000000000000000000000000000000000000000003743 259.0
HKD2_k127_6020161_33 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003093 237.0
HKD2_k127_6020161_34 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000005212 245.0
HKD2_k127_6020161_35 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000009401 220.0
HKD2_k127_6020161_36 Short-chain dehydrogenase reductase Sdr - - - 0.0000000000000000000000000000000000000000000000000000000008877 221.0
HKD2_k127_6020161_37 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000000000000000000000000000000000000000003903 199.0
HKD2_k127_6020161_38 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000003003 217.0
HKD2_k127_6020161_39 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000004644 208.0
HKD2_k127_6020161_4 Protein of unknown function (DUF3604) - - - 1.222e-200 650.0
HKD2_k127_6020161_40 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000006985 194.0
HKD2_k127_6020161_41 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000004082 190.0
HKD2_k127_6020161_42 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000001741 197.0
HKD2_k127_6020161_43 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000001233 187.0
HKD2_k127_6020161_44 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000004313 181.0
HKD2_k127_6020161_45 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000001014 173.0
HKD2_k127_6020161_46 transcriptional regulator - - - 0.0000000000000000000000000000000000000000008161 180.0
HKD2_k127_6020161_47 COG3000 Sterol desaturase - - - 0.00000000000000000000000000000000000000004535 173.0
HKD2_k127_6020161_48 - - - - 0.00000000000000000000000000000000000000007175 160.0
HKD2_k127_6020161_49 Thioesterase superfamily - - - 0.000000000000000000000000000000000000004354 163.0
HKD2_k127_6020161_5 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.859e-199 647.0
HKD2_k127_6020161_50 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000002474 143.0
HKD2_k127_6020161_51 SnoaL-like domain - - - 0.0000000000000000000000000000000001747 153.0
HKD2_k127_6020161_52 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain - - - 0.000000000000000000000000000000000259 141.0
HKD2_k127_6020161_53 SnoaL-like domain - - - 0.000000000000000000000000000000003308 134.0
HKD2_k127_6020161_54 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000006376 130.0
HKD2_k127_6020161_55 PFAM Polysaccharide biosynthesis export protein K01991 - - 0.00000000000000000000000000000007213 134.0
HKD2_k127_6020161_56 Uncharacterised protein family (UPF0227) - - - 0.000000000000000000000000000505 123.0
HKD2_k127_6020161_57 Cadherin repeats. - - - 0.0000000000000000000000002926 124.0
HKD2_k127_6020161_58 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000000000004715 114.0
HKD2_k127_6020161_59 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.000000000000000000000705 104.0
HKD2_k127_6020161_6 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 600.0
HKD2_k127_6020161_60 - - - - 0.00000000000000000001882 102.0
HKD2_k127_6020161_61 lipolytic protein G-D-S-L family - - - 0.0000000000000000004203 99.0
HKD2_k127_6020161_62 Sh3 type 3 domain protein - - - 0.00000000000000003292 98.0
HKD2_k127_6020161_63 CopC domain - - - 0.00000000000000007537 94.0
HKD2_k127_6020161_64 Ion channel - - - 0.0000000000000004323 93.0
HKD2_k127_6020161_66 Antibiotic biosynthesis monooxygenase - - - 0.000000000000004951 89.0
HKD2_k127_6020161_67 lipolytic protein G-D-S-L family - - - 0.00000000000003326 85.0
HKD2_k127_6020161_69 Protein of unknown function (DUF3108) - - - 0.0000000000003697 84.0
HKD2_k127_6020161_7 COG1055 Na H antiporter NhaD and related arsenite - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 578.0
HKD2_k127_6020161_70 Sh3 type 3 domain protein - - - 0.0000000000008731 83.0
HKD2_k127_6020161_71 Evidence 5 No homology to any previously reported sequences - - - 0.000000000002469 80.0
HKD2_k127_6020161_72 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.000000000002882 77.0
HKD2_k127_6020161_74 Xylose isomerase-like TIM barrel - - - 0.00000000009145 74.0
HKD2_k127_6020161_75 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 0.000000001218 61.0
HKD2_k127_6020161_76 Belongs to the P(II) protein family K04752 - - 0.000005398 56.0
HKD2_k127_6020161_77 Protein of unknown function (DUF3187) - - - 0.00001024 58.0
HKD2_k127_6020161_78 Protein of unknown function (DUF2846) - - - 0.00001284 57.0
HKD2_k127_6020161_79 Cystathionine beta-synthase K01697 - 4.2.1.22 0.00002982 53.0
HKD2_k127_6020161_8 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 578.0
HKD2_k127_6020161_80 Lamin Tail Domain K07004 - - 0.0000517 55.0
HKD2_k127_6020161_81 PEP-CTERM motif - - - 0.0008446 50.0
HKD2_k127_6020161_9 COG3119 Arylsulfatase A and related enzymes K01137 - 3.1.6.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 539.0
HKD2_k127_6103376_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 597.0
HKD2_k127_6103376_1 Belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 623.0
HKD2_k127_6103376_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 495.0
HKD2_k127_6103376_3 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 427.0
HKD2_k127_6103376_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 385.0
HKD2_k127_6103376_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 329.0
HKD2_k127_6103376_6 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
HKD2_k127_6103376_7 transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007904 269.0
HKD2_k127_6103376_8 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000000000000000000000797 102.0
HKD2_k127_6103376_9 Major facilitator superfamily K05819 - - 0.00000000006232 74.0
HKD2_k127_6156025_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 6.964e-290 896.0
HKD2_k127_6156025_1 all-trans-retinol 13,14-reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 586.0
HKD2_k127_6156025_2 Transmembrane protein of unknown function (DUF3556) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 524.0
HKD2_k127_6156025_3 - - - - 0.0000000000000000000000000000000000000001954 157.0
HKD2_k127_6156025_4 Limonene-1,2-epoxide hydrolase - - - 0.00000000000000000000000000000009554 127.0
HKD2_k127_6156025_6 - - - - 0.0002878 52.0
HKD2_k127_6263777_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1052.0
HKD2_k127_6263777_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 604.0
HKD2_k127_6263777_10 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000008635 229.0
HKD2_k127_6263777_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000148 216.0
HKD2_k127_6263777_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000008682 192.0
HKD2_k127_6263777_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000007535 199.0
HKD2_k127_6263777_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000766 186.0
HKD2_k127_6263777_15 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000774 165.0
HKD2_k127_6263777_16 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001059 165.0
HKD2_k127_6263777_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000006421 154.0
HKD2_k127_6263777_18 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000002727 112.0
HKD2_k127_6263777_19 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000003441 111.0
HKD2_k127_6263777_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 491.0
HKD2_k127_6263777_20 Protein of unknown function (DUF2662) - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.0000000000004146 77.0
HKD2_k127_6263777_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 415.0
HKD2_k127_6263777_4 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 395.0
HKD2_k127_6263777_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 347.0
HKD2_k127_6263777_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 310.0
HKD2_k127_6263777_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000008779 286.0
HKD2_k127_6263777_8 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001955 282.0
HKD2_k127_6263777_9 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000003637 266.0
HKD2_k127_6335497_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.358e-221 703.0
HKD2_k127_6335497_1 glutamate--cysteine ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 503.0
HKD2_k127_6335497_10 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 366.0
HKD2_k127_6335497_11 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 359.0
HKD2_k127_6335497_12 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 364.0
HKD2_k127_6335497_13 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 366.0
HKD2_k127_6335497_14 Protein of unknown function (DUF2855) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 360.0
HKD2_k127_6335497_15 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003558 248.0
HKD2_k127_6335497_16 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000442 246.0
HKD2_k127_6335497_17 - - - - 0.000000000000000000000000000000000000000000000000000000008135 205.0
HKD2_k127_6335497_18 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000001087 205.0
HKD2_k127_6335497_19 glutathione transferase activity K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000005776 188.0
HKD2_k127_6335497_2 PFAM ABC transporter K02471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 493.0
HKD2_k127_6335497_20 Sensors of blue-light using FAD - - - 0.000000000000000000000000000000000000000001549 160.0
HKD2_k127_6335497_21 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000001792 130.0
HKD2_k127_6335497_22 - - - - 0.0000000000000000000000002749 115.0
HKD2_k127_6335497_23 IMP dehydrogenase activity - - - 0.000000000000000000000001513 111.0
HKD2_k127_6335497_24 Belongs to the P(II) protein family - - - 0.0000000000000000000003728 110.0
HKD2_k127_6335497_25 Domain of unknown function (DUF1330) - - - 0.000000000000000000006858 105.0
HKD2_k127_6335497_26 - - - - 0.00000000000000000008146 97.0
HKD2_k127_6335497_27 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000001174 95.0
HKD2_k127_6335497_28 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000001381 73.0
HKD2_k127_6335497_29 Integral membrane protein TerC family - - - 0.0000007732 52.0
HKD2_k127_6335497_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 491.0
HKD2_k127_6335497_30 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000002084 60.0
HKD2_k127_6335497_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 470.0
HKD2_k127_6335497_5 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 471.0
HKD2_k127_6335497_6 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 436.0
HKD2_k127_6335497_7 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 389.0
HKD2_k127_6335497_8 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 379.0
HKD2_k127_6335497_9 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 378.0
HKD2_k127_6339811_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 2.527e-225 726.0
HKD2_k127_6339811_1 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 548.0
HKD2_k127_6339811_2 lipid-transfer protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 501.0
HKD2_k127_6339811_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 448.0
HKD2_k127_6339811_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 369.0
HKD2_k127_6339811_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 333.0
HKD2_k127_6339811_6 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 325.0
HKD2_k127_6339811_7 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000002061 168.0
HKD2_k127_6339811_8 MaoC like domain - - - 0.0000000000000000000000000000000000000002247 168.0
HKD2_k127_6339811_9 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000005555 93.0
HKD2_k127_6409978_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 592.0
HKD2_k127_6409978_1 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 372.0
HKD2_k127_6409978_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000002288 243.0
HKD2_k127_6409978_3 EamA-like transporter family K05786 - - 0.0000000000000000000000000000000000000000000000000001773 192.0
HKD2_k127_6409978_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000007155 191.0
HKD2_k127_6409978_5 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000007136 170.0
HKD2_k127_6409978_6 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000002525 151.0
HKD2_k127_6409978_7 Responsible for synthesis of pseudouridine from uracil K06179,K06180 - 5.4.99.23,5.4.99.24 0.000000000000000000000000001336 130.0
HKD2_k127_6409978_8 Protein of unknown function (DUF1329) - - - 0.00000000000000000006421 103.0
HKD2_k127_6409978_9 PD-(D/E)XK nuclease superfamily - - - 0.0000000001915 75.0
HKD2_k127_649651_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 561.0
HKD2_k127_649651_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 479.0
HKD2_k127_649651_10 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000005384 179.0
HKD2_k127_649651_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000006237 172.0
HKD2_k127_649651_12 S1/P1 Nuclease - - - 0.000000000000000000000000000000000000000003137 166.0
HKD2_k127_649651_13 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000004476 125.0
HKD2_k127_649651_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000136 107.0
HKD2_k127_649651_15 phage shock protein E K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000000000000006532 94.0
HKD2_k127_649651_16 FecR protein - - - 0.000000001291 64.0
HKD2_k127_649651_17 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00001534 56.0
