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Overview

ID MAG01809
Name HKD2_bin.62
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family RBG-16-64-43
Genus JAFGKK01
Species
Assembly information
Completeness (%) 73.73
Contamination (%) 3.45
GC content (%) 63.0
N50 (bp) 2,983
Genome size (bp) 2,868,894

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2663

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_10000029_0 Putative zincin peptidase - - - 0.000000008648 64.0
HKD2_k127_10000029_1 sh3 domain protein K01448,K04771,K08884 - 2.7.11.1,3.4.21.107,3.5.1.28 0.0002834 53.0
HKD2_k127_10001597_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 362.0
HKD2_k127_10001597_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007923 274.0
HKD2_k127_10001597_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000003432 192.0
HKD2_k127_10001597_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000001373 129.0
HKD2_k127_10004111_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 510.0
HKD2_k127_10004111_1 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000001109 79.0
HKD2_k127_10013319_0 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 510.0
HKD2_k127_10014475_0 MBOAT, membrane-bound O-acyltransferase family K03739,K19294 - - 0.00000000000000000000000000000000000000000000000000000000000002354 233.0
HKD2_k127_10014475_1 LysM domain - - - 0.00000000000000000000000000000000005429 139.0
HKD2_k127_10014475_2 sh3 domain protein K01448 - 3.5.1.28 0.0002928 52.0
HKD2_k127_10019161_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000002452 195.0
HKD2_k127_10019161_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000002931 167.0
HKD2_k127_10023107_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 295.0
HKD2_k127_10023107_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001923 278.0
HKD2_k127_10023107_2 Response regulator receiver - - - 0.00000000000000000000000000000000006566 138.0
HKD2_k127_10026880_0 efflux transmembrane transporter activity K02004,K09808 - - 0.00000000000000000001328 106.0
HKD2_k127_10028870_0 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 353.0
HKD2_k127_10028870_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000000000001922 222.0
HKD2_k127_10028870_2 RbsD / FucU transport protein family K06726 - 5.4.99.62 0.00000000000000000000000000000000000000000003008 166.0
HKD2_k127_10028870_3 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000000008544 167.0
HKD2_k127_10028870_4 Putative zinc-finger - - - 0.0000000000000000109 85.0
HKD2_k127_10030515_0 GGDEF domain' - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 323.0
HKD2_k127_1003324_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 454.0
HKD2_k127_1003324_1 Heat shock protein DnaJ domain protein K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 339.0
HKD2_k127_1003324_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
HKD2_k127_1003324_3 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000002315 192.0
HKD2_k127_10036664_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 396.0
HKD2_k127_10036664_2 WD40-like Beta Propeller (InterPro IPR011659), Six-bladed beta-propeller, TolB-like (InterPro IPR011042) - - - 0.0005712 47.0
HKD2_k127_10047806_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000002646 91.0
HKD2_k127_10057221_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 310.0
HKD2_k127_10057221_1 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001258 278.0
HKD2_k127_10057221_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000265 132.0
HKD2_k127_10057221_3 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.00000000000000000000000000356 113.0
HKD2_k127_10062093_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002668 275.0
HKD2_k127_10062093_1 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000006154 263.0
HKD2_k127_10062093_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000002541 207.0
HKD2_k127_10062093_3 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000007506 187.0
HKD2_k127_10062093_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000235 176.0
HKD2_k127_10062093_5 NERD domain protein - - - 0.0002546 52.0
HKD2_k127_10064848_0 ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002901 261.0
HKD2_k127_10064848_1 ABC transporter permease K01992 - - 0.000000000000000000000000000000000000000000000000000000000002497 219.0
HKD2_k127_10064848_2 trisaccharide binding - - - 0.00000000000000000006836 92.0
HKD2_k127_10066991_0 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000000004554 109.0
HKD2_k127_10066991_1 serine threonine protein kinase - - - 0.000000000002327 77.0
HKD2_k127_10075563_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000009384 128.0
HKD2_k127_10075563_1 negative regulation of transcription, DNA-templated - - - 0.00000000000000000001642 98.0
HKD2_k127_10075563_2 elongation factor Tu domain 2 protein K06207 - - 0.000000000000000001377 86.0
HKD2_k127_10075563_3 Protein of unknown function (DUF1706) - - - 0.0000000007098 67.0
HKD2_k127_10075563_4 - - - - 0.0000015 51.0
HKD2_k127_10079434_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 309.0
HKD2_k127_10079434_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000009962 198.0
HKD2_k127_10079963_0 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000001741 93.0
HKD2_k127_10079963_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000008615 57.0
HKD2_k127_10087806_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000002363 199.0
HKD2_k127_10087806_1 Ketopantoate reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000005917 183.0
HKD2_k127_10090786_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 430.0
HKD2_k127_10090786_1 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 412.0
HKD2_k127_10110799_0 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000001424 155.0
HKD2_k127_10110799_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000004717 168.0
HKD2_k127_10114110_0 COG0438 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000085 180.0
HKD2_k127_10114110_1 Glycosyl transferase 4-like - - - 0.0000000000000000000000002056 111.0
HKD2_k127_10114976_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004128 267.0
HKD2_k127_1012347_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1007.0
HKD2_k127_10135162_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000697 113.0
HKD2_k127_10137352_0 Glycosyl hydrolase family 115 - - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
HKD2_k127_10137352_1 - - - - 0.0000000000000000000000000000000000000000002553 170.0
HKD2_k127_10142160_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 516.0
HKD2_k127_10142160_1 GHMP kinase K05305 - 2.7.1.52 0.0000000000000000000000000000000000000000000000000000000006545 207.0
HKD2_k127_10145940_0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain K01596,K01610 GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771 4.1.1.32,4.1.1.49 5.294e-291 905.0
HKD2_k127_10145940_1 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 293.0
HKD2_k127_10145940_2 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 293.0
HKD2_k127_10151940_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 501.0
HKD2_k127_10151940_1 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000001162 214.0
HKD2_k127_10151940_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000113 186.0
HKD2_k127_10162488_0 NADPH quinone reductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000009718 211.0
HKD2_k127_10162921_0 Binding-protein-dependent transport system inner membrane component K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 471.0
HKD2_k127_10162921_1 TOBE domain K02062,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 330.0
HKD2_k127_10168816_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 372.0
HKD2_k127_10168816_1 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000005535 190.0
HKD2_k127_10178527_0 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000002488 132.0
HKD2_k127_10178527_1 - K06921 - - 0.00000000000000000006896 98.0
HKD2_k127_10185679_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 441.0
HKD2_k127_10185679_1 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003263 285.0
HKD2_k127_10185679_2 ABC transporter K01990,K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003447 298.0
HKD2_k127_10187638_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 515.0
HKD2_k127_10187638_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000001884 251.0
HKD2_k127_10197009_0 Monogalactosyldiacylglycerol synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 385.0
HKD2_k127_1021858_0 Ferritin-like - - - 0.00000000000000000000000000000000000000000000000008503 187.0
HKD2_k127_1021858_1 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000004653 81.0
HKD2_k127_1028573_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 9.746e-204 647.0
HKD2_k127_1028573_1 spore germination - - - 0.0000000000000000000000000000000000000000000000000001337 194.0
HKD2_k127_1032002_0 Domain of unknown function (DUF1963) - - - 0.000000000000000000000000000000000000000000000000000001348 203.0
HKD2_k127_1032002_1 Carboxylesterase family - - - 0.0000000000000000000000000000000004262 142.0
HKD2_k127_1037186_0 FGGY family of carbohydrate kinases, N-terminal domain K00848,K00851,K00854,K00879,K01813 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.12,2.7.1.17,2.7.1.5,2.7.1.51,5.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 495.0
HKD2_k127_1039399_0 hydrolase activity, hydrolyzing O-glycosyl compounds K00690 - 2.4.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 487.0
HKD2_k127_1041802_0 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 354.0
HKD2_k127_1051439_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000004458 102.0
HKD2_k127_1051439_1 Glycosyl transferase 4-like domain - - - 0.0003254 48.0
HKD2_k127_1059000_0 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 373.0
HKD2_k127_1070061_0 UvrD REP helicase K03657 - 3.6.4.12 2.872e-230 728.0
HKD2_k127_1070061_1 - - - - 0.0000000000000007711 79.0
HKD2_k127_1079900_0 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001828 281.0
HKD2_k127_1079900_1 GAF domain K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003744 276.0
HKD2_k127_1079900_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000001418 219.0
HKD2_k127_1079900_3 Two component transcriptional regulator, winged helix family K10697 - - 0.0000000000000000000000000000000000000000000001752 179.0
HKD2_k127_1094007_0 imidazoleglycerol-phosphate synthase activity K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
HKD2_k127_1094007_1 glutamine metabolic process K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
HKD2_k127_1096342_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 9.921e-207 664.0
HKD2_k127_1096885_0 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 607.0
HKD2_k127_1096885_1 LysM domain K03046,K03641,K08642 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006593 447.0
HKD2_k127_1096885_2 PFAM DegV family protein - - - 0.0000000000000000000000000000000001027 147.0
HKD2_k127_1096885_3 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000001322 116.0
HKD2_k127_1096885_4 ribosomal protein L28 K02902 - - 0.0000000000000003983 85.0
HKD2_k127_1114461_0 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 3.907e-238 746.0
HKD2_k127_1114461_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000003305 139.0
HKD2_k127_1133070_0 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000001112 78.0
HKD2_k127_1152538_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.902e-281 884.0
HKD2_k127_1152538_1 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000006376 115.0
HKD2_k127_1152538_2 Beta-lactamase superfamily domain - - - 0.000000000000000008912 95.0
HKD2_k127_1152538_3 mercury ion transmembrane transporter activity K07213 - - 0.0000000000001261 74.0
HKD2_k127_1158158_0 response to heat K03668,K09914 - - 0.0000000435 64.0
HKD2_k127_1171011_0 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003313 279.0
HKD2_k127_1171011_1 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.00000000000000000000000000000000000001694 158.0
HKD2_k127_1171011_2 Phospholipase_D-nuclease N-terminal - - - 0.000000000000004616 76.0
HKD2_k127_118591_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 314.0
HKD2_k127_118591_1 TIGRFAM small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 297.0
HKD2_k127_118591_2 4-vinyl reductase, 4VR K07013,K17763 - - 0.00000000000000000000000000007438 129.0
HKD2_k127_118591_3 Metalloenzyme superfamily - - - 0.00000000000001035 87.0
HKD2_k127_1188036_0 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 400.0
HKD2_k127_1188036_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000005505 225.0
HKD2_k127_1188036_2 RIP homotypic interaction motif - - - 0.00000000002106 71.0
HKD2_k127_1188897_0 PFAM regulator of chromosome condensation, RCC1 - - - 2.577e-214 684.0
HKD2_k127_1188897_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003196 279.0
HKD2_k127_1190866_0 Tfp pilus assembly protein FimV - - - 0.000007043 57.0
HKD2_k127_1200870_0 Pkd domain containing protein K12567 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000767 217.0
HKD2_k127_1207429_0 - - - - 0.00000000000001098 83.0
HKD2_k127_1214445_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 459.0
HKD2_k127_1214445_1 phosphatase activity K07025 - - 0.00000000000006766 78.0
HKD2_k127_1214445_2 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 0.0006473 51.0
HKD2_k127_1225548_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 554.0
HKD2_k127_1239993_0 Cyclic nucleotide-binding protein - - - 0.0000000000000000000000000000000000000003361 162.0
HKD2_k127_1244018_0 DEAD DEAH box helicase domain protein K06877 - - 4.628e-218 700.0
HKD2_k127_1260815_0 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000922 186.0
HKD2_k127_1260815_1 Lipase (class 3) - - - 0.00000000000000000000000000000003527 136.0
HKD2_k127_1261034_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 392.0
HKD2_k127_1261034_1 - - - - 0.000000000000000000000000000000000212 146.0
HKD2_k127_1266180_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1099.0
HKD2_k127_1266180_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 414.0
HKD2_k127_1266180_2 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000003053 164.0
HKD2_k127_1273453_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 587.0
HKD2_k127_1273453_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 452.0
HKD2_k127_1273453_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000003225 112.0
HKD2_k127_1273453_3 - - - - 0.0005155 46.0
HKD2_k127_12797_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 595.0
HKD2_k127_12797_1 PFAM Roadblock LC7 family protein K07131 - - 0.000000000000000000000000000000000000000000000003265 175.0
HKD2_k127_1281172_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 355.0
HKD2_k127_1281172_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004567 250.0
HKD2_k127_1281172_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
HKD2_k127_1286762_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000001512 176.0
HKD2_k127_1286762_1 F420H(2)-dependent quinone reductase - - - 0.00000000000000000000000000106 117.0
HKD2_k127_1286762_2 channel protein, hemolysin III family K11068 - - 0.0000000000000000000613 89.0
HKD2_k127_1290784_0 Carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 390.0
HKD2_k127_1290784_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000003921 229.0
HKD2_k127_1290784_2 - - - - 0.00000000000000000000000004541 124.0
HKD2_k127_1290784_3 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000008404 100.0
HKD2_k127_1291095_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.000000007482 63.0
HKD2_k127_1291095_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K01808,K07566,K20201 - 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.000002231 52.0
HKD2_k127_1293585_0 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000001487 139.0
HKD2_k127_1293585_1 - - - - 0.000000000000000000711 98.0
HKD2_k127_1299181_0 Amino acid permease - - - 0.0000000003739 70.0
HKD2_k127_130164_0 Protein of unknown function (DUF4230) - - - 0.000000000000000000000000000001921 131.0
HKD2_k127_130164_1 pathogenesis K01447,K21471 - 3.5.1.28 0.00000001713 66.0
HKD2_k127_13046_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 394.0
HKD2_k127_13046_1 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001232 243.0
HKD2_k127_1315907_0 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 600.0
HKD2_k127_1315907_1 Fumarate reductase flavoprotein C-term K00239,K00278 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0044085,GO:0044237,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363 1.3.5.1,1.3.5.4,1.4.3.16 0.0000000000000000000000000002979 132.0
HKD2_k127_1315907_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000000003042 115.0
HKD2_k127_1315907_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000485 111.0
HKD2_k127_1318283_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000001047 162.0
HKD2_k127_1363878_0 LysM domain K02020 - - 0.000000009533 64.0
HKD2_k127_1368224_0 Heparinase II/III N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 458.0
HKD2_k127_1368224_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000002485 167.0
HKD2_k127_1372848_0 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 429.0
HKD2_k127_1372848_1 Uncharacterized protein conserved in bacteria (DUF2255) - - - 0.0000000000000000000000000000000000000005048 153.0
HKD2_k127_13753_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 606.0
HKD2_k127_13753_1 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003651 290.0
HKD2_k127_13753_2 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000008332 226.0
HKD2_k127_13753_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000002069 188.0
HKD2_k127_13753_4 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000001138 178.0
HKD2_k127_13753_5 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000761 73.0
HKD2_k127_1376387_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01655 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 365.0
HKD2_k127_1376387_1 Catalyzes the transfer of the amino group of L-glutamate to LysW -aminoadipate 6-semialdehyde, generating LysW -gamma-L- lysine K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 291.0
HKD2_k127_1379762_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003991 272.0
HKD2_k127_1379762_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000008425 119.0
HKD2_k127_1379762_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000039 113.0
HKD2_k127_1379762_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000131 102.0
HKD2_k127_1395516_0 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 424.0
HKD2_k127_1395516_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000284 238.0
HKD2_k127_1395516_2 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000009351 165.0
HKD2_k127_1395516_3 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000004215 117.0
HKD2_k127_1395516_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000469 101.0
HKD2_k127_1406444_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.505e-198 631.0
HKD2_k127_142173_0 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 296.0
HKD2_k127_142173_1 Metallo-beta-lactamase superfamily K00784 - 3.1.26.11 0.00000000000000000000000000000005334 144.0
HKD2_k127_1428247_0 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 351.0
HKD2_k127_1428247_1 protein modification by small protein conjugation - - - 0.0000000000000000000000000000000000008452 152.0
HKD2_k127_1428247_2 PFAM Mov34 MPN PAD-1 family - - - 0.000000000000000000000001477 113.0
HKD2_k127_1428247_3 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000356 106.0
HKD2_k127_1428247_4 WXG100 protein secretion system (Wss), protein YukD - - - 0.00000000001858 68.0
HKD2_k127_1428247_5 Von Willebrand factor type A - - - 0.00008125 51.0
HKD2_k127_1428271_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000243 173.0
HKD2_k127_1428271_1 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.0000000000000000000000000000002377 127.0
HKD2_k127_1428604_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 304.0
HKD2_k127_1428604_1 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.00000000000000000000000000000000000000000001898 174.0
HKD2_k127_1430463_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 531.0
HKD2_k127_1430463_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001486 274.0
HKD2_k127_1430463_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000005762 200.0
HKD2_k127_1431697_0 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 354.0
HKD2_k127_1441538_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009032 240.0
HKD2_k127_1441538_1 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000000000000001362 224.0
HKD2_k127_1441538_2 Esterase K01070 - 3.1.2.12 0.00000000000001902 81.0
HKD2_k127_1441908_0 PFAM ABC transporter related K01990,K16907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
HKD2_k127_1441908_1 abc transporter atp-binding protein K01990 - - 0.00000000000000000002347 92.0
HKD2_k127_1454386_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.647e-197 627.0
HKD2_k127_1454386_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000001884 237.0
HKD2_k127_1454609_0 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 323.0
HKD2_k127_1454609_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000008754 125.0
HKD2_k127_1460225_0 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 569.0
HKD2_k127_1460225_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000001066 244.0
HKD2_k127_1460225_2 PFAM adenylate cyclase K05873 - 4.6.1.1 0.0000000000000000000000000000002026 133.0
HKD2_k127_1460225_3 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000000000000000001328 127.0
HKD2_k127_1460225_4 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000009879 94.0
HKD2_k127_1474053_0 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 344.0
HKD2_k127_1474053_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00651 - 2.3.1.46 0.000006727 48.0
HKD2_k127_1478663_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 488.0
HKD2_k127_1478663_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000001102 144.0
HKD2_k127_1495512_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000007002 79.0
HKD2_k127_1495512_1 PFAM Forkhead-associated protein - - - 0.0000001334 61.0
HKD2_k127_1496156_0 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 316.0
HKD2_k127_1496156_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000001284 160.0
HKD2_k127_1496156_2 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000005289 81.0
HKD2_k127_1509867_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1087.0
HKD2_k127_1522321_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000005521 220.0
HKD2_k127_1522321_1 diguanylate cyclase - - - 0.000000003271 71.0
HKD2_k127_1522321_2 PFAM GGDEF domain containing protein - - - 0.00001682 59.0
HKD2_k127_1532153_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 533.0
HKD2_k127_1532153_1 periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009952 287.0
HKD2_k127_1533540_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 364.0
HKD2_k127_1533540_1 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 357.0
HKD2_k127_1533540_2 WD domain, G-beta repeat - - - 0.000000000000000000000000001004 126.0
HKD2_k127_1533540_3 peptidase M42 family protein - - - 0.00000000000000000009413 91.0
HKD2_k127_1539778_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 394.0
HKD2_k127_1539778_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000002018 211.0
HKD2_k127_1539778_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.0000000000000000000006816 100.0
HKD2_k127_1582124_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 489.0
HKD2_k127_1583576_0 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 556.0
HKD2_k127_1583576_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 349.0
HKD2_k127_1583576_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000088 199.0
HKD2_k127_1583576_3 transferase activity, transferring glycosyl groups K00721 - 2.4.1.83 0.0000000000009179 76.0
HKD2_k127_1585122_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.463e-236 744.0
HKD2_k127_1587534_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 511.0
HKD2_k127_1587534_1 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000001579 241.0
HKD2_k127_1587534_2 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000009271 198.0
HKD2_k127_1587534_3 PFAM Maf family protein K06287 - - 0.0000000000000000000000000000000000000000368 160.0
HKD2_k127_1590487_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.764e-224 704.0
HKD2_k127_1590487_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
HKD2_k127_1590487_2 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000001138 184.0
HKD2_k127_1590487_3 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000011 168.0
HKD2_k127_1590487_4 Transposase IS200 like - - - 0.0000000000000000000000000000000000000003478 155.0
HKD2_k127_1595212_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 544.0
HKD2_k127_1595212_1 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000005424 98.0
HKD2_k127_1616097_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 563.0
HKD2_k127_1616097_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000004224 187.0
HKD2_k127_1631244_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 299.0
HKD2_k127_1631244_1 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000001601 119.0
HKD2_k127_1637386_0 3-carboxyethylcatechol 2,3-dioxygenase activity K04100 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 439.0
HKD2_k127_1637386_1 Polysaccharide deacetylase - - - 0.00000000000000000003542 91.0
HKD2_k127_1654701_0 SMART AAA ATPase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 418.0
HKD2_k127_1670476_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 576.0
HKD2_k127_1670476_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 463.0
HKD2_k127_1670476_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000001474 113.0
HKD2_k127_1686374_0 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000001063 181.0
HKD2_k127_1686374_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000001113 168.0
HKD2_k127_1686374_2 Acetyltransferase (GNAT) K06977 - - 0.00000000000000000000000000000000000000001439 162.0
HKD2_k127_1686374_3 COG NOG16854 non supervised orthologous group - - - 0.00000000000000001164 89.0
HKD2_k127_1686374_4 PFAM Abortive infection protein K07052 - - 0.000002317 55.0
HKD2_k127_1687304_0 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000000000001539 226.0
HKD2_k127_1687304_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001606 120.0
HKD2_k127_1687304_2 carboxylic ester hydrolase activity - - - 0.000000000000003668 80.0
HKD2_k127_1699690_0 Serine threonine protein kinase K08884 - 2.7.11.1 0.00000002573 63.0
HKD2_k127_171817_0 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 576.0
HKD2_k127_172989_0 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000005295 202.0
HKD2_k127_1753617_0 Domain of unknown function (DUF1846) - - - 9.962e-231 723.0
HKD2_k127_1753617_1 Glycosyl transferase family group 2 - - - 1.408e-199 640.0
HKD2_k127_1772583_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 331.0
HKD2_k127_1772583_1 Histidine kinase - - - 0.000000000000000000000000000004346 129.0
HKD2_k127_1772583_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000008328 100.0
HKD2_k127_1772583_3 Histidine kinase K07673 - 2.7.13.3 0.000005302 58.0
HKD2_k127_1772583_4 L-ascorbic acid binding - - - 0.0009065 44.0
HKD2_k127_1773140_0 L-arabinose isomerase K01804 - 5.3.1.4 1.744e-232 728.0
HKD2_k127_1773140_1 L-fucose isomerase, C-terminal domain - - - 4.48e-222 700.0
HKD2_k127_1773140_2 Alcohol dehydrogenase GroES-like domain K00004,K00008,K00098 - 1.1.1.14,1.1.1.264,1.1.1.303,1.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 352.0
HKD2_k127_1773140_3 Membrane component of a K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 326.0
HKD2_k127_1773140_4 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 298.0
HKD2_k127_1781907_0 Glycosyl Hydrolase Family 88 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 400.0
HKD2_k127_1781907_1 - - - - 0.0000006305 55.0
HKD2_k127_1789983_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 405.0
HKD2_k127_1789983_1 Flavin containing amine oxidoreductase K00274,K21639 - 1.4.3.25,1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 300.0
HKD2_k127_1789983_2 PFAM Methyltransferase type K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001008 272.0
HKD2_k127_1789983_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000003774 233.0
HKD2_k127_1789983_4 AAA-like domain - - - 0.0000000000000000000003907 112.0
HKD2_k127_1789983_5 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000001997 89.0
HKD2_k127_1789983_6 - - - - 0.00000000000000636 84.0
HKD2_k127_1790024_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 443.0
HKD2_k127_1790024_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005852 269.0
HKD2_k127_1790024_2 HlyD family secretion protein K02005 - - 0.0000000001243 74.0
HKD2_k127_1815845_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 7.879e-216 683.0
HKD2_k127_1815845_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 287.0
HKD2_k127_1815845_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000906 193.0
HKD2_k127_1815845_3 phenylacetic acid degradation protein PaaD K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000000302 145.0
HKD2_k127_1821721_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.359e-308 964.0
HKD2_k127_1821721_1 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000003344 189.0
HKD2_k127_1821721_2 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000001209 169.0
HKD2_k127_1853169_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000153 223.0
HKD2_k127_1855918_0 PFAM glycoside hydrolase, family 4 K07406 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 396.0
HKD2_k127_1855918_1 unsaturated chondroitin disaccharide hydrolase activity K15532 - 3.2.1.172 0.000000000000000000000000000000000000000006175 162.0
