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Overview

ID MAG01811
Name HKD2_bin.67
Sample SMP0047
Taxonomy
Kingdom Bacteria
Phylum Bacteroidota_A
Class UBA10030
Order UBA10030
Family UBA6906
Genus UBA6906
Species
Assembly information
Completeness (%) 96.25
Contamination (%) 0.22
GC content (%) 60.0
N50 (bp) 126,448
Genome size (bp) 3,458,943

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2647

Gene name Description KEGG GOs EC E-value Score Sequence
HKD2_k127_1068391_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 1.962e-206 652.0
HKD2_k127_1328989_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 582.0
HKD2_k127_1328989_1 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 306.0
HKD2_k127_1328989_2 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000001878 207.0
HKD2_k127_1328989_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.0000000000000000000000000000002721 137.0
HKD2_k127_1514749_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1237.0
HKD2_k127_1514749_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1157.0
HKD2_k127_1514749_11 Flavin containing amine oxidoreductase K09835,K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 577.0
HKD2_k127_1514749_12 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 570.0
HKD2_k127_1514749_13 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 521.0
HKD2_k127_1514749_14 Alpha-L-rhamnosidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 522.0
HKD2_k127_1514749_15 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 482.0
HKD2_k127_1514749_16 C4-dicarboxylate anaerobic carrier - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 486.0
HKD2_k127_1514749_17 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 463.0
HKD2_k127_1514749_18 Bacterial regulatory protein, Fis family K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 464.0
HKD2_k127_1514749_19 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 452.0
HKD2_k127_1514749_2 Response regulator, receiver K01007 - 2.7.9.2 0.0 1135.0
HKD2_k127_1514749_20 Belongs to the mandelate racemase muconate lactonizing enzyme family K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 444.0
HKD2_k127_1514749_21 phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 448.0
HKD2_k127_1514749_22 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 443.0
HKD2_k127_1514749_23 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 446.0
HKD2_k127_1514749_24 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 380.0
HKD2_k127_1514749_25 Serine threonine protein kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 403.0
HKD2_k127_1514749_26 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 366.0
HKD2_k127_1514749_27 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 359.0
HKD2_k127_1514749_28 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009835 330.0
HKD2_k127_1514749_29 metallocarboxypeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 310.0
HKD2_k127_1514749_3 family 2 sugar binding - - - 0.0 1090.0
HKD2_k127_1514749_30 COG1175 ABC-type sugar transport systems permease components K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 293.0
HKD2_k127_1514749_31 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005289 296.0
HKD2_k127_1514749_32 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001196 283.0
HKD2_k127_1514749_33 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001208 282.0
HKD2_k127_1514749_34 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003772 261.0
HKD2_k127_1514749_35 COGs COG0395 ABC-type sugar transport system permease component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001656 261.0
HKD2_k127_1514749_36 Putative cyclase K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005756 254.0
HKD2_k127_1514749_37 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000002554 252.0
HKD2_k127_1514749_38 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000001234 256.0
HKD2_k127_1514749_39 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002359 248.0
HKD2_k127_1514749_4 TonB-dependent receptor - - - 8.153e-291 920.0
HKD2_k127_1514749_40 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007259 226.0
HKD2_k127_1514749_42 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000004955 224.0
HKD2_k127_1514749_43 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000004791 224.0
HKD2_k127_1514749_44 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000001276 207.0
HKD2_k127_1514749_45 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001851 191.0
HKD2_k127_1514749_46 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000003695 192.0
HKD2_k127_1514749_47 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000000000000000000000000000000000000000000000003041 183.0