HKD2_k127_649651_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 380.0
HKD2_k127_649651_3 Sugar (and other) transporter K03446 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 365.0
HKD2_k127_649651_4 o-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004369 275.0
HKD2_k127_649651_5 Peptidase family S49 K04773,K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001767 287.0
HKD2_k127_649651_6 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000005342 235.0
HKD2_k127_649651_7 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000001592 230.0
HKD2_k127_649651_8 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000001984 220.0
HKD2_k127_649651_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000001778 209.0
HKD2_k127_6508142_0 tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 482.0
HKD2_k127_6508142_1 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 428.0
HKD2_k127_6508142_10 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000008263 154.0
HKD2_k127_6508142_11 methyltransferase activity - - - 0.00000000000000000000000000000000000007841 151.0
HKD2_k127_6508142_12 Domain of unknown function (DUF4184) - - - 0.0000000000000000000000000000000000004401 150.0
HKD2_k127_6508142_13 thiolester hydrolase activity - - - 0.000000000000000000000000000000005975 132.0
HKD2_k127_6508142_14 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000001284 135.0
HKD2_k127_6508142_15 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000005947 129.0
HKD2_k127_6508142_17 - - - - 0.0000000000000002606 86.0
HKD2_k127_6508142_18 - - - - 0.0000000000001063 83.0
HKD2_k127_6508142_19 amidinotransferase - GO:0003674,GO:0003824,GO:0016403,GO:0016787,GO:0016810,GO:0016813 - 0.0000000001371 74.0
HKD2_k127_6508142_2 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 388.0
HKD2_k127_6508142_20 Anti-sigma-K factor rskA - - - 0.0000006335 62.0
HKD2_k127_6508142_21 Tetratricopeptide repeat - - - 0.00002914 51.0
HKD2_k127_6508142_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K07250 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 332.0
HKD2_k127_6508142_4 alpha beta - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 317.0
HKD2_k127_6508142_5 Succinylglutamic semialdehyde dehydrogenase K06447 - 1.2.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 316.0
HKD2_k127_6508142_6 N-succinyltransferase beta subunit K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000000000000000009774 263.0
HKD2_k127_6508142_7 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000001457 179.0
HKD2_k127_6508142_8 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000005046 176.0
HKD2_k127_6508142_9 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000002587 156.0
HKD2_k127_6638344_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 4.572e-290 918.0
HKD2_k127_6638344_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 613.0
HKD2_k127_6638344_10 UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000001325 112.0
HKD2_k127_6638344_11 - - - - 0.000000000000000000006109 94.0
HKD2_k127_6638344_12 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000676 93.0
HKD2_k127_6638344_13 Belongs to the Nudix hydrolase family - - - 0.000000000001636 70.0
HKD2_k127_6638344_14 Alpha beta hydrolase - - - 0.00000000002605 74.0
HKD2_k127_6638344_2 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 424.0
HKD2_k127_6638344_3 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 364.0
HKD2_k127_6638344_4 cytochrome p450 K21033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 317.0
HKD2_k127_6638344_5 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000004657 235.0
HKD2_k127_6638344_6 Serine/Threonine protein kinases, catalytic domain K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000000000000007322 219.0
HKD2_k127_6638344_8 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000006206 130.0
HKD2_k127_6638344_9 - - - - 0.0000000000000000000000000001141 121.0
HKD2_k127_663864_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 359.0
HKD2_k127_663864_1 cytochrome p450 K16046 - 1.14.13.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 329.0
HKD2_k127_663864_2 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002443 280.0
HKD2_k127_663864_3 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001376 268.0
HKD2_k127_663864_4 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000004496 211.0
HKD2_k127_663864_5 CoA-transferase family III - - - 0.00000000000000000000000000000000001143 139.0
HKD2_k127_663864_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000005172 124.0
HKD2_k127_6646872_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.66e-228 714.0
HKD2_k127_6646872_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.542e-205 659.0
HKD2_k127_6646872_10 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000002849 93.0
HKD2_k127_6646872_2 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
HKD2_k127_6646872_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000002521 229.0
HKD2_k127_6646872_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000001164 178.0
HKD2_k127_6646872_5 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000007073 168.0
HKD2_k127_6646872_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000006598 179.0
HKD2_k127_6646872_7 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000001079 131.0
HKD2_k127_6646872_8 phospholipase Carboxylesterase K06999 - - 0.00000000000000000000000000004023 126.0
HKD2_k127_6646872_9 Late embryogenesis abundant protein - - - 0.0000000000000000004104 103.0
HKD2_k127_6647009_0 Fumarate reductase flavoprotein C-term - - - 2.966e-207 659.0
HKD2_k127_6647009_1 Leucyl-tRNA synthetase, Domain 2 K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 512.0
HKD2_k127_6647009_10 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 315.0
HKD2_k127_6647009_11 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 302.0
HKD2_k127_6647009_12 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003443 250.0
HKD2_k127_6647009_13 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000001311 244.0
HKD2_k127_6647009_14 Phosphoesterase DHHA1 - - - 0.000000000000000000000000000000000000000000006254 173.0
HKD2_k127_6647009_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000003453 114.0
HKD2_k127_6647009_16 Belongs to the BolA IbaG family K05527 - - 0.0000000000000006804 89.0
HKD2_k127_6647009_18 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 GO:0000104,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008177,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016627,GO:0016635,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803 - 0.0000001006 66.0
HKD2_k127_6647009_19 RNA-binding protein containing a PIN domain - - - 0.00005239 56.0
HKD2_k127_6647009_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 502.0
HKD2_k127_6647009_20 protein conserved in bacteria K01768 - 4.6.1.1 0.0009765 48.0
HKD2_k127_6647009_3 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 421.0
HKD2_k127_6647009_4 Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively K00032,K00090,K18916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008873,GO:0008875,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0019520,GO:0019522,GO:0019752,GO:0030267,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046181,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.215,1.1.1.43,1.1.1.79,1.1.1.81,1.20.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 407.0
HKD2_k127_6647009_5 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 398.0
HKD2_k127_6647009_6 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 392.0
HKD2_k127_6647009_7 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 385.0
HKD2_k127_6647009_8 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 346.0
HKD2_k127_6647009_9 Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 305.0
HKD2_k127_6704061_0 Protein of unknown function (DUF3604) - - - 2.788e-241 771.0
HKD2_k127_6704061_1 AMP-binding enzyme C-terminal domain K00666,K18688 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 611.0
HKD2_k127_6704061_10 LysM domain K16291 - - 0.0000000000000000000000000000000000000000000001028 188.0
HKD2_k127_6704061_11 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000004755 156.0
HKD2_k127_6704061_12 Lipoate-protein ligase - - - 0.0000000000000000000000000000000000000004171 160.0
HKD2_k127_6704061_13 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000006845 147.0
HKD2_k127_6704061_14 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000001372 111.0
HKD2_k127_6704061_15 PFAM thioesterase superfamily protein - - - 0.000000000000000007069 98.0
HKD2_k127_6704061_16 Hsp70 protein - - - 0.00001235 58.0
HKD2_k127_6704061_2 FAD dependent oxidoreductase K00244,K16051 - 1.3.5.4,1.3.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 436.0
HKD2_k127_6704061_3 Na melibiose symporter and related transporters K03292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 443.0
HKD2_k127_6704061_4 DbpA RNA binding domain K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 416.0
HKD2_k127_6704061_5 cytochrome P-450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 338.0
HKD2_k127_6704061_6 PFAM fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 300.0
HKD2_k127_6704061_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001044 248.0
HKD2_k127_6704061_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
HKD2_k127_6704061_9 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000002735 228.0
HKD2_k127_6742394_0 General secretory system II, protein E domain protein K02652 - - 5.635e-251 809.0
HKD2_k127_6742394_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 597.0
HKD2_k127_6742394_10 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 317.0
HKD2_k127_6742394_11 Neisseria PilC beta-propeller domain K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 325.0
HKD2_k127_6742394_12 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000192 311.0
HKD2_k127_6742394_13 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000681 306.0
HKD2_k127_6742394_14 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000003053 267.0
HKD2_k127_6742394_15 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000009236 268.0
HKD2_k127_6742394_16 HflC and HflK could encode or regulate a protease K04088 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000001115 246.0
HKD2_k127_6742394_17 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000001253 236.0
HKD2_k127_6742394_18 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000001289 225.0
HKD2_k127_6742394_19 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000001518 191.0
HKD2_k127_6742394_2 response regulator K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 499.0
HKD2_k127_6742394_20 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000006326 188.0
HKD2_k127_6742394_21 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000002532 188.0
HKD2_k127_6742394_22 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000002275 180.0
HKD2_k127_6742394_23 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000683 156.0
HKD2_k127_6742394_24 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000004934 142.0
HKD2_k127_6742394_25 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000006423 139.0
HKD2_k127_6742394_26 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.000000000000000000000000000003842 141.0
HKD2_k127_6742394_27 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000003135 127.0
HKD2_k127_6742394_28 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000015 123.0
HKD2_k127_6742394_29 Fimbrial assembly protein (PilN) K02663 - - 0.000000000000000001501 100.0
HKD2_k127_6742394_3 response regulator K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 464.0
HKD2_k127_6742394_30 Roadblock/LC7 domain - - - 0.000000000000005108 79.0
HKD2_k127_6742394_31 sequence-specific DNA binding - - - 0.00000000000000811 79.0
HKD2_k127_6742394_32 Pilus assembly protein, PilP K02665 - - 0.000000000001636 79.0
HKD2_k127_6742394_33 RHS Repeat - - - 0.0000000000225 79.0
HKD2_k127_6742394_34 PFAM permease YjgP YjgQ family protein K11720 - - 0.000000005684 68.0
HKD2_k127_6742394_35 pilus assembly protein PilW - - - 0.00000001497 66.0
HKD2_k127_6742394_36 Homologues of snake disintegrins - - - 0.000001912 61.0
HKD2_k127_6742394_37 - - - - 0.00001035 48.0
HKD2_k127_6742394_38 Type II transport protein GspH K08084 - - 0.00001291 57.0
HKD2_k127_6742394_39 amine dehydrogenase activity - - - 0.00002091 59.0
HKD2_k127_6742394_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 401.0
HKD2_k127_6742394_40 Helix-turn-helix - - - 0.0005415 48.0
HKD2_k127_6742394_41 Prokaryotic N-terminal methylation motif K02458,K02671 - - 0.0006617 51.0
HKD2_k127_6742394_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 380.0
HKD2_k127_6742394_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 378.0
HKD2_k127_6742394_7 Nucleoside recognition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 370.0
HKD2_k127_6742394_8 pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 338.0
HKD2_k127_6742394_9 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 351.0
HKD2_k127_6750054_0 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 432.0
HKD2_k127_6750054_1 phospholipase C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005871 287.0