HKD2_k127_186225_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000002007 236.0
HKD2_k127_186225_1 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000008931 196.0
HKD2_k127_186225_2 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000003321 202.0
HKD2_k127_186225_3 HD domain - - - 0.0000000000000000000000000000000000000000000004672 192.0
HKD2_k127_186225_4 helix_turn_helix, Lux Regulon - - - 0.000000001872 62.0
HKD2_k127_1864606_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000002566 173.0
HKD2_k127_1864606_1 Methyltransferase type 11 - - - 0.0000000000000000000000007031 115.0
HKD2_k127_191686_0 Transcriptional regulator K01733,K10439 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 483.0
HKD2_k127_1924007_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 533.0
HKD2_k127_1924007_1 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 436.0
HKD2_k127_1924007_2 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.00001774 47.0
HKD2_k127_1955964_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 569.0
HKD2_k127_1955964_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 372.0
HKD2_k127_1955964_2 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000002916 181.0
HKD2_k127_1956104_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 598.0
HKD2_k127_1956104_1 PFAM peptidase M14, carboxypeptidase A - - - 0.00000000000000000000003299 112.0
HKD2_k127_1960157_0 Nacht domain K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001197 276.0
HKD2_k127_1960157_1 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000000000001246 132.0
HKD2_k127_1962111_0 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 347.0
HKD2_k127_1962111_1 ACT domain K09964 - - 0.000000000000000000000000002958 119.0
HKD2_k127_1962111_2 Cyclic-di-AMP receptor - - - 0.000000000000000002139 87.0
HKD2_k127_1962111_3 COGs COG3870 conserved - - - 0.00000000004635 68.0
HKD2_k127_1979626_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.905e-288 913.0
HKD2_k127_199138_0 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 387.0
HKD2_k127_199138_1 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007485 280.0
HKD2_k127_199138_2 peptide-methionine (S)-S-oxide reductase activity K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000002627 259.0
HKD2_k127_199138_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000005375 209.0
HKD2_k127_199138_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000001927 148.0
HKD2_k127_199138_5 acetyltransferase - - - 0.000000000000000000000000000001697 130.0
HKD2_k127_2003447_0 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 558.0
HKD2_k127_2003447_1 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000006615 178.0
HKD2_k127_2003447_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000001399 175.0
HKD2_k127_2007388_0 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000001562 214.0
HKD2_k127_2007388_1 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000007682 135.0
HKD2_k127_2009980_0 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000182 234.0
HKD2_k127_2009980_1 RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000155 231.0
HKD2_k127_2013251_0 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 309.0
HKD2_k127_2013251_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000005805 103.0
HKD2_k127_2022195_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 379.0
HKD2_k127_2022195_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000006318 227.0
HKD2_k127_2022195_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000005817 160.0
HKD2_k127_2022195_3 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000004207 133.0
HKD2_k127_2022195_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000005386 58.0
HKD2_k127_2025422_0 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000009377 185.0
HKD2_k127_2025422_1 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000001294 78.0
HKD2_k127_2027168_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 548.0
HKD2_k127_2027168_1 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000005293 186.0
HKD2_k127_2027993_0 PFAM N-acylglucosamine 2-epimerase K01787,K16213 - 5.1.3.11,5.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 447.0
HKD2_k127_2027993_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000001304 139.0
HKD2_k127_2027993_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000006291 61.0
HKD2_k127_2038312_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
HKD2_k127_2038312_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000003229 207.0
HKD2_k127_2038312_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000001669 140.0
HKD2_k127_2038312_3 Protein of unknown function (DUF456) K09793 - - 0.00000000000000001905 90.0
HKD2_k127_2062785_0 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000004929 233.0
HKD2_k127_2062785_1 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000007118 194.0
HKD2_k127_2062785_2 PFAM Stage V sporulation protein S K06416 - - 0.000000000000000000000000001274 123.0
HKD2_k127_2062785_3 Belongs to the bacterial histone-like protein family - - - 0.00000001341 63.0
HKD2_k127_2064186_0 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 376.0
HKD2_k127_2064186_1 Bile acid beta-glucosidase K17108 - 3.2.1.45 0.0000000000000000000000000000000001378 154.0
HKD2_k127_2069823_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000454 209.0
HKD2_k127_2069823_1 UbiD family decarboxylase - - - 0.00002208 49.0
HKD2_k127_207737_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.939e-317 983.0
HKD2_k127_207737_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000002143 221.0
HKD2_k127_2081499_0 SPFH domain / Band 7 family - - - 1.542e-259 814.0
HKD2_k127_2086373_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000687 156.0
HKD2_k127_2086373_1 - - - - 0.000000007753 67.0
HKD2_k127_2091649_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 489.0
HKD2_k127_2104733_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 347.0
HKD2_k127_2104733_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 342.0
HKD2_k127_2104733_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 318.0
HKD2_k127_2104733_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
HKD2_k127_2104733_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004594 248.0
HKD2_k127_2104733_5 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000002204 228.0
HKD2_k127_2109985_0 COG2211 Na melibiose symporter and related K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001598 248.0
HKD2_k127_2109985_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000001402 156.0
HKD2_k127_2116489_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.194e-241 752.0
HKD2_k127_2121931_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 326.0
HKD2_k127_2121931_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000008864 249.0
HKD2_k127_2123145_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 1.274e-232 736.0
HKD2_k127_2123145_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000001192 199.0
HKD2_k127_2135672_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 391.0
HKD2_k127_2135672_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 343.0
HKD2_k127_2135672_2 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 293.0
HKD2_k127_2149343_0 FtsK/SpoIIIE family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 504.0
HKD2_k127_2171825_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 601.0
HKD2_k127_2171825_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000006531 63.0
HKD2_k127_217217_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 331.0
HKD2_k127_217217_1 phosphorelay signal transduction system - - - 0.0000000000000000000003393 111.0
HKD2_k127_2189253_0 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000001958 233.0
HKD2_k127_2189253_1 Uncharacterized conserved protein (DUF2249) K07322 - - 0.000000000000000000000000000007585 124.0
HKD2_k127_2189688_0 membrane - - - 0.000000000000000000000000005229 127.0
HKD2_k127_2190777_0 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004296 278.0
HKD2_k127_2192139_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 560.0
HKD2_k127_2195681_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 377.0
HKD2_k127_2195681_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000008925 139.0
HKD2_k127_2195681_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000007631 80.0
HKD2_k127_2198029_0 - - - - 0.0000000000000001168 89.0
HKD2_k127_2198029_1 domain protein K14194 - - 0.0000008839 61.0
HKD2_k127_2225044_0 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 435.0
HKD2_k127_2225044_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000004905 97.0
HKD2_k127_2228059_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000003811 234.0
HKD2_k127_2228059_1 transcriptional regulator domain protein - - - 0.0000000000000000000000006202 114.0
HKD2_k127_2228059_2 Protein tyrosine kinase - - - 0.00000000000004475 73.0
HKD2_k127_2228059_3 - - - - 0.0003445 51.0
HKD2_k127_2238386_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 407.0
HKD2_k127_2238386_1 Two component transcriptional regulator, winged helix family K07670 - - 0.00001172 57.0
HKD2_k127_2248519_0 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 313.0
HKD2_k127_2248519_1 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000000000000003577 108.0
HKD2_k127_2248646_0 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 302.0
HKD2_k127_2248646_1 Butirosin biosynthesis protein H, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005831 280.0
HKD2_k127_2255136_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 442.0
HKD2_k127_2255136_1 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.0000000000000000000000000000000000000281 149.0
HKD2_k127_2255136_2 PFAM Amino acid-binding ACT - - - 0.000000000000000000000000000000000009149 139.0
HKD2_k127_2255136_3 phosphatidate phosphatase activity - - - 0.0000000000000000000000003162 115.0
HKD2_k127_2259828_0 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 342.0
HKD2_k127_2259828_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 319.0
HKD2_k127_2259828_2 N-4 methylation of cytosine K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000001639 237.0
HKD2_k127_2270524_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 591.0
HKD2_k127_2275779_0 PFAM ABC transporter related K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000004853 201.0
HKD2_k127_2275779_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000005974 185.0
HKD2_k127_2275779_2 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000003131 133.0
HKD2_k127_2277298_0 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 344.0
HKD2_k127_2277298_1 Domain of unknown function (DUF348) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 319.0
HKD2_k127_2277298_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000008337 223.0
HKD2_k127_2277298_3 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000022 175.0
HKD2_k127_2277298_4 Carotenoid biosynthesis protein - - - 0.00000000000002569 77.0
HKD2_k127_2284513_0 ATPase (P-type) K01535 - 3.6.3.6 9.345e-256 801.0
HKD2_k127_2305677_0 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000005823 198.0
HKD2_k127_2305677_1 PFAM CAAX amino terminal protease family - - - 0.00000000000001951 81.0
HKD2_k127_2312628_0 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000001161 71.0
HKD2_k127_2312969_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 572.0
HKD2_k127_2330234_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 8.589e-209 665.0
HKD2_k127_2338792_0 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 400.0
HKD2_k127_2338792_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008143 265.0
HKD2_k127_2355853_0 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 325.0
HKD2_k127_2379146_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 358.0
HKD2_k127_2379146_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000001202 158.0
HKD2_k127_2382945_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 467.0
HKD2_k127_2382945_1 FAD linked oxidase domain protein K00803 - 2.5.1.26 0.00000000000000009479 83.0
HKD2_k127_2396280_0 PFAM VanW family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 480.0
HKD2_k127_2396280_1 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000005331 230.0
HKD2_k127_2396280_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000007525 152.0
HKD2_k127_240904_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 500.0
HKD2_k127_240904_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 364.0
HKD2_k127_240904_2 Domain of unknown function (DUF4349) - - - 0.000000000000000000000005982 111.0
HKD2_k127_2412645_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 534.0
HKD2_k127_2418126_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002769 263.0
HKD2_k127_2418126_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000006044 200.0
HKD2_k127_2418126_2 - - - - 0.00000000000000000000000000000000000000000000000002198 187.0
HKD2_k127_2418126_3 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000003021 130.0
HKD2_k127_2428823_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 531.0
HKD2_k127_2428823_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0000000000000000002972 89.0
HKD2_k127_2441898_0 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000495 203.0
HKD2_k127_2441898_1 Protein of unknown function (DUF2812) - - - 0.00000000000000000000000000006936 123.0
HKD2_k127_2450673_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733,K22010 - 4.2.3.1 5.307e-202 644.0
HKD2_k127_2450673_1 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 459.0
HKD2_k127_2450673_2 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000003335 229.0
HKD2_k127_2450673_3 PFAM response regulator receiver K11443 - - 0.000000000000000000000000000000000001375 141.0
HKD2_k127_2450673_4 protein histidine kinase activity K01768,K11527,K18143 - 2.7.13.3,4.6.1.1 0.00000000000000000004985 94.0
HKD2_k127_2462223_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 421.0
HKD2_k127_2462223_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 339.0
HKD2_k127_2465834_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 299.0
HKD2_k127_2465834_1 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000481 160.0
HKD2_k127_2465834_2 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000001363 164.0
HKD2_k127_2465834_3 - - - - 0.0000000000000000000000014 117.0
HKD2_k127_2465834_4 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000002298 94.0
HKD2_k127_2465834_5 Domain of unknown function (DUF1330) - - - 0.00000000000002418 80.0
HKD2_k127_2470767_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 345.0
HKD2_k127_2470767_1 Histidine kinase - - - 0.0003383 53.0
HKD2_k127_2479556_0 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000000000000000003412 139.0
HKD2_k127_2479556_1 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000000000000000000000000009914 135.0
HKD2_k127_2479556_2 efflux transmembrane transporter activity K02004 - - 0.000275 53.0
HKD2_k127_2480280_0 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000003662 228.0
HKD2_k127_2480280_1 ATP-dependent transcriptional regulator, MalT-like, LuxR family K03556 - - 0.000000000000001662 78.0
HKD2_k127_2480280_2 Esterase K01070 - 3.1.2.12 0.0002182 53.0
HKD2_k127_2482673_0 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000002282 269.0
HKD2_k127_2482673_1 domain, Protein - - - 0.00000000000000000000000000000000000000000009711 183.0
HKD2_k127_2482673_2 beta-galactosidase activity - - - 0.000001415 62.0
HKD2_k127_2483547_0 - - - - 0.0000000000000000000001068 107.0
HKD2_k127_2483547_1 - - - - 0.0000000008293 65.0
HKD2_k127_2490307_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00000000000000000000000126 106.0
HKD2_k127_2517541_0 acetyltransferase - - - 0.000000000000000000000000000000000000000003987 159.0
HKD2_k127_2517541_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000009378 120.0
HKD2_k127_2517541_2 Protein of unknown function (DUF3795) - - - 0.0000000000000000002387 92.0
HKD2_k127_2521570_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 492.0
HKD2_k127_2521570_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000004028 211.0
HKD2_k127_2521570_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000002207 140.0
HKD2_k127_2525949_0 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 311.0
HKD2_k127_2525949_1 heme binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000009411 241.0
HKD2_k127_2525949_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000005697 172.0
HKD2_k127_2525949_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000002116 162.0
HKD2_k127_2525949_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000001402 153.0
HKD2_k127_2527342_0 - - - - 0.000000000000000000000000000004142 130.0
HKD2_k127_2528407_0 ABC transporter transmembrane region - - - 2.092e-221 702.0
HKD2_k127_2528407_1 ABC transporter transmembrane region - - - 7.695e-212 675.0
HKD2_k127_2528407_2 ABC-type multidrug transport system ATPase K01990,K16907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 296.0
HKD2_k127_2528407_3 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000001257 237.0
HKD2_k127_2528407_4 transmembrane transporter activity K05820 - - 0.00000000000000000000000000000000000000000000000000001929 203.0
HKD2_k127_2528407_5 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000005373 193.0
HKD2_k127_2528407_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000702 160.0
HKD2_k127_2528407_7 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000001329 162.0
HKD2_k127_2528407_8 - - - - 0.0000000000000000000000001182 110.0
HKD2_k127_254017_0 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000002725 138.0
HKD2_k127_254017_1 Lamin Tail Domain - - - 0.0000000000000000000006531 111.0
HKD2_k127_254017_2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000001059 103.0
HKD2_k127_254017_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000001609 103.0
HKD2_k127_254017_4 Spore coat protein CotH - - - 0.00000002517 67.0
HKD2_k127_2556540_0 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 310.0
HKD2_k127_2556540_1 Cadherin repeats. - - - 0.0000000000000000000000000000000000004501 155.0
HKD2_k127_2556540_2 cell adhesion involved in biofilm formation K13735 - - 0.000000000000000009066 93.0
HKD2_k127_2577380_0 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 316.0
HKD2_k127_2588838_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009027 255.0
HKD2_k127_2588838_1 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000003043 171.0
HKD2_k127_2589879_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 402.0
HKD2_k127_2589879_1 Protein of unknown function (DUF1475) - - - 0.00000000000000000000000000000005926 129.0
HKD2_k127_2589879_3 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000002604 52.0
HKD2_k127_2592342_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 423.0
HKD2_k127_2592342_1 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 353.0
HKD2_k127_2592342_2 Predicted membrane protein (DUF2085) - - - 0.000000000000002288 78.0
HKD2_k127_2597666_0 Nitroreductase family K19286 - 1.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 259.0
HKD2_k127_2597666_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000003094 241.0
HKD2_k127_2597666_2 Domain of unknown function (DUF4111) K00984 - 2.7.7.47 0.000000000000000000000000000000000000000000000000000000000000000004504 233.0
HKD2_k127_2597666_3 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000699 210.0
HKD2_k127_2604386_0 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 351.0
HKD2_k127_2604386_1 Transglycosylase SLT domain - - - 0.0000000001147 67.0
HKD2_k127_2606841_0 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 - 2.6.1.13 9.57e-205 642.0
HKD2_k127_2606841_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 331.0
HKD2_k127_2606841_2 Streptomycin adenylyltransferase K05593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001467 259.0
HKD2_k127_2606841_3 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000001257 114.0
HKD2_k127_2606841_4 methyltransferase - - - 0.000000000000000000004037 96.0
HKD2_k127_2613107_0 - - - - 0.000000000000000000000000000000006777 136.0
HKD2_k127_261390_0 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001298 259.0
HKD2_k127_261390_1 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000004088 129.0
HKD2_k127_2625605_0 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 340.0
HKD2_k127_2628539_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 482.0
HKD2_k127_2628539_1 PFAM cytochrome bd ubiquinol oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 359.0
HKD2_k127_2628539_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003717 279.0
HKD2_k127_2628539_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000004445 83.0
HKD2_k127_2636891_0 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 477.0
HKD2_k127_2636891_1 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005076 271.0
HKD2_k127_2640123_0 Belongs to the SEDS family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 333.0
HKD2_k127_2664286_0 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000005096 202.0
HKD2_k127_2664286_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000144 132.0
HKD2_k127_2672911_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 452.0
HKD2_k127_2675670_0 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000000000000001707 227.0
HKD2_k127_2675670_1 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000000000000003927 215.0
HKD2_k127_2675670_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000004512 198.0
HKD2_k127_2675670_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000001151 160.0
HKD2_k127_2675670_4 Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.000000000000000000000000000000000000003223 147.0
HKD2_k127_2676229_0 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000002357 197.0
HKD2_k127_2676229_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000002203 154.0
HKD2_k127_2676229_3 Transport permease protein K01992 - - 0.0009062 51.0
HKD2_k127_2686252_0 Transcriptional regulator K02529,K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 505.0
HKD2_k127_268675_0 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 293.0
HKD2_k127_268675_1 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 291.0
HKD2_k127_268675_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001833 261.0
HKD2_k127_2695453_0 purine nucleotide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 337.0
HKD2_k127_2695453_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000004081 211.0
HKD2_k127_2695453_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000004679 123.0
HKD2_k127_2695453_3 Domain of unknown function (DUF4032) - - - 0.00000000000000000007608 99.0
HKD2_k127_2706234_0 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 317.0
HKD2_k127_2706234_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000002629 173.0
HKD2_k127_2707930_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 520.0
HKD2_k127_2716221_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 2.013e-204 656.0
HKD2_k127_2716221_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000642 87.0
HKD2_k127_272916_0 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.0000000000000000000000000000000000000000000000000000000000006229 216.0
HKD2_k127_272916_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000002618 188.0
HKD2_k127_272916_2 PFAM diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000005756 117.0
HKD2_k127_272916_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000001586 98.0
HKD2_k127_272916_4 RNHCP domain - - - 0.00000000000000007913 94.0
HKD2_k127_273138_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 572.0
HKD2_k127_273138_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000007575 188.0
HKD2_k127_273138_2 tryptophan synthase K01694 GO:0000162,GO:0003674,GO:0003824,GO:0004834,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.0000000000000000000000000002254 117.0
HKD2_k127_273138_3 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000001749 75.0
HKD2_k127_2738776_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 354.0
HKD2_k127_2738776_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000003487 237.0
HKD2_k127_2738776_2 PFAM ABC transporter related K01990 - - 0.000185 46.0
HKD2_k127_2744112_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007718 292.0
HKD2_k127_2744112_1 extracellular polysaccharide biosynthetic process K13582 - - 0.00003714 49.0
HKD2_k127_2753803_0 Fibronectin type III-like domain K05349 - 3.2.1.21 3.513e-251 796.0
HKD2_k127_2753803_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000000006143 199.0
HKD2_k127_2753803_2 arylsulfatase activity - - - 0.00004703 54.0
HKD2_k127_2761982_0 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 489.0
HKD2_k127_2761982_1 - - - - 0.000000000000000000001839 104.0
HKD2_k127_2769168_0 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000004126 101.0
HKD2_k127_2799674_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 284.0
HKD2_k127_2799674_1 binding domain protein - - - 0.0000000000000000000000000000000000000001517 159.0
HKD2_k127_2799674_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 0.000000000000003576 77.0
HKD2_k127_2808377_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008783 290.0
HKD2_k127_2817123_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
HKD2_k127_2817123_1 COG0524 Sugar kinases, ribokinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000208 263.0
HKD2_k127_2817123_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000003465 238.0
HKD2_k127_2817123_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.000000000000000000000000000000000000000000000004752 176.0
HKD2_k127_2817123_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000003373 128.0
HKD2_k127_281869_0 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000001628 231.0
HKD2_k127_281869_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000198 220.0
HKD2_k127_282093_0 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590,K07319 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 351.0
HKD2_k127_282093_1 AAA ATPase domain - - - 0.00000000000000006889 81.0
HKD2_k127_282528_0 self proteolysis - - - 0.000005446 59.0
HKD2_k127_2832241_0 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 2.247e-198 627.0
HKD2_k127_2832241_1 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 381.0
HKD2_k127_2832241_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006546 278.0
HKD2_k127_2834236_0 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 471.0
HKD2_k127_2834236_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 436.0
HKD2_k127_2834236_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 340.0
HKD2_k127_2851057_0 Glycosyl transferase family group 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 328.0
HKD2_k127_2853998_0 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 4.437e-214 705.0
HKD2_k127_2853998_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 428.0
HKD2_k127_2853998_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 381.0
HKD2_k127_2853998_3 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 314.0
HKD2_k127_2853998_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003046 257.0
HKD2_k127_2853998_5 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000003528 244.0
HKD2_k127_2853998_6 Periplasmic binding protein domain K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000009843 237.0
HKD2_k127_2853998_7 PFAM HI0933 family protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000164 231.0
HKD2_k127_2853998_8 FR47-like protein K03829 - - 0.0000000000000000000000000000000000000000000000000428 183.0
HKD2_k127_2859984_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003496 288.0
HKD2_k127_2859984_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002658 279.0
HKD2_k127_2859984_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 270.0
HKD2_k127_2859984_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000001368 78.0
HKD2_k127_2859984_4 ATP hydrolysis coupled proton transport - - - 0.0000000004102 73.0
HKD2_k127_2867509_0 nitrogen compound transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000001125 209.0
HKD2_k127_2867509_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000001166 113.0
HKD2_k127_2867509_2 protein histidine kinase activity K02484,K07642 - 2.7.13.3 0.000000000000000000001443 96.0
HKD2_k127_2874637_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 337.0
HKD2_k127_2874637_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000002347 134.0
HKD2_k127_2878789_0 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001224 254.0
HKD2_k127_2878789_1 hydrolase, family 3 K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000002633 231.0
HKD2_k127_2878789_2 PFAM ABC transporter related - - - 0.000003242 53.0
HKD2_k127_2882366_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 608.0
HKD2_k127_2882366_1 - - - - 0.00000000005845 66.0
HKD2_k127_2892828_0 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 517.0
HKD2_k127_2892828_1 PFAM RNA binding S1 domain protein K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 393.0
HKD2_k127_2892828_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000008277 130.0
HKD2_k127_2897358_0 Glycosyltransferase like family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000407 246.0
HKD2_k127_2897358_2 - - - - 0.0000000000000000000000000000000000000000002018 168.0
HKD2_k127_2897358_3 TPR repeat - - - 0.000000000000000000000000000000000000876 154.0
HKD2_k127_2903946_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 336.0
HKD2_k127_2903946_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001438 153.0
HKD2_k127_2903946_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000002305 112.0
HKD2_k127_2903946_3 Tfp pilus assembly protein FimV - - - 0.00000000002401 76.0
HKD2_k127_2908020_0 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 605.0
HKD2_k127_2908020_1 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000006264 193.0
HKD2_k127_2908020_2 ECF-type riboflavin transporter, S component K16924 - - 0.00000000000000000000000000004296 129.0
HKD2_k127_2910467_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006274 239.0
