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Overview

ID MAG01805
Name HKD2_bin.57
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus DASVZT01
Species
Assembly information
Completeness (%) 84.41
Contamination (%) 1.33
GC content (%) 72.0
N50 (bp) 9,438
Genome size (bp) 2,681,480

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2360

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10060252_0 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 544.0
HKD2_k127_1008154_0 Aminotransferase class-V - - - 4.221e-207 653.0
HKD2_k127_1008154_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 592.0
HKD2_k127_1008154_2 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 261.0
HKD2_k127_1008154_3 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001369 246.0
HKD2_k127_1008154_4 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000008397 249.0
HKD2_k127_1008154_5 Glycine cleavage system P-protein K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000001987 226.0
HKD2_k127_1008154_6 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000002762 149.0
HKD2_k127_1008154_7 - - - - 0.00000000000000000000000000018 122.0
HKD2_k127_1008409_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000004699 246.0
HKD2_k127_1008409_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000002715 162.0
HKD2_k127_1008409_2 SAF K02279 - - 0.00000000008089 74.0
HKD2_k127_1280750_0 Belongs to the peptidase S16 family - - - 1.229e-202 656.0
HKD2_k127_1280750_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 593.0
HKD2_k127_1280750_2 Acetylornithine deacetylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 309.0
HKD2_k127_1280750_3 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005252 274.0
HKD2_k127_1280750_4 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001292 240.0
HKD2_k127_1280750_5 TIGRFAM LPXTG-motif cell wall anchor domain - - - 0.0000000000000000000000000000000000000000001821 171.0
HKD2_k127_1280750_6 ABC-2 family transporter protein K01992 - - 0.00000000000009234 84.0
HKD2_k127_1280750_7 Phospholipase_D-nuclease N-terminal - - - 0.0000002041 63.0
HKD2_k127_1291556_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.863e-233 748.0
HKD2_k127_1291556_1 the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 514.0
HKD2_k127_1291556_10 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000000000003301 144.0
HKD2_k127_1291556_11 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000001951 143.0
HKD2_k127_1291556_12 TRANSCRIPTIONal - - - 0.000000000000000000000000001152 130.0
HKD2_k127_1291556_13 Pfam:DUF385 - - - 0.000000000000000000000001243 117.0
HKD2_k127_1291556_14 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.0000000000000000003661 99.0
HKD2_k127_1291556_15 DSBA-like thioredoxin domain - - - 0.0000000000000007242 87.0
HKD2_k127_1291556_16 PFAM amino acid-binding ACT domain protein - - - 0.000008046 56.0
HKD2_k127_1291556_2 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 425.0
HKD2_k127_1291556_3 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 359.0
HKD2_k127_1291556_4 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 367.0
HKD2_k127_1291556_5 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 327.0
HKD2_k127_1291556_6 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000003863 259.0
HKD2_k127_1291556_7 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000003921 229.0
HKD2_k127_1291556_8 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000001844 215.0
HKD2_k127_1291556_9 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000006367 194.0
HKD2_k127_1292052_0 Belongs to the proline racemase family K01777,K12658 - 5.1.1.4,5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 530.0
HKD2_k127_1292052_1 Urease alpha-subunit, N-terminal domain K01428 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 522.0
HKD2_k127_1292052_2 PFAM galactose-1-phosphate uridyl transferase domain protein K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000002834 247.0
HKD2_k127_1292052_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000002443 192.0
HKD2_k127_1292052_4 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.0000000000000000000000003438 111.0
HKD2_k127_1297069_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 543.0
HKD2_k127_1297069_1 DNA alkylation repair enzyme - - - 0.000000006397 65.0
HKD2_k127_1299621_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002262 299.0
HKD2_k127_1299621_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002067 297.0
HKD2_k127_1299621_2 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001796 248.0
HKD2_k127_1299621_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000003277 229.0
HKD2_k127_1299621_4 asparaginase activity K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000004797 226.0
HKD2_k127_1299621_5 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000003321 208.0
HKD2_k127_1299621_6 Bacterial protein of unknown function (DUF881) - - - 0.00000000000000000000003402 113.0
HKD2_k127_1299621_7 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000004604 102.0
HKD2_k127_1299621_8 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000142 85.0
HKD2_k127_1299621_9 - - - - 0.000000000001081 72.0
HKD2_k127_1321500_0 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 368.0
HKD2_k127_1321500_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001549 233.0
HKD2_k127_1321500_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000006103 219.0
HKD2_k127_1321500_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000006691 165.0
HKD2_k127_1321500_4 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000001837 126.0
HKD2_k127_1321500_5 COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair K03657 - 3.6.4.12 0.000000000000001142 88.0
HKD2_k127_1321500_8 - - - - 0.00001654 53.0
HKD2_k127_1338312_0 DEAD/H associated K03724 - - 0.0 1442.0
HKD2_k127_1338312_1 PFAM histone deacetylase superfamily K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 335.0
HKD2_k127_1338312_2 DoxX K16937 - 1.8.5.2 0.000000000000001751 86.0
HKD2_k127_1341948_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 4.699e-197 642.0
HKD2_k127_1341948_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 574.0
HKD2_k127_1341948_10 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000000000002017 76.0
HKD2_k127_1341948_11 Histidine kinase - - - 0.0000000006534 73.0
HKD2_k127_1341948_12 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000005273 59.0
HKD2_k127_1341948_2 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 491.0
HKD2_k127_1341948_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 463.0
HKD2_k127_1341948_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 340.0
HKD2_k127_1341948_5 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 330.0
HKD2_k127_1341948_6 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000002205 239.0
HKD2_k127_1341948_7 AAA domain - - - 0.000000000000000000000003512 112.0
HKD2_k127_1341948_8 SpoIIAA-like - - - 0.0000000000000000002808 92.0
HKD2_k127_1341948_9 spore germination K03605 - - 0.0000000000000000006931 94.0
HKD2_k127_1345408_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 412.0
HKD2_k127_1345408_1 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 363.0
HKD2_k127_1345408_10 DinB family - - - 0.0000000000000001136 93.0
HKD2_k127_1345408_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 308.0
HKD2_k127_1345408_3 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002538 282.0
HKD2_k127_1345408_4 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000002029 258.0
HKD2_k127_1345408_5 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001434 231.0
HKD2_k127_1345408_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000009116 232.0
HKD2_k127_1345408_7 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000009318 199.0
HKD2_k127_1345408_8 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.000000000000000000000000000002224 131.0
HKD2_k127_1345408_9 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.000000000000000000002838 104.0
HKD2_k127_1359659_0 ribonucleoside-diphosphate reductase activity K00525 - 1.17.4.1 8.456e-216 686.0
HKD2_k127_1359659_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 539.0
HKD2_k127_1359659_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000001832 248.0
HKD2_k127_1359659_11 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000001507 230.0
HKD2_k127_1359659_12 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000002115 228.0
HKD2_k127_1359659_13 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000003188 223.0
HKD2_k127_1359659_14 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000003889 218.0
HKD2_k127_1359659_15 Ketopantoate reductase - - - 0.00000000000000000000000000000000000000000000000006008 198.0
HKD2_k127_1359659_16 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000001803 174.0
HKD2_k127_1359659_17 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000008662 164.0
HKD2_k127_1359659_18 aminopeptidase N - - - 0.0000000000000000000000000000000000000000009451 181.0
HKD2_k127_1359659_19 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000001707 160.0
HKD2_k127_1359659_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 531.0
HKD2_k127_1359659_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000001114 150.0
HKD2_k127_1359659_21 Pfam:DUF2029 - - - 0.000000000000000000000000000000000003713 154.0
HKD2_k127_1359659_22 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000001392 136.0
HKD2_k127_1359659_23 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000009934 127.0
HKD2_k127_1359659_24 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000001317 130.0
HKD2_k127_1359659_25 Peptidase M23 K21471 - - 0.00000000000000000000000001859 124.0
HKD2_k127_1359659_26 - - - - 0.00000000000000000000002093 102.0
HKD2_k127_1359659_27 Tetratricopeptide repeat - - - 0.0000000000002998 83.0
HKD2_k127_1359659_28 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.000000000132 70.0
HKD2_k127_1359659_3 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 485.0
HKD2_k127_1359659_4 Nucleotidyl transferase K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 483.0
HKD2_k127_1359659_5 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 453.0
HKD2_k127_1359659_6 COG COG0531 Amino acid transporters Amino acid transport and metabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 464.0
HKD2_k127_1359659_7 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 401.0
HKD2_k127_1359659_8 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 321.0
HKD2_k127_1359659_9 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009355 289.0
HKD2_k127_1377305_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005094 274.0
HKD2_k127_1377305_1 Ribosomal protein S3, C-terminal domain K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004723 222.0
HKD2_k127_1377305_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000032 209.0
HKD2_k127_1377305_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000007371 190.0
HKD2_k127_1377305_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000001278 173.0
HKD2_k127_1377305_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000005855 120.0
HKD2_k127_1377305_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000002013 107.0
HKD2_k127_1377305_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000002064 92.0
HKD2_k127_1377305_8 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0002564 48.0
HKD2_k127_1378740_0 protein involved in exopolysaccharide biosynthesis - - - 7.481e-209 671.0
HKD2_k127_1378740_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 563.0
HKD2_k127_1378740_2 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 435.0
HKD2_k127_1378740_3 ABC transporter, ATP-binding protein K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 355.0
HKD2_k127_1378740_4 Belongs to the xylose isomerase family K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 305.0
HKD2_k127_1378740_5 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 320.0
HKD2_k127_1378740_6 TIGRFAM D-xylose ABC transporter K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 299.0
HKD2_k127_1378740_7 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000196 286.0
HKD2_k127_1378740_8 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001659 276.0
HKD2_k127_141445_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 426.0
HKD2_k127_141445_1 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000005542 278.0
HKD2_k127_141445_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000003327 140.0
HKD2_k127_141445_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000306 130.0
HKD2_k127_141445_12 Ribosomal protein L30p/L7e K02907 - - 0.0000000000001134 74.0
HKD2_k127_141445_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009902 70.0
HKD2_k127_141445_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002948 264.0
HKD2_k127_141445_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000002286 246.0
HKD2_k127_141445_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000123 240.0
HKD2_k127_141445_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000004845 223.0
HKD2_k127_141445_6 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
HKD2_k127_141445_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000004503 206.0
HKD2_k127_141445_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000006014 200.0
HKD2_k127_141445_9 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000003059 143.0
HKD2_k127_1429005_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000009624 233.0
HKD2_k127_1429005_1 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000003261 217.0
HKD2_k127_1429005_2 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.0000000000000000000000000000000000000004018 160.0
HKD2_k127_1429005_3 DNA binding domain - - - 0.0000000000000000000000000000001436 130.0
HKD2_k127_1429005_4 Domain of unknown function (DUF4332) - - - 0.000000000000000000000000000000365 136.0
HKD2_k127_1429005_5 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000007062 124.0
HKD2_k127_1429005_6 methyltransferase activity - - - 0.0000000000008507 78.0
HKD2_k127_1432312_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 377.0
HKD2_k127_1432312_1 acetyltransferase - - - 0.0000001056 61.0
HKD2_k127_1433979_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 303.0
HKD2_k127_1433979_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004706 259.0
HKD2_k127_1433979_2 EamA-like transporter family K11939 - - 0.000000000000000000000000000000000000000000000000000000001371 213.0
HKD2_k127_1449599_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 391.0
HKD2_k127_1449599_1 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 361.0
HKD2_k127_1449599_2 UDP-N-acetylglucosamine 2-epimerase activity K01791,K13019 - 5.1.3.14,5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 303.0
HKD2_k127_1449599_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000001247 271.0
HKD2_k127_1449599_4 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005488 257.0
HKD2_k127_1449599_5 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000004049 212.0
HKD2_k127_1449599_6 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000000000000000000000000000000000001465 201.0
HKD2_k127_1452634_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 457.0
HKD2_k127_1452634_1 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 393.0
HKD2_k127_1452634_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000002248 248.0
HKD2_k127_1453548_0 ResB-like family - - - 0.00000000000000000000000000000000000000000005409 178.0
HKD2_k127_1469236_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 358.0
HKD2_k127_1469236_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000007471 159.0
HKD2_k127_1469236_2 DNA methylAse K01155 - 3.1.21.4 0.00003625 57.0
HKD2_k127_1490413_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 617.0
HKD2_k127_1490413_1 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 297.0
HKD2_k127_1490413_10 - - - - 0.000000000002366 74.0
HKD2_k127_1490413_2 NmrA-like family K19267 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000001526 241.0
HKD2_k127_1490413_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000002474 217.0
HKD2_k127_1490413_4 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000006799 208.0
HKD2_k127_1490413_5 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000000002134 162.0
HKD2_k127_1490413_6 EVE domain - - - 0.000000000000000000000000000000000000268 152.0
HKD2_k127_1490413_7 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000001853 143.0
HKD2_k127_1490413_8 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000001617 141.0
HKD2_k127_1490413_9 Putative sensor - - - 0.000000000000000000000000001119 113.0
HKD2_k127_150193_0 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001253 259.0
HKD2_k127_150193_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000003278 164.0
HKD2_k127_150193_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000005551 134.0
HKD2_k127_150193_3 asnC family K03719 - - 0.000000000000000000000000000003886 125.0
HKD2_k127_150193_4 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000003 101.0
HKD2_k127_150193_5 Anti-sigma K factor RskA - - - 0.00005234 55.0
HKD2_k127_1504300_0 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000002058 186.0
HKD2_k127_1504300_2 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000001091 126.0
HKD2_k127_1504300_3 - - - - 0.00004835 51.0
HKD2_k127_150567_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 494.0
HKD2_k127_150567_1 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000001038 151.0
HKD2_k127_1516291_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 445.0
HKD2_k127_1516291_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 419.0
HKD2_k127_1516291_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 355.0
HKD2_k127_1516291_3 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000612 264.0
HKD2_k127_1516291_4 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000003674 199.0
HKD2_k127_1520884_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 454.0
HKD2_k127_1524757_0 Mannitol dehydrogenase C-terminal domain K00040,K00045 - 1.1.1.57,1.1.1.67 2.169e-231 727.0
HKD2_k127_1524757_1 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001013 252.0
HKD2_k127_1524757_2 Lysine methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.00000000000000001587 86.0
HKD2_k127_1524757_3 translation initiation factor activity - - - 0.0006581 50.0
HKD2_k127_1528832_0 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.0000000000000000000000000000000000211 140.0
HKD2_k127_1528832_1 ATPases associated with a variety of cellular activities K02003 - - 0.0000000004921 60.0
HKD2_k127_1535962_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 601.0
HKD2_k127_1535962_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 385.0
HKD2_k127_1535962_10 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000000002265 93.0
HKD2_k127_1535962_11 Tetratricopeptide TPR_2 repeat protein - - - 0.00000728 58.0
HKD2_k127_1535962_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005478 275.0
HKD2_k127_1535962_3 DisA bacterial checkpoint controller nucleotide-binding K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000000001491 210.0
HKD2_k127_1535962_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000004248 214.0
HKD2_k127_1535962_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000001068 183.0
HKD2_k127_1535962_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000007036 171.0
HKD2_k127_1535962_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000006441 176.0
HKD2_k127_1535962_8 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000001313 126.0
HKD2_k127_1535962_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000002592 119.0
HKD2_k127_1543867_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 400.0
HKD2_k127_1543867_1 Exporter of polyketide antibiotics K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 385.0
HKD2_k127_1543867_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000001568 181.0
HKD2_k127_1543867_3 EamA-like transporter family - - - 0.0000000000000000000000000000004955 132.0
HKD2_k127_1546068_0 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 614.0
HKD2_k127_1546068_1 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000000000000000000003487 154.0
HKD2_k127_1546068_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000002452 134.0
HKD2_k127_1546068_3 Diacylglycerol kinase K19302 - 3.6.1.27 0.000000000000000000000000002177 130.0
HKD2_k127_1546068_4 - - - - 0.00000000000000000000004855 100.0
HKD2_k127_1546068_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000002274 86.0
HKD2_k127_1546068_6 - - - - 0.0000298 57.0
HKD2_k127_1547453_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 356.0
HKD2_k127_1547453_1 - - - - 0.00000000000000000000000003698 117.0
HKD2_k127_1547453_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000003234 83.0
HKD2_k127_156224_0 Carbamoyl-phosphate synthase K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 3.848e-285 919.0
HKD2_k127_156224_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000003762 166.0
HKD2_k127_1578727_0 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000007616 207.0
HKD2_k127_1628615_0 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 363.0
HKD2_k127_1628615_1 Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family - - - 0.000000000000000000000000000000000000000001159 165.0
HKD2_k127_1628615_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000006316 157.0
HKD2_k127_16778_0 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000004056 152.0
HKD2_k127_16778_1 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000000000000000000509 137.0
HKD2_k127_1713797_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000001572 123.0
HKD2_k127_1763725_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 418.0
HKD2_k127_1763725_1 PspC domain K03973 - - 0.000000000009022 77.0
HKD2_k127_1763725_2 Putative adhesin - - - 0.000002684 59.0
HKD2_k127_1771512_0 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001791 278.0
HKD2_k127_1771512_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000001843 239.0
HKD2_k127_1771512_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000002419 227.0
HKD2_k127_1771512_3 NMT1/THI5 like K02051 - - 0.00000006443 66.0
HKD2_k127_1829258_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 524.0
HKD2_k127_1829258_1 Alanine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 332.0
HKD2_k127_1829258_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000003667 222.0
HKD2_k127_1829258_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000141 205.0
HKD2_k127_1829258_4 AMMECR1 K09141 - - 0.000000000000000000000000000000001081 139.0
HKD2_k127_1829258_5 Sigma-70, region 4 K03088 - - 0.0001071 44.0
HKD2_k127_1843875_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 353.0
HKD2_k127_1843875_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000001124 184.0
HKD2_k127_1843875_2 Putative glycolipid-binding - - - 0.0000000000000000000000000000000000000000347 158.0
HKD2_k127_1843875_3 - - - - 0.0000000000000000000000000000000000000001886 152.0
HKD2_k127_1843875_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000002668 158.0
HKD2_k127_1843875_5 - - - - 0.0000000000000000000000000000001271 134.0
HKD2_k127_1843875_6 Protein of unknown function (DUF4232) - - - 0.000000000000000004886 94.0
HKD2_k127_1843875_8 - - - - 0.0000005956 57.0
HKD2_k127_1843875_9 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.000009705 49.0
HKD2_k127_1890535_0 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 401.0
HKD2_k127_1890535_1 PFAM Adenosine AMP deaminase K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 357.0
HKD2_k127_1891282_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003792 264.0
HKD2_k127_1891282_1 Cyclic nucleotide-binding domain - - - 0.0000000000000000000001794 109.0
HKD2_k127_189759_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 326.0
HKD2_k127_189759_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 339.0
HKD2_k127_189759_2 Domain of unknown function (DUF4342) - - - 0.00000000000000000001446 97.0
HKD2_k127_189759_3 PspC domain K03973 - - 0.000000000001068 74.0
HKD2_k127_189759_4 PFAM blue (type 1) copper domain protein - - - 0.00002766 52.0
HKD2_k127_1968962_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 418.0
HKD2_k127_1968962_1 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 380.0
HKD2_k127_1968962_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
HKD2_k127_1968962_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000268 274.0
HKD2_k127_1968962_4 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000008023 74.0
HKD2_k127_2021579_0 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 432.0
HKD2_k127_2021579_1 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000000000000001667 159.0
HKD2_k127_2021579_2 - - - - 0.0000000000004377 74.0
HKD2_k127_2064136_0 von Willebrand factor type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
HKD2_k127_2064136_2 ABC-2 family transporter protein - - - 0.0000305 55.0
HKD2_k127_21277_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 2.217e-223 706.0
HKD2_k127_21277_1 PFAM MMPL domain protein K06994 - - 5.641e-197 640.0
HKD2_k127_21277_10 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000001077 155.0
HKD2_k127_21277_11 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000002027 154.0
HKD2_k127_21277_12 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000716 112.0
HKD2_k127_21277_13 transcriptional regulator, Rrf2 family - - - 0.00000000000000000002146 103.0
HKD2_k127_21277_14 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000004389 104.0
HKD2_k127_21277_15 transcriptional regulator, Rrf2 family - - - 0.0000000000000000001446 100.0
HKD2_k127_21277_16 Pfam:DUF59 - - - 0.000000000001177 72.0
HKD2_k127_21277_17 Protein of unknown function (DUF433) - - - 0.0003437 49.0
HKD2_k127_21277_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 545.0
HKD2_k127_21277_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 366.0
HKD2_k127_21277_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 355.0
HKD2_k127_21277_5 COG0147 Anthranilate para-aminobenzoate synthases component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 340.0