HKD2_k127_1514749_48 glyoxalase III activity K13653 - - 0.000000000000000000000000000000000000000000000001407 177.0
HKD2_k127_1514749_49 - - - - 0.00000000000000000000000000000000000000000000002214 181.0
HKD2_k127_1514749_5 FMN binding - - - 2.365e-242 758.0
HKD2_k127_1514749_50 - - - - 0.0000000000000000000000000000000000000000000001505 185.0
HKD2_k127_1514749_51 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000001518 172.0
HKD2_k127_1514749_52 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000004504 179.0
HKD2_k127_1514749_53 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000549 181.0
HKD2_k127_1514749_54 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000004864 172.0
HKD2_k127_1514749_55 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000104 171.0
HKD2_k127_1514749_56 - - - - 0.0000000000000000000000000000000000000000001356 175.0
HKD2_k127_1514749_57 ABC-type sugar transport system, periplasmic component K02027 - - 0.000000000000000000000000000000000000000002654 172.0
HKD2_k127_1514749_58 - - - - 0.0000000000000000000000000000000000000005429 162.0
HKD2_k127_1514749_59 Domain of unknown function (DUF1905) - - - 0.00000000000000000000000000000000000003442 151.0
HKD2_k127_1514749_6 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 4.994e-235 765.0
HKD2_k127_1514749_60 gluconolactonase activity - - - 0.0000000000000000000000000000000000435 149.0
HKD2_k127_1514749_61 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000006443 141.0
HKD2_k127_1514749_62 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000001431 139.0
HKD2_k127_1514749_63 PFAM oxidoreductase - - - 0.0000000000000000000000000000002871 136.0
HKD2_k127_1514749_64 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000007414 128.0
HKD2_k127_1514749_65 membrane-bound metal-dependent K07038 - - 0.000000000000000000000000001274 129.0
HKD2_k127_1514749_66 - - - - 0.000000000000000000000000001669 130.0
HKD2_k127_1514749_67 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000006336 123.0
HKD2_k127_1514749_68 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000002434 109.0
HKD2_k127_1514749_7 GDSL-like Lipase/Acylhydrolase family - - - 1.921e-219 702.0
HKD2_k127_1514749_70 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000004542 109.0
HKD2_k127_1514749_71 - - - - 0.0000000000000000000004577 113.0
HKD2_k127_1514749_73 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.0000000000000000001245 102.0
HKD2_k127_1514749_74 META domain - - - 0.0000000000000000001913 94.0
HKD2_k127_1514749_75 Type II secretory pathway component ExeA - - - 0.0000000000000000002317 101.0
HKD2_k127_1514749_76 - - - - 0.0000000000000000005488 89.0
HKD2_k127_1514749_77 - - - - 0.00000000000000000208 95.0
HKD2_k127_1514749_78 peptidyl-tyrosine sulfation - - - 0.000000000000000004299 98.0
HKD2_k127_1514749_79 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000000000976 88.0
HKD2_k127_1514749_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 9.66e-202 635.0
HKD2_k127_1514749_80 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.000000000001504 68.0
HKD2_k127_1514749_81 - - - - 0.000000000007987 75.0
HKD2_k127_1514749_83 cytochrome c peroxidase - - - 0.0000000001254 65.0
HKD2_k127_1514749_84 methylglyoxal synthase K01734 - 4.2.3.3 0.0000001375 53.0
HKD2_k127_1514749_85 Putative zinc-finger - - - 0.000001831 56.0
HKD2_k127_1514749_86 Antibiotic biosynthesis monooxygenase - - - 0.000007294 54.0
HKD2_k127_1514749_9 FAD dependent oxidoreductase - - - 2.777e-201 640.0
HKD2_k127_15605_0 polysaccharide deacetylase K01179 - 3.2.1.4 2.105e-320 1001.0
HKD2_k127_15605_1 Enoyl-(Acyl carrier protein) reductase K00216 - 1.3.1.28 9.244e-242 766.0
HKD2_k127_15605_10 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 443.0
HKD2_k127_15605_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 411.0
HKD2_k127_15605_12 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 384.0
HKD2_k127_15605_13 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 359.0
HKD2_k127_15605_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 364.0
HKD2_k127_15605_15 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 350.0
HKD2_k127_15605_16 Domain of unknown function (DUF4432) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 346.0
HKD2_k127_15605_17 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 341.0
HKD2_k127_15605_18 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 322.0
HKD2_k127_15605_19 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 312.0
HKD2_k127_15605_2 - - - - 1.391e-224 719.0
HKD2_k127_15605_20 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
HKD2_k127_15605_21 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 301.0