HKD2_k127_2910467_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000211 88.0
HKD2_k127_2916155_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 349.0
HKD2_k127_2916155_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000001332 66.0
HKD2_k127_2916897_0 Glycosyltransferase 36 associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 621.0
HKD2_k127_2916897_1 PFAM extracellular solute-binding protein family 1 K02027 - - 0.00000000000000000000000000000000002668 142.0
HKD2_k127_2928482_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1154.0
HKD2_k127_2931426_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001816 263.0
HKD2_k127_2931426_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000001564 154.0
HKD2_k127_2942159_0 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000003293 193.0
HKD2_k127_2942159_1 CAAX protease self-immunity K07052 - - 0.0000000002014 71.0
HKD2_k127_294607_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000004319 74.0
HKD2_k127_2958773_0 OsmC-like protein K07397 - - 0.00000000000000000000001601 106.0
HKD2_k127_2958773_1 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.000000000003171 76.0
HKD2_k127_2959531_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 480.0
HKD2_k127_2959531_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.00000000000000000000000000000000652 136.0
HKD2_k127_2965497_0 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000634 184.0
HKD2_k127_2965497_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000008343 124.0
HKD2_k127_2985541_0 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 316.0
HKD2_k127_2985541_1 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000002148 224.0
HKD2_k127_2985541_2 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000003157 176.0
HKD2_k127_2985541_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000001024 142.0
HKD2_k127_2987727_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 442.0
HKD2_k127_2987727_1 carboxylic ester hydrolase activity K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001251 269.0
HKD2_k127_2987727_2 PFAM MerR family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005536 238.0
HKD2_k127_2987727_3 dihydrofolate reductase activity K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000004995 178.0
HKD2_k127_2987727_4 - - - - 0.000000000000000000000000001238 113.0
HKD2_k127_2987727_5 DNA alkylation repair enzyme - - - 0.0003983 51.0
HKD2_k127_2990908_0 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 302.0
HKD2_k127_2990908_1 GNAT acetyltransferase - - - 0.00001097 56.0
HKD2_k127_2993843_0 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 593.0
HKD2_k127_2993843_1 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 352.0
HKD2_k127_3008983_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001874 275.0
HKD2_k127_3012239_0 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 323.0
HKD2_k127_3030386_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 342.0
HKD2_k127_3030386_1 Domain of unknown function (DUF3597) - - - 0.000000000000000000000000000002555 124.0
HKD2_k127_3036604_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004949 262.0
HKD2_k127_3040761_0 PFAM Glycosidase K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 403.0
HKD2_k127_3040761_1 YdjC-like protein K03478 - 3.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 319.0
HKD2_k127_3040761_2 - - - - 0.000000000000000000000000000000000000000002067 156.0
HKD2_k127_3052016_0 Ion channel - - - 0.000000000000000000000000001394 117.0
HKD2_k127_3052016_1 Lipoprotein K05811 - - 0.0000000000000859 74.0
HKD2_k127_3052016_2 transmembrane transport K16052 - - 0.00000000007249 67.0
HKD2_k127_3062291_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003078 250.0
HKD2_k127_3062291_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000003437 183.0
HKD2_k127_3062291_2 Regulatory protein MarR - - - 0.00000000000000000000000000088 118.0
HKD2_k127_3068102_0 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000001008 278.0
HKD2_k127_3068102_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000689 167.0
HKD2_k127_3068102_2 hydrolase activity, acting on ester bonds K15357,K19311 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0044237,GO:0044248 3.5.1.106 0.00000000000000000000000000006391 119.0
HKD2_k127_3074987_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 470.0
HKD2_k127_3075457_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 445.0
HKD2_k127_3075457_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 282.0
HKD2_k127_3075457_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001379 262.0
HKD2_k127_3075457_3 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000001336 170.0
HKD2_k127_307566_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 319.0
HKD2_k127_3079267_0 peptidyl-tyrosine sulfation - - - 0.00000002521 64.0
HKD2_k127_3082441_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 572.0
HKD2_k127_3082441_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 418.0
HKD2_k127_3089253_0 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000994 83.0
HKD2_k127_3089253_1 Phosphotransferase enzyme family - - - 0.0000796 53.0
HKD2_k127_3089612_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 5.757e-209 654.0
HKD2_k127_3089612_1 glutamate synthase alpha subunit domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 325.0
HKD2_k127_3105376_0 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 466.0
HKD2_k127_3105376_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 379.0
HKD2_k127_3105376_2 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 374.0
HKD2_k127_3126792_0 WD40 repeats K20332 - - 0.0000000000000000000002562 112.0
HKD2_k127_3130501_0 COGs COG3533 conserved K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 469.0
HKD2_k127_3131163_0 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 605.0
HKD2_k127_3131163_1 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 0.0000000000000000001786 87.0
HKD2_k127_3138913_0 NlpC/P60 family K20742,K21471 - 3.4.14.13 0.000000000000000000000000000000000003065 153.0
HKD2_k127_3141593_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 332.0
HKD2_k127_3141593_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000003389 131.0
HKD2_k127_3141593_2 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000003058 129.0
HKD2_k127_3147774_0 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000007448 212.0
HKD2_k127_3147774_1 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025,K08723 - 3.1.3.5 0.000000000000000000000000000000000000000000001809 173.0
HKD2_k127_3152099_0 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000009356 174.0
HKD2_k127_3152099_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000002498 174.0
HKD2_k127_3159977_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K02169,K02170,K08680,K10216,K15756,K16264 - 2.1.1.197,3.1.1.85,3.7.1.13,3.7.1.9,4.2.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 453.0
HKD2_k127_3159977_1 transcriptional regulator K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
HKD2_k127_3159977_2 COGs COG3533 conserved K09955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002191 252.0
HKD2_k127_3162474_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000003315 202.0
HKD2_k127_3166887_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 409.0
HKD2_k127_3188429_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000003849 64.0
HKD2_k127_3194607_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003834 276.0
HKD2_k127_3194607_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000001614 136.0
HKD2_k127_3222526_0 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 463.0
HKD2_k127_3222526_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 347.0
HKD2_k127_3237900_0 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 334.0
HKD2_k127_3261603_0 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 297.0
HKD2_k127_3261603_1 PFAM PfkB domain protein - - - 0.0000000000000000005022 89.0
HKD2_k127_3277458_0 Tricorn protease C1 domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 480.0
HKD2_k127_3280021_0 Coenzyme F420-reducing hydrogenase, alpha subunit K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 472.0
HKD2_k127_3280021_1 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 299.0
HKD2_k127_3280021_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 295.0
HKD2_k127_3280021_3 PFAM Vitamin K epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000000003679 228.0
HKD2_k127_3280021_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000000000000000001695 163.0
HKD2_k127_3280021_5 Hydrogenase maturation K03605 - - 0.000000000001205 79.0
HKD2_k127_3304614_0 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 376.0
HKD2_k127_3304614_1 Bacterial sugar transferase - - - 0.000000000000000000000000000004595 127.0
HKD2_k127_3304614_2 PFAM glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00001111 55.0
HKD2_k127_3312874_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 372.0
HKD2_k127_3312874_1 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000008069 245.0
HKD2_k127_3312874_3 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000003444 183.0
HKD2_k127_3315883_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 339.0
HKD2_k127_3327547_0 DnaJ C terminal domain K05516 - - 0.000000000001045 74.0
HKD2_k127_3335144_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.773e-200 632.0
HKD2_k127_3335144_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
HKD2_k127_3335144_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000008145 248.0
HKD2_k127_3343543_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 392.0
HKD2_k127_3343543_1 YHYH protein - - - 0.0000000000000000000000000000000000000002195 157.0
HKD2_k127_3345733_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000002454 228.0
HKD2_k127_3348087_0 Phytoene dehydrogenase K15745 - 1.3.99.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 439.0
HKD2_k127_3350053_0 - - - - 0.0000004889 54.0
HKD2_k127_3366317_0 domain, Protein - - - 0.000000000000000000000000000000003841 148.0
HKD2_k127_3375109_0 Alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000002854 224.0
HKD2_k127_3375109_1 Alpha mannosidase, middle domain K01191,K15524,K16869 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 2.3.1.204,3.2.1.170,3.2.1.24 0.0000000000000000000000000000000000008712 140.0
HKD2_k127_3377222_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000005322 241.0
HKD2_k127_3377222_1 Glycosyl transferase group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000102 136.0
HKD2_k127_3377222_2 Glycosyl transferase group 1 K13668 - 2.4.1.346 0.000000000000000000000000000002097 134.0
HKD2_k127_3377222_3 Oxidoreductase family, NAD-binding Rossmann fold K19181 - 1.1.1.292 0.0000000000000000000000002554 119.0
HKD2_k127_3377222_4 - - - - 0.0001668 54.0
HKD2_k127_3379802_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 6.594e-228 712.0
HKD2_k127_3379802_1 MazG-like family - - - 0.000000000000000000000000000008694 122.0
HKD2_k127_3379802_2 Calcineurin-like phosphoesterase - - - 0.00000000000000003083 87.0
HKD2_k127_3380981_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 569.0
HKD2_k127_3399471_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 593.0
HKD2_k127_3399471_1 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000000005329 112.0
HKD2_k127_3406930_0 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000006306 148.0
HKD2_k127_3414923_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000001855 168.0
HKD2_k127_3442685_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 423.0
HKD2_k127_3442685_1 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000425 80.0
HKD2_k127_3443399_0 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 421.0
HKD2_k127_3445159_0 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 383.0
HKD2_k127_3445159_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 351.0
HKD2_k127_3456641_0 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000005706 124.0
HKD2_k127_3456641_1 Glycosyl transferases group 1 - - - 0.00000000000000000000009229 114.0
HKD2_k127_3456924_0 LysM domain - - - 0.000000000000000000000000000000000001003 142.0
HKD2_k127_3456924_1 FHA domain - - - 0.000003461 59.0
HKD2_k127_346530_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 366.0
HKD2_k127_3465847_0 PFAM Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 507.0
HKD2_k127_3465847_1 nitrogen fixation - - - 0.00000000000000000000000000001398 123.0
HKD2_k127_347982_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 398.0
HKD2_k127_347982_1 ABC-3 protein K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000274 278.0
HKD2_k127_3481004_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 308.0
HKD2_k127_3484041_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000149 81.0
HKD2_k127_3485187_1 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000003781 104.0
HKD2_k127_3485187_2 radical SAM K06871 - - 0.0000001289 62.0
HKD2_k127_3493683_0 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 444.0
HKD2_k127_35120_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 426.0
HKD2_k127_35120_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000427 227.0
HKD2_k127_35120_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000007262 85.0
HKD2_k127_3523315_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002798 257.0
HKD2_k127_354550_0 ATP hydrolysis coupled proton transport - - - 0.000000000000000000000000157 113.0
HKD2_k127_3556830_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1343.0
HKD2_k127_3556830_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 443.0
HKD2_k127_3556830_2 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.000000000000000000000000000000000000000000000002416 176.0
HKD2_k127_3557267_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 368.0
HKD2_k127_3557267_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000004201 190.0
HKD2_k127_3557267_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000008908 119.0
HKD2_k127_3559633_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000001059 143.0
HKD2_k127_3560951_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 475.0
HKD2_k127_3560951_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000004911 162.0
HKD2_k127_3560951_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000002177 68.0
HKD2_k127_3562351_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000000000001203 211.0
HKD2_k127_3562351_1 Methyltransferase domain K06219 - - 0.0000000000000000000000001756 110.0
HKD2_k127_3562351_2 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000000000000000001465 104.0
HKD2_k127_3562823_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 392.0
HKD2_k127_3562823_1 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002805 244.0
HKD2_k127_3562823_2 - - - - 0.00000000000000000000000000000000000371 152.0
HKD2_k127_3562823_3 - - - - 0.000007924 51.0
HKD2_k127_3565297_0 NurA - - - 0.0000000000000000000000000000002306 138.0
HKD2_k127_356944_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004456 235.0
HKD2_k127_357261_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000001405 213.0
HKD2_k127_357261_1 CHASE2 - - - 0.000000000009641 70.0
HKD2_k127_357676_0 copper-translocating P-type ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 346.0
HKD2_k127_357676_1 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002924 286.0
HKD2_k127_357676_2 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000004605 73.0
HKD2_k127_3599438_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 400.0
HKD2_k127_3599438_1 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000003924 168.0
HKD2_k127_3623606_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.841e-249 783.0
HKD2_k127_3626234_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.718e-271 856.0
HKD2_k127_3626234_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 407.0
HKD2_k127_3641747_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000065 218.0
HKD2_k127_3641747_1 - - - - 0.0000000000000000000000000000000000000009926 156.0
HKD2_k127_3655290_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 433.0
HKD2_k127_3655290_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000004962 113.0
HKD2_k127_3656184_0 GHMP kinases C terminal K00054,K00869,K01641 - 1.1.1.88,2.3.3.10,2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000003082 219.0
HKD2_k127_3656184_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000004767 202.0
HKD2_k127_3672542_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 390.0
HKD2_k127_3672542_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 299.0
HKD2_k127_3672542_2 Protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000002208 136.0
HKD2_k127_3672542_3 PFAM Transglycosylase-associated protein - - - 0.00000000000000001176 87.0
HKD2_k127_3707767_0 Pfam:KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 572.0
HKD2_k127_3707767_1 KaiB K08481 - - 0.00000000000000000000000000000000000005287 151.0
HKD2_k127_3707767_2 KaiB K08481 - - 0.000000000000000000000000000000009957 137.0
HKD2_k127_3707767_3 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.00000000000000000000000000002053 132.0
HKD2_k127_3707767_4 Histidine kinase - - - 0.0001178 54.0
HKD2_k127_3710931_0 Tetratricopeptide repeats - - - 0.00000002243 66.0
HKD2_k127_3711242_0 carboxylic ester hydrolase activity K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007952 274.0
HKD2_k127_3711242_2 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000003554 224.0
HKD2_k127_3711242_4 PFAM RNP-1 like RNA-binding protein - - - 0.0000000000000000000000005618 108.0
HKD2_k127_3721648_0 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 343.0
HKD2_k127_3721648_1 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 323.0
HKD2_k127_3721648_2 - - - - 0.00000000000000000000004701 103.0
HKD2_k127_3721648_3 histone H2A K63-linked ubiquitination - - - 0.0000001422 54.0
HKD2_k127_3721648_4 mevalonate kinase K00869 - 2.7.1.36 0.0001268 53.0
HKD2_k127_3721988_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 465.0
HKD2_k127_3721988_1 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10545,K10548 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
HKD2_k127_3746452_0 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000001024 153.0
HKD2_k127_3746452_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.000000000000000000000005605 104.0
HKD2_k127_3746452_2 Protein of unknown function (DUF1232) - - - 0.00000002536 60.0
HKD2_k127_3749327_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005416 273.0
HKD2_k127_37500_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1122.0
HKD2_k127_37500_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 563.0
HKD2_k127_37500_2 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 382.0
HKD2_k127_37500_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 336.0
HKD2_k127_37500_4 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000002457 237.0
HKD2_k127_37500_5 Domain of unknown function (DUF4340) - - - 0.0006012 50.0
HKD2_k127_3764083_0 Domain of unknown function (DUF5109) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 438.0
HKD2_k127_3764083_1 PFAM N-acylglucosamine 2-epimerase K01787 - 5.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002996 280.0
HKD2_k127_3792064_0 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002174 266.0
HKD2_k127_3801502_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 470.0
HKD2_k127_3801762_2 transcription factor binding - - - 0.00000000000008635 71.0
HKD2_k127_3807624_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001897 241.0
HKD2_k127_3807624_1 Roadblock/LC7 domain K07131 - - 0.00000000000000000000000000003258 128.0
HKD2_k127_3807624_3 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 0.000004706 51.0
HKD2_k127_380969_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 399.0
HKD2_k127_380969_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 376.0
HKD2_k127_380969_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000002142 188.0
HKD2_k127_3811630_0 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000009532 187.0
HKD2_k127_3811630_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000001383 158.0
HKD2_k127_382030_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.516e-245 767.0
HKD2_k127_382030_1 aminopeptidase activity K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 403.0
HKD2_k127_382030_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000627 257.0
HKD2_k127_382030_3 Capsular polysaccharide synthesis protein - - - 0.000000000000000000000002013 107.0
HKD2_k127_3825127_0 Catalyzes the NADPH-dependent reduction of LysW - aminoadipate 6-phosphate to yield LysW -aminoadipate 6- semialdehyde K05829 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 444.0
HKD2_k127_3825127_1 Belongs to the acetylglutamate kinase family. LysZ subfamily K05828 - - 0.00000000000000000000000000000000000000009613 154.0
HKD2_k127_3827268_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002422 270.0
HKD2_k127_3827268_1 YCII-related domain - - - 0.000000000000000000000000000000000000000000000002644 177.0
HKD2_k127_3847287_0 Hydroxymethylglutaryl-coenzyme A reductase K00054,K00626 - 1.1.1.88,2.3.1.9 0.000000000000000000000000000000000000003521 154.0
HKD2_k127_3847287_1 glycosyl transferase family 2 - - - 0.000000000000000004347 93.0
HKD2_k127_3847287_2 - - - - 0.00000001146 65.0
HKD2_k127_3850153_0 Alpha-Mannosidase K01191,K15524 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 3.2.1.170,3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 423.0
HKD2_k127_3852607_0 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 409.0
HKD2_k127_3852607_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000009828 221.0
HKD2_k127_3852607_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000006099 139.0
HKD2_k127_385369_0 Serine Threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000007567 232.0
HKD2_k127_3854559_0 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 490.0
HKD2_k127_3854559_1 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000000000000001099 143.0
HKD2_k127_3865383_0 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000882 162.0
HKD2_k127_3865383_1 lipid binding K14954,K14955 GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005543,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008289,GO:0009405,GO:0009605,GO:0009607,GO:0009966,GO:0010469,GO:0010646,GO:0016020,GO:0020012,GO:0023051,GO:0030312,GO:0030545,GO:0030682,GO:0031982,GO:0035091,GO:0042783,GO:0042785,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043230,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044421,GO:0044464,GO:0048018,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051812,GO:0051832,GO:0051834,GO:0051861,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0065009,GO:0071944,GO:0075136,GO:0097367,GO:0097691,GO:0098772,GO:1903561 - 0.00000000000000000000109 104.0
HKD2_k127_3865383_2 4Fe-4S double cluster binding domain K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000003763 69.0
HKD2_k127_3865383_3 - - - - 0.0000001392 62.0
HKD2_k127_3868828_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1212.0
HKD2_k127_386995_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 575.0
HKD2_k127_386995_1 transcription factor binding K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 469.0
HKD2_k127_386995_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002208 257.0
HKD2_k127_386995_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000003835 237.0
HKD2_k127_3874728_0 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008209 285.0
HKD2_k127_3874728_1 Belongs to the TtcA family K21947 - 2.8.1.15 0.000000000000000000000000001051 115.0
HKD2_k127_3874728_2 ThiS family K03154 - - 0.00004269 48.0
HKD2_k127_3880196_0 HMGL-like K01666 - 4.1.3.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003078 273.0
HKD2_k127_3880196_2 Caspase domain K03466 - - 0.00000000005267 73.0
HKD2_k127_3880196_3 Acyl transferase domain K00645 - 2.3.1.39 0.000003531 54.0
HKD2_k127_3881619_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 343.0
HKD2_k127_3881619_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000005269 126.0
HKD2_k127_388889_0 Transcriptional regulator of aromatic amino acids metabolism K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000003945 208.0
HKD2_k127_3892994_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000724 258.0
HKD2_k127_3892994_1 Protein of unknown function (DUF1638) - - - 0.00000000000000000000006114 102.0
HKD2_k127_3904090_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 4.245e-242 780.0
HKD2_k127_3904090_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 360.0
HKD2_k127_3904090_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001394 252.0
HKD2_k127_3904090_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000001897 211.0
HKD2_k127_3904090_4 acetyltransferase - - - 0.0000000000000000000000000000000000000000000006124 173.0
HKD2_k127_3904090_5 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000005705 140.0
HKD2_k127_3909463_0 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 416.0
HKD2_k127_3909463_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000003904 263.0
HKD2_k127_3909463_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000001134 181.0
HKD2_k127_3909463_3 pathogenesis K21471,K21687 - - 0.000000000000000004985 88.0
HKD2_k127_392337_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.595e-317 985.0
HKD2_k127_392337_1 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 445.0
HKD2_k127_392337_2 response regulator K03413,K07719 - - 0.00000000000000000000000008748 112.0
HKD2_k127_3926510_0 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 424.0
HKD2_k127_3926510_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 331.0
HKD2_k127_3926510_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000009097 159.0
HKD2_k127_3926510_3 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000724 157.0
HKD2_k127_3926510_4 CAAX protease self-immunity - - - 0.000000000000000000000902 106.0
HKD2_k127_3938597_0 Cellulase (glycosyl hydrolase family 5) K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 365.0
HKD2_k127_3944801_0 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 362.0
HKD2_k127_3944801_1 cellulose binding - - - 0.00000000000000000000000000000000000000000001839 174.0
HKD2_k127_3944801_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000001093 135.0
HKD2_k127_3960486_0 U4 snRNA binding K11127 - - 0.0000000000000000000000000000001404 138.0
HKD2_k127_3960486_1 serine-type endopeptidase activity K04771,K08372 - 3.4.21.107 0.0000000000006593 71.0
HKD2_k127_3989619_0 Streptomycin adenylyltransferase K05593 - - 0.000000000000000000000000000000000001886 141.0
HKD2_k127_3989619_1 - - - - 0.0000000000000000000000000000009789 126.0
HKD2_k127_3989619_2 - - - - 0.0000000000000000001099 94.0
HKD2_k127_3991038_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000005164 126.0
HKD2_k127_3991038_1 Involved in the tonB-independent uptake of proteins K01771 - 4.6.1.13 0.00000000427 65.0
HKD2_k127_400315_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000006356 207.0
HKD2_k127_400315_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000318 189.0
HKD2_k127_4046007_0 GMC oxidoreductase K03333 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016614,GO:0016899,GO:0016995,GO:0044419,GO:0051704,GO:0055114 1.1.3.6 3.106e-228 719.0
HKD2_k127_4046007_1 Aldehyde dehydrogenase family K00135 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.2.1.16,1.2.1.20,1.2.1.79 0.0002559 46.0
HKD2_k127_4059375_0 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 370.0
HKD2_k127_4059375_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000009563 120.0
HKD2_k127_4079175_0 ABC transporter, ATP-binding protein K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005732 274.0
HKD2_k127_4079175_1 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000342 260.0
HKD2_k127_4079175_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000003883 226.0
HKD2_k127_4079175_3 CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000001411 208.0
HKD2_k127_4118095_0 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000197 168.0
HKD2_k127_4118095_1 Metallo-beta-lactamase superfamily - - - 0.000000008624 66.0
HKD2_k127_4118259_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.613e-207 660.0
HKD2_k127_4118259_1 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001148 284.0
HKD2_k127_4118259_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005855 271.0
HKD2_k127_4118259_3 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000001766 262.0
HKD2_k127_4118259_4 Inorganic pyrophosphatase - - - 0.0000000000000000000000000000000009229 144.0
HKD2_k127_4120309_0 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000005076 171.0
HKD2_k127_4120309_1 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000004592 154.0
HKD2_k127_4120309_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000009043 136.0
HKD2_k127_4120309_3 Male sterility protein K12454 - 5.1.3.10 0.00000005311 56.0
HKD2_k127_4122361_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008348 274.0
HKD2_k127_4122361_1 F420H(2)-dependent quinone reductase - - - 0.000000000000000000006122 100.0
HKD2_k127_4122361_2 transmembrane transport K01992,K09696 - - 0.0000235 53.0
HKD2_k127_4131452_0 - - - - 0.00000000000000000000000000000000000000000000000000009996 193.0
HKD2_k127_4131452_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000000000000000000004492 183.0
HKD2_k127_4133082_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.702e-218 695.0
HKD2_k127_4133082_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
HKD2_k127_4133082_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000004045 114.0
HKD2_k127_4133082_3 RDD family - - - 0.0000258 55.0
HKD2_k127_4133699_0 elongation factor Tu domain 2 protein K02355 - - 3.467e-308 957.0
HKD2_k127_4136447_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 332.0
HKD2_k127_4136447_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 309.0
HKD2_k127_4136447_2 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000004194 169.0
HKD2_k127_4140218_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 460.0