HKD2_k127_21277_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 317.0
HKD2_k127_21277_7 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001569 277.0
HKD2_k127_21277_8 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000004955 211.0
HKD2_k127_21277_9 Belongs to the BI1 family K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000001102 162.0
HKD2_k127_213662_0 Belongs to the ABC transporter superfamily K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 420.0
HKD2_k127_213662_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 435.0
HKD2_k127_213662_2 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 386.0
HKD2_k127_213662_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 353.0
HKD2_k127_213662_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 343.0
HKD2_k127_213662_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 315.0
HKD2_k127_213662_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000941 276.0
HKD2_k127_213662_7 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000002215 180.0
HKD2_k127_220843_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 2.2e-254 804.0
HKD2_k127_220843_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 449.0
HKD2_k127_220843_10 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000001538 137.0
HKD2_k127_220843_11 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000003782 126.0
HKD2_k127_220843_12 EamA-like transporter family - - - 0.0000000000000000000001295 110.0
HKD2_k127_220843_2 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 412.0
HKD2_k127_220843_3 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 372.0
HKD2_k127_220843_4 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007356 279.0
HKD2_k127_220843_5 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000001764 229.0
HKD2_k127_220843_6 triosephosphate isomerase K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000001979 215.0
HKD2_k127_220843_7 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000003198 185.0
HKD2_k127_220843_8 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000003628 166.0
HKD2_k127_220843_9 Belongs to the carbohydrate kinase PfkB family - - - 0.00000000000000000000000000000000005973 147.0
HKD2_k127_230401_0 E1-E2 ATPase K01537,K12953 - 3.6.3.8 2.245e-312 979.0
HKD2_k127_230401_1 - - - - 0.00000000007246 66.0
HKD2_k127_23288_0 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000001983 176.0
HKD2_k127_23288_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000006947 163.0
HKD2_k127_23288_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000004878 64.0
HKD2_k127_234328_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.529e-196 632.0
HKD2_k127_234328_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 441.0
HKD2_k127_234328_10 coenzyme F420 binding - - - 0.000000000000000000000000000000000001115 154.0
HKD2_k127_234328_11 DinB superfamily - - - 0.0000000000000000000000000000000000106 157.0
HKD2_k127_234328_12 domain protein K03709 - - 0.0000000000000000000000000000000637 144.0
HKD2_k127_234328_14 glyoxalase III activity - - - 0.000000000000000000000000007481 121.0
HKD2_k127_234328_15 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000001601 117.0
HKD2_k127_234328_16 heat shock protein binding K03686,K05516 - - 0.0000000001281 74.0
HKD2_k127_234328_2 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 441.0
HKD2_k127_234328_3 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 344.0
HKD2_k127_234328_4 response regulator K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000242 265.0
HKD2_k127_234328_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001003 239.0
HKD2_k127_234328_6 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000331 209.0
HKD2_k127_234328_7 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000005965 194.0
HKD2_k127_234328_8 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000007788 211.0
HKD2_k127_234328_9 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000007475 148.0
HKD2_k127_2370835_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1037.0
HKD2_k127_2370835_1 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 380.0
HKD2_k127_2370835_10 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000004267 103.0
HKD2_k127_2370835_11 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000005399 77.0
HKD2_k127_2370835_12 MobA-related protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000001975 72.0
HKD2_k127_2370835_13 Anti-sigma K factor RskA - - - 0.00000008022 65.0
HKD2_k127_2370835_14 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000003081 63.0
HKD2_k127_2370835_2 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001138 300.0
HKD2_k127_2370835_3 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001032 269.0
HKD2_k127_2370835_4 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000008784 228.0
HKD2_k127_2370835_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000001068 230.0
HKD2_k127_2370835_6 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000002713 217.0
HKD2_k127_2370835_7 'Molybdopterin - - - 0.00000000000000000000000000000000000000000003917 176.0
HKD2_k127_2370835_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000001395 158.0
HKD2_k127_2370835_9 Rhomboid family K19225 - 3.4.21.105 0.00000000000000000000000000001189 133.0
HKD2_k127_253375_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 410.0
HKD2_k127_253375_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 401.0
HKD2_k127_253375_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 362.0
HKD2_k127_253375_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 364.0
HKD2_k127_253375_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000001283 217.0
HKD2_k127_253375_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000004426 201.0
HKD2_k127_253375_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000147 183.0
HKD2_k127_2575055_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 427.0
HKD2_k127_2575055_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 300.0
HKD2_k127_2575055_2 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K04091 - 1.14.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000636 277.0
HKD2_k127_2575055_3 ArsC family - - - 0.00000000000000000000000000000003157 130.0
HKD2_k127_2575055_4 Rieske 2Fe-2S iron-sulphur domain K05710,K14750 - - 0.000000000006578 74.0
HKD2_k127_2575055_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000001072 74.0
HKD2_k127_2575055_6 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.0000000611 63.0
HKD2_k127_2590165_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000082 179.0
HKD2_k127_2590165_1 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000002614 153.0
HKD2_k127_2590165_2 NUDIX hydrolase - - - 0.0000000000000000000000000000004943 136.0
HKD2_k127_260798_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 329.0
HKD2_k127_260798_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000001415 184.0
HKD2_k127_260798_2 Archease protein family (MTH1598/TM1083) - - - 0.00001179 55.0
HKD2_k127_2616341_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 582.0
HKD2_k127_2616341_1 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 303.0
HKD2_k127_2616341_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006954 281.0
HKD2_k127_2616341_3 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HKD2_k127_2616341_4 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000006991 209.0
HKD2_k127_2616341_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000001639 72.0
HKD2_k127_2634787_0 Belongs to the sigma-70 factor family. ECF subfamily - - - 7.878e-194 614.0
HKD2_k127_2634787_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 382.0
HKD2_k127_2634787_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004028 263.0
HKD2_k127_2634787_3 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000000000004483 220.0
HKD2_k127_2634787_4 PFAM Cupin - - - 0.000000000000000000000000000000000001694 145.0
HKD2_k127_2634787_5 YCII-related domain - - - 0.0000000000000000000000001996 111.0
HKD2_k127_2634787_6 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.0000000000000000000004358 107.0
HKD2_k127_2641364_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1032.0
HKD2_k127_2641364_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 498.0
HKD2_k127_2644406_0 tRNA synthetases class II (D, K and N) K09759 - 6.1.1.23 1.723e-234 733.0
HKD2_k127_2644406_1 Voltage gated chloride channel K03281 - - 1.394e-196 638.0
HKD2_k127_2644406_11 Cold shock K03704 - - 0.0000000002066 65.0
HKD2_k127_2644406_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.00002518 55.0
HKD2_k127_2644406_13 amine dehydrogenase activity - - - 0.00005972 45.0
HKD2_k127_2644406_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 385.0
HKD2_k127_2644406_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 379.0
HKD2_k127_2644406_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000002689 211.0
HKD2_k127_2644406_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000003185 196.0
HKD2_k127_2644406_6 amine dehydrogenase activity K09815 - - 0.00000000000000000000000000000000000000000000004588 184.0
HKD2_k127_2644406_7 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000005066 179.0
HKD2_k127_2644406_8 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000004912 149.0
HKD2_k127_2644406_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000002092 149.0
HKD2_k127_2665354_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0 1097.0
HKD2_k127_2665354_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 451.0
HKD2_k127_2665354_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000009688 188.0
HKD2_k127_2665354_11 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000007391 179.0
HKD2_k127_2665354_12 Cellulose biosynthesis protein BcsQ K02282 - - 0.00000000000000000000000000000000000000004715 169.0
HKD2_k127_2665354_13 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000001669 149.0
HKD2_k127_2665354_14 DAK2 domain fusion protein YloV K07030 - - 0.00000000000000000000000000000000006194 141.0
HKD2_k127_2665354_15 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000006297 143.0
HKD2_k127_2665354_16 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000002564 115.0
HKD2_k127_2665354_17 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963,K03111,K15125 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001038 108.0
HKD2_k127_2665354_18 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000005728 97.0
HKD2_k127_2665354_19 Ribosomal L28 family K02902 - - 0.000000009053 58.0
HKD2_k127_2665354_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 338.0
HKD2_k127_2665354_20 Protein conserved in bacteria - - - 0.0001602 53.0
HKD2_k127_2665354_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005337 304.0
HKD2_k127_2665354_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009635 282.0
HKD2_k127_2665354_5 PFAM Sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001368 283.0
HKD2_k127_2665354_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000007793 216.0
HKD2_k127_2665354_7 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000006908 202.0
HKD2_k127_2665354_8 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000001018 214.0
HKD2_k127_2665354_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000008018 211.0
HKD2_k127_2676585_0 PFAM BMC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 300.0
HKD2_k127_2676585_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000434 264.0
HKD2_k127_2676585_2 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000000001792 190.0
HKD2_k127_2676585_3 BMC K04027 - - 0.00000000000000000000000000000000002438 141.0
HKD2_k127_2676585_4 Transcriptional regulator - - - 0.00000000000000000000000000000000003186 138.0
HKD2_k127_2677513_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 359.0
HKD2_k127_2698291_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 4.365e-226 716.0
HKD2_k127_2698291_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 481.0
HKD2_k127_2698291_10 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000001924 130.0
HKD2_k127_2698291_11 CAAX protease self-immunity K07052 - - 0.0000000000000000000000002086 123.0
HKD2_k127_2698291_12 Cobalamin B12-binding domain - - - 0.0000000000000005735 87.0
HKD2_k127_2698291_13 pyridoxamine 5-phosphate K07005 - - 0.000000000000005465 81.0
HKD2_k127_2698291_14 acetyltransferase - - - 0.00000000003832 74.0
HKD2_k127_2698291_15 Acetyltransferase (GNAT) domain - - - 0.0000000002118 67.0
HKD2_k127_2698291_17 Wyosine base formation K21167 - - 0.0001588 51.0
HKD2_k127_2698291_2 PFAM Lipopolysaccharide kinase (Kdo WaaP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 419.0
HKD2_k127_2698291_3 sequence-specific DNA binding K00567,K13529,K15051 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000002103 258.0
HKD2_k127_2698291_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000003246 218.0
HKD2_k127_2698291_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000003316 203.0
HKD2_k127_2698291_6 Nitroreductase family - - - 0.000000000000000000000000000000000003556 146.0
HKD2_k127_2698291_7 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000002079 144.0
HKD2_k127_2698291_8 Methyltransferase type 11 - - - 0.00000000000000000000000000000000474 142.0
HKD2_k127_2698291_9 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000001546 138.0
HKD2_k127_2724565_0 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 306.0
HKD2_k127_2724565_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000008223 203.0
HKD2_k127_2724565_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000001536 116.0
HKD2_k127_2724565_3 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000009842 87.0
HKD2_k127_2724565_4 DnaJ C terminal domain K03686 - - 0.000000000001622 78.0
HKD2_k127_2741598_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 323.0
HKD2_k127_2741598_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 319.0
HKD2_k127_2741598_2 PFAM CobB CobQ domain protein glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 276.0
HKD2_k127_2741598_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000002195 223.0
HKD2_k127_2741598_4 Domain of unknown function (DUF1727) - - - 0.000000000000000000000000000000000000000000000005636 177.0
HKD2_k127_2741598_5 - - - - 0.000001114 55.0
HKD2_k127_2745432_0 ABC transporter, transmembrane region K06147 - - 8.175e-227 715.0
HKD2_k127_2745432_1 ABC transporter, transmembrane region K06147 - - 3.189e-197 655.0
HKD2_k127_2757432_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1082.0
HKD2_k127_2757432_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 446.0
HKD2_k127_2757432_10 YceI-like domain - - - 0.000000000000000000000000000000000000000000002237 171.0
HKD2_k127_2757432_11 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000004562 181.0
HKD2_k127_2757432_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000001003 149.0
HKD2_k127_2757432_13 Luciferase-like monooxygenase - - - 0.000000000000000000000000000001218 130.0
HKD2_k127_2757432_14 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000009331 127.0
HKD2_k127_2757432_15 Cupin domain - - - 0.0000000000000000000000002253 123.0
HKD2_k127_2757432_16 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000001816 81.0
HKD2_k127_2757432_2 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 390.0
HKD2_k127_2757432_3 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 332.0
HKD2_k127_2757432_4 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002247 256.0
HKD2_k127_2757432_5 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000000002926 211.0
HKD2_k127_2757432_6 PFAM isochorismatase hydrolase K08281 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564 3.5.1.19 0.000000000000000000000000000000000000000000000000000000008476 205.0
HKD2_k127_2757432_7 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000001115 191.0
HKD2_k127_2757432_8 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000002026 195.0
HKD2_k127_2757432_9 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000001565 175.0
HKD2_k127_2759435_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 476.0
HKD2_k127_2759435_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 321.0
HKD2_k127_2759435_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000003644 117.0
HKD2_k127_2774034_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 319.0
HKD2_k127_2774034_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000002246 183.0
HKD2_k127_2774034_2 - - - - 0.000000000000000000002192 102.0
HKD2_k127_2781492_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1042.0
HKD2_k127_2781492_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416,K21417 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 604.0
HKD2_k127_2781492_10 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 312.0
HKD2_k127_2781492_11 ABC-type sugar transport system, permease component K10229 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 307.0
HKD2_k127_2781492_12 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 294.0
HKD2_k127_2781492_13 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 280.0
HKD2_k127_2781492_14 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009794 261.0
HKD2_k127_2781492_15 Belongs to the peptidase S51 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004698 237.0
HKD2_k127_2781492_16 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000002752 255.0
HKD2_k127_2781492_17 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000635 172.0
HKD2_k127_2781492_18 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000003393 154.0
HKD2_k127_2781492_19 Oxidoreductase FAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000005435 134.0
HKD2_k127_2781492_2 ABC-type sugar transport system, periplasmic component K02027,K10227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 452.0
HKD2_k127_2781492_20 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.00000000002216 77.0
HKD2_k127_2781492_3 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 433.0
HKD2_k127_2781492_4 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 451.0
HKD2_k127_2781492_5 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 368.0
HKD2_k127_2781492_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 368.0
HKD2_k127_2781492_7 PFAM Binding-protein-dependent transport K02025,K10228 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 322.0
HKD2_k127_2781492_8 alcohol dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 319.0
HKD2_k127_2781492_9 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 321.0
HKD2_k127_2782715_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 577.0
HKD2_k127_2782715_1 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 347.0
HKD2_k127_2782715_2 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 0.00000000009533 64.0
HKD2_k127_2790201_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 330.0
HKD2_k127_2790201_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000006577 105.0
HKD2_k127_2790201_2 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000002729 94.0
HKD2_k127_2790201_3 SCO1/SenC - - - 0.0000000000006601 74.0
HKD2_k127_2790201_4 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.0000001407 60.0
HKD2_k127_2799065_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 489.0
HKD2_k127_2799065_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 386.0
HKD2_k127_2799065_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 407.0
HKD2_k127_2799065_3 Peptidase family S51 - - - 0.000000000000000000000000000000000000000000000000000000000000000008971 243.0
HKD2_k127_2799065_4 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000002983 124.0
HKD2_k127_2799065_5 GTP binding - - - 0.0000000000000000002574 101.0
HKD2_k127_2851241_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 380.0
HKD2_k127_2851241_1 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 332.0
HKD2_k127_2851241_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 296.0
HKD2_k127_2851241_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000215 255.0
HKD2_k127_2851241_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000005819 172.0
HKD2_k127_2851246_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 649.0
HKD2_k127_2851246_1 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 350.0
HKD2_k127_2851246_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000000000000002511 171.0
HKD2_k127_2851246_3 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000002422 161.0
HKD2_k127_2851246_4 - - - - 0.000000000004047 76.0
HKD2_k127_2851246_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000009322 76.0
HKD2_k127_2851246_6 - - - - 0.0009976 49.0
HKD2_k127_2858483_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 608.0
HKD2_k127_2858483_1 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 503.0
HKD2_k127_2858483_2 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002163 230.0
HKD2_k127_2858483_3 Capsule synthesis protein, CapA K07282 - - 0.000000000000000000000000000000000000000000000000000000005329 219.0
HKD2_k127_2858483_4 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000008544 168.0
HKD2_k127_286975_0 DNA-binding transcription factor activity K03710 - - 0.00000000000000000000000000000001198 139.0
HKD2_k127_286975_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000006404 112.0
HKD2_k127_2884554_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 385.0
HKD2_k127_2884554_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004394 228.0
HKD2_k127_2884554_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000002522 202.0
HKD2_k127_2884554_3 phospholipase C K01114 - 3.1.4.3 0.000000000000000000000000000000000000000005426 173.0
HKD2_k127_2884554_4 ATP-NAD kinase - - - 0.000000000000000000001336 99.0
HKD2_k127_2884554_5 SnoaL-like domain - - - 0.000000000000000000264 94.0
HKD2_k127_2884554_6 Helix-turn-helix domain - - - 0.0000000002521 63.0
HKD2_k127_2884554_7 Helix-turn-helix domain - - - 0.0000007365 52.0
HKD2_k127_2884554_8 GYD domain - - - 0.0005155 46.0
HKD2_k127_2894947_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 527.0
HKD2_k127_2894947_1 PFAM glycosyl transferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 320.0
HKD2_k127_2894947_10 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000004349 190.0
HKD2_k127_2894947_11 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000007668 172.0
HKD2_k127_2894947_12 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000003474 169.0
HKD2_k127_2894947_13 polysaccharide biosynthetic process K01992 - - 0.00000000000000000000000000000000001855 154.0
HKD2_k127_2894947_14 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000001777 153.0
HKD2_k127_2894947_15 AI-2E family transporter - - - 0.0000000000000000000005692 111.0
HKD2_k127_2894947_16 Transglycosylase associated protein - - - 0.000000005228 69.0
HKD2_k127_2894947_17 Glycosyl transferases group 1 - - - 0.00000005218 65.0
HKD2_k127_2894947_18 - - - - 0.00002013 55.0
HKD2_k127_2894947_19 - - - - 0.0001503 53.0
HKD2_k127_2894947_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 292.0
HKD2_k127_2894947_3 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 282.0
HKD2_k127_2894947_4 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007585 281.0
HKD2_k127_2894947_5 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004745 260.0
HKD2_k127_2894947_6 Major intrinsic protein - - - 0.00000000000000000000000000000000000000000000000000000000001345 216.0
HKD2_k127_2894947_7 beta-galactosidase activity K01219,K21000 - 3.2.1.81 0.00000000000000000000000000000000000000000000000000000000003993 222.0
HKD2_k127_2894947_8 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000128 219.0
HKD2_k127_2894947_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000004017 190.0
HKD2_k127_2900369_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003229 275.0
HKD2_k127_2900369_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000001893 206.0
HKD2_k127_2913894_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002597 268.0
HKD2_k127_2913894_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000003426 175.0
HKD2_k127_2913894_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000262 131.0
HKD2_k127_2913894_3 Histidine biosynthesis protein K01814 - 5.3.1.16 0.000000000000000000000000137 124.0
HKD2_k127_2913894_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0004131 46.0
HKD2_k127_2931086_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 314.0
HKD2_k127_2931086_1 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000001602 57.0
HKD2_k127_2931086_2 Bacterial Ig-like domain (group 3) K20276 - - 0.00002018 57.0
HKD2_k127_2963914_0 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 547.0
HKD2_k127_2963914_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 445.0
HKD2_k127_2963914_2 Protein of unknown function (DUF1269) - - - 0.00000000000000000000000004281 113.0
HKD2_k127_2970017_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 457.0
HKD2_k127_2970017_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 403.0
HKD2_k127_2970017_2 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005473 288.0
HKD2_k127_2970017_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000003278 268.0
HKD2_k127_2998651_0 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000004671 233.0
HKD2_k127_2998651_1 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000003073 107.0
HKD2_k127_2998651_2 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.000000000000000003955 91.0
HKD2_k127_3007326_0 GMC oxidoreductase K00108 - 1.1.99.1 2.141e-298 923.0
HKD2_k127_3007326_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 458.0
HKD2_k127_3007326_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006748 282.0
HKD2_k127_3007326_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
HKD2_k127_3007326_4 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000011 150.0
HKD2_k127_3007326_5 - - - - 0.00000000000000000000000000007529 128.0
HKD2_k127_3007326_6 Domain of unknown function (DUF4395) - - - 0.00000001126 64.0
HKD2_k127_3016765_0 succinate dehydrogenase or fumarate reductase, flavoprotein subunitGram-negative mitochondrial subgroup K00239,K00244 - 1.3.5.1,1.3.5.4 6.916e-224 704.0
HKD2_k127_3016765_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 367.0
HKD2_k127_3016765_10 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000007697 222.0