HKD2_k127_6750054_2 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000003276 276.0
HKD2_k127_6750054_3 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000007658 259.0
HKD2_k127_6750054_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005101 252.0
HKD2_k127_6750054_5 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000008787 212.0
HKD2_k127_6750054_6 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000008123 165.0
HKD2_k127_6750054_7 SnoaL-like domain - - - 0.000000000000000000009533 106.0
HKD2_k127_6785431_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1330.0
HKD2_k127_6785431_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 411.0
HKD2_k127_6785431_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 299.0
HKD2_k127_6785431_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 262.0
HKD2_k127_6785431_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000002238 183.0
HKD2_k127_6785431_5 PFAM Sulfate transporter family K03321 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015106,GO:0015318,GO:0015701,GO:0015711,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656 - 0.00000000000000000000004537 104.0
HKD2_k127_6785431_6 PFAM nucleoside H symporter K05820 - - 0.000000000000000000002345 110.0
HKD2_k127_6891650_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 520.0
HKD2_k127_6891650_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 473.0
HKD2_k127_6891650_10 COG0489 ATPases involved in chromosome partitioning K00903 - 2.7.10.2 0.00000000000000000000000000000000000000007351 162.0
HKD2_k127_6891650_11 Lysin motif - - - 0.000000000000000000000000000000000004555 156.0
HKD2_k127_6891650_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 461.0
HKD2_k127_6891650_3 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 376.0
HKD2_k127_6891650_4 NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009138 301.0
HKD2_k127_6891650_5 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000509 270.0
HKD2_k127_6891650_6 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000006735 232.0
HKD2_k127_6891650_7 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000004866 219.0
HKD2_k127_6891650_8 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000007183 186.0
HKD2_k127_6891650_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000007628 187.0
HKD2_k127_7034821_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 9.252e-254 812.0
HKD2_k127_7034821_1 PFAM UBA THIF-type NAD FAD binding K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007644 482.0
HKD2_k127_7034821_2 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 396.0
HKD2_k127_7034821_3 SCP-2 sterol transfer family - - - 0.00002854 58.0
HKD2_k127_7034821_4 - - - - 0.0001078 46.0
HKD2_k127_7180968_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 593.0
HKD2_k127_7180968_1 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 599.0
HKD2_k127_7180968_10 - - - - 0.000000000000000000000000000000000004033 158.0
HKD2_k127_7180968_11 UPF0060 membrane protein K09771 - - 0.000000000000000000000000000000007517 142.0
HKD2_k127_7180968_12 Lipocalin-like domain K03098 - - 0.0000000000000000000000000002713 117.0
HKD2_k127_7180968_13 protein conserved in bacteria - - - 0.00000000000000000002747 100.0
HKD2_k127_7180968_14 TonB C terminal K03832 - - 0.000346 54.0
HKD2_k127_7180968_2 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 523.0
HKD2_k127_7180968_3 dioxygenase K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 466.0
HKD2_k127_7180968_4 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 399.0
HKD2_k127_7180968_5 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 321.0
HKD2_k127_7180968_6 Enoyl-(Acyl carrier protein) reductase K18009 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000003589 276.0
HKD2_k127_7180968_7 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000001403 213.0
HKD2_k127_7180968_8 Bacterial periplasmic substrate-binding proteins K01713 - 4.2.1.51,4.2.1.91 0.00000000000000000000000000000000000000000000000653 196.0
HKD2_k127_7180968_9 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000001402 166.0
HKD2_k127_73625_0 Flavin-binding monooxygenase-like K03379,K18091 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576 1.14.13.170,1.14.13.171,1.14.13.22 6.903e-264 836.0
HKD2_k127_73625_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 539.0
HKD2_k127_73625_2 Acyl-CoA dehydrogenase, middle domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 456.0
HKD2_k127_73625_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 332.0
HKD2_k127_73625_4 COG0183 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 344.0
HKD2_k127_73625_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000393 204.0
HKD2_k127_73625_6 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000005627 199.0
HKD2_k127_73625_7 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000002413 109.0
HKD2_k127_7586770_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 513.0
HKD2_k127_7586770_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 359.0
HKD2_k127_7586770_2 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
HKD2_k127_7586770_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001052 269.0
HKD2_k127_7586770_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000002926 151.0
HKD2_k127_7586770_6 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000007362 87.0
HKD2_k127_7586770_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000001278 72.0
HKD2_k127_7655520_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 2.381e-242 758.0
HKD2_k127_7655520_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 6.919e-194 622.0
HKD2_k127_7655520_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 593.0
HKD2_k127_7655520_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 351.0
HKD2_k127_7655520_4 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000000000000000000000000001478 224.0
HKD2_k127_7655520_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000001824 186.0
HKD2_k127_7655520_6 acyl-CoA dehydrogenase - - - 0.00000000000004815 72.0
HKD2_k127_7655520_7 Peptidase family C25 - - - 0.000004795 60.0
HKD2_k127_7682675_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.726e-262 830.0
HKD2_k127_7682675_1 Protein of unknown function (DUF1254) - - - 7.96e-239 746.0
HKD2_k127_7682675_10 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000003744 223.0
HKD2_k127_7682675_11 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000003932 216.0
HKD2_k127_7682675_12 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000006053 199.0
HKD2_k127_7682675_13 nucleic-acid-binding protein containing a zn-ribbon K07068 - - 0.00000000000000000000000000000000000000000000001759 179.0
HKD2_k127_7682675_14 COG2977 Phosphopantetheinyl transferase component of siderophore synthetase - - - 0.00000000000000000000000000344 130.0
HKD2_k127_7682675_15 - - - - 0.00000000000000000000004764 115.0
HKD2_k127_7682675_16 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000004052 69.0
HKD2_k127_7682675_2 acyl-CoA dehydrogenase K00257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 563.0
HKD2_k127_7682675_3 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 546.0
HKD2_k127_7682675_4 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 383.0
HKD2_k127_7682675_5 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 356.0
HKD2_k127_7682675_7 PFAM Alpha beta hydrolase fold-3 domain protein K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 340.0
HKD2_k127_7682675_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002246 271.0
HKD2_k127_7682675_9 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003069 274.0
HKD2_k127_7699187_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.879e-238 752.0
HKD2_k127_7699187_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 4.787e-220 710.0
HKD2_k127_7699187_10 Sulfate ABC transporter, permease K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 385.0
HKD2_k127_7699187_11 Binding-protein-dependent transport system inner membrane component K02046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 362.0
HKD2_k127_7699187_12 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 363.0
HKD2_k127_7699187_13 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 336.0
HKD2_k127_7699187_14 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007705 277.0
HKD2_k127_7699187_15 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001144 271.0
HKD2_k127_7699187_16 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001847 255.0
HKD2_k127_7699187_17 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003864 263.0
HKD2_k127_7699187_18 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002573 232.0
HKD2_k127_7699187_19 Sensor histidine kinase, Cache_1, HAMP and PAS domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000006539 232.0
HKD2_k127_7699187_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 590.0
HKD2_k127_7699187_20 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000003443 239.0
HKD2_k127_7699187_21 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000006003 215.0
HKD2_k127_7699187_22 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000002715 228.0
HKD2_k127_7699187_23 Peroxiredoxin 2 K03386,K13279 GO:0000122,GO:0000187,GO:0000302,GO:0000303,GO:0000305,GO:0001775,GO:0001932,GO:0001934,GO:0002237,GO:0002252,GO:0002376,GO:0002520,GO:0002532,GO:0002536,GO:0002679,GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0002831,GO:0002832,GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006357,GO:0006801,GO:0006950,GO:0006952,GO:0006954,GO:0006979,GO:0007162,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008283,GO:0008340,GO:0008379,GO:0008430,GO:0009056,GO:0009266,GO:0009408,GO:0009605,GO:0009607,GO:0009617,GO:0009628,GO:0009636,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010259,GO:0010286,GO:0010310,GO:0010468,GO:0010556,GO:0010558,GO:0010562,GO:0010604,GO:0010605,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010941,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0019219,GO:0019220,GO:0019222,GO:0019430,GO:0022407,GO:0022408,GO:0023051,GO:0023056,GO:0023057,GO:0030155,GO:0030193,GO:0030194,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031399,GO:0031401,GO:0031664,GO:0031665,GO:0032088,GO:0032101,GO:0032102,GO:0032147,GO:0032268,GO:0032270,GO:0032496,GO:0032501,GO:0032502,GO:0032943,GO:0033554,GO:0033674,GO:0033993,GO:0034599,GO:0034614,GO:0042098,GO:0042110,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042542,GO:0042592,GO:0042737,GO:0042743,GO:0042744,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043085,GO:0043207,GO:0043209,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043433,GO:0043523,GO:0043524,GO:0043549,GO:0043900,GO:0043901,GO:0044092,GO:0044093,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0045580,GO:0045581,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0045730,GO:0045859,GO:0045860,GO:0045892,GO:0045934,GO:0045937,GO:0046649,GO:0046651,GO:0046677,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048534,GO:0048538,GO:0048583,GO:0048584,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0048872,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050863,GO:0050865,GO:0050866,GO:0050868,GO:0050878,GO:0050896,GO:0051090,GO:0051093,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051186,GO:0051187,GO:0051193,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051249,GO:0051250,GO:0051252,GO:0051253,GO:0051338,GO:0051347,GO:0051704,GO:0051707,GO:0051716,GO:0051920,GO:0055114,GO:0060255,GO:0060548,GO:0061041,GO:0065007,GO:0065008,GO:0065009,GO:0070661,GO:0070887,GO:0071450,GO:0071451,GO:0071900,GO:0071902,GO:0072593,GO:0080090,GO:0080134,GO:0090303,GO:0097237,GO:0098754,GO:0098869,GO:1900046,GO:1900048,GO:1901099,GO:1901214,GO:1901215,GO:1901700,GO:1901701,GO:1902105,GO:1902106,GO:1902531,GO:1902533,GO:1902679,GO:1903034,GO:1903036,GO:1903037,GO:1903038,GO:1903506,GO:1903507,GO:1903706,GO:1903707,GO:1990748,GO:2000026,GO:2000112,GO:2000113,GO:2000377,GO:2000378,GO:2001141,GO:2001233,GO:2001234,GO:2001236,GO:2001237,GO:2001239,GO:2001240 1.11.1.15 0.0000000000000000000000000000000000000000000001701 178.0
HKD2_k127_7699187_24 ubiquinone biosynthetic process - - - 0.000000000000000000000000000000000000000634 163.0
HKD2_k127_7699187_25 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000004675 125.0
HKD2_k127_7699187_26 Response regulator, receiver - - - 0.000000000000000000000001223 112.0
HKD2_k127_7699187_27 transcriptional regulator K22107 - - 0.00000000000000000000003179 109.0
HKD2_k127_7699187_28 - - - - 0.0000000000000000001809 105.0
HKD2_k127_7699187_29 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000003966 92.0
HKD2_k127_7699187_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 568.0
HKD2_k127_7699187_30 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.000000000003264 72.0
HKD2_k127_7699187_31 protein conserved in bacteria K09908 - - 0.00000000003566 72.0
HKD2_k127_7699187_32 YceI-like domain - - - 0.0000000001452 69.0
HKD2_k127_7699187_4 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 570.0
HKD2_k127_7699187_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 485.0
HKD2_k127_7699187_6 PFAM acyl-CoA dehydrogenase domain protein K00249,K11731 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 462.0
HKD2_k127_7699187_7 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 442.0
HKD2_k127_7699187_8 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 430.0