HKD2_k127_4144197_0 Homoserine O-succinyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 396.0
HKD2_k127_4144197_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 324.0
HKD2_k127_4147855_0 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 361.0
HKD2_k127_4147855_1 Methicillin resistance protein K05363,K18354 - 2.3.2.10 0.00006846 54.0
HKD2_k127_4147892_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 404.0
HKD2_k127_4147892_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005426 283.0
HKD2_k127_4147892_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002055 284.0
HKD2_k127_4147892_3 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000002088 263.0
HKD2_k127_4147892_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.000000000000000000000000000000000000000000000000000001051 209.0
HKD2_k127_4151441_0 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 584.0
HKD2_k127_4151441_1 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 353.0
HKD2_k127_4151441_2 Oxidoreductase - - - 0.0000000000000000000000000009842 125.0
HKD2_k127_4162612_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001239 246.0
HKD2_k127_4162612_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000001793 112.0
HKD2_k127_4165565_0 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 305.0
HKD2_k127_4165565_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000003321 126.0
HKD2_k127_4177515_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1036.0
HKD2_k127_4191115_0 alpha-galactosidase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 586.0
HKD2_k127_4192627_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 398.0
HKD2_k127_4192627_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000007533 156.0
HKD2_k127_4192627_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000006665 83.0
HKD2_k127_4192627_3 PD-(D/E)XK nuclease superfamily - - - 0.000001286 50.0
HKD2_k127_4207803_0 Phosphoribosylformylglycinamidine cyclo-ligase K11788 GO:0003674,GO:0003824,GO:0004637,GO:0004641,GO:0006139,GO:0006144,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046112,GO:0046148,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 312.0
HKD2_k127_4207803_1 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002873 265.0
HKD2_k127_4222616_0 enterobactin catabolic process K07214 - - 0.000000000000001337 85.0
HKD2_k127_4222616_1 Putative esterase - - - 0.00000000000002125 85.0
HKD2_k127_4223609_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 609.0
HKD2_k127_4223609_1 aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 516.0
HKD2_k127_4223609_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 387.0
HKD2_k127_4223609_3 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 316.0
HKD2_k127_4223609_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000003999 89.0
HKD2_k127_4223609_5 - - - - 0.0001993 51.0
HKD2_k127_4223906_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 4.788e-258 822.0
HKD2_k127_4223906_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000005627 102.0
HKD2_k127_4223906_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000003766 71.0
HKD2_k127_4229818_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 308.0
HKD2_k127_4229818_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009203 262.0
HKD2_k127_4238159_0 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 329.0
HKD2_k127_4238159_1 Helicase conserved C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 256.0
HKD2_k127_4238159_2 PFAM diacylglycerol kinase catalytic region - - - 0.0000000000000000000000000002917 119.0
HKD2_k127_4239611_0 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 320.0
HKD2_k127_4239611_1 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000001356 59.0
HKD2_k127_4242264_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 468.0
HKD2_k127_4242264_1 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 445.0
HKD2_k127_4242264_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000004542 201.0
HKD2_k127_4242264_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000002232 102.0
HKD2_k127_4242264_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000001263 58.0
HKD2_k127_4252141_0 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 336.0
HKD2_k127_4252141_1 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004032 268.0
HKD2_k127_4252141_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000003482 211.0
HKD2_k127_4252141_3 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000947 165.0
HKD2_k127_4252141_4 Protein of unknown function (DUF1653) K03574 - 3.6.1.55 0.0000000000000000000000000000000006372 134.0
HKD2_k127_4252141_5 HMGL-like K02594 - 2.3.3.14 0.0000000000000000000001907 101.0
HKD2_k127_4260462_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 395.0
HKD2_k127_4260462_1 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 380.0
HKD2_k127_4260462_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000134 282.0
HKD2_k127_4260462_3 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000000009137 220.0
HKD2_k127_4260462_4 oligosaccharyl transferase activity - - - 0.0000005075 63.0
HKD2_k127_4263537_0 PFAM Acetyl-CoA hydrolase transferase - - - 2.322e-204 653.0
HKD2_k127_4263537_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 322.0
HKD2_k127_4274118_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000001975 153.0
HKD2_k127_4296636_0 - - - - 0.000000000000000002649 96.0
HKD2_k127_4296970_0 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 316.0
HKD2_k127_4296970_1 O-methyltransferase activity K00545 - 2.1.1.6 0.000000000000000000000000000000000000000000000000000000000002074 219.0
HKD2_k127_4296970_2 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000003529 68.0
HKD2_k127_432935_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 1.458e-214 680.0
HKD2_k127_432935_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 519.0
HKD2_k127_432935_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000001683 229.0
HKD2_k127_432935_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000003654 220.0
HKD2_k127_432935_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000005027 230.0
HKD2_k127_432935_5 Rhomboid family - GO:0000003,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004842,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009507,GO:0009526,GO:0009536,GO:0009653,GO:0009791,GO:0009826,GO:0009888,GO:0009941,GO:0009987,GO:0010026,GO:0010154,GO:0016020,GO:0016043,GO:0016049,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0022412,GO:0022414,GO:0030154,GO:0031090,GO:0031967,GO:0031969,GO:0031975,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0036211,GO:0040007,GO:0042170,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0048316,GO:0048468,GO:0048589,GO:0048608,GO:0048731,GO:0048856,GO:0048869,GO:0060560,GO:0061458,GO:0070647,GO:0071704,GO:0071840,GO:0090376,GO:0090378,GO:0090558,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000001448 170.0
HKD2_k127_432935_6 Putative regulatory protein - - - 0.000000000000000000000000000000000000006356 149.0
HKD2_k127_432935_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000002653 148.0
HKD2_k127_4332323_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 380.0
HKD2_k127_4332323_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000002325 236.0
HKD2_k127_4332474_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 357.0
HKD2_k127_4336657_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 400.0
HKD2_k127_4336657_1 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000005268 93.0
HKD2_k127_4336806_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005492 268.0
HKD2_k127_4336806_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001024 205.0
HKD2_k127_4336806_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008789 201.0
HKD2_k127_4336806_3 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000003896 113.0
HKD2_k127_4336806_4 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001274 94.0
HKD2_k127_434732_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 320.0
HKD2_k127_434732_1 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000001885 183.0
HKD2_k127_4359564_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000306 222.0
HKD2_k127_4367042_0 transferase activity, transferring glycosyl groups K00752,K14666 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006082,GO:0006807,GO:0007155,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016757,GO:0016758,GO:0019752,GO:0022607,GO:0022610,GO:0030198,GO:0030203,GO:0030212,GO:0030213,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0042710,GO:0043062,GO:0043170,GO:0043436,GO:0044010,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044425,GO:0044459,GO:0044464,GO:0044764,GO:0045226,GO:0046379,GO:0046394,GO:0050501,GO:0051704,GO:0071704,GO:0071840,GO:0071944,GO:0085029,GO:0090605,GO:0090609,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903510 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 298.0
HKD2_k127_4372161_0 ABC transporter transmembrane region K06147 - - 6.78e-236 747.0
HKD2_k127_4383240_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000002886 173.0
HKD2_k127_4383240_1 COG1361 S-layer domain - - - 0.00005183 54.0
HKD2_k127_4384838_0 Family 4 glycosyl hydrolase K01222 - 3.2.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 491.0
HKD2_k127_4384838_1 SIS domain K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 317.0
HKD2_k127_4384838_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002854 244.0
HKD2_k127_4384838_3 YdjC-like protein K03478 - 3.5.1.105 0.0000000004143 63.0
HKD2_k127_43907_0 signal transduction histidine kinase K11623 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000001803 239.0
HKD2_k127_43907_1 - - - - 0.00000000000000000006218 104.0
HKD2_k127_4422737_0 PFAM Glycosyl hydrolase family 1 K01223,K05350 - 3.2.1.21,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 418.0
HKD2_k127_4422737_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000001579 81.0
HKD2_k127_4422737_2 Domain of unknown function (DUF1508) K09946 - - 0.00000000000008966 73.0
HKD2_k127_4429501_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000104 186.0
HKD2_k127_4429501_1 DNA-binding transcription factor activity - - - 0.0000000000000000000000000004629 117.0
HKD2_k127_4458710_0 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 347.0
HKD2_k127_4458710_1 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000001896 149.0
HKD2_k127_4458710_2 zinc-ribbon domain - - - 0.00000817 51.0
HKD2_k127_4462240_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 424.0
HKD2_k127_4462240_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000474 264.0
HKD2_k127_4462240_2 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000134 247.0
HKD2_k127_4462240_3 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000008258 193.0
HKD2_k127_4478096_0 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 370.0
HKD2_k127_4478096_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000001874 91.0
HKD2_k127_4483271_0 ATPase (P-type) K01535 - 3.6.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 377.0
HKD2_k127_4483271_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006753,GO:0006760,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008864,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009256,GO:0009257,GO:0009259,GO:0009260,GO:0009396,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 333.0
HKD2_k127_4483271_2 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 295.0
HKD2_k127_4483271_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000001496 161.0
HKD2_k127_4483271_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000001433 168.0
HKD2_k127_4483271_5 Domain of unknown function (DU1801) - - - 0.00000000000000001466 88.0
HKD2_k127_4483307_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000119 273.0
HKD2_k127_4483307_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000002957 195.0
HKD2_k127_4483307_2 response to heat K03668,K09914 - - 0.00000000000004863 83.0
HKD2_k127_4509310_0 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 484.0
HKD2_k127_4509310_1 Transglutaminase-like superfamily - - - 0.0000000000000000003671 98.0
HKD2_k127_4510760_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 385.0
HKD2_k127_4510760_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00006128 51.0
HKD2_k127_4539590_0 ABC transporter K02056,K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 610.0
HKD2_k127_4539590_1 Periplasmic binding protein-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 332.0
HKD2_k127_4539590_2 Periplasmic binding protein-like domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001175 274.0
HKD2_k127_4541819_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000836 252.0
HKD2_k127_4541819_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000001007 202.0
HKD2_k127_4541819_2 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000002631 142.0
HKD2_k127_4541819_3 ubiE/COQ5 methyltransferase family - - - 0.0002068 51.0
HKD2_k127_4543563_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000001259 194.0
HKD2_k127_454489_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 298.0
HKD2_k127_454489_1 ATPases associated with a variety of cellular activities K10831 - 3.6.3.36 0.0000008289 61.0
HKD2_k127_454536_0 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 557.0
HKD2_k127_454536_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 356.0
HKD2_k127_454536_2 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000005437 205.0
HKD2_k127_4545784_0 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000002086 205.0
HKD2_k127_4545784_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000004361 103.0
HKD2_k127_4545784_2 Kdo2-lipid A biosynthetic process K02517,K20543,K22311 - 2.3.1.241,2.3.1.265 0.00000000009927 67.0
HKD2_k127_4553550_0 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 324.0
HKD2_k127_4553550_1 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000003743 210.0
HKD2_k127_4558605_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 7.619e-218 688.0
HKD2_k127_4558605_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 302.0
HKD2_k127_4558605_2 HAD-hyrolase-like K07025 - - 0.00000000000000000000000000001114 124.0
HKD2_k127_4558605_3 Cold shock K03704 - - 0.00000000000000004616 83.0
HKD2_k127_4558605_4 Tetratricopeptide repeat - - - 0.00000001577 66.0
HKD2_k127_4559502_0 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 366.0
HKD2_k127_4559880_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000185 249.0
HKD2_k127_4559880_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000002917 186.0
HKD2_k127_4559880_2 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000001761 137.0
HKD2_k127_4567665_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001113 258.0
HKD2_k127_4567665_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000495 126.0
HKD2_k127_4567665_2 - - - - 0.00000000000000000000000007031 118.0
HKD2_k127_4568859_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000003185 266.0
HKD2_k127_4568859_1 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.00003726 47.0
HKD2_k127_4572555_0 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 315.0
HKD2_k127_4572555_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000004013 72.0
HKD2_k127_4590602_0 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
HKD2_k127_4590602_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000003157 180.0
HKD2_k127_4605941_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000005823 60.0
HKD2_k127_4605941_1 Proteins of 100 residues with WXG - - - 0.0002229 48.0
HKD2_k127_4611774_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000001494 219.0
HKD2_k127_4616928_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 602.0
HKD2_k127_4616928_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000001312 64.0
HKD2_k127_4619657_0 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 428.0
HKD2_k127_4619657_1 BioY family K03523 - - 0.000000000000000000003323 100.0
HKD2_k127_4619657_2 Catalyzes the reversible conversion of 5-aminoimidazole ribonucleotide (AIR) and CO(2) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000103 61.0
HKD2_k127_4624647_0 Cupin domain - - - 0.00000005923 55.0
HKD2_k127_4624647_1 - - - - 0.000006916 54.0
HKD2_k127_4638789_0 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002658 268.0
HKD2_k127_4638789_1 N-Acetylmuramoyl-L-alanine amidase K01207,K01447,K11066 - 3.2.1.52,3.5.1.28 0.0000000000000000000000000000000000000000003418 176.0
HKD2_k127_4638789_2 polysaccharide deacetylase - - - 0.00000000000000000004184 104.0
HKD2_k127_4638789_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0007961 44.0
HKD2_k127_463966_0 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000005257 218.0
HKD2_k127_463966_1 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.0000000000000003013 85.0
HKD2_k127_4643472_0 Protein of unknown function (DUF429) - - - 0.0000001398 62.0
HKD2_k127_4659404_0 hexokinase K00844 - 2.7.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 386.0
HKD2_k127_4659404_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000002895 96.0
HKD2_k127_4670175_0 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002455 263.0
HKD2_k127_4670175_1 phosphorelay sensor kinase activity K01768,K02482,K02584,K07673,K10819 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000002568 136.0
HKD2_k127_4670175_2 PAS fold - - - 0.0004246 53.0
HKD2_k127_4683543_0 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 360.0
HKD2_k127_4683543_1 PFAM binding-protein-dependent transport systems inner membrane component K10119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
HKD2_k127_4683543_2 Extracellular solute-binding protein K02027,K10117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 332.0
HKD2_k127_4683543_3 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 286.0
HKD2_k127_4696871_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 8.281e-272 855.0
HKD2_k127_4696871_1 Involved in the tonB-independent uptake of proteins K01771 - 4.6.1.13 0.000000000000000000000000000000000000000001103 175.0
HKD2_k127_4696871_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000007221 142.0
HKD2_k127_4745266_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000004373 132.0
HKD2_k127_4745266_1 -O-antigen K02847,K13009 - - 0.00001821 57.0
HKD2_k127_4745266_2 MreB/Mbl protein K04043 - - 0.0000411 52.0
HKD2_k127_4747204_0 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 329.0
HKD2_k127_4748282_0 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 548.0
HKD2_k127_4748282_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 - - 0.00000000000000000000000000000000002749 141.0
HKD2_k127_4748282_2 COG1419 Flagellar GTP-binding protein K02404 - - 0.000000000000000001655 91.0
HKD2_k127_4748282_3 Global regulator protein family K03563 - - 0.00000000000001046 77.0
HKD2_k127_4748282_4 - - - - 0.0002282 50.0
HKD2_k127_4750785_0 FR47-like protein - - - 0.0000000000000000000000000000000000000000001959 166.0
HKD2_k127_4755570_0 Glyco_18 K01183 - 3.2.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 340.0
HKD2_k127_4765172_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004211 275.0
HKD2_k127_4765172_1 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000001192 213.0
HKD2_k127_4765172_2 Pkd domain containing protein - - - 0.00000000000000000000000000000000000004497 164.0
HKD2_k127_4765172_3 - - - - 0.000000000000000000000000005757 119.0
HKD2_k127_4765172_4 Regulatory protein, FmdB family - - - 0.0000000000000000000000001066 110.0
HKD2_k127_4765172_5 Domain of unknown function DUF11 - - - 0.00007676 56.0
HKD2_k127_4766135_0 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 340.0
HKD2_k127_4766135_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000007517 181.0
HKD2_k127_4775698_0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000001467 240.0
HKD2_k127_4775698_1 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.00000000000000000000000000000000000000000000000001369 188.0
HKD2_k127_4775698_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000007075 166.0
HKD2_k127_4775698_3 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000009766 86.0
HKD2_k127_4775698_4 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0009507,GO:0009536,GO:0015934,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000005531 64.0
HKD2_k127_4809887_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000007331 117.0
HKD2_k127_4823176_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000002607 178.0
HKD2_k127_4823176_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000271 172.0
HKD2_k127_4827487_0 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10545,K10548 - 3.6.3.17 1.448e-211 667.0
HKD2_k127_4827487_1 Periplasmic binding protein domain K10543,K10546 - - 0.00001929 46.0
HKD2_k127_4831789_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 473.0
HKD2_k127_4831789_1 transferase activity, transferring glycosyl groups K21369 - 2.4.1.270 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 413.0
HKD2_k127_4831789_2 Sucrose phosphorylase related protein K00690 - 2.4.1.7 0.000000001499 64.0
HKD2_k127_4842958_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 499.0
HKD2_k127_4842958_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001156 252.0
HKD2_k127_4842958_2 His Kinase A (phosphoacceptor) domain K12132 - 2.7.11.1 0.000000000000000000000000000000000003383 160.0
HKD2_k127_4845414_0 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003123 290.0
HKD2_k127_485821_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 436.0
HKD2_k127_485821_1 Vitamin K epoxide reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000003195 232.0
HKD2_k127_485821_2 DinB family - - - 0.0000000000000000000000000000000000000000000004054 173.0
HKD2_k127_485821_3 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000006022 154.0
HKD2_k127_487555_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 298.0
HKD2_k127_487555_1 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 299.0
HKD2_k127_4881511_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
HKD2_k127_4881511_1 Methyltransferase FkbM domain - - - 0.0001785 51.0
HKD2_k127_488659_0 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000003935 147.0
HKD2_k127_488659_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000006714 64.0
HKD2_k127_4894790_0 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000756 222.0
HKD2_k127_4894790_1 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000001809 198.0
HKD2_k127_4909397_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001125 167.0
HKD2_k127_4909397_1 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000005491 154.0
HKD2_k127_4909397_2 amino acid K14052 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008324,GO:0008519,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015101,GO:0015203,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015489,GO:0015672,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0033554,GO:0034220,GO:0034641,GO:0040011,GO:0042402,GO:0044106,GO:0044237,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051234,GO:0051674,GO:0051716,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072488,GO:0097164,GO:0098655,GO:0098660,GO:0098662,GO:1901564,GO:1901565,GO:1901575,GO:1902047,GO:1902600 - 0.00003569 49.0
HKD2_k127_4916276_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000009476 119.0
HKD2_k127_4916276_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000001409 74.0
HKD2_k127_4916614_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 415.0
HKD2_k127_4916614_1 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001873 285.0
HKD2_k127_4916614_2 Domain of unknown function (DUF4349) - - - 0.000000000000000000000001265 118.0
HKD2_k127_4916614_3 acetyltransferase - - - 0.000000000000000000003958 95.0
HKD2_k127_492091_0 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000452 258.0
HKD2_k127_492091_1 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.00000000000000000000000000000000000743 151.0
HKD2_k127_492091_2 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000002867 131.0
HKD2_k127_4921354_0 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 561.0
HKD2_k127_4921354_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 362.0
HKD2_k127_4922641_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000000104 247.0
HKD2_k127_4922641_1 cellulose binding - - - 0.0000000000000000000201 104.0
HKD2_k127_4922641_2 in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 0.0000000001636 63.0
HKD2_k127_4943772_0 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002552 244.0
HKD2_k127_4943772_1 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000967 210.0
HKD2_k127_4943772_2 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000008501 208.0
HKD2_k127_4943772_3 Phospholipid methyltransferase - - - 0.0000000000004616 82.0
HKD2_k127_4949462_0 Transcriptional regulator K07721 - - 0.00000000000003038 74.0
HKD2_k127_4949462_1 - - - - 0.0003295 51.0
HKD2_k127_4958458_0 endo-1,4-beta-xylanase activity K01181 GO:0005575,GO:0005576 3.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 451.0
HKD2_k127_4958458_1 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000003071 226.0
HKD2_k127_4958458_2 - - - - 0.00000000000000000000000000000001361 133.0
HKD2_k127_4958458_4 Methyltransferase type 11 - - - 0.00007083 53.0
HKD2_k127_5012508_0 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000008184 234.0
HKD2_k127_5025979_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000001768 133.0
HKD2_k127_5027012_0 Histidine kinase - - - 0.00000000000000000000000000000000000002116 167.0
HKD2_k127_5027012_1 - - - - 0.000000001425 72.0
HKD2_k127_5093427_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 315.0
HKD2_k127_5093427_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 304.0
HKD2_k127_5093427_2 Flagellar protein YcgR - - - 0.00000000000000001102 92.0
HKD2_k127_5093427_3 sterol carrier protein - - - 0.00000000000000001838 85.0
HKD2_k127_5098241_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 3.046e-208 659.0
HKD2_k127_5098241_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000001957 145.0
HKD2_k127_5109588_0 MacB-like periplasmic core domain K02004 - - 1.419e-229 730.0
HKD2_k127_5109588_1 ABC transporter K02003 - - 0.000000000000000000000000000000002448 132.0
HKD2_k127_510975_0 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000006904 271.0
HKD2_k127_5133736_0 Aconitase family (aconitate hydratase) K01703,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 324.0
HKD2_k127_514744_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000001281 121.0
HKD2_k127_514744_1 - - - - 0.00000000000000000006532 94.0
HKD2_k127_514744_2 serine threonine protein kinase - - - 0.00000000002363 74.0
HKD2_k127_514744_3 gas vesicle protein - - - 0.00000002798 64.0
HKD2_k127_514744_4 domain, Protein - - - 0.00000005973 63.0
HKD2_k127_514744_5 Bacterial SH3 domain - - - 0.0000001542 64.0
HKD2_k127_5157385_0 Bacterial membrane protein, YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000006392 244.0
HKD2_k127_5157385_1 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000003154 168.0
HKD2_k127_5161942_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 316.0
HKD2_k127_5161942_1 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000004108 172.0
HKD2_k127_5161942_2 PBS lyase HEAT-like repeat - - - 0.0000000000000001223 88.0
HKD2_k127_5161942_3 Belongs to the peptidase M50B family - - - 0.00001476 48.0
HKD2_k127_5172123_0 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000012 222.0
HKD2_k127_5172123_1 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000299 217.0
HKD2_k127_5184028_0 PFAM regulator of chromosome condensation, RCC1 - - - 1.146e-216 696.0
HKD2_k127_5184028_1 PFAM major facilitator superfamily MFS_1 K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 326.0
HKD2_k127_51927_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.305e-268 839.0
HKD2_k127_51927_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000001036 141.0
HKD2_k127_5202035_0 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 426.0
HKD2_k127_5202035_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 306.0
HKD2_k127_5202035_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003718 284.0
HKD2_k127_5202035_3 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.00000000000000000000000000000000000000002966 154.0
HKD2_k127_5202035_4 Polysaccharide deacetylase - - - 0.0000000000000000000000000000001871 131.0
HKD2_k127_5218307_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000006857 180.0
HKD2_k127_5225108_0 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 0.00000000000009945 84.0
HKD2_k127_5260754_0 Secretion system protein K02283 - - 0.0000000002273 69.0
HKD2_k127_5260754_1 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00009655 52.0
HKD2_k127_5280877_0 aminopeptidase activity K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 467.0
HKD2_k127_5280877_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 348.0
HKD2_k127_5280877_2 Beta-lactamase superfamily domain - - - 0.00000009712 63.0
HKD2_k127_5284417_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002098 270.0
HKD2_k127_5284417_1 AAA ATPase - - - 0.0000000000000334 85.0
HKD2_k127_5284417_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000006207 72.0
HKD2_k127_5288726_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 375.0
HKD2_k127_5288726_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 303.0
HKD2_k127_5288726_2 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000368 191.0
HKD2_k127_5288726_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000001275 162.0
HKD2_k127_5288726_4 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000002271 156.0
HKD2_k127_5345191_0 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 324.0
HKD2_k127_5345191_1 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000000000000000002452 221.0
HKD2_k127_5356794_0 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 503.0
HKD2_k127_5356794_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
HKD2_k127_5356794_2 - - - - 0.000000000000000000000000000007229 122.0
HKD2_k127_5364853_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000001155 175.0