HKD2_k127_3016765_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000001826 216.0
HKD2_k127_3016765_12 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000987 144.0
HKD2_k127_3016765_13 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000000000002505 141.0
HKD2_k127_3016765_14 Protein of unknown function (DUF1290) - - - 0.000000000000000000000000000008365 121.0
HKD2_k127_3016765_15 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0002692 53.0
HKD2_k127_3016765_16 Glyco_18 K06306 - - 0.0005195 52.0
HKD2_k127_3016765_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 344.0
HKD2_k127_3016765_3 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 338.0
HKD2_k127_3016765_4 Succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 331.0
HKD2_k127_3016765_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000594 276.0
HKD2_k127_3016765_6 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006846 289.0
HKD2_k127_3016765_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001804 286.0
HKD2_k127_3016765_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000005786 260.0
HKD2_k127_3016765_9 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000009384 230.0
HKD2_k127_3020050_0 PFAM CobB CobQ domain protein glutamine amidotransferase K07009 - - 0.000000000000000000000000000000000000000000000002071 193.0
HKD2_k127_3020050_1 Domain of unknown function (DUF1727) - - - 0.0000000000000000000000000000000004807 143.0
HKD2_k127_3036754_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 429.0
HKD2_k127_3036754_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 - - 0.000000000002087 76.0
HKD2_k127_3087241_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000005708 256.0
HKD2_k127_3087241_1 BioY family K03523 - - 0.00000000000000000000000000000000000000000265 164.0
HKD2_k127_3087241_2 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000001432 149.0
HKD2_k127_3087241_3 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000009157 104.0
HKD2_k127_3109966_0 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000001942 261.0
HKD2_k127_3109966_1 Capsule synthesis protein, CapA K07282 - - 0.000000000000000000000000000000000000000000000000000000000000003639 237.0
HKD2_k127_3133905_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 1.5e-323 1009.0
HKD2_k127_3133905_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 314.0
HKD2_k127_3133905_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000001128 140.0
HKD2_k127_3133905_4 PFAM Peptidase family M23 - - - 0.0000006042 60.0
HKD2_k127_3176156_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
HKD2_k127_3176156_1 ACT domain protein - - - 0.0000009537 55.0
HKD2_k127_3176156_2 Pfam:DUF385 - - - 0.000001662 57.0
HKD2_k127_3183091_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 505.0
HKD2_k127_3183091_1 domain protein K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000004519 224.0
HKD2_k127_3183091_2 Putative NAD(P)-binding K03499 - - 0.00000000000000000000000000000001526 138.0
HKD2_k127_3183091_3 Universal stress protein family - - - 0.000000000000000000001336 100.0
HKD2_k127_3199110_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 606.0
HKD2_k127_3199110_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 497.0
HKD2_k127_3199110_10 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000000000000002232 133.0
HKD2_k127_3199110_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000003677 127.0
HKD2_k127_3199110_12 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000001337 126.0
HKD2_k127_3199110_13 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000001293 118.0
HKD2_k127_3199110_14 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000003244 117.0
HKD2_k127_3199110_15 lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.00000000000000000000004712 115.0
HKD2_k127_3199110_16 Lipid A biosynthesis K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.0000000000000000000004747 111.0
HKD2_k127_3199110_17 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000001019 107.0
HKD2_k127_3199110_18 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000002344 98.0
HKD2_k127_3199110_19 DNA-binding transcription factor activity K03892 - - 0.00000000000008009 76.0
HKD2_k127_3199110_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 368.0
HKD2_k127_3199110_20 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000002267 78.0
HKD2_k127_3199110_21 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000002257 67.0
HKD2_k127_3199110_22 PFAM glycosyl transferase family 39 K00728 - 2.4.1.109 0.0001324 57.0
HKD2_k127_3199110_23 amine dehydrogenase activity - - - 0.000796 53.0
HKD2_k127_3199110_3 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 325.0
HKD2_k127_3199110_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000009097 231.0
HKD2_k127_3199110_5 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001517 230.0
HKD2_k127_3199110_6 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000001307 169.0
HKD2_k127_3199110_7 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000454 162.0
HKD2_k127_3199110_8 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000009215 150.0
HKD2_k127_3199110_9 PFAM VanW family protein - - - 0.0000000000000000000000000000007094 140.0
HKD2_k127_3204929_0 Iron-sulfur cluster-binding domain K06871 - - 1.086e-197 628.0
HKD2_k127_3204929_1 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 504.0
HKD2_k127_3204929_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000006517 78.0
HKD2_k127_3204929_3 - - - - 0.0003474 51.0
HKD2_k127_3244253_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 476.0
HKD2_k127_3244253_1 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 451.0
HKD2_k127_3244253_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 366.0
HKD2_k127_3244253_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000006545 262.0
HKD2_k127_3244253_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000776 253.0
HKD2_k127_3244253_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000002812 184.0
HKD2_k127_3244253_6 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000003905 137.0
HKD2_k127_3244253_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000002867 151.0
HKD2_k127_3244253_8 recombinase activity K07450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000001447 136.0
HKD2_k127_3246653_0 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 530.0
HKD2_k127_3246653_1 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 361.0
HKD2_k127_3246653_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 316.0
HKD2_k127_3246653_3 COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - - - 0.000000000000000000000000000000000000000000001212 188.0
HKD2_k127_3246653_4 cellulase activity - - - 0.00000000000000000000000000000007653 144.0
HKD2_k127_3264426_0 Sulfatase K01130 - 3.1.6.1 0.0 1411.0
HKD2_k127_3264426_1 AI-2E family transporter - - - 0.0000000000000000000000000002887 131.0
HKD2_k127_3264426_2 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000000001915 119.0
HKD2_k127_3264426_3 Short C-terminal domain - - - 0.0000000000000162 80.0
HKD2_k127_3264426_4 helix_turn_helix, Lux Regulon K03556 - - 0.000000000006455 67.0
HKD2_k127_3264426_5 zinc-ribbon family - - - 0.000001187 58.0
HKD2_k127_3295949_0 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 375.0
HKD2_k127_3295949_1 Sulfate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 301.0
HKD2_k127_3295949_2 - - - - 0.0000000000000000000000000000000000000001209 160.0
HKD2_k127_3483736_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 519.0
HKD2_k127_3483736_1 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 423.0
HKD2_k127_3483736_2 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 383.0
HKD2_k127_3483736_3 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000008112 171.0
HKD2_k127_3483736_4 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000113 115.0
HKD2_k127_3483736_5 Protein of unknown function (DUF1269) - - - 0.0000398 49.0
HKD2_k127_359596_0 Aromatic amino acid lyase K01745 - 4.3.1.3 4.287e-253 791.0
HKD2_k127_359596_1 META domain - - - 0.00000000000000000000000000000000008966 143.0
HKD2_k127_3833786_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 608.0
HKD2_k127_3833786_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 347.0
HKD2_k127_3833786_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001836 291.0
HKD2_k127_3833786_3 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000006958 261.0
HKD2_k127_3833786_4 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000001648 237.0
HKD2_k127_3833786_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000002003 223.0
HKD2_k127_3833786_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000005565 190.0
HKD2_k127_3833786_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000002002 70.0
HKD2_k127_3836345_0 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 446.0
HKD2_k127_3836345_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 409.0
HKD2_k127_3836345_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001417 301.0
HKD2_k127_3836345_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000002808 171.0
HKD2_k127_3836345_4 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000004502 156.0
HKD2_k127_3836345_5 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000008602 93.0
HKD2_k127_3836345_6 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000002934 82.0
HKD2_k127_3836345_7 - - - - 0.00003667 52.0
HKD2_k127_3836345_8 helix_turn_helix, Lux Regulon - - - 0.00008006 51.0
HKD2_k127_3839966_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 375.0
HKD2_k127_3839966_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000005774 187.0
HKD2_k127_3845291_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 7.804e-231 745.0
HKD2_k127_3845291_1 GTP-binding protein TypA K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 531.0
HKD2_k127_3845291_2 cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 379.0
HKD2_k127_3845291_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 380.0
HKD2_k127_3845291_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 321.0
HKD2_k127_3845291_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000005718 136.0
HKD2_k127_3845291_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000006787 98.0
HKD2_k127_3845291_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000001541 81.0
HKD2_k127_3845291_8 Baseplate J-like protein K01218 - 3.2.1.78 0.000000001623 71.0
HKD2_k127_3847538_0 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 4.402e-233 728.0
HKD2_k127_3847538_1 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
HKD2_k127_3847538_2 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008936 284.0
HKD2_k127_3847538_3 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000001517 181.0
HKD2_k127_3847538_4 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000001923 176.0
HKD2_k127_3847538_5 TAP-like protein - - - 0.000000000000000004003 87.0
HKD2_k127_3848242_0 Succinyl-CoA ligase like flavodoxin domain K09181 - - 1.805e-270 844.0
HKD2_k127_3849239_0 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 425.0
HKD2_k127_3849239_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 331.0
HKD2_k127_3849239_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 296.0
HKD2_k127_3849239_3 PFAM Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000005192 168.0
HKD2_k127_3849239_4 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000007761 144.0
HKD2_k127_3849956_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 1.446e-205 680.0
HKD2_k127_3849956_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 578.0
HKD2_k127_3849956_10 Double zinc ribbon - - - 0.00000000000000000000002016 112.0
HKD2_k127_3849956_11 nUDIX hydrolase K01515,K08310 - 3.6.1.13,3.6.1.67 0.00000000000000001002 98.0
HKD2_k127_3849956_12 Two component regulator propeller - - - 0.0000000348 67.0
HKD2_k127_3849956_2 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 496.0
HKD2_k127_3849956_3 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 403.0
HKD2_k127_3849956_4 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000715 272.0
HKD2_k127_3849956_5 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000343 201.0
HKD2_k127_3849956_6 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000001954 157.0
HKD2_k127_3849956_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000008356 133.0
HKD2_k127_3849956_8 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000003558 123.0
HKD2_k127_3849956_9 ECF sigma factor K03088 - - 0.0000000000000000000000002164 114.0
HKD2_k127_3856311_0 lactoylglutathione lyase activity - - - 0.000000000000000000000002261 108.0
HKD2_k127_3861043_0 all-trans-retinol 13,14-reductase activity - - - 0.0000000000000000000000000000000000000000000001453 172.0
HKD2_k127_3861043_1 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000206 171.0
HKD2_k127_3861043_2 - - - - 0.0000000000000000000000000000047 123.0
HKD2_k127_3861043_3 Transcriptional regulator, MarR family - - - 0.00000000000000000000001436 115.0
HKD2_k127_3861043_4 - - - - 0.0002345 49.0
HKD2_k127_3861851_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 357.0
HKD2_k127_3861851_1 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 295.0
HKD2_k127_3861851_10 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000001422 108.0
HKD2_k127_3861851_11 - K03649 - 3.2.2.28 0.0000000000002298 79.0
HKD2_k127_3861851_2 PFAM photosystem I assembly BtpA K06971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001962 274.0
HKD2_k127_3861851_3 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 244.0
HKD2_k127_3861851_4 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000004087 218.0
HKD2_k127_3861851_5 amino acid - - - 0.0000000000000000000000000000000000000000000000000000002682 218.0
HKD2_k127_3861851_6 - - - - 0.0000000000000000000000000000000000000000000000001904 190.0
HKD2_k127_3861851_7 DeoR C terminal sensor domain K02081,K03436 - - 0.000000000000000000000000000000000000009425 155.0
HKD2_k127_3861851_8 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000008688 129.0
HKD2_k127_3861851_9 amino acid - - - 0.000000000000000000000000002306 128.0
HKD2_k127_3866434_0 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000003416 209.0
HKD2_k127_3866434_1 R3H domain - - - 0.0000000000000000000000000000000000000271 156.0
HKD2_k127_3866434_2 glyoxalase - - - 0.000000000000000000000001573 111.0
HKD2_k127_3869297_0 - - - - 0.00000000000000000000000000000000009205 151.0
HKD2_k127_3869297_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000001885 148.0
HKD2_k127_3869297_2 AI-2E family transporter - - - 0.000000007512 61.0
HKD2_k127_3887466_0 DNA primase, small subunit K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
HKD2_k127_3887466_1 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000003296 165.0
HKD2_k127_3887466_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000004386 161.0
HKD2_k127_3887466_3 Transcriptional regulatory protein, C terminal - - - 0.00002074 52.0
HKD2_k127_3895222_0 Pyridoxal-phosphate dependent enzyme - - - 3.202e-210 665.0
HKD2_k127_3895222_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.63e-197 638.0
HKD2_k127_3895222_2 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000003641 240.0
HKD2_k127_3901182_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 406.0
HKD2_k127_3901182_1 - - - - 0.000000000000000000000000000000000000000000005916 166.0
HKD2_k127_3902221_0 Cytochrome b/b6/petB K03891 - - 0.00000000000000000000000000000000000000000000000000000000001335 207.0
HKD2_k127_3902221_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000001498 162.0
HKD2_k127_3902221_2 Rieske 2Fe-2S - - - 0.000000000000000000000000009988 119.0
HKD2_k127_3902221_3 conserved protein (DUF2203) - - - 0.0000000000000001027 87.0
HKD2_k127_3902221_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000001318 83.0
HKD2_k127_3902221_5 - - - - 0.00001096 58.0
HKD2_k127_3902221_6 Domain of unknown function (DUF309) K09763 - - 0.0000235 53.0
HKD2_k127_3902221_7 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.0005305 52.0
HKD2_k127_3906176_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 360.0
HKD2_k127_3906176_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000004744 159.0
HKD2_k127_3906176_2 glycosyl transferase, family 39 - - - 0.00000000000000000001258 108.0
HKD2_k127_3906176_3 Glycosyltransferase family 87 - - - 0.0000003744 57.0
HKD2_k127_39306_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 427.0
HKD2_k127_39306_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000004366 177.0
HKD2_k127_39306_2 Belongs to the UPF0235 family K09131 - - 0.0000001183 62.0
HKD2_k127_3932449_0 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism General function prediction only - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 298.0
HKD2_k127_3932449_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000001895 179.0
HKD2_k127_3932449_2 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000001009 87.0
HKD2_k127_3933211_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.098e-252 791.0
HKD2_k127_3933211_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.437e-230 763.0
HKD2_k127_3933211_10 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 289.0
HKD2_k127_3933211_11 PFAM Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001267 286.0
HKD2_k127_3933211_12 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005124 258.0
HKD2_k127_3933211_13 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000268 268.0
HKD2_k127_3933211_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000009453 250.0
HKD2_k127_3933211_15 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000003692 234.0
HKD2_k127_3933211_16 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000003129 201.0
HKD2_k127_3933211_17 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000003161 193.0
HKD2_k127_3933211_18 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000000000001643 167.0
HKD2_k127_3933211_19 F420-dependent oxidoreductase, Rv1855c family - - - 0.00000000000000000000000000000000004736 156.0
HKD2_k127_3933211_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.417e-230 733.0
HKD2_k127_3933211_20 AdoMet dependent proline di-methyltransferase - - - 0.00000000000000000000000000000000049 142.0
HKD2_k127_3933211_21 4Fe-4S binding domain - - - 0.0000000000000000000000000001181 120.0
HKD2_k127_3933211_22 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000003619 125.0
HKD2_k127_3933211_23 GAF domain - - - 0.00000000000000000000008789 114.0
HKD2_k127_3933211_24 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000198 115.0
HKD2_k127_3933211_25 PFAM CBS domain containing protein - - - 0.000000000000000001062 94.0
HKD2_k127_3933211_26 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000002185 92.0
HKD2_k127_3933211_27 Family of unknown function (DUF5317) - - - 0.000000000001136 76.0
HKD2_k127_3933211_28 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000001636 79.0
HKD2_k127_3933211_29 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000152 61.0
HKD2_k127_3933211_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.228e-203 639.0
HKD2_k127_3933211_30 Copper binding proteins, plastocyanin/azurin family - - - 0.0000001843 61.0
HKD2_k127_3933211_4 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 529.0
HKD2_k127_3933211_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 481.0
HKD2_k127_3933211_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 454.0
HKD2_k127_3933211_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 397.0
HKD2_k127_3933211_8 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 355.0
HKD2_k127_3933211_9 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 355.0
HKD2_k127_3933455_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 511.0
HKD2_k127_3933455_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000003748 132.0
HKD2_k127_3933455_2 ATP synthase F(0) sector subunit b K02109 - - 0.0000000000000005639 85.0
HKD2_k127_3933455_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000006614 59.0
HKD2_k127_3934746_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 5.188e-221 716.0
HKD2_k127_3934746_1 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 565.0
HKD2_k127_3934746_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 485.0
HKD2_k127_3934746_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 373.0
HKD2_k127_3934746_4 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000000000000000001082 108.0
HKD2_k127_3934746_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000002899 102.0
HKD2_k127_3934746_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000002581 97.0
HKD2_k127_3934746_7 NADH ubiquinone oxidoreductase K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0001857 44.0
HKD2_k127_3939338_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 581.0
HKD2_k127_3939338_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 488.0
HKD2_k127_3939338_10 Probable zinc-ribbon domain - - - 0.000000000000000000000000002339 120.0
HKD2_k127_3939338_11 AAA domain - - - 0.000000000000000000000001127 121.0
HKD2_k127_3939338_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 312.0
HKD2_k127_3939338_3 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000003875 238.0
HKD2_k127_3939338_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000516 220.0
HKD2_k127_3939338_5 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000003824 164.0
HKD2_k127_3939338_6 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000123 168.0
HKD2_k127_3939338_7 PFAM Metallophosphoesterase K01090 - 3.1.3.16 0.000000000000000000000000000000000000001352 165.0
HKD2_k127_3939338_8 Peptidase family S51 - - - 0.0000000000000000000000000000000004242 140.0
HKD2_k127_3939338_9 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000002189 142.0
HKD2_k127_3980371_0 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
HKD2_k127_4006833_0 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000003179 231.0
HKD2_k127_4006833_1 PFAM ATP-binding region, ATPase domain protein - - - 0.00000001459 68.0
HKD2_k127_4011419_0 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 279.0
HKD2_k127_4011419_1 transmembrane transport K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000004487 229.0
HKD2_k127_4011419_2 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000001541 138.0
HKD2_k127_4011419_3 Peptidase MA superfamily - - - 0.0000000000000000000000008456 122.0
HKD2_k127_4011419_4 cysteine-tRNA ligase activity - - - 0.000003145 59.0
HKD2_k127_4011419_5 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.000119 54.0
HKD2_k127_4031239_0 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
HKD2_k127_4031239_1 PFAM glycoside hydrolase family 25 - - - 0.00000000000000000000000000000000000003659 164.0
HKD2_k127_4039546_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.826e-195 635.0
HKD2_k127_4039546_1 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 594.0
HKD2_k127_4039546_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000003488 96.0
HKD2_k127_4039546_11 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000002676 57.0
HKD2_k127_4039546_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 518.0
HKD2_k127_4039546_3 Aminotransferase K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
HKD2_k127_4039546_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 458.0
HKD2_k127_4039546_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002334 276.0
HKD2_k127_4039546_6 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
HKD2_k127_4039546_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004379 262.0
HKD2_k127_4039546_8 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000007798 195.0
HKD2_k127_4039546_9 CoA binding domain K01740,K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.49 0.000000000000000000000000000000000000659 146.0
HKD2_k127_4054564_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 2.516e-196 645.0
HKD2_k127_4054564_1 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 399.0
HKD2_k127_4054564_2 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000000000000000000000000000156 170.0
HKD2_k127_4054564_3 heat shock protein binding - - - 0.00000006231 66.0
HKD2_k127_4096618_0 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009007 250.0
HKD2_k127_4096618_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004026 247.0
HKD2_k127_4096618_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.00000000000000000000000006967 109.0
HKD2_k127_4096618_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - - 0.000000000000000000000003004 108.0
HKD2_k127_4096618_4 4Fe-4S single cluster domain - - - 0.00000000000000000001623 99.0
HKD2_k127_4111991_0 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 530.0
HKD2_k127_4111991_1 pfam abc K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002194 287.0
HKD2_k127_4111991_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000008051 232.0
HKD2_k127_4111991_3 Belongs to the bacterial solute-binding protein 3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000009539 226.0
HKD2_k127_4111991_4 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029 - - 0.0000000000000000000000000000000000000000000000000000000004376 213.0
HKD2_k127_4111991_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000003981 216.0
HKD2_k127_4111991_6 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000007067 155.0
HKD2_k127_4111991_7 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000003365 137.0
HKD2_k127_4111991_8 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000005692 105.0
HKD2_k127_4118607_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000001705 234.0
HKD2_k127_4118607_1 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000005976 158.0
HKD2_k127_4118607_2 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000002862 148.0
HKD2_k127_4118607_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000001227 126.0
HKD2_k127_4118607_4 PFAM Peptidase M22, glycoprotease K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000004167 81.0
HKD2_k127_4118607_5 - - - - 0.00002937 50.0
HKD2_k127_4118607_6 MutL protein - - - 0.0008036 52.0
HKD2_k127_4120220_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 479.0
HKD2_k127_4120220_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009892 452.0