HKD2_k127_7699187_9 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 402.0
HKD2_k127_7736150_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 554.0
HKD2_k127_7736150_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 473.0
HKD2_k127_7736150_10 Transcriptional Regulator, AraC family - - - 0.0000000000000000000000000000000001404 150.0
HKD2_k127_7736150_11 - - - - 0.00000000000000000000000000000007046 145.0
HKD2_k127_7736150_12 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000006064 119.0
HKD2_k127_7736150_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000547 81.0
HKD2_k127_7736150_14 TRAP transporter solute receptor TAXI family K07080 - - 0.0000000001243 74.0
HKD2_k127_7736150_2 PFAM Mammalian cell entry related domain protein K06192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 478.0
HKD2_k127_7736150_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 391.0
HKD2_k127_7736150_4 NAD dependent epimerase dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 346.0
HKD2_k127_7736150_5 Paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001474 262.0
HKD2_k127_7736150_6 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003829 243.0
HKD2_k127_7736150_7 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000007525 230.0
HKD2_k127_7736150_8 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000142 222.0
HKD2_k127_7736150_9 PFAM Paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000000000000000000000000000002238 201.0
HKD2_k127_774706_0 PFAM Glycosyl transferase family 2 K03669 - - 2.135e-232 772.0
HKD2_k127_774706_1 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 589.0
HKD2_k127_774706_10 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 312.0
HKD2_k127_774706_11 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 307.0
HKD2_k127_774706_12 transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002627 286.0
HKD2_k127_774706_13 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001937 256.0
HKD2_k127_774706_14 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000001875 240.0
HKD2_k127_774706_15 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.00000000000000000000000000000000000000000000000000000000000001987 239.0
HKD2_k127_774706_16 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000002388 203.0
HKD2_k127_774706_17 - - - - 0.0000000000000000000000000000000000000000000000009403 198.0
HKD2_k127_774706_18 - - - - 0.0000000000000000000000000000000000000003549 170.0
HKD2_k127_774706_19 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000006125 172.0
HKD2_k127_774706_2 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 563.0
HKD2_k127_774706_20 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000005001 153.0
HKD2_k127_774706_21 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000007122 167.0
HKD2_k127_774706_22 integral membrane protein - - - 0.00000000000000000000000005617 120.0
HKD2_k127_774706_23 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000001163 118.0
HKD2_k127_774706_24 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005576,GO:0005623,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0010646,GO:0010647,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0065007,GO:0065010,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:2000535 - 0.00000003474 55.0
HKD2_k127_774706_25 Domain of unknown function (DUF4874) - - - 0.0000003149 64.0
HKD2_k127_774706_26 GDSL-like protein K05970 - 3.1.1.53 0.00001802 56.0
HKD2_k127_774706_28 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0001787 53.0
HKD2_k127_774706_3 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 501.0
HKD2_k127_774706_4 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01634 - 4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 495.0
HKD2_k127_774706_5 ABC transporter substrate-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 420.0
HKD2_k127_774706_6 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 385.0
HKD2_k127_774706_7 Belongs to the ABC transporter superfamily K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 381.0
HKD2_k127_774706_8 carbohydrate binding K00702 - 2.4.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 330.0
HKD2_k127_774706_9 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 332.0
HKD2_k127_7794676_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 549.0
HKD2_k127_7794676_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007577 279.0
HKD2_k127_7794676_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007043 247.0
HKD2_k127_7794676_3 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000004467 217.0
HKD2_k127_7794676_4 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000003919 214.0
HKD2_k127_7794676_6 Limonene-12-epoxide hydrolase - - - 0.0000000000000000000000000000000000001062 158.0
HKD2_k127_7794676_7 Phytanoyl-CoA dioxygenase - - - 0.0000000000000000000000000000001057 137.0
HKD2_k127_7794676_8 - - - - 0.0000000000000000000000000006986 124.0
HKD2_k127_7825729_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 574.0
HKD2_k127_7825729_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 544.0
HKD2_k127_7825729_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 386.0
HKD2_k127_7825729_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 351.0
HKD2_k127_7825729_4 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 316.0
HKD2_k127_7825729_5 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000001537 237.0
HKD2_k127_7825729_6 - - - - 0.000000000000000000000000000000000000009122 158.0
HKD2_k127_7825729_7 - - - - 0.0000000000000000000000000000001232 128.0
HKD2_k127_7892158_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 614.0
HKD2_k127_7892158_1 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 546.0
HKD2_k127_7892158_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 391.0
HKD2_k127_7892158_11 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 355.0
HKD2_k127_7892158_12 Alkyl sulfatase dimerisation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 365.0
HKD2_k127_7892158_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 339.0
HKD2_k127_7892158_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 325.0
HKD2_k127_7892158_15 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 300.0
HKD2_k127_7892158_16 involved in sulfation activity towards typical ceramide glycolipids and trehalose glycolipids K01014 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006790,GO:0008146,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016782,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044272,GO:0044281,GO:0046505,GO:0046506,GO:0071704,GO:1901576 2.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 296.0
HKD2_k127_7892158_17 Copper resistance protein D K07245 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 303.0
HKD2_k127_7892158_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000102 266.0
HKD2_k127_7892158_19 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003554 253.0
HKD2_k127_7892158_2 cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 529.0
HKD2_k127_7892158_20 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases large terminal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000004468 237.0
HKD2_k127_7892158_21 HupE / UreJ protein K03192 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000002745 226.0
HKD2_k127_7892158_22 PFAM amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000003065 235.0
HKD2_k127_7892158_23 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000001199 181.0
HKD2_k127_7892158_24 response to heat K03668,K09914 - - 0.000000000000000000000000000000000002188 152.0
HKD2_k127_7892158_25 Cupin domain - - - 0.000000000000000000000000000001257 130.0
HKD2_k127_7892158_26 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000026 133.0
HKD2_k127_7892158_27 HupE / UreJ protein - - - 0.00000000000000000000000006731 122.0
HKD2_k127_7892158_28 - - - - 0.0000000000000000000001271 115.0
HKD2_k127_7892158_29 PPIC-type PPIASE domain - - - 0.000000000000000001844 87.0
HKD2_k127_7892158_3 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 515.0
HKD2_k127_7892158_30 Bacterial regulatory proteins, tetR family - - - 0.00000000000000002076 91.0
HKD2_k127_7892158_31 Sel1-like repeats. K07126 - - 0.00000000011 75.0
HKD2_k127_7892158_32 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000007991 58.0
HKD2_k127_7892158_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 481.0
HKD2_k127_7892158_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 481.0
HKD2_k127_7892158_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 490.0
HKD2_k127_7892158_7 cytochrome p450 K16046 - 1.14.13.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 451.0
HKD2_k127_7892158_8 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 406.0
HKD2_k127_7892158_9 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 409.0
HKD2_k127_7999950_0 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 537.0
HKD2_k127_7999950_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 423.0
HKD2_k127_7999950_10 helix_turn_helix, mercury resistance K22491 - - 0.00000000000000000000000000000000000000001721 165.0
HKD2_k127_7999950_11 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000001741 170.0
HKD2_k127_7999950_12 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000009132 149.0
HKD2_k127_7999950_13 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000003314 126.0
HKD2_k127_7999950_2 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 381.0
HKD2_k127_7999950_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 304.0
HKD2_k127_7999950_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002802 261.0
HKD2_k127_7999950_5 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003038 264.0
HKD2_k127_7999950_6 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005577 267.0
HKD2_k127_7999950_7 Nucleoside triphosphate K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000437 215.0
HKD2_k127_7999950_8 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000001187 189.0
HKD2_k127_7999950_9 YhhN family - - - 0.000000000000000000000000000000000000000000002689 175.0
HKD2_k127_8132215_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.415e-204 667.0
HKD2_k127_8132215_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 599.0
HKD2_k127_8132215_2 Trehalose utilisation K09992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 306.0
HKD2_k127_8132215_3 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 312.0
HKD2_k127_8132215_4 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005728 235.0
HKD2_k127_8132215_5 Cytidylate kinase-like family - - - 0.0000000000000000000000000245 118.0
HKD2_k127_8132215_6 AMP binding - - - 0.000000000000003387 86.0
HKD2_k127_8132215_7 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000003752 89.0
HKD2_k127_8132215_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000001271 83.0
HKD2_k127_8138777_0 PQQ-like domain K00117 - 1.1.5.2 2.535e-200 655.0
HKD2_k127_8138777_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 335.0
HKD2_k127_8138777_2 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000000000000000000000004231 186.0
HKD2_k127_8138777_3 Two component transcriptional regulator, winged helix family K07657 - - 0.00000000000000000000000000000000000001958 161.0
HKD2_k127_8138777_4 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000002056 122.0
HKD2_k127_8138777_5 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000000000126 105.0
HKD2_k127_81533_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1093.0
HKD2_k127_81533_1 TIGRFAM methylmalonyl-CoA mutase N-terminal domain K01847,K01848 - 5.4.99.2 1e-323 1037.0
HKD2_k127_81533_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001536 285.0
HKD2_k127_81533_11 Small GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000005681 228.0
HKD2_k127_81533_12 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000004239 179.0
HKD2_k127_81533_13 dioxygenase activity - - - 0.00000000000000000000000001298 120.0
HKD2_k127_81533_14 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000044 55.0
HKD2_k127_81533_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 2.037e-269 843.0
HKD2_k127_81533_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.657e-208 691.0
HKD2_k127_81533_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.251e-198 632.0
HKD2_k127_81533_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 575.0
HKD2_k127_81533_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 386.0
HKD2_k127_81533_7 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 375.0
HKD2_k127_81533_8 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 394.0
HKD2_k127_81533_9 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 306.0
HKD2_k127_8172112_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 619.0
HKD2_k127_8172112_1 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 575.0
HKD2_k127_8172112_2 short-chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
HKD2_k127_8172112_3 Acyl dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000003802 239.0
HKD2_k127_8172112_4 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000003813 186.0
HKD2_k127_8426034_0 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 455.0
HKD2_k127_8426034_1 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K20997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 428.0