HKD2_k127_5364853_1 methyltransferase - - - 0.0000000000000000000000000000000000002726 150.0
HKD2_k127_5364853_2 Peptidase M56 - - - 0.000000000000000000000000000003379 126.0
HKD2_k127_5374730_0 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.00000000000000000000000000000000000003208 148.0
HKD2_k127_5374730_1 WHG domain - - - 0.00000000000000001224 91.0
HKD2_k127_5407617_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 499.0
HKD2_k127_5407617_1 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006359 260.0
HKD2_k127_5410978_0 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 393.0
HKD2_k127_5411034_0 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000000000000002973 169.0
HKD2_k127_5411034_1 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.000000000000000000000000000000000000001286 156.0
HKD2_k127_5430374_0 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 321.0
HKD2_k127_5430374_1 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 304.0
HKD2_k127_5430374_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000003109 191.0
HKD2_k127_5446722_0 Histidine kinase K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000001714 223.0
HKD2_k127_5446722_1 cellulose-binding family II - - - 0.0000000000000000000000000000000000005575 143.0
HKD2_k127_5454986_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000006755 178.0
HKD2_k127_5454986_1 histidine kinase A domain protein - - - 0.000000000000000000000000000005887 137.0
HKD2_k127_5467382_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000001709 186.0
HKD2_k127_5467382_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000002595 143.0
HKD2_k127_5473336_0 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005919 280.0
HKD2_k127_5473336_1 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000001032 225.0
HKD2_k127_5506190_0 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000003067 214.0
HKD2_k127_5506190_1 ATP hydrolysis coupled proton transport - - - 0.000000457 55.0
HKD2_k127_5522475_0 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008736 253.0
HKD2_k127_5522475_1 HAD-superfamily hydrolase subfamily IA, variant 3 K01838,K19270 GO:0000287,GO:0003674,GO:0003824,GO:0003850,GO:0004346,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050084,GO:0050286,GO:0050308,GO:0050309 3.1.3.23,5.4.2.6 0.0000000000000000000000000000000000000000000000000000009782 203.0
HKD2_k127_5522475_2 Glycosyl transferase family 2 - - - 0.000000000000003202 77.0
HKD2_k127_552684_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001101 278.0
HKD2_k127_5528450_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 308.0
HKD2_k127_5528450_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000008607 250.0
HKD2_k127_5528450_2 transferase activity, transferring glycosyl groups K21011,K21012 - - 0.0000000000000000000000000000000000000000000000000000000000001732 224.0
HKD2_k127_5528450_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000002203 177.0
HKD2_k127_5546140_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 469.0
HKD2_k127_5548224_0 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 368.0
HKD2_k127_5548224_1 Nitroreductase family - - - 0.00000000000000000000000000000000000001969 149.0
HKD2_k127_5548224_2 Protein of unknown function (DUF4013) - - - 0.000000000000000001341 94.0
HKD2_k127_5548224_3 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000006068 75.0
HKD2_k127_5548279_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 562.0
HKD2_k127_5548279_1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K04708 - 1.1.1.102 0.0000000000000000000000000000000000000000000000000000000001066 219.0
HKD2_k127_5548279_2 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000001324 140.0
HKD2_k127_556022_0 Putative TM nitroreductase - - - 0.0000000000000000000000000000001673 129.0
HKD2_k127_556022_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000007289 124.0
HKD2_k127_556022_2 L-glyceraldehyde 3-phosphate reductase K19265 - - 0.000000000000000000000000000815 114.0
HKD2_k127_556022_3 Pyrrolo-quinoline quinone - - - 0.00006508 55.0
HKD2_k127_556484_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 444.0
HKD2_k127_556484_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 340.0
HKD2_k127_556484_2 Esterase PHB depolymerase K03932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001384 268.0
HKD2_k127_556484_3 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000007238 241.0
HKD2_k127_556484_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000003624 190.0
HKD2_k127_556484_5 Putative membrane peptidase family (DUF2324) - - - 0.000000000000000000000000000000000000000000000000002819 194.0
HKD2_k127_556484_6 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000414 185.0
HKD2_k127_556484_7 xyloglucan:xyloglucosyl transferase activity - - - 0.000000005963 58.0
HKD2_k127_5580395_0 glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 504.0
HKD2_k127_5580395_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000002672 218.0
HKD2_k127_5580395_2 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000003255 134.0
HKD2_k127_5585623_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000005315 233.0
HKD2_k127_5585623_1 nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000000000000000000000000000000000000004897 186.0
HKD2_k127_5585623_2 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000002001 151.0
HKD2_k127_559652_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 315.0
HKD2_k127_559652_1 Belongs to the peptidase S51 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001886 301.0
HKD2_k127_559652_2 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000009043 207.0
HKD2_k127_5599485_0 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 396.0
HKD2_k127_5599485_1 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 328.0
HKD2_k127_5622933_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000002376 168.0
HKD2_k127_5622933_1 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000001191 164.0
HKD2_k127_5622933_2 Protein of unknown function (DUF3467) - - - 0.000000000000000001209 90.0
HKD2_k127_562522_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 9.446e-194 611.0
HKD2_k127_562522_1 maltose binding K02027,K15770 - - 0.00000000000000000000000000000000000000001133 169.0
HKD2_k127_5655639_0 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000000000000000000000000000000000006223 220.0
HKD2_k127_5668361_0 Histidine kinase K07777,K19661,K21405 - 2.7.13.3 0.000000000000000000000000000000000000000000003109 170.0
HKD2_k127_5668361_1 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000001857 113.0
HKD2_k127_5668361_2 YHS domain - - - 0.00000000000000004007 83.0
HKD2_k127_5668361_3 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.0000001749 55.0
HKD2_k127_5688695_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 429.0
HKD2_k127_5692913_0 Staphylococcal nuclease homologues K01174,K07038 - 3.1.31.1 0.000000000000000000000000000000000000000002767 166.0
HKD2_k127_5699403_0 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000009975 181.0
HKD2_k127_5699403_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000001205 103.0
HKD2_k127_5699403_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000006491 61.0
HKD2_k127_5705220_0 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000436 160.0
HKD2_k127_5706041_0 PFAM ABC transporter related K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 338.0
HKD2_k127_5706041_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 340.0
HKD2_k127_5706041_2 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 305.0
HKD2_k127_5706041_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 323.0
HKD2_k127_5706041_4 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000641 280.0
HKD2_k127_5706041_5 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004336 237.0
HKD2_k127_5706041_6 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000002994 119.0
HKD2_k127_5706041_7 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000003764 108.0
HKD2_k127_5706041_8 Cupin domain - - - 0.000000000001294 68.0
HKD2_k127_5712767_0 PFAM type II secretion system protein E K02283 - - 2.634e-209 659.0
HKD2_k127_5712767_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 364.0
HKD2_k127_5712767_2 PFAM type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 325.0
HKD2_k127_5712767_3 PFAM type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002491 258.0
HKD2_k127_5712767_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000001198 147.0
HKD2_k127_5712767_5 competence protein - - - 0.00000000000000000000000000000000000312 151.0
HKD2_k127_5715287_0 alginic acid biosynthetic process - - - 0.0009232 49.0
HKD2_k127_5716692_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.913e-295 919.0
HKD2_k127_5716692_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit K01546 - 3.6.3.12 0.00002507 46.0
HKD2_k127_5718262_0 Glycosyl hydrolases family 31 K01811 - 3.2.1.177 6.524e-245 775.0
HKD2_k127_5718512_0 Glycosyl hydrolase 36 superfamily, catalytic domain K00702 - 2.4.1.20 4.741e-271 854.0
HKD2_k127_5735506_0 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000002822 85.0
HKD2_k127_5735506_1 GAF domain - - - 0.0000000000004801 72.0
HKD2_k127_5739890_0 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000006377 236.0
HKD2_k127_5739890_1 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000002766 96.0
HKD2_k127_5739890_2 Protein of unknown function (DUF1761) - - - 0.0000002176 59.0
HKD2_k127_5748118_0 methyltransferase activity - - - 0.000000000000000000000000000000001513 139.0
HKD2_k127_5748118_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000001388 98.0
HKD2_k127_5755804_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 512.0
HKD2_k127_5755804_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005826 257.0
HKD2_k127_5755804_2 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009748 248.0
HKD2_k127_5755804_3 peptidase activity - - - 0.00000000000000000000000000000000000000004308 164.0
HKD2_k127_5755804_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000305 121.0
HKD2_k127_5756406_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 432.0
HKD2_k127_5756406_1 Double zinc ribbon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 323.0
HKD2_k127_5756406_2 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000005313 182.0
HKD2_k127_5756406_3 acetyltransferase - - - 0.00000000000000000000000000000000002171 141.0
HKD2_k127_5756406_4 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000008297 135.0
HKD2_k127_5767741_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 416.0
HKD2_k127_5767741_1 serine threonine protein kinase - - - 0.00002591 50.0
HKD2_k127_5772708_0 Catalyzes the release of L-lysine from LysW -gamma-L- lysine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 371.0
HKD2_k127_5772708_1 Pkd domain containing protein - - - 0.000000000000000001559 88.0
HKD2_k127_5772708_2 peptidase - - - 0.0001368 47.0
HKD2_k127_5772874_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000001288 221.0
HKD2_k127_5776147_0 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000002039 218.0
HKD2_k127_5776147_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000007721 173.0
HKD2_k127_5776147_2 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.000000000000000003423 91.0
HKD2_k127_5822975_0 PFAM major facilitator superfamily MFS_1 K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 414.0
HKD2_k127_5822975_1 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000008327 236.0
HKD2_k127_5822975_2 - - - - 0.000000000000000000000000000136 117.0
HKD2_k127_5824758_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 493.0
HKD2_k127_5824758_1 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000009476 204.0
HKD2_k127_5824758_2 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000001708 70.0
HKD2_k127_5838396_0 Ion transport 2 domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001146 250.0
HKD2_k127_5838396_1 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000001045 166.0
HKD2_k127_5838396_2 - - - - 0.000000000001889 71.0
HKD2_k127_5838396_3 Transglycosylase SLT domain - - - 0.000007395 57.0
HKD2_k127_5857825_0 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000025 200.0
HKD2_k127_5857825_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000007693 181.0
HKD2_k127_5864108_0 UbiA prenyltransferase family K20616 - - 0.000000000003606 78.0
HKD2_k127_5868607_0 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 356.0
HKD2_k127_5868607_1 PFAM extracellular solute-binding protein family 1 K02040 - - 0.00000000000000000001484 101.0
HKD2_k127_5874737_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000003028 185.0
HKD2_k127_5874737_1 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000000002416 146.0
HKD2_k127_5874737_2 PFAM Bacterial regulatory protein, arsR family K21903 - - 0.00000000000000000004086 93.0
HKD2_k127_5874989_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 306.0
HKD2_k127_5874989_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001625 276.0
HKD2_k127_5874989_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000008523 192.0
HKD2_k127_5876949_0 PFAM glycosyl transferase, family 51 - - - 0.0 1090.0
HKD2_k127_5876949_1 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000007785 240.0
HKD2_k127_5876949_2 MaoC like domain - - - 0.0000000000000000000000000000000000000000000001231 174.0
HKD2_k127_5876949_3 PFAM Bacterial regulatory protein, arsR family K03892 - - 0.000000002223 60.0
HKD2_k127_5876949_4 Lysin motif - - - 0.00000001492 64.0
HKD2_k127_5881990_0 PFAM Spore coat protein CotH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 632.0
HKD2_k127_5881990_1 IMP cyclohydrolase activity K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000002072 250.0
HKD2_k127_5881990_2 Domain of unknown function (DUF4956) - - - 0.00000000000000000000000000000000000000000000000000000005363 203.0
HKD2_k127_5881990_3 VTC domain - - - 0.0000000000000000000000000000000000000000000000008097 183.0
HKD2_k127_5881990_4 - - - - 0.00000000000000000003053 99.0
HKD2_k127_5885847_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 294.0
HKD2_k127_5885847_1 ABC-type sugar transport system periplasmic component K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001596 269.0
HKD2_k127_5885847_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000003094 75.0
HKD2_k127_5893817_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 587.0
HKD2_k127_5900809_0 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 294.0
HKD2_k127_5900809_1 KR domain - - - 0.00000000000000000000000000002775 123.0
HKD2_k127_5903966_0 GAF domain - - - 0.0000000000000000000000000000000000000000000009854 181.0
HKD2_k127_5912572_0 metalloendopeptidase activity K11749,K16922 - - 0.000000000000000000000000009696 123.0
HKD2_k127_5947336_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 374.0
HKD2_k127_5947336_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000001239 224.0
HKD2_k127_5947336_2 Putative neutral zinc metallopeptidase K06973 - - 0.00000000000000000000000000000000000000000000000000000001557 211.0
HKD2_k127_5950123_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 543.0
HKD2_k127_5950123_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 406.0
HKD2_k127_5950123_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000002022 230.0
HKD2_k127_5950123_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000001493 117.0
HKD2_k127_5959513_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000005319 237.0
HKD2_k127_5959513_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000008694 231.0
HKD2_k127_5959513_2 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000000000000001239 208.0
HKD2_k127_5959513_3 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000001197 182.0
HKD2_k127_5959513_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000005369 129.0
HKD2_k127_5959513_5 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000004801 87.0
HKD2_k127_5959513_6 Belongs to the UPF0235 family K09131 - - 0.00000000002042 64.0
HKD2_k127_5959513_7 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000002171 64.0
HKD2_k127_5959573_0 PFAM PEBP family protein K06910,K07032 - - 0.00000000000000000000000000000000000000000004428 165.0
HKD2_k127_5959573_1 Pfam:DUF59 - - - 0.0000000000000000000000009243 106.0
HKD2_k127_5959573_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000001375 106.0
HKD2_k127_5966233_0 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000002554 172.0
HKD2_k127_5966233_1 Cytidylyltransferase-like - - - 0.0000000000000000000000000000003749 133.0
HKD2_k127_5966233_2 Cytidylyltransferase-like - - - 0.00000002828 60.0
HKD2_k127_5980194_0 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
HKD2_k127_5980194_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000002917 201.0
HKD2_k127_5980194_2 sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000002068 186.0
HKD2_k127_5980194_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000001534 104.0
HKD2_k127_5981210_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 309.0
HKD2_k127_5981210_1 protein kinase activity - - - 0.000000003767 59.0
HKD2_k127_5981567_0 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 326.0
HKD2_k127_5981567_1 peptidase - - - 0.00000000000000000000000000000009318 134.0
HKD2_k127_6002618_0 Monogalactosyldiacylglycerol synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001055 246.0
HKD2_k127_6002618_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000006256 147.0
HKD2_k127_6008047_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 578.0
HKD2_k127_6008047_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
HKD2_k127_6017092_0 Protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005365 272.0
HKD2_k127_6017092_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000002867 168.0
HKD2_k127_6017092_2 glycerophosphodiester phosphodiesterase activity - - - 0.0002009 46.0
HKD2_k127_6027495_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 274.0
HKD2_k127_6027495_1 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000891 186.0
HKD2_k127_6041348_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 563.0
HKD2_k127_6041348_1 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0000000000000004151 85.0
HKD2_k127_6042239_0 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000006306 211.0
HKD2_k127_6042239_1 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000002324 135.0
HKD2_k127_6043484_0 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000002362 129.0
HKD2_k127_6043484_1 3-carboxyethylcatechol 2,3-dioxygenase activity K04100 - 1.13.11.8 0.0000000000000000001052 88.0
HKD2_k127_6043484_2 Protein of unknown function (DUF3592) - - - 0.000000000001275 75.0
HKD2_k127_6053691_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 404.0
HKD2_k127_6066455_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.784e-221 711.0
HKD2_k127_6066455_1 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 321.0
HKD2_k127_6066455_2 PFAM RNA binding S1 domain protein - - - 0.000000000000000000009179 96.0
HKD2_k127_6066455_4 Putative zinc-binding metallo-peptidase - - - 0.00000001568 63.0
HKD2_k127_6073267_0 ATPases associated with a variety of cellular activities K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 477.0
HKD2_k127_6073267_1 double-stranded RNA RNA-DNA hybrid binding protein K03469 - 3.1.26.4 0.0000000000000000000000000000000000000002165 154.0
HKD2_k127_6078816_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 469.0
HKD2_k127_6078816_1 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000469 225.0
HKD2_k127_6078816_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
HKD2_k127_6078816_3 isoprenoid biosynthetic process K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000001063 216.0
HKD2_k127_6078816_4 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000001209 202.0
HKD2_k127_6078816_5 PFAM Family of - - - 0.000000000000000000000000000000000000000000000000000006505 194.0
HKD2_k127_6089769_0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 434.0
HKD2_k127_6089769_1 phosphatidate phosphatase activity - - - 0.0000000000000000000000000002973 121.0
HKD2_k127_6109030_0 TIGRFAM conserved - - - 0.0000000000000000000000000000000000000000000000004936 179.0
HKD2_k127_6109030_1 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000003394 149.0
HKD2_k127_6109030_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000002701 135.0
HKD2_k127_6109030_3 Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family - - - 0.000001192 57.0
HKD2_k127_611982_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 4.784e-217 687.0
HKD2_k127_611982_1 Argininosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 561.0
HKD2_k127_611982_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 496.0
HKD2_k127_611982_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 426.0
HKD2_k127_611982_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 355.0
HKD2_k127_611982_5 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007389 259.0
HKD2_k127_611982_6 - - - - 0.000000000000000000000000000000008874 138.0
HKD2_k127_611982_7 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.00000000000000000000000000002693 119.0
HKD2_k127_6120528_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000001633 128.0
HKD2_k127_6171385_0 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 400.0
HKD2_k127_6171385_1 glycerophosphodiester transmembrane transport K02026 - - 0.00000000000000000000000000000000000000000002586 163.0
HKD2_k127_6186835_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 456.0
HKD2_k127_6186835_1 Histidine kinase K00936,K01719,K01768,K02030,K02584,K10441,K13924,K20962 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.4.52,3.6.3.17,4.2.1.75,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 340.0
HKD2_k127_6186835_2 Response regulator receiver domain protein K22010 - - 0.000000000000000000000000000000000000002141 154.0
HKD2_k127_6190960_0 PFAM glycosidase PH1107-related K18785,K20885 - 2.4.1.319,2.4.1.320,2.4.1.339,2.4.1.340 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 556.0
HKD2_k127_6190960_1 transporter K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 439.0
HKD2_k127_6190960_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002132 265.0
HKD2_k127_6190960_3 amidohydrolase - - - 0.00000000000000000000000000000000004019 151.0
HKD2_k127_6190960_4 Amidohydrolase - - - 0.00000000000000000000008308 112.0
HKD2_k127_6198648_0 methyltransferase K06219 - - 0.00000000000000001499 87.0
HKD2_k127_6202843_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 336.0
HKD2_k127_6202843_1 Domain of unknown function (DUF4037) - - - 0.000000003855 59.0
HKD2_k127_6205149_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000001034 114.0
HKD2_k127_6205149_1 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000002641 123.0
HKD2_k127_6205149_2 ubiquitin binding K17987 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005773,GO:0005829,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0012505,GO:0016043,GO:0016236,GO:0022607,GO:0031410,GO:0031982,GO:0032182,GO:0034622,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0051258,GO:0051259,GO:0061919,GO:0065003,GO:0071840,GO:0097708 - 0.000000833 62.0
HKD2_k127_620650_0 ABC transporter transmembrane region K06147 - - 1.625e-223 709.0
HKD2_k127_620650_1 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000003592 205.0
HKD2_k127_620650_2 LysE type translocator - - - 0.000000000000000000000000004915 115.0
HKD2_k127_6229441_0 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 305.0
HKD2_k127_6229441_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 267.0
HKD2_k127_6254248_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 442.0
HKD2_k127_6277349_0 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 415.0
HKD2_k127_6277349_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 287.0
HKD2_k127_6277349_2 Glucose sorbosone - - - 0.00000000000000000000000000000000000000000000000005997 181.0
HKD2_k127_6277349_3 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000008266 86.0
HKD2_k127_628074_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002526 259.0
HKD2_k127_628074_1 Psort location Cytoplasmic, score K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
HKD2_k127_628074_2 PFAM Diguanylate phosphodiesterase, EAL domain - - - 0.000000000000003932 88.0
HKD2_k127_628074_3 - - - - 0.000000000002002 80.0
HKD2_k127_628074_4 Domain of unknown function (DUF5060) - - - 0.0000000003781 69.0
HKD2_k127_628663_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000002781 137.0
HKD2_k127_6288312_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 1.582e-242 759.0
HKD2_k127_6288312_1 Belongs to the DEAD box helicase family K03732,K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002847 284.0
HKD2_k127_6288312_2 FAD binding domain K00104,K00803 - 1.1.3.15,2.5.1.26 0.000003172 49.0
HKD2_k127_6291384_0 Pkd domain containing protein K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000002535 271.0
HKD2_k127_6291384_1 PFAM binding-protein-dependent transport systems inner membrane component K10233 - - 0.0000001643 64.0
HKD2_k127_6310493_0 Transcriptional regulator K02529,K07506 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 415.0
HKD2_k127_6310493_1 Transcriptional regulator K02529,K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 396.0
HKD2_k127_6310493_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000002908 149.0
HKD2_k127_6310493_3 diguanylate cyclase K07315,K11444 - 2.7.7.65,3.1.3.3 0.00000000000000000000000000000002217 146.0
HKD2_k127_6310493_4 Domain of unknown function (DUF4129) - - - 0.0000000000000000000002104 111.0
HKD2_k127_6310740_0 phosphoenolpyruvate synthase K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 389.0
HKD2_k127_6332112_0 elongation factor Tu domain 2 protein K06207 - - 1.71e-280 873.0
HKD2_k127_6343794_0 Acetyl xylan esterase (AXE1) K01060 - 3.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 441.0
HKD2_k127_6343794_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 435.0
HKD2_k127_6343794_2 Cupin domain - - - 0.000000000000000000000000001001 117.0
HKD2_k127_6388801_0 alginic acid biosynthetic process K09815,K15727,K20276 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000001549 133.0
HKD2_k127_6388801_1 Calx-beta domain - - - 0.000000000000000000000000005799 116.0
HKD2_k127_6408875_0 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009637 266.0
HKD2_k127_6408875_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000001065 155.0
HKD2_k127_6408875_2 Peptidase MA superfamily - - - 0.0000000000000000000000000000000108 142.0
HKD2_k127_6408875_3 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000003638 92.0
HKD2_k127_6408875_4 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000007332 81.0
HKD2_k127_6417269_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 422.0
HKD2_k127_6417269_1 PFAM glycoside hydrolase 15-related K01178 - 3.2.1.3 0.0000000000000000000000000000000000000000000002402 170.0
HKD2_k127_6422545_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 511.0
HKD2_k127_6422545_1 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000001642 195.0
HKD2_k127_6434886_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000001202 117.0
HKD2_k127_6434886_1 Rhodanese Homology Domain - - - 0.0000000000000000000000006904 113.0
HKD2_k127_6469708_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000004135 247.0
HKD2_k127_6479555_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000007465 229.0
HKD2_k127_6479555_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000002636 163.0
HKD2_k127_6479555_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000001481 148.0
HKD2_k127_6479555_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000007208 85.0
HKD2_k127_6486184_0 lipolytic protein G-D-S-L family - - - 0.00000001223 65.0
HKD2_k127_6507067_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.3e-255 811.0
HKD2_k127_6507067_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000002084 164.0
HKD2_k127_6513816_0 serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000002582 135.0
HKD2_k127_6513816_1 Forkhead-associated protein - - - 0.000000007326 69.0
HKD2_k127_6520054_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004438 259.0
HKD2_k127_6520054_1 - - - - 0.00000000000000000000000007932 111.0
HKD2_k127_652092_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001582 279.0
HKD2_k127_652092_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000002586 188.0
HKD2_k127_6529902_0 PAS domain containing protein - - - 0.00000000000000000000000000000000000003538 161.0
HKD2_k127_6529902_1 NnrU protein K21310 - 2.1.1.334 0.00000000000000000000000000003529 127.0
HKD2_k127_6533240_0 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 465.0
HKD2_k127_6533240_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000002887 243.0
HKD2_k127_6548402_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 497.0
HKD2_k127_6548933_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 328.0
HKD2_k127_6548933_1 PFAM glycoside hydrolase family 29 (alpha-L-fucosidase) K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001908 282.0
HKD2_k127_6548933_2 PFAM Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000001059 147.0
HKD2_k127_6574932_0 Two component transcriptional regulator, winged helix family K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009678 262.0
HKD2_k127_6574932_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000004157 184.0
HKD2_k127_6582278_0 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000002674 174.0
HKD2_k127_6587945_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein - - - 5.346e-222 702.0
HKD2_k127_6587945_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K14090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 554.0
HKD2_k127_6587945_10 4Fe-4S binding domain K14091 - - 0.000000000000000000000000000000000000000000005107 180.0
HKD2_k127_6587945_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332,K13378 - 1.6.5.3 0.0000000000000000000000000000000001308 148.0
HKD2_k127_6587945_12 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000002385 128.0
HKD2_k127_6587945_14 hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000002849 97.0