HKD2_k127_4120220_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000002243 205.0
HKD2_k127_412323_0 peptidase S9 prolyl oligopeptidase active site domain protein - - - 5.002e-216 708.0
HKD2_k127_412323_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 550.0
HKD2_k127_412323_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 488.0
HKD2_k127_412323_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000003269 233.0
HKD2_k127_412323_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000001629 249.0
HKD2_k127_412323_5 acetyltransferase - - - 0.000000000000000000001161 111.0
HKD2_k127_412323_6 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.0000000002762 61.0
HKD2_k127_4129468_0 Aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 516.0
HKD2_k127_4129468_1 PFAM TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 386.0
HKD2_k127_4129468_2 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000197 153.0
HKD2_k127_4129468_3 PFAM NUDIX domain - - - 0.00000000000000000000000000000000001915 151.0
HKD2_k127_4129468_4 ECF sigma factor K03088 - - 0.0000000000000000000001363 105.0
HKD2_k127_4129468_5 antibiotic catabolic process K13277 - - 0.0000000000000004796 90.0
HKD2_k127_4129468_6 amine dehydrogenase activity - - - 0.00000000001709 77.0
HKD2_k127_4129468_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0008741 42.0
HKD2_k127_4187055_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.038e-235 776.0
HKD2_k127_4187055_1 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 5.603e-202 656.0
HKD2_k127_4187055_10 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001816 270.0
HKD2_k127_4187055_11 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000001375 221.0
HKD2_k127_4187055_12 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000003691 207.0
HKD2_k127_4187055_13 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000004624 180.0
HKD2_k127_4187055_14 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000009422 172.0
HKD2_k127_4187055_15 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000006975 152.0
HKD2_k127_4187055_16 tryptophan synthase activity K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000222 130.0
HKD2_k127_4187055_17 NUDIX hydrolase - - - 0.00000000000000000000000000000005158 136.0
HKD2_k127_4187055_18 FemAB family K05363,K11693 - 2.3.2.10,2.3.2.16 0.00000000000000000008422 103.0
HKD2_k127_4187055_19 Bacterial Ig-like domain - - - 0.000000000005569 79.0
HKD2_k127_4187055_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 623.0
HKD2_k127_4187055_20 - - - - 0.0001036 50.0
HKD2_k127_4187055_21 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0006868 52.0
HKD2_k127_4187055_22 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.0007138 50.0
HKD2_k127_4187055_3 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 421.0
HKD2_k127_4187055_4 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 417.0
HKD2_k127_4187055_5 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 366.0
HKD2_k127_4187055_6 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 319.0
HKD2_k127_4187055_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 289.0
HKD2_k127_4187055_8 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003918 266.0
HKD2_k127_4187055_9 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001694 263.0
HKD2_k127_4191171_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001622 262.0
HKD2_k127_4191171_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000006856 196.0
HKD2_k127_4222782_0 L-carnitine dehydratase bile acid-inducible protein F K07749,K08298 - 2.8.3.16,2.8.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 459.0
HKD2_k127_4222782_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001641 257.0
HKD2_k127_4222782_2 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000004403 100.0
HKD2_k127_4222782_3 Domain of unknown function (DUF1287) K09974 - - 0.000000000008764 70.0
HKD2_k127_4281334_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 576.0
HKD2_k127_4281334_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 414.0
HKD2_k127_4281334_10 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000007257 68.0
HKD2_k127_4281334_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 360.0
HKD2_k127_4281334_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 301.0
HKD2_k127_4281334_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000004471 272.0
HKD2_k127_4281334_5 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000001929 249.0
HKD2_k127_4281334_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000002898 177.0
HKD2_k127_4281334_7 PFAM extracellular solute-binding protein family 1 K11069 - - 0.00000000000000000000000000145 120.0
HKD2_k127_4281334_8 MOSC domain - - - 0.000000000000003004 89.0
HKD2_k127_4281334_9 - - - - 0.00000000003036 71.0
HKD2_k127_4300640_0 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 415.0
HKD2_k127_4300640_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000003921 235.0
HKD2_k127_4300640_2 - - - - 0.000000000000000000000000000000000000000000000000007435 186.0
HKD2_k127_4337879_0 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 413.0
HKD2_k127_4337879_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000001184 123.0
HKD2_k127_4359968_0 tRNA synthetases class I (C) catalytic domain K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 413.0
HKD2_k127_4359968_1 Sulfate permease K03321 - - 0.00000007443 57.0
HKD2_k127_4359968_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000003822 57.0
HKD2_k127_436128_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 310.0
HKD2_k127_436128_1 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000004203 252.0
HKD2_k127_436128_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000003275 105.0
HKD2_k127_4365352_0 - - - - 0.000000000000000000000000000000000000000002414 166.0
HKD2_k127_4365352_1 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000004807 177.0
HKD2_k127_4365352_2 - - - - 0.0000000000001052 81.0
HKD2_k127_436930_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 359.0
HKD2_k127_436930_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000003138 235.0
HKD2_k127_436930_2 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000148 159.0
HKD2_k127_436930_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000001767 153.0
HKD2_k127_436930_4 PFAM binding-protein-dependent transport systems inner membrane component K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000007639 127.0
HKD2_k127_436930_5 transcriptional regulator K03892 - - 0.0000000000000000000000584 102.0
HKD2_k127_436930_6 Phosphoglycerate mutase family K08296 - - 0.0000000000000000003373 98.0
HKD2_k127_4370889_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 6.404e-267 844.0
HKD2_k127_4370889_1 Choline/ethanolamine kinase - - - 0.0000000000000002153 81.0
HKD2_k127_4372560_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 2.248e-241 757.0
HKD2_k127_4372560_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 3.909e-219 696.0
HKD2_k127_4372560_10 Transcriptional regulator - - - 0.0001502 51.0
HKD2_k127_4372560_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 545.0
HKD2_k127_4372560_3 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 422.0
HKD2_k127_4372560_4 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 319.0
HKD2_k127_4372560_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005382 286.0
HKD2_k127_4372560_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000004853 121.0
HKD2_k127_4372560_7 Glycosyl transferases group 1 - - - 0.0000000000000000000001652 109.0
HKD2_k127_4372560_8 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000004198 87.0
HKD2_k127_4372560_9 Cold shock K03704 - - 0.0000000003617 65.0
HKD2_k127_4393385_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000002469 194.0
HKD2_k127_4393385_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05568 - 1.6.5.3 0.0000000000002643 83.0
HKD2_k127_4406696_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1219.0
HKD2_k127_4406696_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 309.0
HKD2_k127_4406696_10 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000000000000000002986 151.0
HKD2_k127_4406696_11 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000883 148.0
HKD2_k127_4406696_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K07003 - - 0.000000000000000000000000001536 123.0
HKD2_k127_4406696_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 302.0
HKD2_k127_4406696_3 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001505 283.0
HKD2_k127_4406696_4 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003901 276.0
HKD2_k127_4406696_5 YHS domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001452 272.0
HKD2_k127_4406696_6 COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
HKD2_k127_4406696_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000004237 248.0
HKD2_k127_4406696_8 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000001742 171.0
HKD2_k127_4406696_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000564 165.0
HKD2_k127_4408617_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 563.0
HKD2_k127_4408617_1 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000000003723 91.0
HKD2_k127_4408617_2 Belongs to the 5'-nucleotidase family K01081,K06931,K08693 - 3.1.3.5,3.1.3.6,3.1.4.16 0.0008685 53.0
HKD2_k127_4410552_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 6.381e-295 936.0
HKD2_k127_4410552_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 468.0
HKD2_k127_4410552_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 416.0
HKD2_k127_4410552_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 364.0
HKD2_k127_4410552_4 DUF218 domain - - - 0.000000000000000000000000000000000000000002871 170.0
HKD2_k127_442111_0 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 427.0
HKD2_k127_442111_1 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 385.0
HKD2_k127_442111_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 346.0
HKD2_k127_442111_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 318.0
HKD2_k127_442111_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006258 309.0
HKD2_k127_442111_5 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000283 296.0
HKD2_k127_442111_6 DRTGG domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001093 254.0
HKD2_k127_442111_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000202 213.0
HKD2_k127_442111_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000008118 193.0
HKD2_k127_442111_9 - - - - 0.0000009415 57.0
HKD2_k127_4425167_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 378.0
HKD2_k127_4426448_0 FAD dependent oxidoreductase - - - 0.000007021 57.0
HKD2_k127_4426448_1 Flagellar Assembly Protein A K09749 - - 0.00007583 54.0
HKD2_k127_4430856_0 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 556.0
HKD2_k127_4430856_1 PFAM aminotransferase, class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 397.0
HKD2_k127_4430856_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 310.0
HKD2_k127_4430856_3 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000006714 211.0
HKD2_k127_4430856_4 Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000004802 203.0
HKD2_k127_4430856_5 SPTR D1CGX5 Response regulator receiver protein - - - 0.00000000000000009862 89.0
HKD2_k127_4444849_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 503.0
HKD2_k127_4444849_1 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 423.0
HKD2_k127_4444849_2 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 390.0
HKD2_k127_4444849_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000007526 231.0
HKD2_k127_4444849_4 cysteine-tRNA ligase activity - - - 0.000000000000000000000000000000000000000000000000000001372 209.0
HKD2_k127_4444849_5 VIT family - - - 0.000000000000000000000000000000000000000000000000049 192.0
HKD2_k127_4444849_6 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000001549 151.0
HKD2_k127_4444849_7 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000000000000000000005857 104.0
HKD2_k127_4455055_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 614.0
HKD2_k127_4455055_1 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 563.0
HKD2_k127_4455055_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 355.0
HKD2_k127_4455055_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000005974 200.0
HKD2_k127_4455055_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000002158 138.0
HKD2_k127_4455055_5 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000006743 89.0
HKD2_k127_4455055_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000001552 59.0
HKD2_k127_4455055_7 Colicin V production protein K03558 - - 0.000001243 58.0
HKD2_k127_448637_0 ABC transporter K06147 - - 5.581e-238 758.0
HKD2_k127_448637_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 413.0
HKD2_k127_448637_10 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00001567 57.0
HKD2_k127_448637_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 344.0
HKD2_k127_448637_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 313.0
HKD2_k127_448637_4 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000001422 263.0
HKD2_k127_448637_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000002356 256.0
HKD2_k127_448637_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000002987 169.0
HKD2_k127_448637_7 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000004451 128.0
HKD2_k127_448637_8 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000001268 106.0
HKD2_k127_448637_9 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000002549 94.0
HKD2_k127_4511381_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 326.0
HKD2_k127_4511381_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 310.0
HKD2_k127_4511381_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000007073 257.0
HKD2_k127_4511381_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000277 229.0
HKD2_k127_4511381_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000003963 232.0
HKD2_k127_4511381_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000001152 212.0
HKD2_k127_4511381_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000001838 64.0
HKD2_k127_4511381_7 Belongs to the UPF0102 family K07460 - - 0.000001024 59.0
HKD2_k127_462199_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.345e-223 715.0
HKD2_k127_462199_1 PFAM Bacterial regulatory proteins, luxR family K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 399.0
HKD2_k127_462199_2 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000001269 201.0
HKD2_k127_462199_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000001288 134.0
HKD2_k127_462199_4 sequence-specific DNA binding K01356,K22299 - 3.4.21.88 0.0000000000000007402 81.0
HKD2_k127_4652065_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003948 287.0
HKD2_k127_4652065_1 ABC-2 family transporter protein K01992 - - 0.0001189 52.0
HKD2_k127_4663376_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 578.0
HKD2_k127_4663376_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 487.0
HKD2_k127_4663376_2 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 453.0
HKD2_k127_4663376_3 Uridine phosphorylase K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000000001474 236.0
HKD2_k127_4663376_4 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000004364 197.0
HKD2_k127_4663376_5 - - - - 0.0000000000001549 70.0
HKD2_k127_4663376_6 Binds directly to 16S ribosomal RNA K02968 - - 0.0000001418 61.0
HKD2_k127_4715837_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 317.0
HKD2_k127_4715837_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000004958 224.0
HKD2_k127_4715837_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000009754 142.0
HKD2_k127_4763655_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002841 264.0
HKD2_k127_4763655_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000001766 209.0
HKD2_k127_4763655_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001799 199.0
HKD2_k127_4763655_3 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.0000000000000000000000000000000000001348 153.0
HKD2_k127_4763655_4 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000001638 131.0
HKD2_k127_4763655_5 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.000000000000000000000000000001903 129.0
HKD2_k127_4773068_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1039.0
HKD2_k127_4773068_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 558.0
HKD2_k127_4773068_2 Large extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 596.0
HKD2_k127_4773068_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000002668 224.0
HKD2_k127_4773068_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000007724 155.0
HKD2_k127_4773068_6 - - - - 0.00002514 51.0
HKD2_k127_487208_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000384 246.0
HKD2_k127_487208_1 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000002498 207.0
HKD2_k127_487208_2 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.0000000000000000000000000000000000000000000006281 177.0
HKD2_k127_487208_3 Spermidine putrescine ABC transporter substrate-binding protein K11069 - - 0.0000000000000002121 92.0
HKD2_k127_489017_0 Phage integrase family K04763 GO:0008150,GO:0040007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004791 265.0
HKD2_k127_489017_1 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000001696 195.0
HKD2_k127_489017_2 Peptidase M50 - - - 0.00000000000000000000000000000000000000002429 160.0
HKD2_k127_489017_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000003777 153.0
HKD2_k127_489017_4 PFAM membrane-flanked domain - - - 0.000000000000000000000000000009966 136.0
HKD2_k127_489017_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000004032 106.0
HKD2_k127_489017_6 mRNA catabolic process - - - 0.000000006295 68.0
HKD2_k127_4940544_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 473.0
HKD2_k127_4940544_1 PFAM BMC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 295.0
HKD2_k127_4940544_2 BMC K04027 - - 0.00000000000000000000000000000000001786 141.0
HKD2_k127_4940544_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000006604 121.0
HKD2_k127_4940544_4 propanediol utilization protein - - - 0.00000000000000000000000008279 120.0
HKD2_k127_4940544_5 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000001095 96.0
HKD2_k127_4940544_6 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000008147 81.0
HKD2_k127_4940544_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000005015 76.0
HKD2_k127_4940544_8 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000007072 76.0
HKD2_k127_50709_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.209e-264 824.0
HKD2_k127_5112879_0 Membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 317.0
HKD2_k127_5112879_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 273.0
HKD2_k127_5112879_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000004003 188.0
HKD2_k127_5112879_3 - - - - 0.0000000000000000000000000002391 122.0
HKD2_k127_5112879_4 PucR C-terminal helix-turn-helix domain - - - 0.00000000000000005474 96.0
HKD2_k127_5112879_5 Belongs to the glycosyl hydrolase 57 family - - - 0.00000004144 59.0
HKD2_k127_5113764_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 425.0
HKD2_k127_5113764_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000001929 244.0
HKD2_k127_5113764_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000002407 218.0
HKD2_k127_5113764_3 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000005354 168.0
HKD2_k127_5113764_4 Transcriptional regulator K05346 - - 0.0000000000000000000000000000000000005843 148.0
HKD2_k127_5113764_5 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000003188 111.0
HKD2_k127_5113764_6 Protein of unknown function (DUF971) - - - 0.00000000000005211 74.0
HKD2_k127_5126881_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
HKD2_k127_5126881_1 YHYH protein - - - 0.0000000000003312 75.0
HKD2_k127_5126881_2 - - - - 0.00000004122 63.0
HKD2_k127_5137246_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 483.0
HKD2_k127_5142800_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 488.0
HKD2_k127_5142800_1 aldo keto reductase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 317.0
HKD2_k127_5142800_2 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004294 232.0
HKD2_k127_5142800_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000001282 97.0
HKD2_k127_5142800_4 ACT domain protein - - - 0.0000000000003926 77.0
HKD2_k127_5148784_0 ATP dependent DNA ligase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 544.0
HKD2_k127_5148784_1 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000000000001148 141.0
HKD2_k127_5148786_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009058,GO:0009059,GO:0009249,GO:0009898,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0034645,GO:0036211,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.199 0.0000000000000000000000000000000000000000000001352 182.0
HKD2_k127_5148786_1 Acyltransferase K00655 - 2.3.1.51 0.000000000001892 78.0
HKD2_k127_5149945_0 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 552.0
HKD2_k127_5149945_1 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 429.0
HKD2_k127_5149945_10 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000003342 117.0
HKD2_k127_5149945_2 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 410.0
HKD2_k127_5149945_3 Binding-protein-dependent transport systems inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 338.0
HKD2_k127_5149945_4 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000424 249.0
HKD2_k127_5149945_5 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005763 257.0
HKD2_k127_5149945_6 nitrite reductase [NAD(P)H] activity K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000002908 197.0
HKD2_k127_5149945_7 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000000007167 199.0
HKD2_k127_5149945_8 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000001417 170.0
HKD2_k127_5149945_9 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000002166 153.0
HKD2_k127_5151374_0 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 465.0
HKD2_k127_5151374_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000008745 138.0
HKD2_k127_5151374_2 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000009083 64.0
HKD2_k127_5178817_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 631.0
HKD2_k127_5178817_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 421.0
HKD2_k127_5178817_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 409.0
HKD2_k127_5178817_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000008937 163.0
HKD2_k127_5178817_4 NUDIX domain - - - 0.000000000000000000000000000000004028 134.0
HKD2_k127_5185117_0 trimethylamine methyltransferase K14083 - 2.1.1.250 2.153e-201 635.0
HKD2_k127_5185117_1 Cold shock protein K03704 - - 0.0000000007464 67.0
HKD2_k127_5185117_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.0005464 46.0
HKD2_k127_5187113_0 Aldo/keto reductase family K00064 - 1.1.1.122 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 348.0
HKD2_k127_5187113_1 PFAM pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 308.0
HKD2_k127_5187113_2 FR47-like protein - - - 0.000000003929 57.0
HKD2_k127_5190364_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 391.0
HKD2_k127_5190364_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 328.0
HKD2_k127_5190364_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 302.0
HKD2_k127_5190364_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001902 275.0
HKD2_k127_5190364_4 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000005256 179.0
HKD2_k127_5190364_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000192 75.0
HKD2_k127_5191576_0 PFAM RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 378.0
HKD2_k127_5191576_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 297.0
HKD2_k127_5191576_2 - K06862 - - 0.000000000000000000000000000000000000000000000000000000001732 207.0
HKD2_k127_5191576_3 Catalyzes the reversible retro-aldol cleavage of both 5- keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde K01630 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008672,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046392,GO:0046395,GO:0071704,GO:1901575 4.1.2.20 0.000000000000000000000000000000000000000000000002313 183.0
HKD2_k127_5191576_4 esterase - - - 0.00000000000000000000001322 113.0
HKD2_k127_5191576_5 Pyridoxamine 5'-phosphate oxidase - - - 0.0003041 53.0
HKD2_k127_5203576_0 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 523.0
HKD2_k127_5203576_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000002636 243.0
HKD2_k127_5203576_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000885 229.0
HKD2_k127_5203576_3 - - - - 0.000000005525 69.0
HKD2_k127_5204332_0 cytochrome complex assembly - - - 0.00000000000000000000000000000000000009944 156.0
HKD2_k127_5204332_1 Protein of unknown function with PCYCGC motif - - - 0.00000000000003998 81.0
HKD2_k127_5204332_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000005439 53.0
HKD2_k127_5240629_0 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007417 273.0
HKD2_k127_5240629_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000002291 243.0
HKD2_k127_5240629_2 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000003269 191.0
HKD2_k127_5240629_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000008012 145.0
HKD2_k127_5240629_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000008646 86.0
HKD2_k127_5252924_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 522.0
HKD2_k127_5252924_1 Flavin containing amine oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 364.0
HKD2_k127_5252924_10 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000001898 168.0
HKD2_k127_5252924_11 DegV family - - - 0.0000000000000000000000000000000000002208 156.0
HKD2_k127_5252924_12 - - - - 0.0000000000000000000000000000000001199 143.0
HKD2_k127_5252924_13 toxin-antitoxin pair type II binding - - - 0.000000000000000000000002801 104.0
HKD2_k127_5252924_14 Polyketide cyclase - - - 0.00000000000000000003213 98.0
HKD2_k127_5252924_16 - - - - 0.0000000002707 67.0
HKD2_k127_5252924_17 - - - - 0.00000003441 62.0
HKD2_k127_5252924_2 Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 335.0