HKD2_k127_8426034_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 321.0
HKD2_k127_8426034_3 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000002364 240.0
HKD2_k127_8426034_4 ABC-2 type transporter K09688,K09690,K09692 - - 0.00000000000000000000000000000000000000000000000000000000000002728 241.0
HKD2_k127_8426034_5 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000006161 199.0
HKD2_k127_8426034_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000008616 117.0
HKD2_k127_8426034_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000008792 79.0
HKD2_k127_8426034_8 eight transmembrane protein EpsH - - - 0.0005986 52.0
HKD2_k127_8465243_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.143e-270 859.0
HKD2_k127_8465243_1 Heat shock 70 kDa protein K04043 - - 4.459e-256 803.0
HKD2_k127_8465243_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004679 261.0
HKD2_k127_8465243_11 glutathione transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002804 243.0
HKD2_k127_8465243_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000003329 232.0
HKD2_k127_8465243_13 transmembrane signaling receptor activity K03406 - - 0.00000000000000000000000000000000000000000000000000000000000004188 235.0
HKD2_k127_8465243_14 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000004883 209.0
HKD2_k127_8465243_15 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000002896 231.0
HKD2_k127_8465243_16 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000009327 215.0
HKD2_k127_8465243_17 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000003139 199.0
HKD2_k127_8465243_18 response regulator K03413 - - 0.00000000000000000000000000000000001071 147.0
HKD2_k127_8465243_19 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000009172 137.0
HKD2_k127_8465243_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 595.0
HKD2_k127_8465243_20 chemotaxis protein K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.00000000000001745 81.0
HKD2_k127_8465243_21 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.000000000000388 79.0
HKD2_k127_8465243_22 Histidine Phosphotransfer domain - - - 0.00001251 58.0
HKD2_k127_8465243_23 Chemotaxis protein cheW K03408 - - 0.0002722 51.0
HKD2_k127_8465243_24 transcription factor (CBF NF-Y) - - - 0.000611 46.0
HKD2_k127_8465243_3 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 597.0
HKD2_k127_8465243_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 432.0
HKD2_k127_8465243_5 N-Acetylmuramoyl-L-alanine amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 358.0
HKD2_k127_8465243_6 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 306.0
HKD2_k127_8465243_7 Thioesterase-like superfamily K10805 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 304.0
HKD2_k127_8465243_8 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 289.0
HKD2_k127_8465243_9 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000194 267.0
HKD2_k127_8478934_0 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 4.737e-242 766.0
HKD2_k127_8478934_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 464.0
HKD2_k127_8478934_2 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 310.0
HKD2_k127_8478934_3 PFAM Enoyl-CoA hydratase isomerase K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 293.0
HKD2_k127_8478934_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003742 296.0
HKD2_k127_8478934_5 alpha-ribazole phosphatase activity K01834,K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.11,5.4.2.12 0.00000000000000000000000000000000000000000001114 173.0
HKD2_k127_8478934_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000001155 178.0
HKD2_k127_8478934_7 ergothioneine biosynthetic process K01919,K06048 - 6.3.2.2 0.0000000000000000000000000000000000000000314 166.0
HKD2_k127_8478934_8 DnaK suppressor protein - - - 0.000000000000000000001235 99.0
HKD2_k127_8489246_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 1.657e-289 916.0
HKD2_k127_8489246_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 2.069e-261 819.0
HKD2_k127_8489246_10 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000004562 238.0
HKD2_k127_8489246_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000001462 117.0
HKD2_k127_8489246_12 e3 binding domain - - - 0.000000000000000000000006721 105.0
HKD2_k127_8489246_13 Belongs to the CDS family K00981,K19664 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 0.000000000000006056 91.0
HKD2_k127_8489246_14 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000004295 70.0
HKD2_k127_8489246_15 hydrogen uptake protein K03605 - - 0.0001783 54.0
HKD2_k127_8489246_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 8.642e-224 721.0
HKD2_k127_8489246_3 Transketolase, C-terminal domain K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 507.0
HKD2_k127_8489246_4 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 456.0
HKD2_k127_8489246_5 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009033 437.0
HKD2_k127_8489246_6 Erythromycin esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 428.0
HKD2_k127_8489246_7 4Fe-4S dicluster domain K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 362.0
HKD2_k127_8489246_8 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 323.0
HKD2_k127_8489246_9 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001882 306.0
HKD2_k127_8581966_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 598.0
HKD2_k127_8581966_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 549.0
HKD2_k127_8581966_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000001134 184.0
HKD2_k127_8581966_11 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000001197 120.0
HKD2_k127_8581966_12 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000009162 115.0
HKD2_k127_8581966_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000003499 116.0
HKD2_k127_8581966_14 competence protein - - - 0.00000000000000000000000004264 126.0
HKD2_k127_8581966_15 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000008988 118.0
HKD2_k127_8581966_16 Helix-turn-helix domain - - - 0.0000000000000000000001626 113.0
HKD2_k127_8581966_17 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.00000000000000003463 89.0
HKD2_k127_8581966_2 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 532.0
HKD2_k127_8581966_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 455.0
HKD2_k127_8581966_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 362.0
HKD2_k127_8581966_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042,K17468 - 2.9.1.1,4.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 344.0
HKD2_k127_8581966_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 333.0
HKD2_k127_8581966_7 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 298.0
HKD2_k127_8581966_8 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003632 270.0
HKD2_k127_8581966_9 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000007038 228.0
HKD2_k127_8612241_0 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 363.0
HKD2_k127_8612241_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000122 249.0
HKD2_k127_8612241_10 - - - - 0.00000000000000000000003341 115.0
HKD2_k127_8612241_11 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000001484 93.0
HKD2_k127_8612241_12 Arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.0000002181 55.0
HKD2_k127_8612241_2 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001711 237.0
HKD2_k127_8612241_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000202 230.0
HKD2_k127_8612241_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.000000000000000000000000000000000000000000000000000004732 211.0
HKD2_k127_8612241_5 Rhomboid family K09650 - 3.4.21.105 0.0000000000000000000000000000000000000000000000007978 183.0
HKD2_k127_8612241_6 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000005006 164.0
HKD2_k127_8612241_7 Pantothenate kinase K09680 - 2.7.1.33 0.00000000000000000000000000000000601 141.0
HKD2_k127_8612241_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000009927 130.0
HKD2_k127_8612241_9 Histidine kinase - - - 0.0000000000000000000000000005855 120.0
HKD2_k127_8638615_0 DEAD DEAH box K03724 - - 0.0 1187.0
HKD2_k127_8638615_1 NADPH quinone K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 438.0
HKD2_k127_8638615_10 Transcriptional regulatory protein, C terminal - - - 0.0000000000000007254 92.0
HKD2_k127_8638615_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 414.0
HKD2_k127_8638615_3 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 402.0
HKD2_k127_8638615_4 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000000000000003253 270.0
HKD2_k127_8638615_5 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000003536 222.0
HKD2_k127_8638615_6 DUF218 domain - - - 0.00000000000000000000000000000000006531 142.0
HKD2_k127_8638615_7 Methyltransferase domain - - - 0.0000000000000000000000001136 122.0
HKD2_k127_8638615_8 Translation initiation factor SUI1 K03113 - - 0.000000000000000000000001315 119.0
HKD2_k127_8638615_9 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.0000000000000000000002024 109.0
HKD2_k127_8671846_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) - - - 9.648e-230 732.0
HKD2_k127_8671846_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 484.0
HKD2_k127_8671846_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 454.0
HKD2_k127_8671846_3 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 457.0
HKD2_k127_8671846_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002021 303.0
HKD2_k127_8671846_5 HupE / UreJ protein - - - 0.0000000000000005106 86.0
HKD2_k127_8723372_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1118.0
HKD2_k127_8723372_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1050.0
HKD2_k127_8723372_10 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 285.0
HKD2_k127_8723372_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 286.0
HKD2_k127_8723372_12 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001314 263.0
HKD2_k127_8723372_13 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000765 258.0
HKD2_k127_8723372_14 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008166 267.0
HKD2_k127_8723372_15 alpha beta - - - 0.00000000000000000000000000000000000000000001982 183.0
HKD2_k127_8723372_16 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000002439 181.0
HKD2_k127_8723372_17 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000001033 167.0
HKD2_k127_8723372_18 GIY-YIG type nucleases (URI domain) K02342 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391 2.7.7.7 0.0000000000000000000000000000000001908 144.0
HKD2_k127_8723372_19 Membrane - - - 0.00000000000000000000000000000005259 138.0
HKD2_k127_8723372_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 9.197e-195 618.0
HKD2_k127_8723372_20 Phosphoglycerate mutase family - - - 0.0000000000000000000000008639 121.0
HKD2_k127_8723372_21 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000001537 121.0
HKD2_k127_8723372_22 SCP-2 sterol transfer family protein - - - 0.0002043 53.0
HKD2_k127_8723372_3 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 521.0
HKD2_k127_8723372_4 MviN-like protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 528.0
HKD2_k127_8723372_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 484.0
HKD2_k127_8723372_6 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 438.0
HKD2_k127_8723372_7 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 424.0
HKD2_k127_8723372_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 323.0
HKD2_k127_8723372_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 319.0
HKD2_k127_8741291_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 2.544e-222 707.0
HKD2_k127_8741291_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016625,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0047553,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 440.0
HKD2_k127_8741291_2 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000000000000000002497 214.0
HKD2_k127_8741291_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000001674 188.0
HKD2_k127_8741291_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000002203 175.0
HKD2_k127_8741291_5 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000001699 166.0
HKD2_k127_8741291_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000001326 137.0
HKD2_k127_8741291_7 Tetratricopeptide TPR_2 - - - 0.00000000000000000000009499 111.0
HKD2_k127_8741291_8 Helix-turn-helix domain - - - 0.00000000447 64.0
HKD2_k127_8746511_0 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 458.0
HKD2_k127_8746511_1 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 373.0
HKD2_k127_8746511_2 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 312.0
HKD2_k127_8746511_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001347 290.0
HKD2_k127_8746511_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000008357 228.0
HKD2_k127_8746511_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000344 183.0
HKD2_k127_8746511_6 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000002543 162.0
HKD2_k127_8746511_7 - - - - 0.0000000000000000000000004827 108.0
HKD2_k127_8746511_8 - - - - 0.0000000000000000002293 91.0
HKD2_k127_8746511_9 Adenylate cyclase - - - 0.0000000000000002087 84.0
HKD2_k127_8974614_0 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 471.0
HKD2_k127_8974614_1 enoyl-CoA hydratase isomerase family K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 398.0