HKD2_k127_6587945_15 Multisubunit Na H antiporter MnhC subunit K00340,K05567 - 1.6.5.3 0.00000000000000000459 91.0
HKD2_k127_6587945_2 ATP synthesis coupled electron transport K00342,K00343,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 481.0
HKD2_k127_6587945_3 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 442.0
HKD2_k127_6587945_4 quinone binding K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 400.0
HKD2_k127_6587945_5 Transcriptional regulator K02529,K07506 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 354.0
HKD2_k127_6587945_6 Periplasmic binding protein LacI transcriptional regulator K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 292.0
HKD2_k127_6587945_7 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002132 265.0
HKD2_k127_6587945_8 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008988 248.0
HKD2_k127_6587945_9 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000004707 184.0
HKD2_k127_6591501_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 2.778e-320 989.0
HKD2_k127_6591501_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 382.0
HKD2_k127_6591501_2 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000004911 216.0
HKD2_k127_6591501_3 Bacterial protein of unknown function (DUF937) - - - 0.0000000000000000000000000000000000005201 147.0
HKD2_k127_6591501_4 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000171 48.0
HKD2_k127_6603909_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 349.0
HKD2_k127_661000_0 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000005915 234.0
HKD2_k127_661000_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000001168 93.0
HKD2_k127_6613324_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 633.0
HKD2_k127_6613324_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 306.0
HKD2_k127_6614297_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
HKD2_k127_6614297_1 histidine kinase A domain protein K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001088 225.0
HKD2_k127_6614297_2 - - - - 0.000000000000000000000000000000000000000000002281 174.0
HKD2_k127_6614297_3 Rhodanese domain protein - - - 0.0000000000000000000000000001504 118.0
HKD2_k127_6615655_0 phosphorelay signal transduction system - GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000001372 178.0
HKD2_k127_663216_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 322.0
HKD2_k127_663216_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001469 291.0
HKD2_k127_6633737_0 Bacterial extracellular solute-binding protein K10117 - - 6.769e-204 643.0
HKD2_k127_6633737_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 542.0
HKD2_k127_6633737_2 Binding-protein-dependent transport system inner membrane component K10118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 403.0
HKD2_k127_6633737_3 PFAM Binding-protein-dependent transport system inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000806 216.0
HKD2_k127_6642893_0 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 592.0
HKD2_k127_6642893_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 511.0
HKD2_k127_6642893_2 Putative stress-induced transcription regulator - - - 0.000000000000000000000000000000000000000000001188 172.0
HKD2_k127_6642893_4 - - - - 0.0009538 45.0
HKD2_k127_6669339_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001092 279.0
HKD2_k127_6669339_1 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000008262 57.0
HKD2_k127_6669339_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0005555 44.0
HKD2_k127_667264_0 amidohydrolase - - - 0.00000000002352 76.0
HKD2_k127_6674709_0 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 311.0
HKD2_k127_6674709_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000001503 214.0
HKD2_k127_6674709_2 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.0000000000000000000000000000000003443 143.0
HKD2_k127_6674987_0 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 305.0
HKD2_k127_6674987_1 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000003243 209.0
HKD2_k127_6674987_2 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000001453 194.0
HKD2_k127_6674987_3 Aldo/keto reductase family K07079 - - 0.000000000000003698 77.0
HKD2_k127_6681805_0 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 587.0
HKD2_k127_6694060_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 6.394e-263 830.0
HKD2_k127_6694060_1 PFAM LmbE family protein K18455 - 3.5.1.115 0.0000000000000000000000000000000000000000000000000000000000000005215 226.0
HKD2_k127_6694060_2 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000004499 104.0
HKD2_k127_6694581_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 354.0
HKD2_k127_6702493_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 3.132e-268 831.0
HKD2_k127_6702493_1 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 0.0000000000000000000000000000000000000000000000000000007138 218.0
HKD2_k127_6702493_2 glycosyl transferase family 2 - - - 0.0000000000347 73.0
HKD2_k127_6703241_0 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.0000000000000000000000000000000000000000000000000000000000000000003822 243.0
HKD2_k127_6703241_1 ATPases associated with a variety of cellular activities K03701 - - 0.0000000000000000000000000000000000000000001329 162.0
HKD2_k127_6703967_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 457.0
HKD2_k127_6719130_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 296.0
HKD2_k127_6724128_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 467.0
HKD2_k127_6724128_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K18827 - 2.1.1.222,2.1.1.294,2.1.1.64,2.7.1.181 0.000000000000000000000000000000000000000006266 156.0
HKD2_k127_6724128_3 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000000002813 127.0
HKD2_k127_6727080_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1135.0
HKD2_k127_6727080_1 lipid binding - - - 0.00000000000000000000000000000000000000000002291 166.0
HKD2_k127_6755725_0 FAD linked oxidase domain protein K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 477.0
HKD2_k127_6765743_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 391.0
HKD2_k127_6765743_1 Acyltransferase family - - - 0.0000001646 54.0
HKD2_k127_678652_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 319.0
HKD2_k127_678652_1 xylan catabolic process K03932 - - 0.00000000000000000000000001026 118.0
HKD2_k127_6790705_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K01710,K02377 - 1.1.1.271,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 311.0
HKD2_k127_6790705_1 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000008081 141.0
HKD2_k127_6792559_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 375.0
HKD2_k127_6792559_1 guanyl-nucleotide exchange factor activity K20276 - - 0.0000000000000000000000000000000005449 147.0
HKD2_k127_6792559_2 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000122 126.0
HKD2_k127_6792559_3 Ig-like domain from next to BRCA1 gene - - - 0.00000000000000000000000006741 124.0
HKD2_k127_6792559_4 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000001221 120.0
HKD2_k127_680512_0 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000005954 159.0
HKD2_k127_680512_1 Large extracellular alpha-helical protein K06894 - - 0.000000000000001323 80.0
HKD2_k127_6815787_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 3.654e-284 881.0
HKD2_k127_683697_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 341.0
HKD2_k127_6849210_0 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 592.0
HKD2_k127_6849210_1 glucuronate isomerase K01812 - 5.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 485.0
HKD2_k127_6849210_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 479.0
HKD2_k127_6849210_3 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 437.0
HKD2_k127_6849210_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 314.0
HKD2_k127_6849210_5 Gluconokinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000006868 173.0
HKD2_k127_6853774_0 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 370.0
HKD2_k127_6853774_1 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000005105 259.0
HKD2_k127_6853774_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000003084 68.0
HKD2_k127_6860182_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 574.0
HKD2_k127_6860780_0 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000354 257.0
HKD2_k127_6860780_1 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000008022 228.0
HKD2_k127_6862439_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 497.0
HKD2_k127_6862439_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000001671 257.0
HKD2_k127_6862439_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000002079 156.0
HKD2_k127_6862439_3 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000000000208 154.0
HKD2_k127_6862439_4 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000002422 141.0
HKD2_k127_6862439_5 Protein of unknown function (DUF3592) - - - 0.0000007079 57.0
HKD2_k127_6863148_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002719 253.0
HKD2_k127_6863148_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000005762 246.0
HKD2_k127_6863148_2 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000002134 219.0
HKD2_k127_6863148_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.00000000000000000000000000000199 126.0
HKD2_k127_6868050_0 SMART alpha amylase catalytic sub domain K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 411.0
HKD2_k127_6868367_0 N-terminal 7TM region of histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001012 274.0
HKD2_k127_6875711_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 368.0
HKD2_k127_6875711_1 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 308.0
HKD2_k127_6904414_1 serine threonine protein kinase - - - 0.0000008195 57.0
HKD2_k127_6915837_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 314.0
HKD2_k127_6915837_1 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.000000000000000000000000000000000000002867 157.0
HKD2_k127_6915837_2 iron-sulfur cluster assembly - - - 0.000000000000000000000243 108.0
HKD2_k127_6920885_0 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 321.0
HKD2_k127_6920885_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 304.0
HKD2_k127_6920885_2 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000002127 253.0
HKD2_k127_6920885_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000008491 221.0
HKD2_k127_6928287_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000005207 144.0
HKD2_k127_6928287_1 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000004897 79.0
HKD2_k127_6928287_2 Bacteriophage peptidoglycan hydrolase - - - 0.00000000007843 74.0
HKD2_k127_6930895_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000001941 233.0
HKD2_k127_6931994_0 methyltransferase activity - - - 0.00000000000000001591 93.0
HKD2_k127_6933545_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 6.822e-208 662.0
HKD2_k127_6933545_1 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 474.0
HKD2_k127_6953162_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000009869 149.0
HKD2_k127_6953162_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.0000000000000000000000000000000004443 136.0
HKD2_k127_6961497_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000005067 249.0
HKD2_k127_6961497_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000001593 211.0
HKD2_k127_6961497_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000002395 188.0
HKD2_k127_6967999_0 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000195 278.0
HKD2_k127_6967999_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007571 274.0
HKD2_k127_6967999_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000002569 237.0
HKD2_k127_6967999_3 Amino acid permease - - - 0.000000008685 68.0
HKD2_k127_6968140_0 Oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 544.0
HKD2_k127_6968140_1 pyridine nucleotide-disulfide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 451.0
HKD2_k127_6968140_2 Glycosyl hydrolases family 16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 286.0
HKD2_k127_6968140_3 Protein of unknown function (DUF1667) - - - 0.0000000001058 63.0
HKD2_k127_6984430_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 358.0
HKD2_k127_6993613_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000038 218.0
HKD2_k127_7002657_0 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 298.0
HKD2_k127_7012291_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 551.0
HKD2_k127_7017188_0 nitrite transmembrane transporter activity K02532 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 426.0
HKD2_k127_7017188_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 406.0
HKD2_k127_7017188_2 PFAM ComEC Rec2-related protein K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002613 304.0
HKD2_k127_7019054_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 2.899e-270 843.0
HKD2_k127_7028676_0 Domain of unknown function (DUF4352) - - - 0.0000000001449 72.0
HKD2_k127_7028676_1 Ribosomal protein L34 K02914 - - 0.0000002493 52.0
HKD2_k127_7047737_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 465.0
HKD2_k127_7047737_1 Pas domain K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000003691 228.0
HKD2_k127_7047737_2 cheY-homologous receiver domain K11443 - - 0.000000000000000000000000000000000000000000003674 179.0
HKD2_k127_7059181_0 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000006326 138.0
HKD2_k127_7059181_1 Histidine kinase - - - 0.000000000000000000000000000000149 138.0
HKD2_k127_7061299_0 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03753,K13818 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000006696 218.0
HKD2_k127_7061299_1 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000000000000000000175 153.0
HKD2_k127_7061299_2 membrane transporter protein K07090 - - 0.000000000000000000000001072 108.0
HKD2_k127_7061299_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000001061 90.0
HKD2_k127_7061299_4 - - - - 0.0000005415 51.0
HKD2_k127_7078645_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000339 220.0
HKD2_k127_7078645_1 PFAM peptidase - - - 0.000000000000000000000000000000000001301 148.0
HKD2_k127_7078645_2 GIY-YIG catalytic domain protein K07461 - - 0.00000000000000003327 93.0
HKD2_k127_7078645_3 RRNA methyltransferase AviRa K21515 - 2.1.1.209 0.0000003779 53.0
HKD2_k127_7078645_4 Squalene--hopene cyclase - - - 0.000002001 56.0
HKD2_k127_7088932_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 359.0
HKD2_k127_7088932_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 284.0
HKD2_k127_7088932_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0003674,GO:0003824,GO:0004068,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006508,GO:0006520,GO:0006522,GO:0006523,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009108,GO:0009110,GO:0009987,GO:0010467,GO:0015939,GO:0015940,GO:0016053,GO:0016485,GO:0016540,GO:0016829,GO:0016830,GO:0016831,GO:0019538,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.11 0.000000000000000000000000000000000000699 142.0
HKD2_k127_7098847_0 TIGRFAM metal dependent phophohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 303.0
HKD2_k127_7098847_1 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000691 240.0
HKD2_k127_7098847_2 - - - - 0.00000000000000000000000000000000001055 140.0
HKD2_k127_7098847_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000004264 67.0
HKD2_k127_7106872_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 417.0
HKD2_k127_7106872_1 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000593 230.0
HKD2_k127_7106872_2 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000004184 210.0
HKD2_k127_7106872_3 PFAM secretion protein HlyD family protein K01993 - - 0.0000000000000000000000000000000000000000003774 182.0
HKD2_k127_7106872_4 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000002066 135.0
HKD2_k127_7106872_5 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000007661 102.0
HKD2_k127_7120475_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 321.0
HKD2_k127_7124254_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000009629 231.0
HKD2_k127_7124254_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000001146 158.0
HKD2_k127_7124254_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000003556 114.0
HKD2_k127_7127087_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 352.0
HKD2_k127_7127087_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000001007 209.0
HKD2_k127_7127087_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000009719 194.0
HKD2_k127_7127087_3 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000001189 154.0
HKD2_k127_7127087_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000005617 141.0
HKD2_k127_7127087_5 PFAM OsmC family protein K07397 - - 0.00000000000000000000000000005016 124.0
HKD2_k127_7127087_6 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000003361 114.0
HKD2_k127_7127087_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000005278 66.0
HKD2_k127_7137801_0 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 555.0
HKD2_k127_7137801_1 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 349.0
HKD2_k127_7137801_2 PFAM CBS domain - - - 0.000000000002221 76.0
HKD2_k127_7146799_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 300.0
HKD2_k127_7146799_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000005012 75.0
HKD2_k127_7150689_0 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000004336 237.0
HKD2_k127_7150689_1 PFAM transglutaminase domain protein - - - 0.00004773 53.0
HKD2_k127_7158597_0 glycoside hydrolase family 2 sugar binding K01192 - 3.2.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 426.0
HKD2_k127_7158597_1 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000000000000000000002094 207.0
HKD2_k127_7158597_2 peptidase inhibitor activity - - - 0.00000000000000000417 96.0
HKD2_k127_7158597_3 Cysteine-rich secretory protein family - - - 0.00000000001274 77.0
HKD2_k127_7186891_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 4.345e-212 671.0
HKD2_k127_7186891_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 375.0
HKD2_k127_7186891_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001533 267.0
HKD2_k127_7186891_3 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000001091 147.0
HKD2_k127_7186891_4 cellulose binding - - - 0.000000001591 68.0
HKD2_k127_7189496_0 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006526 272.0
HKD2_k127_7189496_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000004071 173.0
HKD2_k127_7193724_0 Pectinacetylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001362 250.0
HKD2_k127_7198889_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 5.852e-230 717.0
HKD2_k127_7198889_1 NADH dehydrogenase K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003299 180.0
HKD2_k127_7213845_0 KR domain - - - 0.000000000000000000000000000000000001564 150.0
HKD2_k127_7223059_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1037.0
HKD2_k127_7223059_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006435 201.0
HKD2_k127_7223059_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001224 77.0
HKD2_k127_7232284_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 348.0
HKD2_k127_7232284_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000000003088 127.0
HKD2_k127_7232284_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000003287 64.0
HKD2_k127_7232284_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000221 49.0
HKD2_k127_7233280_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 356.0
HKD2_k127_7233280_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 329.0
HKD2_k127_7233280_2 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.00000000000000000000000000000000000000002349 159.0
HKD2_k127_728248_0 histidine kinase A domain protein - - - 1.495e-263 867.0
HKD2_k127_728248_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 383.0
HKD2_k127_728248_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003271 246.0
HKD2_k127_728248_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000001134 182.0
HKD2_k127_728319_0 Belongs to the glycosyl hydrolase 30 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 538.0
HKD2_k127_728319_1 AraC-like ligand binding domain - - - 0.00000009054 53.0
HKD2_k127_7304433_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 601.0
HKD2_k127_7327425_0 alcohol dehydrogenase K00008,K05351 - 1.1.1.14,1.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 500.0
HKD2_k127_7327425_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000134 86.0
HKD2_k127_7336777_0 PHP domain protein K02347 - - 6.642e-197 632.0
HKD2_k127_7336777_1 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 388.0
HKD2_k127_7362093_1 B3 4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003491 261.0
HKD2_k127_7369501_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004253 226.0
HKD2_k127_7369501_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000008542 174.0
HKD2_k127_7369501_2 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000008672 169.0
HKD2_k127_7369501_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000004403 159.0
HKD2_k127_7369501_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000002837 152.0
HKD2_k127_7369501_5 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000005866 69.0
HKD2_k127_7412_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001248 278.0
HKD2_k127_743397_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 2.817e-209 657.0
HKD2_k127_743397_1 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 423.0
HKD2_k127_743397_2 Peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 375.0
HKD2_k127_743397_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000001303 220.0
HKD2_k127_7443258_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 8.546e-315 979.0
HKD2_k127_7444597_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005237 259.0
HKD2_k127_7444597_1 Glycoside-hydrolase family GH114 - - - 0.000000000000000000000000000000000000000000000000000000000000000001781 229.0
HKD2_k127_7456025_0 - K08223 - - 0.00000000000000000000000000000000000000000003162 175.0
HKD2_k127_7456025_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000401 151.0
HKD2_k127_7456025_2 Acetyltransferase (GNAT) domain - - - 0.00000001974 58.0
HKD2_k127_7474191_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000001839 163.0
HKD2_k127_7474191_1 Belongs to the glycosyl hydrolase 43 family - - - 0.000000000000000000000000000000002643 148.0
HKD2_k127_7477112_0 Protein of unknown function (DUF1214) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
HKD2_k127_7477112_1 Protein of unknown function (DUF1254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000802 269.0
HKD2_k127_7477112_2 AAA domain - - - 0.000000000000000000000000000000000000000000000009475 176.0
HKD2_k127_7477112_3 translation initiation factor activity K06996 - - 0.000000000001874 74.0
HKD2_k127_748685_0 ABC-2 family transporter protein K01992 - - 0.000001658 61.0
HKD2_k127_7492024_0 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000000002607 131.0
HKD2_k127_7492024_1 Beta-lactamase superfamily domain - - - 0.000000000000000003969 93.0
HKD2_k127_7494489_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000001666 111.0
HKD2_k127_7494489_1 Domain of unknown function (DUF4380) - - - 0.00000000000000000000002184 102.0
HKD2_k127_7498020_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 389.0
HKD2_k127_7498020_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.000000000000000000000000000000000000000000001633 166.0
HKD2_k127_7502289_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003302 270.0
HKD2_k127_7502289_1 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000353 252.0
HKD2_k127_7502289_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000005992 98.0
HKD2_k127_7502289_3 Glycosyl transferase 4-like domain - - - 0.0000000000000001616 86.0
HKD2_k127_7515868_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 414.0
HKD2_k127_7515868_1 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000001367 200.0
HKD2_k127_7520555_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000001334 193.0
HKD2_k127_7520555_1 Periplasmic component of the Tol biopolymer transport system - - - 0.00001057 58.0
HKD2_k127_7525471_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 340.0
HKD2_k127_7525471_1 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000001566 201.0
HKD2_k127_7525471_2 Divergent PAP2 family K09775 - - 0.0000000000000000000000000000000000000000000000001023 183.0
HKD2_k127_7525471_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000005263 95.0
HKD2_k127_7525471_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000006736 65.0
HKD2_k127_7537721_0 WD40-like Beta Propeller Repeat - - - 0.0000000001273 71.0
HKD2_k127_7541662_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003076 286.0
HKD2_k127_7541662_1 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001683 263.0
HKD2_k127_7541662_2 Involved in the tonB-independent uptake of proteins K01771 - 4.6.1.13 0.00000000000000000000000000000003962 141.0
HKD2_k127_7541662_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000003236 113.0
HKD2_k127_7541662_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000001071 93.0
HKD2_k127_7541662_5 peptidase - - - 0.00000009817 57.0
HKD2_k127_7569605_0 Two component transcriptional regulator, winged helix family K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 291.0
HKD2_k127_7569605_1 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.00000000000000000000004058 111.0
HKD2_k127_7569605_2 - - - - 0.00000000000004932 79.0
HKD2_k127_7569605_3 cellulose binding K15924 - 3.2.1.136 0.000000001622 61.0
HKD2_k127_7611583_0 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 493.0
HKD2_k127_7611583_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004495 263.0
HKD2_k127_7611583_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000001815 163.0
HKD2_k127_7613470_0 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000001404 213.0
HKD2_k127_7618935_0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.00000000000000000000000000001211 137.0
HKD2_k127_7632163_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.021e-197 635.0
HKD2_k127_7640650_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
HKD2_k127_7640650_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000009671 168.0
HKD2_k127_7640984_0 - - - - 0.000000000000000000000000000000001807 134.0
HKD2_k127_7640984_1 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000006352 106.0
HKD2_k127_7640984_2 - - - - 0.000000000000000002641 94.0
HKD2_k127_7659911_0 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 520.0
HKD2_k127_7659911_1 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 362.0
HKD2_k127_7659911_2 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.000000000003697 68.0
HKD2_k127_7666725_0 TPR repeat - - - 0.0000003072 64.0
HKD2_k127_7674789_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 386.0
HKD2_k127_7674789_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000003455 110.0
HKD2_k127_7686510_0 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006121 250.0
HKD2_k127_7687411_0 Glycosyl hydrolases family 39 - - - 0.000000000004178 79.0
HKD2_k127_7687411_1 Calx-beta domain - - - 0.00000000187 71.0
HKD2_k127_7690520_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 312.0
HKD2_k127_7690520_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000003926 223.0
HKD2_k127_7690520_2 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000002497 211.0
HKD2_k127_7690520_3 methyltransferase - - - 0.0000000000000000000000000000000000000004819 156.0
HKD2_k127_7690520_4 Glycosyl transferases group 1 - - - 0.000000004161 68.0
HKD2_k127_7695661_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 333.0
HKD2_k127_7695661_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000006122 229.0
HKD2_k127_7696189_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000002604 230.0
HKD2_k127_7696189_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000017 191.0
HKD2_k127_7696189_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000005634 186.0
HKD2_k127_7703351_0 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 323.0
HKD2_k127_7703351_1 KDPG and KHG aldolase K01625 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000001027 240.0
HKD2_k127_7703351_2 Short-chain dehydrogenase reductase sdr K00065 - 1.1.1.127 0.000000000000000000000000002716 113.0
HKD2_k127_7722720_0 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 286.0
HKD2_k127_7722720_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000002885 219.0
HKD2_k127_7722720_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002324 217.0
HKD2_k127_7729617_0 Cellulase N-terminal ig-like domain - - - 3.599e-249 797.0
HKD2_k127_7730072_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 419.0
HKD2_k127_7730072_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000335 226.0
HKD2_k127_7732448_0 Asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
HKD2_k127_7732448_2 - - - - 0.000000000000002056 86.0
HKD2_k127_7739191_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 347.0
HKD2_k127_7739191_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000003316 169.0
HKD2_k127_7739191_2 Membrane - - - 0.000000000000000000000000000000000007486 154.0
HKD2_k127_7747301_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000006391 152.0
HKD2_k127_7747301_1 FtsX-like permease family K02004 - - 0.00000000000000000951 96.0
HKD2_k127_7749523_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.052e-281 876.0
HKD2_k127_7749523_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000002955 112.0
HKD2_k127_7752761_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 324.0
HKD2_k127_7752761_1 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002335 269.0
HKD2_k127_7752761_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000007325 201.0
HKD2_k127_7752761_3 - - - - 0.0000000000000000000000001053 118.0
HKD2_k127_7752761_4 Winged helix DNA-binding domain - - - 0.0000000000000000000001023 109.0
HKD2_k127_7752761_5 GrpB protein - - - 0.000000000000000000000721 102.0
HKD2_k127_7752761_6 - - - - 0.0000000000000004673 89.0