HKD2_k127_15605_22 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004805 287.0
HKD2_k127_15605_23 dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001769 274.0
HKD2_k127_15605_24 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008205 268.0
HKD2_k127_15605_25 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000006429 274.0
HKD2_k127_15605_26 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000006396 268.0
HKD2_k127_15605_27 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001939 263.0
HKD2_k127_15605_28 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000007394 255.0
HKD2_k127_15605_29 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000004947 235.0
HKD2_k127_15605_3 Heparinase II/III-like protein - - - 2.36e-213 682.0
HKD2_k127_15605_30 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000003255 194.0
HKD2_k127_15605_31 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000009302 188.0
HKD2_k127_15605_32 Belongs to the carbohydrate kinase PfkB family K00882,K00917,K16370 - 2.7.1.11,2.7.1.144,2.7.1.56 0.00000000000000000000000000000000000000000000005599 181.0
HKD2_k127_15605_33 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000007815 178.0
HKD2_k127_15605_34 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000004445 176.0
HKD2_k127_15605_35 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000009164 172.0
HKD2_k127_15605_36 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000008474 161.0
HKD2_k127_15605_37 regulatory protein IclR - - - 0.00000000000000000000000000000000005309 144.0
HKD2_k127_15605_38 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000236 120.0
HKD2_k127_15605_39 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000002886 123.0
HKD2_k127_15605_4 Glycosyl Hydrolase Family 88 - - - 3.163e-210 668.0
HKD2_k127_15605_40 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000008982 122.0
HKD2_k127_15605_41 Phytanoyl-CoA dioxygenase - - - 0.00000000000000000000001004 109.0
HKD2_k127_15605_42 WD40 domain protein beta Propeller K03641 - - 0.0000000000000000002122 100.0
HKD2_k127_15605_43 Carbon-nitrogen hydrolase - - - 0.0000000000000000002312 102.0
HKD2_k127_15605_44 cheY-homologous receiver domain K03413 - - 0.000000000000002292 82.0
HKD2_k127_15605_45 amidohydrolase K07045 - - 0.00000000001595 77.0
HKD2_k127_15605_46 Glycosyl hydrolases family 15 - - - 0.0000003257 64.0
HKD2_k127_15605_47 F5/8 type C domain - - - 0.00008016 56.0
HKD2_k127_15605_48 COG3459 Cellobiose phosphorylase - - - 0.0001837 55.0
HKD2_k127_15605_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 4.205e-205 654.0
HKD2_k127_15605_6 Glycogen debranching enzyme - - - 2.391e-201 640.0
HKD2_k127_15605_7 Alpha mannosidase, middle domain K01191,K15524,K16869 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 2.3.1.204,3.2.1.170,3.2.1.24 6.334e-201 656.0
HKD2_k127_15605_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 613.0
HKD2_k127_15605_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 461.0
HKD2_k127_195447_0 polyketide synthase K21792 - - 8.999e-255 822.0
HKD2_k127_2085665_0 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 407.0
HKD2_k127_2085665_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000001233 61.0
HKD2_k127_2589435_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 516.0
HKD2_k127_2589435_1 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000004138 256.0
HKD2_k127_2589435_2 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000004737 221.0
HKD2_k127_2589435_3 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000005139 117.0
HKD2_k127_2589435_4 - - - - 0.000000001467 72.0
HKD2_k127_2597780_0 transport - - - 0.0 1060.0
HKD2_k127_2597780_1 fibronectin type III domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 589.0
HKD2_k127_2597780_10 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.00000000000000000000000006419 125.0
HKD2_k127_2597780_11 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.000000000000000000000001083 110.0
HKD2_k127_2597780_12 nucleotide catabolic process K01081,K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000005741 98.0
HKD2_k127_2597780_13 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000001364 71.0
HKD2_k127_2597780_14 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000004624 58.0
HKD2_k127_2597780_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 565.0
HKD2_k127_2597780_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 441.0
HKD2_k127_2597780_4 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 333.0
HKD2_k127_2597780_5 Asparaginase, N-terminal K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006562 251.0
HKD2_k127_2597780_6 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002359 264.0