HKD2_k127_8974614_10 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000006443 215.0
HKD2_k127_8974614_11 transporter component K07112 - - 0.00000000000000000000000000000000000000008747 154.0
HKD2_k127_8974614_12 transporter component K07112 - - 0.00000000000000000000000000000000000002976 159.0
HKD2_k127_8974614_13 AAA ATPase domain - - - 0.000000000000000003294 96.0
HKD2_k127_8974614_14 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000001445 81.0
HKD2_k127_8974614_15 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000001079 78.0
HKD2_k127_8974614_16 PFAM blue (type 1) copper domain protein - - - 0.0000000001756 69.0
HKD2_k127_8974614_17 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000002667 54.0
HKD2_k127_8974614_2 RHS protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 421.0
HKD2_k127_8974614_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 383.0
HKD2_k127_8974614_4 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 387.0
HKD2_k127_8974614_5 Nitrite and sulphite reductase 4Fe-4S K00366,K00381,K00392 - 1.7.7.1,1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 366.0
HKD2_k127_8974614_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 338.0
HKD2_k127_8974614_7 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 329.0
HKD2_k127_8974614_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 310.0
HKD2_k127_8974614_9 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002812 249.0
HKD2_k127_8978224_0 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 586.0
HKD2_k127_8978224_1 Thiolase, C-terminal domain K00626 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 599.0
HKD2_k127_8978224_10 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 350.0
HKD2_k127_8978224_11 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 331.0
HKD2_k127_8978224_12 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 347.0
HKD2_k127_8978224_13 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 302.0
HKD2_k127_8978224_14 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007452 266.0
HKD2_k127_8978224_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000001042 232.0
HKD2_k127_8978224_16 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000000001164 236.0
HKD2_k127_8978224_17 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000353 194.0
HKD2_k127_8978224_18 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000001248 183.0
HKD2_k127_8978224_19 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000338 149.0
HKD2_k127_8978224_2 Coenzyme PQQ synthesis protein D (PqqD) K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 575.0
HKD2_k127_8978224_20 - - - - 0.000000000006902 70.0
HKD2_k127_8978224_21 - - - - 0.0000000001243 77.0
HKD2_k127_8978224_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 548.0
HKD2_k127_8978224_4 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 515.0
HKD2_k127_8978224_5 protein secretion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 516.0
HKD2_k127_8978224_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 480.0
HKD2_k127_8978224_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 413.0
HKD2_k127_8978224_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 370.0
HKD2_k127_8978224_9 GAF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 361.0
HKD2_k127_9042224_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate - - - 2.514e-290 914.0
HKD2_k127_9042224_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.998e-283 888.0
HKD2_k127_9042224_10 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 304.0
HKD2_k127_9042224_11 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002463 294.0
HKD2_k127_9042224_12 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007187 271.0
HKD2_k127_9042224_13 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000003119 229.0
HKD2_k127_9042224_14 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000000000000000000000000000000000000004011 227.0
HKD2_k127_9042224_15 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000005769 201.0
HKD2_k127_9042224_16 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000002796 212.0
HKD2_k127_9042224_17 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000000008042 203.0
HKD2_k127_9042224_18 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000000000001128 192.0
HKD2_k127_9042224_19 - - - - 0.000000000000000000000000000000000000009904 151.0
HKD2_k127_9042224_2 iron-sulfur cluster assembly K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 3.957e-250 778.0
HKD2_k127_9042224_20 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000001715 138.0
HKD2_k127_9042224_21 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000002579 142.0
HKD2_k127_9042224_22 belongs to the aldehyde dehydrogenase family K03400 - 1.2.1.50 0.00000000000000000000004631 115.0
HKD2_k127_9042224_23 FIST N domain - - - 0.0000000000000000002335 102.0
HKD2_k127_9042224_24 Trypsin-like serine protease - - - 0.0000000000000000005488 96.0
HKD2_k127_9042224_25 Phosphoglycerate mutase family K02226,K22306 - 3.1.3.73,3.1.3.85 0.0000000000000000007015 102.0
HKD2_k127_9042224_26 Smr domain - - - 0.00000000000001949 78.0
HKD2_k127_9042224_27 PFAM NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000006123 79.0
HKD2_k127_9042224_28 Belongs to the universal stress protein A family - - - 0.0000003747 64.0
HKD2_k127_9042224_29 Lysylphosphatidylglycerol synthase TM region - - - 0.00009488 55.0
HKD2_k127_9042224_3 Aminoacyl-tRNA editing domain K01881 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 6.1.1.15 5.114e-227 721.0
HKD2_k127_9042224_30 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.000417 49.0
HKD2_k127_9042224_4 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 536.0
HKD2_k127_9042224_5 COG0006 Xaa-Pro aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 430.0
HKD2_k127_9042224_6 Acyl-CoA dehydrogenase, C-terminal domain K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 445.0
HKD2_k127_9042224_7 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 413.0
HKD2_k127_9042224_8 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 370.0
HKD2_k127_9042224_9 A G-specific K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 322.0
HKD2_k127_9101831_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.356e-245 773.0
HKD2_k127_9101831_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 573.0
HKD2_k127_9101831_11 cheY-homologous receiver domain - - - 0.00000000000000000000000001328 127.0
HKD2_k127_9101831_12 protein family UPF0079, ATPase K06925 - - 0.00000000000000000000007175 108.0
HKD2_k127_9101831_13 dehydratase - - - 0.0000000000000002123 91.0
HKD2_k127_9101831_15 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000002528 87.0
HKD2_k127_9101831_16 PFAM YbbR-like protein - - - 0.00000001263 64.0
HKD2_k127_9101831_17 cAMP biosynthetic process - - - 0.00000009581 62.0
HKD2_k127_9101831_2 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 506.0
HKD2_k127_9101831_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 440.0
HKD2_k127_9101831_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 385.0
HKD2_k127_9101831_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 374.0
HKD2_k127_9101831_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000006608 244.0
HKD2_k127_9101831_7 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000009769 247.0
HKD2_k127_9101831_8 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000005033 187.0
HKD2_k127_9101831_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000001962 155.0
HKD2_k127_9134895_0 hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001713 282.0
HKD2_k127_9134895_1 Putative porin - - - 0.00000000000001514 86.0
HKD2_k127_9137645_0 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 617.0
HKD2_k127_9137645_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 492.0
HKD2_k127_9137645_10 Belongs to the carbohydrate kinase PfkB family K00882,K00917 - 2.7.1.144,2.7.1.56 0.00000000000000000000000000000000000000002911 164.0
HKD2_k127_9137645_11 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000005594 171.0
HKD2_k127_9137645_12 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000001013 160.0
HKD2_k127_9137645_13 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000037 134.0
HKD2_k127_9137645_14 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.0000000000000000000000000000000003491 135.0
HKD2_k127_9137645_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000834 138.0
HKD2_k127_9137645_16 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000001507 131.0
HKD2_k127_9137645_17 heat shock protein binding - - - 0.000000000000000000000000001228 119.0
HKD2_k127_9137645_18 Cytochrome c554 and c-prime - - - 0.0000000000000000000005991 112.0
HKD2_k127_9137645_19 Cytochrome c554 and c-prime - - - 0.00000000000000000001694 107.0
HKD2_k127_9137645_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 440.0
HKD2_k127_9137645_20 there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc K02913 - - 0.00000000000000001695 89.0
HKD2_k127_9137645_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000004062 82.0
HKD2_k127_9137645_22 Redoxin - - - 0.0000146 58.0
HKD2_k127_9137645_23 lyase activity - - - 0.00002768 57.0
HKD2_k127_9137645_24 Tetratricopeptide repeat - - - 0.00003747 55.0
HKD2_k127_9137645_25 belongs to the thioredoxin family K03619,K05838 - - 0.0007238 54.0
HKD2_k127_9137645_3 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 307.0
HKD2_k127_9137645_4 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 301.0
HKD2_k127_9137645_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000001931 264.0
HKD2_k127_9137645_6 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000006661 241.0
HKD2_k127_9137645_7 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000995 233.0
HKD2_k127_9137645_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000001832 214.0
HKD2_k127_9137645_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000003847 186.0
HKD2_k127_9151601_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 428.0
HKD2_k127_9151601_1 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 376.0
HKD2_k127_9151601_2 PFAM response regulator receiver K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 292.0
HKD2_k127_9151601_3 Initiation factor 2 subunit family K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000001236 267.0
HKD2_k127_9151601_4 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000004129 227.0
HKD2_k127_9151601_5 PFAM Di-haem cytochrome c - - - 0.00000000000002488 74.0
HKD2_k127_9187545_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.35e-298 934.0
HKD2_k127_9187545_1 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 2.857e-246 771.0
HKD2_k127_9187545_10 PFAM Lectin C-type domain - - - 0.0000000000000000001682 104.0
HKD2_k127_9187545_11 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000000000006505 93.0
HKD2_k127_9187545_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K02182,K13776 - 6.2.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 606.0
HKD2_k127_9187545_3 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 582.0
HKD2_k127_9187545_4 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 365.0
HKD2_k127_9187545_5 Ring hydroxylating alpha subunit (catalytic domain) K22443 - 1.14.13.239 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 342.0
HKD2_k127_9187545_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000006935 217.0
HKD2_k127_9187545_8 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000000005637 164.0
HKD2_k127_9187545_9 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000002242 171.0
HKD2_k127_9215366_0 Acetyl-CoA hydrolase/transferase C-terminal domain K18288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 592.0
HKD2_k127_9215366_1 56kDa selenium binding protein (SBP56) K17285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 551.0
HKD2_k127_9215366_10 CBS domain - - - 0.000000575 62.0
HKD2_k127_9215366_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 474.0
HKD2_k127_9215366_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 420.0
HKD2_k127_9215366_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002802 278.0
HKD2_k127_9215366_5 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000152 259.0
HKD2_k127_9215366_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000005536 278.0
HKD2_k127_9215366_7 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007769 271.0
HKD2_k127_9215366_8 PFAM Di-heme cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000005729 169.0
HKD2_k127_9215366_9 Acyl-CoA dehydrogenase, type 2, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000077 87.0
HKD2_k127_9235902_0 COG2366 Protein related to penicillin acylase K01434,K07116 - 3.5.1.11,3.5.1.97 4.025e-199 655.0
HKD2_k127_9235902_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 479.0
HKD2_k127_9235902_10 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000691 236.0
HKD2_k127_9235902_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000005485 236.0
HKD2_k127_9235902_12 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000007573 207.0
HKD2_k127_9235902_13 ATPase associated with various cellular activities, AAA_5 K03924,K04748 - - 0.0000000000000000000000000000000000000000000000000001696 203.0
HKD2_k127_9235902_14 pfam nudix - - - 0.000000000000000000000000000000000000000000000000002819 194.0