HKD2_k127_7752761_7 Proteolipid membrane potential modulator - - - 0.000000000000001587 78.0
HKD2_k127_7752761_8 Belongs to the peptidase M50B family - - - 0.00005434 54.0
HKD2_k127_7752761_9 - - - - 0.0004289 50.0
HKD2_k127_7776636_0 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 308.0
HKD2_k127_7776636_1 methyltransferase - - - 0.000000000000000000003164 98.0
HKD2_k127_7781597_0 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 453.0
HKD2_k127_7781597_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000404 247.0
HKD2_k127_7781597_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000003545 201.0
HKD2_k127_7805207_0 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000002194 188.0
HKD2_k127_7823146_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 480.0
HKD2_k127_7823146_1 DinB family - - - 0.00000000000000000000000002222 119.0
HKD2_k127_7828617_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.337e-214 670.0
HKD2_k127_7831702_0 (ABC) transporter K06147,K11085 - - 5.282e-229 722.0
HKD2_k127_7843592_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000006733 167.0
HKD2_k127_7843592_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000007118 146.0
HKD2_k127_7843592_2 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001195 132.0
HKD2_k127_7843592_3 Belongs to the UPF0109 family K06960 - - 0.0000000000000000004149 89.0
HKD2_k127_7847059_0 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003093 267.0
HKD2_k127_7847059_1 methyltransferase activity - - - 0.00000000000000000008022 93.0
HKD2_k127_7859065_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004682 249.0
HKD2_k127_7859065_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000005179 230.0
HKD2_k127_7859065_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000007378 178.0
HKD2_k127_7859065_3 Cell wall-active antibiotics response 4TMS YvqF - - - 0.0000000000000000000000000000000000000000000017 172.0
HKD2_k127_7859065_4 - - - - 0.000000000005943 71.0
HKD2_k127_7859672_0 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 520.0
HKD2_k127_7859672_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000004134 196.0
HKD2_k127_7859672_3 Protein of unknown function (DUF1461) - - - 0.000000000000000000000000000000001578 145.0
HKD2_k127_7880548_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 481.0
HKD2_k127_7889486_0 glutaminyl-tRNA K01886 - 6.1.1.18 9.132e-226 711.0
HKD2_k127_7889486_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 387.0
HKD2_k127_7889486_2 Transcriptional regulatory protein, C terminal K07669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001703 280.0
HKD2_k127_7889486_3 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000005 220.0
HKD2_k127_7889486_4 Protein of unknown function (DUF1232) - - - 0.000000000002895 71.0
HKD2_k127_7892762_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000001817 158.0
HKD2_k127_7892762_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000005556 109.0
HKD2_k127_7892836_0 Apoptosis-inducing factor, mitochondrion-associated, C-term - - - 1.09e-219 685.0
HKD2_k127_7892836_1 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000000000000000000000000003834 194.0
HKD2_k127_7892836_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000008874 66.0
HKD2_k127_7892836_3 RibD C-terminal domain - - - 0.00000002971 55.0
HKD2_k127_7892840_0 DNA ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 404.0
HKD2_k127_7892840_1 - - - - 0.00000000000000000001098 93.0
HKD2_k127_7903246_0 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000005231 205.0
HKD2_k127_7903246_1 4-vinyl reductase, 4VR K07013,K17763 - - 0.0000003636 59.0
HKD2_k127_7912345_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000108 273.0
HKD2_k127_7912345_1 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000001453 172.0
HKD2_k127_7912345_2 metal-dependent phosphohydrolase, HD sub domain K07037 - - 0.000000000000000000000000000000000000000000006246 176.0
HKD2_k127_7920669_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 486.0
HKD2_k127_7920669_1 PFAM extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 428.0
HKD2_k127_7920669_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001524 283.0
HKD2_k127_7920669_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000841 177.0
HKD2_k127_7920669_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000001169 131.0
HKD2_k127_7923116_0 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000202 188.0
HKD2_k127_7923116_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000008399 164.0
HKD2_k127_7923288_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 5.061e-240 751.0
HKD2_k127_7935581_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 413.0
HKD2_k127_7955782_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 5.843e-211 668.0
HKD2_k127_7955782_1 copper-translocating P-type ATPase K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 366.0
HKD2_k127_7955782_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000004806 127.0
HKD2_k127_7955784_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 411.0
HKD2_k127_7955784_1 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002215 279.0
HKD2_k127_7955784_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000006783 239.0
HKD2_k127_7959163_1 - - - - 0.0007648 49.0
HKD2_k127_7963541_0 carbohydrate binding K13688 - - 0.0 1340.0
HKD2_k127_7969826_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 280.0
HKD2_k127_7972986_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 300.0
HKD2_k127_7972986_1 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000009854 66.0
HKD2_k127_7981108_0 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 621.0
HKD2_k127_7981108_1 - - - - 0.00000000000000000003351 94.0
HKD2_k127_7994523_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000001474 212.0
HKD2_k127_7994523_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000006676 167.0
HKD2_k127_800312_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 556.0
HKD2_k127_800312_1 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000001961 103.0
HKD2_k127_801707_0 hydrolase, family 3 K05349 - 3.2.1.21 2.39e-265 838.0
HKD2_k127_801707_1 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 402.0
HKD2_k127_801707_2 amine oxidase - - - 0.000000000000000000001109 98.0
HKD2_k127_801707_3 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000005283 98.0
HKD2_k127_8019321_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 264.0
HKD2_k127_8019321_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000002724 227.0
HKD2_k127_8035198_0 ABC-type multidrug transport system ATPase K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 421.0
HKD2_k127_8035198_1 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000001117 203.0
HKD2_k127_8035198_2 - K01992 - - 0.00000000000000000000000000000000000000000000000001815 189.0
HKD2_k127_8042240_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 2.818e-215 676.0
HKD2_k127_8061574_0 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000001988 217.0
HKD2_k127_8061574_1 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000005247 180.0
HKD2_k127_8061574_2 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000001743 168.0
HKD2_k127_8061574_3 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000005569 136.0
HKD2_k127_8065755_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 1.229e-271 865.0
HKD2_k127_8065755_1 Putative NAD(P)-binding K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003123 256.0
HKD2_k127_8065755_2 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000001679 210.0
HKD2_k127_8065755_3 Amino acid permease - - - 0.0000000001316 74.0
HKD2_k127_8066794_0 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 319.0
HKD2_k127_8066794_1 Bacitracin ABC transporter permease K01992 - - 0.00000000000000000000000000000000000000000000000000000001196 208.0
HKD2_k127_8066794_2 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000003377 107.0
HKD2_k127_8066794_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000001416 91.0
HKD2_k127_8066794_4 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000002191 70.0
HKD2_k127_806822_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001499 266.0
HKD2_k127_806822_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000001013 199.0
HKD2_k127_806822_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000007433 106.0
HKD2_k127_806822_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000001545 105.0
HKD2_k127_806822_4 plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K01802,K07533 - 5.2.1.8 0.000000002153 70.0
HKD2_k127_8069089_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.284e-278 871.0
HKD2_k127_8069089_1 WD40 repeats - - - 0.000000000000000000002795 100.0
HKD2_k127_8072588_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 432.0
HKD2_k127_8072926_0 Belongs to the transketolase family K00615 - 2.2.1.1 1.217e-252 792.0
HKD2_k127_8073778_0 Lipid A biosynthesis K02517 - 2.3.1.241 0.000001476 60.0
HKD2_k127_8075340_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 362.0
HKD2_k127_8075340_1 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 336.0
HKD2_k127_8075340_2 COGs COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000001673 231.0
HKD2_k127_8075340_3 PFAM Translin K07477 - - 0.0000000000001986 71.0
HKD2_k127_8075951_0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000008683 232.0
HKD2_k127_8075951_1 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000212 119.0
HKD2_k127_8075951_2 Bacterial SH3 domain - - - 0.0000000002409 70.0
HKD2_k127_8075951_3 PHP domain protein - - - 0.00001262 49.0
HKD2_k127_8076082_0 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000001198 165.0
HKD2_k127_8076082_1 PFAM Diacylglycerol kinase, catalytic domain - - - 0.000000000000000000000000000000000001025 144.0
HKD2_k127_8077518_0 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000001013 199.0
HKD2_k127_8077518_1 Polymer-forming cytoskeletal - - - 0.000000000000000000000000002219 127.0
HKD2_k127_8135991_0 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 293.0
HKD2_k127_8135991_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000006217 173.0
HKD2_k127_8135991_2 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000006973 72.0
HKD2_k127_8137119_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K00972 - 2.7.7.23,2.7.7.83 0.000000000000000000000000000000000000000000002743 167.0
HKD2_k127_8137119_1 electron transfer activity K05337 - - 0.0000000000000000000000000000001177 124.0
HKD2_k127_8137119_2 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.00000000000000000000000603 106.0
HKD2_k127_8141169_0 Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides K03478 - 3.5.1.105 0.000000000000000000000000000000000000001558 157.0
HKD2_k127_8141169_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000001555 100.0
HKD2_k127_8149492_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 518.0
HKD2_k127_8149492_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 502.0
HKD2_k127_8149492_2 Domain of unknown function (DUF4156) - - - 0.0001351 46.0
HKD2_k127_8149492_3 Protein of unknown function (DUF3313) - - - 0.0001423 54.0
HKD2_k127_8153322_0 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000002295 153.0
HKD2_k127_8153322_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000001766 56.0
HKD2_k127_8153322_3 Putative adhesin - - - 0.00001609 57.0
HKD2_k127_8153322_4 Bacterial regulatory protein, Fis family K02481 - - 0.0001517 53.0
HKD2_k127_8158837_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002614 271.0
HKD2_k127_8158837_1 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000113 147.0
HKD2_k127_8159059_0 Alcohol dehydrogenase GroES-like domain K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 451.0
HKD2_k127_8159059_1 cellulose binding - - - 0.000000003531 68.0
HKD2_k127_8159059_2 Rhodanese Homology Domain - - - 0.000005458 52.0
HKD2_k127_8159418_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 312.0
HKD2_k127_8159418_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000003465 238.0
HKD2_k127_816453_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 518.0
HKD2_k127_8172878_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.217e-308 955.0
HKD2_k127_8177705_0 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000001364 191.0
HKD2_k127_8177705_1 Ras family - - - 0.000000000000000000000002088 117.0
HKD2_k127_8177705_2 - - - - 0.000000000004783 75.0
HKD2_k127_8185560_0 cellulose binding K15924 - 3.2.1.136 0.0000000000000008368 91.0
HKD2_k127_8198508_0 pathogenesis K21471,K21687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009065 255.0
HKD2_k127_8198508_1 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000002829 130.0
HKD2_k127_8202256_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 406.0
HKD2_k127_8202256_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 324.0
HKD2_k127_8202256_2 PFAM ABC transporter related K01990,K16907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 316.0
HKD2_k127_8202256_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 286.0
HKD2_k127_8202256_4 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.000000000000000000000000000000000000000000000000000003625 201.0
HKD2_k127_8202256_5 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000006088 142.0
HKD2_k127_8202256_6 Acetyltransferase (GNAT) domain - - - 0.0000000005478 69.0
HKD2_k127_8202256_7 ABC-2 type transporter K01992 - - 0.000000004199 69.0
HKD2_k127_8204958_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 331.0
HKD2_k127_8205230_0 acetyltransferase - - - 0.0000001645 59.0
HKD2_k127_8216040_0 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 344.0
HKD2_k127_8216040_1 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 307.0
HKD2_k127_8232415_0 type II secretion system protein K02283 - - 0.000000000811 65.0
HKD2_k127_8239535_0 Transcriptional regulator K02529,K07506 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 401.0
HKD2_k127_8239535_1 (GGDEF) domain - - - 0.0000000000000000000000000000000006349 151.0
HKD2_k127_8239535_2 Transcriptional regulator K02529,K07506 - - 0.00000000000000000000000000000003722 130.0
HKD2_k127_8244153_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000002574 242.0
HKD2_k127_8250286_0 polysaccharide catabolic process K05991 - 3.2.1.123 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 560.0
HKD2_k127_8261103_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 299.0
HKD2_k127_8261103_1 Glycosyltransferase like family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000006329 239.0
HKD2_k127_8261103_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000007762 179.0
HKD2_k127_8261103_3 abc-type fe3 -hydroxamate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000003578 160.0
HKD2_k127_8265447_0 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 322.0
HKD2_k127_8265447_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000002029 147.0
HKD2_k127_8265447_2 transporter K07238 - - 0.00000000000000000000000000000005099 130.0
HKD2_k127_8265447_3 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000001921 123.0
HKD2_k127_8267936_0 ABC transporter K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 287.0
HKD2_k127_8267936_1 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000007354 190.0
HKD2_k127_8267936_2 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000001792 128.0
HKD2_k127_8270371_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 - 5.3.1.25,5.3.1.3 2.767e-218 685.0
HKD2_k127_8270371_1 - - - - 0.0000001387 57.0
HKD2_k127_8275949_0 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000002706 70.0
HKD2_k127_8287382_0 IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000002619 171.0
HKD2_k127_8287382_1 Acetyltransferase (GNAT) domain - - - 0.0000000000003766 71.0
HKD2_k127_8288048_0 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000002609 139.0
HKD2_k127_8293396_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.89e-275 857.0
HKD2_k127_8293396_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002204 284.0
HKD2_k127_8296704_0 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000006174 254.0
HKD2_k127_8296704_1 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000001707 213.0
HKD2_k127_8296704_2 Sulfotransferase family - - - 0.00000000000000000000000000000000000003621 147.0
HKD2_k127_8301674_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 403.0
HKD2_k127_8301674_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 419.0
HKD2_k127_8301674_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 336.0
HKD2_k127_8301674_3 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005083 298.0
HKD2_k127_8301674_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005592 277.0
HKD2_k127_8301674_5 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000005101 214.0
HKD2_k127_8320967_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 608.0
HKD2_k127_8324196_0 PFAM Glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000002538 232.0
HKD2_k127_8324487_0 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 310.0
HKD2_k127_8324487_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000276 272.0
HKD2_k127_8324487_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001779 265.0
HKD2_k127_8324487_3 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000000000000000000000000000000000000001384 199.0
HKD2_k127_8324487_4 Redoxin - - - 0.00000000000000000003039 93.0
HKD2_k127_8325736_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 1.372e-201 638.0
HKD2_k127_8325736_1 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000004089 219.0
HKD2_k127_8325736_2 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000006115 158.0
HKD2_k127_8325736_3 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000007554 85.0
HKD2_k127_8326027_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000001353 99.0
HKD2_k127_8327861_0 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000001788 243.0
HKD2_k127_8327861_1 Ig-like domain from next to BRCA1 gene - - - 0.00000363 55.0
HKD2_k127_833172_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 445.0
HKD2_k127_833172_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000003158 231.0
HKD2_k127_833172_2 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002599 226.0
HKD2_k127_833172_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000008432 172.0
HKD2_k127_833172_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001308 76.0
HKD2_k127_833172_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000002625 72.0
HKD2_k127_833172_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0001071 44.0
HKD2_k127_8333004_0 ABC transporter K09691 - - 0.00000000000000000000000000000000000000000006245 168.0
HKD2_k127_8333004_1 Methyltransferase - - - 0.00000000000000000000000000001235 123.0
HKD2_k127_8335962_0 histidine kinase HAMP region domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001445 237.0
HKD2_k127_8335962_1 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000007702 212.0
HKD2_k127_8335962_2 Domain of unknown function (DUF362) - - - 0.00006392 55.0
HKD2_k127_8338765_0 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 480.0
HKD2_k127_8346207_0 TIGRFAM FeS assembly protein SufB K07033,K09014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 585.0
HKD2_k127_8346207_1 PFAM ABC transporter related K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 374.0
HKD2_k127_8346207_2 Winged helix-turn-helix DNA-binding - - - 0.00000003031 56.0
HKD2_k127_8350849_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1283.0
HKD2_k127_8350849_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000002099 211.0
HKD2_k127_8350849_2 Transposase - - - 0.0000000000000000000000000000000000000000000000000000102 196.0
HKD2_k127_8350849_3 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000000000000000000000000000000000000000000008336 172.0
HKD2_k127_8350849_4 Methyltransferase K15256 - - 0.0000000000000000000000000000000000000004165 158.0
HKD2_k127_8370055_0 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000004863 77.0
HKD2_k127_8384961_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 338.0
HKD2_k127_8384961_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000001891 168.0
HKD2_k127_840383_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001925 273.0
HKD2_k127_840383_1 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000000000000000000000000000000000000000000000000006937 205.0
HKD2_k127_8405269_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000003329 179.0
HKD2_k127_8406402_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000001629 174.0
HKD2_k127_8419661_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000003682 73.0
HKD2_k127_8422737_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 405.0
HKD2_k127_8422737_1 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000001563 196.0
HKD2_k127_8422737_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000009204 104.0
HKD2_k127_8429581_0 Nitroreductase family - - - 0.000000000000000000000000000000006887 131.0
HKD2_k127_8429581_1 repeat protein - - - 0.000000000000000000000009703 103.0
HKD2_k127_8429581_2 dihydrofolate reductase activity K00287 - 1.5.1.3 0.00000000001306 66.0
HKD2_k127_8449208_0 cellulose binding - - - 0.000000000000000000000000000002813 138.0
HKD2_k127_8461442_0 ABC-2 type transporter K01992 - - 0.000000000000133 84.0
HKD2_k127_8461442_1 ABC-2 family transporter protein K01992 - - 0.0000004328 61.0
HKD2_k127_8473944_0 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009486 295.0
HKD2_k127_8473944_1 PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000003562 164.0
HKD2_k127_8473944_2 LysM domain K07273,K22278 - 3.5.1.104 0.000000000006319 74.0
HKD2_k127_8477338_0 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000002466 195.0
HKD2_k127_8477338_1 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000008451 134.0
HKD2_k127_8480415_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000135 177.0
HKD2_k127_8480415_1 histidine kinase A domain protein - - - 0.000000000000000000000000000000008953 148.0
HKD2_k127_8482101_0 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000004366 59.0
HKD2_k127_8486855_0 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 468.0
HKD2_k127_8486855_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 420.0
HKD2_k127_8486855_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 404.0
HKD2_k127_8486855_3 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 380.0
HKD2_k127_8486855_4 Belongs to the glycosyl hydrolase 43 family K01198,K01209 - 3.2.1.37,3.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000001583 225.0
HKD2_k127_8492745_0 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000004846 151.0
HKD2_k127_8492745_1 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.00000000004998 64.0
HKD2_k127_8533955_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 502.0
HKD2_k127_8533955_1 periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 323.0
HKD2_k127_8534696_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
HKD2_k127_8534696_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001614 286.0
HKD2_k127_8534696_2 Domain of unknown function (DUF4129) - - - 0.000000000000000000000008179 112.0
HKD2_k127_8536886_0 Amino acid adenylation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 309.0
HKD2_k127_8536886_1 NMT1-like family K02051 - - 0.000000000000000000000000001837 125.0
HKD2_k127_8547381_0 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001192 255.0
HKD2_k127_8547381_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000003434 146.0
HKD2_k127_8557225_0 Belongs to the glycosyl hydrolase 35 family K12308 - 3.2.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 420.0
HKD2_k127_8557225_1 PFAM glycosyl transferase group 1 - - - 0.0000000000008926 80.0
HKD2_k127_8557225_2 Glycosyl transferase 4-like - - - 0.00000002563 63.0
HKD2_k127_8557225_3 Glycosyl transferase 4-like K19002 - 2.4.1.337 0.00000007891 65.0
HKD2_k127_8561212_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 393.0
HKD2_k127_8561212_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000105 203.0
HKD2_k127_8562327_0 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 558.0
HKD2_k127_8562327_1 PFAM periplasmic binding protein LacI transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000143 214.0
HKD2_k127_8576500_0 exodeoxyribonuclease I activity - - - 0.0000000000000000000000000000000000000000004783 162.0
HKD2_k127_8576500_1 sh3 domain protein K01448 - 3.5.1.28 0.0000000000000000006973 97.0
HKD2_k127_8576500_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000018 76.0
HKD2_k127_8585951_0 hydrolase, family 65, central catalytic K00691 - 2.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 439.0
HKD2_k127_8594137_0 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000001631 208.0
HKD2_k127_8594137_1 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000000000000000000000000000000000006653 196.0
HKD2_k127_8603826_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 372.0
HKD2_k127_8603826_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000001713 203.0
HKD2_k127_8604828_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000001587 221.0
HKD2_k127_8604828_1 Domain of unknown function (DUF4404) - - - 0.00000645 52.0
HKD2_k127_8609288_0 PFAM periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000959 170.0
HKD2_k127_8611820_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 361.0
HKD2_k127_8611820_1 Protein of unknown function (DUF1361) - - - 0.0000000000000000000000000000000002371 145.0
HKD2_k127_8611820_2 transmembrane transporter activity K08225 - - 0.000000005066 61.0
HKD2_k127_8614908_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 615.0
HKD2_k127_8614908_1 PFAM YbbR family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 300.0
HKD2_k127_8614908_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
HKD2_k127_8614908_3 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007134 283.0
HKD2_k127_862212_0 AdoMet dependent proline di-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000222 265.0
HKD2_k127_862212_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000004235 216.0
HKD2_k127_862212_2 - - - - 0.000000000000000000000000000000000000000000000000001411 194.0
HKD2_k127_862212_3 Belongs to the NUDIX hydrolase family - - - 0.000000001537 63.0
HKD2_k127_8625043_0 modification enzyme, MiaB family K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 383.0
HKD2_k127_8625043_1 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 289.0
HKD2_k127_8625793_0 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 462.0
HKD2_k127_8626723_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 369.0
HKD2_k127_8628238_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001823 283.0
HKD2_k127_8628238_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000005575 236.0
HKD2_k127_8643941_0 PFAM Aminotransferase, class I - - - 0.000000000000000004561 87.0
HKD2_k127_8643941_1 Acetyl xylan esterase (AXE1) - - - 0.000000000000007876 86.0
HKD2_k127_864856_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 8.721e-225 709.0
HKD2_k127_864856_1 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001193 248.0
HKD2_k127_864856_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000006742 142.0
HKD2_k127_864856_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000004895 61.0
HKD2_k127_8650203_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 426.0
HKD2_k127_8662577_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 589.0
HKD2_k127_8662577_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 0.0000000000006381 68.0
HKD2_k127_8671577_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 352.0
HKD2_k127_8671577_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 326.0
HKD2_k127_8671577_2 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 325.0
HKD2_k127_8693436_0 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000005863 164.0
HKD2_k127_8693436_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000001312 153.0
HKD2_k127_8693436_2 SMART helix-turn-helix domain protein K15539 - - 0.00000000000000000000000000000002064 140.0
HKD2_k127_8700015_0 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000002069 155.0
HKD2_k127_8700015_1 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000009891 98.0
HKD2_k127_8700015_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000001137 81.0
HKD2_k127_8701587_0 Protein of unknown function (DUF1349) K09702 - - 0.0000000000000000000000000000000000000000000000000000000000000000001003 237.0
HKD2_k127_8701587_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000001936 169.0
HKD2_k127_8707380_0 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000004265 231.0
HKD2_k127_8707380_1 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000002813 159.0
HKD2_k127_8717887_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 482.0
HKD2_k127_8717887_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 252.0
HKD2_k127_8717887_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000005428 173.0
HKD2_k127_8717887_3 LysM domain - - - 0.0000000000000000000000001756 115.0
HKD2_k127_8717887_4 YbaB/EbfC DNA-binding family K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000000000528 102.0
HKD2_k127_8717887_5 YacP-like NYN domain K06962 - - 0.0000000000000000002133 94.0
HKD2_k127_8720136_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001094 259.0
HKD2_k127_8722036_0 A G-specific adenine glycosylase K03574,K03575 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 337.0
HKD2_k127_8722036_1 Rad50 zinc hook motif K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 343.0
HKD2_k127_8722036_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03546,K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 303.0
HKD2_k127_8722036_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000018 168.0
HKD2_k127_8722036_4 diguanylate cyclase - - - 0.00000000000000000004642 93.0
HKD2_k127_8722969_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 421.0
HKD2_k127_8722969_1 DNA-binding transcription factor activity - - - 0.00000000000000000002356 96.0
HKD2_k127_872595_0 PFAM Thioredoxin domain K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002246 247.0