HKD2_k127_2597780_7 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000000000000000000000000000000000000000101 234.0
HKD2_k127_2597780_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000377 229.0
HKD2_k127_2597780_9 - - - - 0.00000000000000000000000000000000000000000000000004204 189.0
HKD2_k127_2626540_0 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 461.0
HKD2_k127_2626540_1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 445.0
HKD2_k127_2626540_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000008097 208.0
HKD2_k127_2626540_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000001063 171.0
HKD2_k127_2626540_4 NlpC/P60 family - - - 0.00000000000000000000000000000001826 136.0
HKD2_k127_2626540_5 GGDEF domain K02478 - 2.7.13.3 0.00000000000000000000000000003048 129.0
HKD2_k127_2686226_0 Glycosyltransferase family 36 K18675 - 2.4.1.280 0.0 1251.0
HKD2_k127_2686226_1 glycoside hydrolase family 38 K01191 - 3.2.1.24 0.0 1144.0
HKD2_k127_2686226_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 434.0
HKD2_k127_2686226_11 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 427.0
HKD2_k127_2686226_12 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 429.0
HKD2_k127_2686226_13 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001186 257.0
HKD2_k127_2686226_14 Glyco_18 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005382 262.0
HKD2_k127_2686226_15 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000003041 226.0
HKD2_k127_2686226_16 Alpha-1,2-mannosidase - - - 0.00000000000000000000000000000000006611 156.0
HKD2_k127_2686226_17 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.000000000001308 82.0
HKD2_k127_2686226_2 deoxyhypusine monooxygenase activity - - - 3.416e-237 773.0
HKD2_k127_2686226_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.847e-198 625.0
HKD2_k127_2686226_4 Domain of unknown function (DUF4838) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 621.0
HKD2_k127_2686226_5 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 584.0
HKD2_k127_2686226_6 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 488.0
HKD2_k127_2686226_7 Glycosyl hydrolases family 38 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 496.0
HKD2_k127_2686226_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 478.0
HKD2_k127_2686226_9 PFAM AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 472.0
HKD2_k127_2883294_0 TonB-dependent receptor - - - 0.0 1062.0
HKD2_k127_2883294_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 8.483e-321 992.0
HKD2_k127_2883294_10 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 516.0
HKD2_k127_2883294_11 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K03205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 521.0
HKD2_k127_2883294_12 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 488.0
HKD2_k127_2883294_13 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 466.0
HKD2_k127_2883294_14 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 458.0
HKD2_k127_2883294_15 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 462.0
HKD2_k127_2883294_16 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 414.0
HKD2_k127_2883294_17 PFAM major facilitator superfamily MFS_1 K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 416.0
HKD2_k127_2883294_18 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 398.0
HKD2_k127_2883294_19 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 383.0
HKD2_k127_2883294_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.64e-267 840.0
HKD2_k127_2883294_20 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 409.0
HKD2_k127_2883294_21 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 369.0
HKD2_k127_2883294_22 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 362.0
HKD2_k127_2883294_23 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 356.0
HKD2_k127_2883294_24 TIGRFAM N-terminal double-transmembrane domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 352.0
HKD2_k127_2883294_25 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 330.0
HKD2_k127_2883294_26 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 326.0
HKD2_k127_2883294_27 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 327.0
HKD2_k127_2883294_28 transferase activity, transferring alkyl or aryl (other than methyl) groups K00806,K14215,K21273 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008834,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0050347,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.86,2.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
HKD2_k127_2883294_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 326.0
HKD2_k127_2883294_3 membrane organization K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 7.625e-264 834.0