HKD2_k127_9235902_15 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000003338 201.0
HKD2_k127_9235902_16 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000006436 199.0
HKD2_k127_9235902_17 COG0208 Ribonucleotide reductase, beta subunit - - - 0.00000000000000000000000000000000000000000000000007389 201.0
HKD2_k127_9235902_18 - - - - 0.000000000000000000000000000000000002226 148.0
HKD2_k127_9235902_2 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 477.0
HKD2_k127_9235902_20 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000006362 143.0
HKD2_k127_9235902_21 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000198 138.0
HKD2_k127_9235902_22 NUDIX domain - - - 0.00000000000000000000000000000003459 136.0
HKD2_k127_9235902_23 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000005145 123.0
HKD2_k127_9235902_24 membrane - - - 0.000000000000000000000002536 118.0
HKD2_k127_9235902_25 oxidoreductase activity K03924,K04748,K07114 - - 0.000000000000000003929 98.0
HKD2_k127_9235902_26 repeat protein - - - 0.00000000000001593 85.0
HKD2_k127_9235902_27 - - - - 0.00000000000498 76.0
HKD2_k127_9235902_28 - - - - 0.00000000001905 76.0
HKD2_k127_9235902_29 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00009452 55.0
HKD2_k127_9235902_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 441.0
HKD2_k127_9235902_30 ASCH - - - 0.0001147 45.0
HKD2_k127_9235902_4 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 417.0
HKD2_k127_9235902_5 Transposase IS116/IS110/IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 381.0
HKD2_k127_9235902_6 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 335.0
HKD2_k127_9235902_7 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 320.0
HKD2_k127_9235902_8 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 306.0
HKD2_k127_9235902_9 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000003433 250.0
HKD2_k127_9267431_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 450.0
HKD2_k127_9267431_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 416.0
HKD2_k127_9267431_10 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000001799 239.0
HKD2_k127_9267431_11 CYTH - - - 0.000000000000000000000000000000000000000000000000000000009776 207.0
HKD2_k127_9267431_12 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000009695 157.0
HKD2_k127_9267431_13 Methyltransferase type 12 - - - 0.000000000000000000000000000000000002084 148.0
HKD2_k127_9267431_14 Sh3 type 3 domain protein - - - 0.0000000000000429 87.0
HKD2_k127_9267431_15 Sh3 type 3 domain protein - - - 0.00000000001388 79.0
HKD2_k127_9267431_2 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 380.0
HKD2_k127_9267431_3 Repeat of Unknown Function (DUF347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 354.0
HKD2_k127_9267431_4 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 325.0
HKD2_k127_9267431_5 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 318.0
HKD2_k127_9267431_6 enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 299.0
HKD2_k127_9267431_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001937 295.0
HKD2_k127_9267431_8 alpha, beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000000005919 229.0
HKD2_k127_9267431_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000001211 220.0
HKD2_k127_9269566_0 PFAM tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 574.0
HKD2_k127_9269566_1 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 541.0
HKD2_k127_9269566_10 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 337.0
HKD2_k127_9269566_11 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 334.0
HKD2_k127_9269566_12 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002695 250.0
HKD2_k127_9269566_13 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000004725 231.0
HKD2_k127_9269566_14 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002 213.0
HKD2_k127_9269566_15 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000002518 188.0
HKD2_k127_9269566_16 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000008416 182.0
HKD2_k127_9269566_17 Pfam Uncharacterised ACR, YkgG family COG1556 K00782 - - 0.0000000000002265 84.0
HKD2_k127_9269566_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 485.0
HKD2_k127_9269566_3 Serine aminopeptidase, S33 K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 475.0
HKD2_k127_9269566_4 cluster binding protein K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 483.0
HKD2_k127_9269566_5 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009648 405.0
HKD2_k127_9269566_6 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 389.0
HKD2_k127_9269566_7 Carboxylesterase family K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 378.0
HKD2_k127_9269566_8 Cation transport protein K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 376.0
HKD2_k127_9269566_9 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 340.0
HKD2_k127_9304831_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 513.0
HKD2_k127_9304831_1 phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 516.0
HKD2_k127_9304831_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
HKD2_k127_9304831_3 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000002678 156.0
HKD2_k127_9304831_4 Putative porin - - - 0.000000000000000000009558 106.0
HKD2_k127_9448243_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1256.0
HKD2_k127_9448243_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1162.0
HKD2_k127_9448243_10 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 538.0
HKD2_k127_9448243_100 MORN repeat variant - - - 0.000000000005896 76.0
HKD2_k127_9448243_101 peptidyl-tyrosine sulfation - - - 0.00000000001852 77.0
HKD2_k127_9448243_102 HEAT repeats - - - 0.00000000007523 75.0
HKD2_k127_9448243_103 Domain of unknown function (DUF1844) - - - 0.0000000001593 73.0
HKD2_k127_9448243_104 - - - - 0.0000000001696 69.0
HKD2_k127_9448243_105 Uncharacterized conserved protein (DUF2304) K09153 - - 0.0000000004457 72.0
HKD2_k127_9448243_106 Pup-like protein K13570 - - 0.0000000008536 63.0
HKD2_k127_9448243_107 PFAM Lytic transglycosylase catalytic - - - 0.00000000216 66.0
HKD2_k127_9448243_108 SMART Tetratricopeptide repeat - - - 0.000000009584 69.0
HKD2_k127_9448243_109 - - - - 0.0000001138 59.0
HKD2_k127_9448243_11 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 554.0
HKD2_k127_9448243_110 SCP-2 sterol transfer family protein - - - 0.0000007405 62.0
HKD2_k127_9448243_111 Inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000002129 60.0
HKD2_k127_9448243_112 membrane protein, required for colicin V production K03558 - - 0.000004248 56.0
HKD2_k127_9448243_113 polysaccharide deacetylase - - - 0.00006079 55.0
HKD2_k127_9448243_12 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 533.0
HKD2_k127_9448243_13 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 526.0
HKD2_k127_9448243_14 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 526.0
HKD2_k127_9448243_15 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 514.0
HKD2_k127_9448243_16 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 485.0
HKD2_k127_9448243_17 Rod shape-determining protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 470.0
HKD2_k127_9448243_18 PFAM Glycosyl transferase, family 2 K11936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 466.0
HKD2_k127_9448243_19 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 462.0
HKD2_k127_9448243_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.046e-303 968.0
HKD2_k127_9448243_20 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 449.0
HKD2_k127_9448243_21 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 449.0
HKD2_k127_9448243_22 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 439.0
HKD2_k127_9448243_23 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 448.0
HKD2_k127_9448243_24 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 416.0
HKD2_k127_9448243_25 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 436.0
HKD2_k127_9448243_26 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 414.0
HKD2_k127_9448243_27 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 400.0
HKD2_k127_9448243_28 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 410.0
HKD2_k127_9448243_29 acyl-CoA dehydrogenase K14448 - 1.3.8.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 397.0
HKD2_k127_9448243_3 GMC oxidoreductase - - - 6.054e-233 784.0
HKD2_k127_9448243_30 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 381.0
HKD2_k127_9448243_31 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 352.0
HKD2_k127_9448243_32 Competence-damaged protein K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 315.0
HKD2_k127_9448243_33 Alanine-glyoxylate amino-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000142 295.0
HKD2_k127_9448243_34 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 278.0
HKD2_k127_9448243_35 Proteasome subunit K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006756 277.0
HKD2_k127_9448243_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001245 282.0
HKD2_k127_9448243_37 Protein conserved in bacteria K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000003081 280.0
HKD2_k127_9448243_38 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003268 275.0
HKD2_k127_9448243_39 oxidoreductase activity K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000001585 253.0
HKD2_k127_9448243_4 dipeptidyl-peptidase activity K06978 - - 1.488e-215 699.0
HKD2_k127_9448243_40 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005782 269.0
HKD2_k127_9448243_41 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002888 262.0
HKD2_k127_9448243_42 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000005811 246.0
HKD2_k127_9448243_43 Proteasome subunit K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000006231 258.0
HKD2_k127_9448243_44 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007372 267.0
HKD2_k127_9448243_45 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000001053 252.0
HKD2_k127_9448243_46 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000005794 229.0
HKD2_k127_9448243_47 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000001703 214.0
HKD2_k127_9448243_48 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000007615 214.0
HKD2_k127_9448243_49 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000001888 223.0
HKD2_k127_9448243_5 ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 7.753e-209 666.0
HKD2_k127_9448243_50 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000007277 225.0
HKD2_k127_9448243_51 proteins of the AP superfamily - - - 0.00000000000000000000000000000000000000000000000000000009597 215.0
HKD2_k127_9448243_52 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000001585 199.0
HKD2_k127_9448243_53 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000000000001819 192.0
HKD2_k127_9448243_55 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000000000000000000000000001571 186.0
HKD2_k127_9448243_56 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000002284 203.0
HKD2_k127_9448243_57 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000007101 179.0
HKD2_k127_9448243_58 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000001553 175.0
HKD2_k127_9448243_59 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000001478 183.0
HKD2_k127_9448243_6 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 598.0
HKD2_k127_9448243_60 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000001612 171.0
HKD2_k127_9448243_61 - - - - 0.000000000000000000000000000000000000000000001762 176.0
HKD2_k127_9448243_62 Domain of unknown function (DUF4336) - - - 0.000000000000000000000000000000000000000000003717 171.0
HKD2_k127_9448243_63 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000005186 176.0
HKD2_k127_9448243_64 Rhodanese - - - 0.000000000000000000000000000000000000000000005638 188.0
HKD2_k127_9448243_65 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000002951 169.0
HKD2_k127_9448243_66 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 GO:0000041,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0006826,GO:0008150,GO:0008152,GO:0008823,GO:0015677,GO:0015682,GO:0016020,GO:0016021,GO:0016491,GO:0016722,GO:0016723,GO:0030001,GO:0031224,GO:0031226,GO:0033216,GO:0034220,GO:0034755,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0052851,GO:0055085,GO:0055114,GO:0071944,GO:0072512,GO:0097286,GO:0098655,GO:0098657,GO:0098659,GO:0098660,GO:0098662,GO:0098706,GO:0098711,GO:0098739,GO:0099587 1.5.1.40 0.000000000000000000000000000000000000000000133 184.0
HKD2_k127_9448243_67 YCII-related domain - - - 0.0000000000000000000000000000000000000000001355 165.0
HKD2_k127_9448243_68 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000636 179.0
HKD2_k127_9448243_69 lipoprotein biosynthetic process K13292 - - 0.00000000000000000000000000000000000000002192 162.0
HKD2_k127_9448243_7 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 575.0
HKD2_k127_9448243_70 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000001397 169.0
HKD2_k127_9448243_71 - - - - 0.000000000000000000000000000000000000002142 169.0
HKD2_k127_9448243_72 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000001678 167.0
HKD2_k127_9448243_73 Inositol monophosphatase family K01092,K05602 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008934,GO:0009058,GO:0009987,GO:0010125,GO:0010126,GO:0016020,GO:0016053,GO:0016137,GO:0016138,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0052745,GO:0052803,GO:0052834,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000001564 160.0