HKD2_k127_5252924_3 phage tail protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
HKD2_k127_5252924_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001306 259.0
HKD2_k127_5252924_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001131 234.0
HKD2_k127_5252924_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000001808 228.0
HKD2_k127_5252924_7 Voltage gated chloride channel - - - 0.00000000000000000000000000000000000000000000000000000006472 219.0
HKD2_k127_5252924_8 PIN domain - - - 0.00000000000000000000000000000000000000002083 160.0
HKD2_k127_5252924_9 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000004726 173.0
HKD2_k127_5283398_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 338.0
HKD2_k127_5283398_1 response regulator K07668,K07775 - - 0.0000000000000000000000000000000000000000000000000000000000000000004851 237.0
HKD2_k127_5283398_2 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000001741 204.0
HKD2_k127_5283398_3 Histidine kinase-like ATPases K07642 - 2.7.13.3 0.000000000000000000000000000000002017 149.0
HKD2_k127_5283398_6 pyridoxamine 5-phosphate - - - 0.000000000002051 76.0
HKD2_k127_5304226_0 radical SAM K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 608.0
HKD2_k127_5304226_1 Sulfate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 382.0
HKD2_k127_5304226_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00001723 55.0
HKD2_k127_5329739_0 FeS assembly protein SufB K09014 - - 1.601e-222 698.0
HKD2_k127_5329739_1 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 355.0
HKD2_k127_5329739_2 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000007878 207.0
HKD2_k127_5329739_3 Benzene 1,2-dioxygenase K05710 - - 0.0000000000000001488 87.0
HKD2_k127_5329739_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000001614 75.0
HKD2_k127_5337126_0 L-glyceraldehyde 3-phosphate reductase K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 559.0
HKD2_k127_5337126_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 479.0
HKD2_k127_5337126_10 ABC transporter K01990 - - 0.000000000000000000000000000000004603 136.0
HKD2_k127_5337126_11 YCII-related domain - - - 0.00000000000000000000288 97.0
HKD2_k127_5337126_2 Family 4 glycosyl hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 466.0
HKD2_k127_5337126_3 ABC transporter (Permease) K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 346.0
HKD2_k127_5337126_4 Sugar ABC transporter substrate-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 328.0
HKD2_k127_5337126_5 Binding-protein-dependent transport system inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 310.0
HKD2_k127_5337126_6 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 328.0
HKD2_k127_5337126_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000001547 201.0
HKD2_k127_5337126_8 Carbohydrate kinase - - - 0.000000000000000000000000000000000000002427 163.0
HKD2_k127_5337126_9 UTRA K03710 - - 0.00000000000000000000000000000000134 140.0
HKD2_k127_5347726_1 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000003781 185.0
HKD2_k127_5347726_2 [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000004085 149.0
HKD2_k127_5367613_0 xanthine dehydrogenase activity - - - 3.573e-195 636.0
HKD2_k127_5367613_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 544.0
HKD2_k127_5367613_2 Amidohydrolase family K01487 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 323.0
HKD2_k127_5367613_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000884 173.0
HKD2_k127_5371260_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 376.0
HKD2_k127_5371260_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002909 278.0
HKD2_k127_5371260_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003298 252.0
HKD2_k127_5371260_3 rod shape-determining protein MreD K03571 - - 0.00003184 54.0
HKD2_k127_5386894_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 347.0
HKD2_k127_5386894_1 Secreted repeat of unknown function - - - 0.0000000000000000000000008028 119.0
HKD2_k127_5386894_2 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000001108 111.0
HKD2_k127_5386894_3 Hydrolase of the alpha beta-hydrolase K07020 - - 0.0000000000000000001372 96.0
HKD2_k127_5386894_4 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000006565 94.0
HKD2_k127_5386894_5 ABC-2 family transporter protein K01992 - - 0.0001727 48.0
HKD2_k127_5397947_0 Rieske-like [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000001138 204.0
HKD2_k127_5397947_1 Methyltransferase domain - - - 0.000000561 59.0
HKD2_k127_5415096_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000004756 210.0
HKD2_k127_5415096_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000004617 187.0
HKD2_k127_5415096_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002449 114.0
HKD2_k127_5415096_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000002534 102.0
HKD2_k127_5415096_4 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087,K16055 GO:0003674,GO:0003824,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044464,GO:0046351,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:1901576 2.4.1.15,3.1.3.12 0.0000008334 55.0
HKD2_k127_5438376_0 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000007813 196.0
HKD2_k127_5438376_1 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000009004 164.0
HKD2_k127_5438376_2 YCII-related domain K09780 - - 0.0000000000000000000000000000000004375 133.0
HKD2_k127_5438376_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000001181 107.0
HKD2_k127_5438376_4 -acetyltransferase - - - 0.00000000000003482 83.0
HKD2_k127_5438376_5 Nucleoside H+ symporter K05820 - - 0.0000871 55.0
HKD2_k127_5459935_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 314.0
HKD2_k127_5459935_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006239 308.0
HKD2_k127_5459935_10 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000001993 95.0
HKD2_k127_5459935_11 Acyl-ACP thioesterase - - - 0.000000004104 69.0
HKD2_k127_5459935_12 PFAM AAA ATPase central domain protein - - - 0.0001057 51.0
HKD2_k127_5459935_2 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003327 268.0
HKD2_k127_5459935_3 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001367 272.0
HKD2_k127_5459935_4 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000556 263.0
HKD2_k127_5459935_5 PFAM Receptor family ligand binding region K01999,K11954 - - 0.0000000000000000000000000000000000000000000000000000000003077 222.0
HKD2_k127_5459935_6 PFAM class II aldolase adducin family protein K01628,K03077 - 4.1.2.17,5.1.3.4 0.00000000000000000000000000000000001536 148.0
HKD2_k127_5459935_7 NYN domain - - - 0.00000000000000000000000000000000001879 155.0
HKD2_k127_5459935_8 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000001305 149.0
HKD2_k127_5459935_9 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000001083 112.0
HKD2_k127_5506780_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 324.0
HKD2_k127_5506780_1 TIGRFAM radical SAM additional 4Fe4S-binding domain K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 300.0
HKD2_k127_5506780_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005735 282.0
HKD2_k127_5506780_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000004102 216.0
HKD2_k127_5506780_4 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000006665 153.0
HKD2_k127_553883_0 carbohydrate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 441.0
HKD2_k127_553883_1 ABC transporter, transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 243.0
HKD2_k127_553883_2 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000004105 242.0
HKD2_k127_553883_3 Iron-binding zinc finger CDGSH type - - - 0.000000000001151 68.0
HKD2_k127_5547841_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.828e-195 623.0
HKD2_k127_5547841_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000001266 220.0
HKD2_k127_5547841_2 Ftsk_gamma - - - 0.00001178 58.0
HKD2_k127_5613924_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 4.173e-205 648.0
HKD2_k127_5613924_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 521.0
HKD2_k127_5613924_10 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000003923 136.0
HKD2_k127_5613924_11 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000004526 141.0
HKD2_k127_5613924_12 FMN binding - - - 0.000000000000000000000000001557 119.0
HKD2_k127_5613924_13 Ferric reductase like transmembrane component - - - 0.0000000000000000000000002262 123.0
HKD2_k127_5613924_14 integral membrane protein K00728 - 2.4.1.109 0.0000000000000000000000232 115.0
HKD2_k127_5613924_15 NADH ubiquinone oxidoreductase NADH-binding (51 kD) subunit - - - 0.0000000000000000000004974 100.0
HKD2_k127_5613924_16 Carbon-nitrogen hydrolase - - - 0.0002916 46.0
HKD2_k127_5613924_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 502.0
HKD2_k127_5613924_3 GtrA-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 448.0
HKD2_k127_5613924_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 445.0
HKD2_k127_5613924_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000004604 270.0
HKD2_k127_5613924_6 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.0000000000000000000000000000000000000000000000000005266 191.0
HKD2_k127_5613924_7 nitric oxide dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000001974 198.0
HKD2_k127_5613924_8 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000002284 133.0
HKD2_k127_5613924_9 protein histidine kinase activity - - - 0.00000000000000000000000000000001598 145.0
HKD2_k127_5646813_0 ROK family K00845 - 2.7.1.2 0.0000000000005537 80.0
HKD2_k127_5646813_1 - - - - 0.00000002517 65.0
HKD2_k127_5661056_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006003 287.0
HKD2_k127_5661056_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000003102 133.0
HKD2_k127_5661056_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000005183 75.0
HKD2_k127_5665894_0 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 399.0
HKD2_k127_5665894_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 286.0
HKD2_k127_5665894_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000007702 216.0
HKD2_k127_570539_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1589.0
HKD2_k127_570539_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 541.0
HKD2_k127_570539_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001077 172.0
HKD2_k127_570539_11 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000001341 154.0
HKD2_k127_570539_12 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000008831 117.0
HKD2_k127_570539_13 cyclic nucleotide binding K10914 - - 0.00000000000000005272 94.0
HKD2_k127_570539_14 Domain of unknown function (DUF1992) - - - 0.000000002808 66.0
HKD2_k127_570539_15 TIGRFAM integral membrane protein TIGR01906 - - - 0.0000000164 66.0
HKD2_k127_570539_16 Electron transfer flavoprotein K03522 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000005751 65.0
HKD2_k127_570539_17 Domain of unknown function (DUF4332) - - - 0.00007259 53.0
HKD2_k127_570539_2 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 537.0
HKD2_k127_570539_3 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 427.0
HKD2_k127_570539_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 338.0
HKD2_k127_570539_5 Molybdenum cofactor synthesis domain protein K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004727 285.0
HKD2_k127_570539_6 TIGRFAM Dyp-type peroxidase family K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001799 281.0
HKD2_k127_570539_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001277 185.0
HKD2_k127_570539_8 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000000000000000000000000000000000000000001269 184.0
HKD2_k127_570539_9 Protein of unknown function (DUF1269) - - - 0.000000000000000000000000000000000000000000000002337 181.0
HKD2_k127_5714414_0 DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000205 171.0
HKD2_k127_5714414_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000002446 110.0
HKD2_k127_5714414_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000004394 93.0
HKD2_k127_5714414_3 EamA-like transporter family - - - 0.00000000003846 74.0
HKD2_k127_572954_0 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 315.0
HKD2_k127_572954_1 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 302.0
HKD2_k127_5730045_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 441.0
HKD2_k127_5730045_1 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000005166 211.0
HKD2_k127_5730045_2 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000003055 162.0
HKD2_k127_5730045_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000004086 105.0
HKD2_k127_5740210_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1152.0
HKD2_k127_5740210_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 338.0
HKD2_k127_5740210_2 Serine threonine protein kinase involved in cell cycle control - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 307.0
HKD2_k127_5740210_3 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 290.0
HKD2_k127_5740210_4 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005849 255.0
HKD2_k127_5740210_5 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000001686 214.0
HKD2_k127_5740210_6 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000001979 197.0
HKD2_k127_5740210_7 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000001358 196.0
HKD2_k127_5740210_8 His Kinase A (phosphoacceptor) domain K14982 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000003812 198.0
HKD2_k127_5740210_9 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000000000000004669 152.0
HKD2_k127_5754760_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 3.15e-196 649.0
HKD2_k127_5754760_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 505.0
HKD2_k127_5754760_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 323.0
HKD2_k127_5754760_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004966 274.0
HKD2_k127_5754760_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564 2.1.2.2 0.00000000000000000000000000000006251 130.0
HKD2_k127_5754760_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000375 74.0
HKD2_k127_5758658_0 NAD synthase K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006796 283.0
HKD2_k127_5758658_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000002948 212.0
HKD2_k127_5758658_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0002881 46.0
HKD2_k127_5765129_0 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 343.0
HKD2_k127_5765129_1 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 294.0
HKD2_k127_5765129_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - 0.00000000000000000000000000000000000000000000000000003022 202.0
HKD2_k127_5765129_3 Domain of unknown function (DU1801) - - - 0.0000000000000008844 82.0
HKD2_k127_57821_0 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 614.0
HKD2_k127_57821_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
HKD2_k127_57821_2 - - - - 0.00000000000000000000000000000000006246 143.0
HKD2_k127_57821_3 lysyltransferase activity - - - 0.00000000000000000000002523 113.0
HKD2_k127_5826624_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 473.0
HKD2_k127_5826624_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 451.0
HKD2_k127_5826624_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 327.0
HKD2_k127_583017_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system - - - 9.543e-242 792.0
HKD2_k127_583017_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.77e-205 656.0
HKD2_k127_585407_0 Sulfate permease K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 424.0
HKD2_k127_5913402_0 dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 429.0
HKD2_k127_5913402_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 419.0
HKD2_k127_5913402_2 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 321.0
HKD2_k127_5913402_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000003838 174.0
HKD2_k127_5963466_0 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000153 234.0
HKD2_k127_5963466_1 Cupredoxin-like domain - - - 0.00006916 51.0
HKD2_k127_602417_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000005384 179.0
HKD2_k127_6161186_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 444.0
HKD2_k127_6161186_1 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002349 273.0
HKD2_k127_6161186_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000397 197.0
HKD2_k127_6161186_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000009561 171.0
HKD2_k127_6161186_4 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000002702 140.0
HKD2_k127_6161186_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000004256 118.0
HKD2_k127_6161186_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001918 85.0
HKD2_k127_6161186_7 negative regulation of DNA recombination - - - 0.000003143 56.0
HKD2_k127_6389271_0 L-valine transmembrane transporter activity - - - 0.0000000000000000000000000000000008458 143.0
HKD2_k127_6406630_0 acetyltransferase - - - 0.0000000000000000000000000000000000000005462 161.0
HKD2_k127_6406630_1 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000008844 119.0
HKD2_k127_6414421_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 299.0
HKD2_k127_6414421_1 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000004333 241.0
HKD2_k127_6414421_2 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.00000000000000002031 83.0
HKD2_k127_6418635_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.499e-219 691.0
HKD2_k127_6418635_1 AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.428e-211 672.0
HKD2_k127_6418635_10 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658,K09699 - 2.3.1.12,2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 343.0
HKD2_k127_6418635_11 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 306.0
HKD2_k127_6418635_12 Binding-protein-dependent transport system inner membrane component K15599 - - 0.000000000000000000000000000000000000000000000000000000000000291 214.0
HKD2_k127_6418635_13 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000001585 218.0
HKD2_k127_6418635_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000001865 200.0
HKD2_k127_6418635_15 WD40 domain protein beta Propeller K03641 - - 0.00000000000000000000000000000000000004621 164.0
HKD2_k127_6418635_16 PFAM regulatory protein, ArsR - - - 0.000000000000000000000000000000000000548 151.0
HKD2_k127_6418635_17 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000006403 132.0
HKD2_k127_6418635_18 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000002536 138.0
HKD2_k127_6418635_19 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000553 133.0
HKD2_k127_6418635_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 641.0
HKD2_k127_6418635_3 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 580.0
HKD2_k127_6418635_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 468.0
HKD2_k127_6418635_5 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 461.0
HKD2_k127_6418635_6 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 382.0
HKD2_k127_6418635_7 Dehydrogenase E1 component K00166 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 374.0
HKD2_k127_6418635_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 358.0
HKD2_k127_6418635_9 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 357.0
HKD2_k127_6420302_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 4.709e-266 863.0
HKD2_k127_6420302_1 PFAM Helicase conserved C-terminal domain K06877 - - 3.583e-260 824.0
HKD2_k127_6420302_10 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000258 220.0
HKD2_k127_6420302_11 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000003111 194.0
HKD2_k127_6420302_12 Methyltransferase type 12 - - - 0.00000000000000000000000000000002746 143.0
HKD2_k127_6420302_13 Pilus assembly protein K02282 - - 0.00000000000000000000000002809 122.0
HKD2_k127_6420302_14 Belongs to the phosphoglycerate mutase family - - - 0.00000000000000000000402 104.0
HKD2_k127_6420302_15 Protein of unknown function (DUF4446) - - - 0.000000000000000000007976 101.0
HKD2_k127_6420302_16 PFAM PfkB domain protein - - - 0.00000000000004143 84.0
HKD2_k127_6420302_17 HAD-hyrolase-like K20862 - 3.1.3.102,3.1.3.104 0.000000003338 70.0
HKD2_k127_6420302_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 471.0
HKD2_k127_6420302_3 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 454.0
HKD2_k127_6420302_4 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 395.0
HKD2_k127_6420302_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 355.0
HKD2_k127_6420302_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 302.0
HKD2_k127_6420302_7 Peptidase dimerisation domain K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 278.0
HKD2_k127_6420302_8 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002772 263.0
HKD2_k127_6420302_9 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004501 252.0
HKD2_k127_6421503_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 567.0
HKD2_k127_6421503_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 524.0
HKD2_k127_6421503_10 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000002746 238.0
HKD2_k127_6421503_11 - - - - 0.000000000000000000000000000000000000000000000003617 194.0
HKD2_k127_6421503_12 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000048 169.0
HKD2_k127_6421503_13 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000001728 147.0
HKD2_k127_6421503_14 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000007097 138.0
HKD2_k127_6421503_15 - K01992 - - 0.000000000000000000000000000001897 140.0
HKD2_k127_6421503_16 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000002876 111.0
HKD2_k127_6421503_17 AI-2E family transporter - - - 0.0000000000000000322 96.0
HKD2_k127_6421503_18 methionine synthase K00548 - 2.1.1.13 0.0000000000000008876 86.0
HKD2_k127_6421503_19 CYTH K01768 - 4.6.1.1 0.00000000001091 74.0
HKD2_k127_6421503_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 477.0
HKD2_k127_6421503_3 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 464.0
HKD2_k127_6421503_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 406.0
HKD2_k127_6421503_5 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 383.0
HKD2_k127_6421503_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 325.0
HKD2_k127_6421503_7 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000004016 236.0
HKD2_k127_6421503_8 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
HKD2_k127_6421503_9 hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000051 224.0
HKD2_k127_6431851_0 Osmosensitive K+ channel His kinase sensor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 302.0
HKD2_k127_6431851_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000004722 218.0
HKD2_k127_6431851_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0000000000000000000003764 96.0
HKD2_k127_6443848_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 622.0
HKD2_k127_6443848_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 483.0
HKD2_k127_6443848_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000008399 150.0
HKD2_k127_6443848_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000137 141.0
HKD2_k127_6443848_12 Trp repressor protein - - - 0.000000000000000000003403 96.0
HKD2_k127_6443848_13 Modulates RecA activity K03565 - - 0.0000000000000007751 85.0
HKD2_k127_6443848_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 420.0
HKD2_k127_6443848_3 Queuine tRNA-ribosyltransferase K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007916 377.0
HKD2_k127_6443848_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 354.0
HKD2_k127_6443848_5 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004213 274.0
HKD2_k127_6443848_6 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000002126 243.0
HKD2_k127_6443848_7 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000001913 197.0
HKD2_k127_6443848_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000004426 179.0
HKD2_k127_6443848_9 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000007938 175.0
HKD2_k127_6447842_0 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 541.0
HKD2_k127_6447842_1 Tryptophan/tyrosine permease family - - - 0.0000000000000000000000000000000000000000000000000000001331 205.0
HKD2_k127_6447842_2 - - - - 0.0000000000000000000000000000001882 140.0
HKD2_k127_6457954_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001511 277.0
HKD2_k127_6457954_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004483 262.0
HKD2_k127_6457954_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000863 216.0
HKD2_k127_6457954_3 Short C-terminal domain K08982 - - 0.0000004287 56.0
HKD2_k127_6457954_4 diacylglycerol kinase catalytic domain protein - - - 0.0001496 44.0
HKD2_k127_6471703_0 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 483.0
HKD2_k127_6471703_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 462.0
HKD2_k127_6471703_2 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000001928 254.0
HKD2_k127_6471703_3 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000001194 196.0
HKD2_k127_6471703_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000003118 179.0
HKD2_k127_6471703_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000005788 111.0
HKD2_k127_6471703_6 amine dehydrogenase activity - - - 0.000000000000000000004732 109.0
HKD2_k127_6471703_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00007118 52.0
HKD2_k127_6471703_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000792 51.0
HKD2_k127_6475077_0 ATPases associated with a variety of cellular activities K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001036 277.0
HKD2_k127_6475077_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000006232 277.0
HKD2_k127_6475077_2 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.0000000000000000000000000000000000000001173 162.0
HKD2_k127_6475077_3 Acetyltransferase (GNAT) family - - - 0.000000000000004726 84.0
HKD2_k127_6479558_0 COGs COG3367 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 321.0
HKD2_k127_6479558_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009205 277.0
HKD2_k127_6479558_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000005368 254.0
HKD2_k127_6479558_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000004354 213.0