HKD2_k127_872595_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001119 237.0
HKD2_k127_872595_2 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000007235 202.0
HKD2_k127_872595_3 - - - - 0.0000000000000000000000000000000000003844 144.0
HKD2_k127_872595_4 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000007082 61.0
HKD2_k127_8729038_0 ATPase AAA-2 domain protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 426.0
HKD2_k127_8729038_1 Ig-like domain from next to BRCA1 gene - - - 0.000000000000001492 86.0
HKD2_k127_8743178_0 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003344 286.0
HKD2_k127_8743178_1 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000976 184.0
HKD2_k127_8743178_2 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000005279 182.0
HKD2_k127_8743178_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001465 78.0
HKD2_k127_8745727_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 602.0
HKD2_k127_8750484_0 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 458.0
HKD2_k127_8750484_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 449.0
HKD2_k127_8750484_2 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 324.0
HKD2_k127_8750484_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000005652 213.0
HKD2_k127_8750484_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000005336 181.0
HKD2_k127_8750484_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000001653 150.0
HKD2_k127_8750484_6 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000006802 147.0
HKD2_k127_8758933_0 PFAM regulatory protein LuxR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 422.0
HKD2_k127_8758933_1 ABC-type sugar transport system periplasmic component K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 423.0
HKD2_k127_876379_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 554.0
HKD2_k127_876379_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 243.0
HKD2_k127_876379_2 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000001017 125.0
HKD2_k127_876379_3 - - - - 0.000000000000000002053 93.0
HKD2_k127_876379_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000008378 87.0
HKD2_k127_8777980_0 - - - - 0.000000000000000000000000000000000000001274 164.0
HKD2_k127_8777980_1 Acetyltransferase (GNAT) domain - - - 0.00000596 55.0
HKD2_k127_8799868_0 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 3.273e-196 618.0
HKD2_k127_8799868_1 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
HKD2_k127_8799868_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000003908 163.0
HKD2_k127_8799868_3 - - - - 0.000003312 54.0
HKD2_k127_8804266_0 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001188 288.0
HKD2_k127_8804266_1 transferase activity, transferring glycosyl groups - - - 0.0000000000002911 72.0
HKD2_k127_8804266_2 PFAM Glycosyl transferase family 2 - - - 0.000000001106 61.0
HKD2_k127_8809540_0 hydrolase, family 3 K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000007313 229.0
HKD2_k127_8809540_1 Xylulokinase homolog (H. influenzae) K00854,K16732 GO:0003674,GO:0003824,GO:0004856,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0005997,GO:0005998,GO:0006063,GO:0006064,GO:0006082,GO:0006091,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019321,GO:0019323,GO:0019585,GO:0019637,GO:0019640,GO:0019752,GO:0031982,GO:0032787,GO:0043226,GO:0043227,GO:0043230,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044281,GO:0044282,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046395,GO:0046835,GO:0051167,GO:0070062,GO:0071704,GO:0072329,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576,GO:1903561 2.7.1.17 0.00000005178 57.0
HKD2_k127_8809540_2 FGGY family of carbohydrate kinases, C-terminal domain - - - 0.000007525 49.0
HKD2_k127_880957_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 514.0
HKD2_k127_880957_1 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000009737 162.0
HKD2_k127_8811506_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000618 258.0
HKD2_k127_8811506_1 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000000006511 128.0
HKD2_k127_8829367_0 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000002062 233.0
HKD2_k127_8842707_0 glycerophosphodiester transmembrane transport K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 323.0
HKD2_k127_8842707_1 PFAM extracellular solute-binding protein family 1 K02027 - - 0.0000000000000000001826 93.0
HKD2_k127_8843644_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.345e-200 631.0
HKD2_k127_8872451_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000001161 171.0
HKD2_k127_8872451_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000002175 118.0
HKD2_k127_8872451_2 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000009285 64.0
HKD2_k127_8874257_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000003977 225.0
HKD2_k127_8874257_1 TIGRFAM Transcriptional regulator, Rrf2 - - - 0.000000000000000000000004865 108.0
HKD2_k127_8883090_0 Belongs to the binding-protein-dependent transport system permease family K10544,K10547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 531.0
HKD2_k127_8883090_1 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 507.0
HKD2_k127_8883090_2 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10545,K10548 - 3.6.3.17 0.000000000000003992 76.0
HKD2_k127_8886841_0 Prolyl oligopeptidase family - - - 0.0000001034 64.0
HKD2_k127_8891391_0 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 0.0 1060.0
HKD2_k127_8891391_1 Belongs to the glycosyl hydrolase 2 family K01190 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009878 277.0
HKD2_k127_8891391_2 Protein of unknown function (DUF3788) - - - 0.0000000000000000000005106 104.0
HKD2_k127_8891391_3 Protein of unknown function (DUF493) K09158 - - 0.000000000004849 70.0
HKD2_k127_8914584_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 441.0
HKD2_k127_8914584_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000009012 77.0
HKD2_k127_8917578_0 PFAM natural resistance-associated macrophage protein K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 571.0
HKD2_k127_8917578_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000008844 202.0
HKD2_k127_8923867_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000002391 164.0
HKD2_k127_8923867_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000002007 63.0
HKD2_k127_8936036_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1785.0
HKD2_k127_8936036_1 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000482 191.0
HKD2_k127_8936036_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000001715 83.0
HKD2_k127_8950939_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 473.0
HKD2_k127_8950939_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 326.0
HKD2_k127_8950939_2 PFAM membrane-flanked domain - - - 0.000000000000000000000000000000000000000000000000000007674 198.0
HKD2_k127_8953378_0 Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 472.0
HKD2_k127_8964163_1 integral membrane protein K00728 - 2.4.1.109 0.000004096 59.0
HKD2_k127_8971998_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 512.0
HKD2_k127_8971998_1 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 410.0
HKD2_k127_8971998_2 Glycosyltransferase 28 domain K03715 - 2.4.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 376.0
HKD2_k127_8971998_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 371.0
HKD2_k127_8971998_4 SMART Nucleotide binding protein, PINc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 329.0
HKD2_k127_8971998_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000002316 172.0
HKD2_k127_8971998_6 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000000002437 97.0
HKD2_k127_8988099_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 556.0
HKD2_k127_8988099_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 447.0
HKD2_k127_8988099_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 329.0
HKD2_k127_8988099_3 PFAM secretion protein HlyD family protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000002322 213.0
HKD2_k127_900725_0 PFAM WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000645 251.0
HKD2_k127_900725_1 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000000000000000000000000001785 190.0
HKD2_k127_900725_2 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000001525 196.0
HKD2_k127_900725_3 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000000001944 166.0
HKD2_k127_900725_4 response to antibiotic - - - 0.0000000000000000000009293 102.0
HKD2_k127_9007420_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.117e-208 677.0
HKD2_k127_9007420_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 450.0
HKD2_k127_9007420_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000001057 85.0
HKD2_k127_9021419_0 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001629 216.0
HKD2_k127_9021419_1 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000134 197.0
HKD2_k127_9021419_2 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000002034 196.0
HKD2_k127_9021419_3 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000000005099 134.0
HKD2_k127_9027498_0 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 291.0
HKD2_k127_9027498_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002341 256.0
HKD2_k127_9027498_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006199 259.0
HKD2_k127_9027498_3 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000008346 207.0
HKD2_k127_9027498_4 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
HKD2_k127_9027498_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000398 178.0
HKD2_k127_9027498_6 - - - - 0.0000000000000000000000000000000000000000004249 162.0
HKD2_k127_9027498_7 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000002296 147.0
HKD2_k127_9027498_8 - - - - 0.00000000000000000000000000008084 128.0
HKD2_k127_9027498_9 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000003285 78.0
HKD2_k127_9053548_0 Belongs to the glycosyl hydrolase 28 family K01213 - 3.2.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 510.0
HKD2_k127_9053548_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 445.0
HKD2_k127_9053548_2 Fumarylacetoacetate (FAA) hydrolase family K16164 - 3.7.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 322.0
HKD2_k127_9053548_3 PFAM Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.0000000000000000000000000000000000000000000000000000000000004564 214.0
HKD2_k127_9063343_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 306.0
HKD2_k127_9063343_1 PFAM Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000004037 138.0
HKD2_k127_9070677_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 447.0
HKD2_k127_9070677_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 398.0
HKD2_k127_9072014_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005496 274.0
HKD2_k127_9072014_1 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000008499 225.0
HKD2_k127_9072014_2 transcriptional regulator - - - 0.000000000000000000000000000000003706 136.0
HKD2_k127_9079299_0 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000002555 261.0
HKD2_k127_9086392_0 Belongs to the glycosyl hydrolase 3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000004901 243.0
HKD2_k127_9086392_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000004091 89.0
HKD2_k127_9106620_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 459.0
HKD2_k127_9106620_1 PFAM DegV family protein - - - 0.000000000000000000000000000000000000000000000007998 184.0
HKD2_k127_9110710_0 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 430.0
HKD2_k127_9110710_1 Tetratricopeptide repeat-like domain - - - 0.000001738 58.0
HKD2_k127_911462_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 481.0
HKD2_k127_9120821_0 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000000003084 222.0
HKD2_k127_9120821_1 Encoded by - - - 0.00000000000000000000000000000004976 132.0
HKD2_k127_9121830_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 6.007e-215 676.0
HKD2_k127_9121830_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 342.0
HKD2_k127_9121830_2 bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006466 242.0
HKD2_k127_9142021_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 2.911e-214 673.0
HKD2_k127_9142021_1 endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000000000000001651 151.0
HKD2_k127_9163725_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 481.0
HKD2_k127_9163725_1 GtrA-like protein - - - 0.00000000000000000000000000001591 122.0
HKD2_k127_9168732_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 335.0
HKD2_k127_9168732_1 Protein of unknown function (DUF559) - - - 0.000000000000000000000008603 115.0
HKD2_k127_9168732_2 Acetyltransferase K03829 - - 0.0000000000005222 69.0
HKD2_k127_9174045_0 PFAM PfkB domain protein K16328 - 2.7.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000004255 273.0
HKD2_k127_9174045_1 Magnesium chelatase, subunit ChlI C-terminal K06400,K07391 - - 0.00000000000000000000000000000000000000000000000396 175.0
HKD2_k127_9180023_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.492e-196 625.0
HKD2_k127_9180023_1 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 402.0
HKD2_k127_9180023_2 phosphoribosylaminoimidazole carboxylase activity K01923 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009719,GO:0009725,GO:0009733,GO:0009987,GO:0010033,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000008521 180.0
HKD2_k127_9188726_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004844 273.0
HKD2_k127_9188726_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.000000000000000008437 90.0
HKD2_k127_9194610_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000000000000000000000000000000000000002085 190.0
HKD2_k127_9194610_1 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.00000008907 55.0
HKD2_k127_9196085_0 DNA binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 515.0
HKD2_k127_9196085_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 461.0
HKD2_k127_9196085_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000253 224.0
HKD2_k127_9196085_3 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000006946 110.0
HKD2_k127_9197187_0 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000000000009714 153.0
HKD2_k127_9197187_1 MFS_1 like family - - - 0.00000000000000000000000009478 120.0
HKD2_k127_9203127_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 1.205e-277 862.0
HKD2_k127_9208839_0 protein methyltransferase activity K11434,K15984,K20421 - 2.1.1.242,2.1.1.303,2.1.1.319 0.00000000000000000000000000000000000000000000000000000000000000328 228.0
HKD2_k127_9212089_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 392.0
HKD2_k127_9212089_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000007695 109.0
HKD2_k127_9225116_0 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.000000000000000000000000000000000000000000000000000000000000000000009141 248.0
HKD2_k127_9225116_1 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000002016 207.0
HKD2_k127_9225116_2 self proteolysis - - - 0.000000001122 69.0
HKD2_k127_9225116_3 acyl carrier protein - - - 0.0000122 50.0
HKD2_k127_9230249_0 - - - - 0.0000004142 59.0
HKD2_k127_9236437_0 ABC transporter K01990,K11050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 256.0
HKD2_k127_9236437_1 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000003533 134.0
HKD2_k127_9236437_2 DNA methylase - - - 0.00000000002106 76.0
HKD2_k127_9236437_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000001301 51.0
HKD2_k127_9237228_0 penicillin binding K05367 - 2.4.1.129 0.0000000000001383 84.0
HKD2_k127_923967_0 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 305.0
HKD2_k127_923967_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000009494 256.0
HKD2_k127_923967_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000132 217.0
HKD2_k127_923967_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000002166 197.0
HKD2_k127_923967_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000001027 185.0
HKD2_k127_923967_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000004805 64.0
HKD2_k127_9256852_0 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 595.0
HKD2_k127_9256852_1 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000003879 233.0
HKD2_k127_9280496_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 363.0
HKD2_k127_9280496_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000002641 133.0
HKD2_k127_9280496_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000001663 100.0
HKD2_k127_9280504_0 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000003699 169.0
HKD2_k127_9284030_0 polysaccharide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 526.0
HKD2_k127_9294869_0 glutamate synthase alpha subunit domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 443.0
HKD2_k127_929608_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 359.0
HKD2_k127_929608_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000003297 231.0
HKD2_k127_929608_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000008232 143.0
HKD2_k127_9307823_0 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 447.0
HKD2_k127_9307823_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003138 237.0
HKD2_k127_9326741_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 507.0
HKD2_k127_9326741_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 399.0
HKD2_k127_9326741_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004101 279.0
HKD2_k127_935208_0 Polysaccharide deacetylase - - - 0.00000000000000000226 97.0
HKD2_k127_935208_1 polysaccharide deacetylase K22278 - 3.5.1.104 0.0006113 50.0
HKD2_k127_9353339_0 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002507 254.0
HKD2_k127_9353339_1 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000002532 103.0
HKD2_k127_9368746_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 398.0
HKD2_k127_9368746_1 TIGRFAM RarD protein, DMT superfamily transporter K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 305.0
HKD2_k127_9368746_2 Belongs to the TtcA family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000006186 245.0
HKD2_k127_9368746_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000455 235.0
HKD2_k127_9368746_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000002599 152.0
HKD2_k127_9368746_5 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000267 148.0
HKD2_k127_9368746_6 - - - - 0.000000000000000000000000000000000000008117 157.0
HKD2_k127_9369565_0 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000000006285 140.0
HKD2_k127_9369565_1 Ig-like domain from next to BRCA1 gene - - - 0.000000000000215 83.0
HKD2_k127_9369565_2 chromosome 6 open reading frame 106 - GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919 - 0.00000000004264 76.0
HKD2_k127_9400979_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 320.0
HKD2_k127_9400979_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000001115 225.0
HKD2_k127_9406033_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 452.0
HKD2_k127_9406033_1 adenosine deaminase K01488,K21053 - 3.5.4.2,3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 397.0
HKD2_k127_9406033_2 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001185 218.0
HKD2_k127_9406033_3 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.0000000000000003909 88.0
HKD2_k127_9406033_4 ATP-grasp domain K01955 - 6.3.5.5 0.000000000007843 67.0
HKD2_k127_9416376_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 346.0
HKD2_k127_9416376_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005429 279.0
HKD2_k127_9416376_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000000000000000000008392 221.0
HKD2_k127_9430415_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005468 281.0
HKD2_k127_9430415_1 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003812 264.0
HKD2_k127_9449417_0 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 453.0
HKD2_k127_9449417_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 334.0
HKD2_k127_9453121_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 494.0
HKD2_k127_9453121_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005189 258.0
HKD2_k127_9453121_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000004974 252.0
HKD2_k127_9453121_3 PFAM Peptidase C1A, papain - - - 0.0000000000000000001489 102.0
HKD2_k127_9462478_0 ABC-2 family transporter protein K01992 - - 0.000000000000001346 89.0
HKD2_k127_9463298_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 460.0
HKD2_k127_9483776_0 Domain of unknown function (DUF4832) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001193 274.0
HKD2_k127_9483776_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000009588 201.0
HKD2_k127_9505944_0 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 406.0
HKD2_k127_9505944_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000001337 181.0
HKD2_k127_9505944_2 ABC transporter permease K01992 - - 0.0004035 45.0
HKD2_k127_9531720_0 Immunoglobulin-like domain of bacterial spore germination - - - 0.00000000000000000000004947 106.0
HKD2_k127_9531720_1 Cytochrome oxidase complex assembly protein 1 - - - 0.00000000000000000009498 94.0
HKD2_k127_9531720_2 Protein of unknown function DUF111 K06898,K09121 - 4.99.1.12 0.00000000000000000169 88.0
HKD2_k127_9531720_3 Cytochrome oxidase complex assembly protein 1 - - - 0.00000000000000002399 87.0
HKD2_k127_9531720_4 Domain of unknown function (DUF4190) - - - 0.000000000008427 71.0
HKD2_k127_9542478_0 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 360.0
HKD2_k127_9542478_1 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 296.0
HKD2_k127_9544835_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 1.325e-197 650.0
HKD2_k127_9544835_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 442.0
HKD2_k127_9544835_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 400.0
HKD2_k127_9544835_3 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 382.0
HKD2_k127_9544835_4 Belongs to the SEDS family K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 323.0
HKD2_k127_9544835_5 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.0000000000000000000000000000000000000000000000000000000003596 210.0
HKD2_k127_9544835_6 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000001078 199.0
HKD2_k127_9544835_7 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.000000000001157 74.0
HKD2_k127_9544835_8 Rod shape-determining protein K03571 - - 0.0000001014 60.0
HKD2_k127_9544835_9 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0002559 46.0
HKD2_k127_9575454_0 Two component transcriptional regulator, winged helix family K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 285.0
HKD2_k127_9575454_1 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000003088 235.0
HKD2_k127_9575454_2 OsmC-like protein K07397 - - 0.0000000000000000000000006107 108.0
HKD2_k127_9575454_3 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000002125 111.0
HKD2_k127_9584016_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 508.0
HKD2_k127_9584016_1 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000464 286.0
HKD2_k127_9584016_3 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000001228 76.0
HKD2_k127_9591558_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 409.0
HKD2_k127_9591558_1 dephospho-CoA kinase activity K00859,K08309,K10563 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000004304 175.0
HKD2_k127_9591558_2 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000001923 128.0
HKD2_k127_9591558_3 polysaccharide deacetylase - - - 0.000000000000002 87.0
HKD2_k127_9591558_4 PFAM Methyltransferase type 11 - - - 0.00000000004132 72.0
HKD2_k127_9601962_0 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 413.0
HKD2_k127_9620040_0 aldehyde K00131 - 1.2.1.9 3.083e-202 641.0
HKD2_k127_9620040_1 conserved protein (DUF2174) - - - 0.0000000000000000000000000000000000000000000000000000007388 198.0
HKD2_k127_9627715_0 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001554 216.0
HKD2_k127_9632683_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 390.0
HKD2_k127_9632683_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 297.0
HKD2_k127_9632683_2 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009776 241.0
HKD2_k127_9649598_0 ABC1 family - - - 0.0000000000000000000000000000000000000000003969 162.0
HKD2_k127_9649598_1 Pfam SNARE associated Golgi protein - - - 0.0000004912 59.0
HKD2_k127_9654908_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 309.0
HKD2_k127_9654908_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 294.0
HKD2_k127_9658086_0 - K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 584.0
HKD2_k127_9658086_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 322.0
HKD2_k127_9658086_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000002153 220.0
HKD2_k127_9658086_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000001429 154.0
HKD2_k127_9658086_5 HMGL-like K01666 - 4.1.3.39 0.000001495 49.0
HKD2_k127_9658404_0 Glycosyl hydrolase family 115 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 507.0
HKD2_k127_9658404_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 432.0
HKD2_k127_9665095_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000005549 192.0
HKD2_k127_9665095_1 - - - - 0.000000000000000000000002375 120.0
HKD2_k127_9669691_0 - - - - 0.000000000000000000000001941 106.0
HKD2_k127_9669691_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000006154 88.0
HKD2_k127_9673384_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 372.0
HKD2_k127_9673384_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.0000000000000000000000000000000000008361 142.0
HKD2_k127_9679699_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 464.0
HKD2_k127_9679699_1 Hydrogenase accessory protein HypB K03189,K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 308.0
HKD2_k127_9679699_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000002832 108.0
HKD2_k127_9686824_0 heme binding K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005432 264.0
HKD2_k127_9686824_1 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001156 263.0
HKD2_k127_9686824_2 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000003291 130.0
HKD2_k127_9686824_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000003727 110.0
HKD2_k127_9728512_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 285.0
HKD2_k127_9728512_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000001822 121.0
HKD2_k127_9737236_0 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 398.0
HKD2_k127_9745663_0 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 332.0
HKD2_k127_9745663_1 Protein of unknown function (DUF559) - - - 0.0000000000000000000004411 102.0
HKD2_k127_9788218_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 306.0
HKD2_k127_9788218_1 Protein of unknown function (DUF3795) - - - 0.000000000000000000000002874 107.0
HKD2_k127_9792006_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 482.0
HKD2_k127_9800644_0 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000004411 147.0
HKD2_k127_9800644_1 Protein of unknown function (DUF521) K09123 - - 0.00000003556 57.0
HKD2_k127_9810636_0 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 294.0
HKD2_k127_981363_0 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000003777 235.0
HKD2_k127_981363_1 enterobactin catabolic process K07214 - - 0.0000000000000000002477 98.0
HKD2_k127_981363_2 Abortive infection protein K07052 - - 0.000000000006312 75.0
HKD2_k127_9829831_0 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 5.708e-216 679.0
HKD2_k127_9829831_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
HKD2_k127_9829831_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000236 158.0
HKD2_k127_9829831_3 SdpI/YhfL protein family - - - 0.000000001357 64.0
HKD2_k127_985138_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 347.0
HKD2_k127_985138_1 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.000000000000000000005684 95.0
HKD2_k127_985138_2 PFAM ABC-2 type transporter K01992 - - 0.00004768 52.0
HKD2_k127_9879644_0 GAF domain - - - 0.000000007603 66.0
HKD2_k127_9881827_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 460.0
HKD2_k127_9881827_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000003301 144.0
HKD2_k127_9882759_0 Transposase IS200 like - - - 0.00000004638 62.0
HKD2_k127_9889732_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 335.0
HKD2_k127_9889732_1 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000004814 114.0
HKD2_k127_9889732_2 Protein of unknown function (DUF503) K09764 - - 0.000000000001043 72.0
HKD2_k127_9894456_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.774e-220 692.0
HKD2_k127_9894456_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 296.0
HKD2_k127_9894456_2 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000009787 106.0
HKD2_k127_9894456_3 Acyltransferase family - - - 0.0004623 46.0
HKD2_k127_9911527_0 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0048037,GO:0048038,GO:0048039,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008762 597.0
HKD2_k127_9911527_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001263 259.0
HKD2_k127_9911527_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.0000000000000000003168 92.0
HKD2_k127_991413_0 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 542.0
HKD2_k127_991413_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 474.0
HKD2_k127_991413_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 323.0
HKD2_k127_9935413_0 Domain of unknown function (DUF4352) - - - 0.00001326 55.0
HKD2_k127_9938118_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000584 260.0
HKD2_k127_9941914_0 carbohydrate transport K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 501.0
HKD2_k127_9941914_1 protein secretion by the type VII secretion system - - - 0.00000005116 59.0
HKD2_k127_9943878_1 - - - - 0.0000005465 61.0
HKD2_k127_9952937_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 404.0
HKD2_k127_9952937_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 302.0
HKD2_k127_9952937_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 277.0
HKD2_k127_9952937_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000002759 196.0