HKD2_k127_9448243_74 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002003 142.0
HKD2_k127_9448243_75 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000006194 141.0
HKD2_k127_9448243_76 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000003042 136.0
HKD2_k127_9448243_77 - - - - 0.000000000000000000000000000000009932 147.0
HKD2_k127_9448243_78 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.000000000000000000000000000000871 128.0
HKD2_k127_9448243_79 peptidase C26 K01658,K07010 - 4.1.3.27 0.0000000000000000000000000000009815 138.0
HKD2_k127_9448243_8 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 582.0
HKD2_k127_9448243_80 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000001296 140.0
HKD2_k127_9448243_81 Outer membrane efflux protein K15725 - - 0.000000000000000000000000000008122 134.0
HKD2_k127_9448243_82 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000001912 129.0
HKD2_k127_9448243_83 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000004915 129.0
HKD2_k127_9448243_84 Protein of unknown function (DUF971) K03593 - - 0.000000000000000000000000001547 126.0
HKD2_k127_9448243_85 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000003644 117.0
HKD2_k127_9448243_86 4Fe-4S binding domain - - - 0.0000000000000000000000001035 117.0
HKD2_k127_9448243_87 phosphatase activity K07025 - - 0.000000000000000000000000177 117.0
HKD2_k127_9448243_88 lipid a biosynthesis - - - 0.0000000000000000000000002831 110.0
HKD2_k127_9448243_89 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.000000000000000000000002206 115.0
HKD2_k127_9448243_9 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 579.0
HKD2_k127_9448243_90 Amidohydrolase family - - - 0.000000000000000000000005895 104.0
HKD2_k127_9448243_91 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000002966 110.0
HKD2_k127_9448243_92 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000005907 106.0
HKD2_k127_9448243_93 - - - - 0.0000000000000000000003917 108.0
HKD2_k127_9448243_94 PilZ domain K02676 - - 0.000000000000000000002217 98.0
HKD2_k127_9448243_95 Predicted membrane protein (DUF2142) - - - 0.000000000000000000008829 108.0
HKD2_k127_9448243_96 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000005642 102.0
HKD2_k127_9448243_97 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000003029 99.0
HKD2_k127_9448243_98 - - - - 0.0000000000000001248 94.0
HKD2_k127_9448243_99 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000002057 84.0
HKD2_k127_9500736_0 Superfamily II DNA RNA helicases, SNF2 family - - - 1.079e-234 742.0
HKD2_k127_9500736_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 410.0
HKD2_k127_9500736_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 383.0
HKD2_k127_9500736_3 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004999 366.0
HKD2_k127_9500736_4 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 334.0
HKD2_k127_9500736_5 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000004881 193.0
HKD2_k127_9500736_6 Transposase - - - 0.0000000000000000000000000000000000000005584 162.0
HKD2_k127_9500736_7 protein heterodimerization activity - - - 0.0000000000000000000000000000000000000008028 154.0
HKD2_k127_9557383_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1062.0
HKD2_k127_9557383_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.00000000000000000000000000000000000000000000000000000000000000001781 258.0
HKD2_k127_9557383_2 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001426 222.0
HKD2_k127_9557383_3 transferase activity, transferring glycosyl groups - - - 0.000000001623 71.0
HKD2_k127_9600834_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1248.0
HKD2_k127_9600834_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 6.592e-230 732.0
HKD2_k127_9600834_10 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 346.0
HKD2_k127_9600834_11 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000006534 235.0
HKD2_k127_9600834_12 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000007079 226.0
HKD2_k127_9600834_13 PAC2 family - - - 0.0000000000000000000000000000000000000000000000000000001136 218.0
HKD2_k127_9600834_14 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.0000000000000000000000000000000000000000000000000005663 193.0
HKD2_k127_9600834_15 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000647 210.0
HKD2_k127_9600834_16 Pfam Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000001403 192.0
HKD2_k127_9600834_17 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000005018 175.0
HKD2_k127_9600834_18 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000009292 164.0
HKD2_k127_9600834_19 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000103 128.0
HKD2_k127_9600834_2 4Fe-4S dicluster domain K00184 - - 5.011e-215 704.0
HKD2_k127_9600834_20 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000002748 99.0
HKD2_k127_9600834_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000326 86.0
HKD2_k127_9600834_22 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000005187 82.0
HKD2_k127_9600834_23 PFAM Rhomboid family protein - - - 0.000000000000005551 88.0
HKD2_k127_9600834_24 Sh3 type 3 domain protein - - - 0.00000000000001042 89.0
HKD2_k127_9600834_25 Spore coat protein CotH K20276 - - 0.0000000000002761 82.0
HKD2_k127_9600834_26 Belongs to the P(II) protein family K04751 - - 0.000000001686 65.0
HKD2_k127_9600834_27 Transcription factor zinc-finger K09981 - - 0.00000001594 62.0
HKD2_k127_9600834_28 - - - - 0.000005316 56.0
HKD2_k127_9600834_29 Outer membrane lipoprotein-sorting protein - - - 0.000141 54.0
HKD2_k127_9600834_3 Bacterial DNA topoisomeraes I ATP-binding domain K03169 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 632.0
HKD2_k127_9600834_4 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 556.0
HKD2_k127_9600834_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 523.0
HKD2_k127_9600834_6 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 479.0
HKD2_k127_9600834_7 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 436.0
HKD2_k127_9600834_8 Histidyl-trna synthetase K01892,K14442 GO:0003674,GO:0003824,GO:0004812,GO:0004821,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006427,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009507,GO:0009536,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 3.6.4.13,6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 393.0
HKD2_k127_9600834_9 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 357.0
HKD2_k127_9710847_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1169.0
HKD2_k127_9710847_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.337e-205 650.0
HKD2_k127_9710847_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 335.0
HKD2_k127_9710847_3 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000004913 149.0
HKD2_k127_9710847_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000001459 159.0
HKD2_k127_9736325_0 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 625.0
HKD2_k127_9736325_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 493.0
HKD2_k127_9736325_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000007996 270.0
HKD2_k127_9736325_3 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000338 167.0
HKD2_k127_9736325_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000009304 171.0
HKD2_k127_9736325_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000297 150.0
HKD2_k127_9736325_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000002115 124.0
HKD2_k127_9736325_7 long-chain fatty acid transport protein - - - 0.000000000000006135 86.0
HKD2_k127_9796394_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001115 264.0
HKD2_k127_9796394_1 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000005991 237.0
HKD2_k127_9796394_2 Ferric reductase NAD binding domain K02613,K15983 - 1.14.13.142 0.000000000000000000000000000000000000000000000000001128 193.0
HKD2_k127_9796394_3 Bacterial regulatory proteins, tetR family K13770 - - 0.0000000000000000000000000000000000000001451 162.0
HKD2_k127_9796394_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000449 161.0
HKD2_k127_9796394_5 Glycosyl transferases group 1 K02844 - - 0.00000000000000000000000000000000001939 144.0
HKD2_k127_9796394_6 Domain of unknown function (DUF4340) - - - 0.000000000000000000000001828 118.0
HKD2_k127_9796394_7 Oxidoreductase FAD-binding domain - - - 0.0000000000000008983 78.0
HKD2_k127_9854283_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 9.062e-204 664.0
HKD2_k127_9854283_1 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 499.0
HKD2_k127_9854283_10 HlyD family secretion protein K01993 - - 0.0000000000000000000000000002573 133.0
HKD2_k127_9854283_11 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000004078 99.0
HKD2_k127_9854283_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 481.0
HKD2_k127_9854283_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 333.0
HKD2_k127_9854283_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 309.0
HKD2_k127_9854283_5 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 321.0
HKD2_k127_9854283_6 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000381 303.0
HKD2_k127_9854283_7 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001754 303.0
HKD2_k127_9854283_8 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003585 276.0
HKD2_k127_9854283_9 Binding-protein-dependent transport system inner membrane component K02050,K15599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001088 268.0
HKD2_k127_9866614_0 gluconolactonase activity K01053 - 3.1.1.17 7.989e-199 635.0
HKD2_k127_9866614_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 437.0
HKD2_k127_9866614_2 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000008121 160.0
HKD2_k127_9866614_3 Dicarboxylate transport - - - 0.000000000000000000000000000000002065 146.0
HKD2_k127_9866614_4 protein conserved in bacteria K09978 - - 0.00000000000000000006958 97.0
HKD2_k127_9866614_5 Thiol-disulfide oxidoreductase - - - 0.00000000000000005079 92.0
HKD2_k127_9866614_6 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000006262 66.0
HKD2_k127_9866614_7 YnbE-like lipoprotein - - - 0.00000000003088 76.0
HKD2_k127_9866614_8 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00007076 55.0
HKD2_k127_9881453_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 3.816e-254 819.0
HKD2_k127_9881453_1 HypF finger K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 451.0
HKD2_k127_9881453_2 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 404.0
HKD2_k127_9881453_3 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 402.0
HKD2_k127_9881453_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000006996 244.0
HKD2_k127_9881453_5 - - - - 0.000000000000000000000000000000000000000000000000000002898 204.0
HKD2_k127_9881453_6 CoA binding domain - - - 0.0000000000000000000000000000000001236 154.0
HKD2_k127_9883501_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 2.391e-268 884.0
HKD2_k127_9883501_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 7.36e-247 797.0
HKD2_k127_9883501_10 - - - - 0.000000000000001137 81.0
HKD2_k127_9883501_11 PeriplasmiC protein - - - 0.0000004922 60.0
HKD2_k127_9883501_2 Thiolase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 396.0
HKD2_k127_9883501_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 386.0
HKD2_k127_9883501_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 377.0
HKD2_k127_9883501_5 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001428 284.0
HKD2_k127_9883501_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000025 250.0
HKD2_k127_9883501_7 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000554 243.0
HKD2_k127_9883501_8 TLC ATP/ADP transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000007056 259.0
HKD2_k127_9883501_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000002273 106.0
HKD2_k127_9921416_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 639.0
HKD2_k127_9921416_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 498.0
HKD2_k127_9921416_10 protein maturation K13628 - - 0.000000000000000000000000204 109.0
HKD2_k127_9921416_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000007183 83.0
HKD2_k127_9921416_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000004991 72.0
HKD2_k127_9921416_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0000000001278 65.0
HKD2_k127_9921416_14 serine threonine protein kinase - - - 0.00001236 56.0
HKD2_k127_9921416_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 384.0
HKD2_k127_9921416_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 386.0
HKD2_k127_9921416_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 334.0
HKD2_k127_9921416_5 Catalyzes the synthesis of activated sulfate K00860 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016740,GO:0016772,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001571 279.0
HKD2_k127_9921416_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003421 263.0
HKD2_k127_9921416_7 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000008355 244.0
HKD2_k127_9921416_8 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000959 235.0
HKD2_k127_9921416_9 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000001788 211.0