HKD2_k127_6479558_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000005653 137.0
HKD2_k127_6479558_5 - - - - 0.00000007087 61.0
HKD2_k127_6514414_0 von Willebrand factor (vWF) type A domain - - - 1.354e-195 640.0
HKD2_k127_6514414_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 607.0
HKD2_k127_6514414_2 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 465.0
HKD2_k127_6514414_3 Periplasmic binding protein domain K10546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 376.0
HKD2_k127_6514414_4 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 303.0
HKD2_k127_6514414_5 - - - - 0.000000000000000000000000000000000000000000009936 175.0
HKD2_k127_6514414_6 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.00000000000000000000002098 116.0
HKD2_k127_6547829_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K00058,K03977 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 306.0
HKD2_k127_6547829_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000003095 247.0
HKD2_k127_6573423_0 CoA-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 384.0
HKD2_k127_6573423_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009519 264.0
HKD2_k127_6573423_2 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000002084 238.0
HKD2_k127_6573423_3 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000007982 205.0
HKD2_k127_6573423_4 Ferric reductase like transmembrane component K17247 - - 0.000000000000000000000000000000008563 139.0
HKD2_k127_6573423_5 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000000000006324 85.0
HKD2_k127_6577875_0 Cys/Met metabolism PLP-dependent enzyme K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
HKD2_k127_6577875_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
HKD2_k127_6577875_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01761 - 4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 325.0
HKD2_k127_6577875_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 317.0
HKD2_k127_6577875_4 AsnC family K03718 - - 0.000000000000000000000000000000000000000000000001742 178.0
HKD2_k127_6577875_5 Glycosyl transferases group 1 K16150 - 2.4.1.11 0.0000000000000000000000000000000000000003814 170.0
HKD2_k127_6577875_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000003792 161.0
HKD2_k127_6577875_7 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000002728 150.0
HKD2_k127_6614907_0 Acylphosphatase K04656 - - 1.557e-262 837.0
HKD2_k127_6614907_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.474e-258 810.0
HKD2_k127_6614907_10 HupF/HypC family K04653 - - 0.0000000000000000000000000007125 117.0
HKD2_k127_6614907_11 Sulfurtransferase TusA - - - 0.0000000000000000000007009 98.0
HKD2_k127_6614907_12 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000008513 103.0
HKD2_k127_6614907_13 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000009855 91.0
HKD2_k127_6614907_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000003859 79.0
HKD2_k127_6614907_15 Protein of unknown function (DUF1634) - - - 0.0000006295 55.0
HKD2_k127_6614907_16 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0004414 48.0
HKD2_k127_6614907_2 hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 585.0
HKD2_k127_6614907_3 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 446.0
HKD2_k127_6614907_4 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 402.0
HKD2_k127_6614907_5 Short-chain dehydrogenase reductase sdr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 340.0
HKD2_k127_6614907_6 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000000000000000000000000000000000000001705 205.0
HKD2_k127_6614907_7 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000005982 169.0
HKD2_k127_6614907_8 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000001382 166.0
HKD2_k127_6614907_9 hydrogenase maturation protease K03605 - - 0.0000000000000000000000000001013 132.0
HKD2_k127_6616781_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 546.0
HKD2_k127_6616781_1 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 412.0
HKD2_k127_6616781_2 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009853 284.0
HKD2_k127_6616781_3 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000002211 155.0
HKD2_k127_6616781_4 Mov34 MPN PAD-1 family K21140 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016787,GO:0019344,GO:0019538,GO:0019752,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.13.1.6 0.00008325 55.0
HKD2_k127_6625449_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 524.0
HKD2_k127_6625449_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 468.0
HKD2_k127_6625449_2 Phosphotriesterase family K07048 - - 0.00000000000000000000000000000000000000000000000000000000000000000009422 242.0
HKD2_k127_6625449_3 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000002989 164.0
HKD2_k127_6625449_4 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000006967 155.0
HKD2_k127_6637104_0 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 496.0
HKD2_k127_6637104_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 440.0
HKD2_k127_6637104_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 335.0
HKD2_k127_6641866_0 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 342.0
HKD2_k127_6641866_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002719 267.0
HKD2_k127_6641866_2 binding-protein-dependent transport systems inner membrane component K02038 - - 0.00000000000000000000000000000000000000000003927 169.0
HKD2_k127_6648049_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.579e-243 762.0
HKD2_k127_6648049_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.027e-220 709.0
HKD2_k127_6648049_10 PFAM DinB family protein - - - 0.0000000000000000000004411 102.0
HKD2_k127_6648049_11 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000002737 108.0
HKD2_k127_6648049_12 HAD-hyrolase-like - - - 0.00000000000000000000792 96.0
HKD2_k127_6648049_13 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000003115 98.0
HKD2_k127_6648049_14 PFAM Phospholipid glycerol acyltransferase - - - 0.0000000000000000005398 99.0
HKD2_k127_6648049_15 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.000000000000000001119 97.0
HKD2_k127_6648049_16 Biotin lipoyl attachment domain-containing protein - - - 0.000000000318 74.0
HKD2_k127_6648049_2 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 500.0
HKD2_k127_6648049_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 423.0
HKD2_k127_6648049_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 389.0
HKD2_k127_6648049_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 338.0
HKD2_k127_6648049_6 Cellulose biosynthesis protein BcsQ K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002457 237.0
HKD2_k127_6648049_7 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000001216 166.0
HKD2_k127_6648049_8 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000111 159.0
HKD2_k127_6648049_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000001798 135.0
HKD2_k127_6656547_0 COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 353.0
HKD2_k127_6656547_1 Periplasmic binding protein domain K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 329.0
HKD2_k127_6656547_2 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 327.0
HKD2_k127_6656547_3 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000473 278.0
HKD2_k127_6656547_4 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000007599 138.0
HKD2_k127_6656547_5 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.00000000444 68.0
HKD2_k127_6679987_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 355.0
HKD2_k127_6679987_1 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.0000000000000000000000000000000000000000000000000001291 194.0
HKD2_k127_6708846_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.514e-207 661.0
HKD2_k127_6708846_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 604.0
HKD2_k127_6708846_10 Protein of unknown function (DUF448) K07742 - - 0.0000000000000002263 87.0
HKD2_k127_6708846_11 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000217 58.0
HKD2_k127_6708846_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 379.0
HKD2_k127_6708846_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 338.0
HKD2_k127_6708846_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000004567 213.0
HKD2_k127_6708846_5 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.00000000000000000000000000000000000000000000000000027 198.0
HKD2_k127_6708846_6 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000001029 181.0
HKD2_k127_6708846_7 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000964 143.0
HKD2_k127_6708846_8 Riboflavin kinase K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000004474 122.0
HKD2_k127_6708846_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000002105 117.0
HKD2_k127_671739_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 460.0
HKD2_k127_671739_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000001797 180.0
HKD2_k127_671739_2 COG2017 Galactose mutarotase and related enzymes K01785 - 5.1.3.3 0.000000000000000000000002974 113.0
HKD2_k127_671739_3 proline dipeptidase activity - - - 0.000215 44.0
HKD2_k127_6731979_0 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002065 280.0
HKD2_k127_6731979_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000002822 208.0
HKD2_k127_6739638_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 447.0
HKD2_k127_6739638_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000007982 254.0
HKD2_k127_6739638_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000004696 222.0
HKD2_k127_6766054_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 482.0
HKD2_k127_6766054_1 Putative FMN-binding domain K07734 - - 0.00000001899 57.0
HKD2_k127_6767058_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1204.0
HKD2_k127_6767058_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.11e-230 740.0
HKD2_k127_6767058_10 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000005965 183.0
HKD2_k127_6767058_11 Sulfurtransferase TusA - - - 0.000000000000000000000000827 105.0
HKD2_k127_6767058_12 - K06039,K07092 - - 0.000000000000000000000003729 106.0
HKD2_k127_6767058_13 DsrE/DsrF-like family - - - 0.0000000000000000000605 94.0
HKD2_k127_6767058_14 Thioredoxin domain - - - 0.0000000000000000001453 101.0
HKD2_k127_6767058_15 Hemerythrin HHE cation binding domain - - - 0.00000000000000001708 88.0
HKD2_k127_6767058_16 - - - - 0.00000000000000007325 92.0
HKD2_k127_6767058_17 Transcriptional regulator - - - 0.00000000000002093 77.0
HKD2_k127_6767058_18 Hemerythrin HHE cation binding domain - - - 0.00000000000008896 85.0
HKD2_k127_6767058_19 Transcriptional regulator - - - 0.0000000000002032 81.0
HKD2_k127_6767058_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 460.0
HKD2_k127_6767058_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000003186 63.0
HKD2_k127_6767058_21 - - - - 0.00002002 55.0
HKD2_k127_6767058_22 - - - - 0.0000405 53.0
HKD2_k127_6767058_3 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 380.0
HKD2_k127_6767058_4 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002808 284.0
HKD2_k127_6767058_5 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000004468 216.0
HKD2_k127_6767058_6 Transcriptional regulatory protein, C terminal K02483,K07658,K07668 - - 0.000000000000000000000000000000000000000000000000000000000227 211.0
HKD2_k127_6767058_7 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000002175 204.0
HKD2_k127_6767058_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000006303 204.0
HKD2_k127_6812740_0 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 390.0
HKD2_k127_6812740_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 340.0
HKD2_k127_6812740_2 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005113 263.0
HKD2_k127_6812740_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000003667 240.0
HKD2_k127_6812740_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000004218 213.0
HKD2_k127_6812740_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000327 178.0
HKD2_k127_6812740_6 May be required for sporulation K09762 - - 0.0000000000000000000007363 106.0
HKD2_k127_6812740_7 protein secretion K03116,K03117,K03646 - - 0.000000000000001653 84.0
HKD2_k127_6812740_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000004317 61.0
HKD2_k127_6897608_0 Belongs to the FPG family K05522 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000001354 244.0
HKD2_k127_6897608_1 DEAD DEAH box K03724 - - 0.00000000000000000000000000000000000000000239 162.0
HKD2_k127_6897608_2 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000006167 164.0
HKD2_k127_6897608_3 - - - - 0.0000000009468 70.0
HKD2_k127_6897608_4 glutamine amidotransferase K07008 - 3.5.1.118 0.00003546 55.0
HKD2_k127_69082_0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000006261 262.0
HKD2_k127_69082_1 electron transfer flavoprotein, alpha subunit K03522 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001156 186.0
HKD2_k127_69082_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000004643 177.0
HKD2_k127_69082_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000001416 162.0
HKD2_k127_69082_4 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000005977 156.0
HKD2_k127_69082_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000003075 124.0
HKD2_k127_69082_6 Glutaredoxin-like domain (DUF836) - - - 0.000002193 56.0
HKD2_k127_6955185_0 PFAM Chlorite dismutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000007438 241.0
HKD2_k127_6955185_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000002501 193.0
HKD2_k127_6955185_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000005377 133.0
HKD2_k127_6955185_3 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K03496,K22491 - - 0.00000000000000000000005316 108.0
HKD2_k127_6955185_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000006926 100.0
HKD2_k127_6955185_5 - - - - 0.00006374 53.0
HKD2_k127_6974728_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000002413 173.0
HKD2_k127_6974728_1 Kelch - - - 0.00000000000000000000000000000000000000000004016 179.0
HKD2_k127_6974728_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000005966 59.0
HKD2_k127_7067989_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000002355 181.0
HKD2_k127_7067989_1 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000001137 155.0
HKD2_k127_7067989_2 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000003631 126.0
HKD2_k127_710662_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 406.0
HKD2_k127_710662_2 Sulfate transporter K03321 - - 0.0000000001276 64.0
HKD2_k127_710662_3 Carboxymuconolactone decarboxylase family - - - 0.00000003724 63.0
HKD2_k127_7112085_0 PolyA polymerase K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 330.0
HKD2_k127_7112085_1 SMART HNH nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000002017 216.0
HKD2_k127_7112085_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000005997 111.0
HKD2_k127_7112085_3 Biotin carboxylase C-terminal domain K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.00000002709 57.0
HKD2_k127_7112085_4 COG3118 Thioredoxin domain-containing protein K03671,K05838 - - 0.0001681 52.0
HKD2_k127_7377309_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 473.0
HKD2_k127_7377309_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 353.0
HKD2_k127_73963_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 341.0
HKD2_k127_73963_1 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
HKD2_k127_73963_2 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003046 276.0
HKD2_k127_73963_3 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002634 277.0
HKD2_k127_73963_4 regulatory protein - - - 0.000000000000000000000000000000000000000002611 177.0
HKD2_k127_75522_0 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 582.0
HKD2_k127_75522_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 526.0
HKD2_k127_75522_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 466.0
HKD2_k127_75522_3 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 395.0
HKD2_k127_7610249_0 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 481.0
HKD2_k127_7610249_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 313.0
HKD2_k127_7610249_2 Putative sensor - - - 0.000000000000000000000000000000000000000000000000000000000001264 235.0
HKD2_k127_7610249_4 - - - - 0.00000000000000005934 85.0
HKD2_k127_766331_0 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 383.0
HKD2_k127_766331_1 FAD dependent oxidoreductase - - - 0.0000000000000000001237 91.0
HKD2_k127_7667929_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 556.0
HKD2_k127_7667929_1 DinB family K18843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 321.0
HKD2_k127_7667929_2 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000001817 240.0
HKD2_k127_7667929_3 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000000000000009937 125.0
HKD2_k127_7667929_4 Domain of unknown function (DUF4445) - - - 0.000000000006677 68.0
HKD2_k127_7670327_0 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 398.0
HKD2_k127_7670327_1 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000929 297.0
HKD2_k127_7670327_2 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000868 251.0
HKD2_k127_7670327_3 response regulator receiver K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000002814 229.0
HKD2_k127_7670327_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000007582 195.0
HKD2_k127_7670327_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000004121 165.0
HKD2_k127_7670327_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000003427 142.0
HKD2_k127_7670327_7 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000001055 113.0
HKD2_k127_7670327_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000008522 82.0
HKD2_k127_7670398_0 PFAM oxidoreductase molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 419.0
HKD2_k127_7678830_0 Flavin containing amine oxidoreductase - - - 2.987e-242 758.0
HKD2_k127_7678830_1 Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 442.0
HKD2_k127_7678830_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 440.0
HKD2_k127_7678830_3 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 451.0
HKD2_k127_7678830_4 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 347.0
HKD2_k127_7678830_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000003028 264.0
HKD2_k127_7678830_6 Abc transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000001768 161.0
HKD2_k127_7678830_7 permease - - - 0.0000000000000000002396 102.0
HKD2_k127_7678830_8 O-Antigen ligase - - - 0.00001334 58.0
HKD2_k127_7688115_0 Conserved protein containing a Zn-ribbon-like motif - - - 0.00000000000000000004118 98.0
HKD2_k127_7690751_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 1.098e-266 837.0
HKD2_k127_7690751_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 314.0
HKD2_k127_7690751_2 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000007757 232.0
HKD2_k127_7690751_3 Thioesterase superfamily - - - 0.00000000000000000000001168 110.0
HKD2_k127_7692182_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 359.0
HKD2_k127_7692182_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004623 290.0
HKD2_k127_7692182_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000008402 190.0
HKD2_k127_7692182_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000007334 151.0
HKD2_k127_7692182_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000001954 109.0
HKD2_k127_7692182_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000002247 107.0
HKD2_k127_7692182_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.00000000001054 78.0
HKD2_k127_7704031_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 589.0
HKD2_k127_7704031_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000005099 196.0
HKD2_k127_7704031_2 CHAD - - - 0.0000000000000000000000000000000000000009283 165.0
HKD2_k127_7704031_3 CYTH - - - 0.00000001523 64.0
HKD2_k127_7704236_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006148 263.0
HKD2_k127_7704236_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000275 280.0
HKD2_k127_7704236_2 YbaB/EbfC DNA-binding family K09747 - - 0.00000000000000000000000000181 118.0
HKD2_k127_7704236_3 - - - - 0.0000000000000000000003889 99.0
HKD2_k127_7715829_0 phospholipase C - - - 0.00000000000000000000000000000000000000000000000000000001551 210.0
HKD2_k127_7715829_1 PFAM GCN5-related N-acetyltransferase - - - 0.00000001556 60.0
HKD2_k127_7715829_2 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.0007961 44.0
HKD2_k127_7718048_0 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 295.0
HKD2_k127_7718048_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000001551 211.0
HKD2_k127_7721447_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 454.0
HKD2_k127_7723721_0 F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000007353 207.0
HKD2_k127_7723721_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000001634 113.0
HKD2_k127_7723721_3 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.000000000000003412 77.0
HKD2_k127_77263_0 Zn peptidase - - - 0.00000000000000000000000000000000000000000000000000001394 203.0
HKD2_k127_77263_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000003969 162.0
HKD2_k127_7732712_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 392.0
HKD2_k127_7732712_1 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 335.0
HKD2_k127_7732712_2 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
HKD2_k127_7732712_3 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000001762 204.0
HKD2_k127_7738020_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 420.0
HKD2_k127_7747594_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
HKD2_k127_7747594_1 Belongs to the OMP decarboxylase family. Type 2 subfamily - - - 0.00000000000000000000000000000000000000001758 161.0
HKD2_k127_7748728_0 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 451.0
HKD2_k127_7748728_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 394.0
HKD2_k127_7748728_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 375.0
HKD2_k127_7748728_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000002519 214.0
HKD2_k127_7748728_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000002717 181.0
HKD2_k127_7748728_5 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000002895 100.0
HKD2_k127_7748728_6 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0001278 54.0
HKD2_k127_7750522_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 573.0
HKD2_k127_7750522_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 430.0
HKD2_k127_7750522_2 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
HKD2_k127_7755207_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 384.0
HKD2_k127_7765749_0 Glyco_18 K01448,K07260,K20276 - 3.4.17.14,3.5.1.28 0.000000000000000000000000000000002734 147.0
HKD2_k127_7765749_1 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000003453 121.0
HKD2_k127_7770084_0 ABC transporter, transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000001669 211.0
HKD2_k127_7770084_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000002289 175.0
HKD2_k127_7771978_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 516.0
HKD2_k127_7771978_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 305.0
HKD2_k127_7771978_2 PFAM Enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000768 269.0
HKD2_k127_7771978_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000006926 140.0
HKD2_k127_7771978_4 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.00000000000000000000273 106.0
HKD2_k127_7771978_5 Belongs to the UPF0354 family - - - 0.000007193 59.0
HKD2_k127_7773654_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 599.0
HKD2_k127_7773654_1 Quinone oxidoreductase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 341.0
HKD2_k127_7773654_2 NMT1/THI5 like K15598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000146 280.0
HKD2_k127_7773654_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000002783 244.0
HKD2_k127_7773654_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000007109 72.0
HKD2_k127_7786364_0 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000000000000000000000000000000007555 168.0
HKD2_k127_7786364_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000002411 161.0
HKD2_k127_7786364_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000004374 70.0
HKD2_k127_7788220_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 514.0
HKD2_k127_7788220_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000001238 161.0
HKD2_k127_7788220_2 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000001831 165.0
HKD2_k127_7793545_0 Serine carboxypeptidase - - - 3.965e-223 702.0
HKD2_k127_7793545_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 408.0
HKD2_k127_7793545_2 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000001137 239.0
HKD2_k127_7793545_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000002298 213.0
HKD2_k127_7793545_4 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000001348 187.0
HKD2_k127_7793545_5 ethyl tert-butyl ether degradation - - - 0.000000000000000000000000000001605 124.0
HKD2_k127_7793545_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.0000000001991 64.0
HKD2_k127_7793545_7 SnoaL-like domain - - - 0.00005496 50.0
HKD2_k127_7799424_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 614.0
HKD2_k127_7799424_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 445.0
HKD2_k127_7799424_10 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000002183 147.0
HKD2_k127_7799424_11 - - - - 0.000000000000000000293 92.0
HKD2_k127_7799424_12 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000009404 76.0
HKD2_k127_7799424_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 373.0
HKD2_k127_7799424_3 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 375.0
HKD2_k127_7799424_4 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000001353 274.0
HKD2_k127_7799424_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000003698 231.0
HKD2_k127_7799424_6 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000002215 216.0
HKD2_k127_7799424_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000001658 214.0
HKD2_k127_7799424_8 - - - - 0.000000000000000000000000000000000000000000000006497 189.0