HKD2_k127_2883294_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 321.0
HKD2_k127_2883294_31 iron ion homeostasis K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003157 289.0
HKD2_k127_2883294_32 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002208 276.0
HKD2_k127_2883294_33 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002226 278.0
HKD2_k127_2883294_34 inositol monophosphate 1-phosphatase activity K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000457 279.0
HKD2_k127_2883294_35 ROK family K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002145 272.0
HKD2_k127_2883294_36 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001901 284.0
HKD2_k127_2883294_37 cellular water homeostasis K05802,K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009429 259.0
HKD2_k127_2883294_38 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002337 259.0
HKD2_k127_2883294_39 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005966 253.0
HKD2_k127_2883294_4 serine-type D-Ala-D-Ala carboxypeptidase activity K05366 - 2.4.1.129,3.4.16.4 3.203e-221 708.0
HKD2_k127_2883294_40 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000007032 242.0
HKD2_k127_2883294_41 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001972 255.0
HKD2_k127_2883294_42 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000003117 240.0
HKD2_k127_2883294_43 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000186 237.0
HKD2_k127_2883294_44 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000001004 234.0
HKD2_k127_2883294_45 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000002655 229.0
HKD2_k127_2883294_46 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000001047 214.0
HKD2_k127_2883294_47 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000004421 217.0
HKD2_k127_2883294_48 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000006673 227.0
HKD2_k127_2883294_49 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000001147 195.0
HKD2_k127_2883294_5 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity K02372,K02535,K13599,K16363 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 3.5.1.108,4.2.1.59 1.387e-217 683.0
HKD2_k127_2883294_50 unfolded protein binding K06142 - - 0.00000000000000000000000000000000000000000000000001663 184.0
HKD2_k127_2883294_51 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000003425 185.0
HKD2_k127_2883294_52 DinB family - - - 0.0000000000000000000000000000000000000000000000007619 179.0
HKD2_k127_2883294_53 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000000000000000000000000001066 182.0
HKD2_k127_2883294_54 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000006907 185.0
HKD2_k127_2883294_55 - - - - 0.00000000000000000000000000000000000000000000001205 179.0
HKD2_k127_2883294_56 nUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000003932 177.0
HKD2_k127_2883294_57 succinate dehydrogenase K00241 - - 0.0000000000000000000000000000000000000000000001964 177.0
HKD2_k127_2883294_58 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000003583 168.0
HKD2_k127_2883294_59 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000005856 175.0
HKD2_k127_2883294_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 604.0
HKD2_k127_2883294_60 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000004883 166.0
HKD2_k127_2883294_62 YbaB/EbfC DNA-binding family K09747 - - 0.00000000000000000000000000000008356 127.0
HKD2_k127_2883294_63 - - - - 0.000000000000000000000000001471 122.0
HKD2_k127_2883294_64 peptide deformylase activity K01462 - 3.5.1.88 0.000000000000000000000000002261 113.0
HKD2_k127_2883294_65 EamA-like transporter family - - - 0.000000000000000000000129 112.0
HKD2_k127_2883294_67 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000002984 102.0
HKD2_k127_2883294_68 DNA-binding helix-turn-helix protein K01356 - 3.4.21.88 0.00000000000000000000775 101.0
HKD2_k127_2883294_69 - - - - 0.00000000000000000002004 93.0
HKD2_k127_2883294_7 membrane organization K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 612.0
HKD2_k127_2883294_70 - - - - 0.0000000000002081 83.0
HKD2_k127_2883294_71 CarboxypepD_reg-like domain - - - 0.0000004655 57.0
HKD2_k127_2883294_74 Helix-turn-helix domain - - - 0.0003158 49.0
HKD2_k127_2883294_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 562.0
HKD2_k127_2883294_9 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 512.0
HKD2_k127_3097812_0 Two component regulator propeller K19694 - - 0.00000000000000000000000000000000000005611 160.0
HKD2_k127_3125836_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1212.0
HKD2_k127_3125836_1 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 5.206e-278 878.0