HKD2_k127_7799424_9 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000181 170.0
HKD2_k127_7826149_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 1.646e-199 635.0
HKD2_k127_7830742_0 Evidence 5 No homology to any previously reported sequences - - - 1.428e-276 870.0
HKD2_k127_7830742_1 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 531.0
HKD2_k127_7830742_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
HKD2_k127_7830742_11 phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000945 224.0
HKD2_k127_7830742_12 oxidoreductase activity K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.000000000000000000000000000000000006226 156.0
HKD2_k127_7830742_13 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000001333 131.0
HKD2_k127_7830742_14 EamA-like transporter family - - - 0.00000000000000000003701 102.0
HKD2_k127_7830742_15 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000001131 68.0
HKD2_k127_7830742_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 512.0
HKD2_k127_7830742_3 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 477.0
HKD2_k127_7830742_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 436.0
HKD2_k127_7830742_5 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 437.0
HKD2_k127_7830742_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 395.0
HKD2_k127_7830742_7 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 387.0
HKD2_k127_7830742_8 branched-chain amino acid transmembrane transporter activity K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 306.0
HKD2_k127_7830742_9 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 300.0
HKD2_k127_7842762_0 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003026 276.0
HKD2_k127_7842762_1 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000002418 250.0
HKD2_k127_7842762_2 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000006984 186.0
HKD2_k127_7859087_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 606.0
HKD2_k127_7859087_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000407 145.0
HKD2_k127_7859730_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 385.0
HKD2_k127_7859730_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000009093 250.0
HKD2_k127_7859730_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000002217 127.0
HKD2_k127_7859730_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000007302 116.0
HKD2_k127_7863510_0 Belongs to the aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 304.0
HKD2_k127_7863510_1 Bacterial regulatory proteins, tetR family - - - 0.0000001246 53.0
HKD2_k127_7879863_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 588.0
HKD2_k127_7879863_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 431.0
HKD2_k127_7879863_10 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000002242 58.0
HKD2_k127_7879863_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001187 246.0
HKD2_k127_7879863_3 Competence protein ComEC K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000236 267.0
HKD2_k127_7879863_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000001162 216.0
HKD2_k127_7879863_5 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000003939 207.0
HKD2_k127_7879863_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000004925 198.0
HKD2_k127_7879863_7 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000001596 178.0
HKD2_k127_7879863_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000002058 129.0
HKD2_k127_7879863_9 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000003836 110.0
HKD2_k127_7879869_0 Orn Lys Arg decarboxylase K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 378.0
HKD2_k127_7879869_1 Mur ligase, middle domain - - - 0.00000000000000000000000000000003666 138.0
HKD2_k127_7880397_0 malic protein domain protein K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 595.0
HKD2_k127_7880397_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 503.0
HKD2_k127_7880397_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002265 306.0
HKD2_k127_7880397_3 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000007475 148.0
HKD2_k127_7880397_4 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000003639 106.0
HKD2_k127_7880397_5 Belongs to the universal stress protein A family - - - 0.0000000006067 67.0
HKD2_k127_7880397_6 COG1196 Chromosome segregation ATPases - - - 0.000000001037 65.0
HKD2_k127_7883992_0 Zinc-binding dehydrogenase K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 295.0
HKD2_k127_7883992_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 282.0
HKD2_k127_7883992_10 - - - - 0.0000000000000000000000000000219 129.0
HKD2_k127_7883992_11 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000007479 91.0
HKD2_k127_7883992_12 positive regulation of chromatin silencing at rDNA K02887,K09578 GO:0000122,GO:0000413,GO:0000993,GO:0001098,GO:0001099,GO:0001817,GO:0001818,GO:0001932,GO:0001933,GO:0001934,GO:0003674,GO:0003755,GO:0003774,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006325,GO:0006351,GO:0006353,GO:0006355,GO:0006357,GO:0006366,GO:0006369,GO:0006396,GO:0006397,GO:0006457,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0007088,GO:0007275,GO:0007346,GO:0007399,GO:0008013,GO:0008150,GO:0008152,GO:0008213,GO:0009058,GO:0009059,GO:0009405,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0016043,GO:0016070,GO:0016071,GO:0016462,GO:0016569,GO:0016570,GO:0016571,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016859,GO:0017015,GO:0017111,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018208,GO:0018995,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0023051,GO:0023056,GO:0023057,GO:0030111,GO:0030154,GO:0030162,GO:0030177,GO:0030182,GO:0030430,GO:0030496,GO:0030512,GO:0031056,GO:0031057,GO:0031063,GO:0031064,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031334,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031434,GO:0031647,GO:0031935,GO:0031937,GO:0031974,GO:0031981,GO:0032091,GO:0032092,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032465,GO:0032479,GO:0032480,GO:0032501,GO:0032502,GO:0032774,GO:0032784,GO:0032794,GO:0032879,GO:0032880,GO:0033043,GO:0033044,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034243,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035821,GO:0036211,GO:0040012,GO:0040013,GO:0042025,GO:0042176,GO:0042177,GO:0042325,GO:0042326,GO:0042327,GO:0043085,GO:0043087,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043393,GO:0043408,GO:0043409,GO:0043412,GO:0043414,GO:0043547,GO:0043656,GO:0043657,GO:0044003,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045309,GO:0045861,GO:0045892,GO:0045893,GO:0045898,GO:0045899,GO:0045934,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050815,GO:0050816,GO:0050821,GO:0051098,GO:0051099,GO:0051100,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051219,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051271,GO:0051276,GO:0051302,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051438,GO:0051443,GO:0051568,GO:0051701,GO:0051704,GO:0051726,GO:0051783,GO:0051817,GO:0060255,GO:0060260,GO:0060261,GO:0060341,GO:0060393,GO:0060828,GO:0060968,GO:0061187,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070063,GO:0070372,GO:0070373,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:0090092,GO:0090101,GO:0090263,GO:0090287,GO:0090288,GO:0090304,GO:0090311,GO:0097659,GO:0140096,GO:1900180,GO:1901360,GO:1901362,GO:1901407,GO:1901564,GO:1901576,GO:1901796,GO:1902275,GO:1902531,GO:1902532,GO:1902679,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903322,GO:1903362,GO:1903363,GO:1903506,GO:1903507,GO:1903508,GO:1903827,GO:1903844,GO:1903845,GO:1905268,GO:1905269,GO:2000058,GO:2000059,GO:2000112,GO:2000113,GO:2000142,GO:2000144,GO:2000145,GO:2000146,GO:2000749,GO:2001141,GO:2001251,GO:2001252 5.2.1.8 0.000000000001191 82.0
HKD2_k127_7883992_13 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000002287 70.0
HKD2_k127_7883992_14 SurA N-terminal domain - - - 0.00000001083 69.0
HKD2_k127_7883992_2 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000002832 243.0
HKD2_k127_7883992_3 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000002417 231.0
HKD2_k127_7883992_4 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000002039 218.0
HKD2_k127_7883992_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000008539 191.0
HKD2_k127_7883992_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000001148 182.0
HKD2_k127_7883992_7 Methyltransferase domain K06987 - - 0.00000000000000000000000000000000000000008853 160.0
HKD2_k127_7883992_8 ABC-2 type transporter K01992,K09692 - - 0.0000000000000000000000000000000000319 147.0
HKD2_k127_7883992_9 ABC transporter K01990,K09691,K09693 - 3.6.3.40 0.0000000000000000000000000000001193 141.0
HKD2_k127_7893833_0 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 - 2.3.2.3 0.00000000000000000000000000000000001115 156.0
HKD2_k127_7893833_1 esterase - - - 0.0000000000000000000000001004 116.0
HKD2_k127_7893833_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000007394 106.0
HKD2_k127_7893833_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000009878 69.0
HKD2_k127_7902803_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 318.0
HKD2_k127_7902803_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000001961 205.0
HKD2_k127_7902803_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000008124 85.0
HKD2_k127_7902803_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000004641 69.0
HKD2_k127_7907580_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1177.0
HKD2_k127_7907580_1 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001863 275.0
HKD2_k127_7907580_2 nadp oxidoreductase, coenzyme f420-dependent - - - 0.00000000000000000000000000000000000000005806 166.0
HKD2_k127_7913189_0 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 414.0
HKD2_k127_7913189_1 ABC 3 transport family K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003153 267.0
HKD2_k127_7913189_2 ATPases associated with a variety of cellular activities K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004022 259.0
HKD2_k127_7913189_3 Belongs to the bacterial solute-binding protein 9 family K09818 - - 0.0000000000000000000000000000000000000000000000000000000006537 215.0
HKD2_k127_7913189_4 Thioredoxin - - - 0.0000000000000000000000000000000000007868 153.0
HKD2_k127_7913189_5 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000157 127.0
HKD2_k127_7913189_6 quinone binding - - - 0.000000000000001333 86.0
HKD2_k127_7929654_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1151.0
HKD2_k127_7929654_1 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 338.0
HKD2_k127_7929654_2 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 332.0
HKD2_k127_7929654_3 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000006022 271.0
HKD2_k127_7929654_4 Glycogen debranching enzyme - - - 0.0000000005201 73.0
HKD2_k127_7929654_5 Glycosyltransferase family 87 - - - 0.00003974 55.0
HKD2_k127_7931441_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000001399 236.0
HKD2_k127_7931441_1 Superoxide dismutase K00518 - 1.15.1.1 0.00000000000000000000000000002323 126.0
HKD2_k127_7931441_2 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.000000003772 68.0
HKD2_k127_7931441_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000001632 63.0
HKD2_k127_7932826_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 2.07e-202 644.0
HKD2_k127_7932826_1 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 473.0
HKD2_k127_7932826_10 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) K02351,K07245 - - 0.0000000000000000000000000000000000000000000000001492 190.0
HKD2_k127_7932826_11 PFAM cytochrome c oxidase subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000018 161.0
HKD2_k127_7932826_12 Cytochrome c oxidase subunit K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000003828 160.0
HKD2_k127_7932826_13 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000000000000000000000000001659 124.0
HKD2_k127_7932826_14 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000001979 131.0
HKD2_k127_7932826_15 Sugar (and other) transporter - - - 0.0000000000000000000000002622 120.0
HKD2_k127_7932826_16 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000001485 117.0
HKD2_k127_7932826_17 Transcriptional regulator, TraR DksA family K06204 - - 0.0000000000001637 74.0
HKD2_k127_7932826_18 PFAM blue (type 1) copper domain protein - - - 0.000000000008747 77.0
HKD2_k127_7932826_19 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.00000001794 65.0
HKD2_k127_7932826_2 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009581 467.0
HKD2_k127_7932826_20 diguanylate cyclase - - - 0.00000121 61.0
HKD2_k127_7932826_21 LysM domain - - - 0.0004234 51.0
HKD2_k127_7932826_3 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 438.0
HKD2_k127_7932826_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 342.0
HKD2_k127_7932826_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 322.0
HKD2_k127_7932826_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 318.0
HKD2_k127_7932826_7 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000535 297.0
HKD2_k127_7932826_8 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001023 267.0
HKD2_k127_7932826_9 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000198 215.0
HKD2_k127_7944796_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003321 263.0
HKD2_k127_7950974_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 312.0
HKD2_k127_7950974_1 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 280.0
HKD2_k127_7950974_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000007958 252.0
HKD2_k127_7950974_3 YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000000000000000000000000000205 174.0
HKD2_k127_7950974_4 Response regulator receiver - - - 0.0000000000000000000000000000001188 139.0
HKD2_k127_7950974_5 Response regulator receiver K07696 - - 0.00000000000000000000000000000322 131.0
HKD2_k127_7950974_7 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000007934 84.0
HKD2_k127_7950974_8 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000429 53.0
HKD2_k127_7962269_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.324e-268 874.0
HKD2_k127_7962269_1 Heat shock 70 kDa protein K04043 - - 2.821e-252 806.0
HKD2_k127_7962269_10 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001348 259.0
HKD2_k127_7962269_11 Carboxylesterase family K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000001615 247.0
HKD2_k127_7962269_12 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000408 233.0
HKD2_k127_7962269_13 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000001386 230.0
HKD2_k127_7962269_14 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000004123 174.0
HKD2_k127_7962269_15 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000004011 151.0
HKD2_k127_7962269_16 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000002613 146.0
HKD2_k127_7962269_17 GatB Yqey domain protein K09117 - - 0.00000000000000000000000000000001065 136.0
HKD2_k127_7962269_18 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000154 141.0
HKD2_k127_7962269_19 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000003436 119.0
HKD2_k127_7962269_2 ABC transporter K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 439.0
HKD2_k127_7962269_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000005577 102.0
HKD2_k127_7962269_21 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000005618 82.0
HKD2_k127_7962269_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 404.0
HKD2_k127_7962269_4 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 398.0
HKD2_k127_7962269_5 Transport permease protein K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 327.0
HKD2_k127_7962269_6 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 326.0
HKD2_k127_7962269_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 304.0
HKD2_k127_7962269_8 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009994 285.0
HKD2_k127_7962269_9 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004646 268.0
HKD2_k127_7962514_0 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 565.0
HKD2_k127_7962514_1 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 339.0
HKD2_k127_7962514_2 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000001072 198.0
HKD2_k127_7962514_3 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000005268 71.0
HKD2_k127_7963800_0 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000003663 217.0
HKD2_k127_7963800_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000001342 170.0
HKD2_k127_7963800_2 Major facilitator Superfamily - - - 0.0000000000000000000000000000000006016 134.0
HKD2_k127_7980_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 437.0
HKD2_k127_7980_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 397.0
HKD2_k127_7980_2 Exporter of polyketide antibiotics K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 383.0
HKD2_k127_7980_3 DinB family - - - 0.00000000000000000000000000000000000198 145.0
HKD2_k127_7980_4 Rossmann-like domain K06988 - 1.5.1.40 0.000000000000000000000000000000000003687 144.0
HKD2_k127_7980_5 Chromate resistance exported protein - - - 0.0000000000000000000000000000001159 131.0
HKD2_k127_7980_6 NlpC/P60 family K21471 - - 0.00000000000001915 82.0
HKD2_k127_7980917_0 Belongs to the GcvT family - - - 0.0 1125.0
HKD2_k127_7980917_1 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.069e-194 620.0
HKD2_k127_7980917_10 Cobalt transport protein K02008,K16785 - - 0.000000000000000000000000000000000004774 147.0
HKD2_k127_7980917_11 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.00000000000000000000000192 114.0
HKD2_k127_7980917_12 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.000000000000002489 79.0
HKD2_k127_7980917_2 nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 357.0
HKD2_k127_7980917_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 319.0
HKD2_k127_7980917_4 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
HKD2_k127_7980917_5 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000002481 243.0
HKD2_k127_7980917_6 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000007728 235.0
HKD2_k127_7980917_7 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000672 211.0
HKD2_k127_7980917_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000001047 214.0
HKD2_k127_7980917_9 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000000000000000000000000000004121 165.0
HKD2_k127_7981194_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 303.0
HKD2_k127_7981194_1 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
HKD2_k127_7997162_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 428.0
HKD2_k127_7997162_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008785 264.0
HKD2_k127_7997162_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000302 185.0
HKD2_k127_7997162_3 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000003965 174.0
HKD2_k127_7997162_4 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000003627 138.0
HKD2_k127_7997162_5 PFAM zinc finger, SWIM domain protein - - - 0.0000000000000000000000003884 108.0
HKD2_k127_7997162_6 ABC transporter K02013 - 3.6.3.34 0.000000000000000001606 101.0
HKD2_k127_8007344_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 483.0
HKD2_k127_8007344_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 381.0
HKD2_k127_8007344_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009296 363.0
HKD2_k127_8007344_3 CBS domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000272 302.0
HKD2_k127_8007344_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000108 262.0
HKD2_k127_8007344_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000032 214.0
HKD2_k127_8007344_6 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000008527 172.0
HKD2_k127_8007344_7 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000003356 155.0
HKD2_k127_8007344_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000003238 154.0
HKD2_k127_8007344_9 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000009169 56.0
HKD2_k127_8011307_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000006455 220.0
HKD2_k127_8011307_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000001834 207.0
HKD2_k127_8011307_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000347 137.0
HKD2_k127_8011307_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000008915 130.0
HKD2_k127_8015829_0 Domain of unknown function (DUF4445) - - - 4.168e-277 871.0
HKD2_k127_8015829_1 Trimethylamine methyltransferase (MTTB) - - - 3.652e-235 749.0
HKD2_k127_8015829_10 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 350.0
HKD2_k127_8015829_11 cystathionine beta-lyase K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 344.0
HKD2_k127_8015829_12 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 331.0
HKD2_k127_8015829_13 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 286.0
HKD2_k127_8015829_14 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000006763 261.0
HKD2_k127_8015829_15 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001792 228.0
HKD2_k127_8015829_16 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000000001692 219.0
HKD2_k127_8015829_17 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000005227 205.0
HKD2_k127_8015829_18 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.000000000000000000000000000000000000000000000000003109 201.0
HKD2_k127_8015829_19 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000000466 183.0
HKD2_k127_8015829_2 Phosphoesterase family - - - 7.458e-219 695.0
HKD2_k127_8015829_20 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000008462 168.0
HKD2_k127_8015829_21 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000932 173.0
HKD2_k127_8015829_22 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000004531 163.0
HKD2_k127_8015829_23 cell redox homeostasis K02199 - - 0.000000000000000000000000000000000000000458 162.0
HKD2_k127_8015829_24 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000002582 152.0
HKD2_k127_8015829_25 Virulence factor - - - 0.0000000000000000000008753 107.0
HKD2_k127_8015829_26 protein required for cytochrome oxidase assembly K02259 - - 0.000000000000000001109 90.0
HKD2_k127_8015829_27 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000218 100.0
HKD2_k127_8015829_28 cyclic nucleotide binding K09766,K10914 - - 0.000000000000000006331 98.0
HKD2_k127_8015829_29 cGMP-dependent protein kinase activity K07376,K19477 - 2.7.11.12 0.000000000000157 82.0
HKD2_k127_8015829_3 Binding-protein-dependent transport system inner membrane component K02001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 601.0
HKD2_k127_8015829_30 Hydrolase Family 16 - - - 0.0000003706 56.0
HKD2_k127_8015829_31 FCD domain - - - 0.0007044 46.0
HKD2_k127_8015829_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 526.0
HKD2_k127_8015829_5 ATPases associated with a variety of cellular activities K02000 - 3.6.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 491.0
HKD2_k127_8015829_6 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 432.0
HKD2_k127_8015829_7 glycine betaine transport K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 385.0
HKD2_k127_8015829_8 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 371.0
HKD2_k127_8015829_9 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 376.0
HKD2_k127_8018994_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 451.0
HKD2_k127_8018994_1 belongs to the sigma-70 factor family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 458.0
HKD2_k127_8018994_10 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000002762 163.0
HKD2_k127_8018994_11 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000001382 153.0
HKD2_k127_8018994_12 YCII-related domain - - - 0.000000000000000000000000000000001634 138.0
HKD2_k127_8018994_13 - - - - 0.000000002589 62.0
HKD2_k127_8018994_14 - - - - 0.00004861 51.0
HKD2_k127_8018994_2 ggdef domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 439.0
HKD2_k127_8018994_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 450.0
HKD2_k127_8018994_4 DNA primase, small subunit K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 408.0
HKD2_k127_8018994_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 339.0
HKD2_k127_8018994_6 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009774 290.0
HKD2_k127_8018994_7 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001633 252.0
HKD2_k127_8018994_8 Bacterial signalling protein N terminal repeat - - - 0.000000000000000000000000000000000000000000000000000000002057 223.0
HKD2_k127_8018994_9 membrane protein of uknown function UCP014873 - - - 0.00000000000000000000000000000000000000000000000000000001143 206.0
HKD2_k127_8019731_0 - - - - 0.000000000000000000007775 107.0
HKD2_k127_8026628_0 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 464.0
HKD2_k127_8026628_1 Histidine kinase-like ATPases K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 403.0
HKD2_k127_8026628_2 oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 351.0
HKD2_k127_8026628_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 302.0
HKD2_k127_8026628_4 PFAM Peptidase family M23 - - - 0.0000000000000828 81.0
HKD2_k127_8026628_5 EamA-like transporter family - - - 0.0000002456 62.0
HKD2_k127_8057572_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 457.0
HKD2_k127_8057572_1 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000007091 267.0
HKD2_k127_8057572_2 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000000001276 190.0
HKD2_k127_8057572_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000005087 145.0
HKD2_k127_8057572_4 Polyketide cyclase dehydrase - - - 0.0000000000000000000000003317 115.0
HKD2_k127_8057572_5 Major facilitator Superfamily - - - 0.000000002118 61.0
HKD2_k127_8057572_6 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.00000002749 66.0
HKD2_k127_80580_0 - - - - 1.585e-235 760.0
HKD2_k127_80580_1 FGGY family of carbohydrate kinases, N-terminal domain - - - 3.883e-201 657.0
HKD2_k127_80580_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001901 151.0
HKD2_k127_80580_11 Pfam:Pyridox_oxidase - - - 0.000000000000000000000284 111.0
HKD2_k127_80580_12 AroM protein - - - 0.00000000000000001283 92.0
HKD2_k127_80580_13 Zincin-like metallopeptidase - - - 0.000000000000004139 81.0
HKD2_k127_80580_2 FAD linked oxidases, C-terminal domain K00102,K00803 - 1.1.2.4,2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 603.0
HKD2_k127_80580_3 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 549.0
HKD2_k127_80580_4 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 367.0
HKD2_k127_80580_5 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 349.0
HKD2_k127_80580_6 PFAM Phosphatidylinositol 3- and 4-kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 292.0
HKD2_k127_80580_7 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008498 267.0
HKD2_k127_80580_8 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001038 246.0
HKD2_k127_80580_9 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000005613 201.0
HKD2_k127_8068023_0 Glycosyl Transferase - - - 3.116e-250 798.0
HKD2_k127_8068023_1 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 355.0
HKD2_k127_8068023_2 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 347.0
HKD2_k127_8068023_3 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004584 272.0
HKD2_k127_8068023_4 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002674 244.0
HKD2_k127_8068023_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000146 201.0
HKD2_k127_8068023_6 Putative lumazine-binding - - - 0.000000000000000008437 90.0
HKD2_k127_8091923_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 444.0
HKD2_k127_8091923_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 344.0
HKD2_k127_8091923_2 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000004419 209.0
HKD2_k127_8091923_3 - - - - 0.00004589 53.0
HKD2_k127_8098463_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 384.0
HKD2_k127_8098463_1 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001334 251.0
HKD2_k127_8098463_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000004545 189.0
HKD2_k127_8098463_3 Binds the 23S rRNA K02909 - - 0.0000000000000000000000165 103.0
HKD2_k127_8098463_4 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000008888 100.0
HKD2_k127_8098463_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000008726 57.0
HKD2_k127_8104006_0 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 434.0
HKD2_k127_8111744_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 441.0
HKD2_k127_8111744_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 387.0
HKD2_k127_8111744_10 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000001786 203.0
HKD2_k127_8111744_11 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000009428 164.0
HKD2_k127_8111744_12 Stage II sporulation protein K06381 - - 0.000000000000000000000000000004597 128.0
HKD2_k127_8111744_13 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000000000005821 137.0
HKD2_k127_8111744_14 LysE type translocator - - - 0.00000000000000000000000000004115 134.0
HKD2_k127_8111744_15 membrane - - - 0.00000001357 65.0
HKD2_k127_8111744_16 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000005413 55.0
HKD2_k127_8111744_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 379.0
HKD2_k127_8111744_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 361.0
HKD2_k127_8111744_4 ABC transporter K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 361.0
HKD2_k127_8111744_5 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 332.0
HKD2_k127_8111744_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 304.0
HKD2_k127_8111744_7 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005186 286.0
HKD2_k127_8111744_8 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000009624 233.0
HKD2_k127_8111744_9 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000003829 208.0
HKD2_k127_8117559_0 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 513.0
HKD2_k127_8117559_1 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 314.0
HKD2_k127_8117559_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004126 256.0
HKD2_k127_8117559_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000007464 232.0
HKD2_k127_8117559_4 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000002775 162.0
HKD2_k127_8149542_0 Alpha amylase, catalytic domain - - - 0.0 1195.0
HKD2_k127_8149542_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 346.0
HKD2_k127_8149542_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000006514 205.0
HKD2_k127_8149542_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000001018 105.0
HKD2_k127_8149542_4 TPM domain K06872 - - 0.000000008617 68.0
HKD2_k127_8149542_5 Ami_2 K01447,K11062 - 3.5.1.28 0.0000000211 61.0
HKD2_k127_8149542_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00004375 56.0
HKD2_k127_820187_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 557.0
HKD2_k127_820187_1 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 239.0
HKD2_k127_8224920_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 339.0
HKD2_k127_8224920_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000004068 121.0
HKD2_k127_822853_0 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 447.0
HKD2_k127_822853_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001585 265.0
HKD2_k127_822853_2 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000001226 161.0
HKD2_k127_822853_3 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000001789 162.0
HKD2_k127_822853_4 Rhodanese-related sulfurtransferase - - - 0.00000000000000000001051 100.0
HKD2_k127_8298444_0 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 319.0
HKD2_k127_8298444_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002097 280.0
HKD2_k127_8298444_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000009147 124.0
HKD2_k127_8298444_3 extracellular polysaccharide biosynthetic process K09690,K16554,K16692 - - 0.0000002806 58.0
HKD2_k127_8400147_0 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 481.0
HKD2_k127_8400147_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 441.0
HKD2_k127_8400147_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000008991 129.0
HKD2_k127_8461697_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03336 - 3.7.1.22 6.233e-275 861.0
HKD2_k127_8461697_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 437.0
HKD2_k127_8461697_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 401.0
HKD2_k127_8461697_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 391.0
HKD2_k127_8461697_4 COGs COG0673 dehydrogenase and related protein K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 367.0
HKD2_k127_8461697_5 Inosose dehydratase K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 382.0
HKD2_k127_8461697_6 Belongs to the peptidase S8 family K12287 - - 0.0000003982 61.0
HKD2_k127_8461697_7 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.0000008127 61.0
HKD2_k127_8461697_8 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K01537,K12952 - 3.6.3.2,3.6.3.8 0.00005608 56.0
HKD2_k127_8463658_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 398.0
HKD2_k127_8463658_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001922 258.0
HKD2_k127_8463658_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.000000000000000000000000000000000000000000000000000000000000000000000007717 248.0
HKD2_k127_8463658_3 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000001388 216.0
HKD2_k127_8463658_4 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000007351 169.0
HKD2_k127_8463658_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000004513 104.0
HKD2_k127_8463658_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000005406 57.0
HKD2_k127_8526298_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0 1722.0
HKD2_k127_8526298_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 590.0
HKD2_k127_8526298_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 346.0
HKD2_k127_8526298_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000327 233.0
HKD2_k127_8526298_4 Belongs to the 5'-nucleotidase family K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000000000000000000000000000000000000000000000002844 217.0
HKD2_k127_8526298_5 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000002258 90.0
HKD2_k127_8532630_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 473.0
HKD2_k127_8532630_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
HKD2_k127_8532630_2 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000067 227.0
HKD2_k127_8532630_3 Belongs to the RNA methyltransferase TrmD family K00554,K01770 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228,4.6.1.12 0.000000000000000000000000000000000005771 140.0
HKD2_k127_8532630_4 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000172 120.0
HKD2_k127_8532630_5 Belongs to the UPF0109 family K06960 - - 0.000000000000000000004449 94.0
HKD2_k127_8532630_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000296 94.0
HKD2_k127_8532630_7 Protein of unknown function (DUF3352) - - - 0.0000000000000003589 93.0
HKD2_k127_8645411_0 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K02029 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 338.0
HKD2_k127_8645411_1 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 298.0
HKD2_k127_8645411_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005558 297.0
HKD2_k127_8645411_3 Bacterial periplasmic substrate-binding proteins K02030,K02424,K17073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003556 276.0
HKD2_k127_8645411_4 WYL domain K07012,K13572 - - 0.0000000000000000000000000000000000000000000000000000000007642 226.0
HKD2_k127_8645411_5 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000008081 160.0
HKD2_k127_8645411_6 diguanylate cyclase - - - 0.00000000000000000000000000000000000002221 167.0
HKD2_k127_8645411_7 peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000006779 136.0
HKD2_k127_8645411_8 Peptidoglycan-binding LysM K08259 - 3.4.24.75 0.000000000795 71.0
HKD2_k127_8645411_9 Peptidase family M23 - - - 0.0001427 48.0
HKD2_k127_885490_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 537.0
HKD2_k127_885490_1 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000002644 237.0
HKD2_k127_885490_2 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000003224 154.0
HKD2_k127_885490_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000002104 104.0
HKD2_k127_885490_4 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000001062 57.0
HKD2_k127_8949129_0 ABC transporter K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 362.0
HKD2_k127_8949129_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001403 250.0
HKD2_k127_8949129_2 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000005293 203.0
HKD2_k127_8949129_3 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000003045 201.0
HKD2_k127_8949129_4 Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000000000004633 196.0
HKD2_k127_8949129_5 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000002601 167.0
HKD2_k127_8949129_6 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000001725 124.0
HKD2_k127_8949129_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000005211 107.0
HKD2_k127_8955509_0 Belongs to the glycosyl hydrolase 13 family - - - 2.507e-279 905.0
HKD2_k127_8955509_1 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 513.0
HKD2_k127_8955509_10 Beta-lactamase superfamily domain - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000000000000000000002285 151.0
HKD2_k127_8955509_11 TIGRFAM histidinol phosphate phosphatase HisJ K04486 - 3.1.3.15 0.000000000000000000000000000000005122 148.0
HKD2_k127_8955509_12 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000001447 134.0
HKD2_k127_8955509_13 Protein of unknown function (DUF3105) - - - 0.0000000000000000009234 97.0
HKD2_k127_8955509_14 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000001021 87.0
HKD2_k127_8955509_15 - - - - 0.000000000000003487 87.0
HKD2_k127_8955509_16 ubiE/COQ5 methyltransferase family - - - 0.0000002148 63.0
HKD2_k127_8955509_2 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 516.0
HKD2_k127_8955509_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 485.0
HKD2_k127_8955509_4 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 364.0
HKD2_k127_8955509_5 PFAM Bacterial extracellular solute-binding protein K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 364.0
HKD2_k127_8955509_6 PFAM Binding-protein-dependent transport system inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 334.0
HKD2_k127_8955509_7 periplasmic binding protein LacI transcriptional regulator K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005015 281.0
HKD2_k127_8955509_8 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16164 - 3.7.1.5 0.0000000000000000000000000000000000000000000000000000000000024 220.0
HKD2_k127_8955509_9 spore germination - - - 0.0000000000000000000000000000000000000000000000007065 189.0
HKD2_k127_8962678_0 Biotin carboxylase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 305.0
HKD2_k127_8962678_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 294.0
HKD2_k127_8991649_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 592.0
HKD2_k127_8991649_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 349.0
HKD2_k127_8991649_2 response to abiotic stimulus - - - 0.000000000000000000000000000000000000000001101 164.0
HKD2_k127_8995942_0 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 348.0
HKD2_k127_8995942_1 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 304.0
HKD2_k127_8995942_10 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.000000000000000000000003309 115.0
HKD2_k127_8995942_11 - - - - 0.0000000000000000000001291 107.0
HKD2_k127_8995942_12 - - - - 0.000000000000000001937 89.0
HKD2_k127_8995942_13 - - - - 0.0000000001215 68.0
HKD2_k127_8995942_14 diguanylate cyclase - - - 0.00000001012 66.0
HKD2_k127_8995942_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006824 251.0
HKD2_k127_8995942_3 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000003973 205.0
HKD2_k127_8995942_4 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000173 175.0
HKD2_k127_8995942_5 methyltransferase K16129 - - 0.000000000000000000000000000000000004145 147.0
HKD2_k127_8995942_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000388 127.0
HKD2_k127_8995942_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000006342 124.0
HKD2_k127_8995942_8 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000001158 116.0
HKD2_k127_8995942_9 cheY-homologous receiver domain K11443 - - 0.000000000000000000000001104 120.0
HKD2_k127_8996659_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 517.0
HKD2_k127_8996659_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 414.0
HKD2_k127_8996810_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 402.0
HKD2_k127_8996810_1 - - - - 0.00000000000003973 78.0
HKD2_k127_8996810_2 SnoaL-like polyketide cyclase K06893 - - 0.00001535 53.0
HKD2_k127_8996810_3 Carbon-nitrogen hydrolase - - - 0.00006445 51.0
HKD2_k127_9027537_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1080.0
HKD2_k127_9027537_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 513.0
HKD2_k127_9027537_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000006996 244.0
HKD2_k127_9027537_3 NUDIX domain - - - 0.000000000000000000000004801 110.0
HKD2_k127_9046130_0 transferase activity, transferring hexosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 341.0
HKD2_k127_9046130_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000001215 204.0
HKD2_k127_9046901_0 COG0608 Single-stranded DNA-specific exonuclease K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 298.0
HKD2_k127_9046901_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000001944 98.0
HKD2_k127_9046901_2 Dipeptidyl peptidase IV (DPP IV) N-terminal region K03641 - - 0.00000000000000001035 96.0
HKD2_k127_9066819_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 301.0
HKD2_k127_9066819_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000006489 192.0
HKD2_k127_9066819_2 Glyoxalase-like domain K08234 - - 0.00000000001343 72.0
HKD2_k127_9066819_3 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0005555 44.0
HKD2_k127_9077382_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 546.0
HKD2_k127_9077382_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 348.0
HKD2_k127_9077382_2 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 292.0
HKD2_k127_9077382_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000008763 192.0
HKD2_k127_9095425_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001514 284.0
HKD2_k127_9095425_1 heat shock protein K04762 - - 0.0000000000000000000000000000001605 130.0
HKD2_k127_9097557_0 Participates in initiation and elongation during chromosome replication K02314 GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 488.0
HKD2_k127_9097557_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000001922 181.0
HKD2_k127_9097557_2 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000006311 132.0
HKD2_k127_9097557_3 Probable zinc-ribbon domain - - - 0.0000000000000000000000000002213 132.0
HKD2_k127_9097557_4 phosphatidylinositol metabolic process - - - 0.00000000307 69.0
HKD2_k127_9097557_5 Protein of unknown function (DUF1232) - - - 0.0001408 52.0
HKD2_k127_9129_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01873 - 6.1.1.9 5.567e-236 759.0
HKD2_k127_9129_1 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 430.0
HKD2_k127_9129_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000008441 229.0
HKD2_k127_9129_3 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000008773 189.0
HKD2_k127_9129_4 Putative regulatory protein - - - 0.0000000214 60.0
HKD2_k127_9129_5 lipopolysaccharide transmembrane transporter activity K07058 - - 0.000001141 60.0
HKD2_k127_9133634_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000003719 169.0
HKD2_k127_9145456_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 503.0
HKD2_k127_9145456_1 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 295.0
HKD2_k127_9149344_0 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 590.0
HKD2_k127_9149344_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005491 262.0
HKD2_k127_9149344_2 Cobalamin B12-binding K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000004824 195.0
HKD2_k127_9149344_3 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000007234 134.0
HKD2_k127_9153983_0 catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation K17723 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 522.0
HKD2_k127_9153983_1 Acetamidase formamidase K01455 - 3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 364.0
HKD2_k127_9153983_2 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000003145 235.0
HKD2_k127_9153983_3 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000003671 163.0
HKD2_k127_9153983_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000002591 160.0
HKD2_k127_9153983_5 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000001205 150.0
HKD2_k127_9153983_6 DNA-binding protein - - - 0.0000000000000000000000000004775 121.0
HKD2_k127_9158295_0 Dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 554.0
HKD2_k127_9158295_1 Uncharacterised protein family (UPF0261) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 488.0
HKD2_k127_9158295_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 465.0
HKD2_k127_9158295_3 Dak1 domain K00863,K05878,K05879 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 407.0
HKD2_k127_9158295_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 351.0
HKD2_k127_9158295_5 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 329.0
HKD2_k127_9158295_6 PFAM regulatory protein GntR HTH K22293 - - 0.00000000000000000000000000000000000000000000000000000000000000000000362 254.0
HKD2_k127_9158295_7 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000467 108.0
HKD2_k127_9158295_8 Cupin 2, conserved barrel domain protein K00450,K01628 - 1.13.11.4,4.1.2.17 0.00000008941 58.0
HKD2_k127_9187786_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 535.0
HKD2_k127_9187786_1 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 393.0
HKD2_k127_9187786_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 322.0
HKD2_k127_9187786_3 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 316.0
HKD2_k127_9187786_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 313.0
HKD2_k127_9187786_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000004362 163.0
HKD2_k127_9187786_6 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000008422 131.0
HKD2_k127_9187786_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000001425 133.0
HKD2_k127_9187786_8 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.000000000000000000000000001107 124.0
HKD2_k127_9187786_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.00000005759 63.0
HKD2_k127_9188374_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 406.0
HKD2_k127_9188374_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 334.0
HKD2_k127_9188374_2 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000002437 236.0
HKD2_k127_9188374_3 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000005401 237.0
HKD2_k127_9188374_4 diacylglycerol kinase - - - 0.00000000000000000000000000001364 136.0
HKD2_k127_9201794_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 351.0
HKD2_k127_9208532_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 422.0
HKD2_k127_9208532_1 LURP-one-related - - - 0.0000000000000000000000000000000000000000000000000000000002277 207.0
HKD2_k127_9208532_2 Short C-terminal domain - - - 0.0000000000000003119 87.0
HKD2_k127_9208532_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine - - - 0.00000000003807 70.0
HKD2_k127_9213086_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 462.0
HKD2_k127_9213086_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 309.0
HKD2_k127_9213086_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008307 272.0
HKD2_k127_9239739_0 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 480.0
HKD2_k127_9239739_1 Major facilitator superfamily - - - 0.00000000000006286 85.0
HKD2_k127_9314805_0 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000002402 119.0
HKD2_k127_9315671_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009773 302.0
HKD2_k127_9315671_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000001075 90.0
HKD2_k127_9427348_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 8.434e-258 814.0
HKD2_k127_9427348_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 440.0
HKD2_k127_9427348_2 tRNA binding K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 437.0
HKD2_k127_9427348_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000005955 235.0
HKD2_k127_9427348_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000001899 230.0
HKD2_k127_9427348_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000004532 167.0
HKD2_k127_9427348_6 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000001341 159.0
HKD2_k127_9427348_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000842 156.0
HKD2_k127_9427348_8 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000004068 121.0
HKD2_k127_9432405_0 domain protein - - - 0.0001084 54.0
HKD2_k127_9455440_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 430.0
HKD2_k127_9455440_1 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 373.0
HKD2_k127_9455440_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000438 243.0
HKD2_k127_9455440_3 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.00000000000000000000000000000000000000000000000001179 183.0
HKD2_k127_9455440_4 Pfam:DUF385 - - - 0.0000000000000000000000000000000000000002966 161.0
HKD2_k127_9455440_5 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000002035 125.0
HKD2_k127_9484212_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 492.0
HKD2_k127_9484212_1 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000001148 108.0
HKD2_k127_9484268_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 6.34e-197 646.0
HKD2_k127_9484268_1 - - - - 0.0003273 52.0
HKD2_k127_9484949_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 301.0
HKD2_k127_9484949_1 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000001108 141.0
HKD2_k127_9484949_2 PFAM OsmC family protein K07397 - - 0.00000000000000000000000002848 119.0
HKD2_k127_9484949_3 Cytochrome C biogenesis protein - - - 0.0000000000000000000000003793 111.0
HKD2_k127_9484949_4 Transcriptional regulator, arsR family - - - 0.00000000000000000000003683 103.0
HKD2_k127_9484949_5 Rhodanese Homology Domain - - - 0.0000000000000000000003073 107.0
HKD2_k127_9484949_7 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000008131 77.0
HKD2_k127_9484949_8 Protein of unknown function (DUF1634) - - - 0.0000004049 60.0
HKD2_k127_9485515_0 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 392.0
HKD2_k127_9485515_1 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000006553 172.0
HKD2_k127_9485515_2 -acetyltransferase - - - 0.00000000000000000000000000000001885 144.0
HKD2_k127_9485515_3 YwiC-like protein - - - 0.00000000000000000000008527 108.0
HKD2_k127_9485515_4 - - - - 0.0000000000000000004173 92.0
HKD2_k127_9485515_5 - - - - 0.000000000001109 73.0
HKD2_k127_9485515_6 pfkB family carbohydrate kinase - - - 0.0000000001686 70.0
HKD2_k127_9513992_0 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 443.0
HKD2_k127_9513992_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 390.0
HKD2_k127_9513992_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000137 194.0
HKD2_k127_9536830_0 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 509.0
HKD2_k127_9536830_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 375.0
HKD2_k127_9536830_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000001485 221.0
HKD2_k127_9645641_0 Putative zinc-finger - - - 0.0000000000000000000000000000000000000000000000000000000001587 213.0
HKD2_k127_9645641_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000003317 188.0
HKD2_k127_9645641_2 Protein of unknown function (DUF2892) - - - 0.000000007603 59.0
HKD2_k127_9664148_0 response to copper ion - - - 0.00000000000000000000000000000000000000000006079 173.0
HKD2_k127_9664148_1 domain, Protein - - - 0.0000000000000000000000000000000005097 145.0
HKD2_k127_999813_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.3 1.372e-217 691.0
HKD2_k127_999813_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 494.0
HKD2_k127_999813_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003219 276.0
HKD2_k127_999813_3 PFAM Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000008065 136.0