HKD2_k127_3125836_10 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 488.0
HKD2_k127_3125836_11 POT family K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 462.0
HKD2_k127_3125836_12 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 431.0
HKD2_k127_3125836_13 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 397.0
HKD2_k127_3125836_14 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 366.0
HKD2_k127_3125836_15 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 362.0
HKD2_k127_3125836_16 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 349.0
HKD2_k127_3125836_17 N-Acetylmuramoyl-L-alanine amidase K01176,K01448,K06385 - 3.2.1.1,3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 367.0
HKD2_k127_3125836_18 UDPglucose--hexose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 310.0
HKD2_k127_3125836_19 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 301.0
HKD2_k127_3125836_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 1.048e-239 775.0
HKD2_k127_3125836_20 Cell wall-associated hydrolase (invasion-associated protein) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004427 290.0
HKD2_k127_3125836_21 regulation of single-species biofilm formation - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
HKD2_k127_3125836_22 FCD - - - 0.000000000000000000000000000000000000000000000000000004849 202.0
HKD2_k127_3125836_23 N-acetylglucosamine kinase activity K00884 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006040,GO:0006044,GO:0006082,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0045127,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901071,GO:1901135,GO:1901265,GO:1901363 2.7.1.59 0.0000000000000000000000000000000000000000000000000006385 195.0
HKD2_k127_3125836_24 beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000002168 197.0
HKD2_k127_3125836_25 Exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000002501 161.0
HKD2_k127_3125836_26 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000003465 161.0
HKD2_k127_3125836_27 acetyltransferase K22441 - 2.3.1.57 0.0000000000000000000000000000000000005866 146.0
HKD2_k127_3125836_28 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) K13201,K18747 GO:0000003,GO:0000280,GO:0000375,GO:0000377,GO:0000380,GO:0000381,GO:0000398,GO:0000900,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0003730,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006259,GO:0006310,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006996,GO:0007049,GO:0007127,GO:0007131,GO:0007154,GO:0007165,GO:0007166,GO:0007224,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007444,GO:0007446,GO:0007530,GO:0007538,GO:0007539,GO:0007541,GO:0007542,GO:0007548,GO:0007549,GO:0008150,GO:0008152,GO:0008187,GO:0008266,GO:0008380,GO:0009605,GO:0009607,GO:0009617,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009994,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0017148,GO:0018992,GO:0018993,GO:0019099,GO:0019101,GO:0019219,GO:0019222,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0023052,GO:0030154,GO:0030237,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033119,GO:0034248,GO:0034249,GO:0034641,GO:0035265,GO:0035295,GO:0035825,GO:0036002,GO:0040007,GO:0040029,GO:0042742,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043484,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044703,GO:0045182,GO:0045934,GO:0046483,GO:0048024,GO:0048025,GO:0048027,GO:0048285,GO:0048468,GO:0048477,GO:0048513,GO:0048519,GO:0048523,GO:0048589,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050684,GO:0050686,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051321,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060429,GO:0061982,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090079,GO:0090304,GO:0097159,GO:0098542,GO:0140013,GO:1901360,GO:1901363,GO:1903046,GO:1903311,GO:1903312,GO:2000112,GO:2000113 - 0.000000000051 70.0
HKD2_k127_3125836_29 Belongs to the universal stress protein A family - - - 0.00000002 62.0
HKD2_k127_3125836_3 Aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 4.052e-223 703.0
HKD2_k127_3125836_4 PFAM Uncharacterised BCR, COG1649 - - - 5.693e-214 682.0
HKD2_k127_3125836_5 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 559.0
HKD2_k127_3125836_6 Glycosyltransferase, group 2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 559.0
HKD2_k127_3125836_7 Proline racemase K12658 - 5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 538.0
HKD2_k127_3125836_8 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 510.0
HKD2_k127_3125836_9 Mandelate racemase muconate lactonizing enzyme K01776,K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20,5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 497.0
HKD2_k127_3202026_0 DNA-directed DNA polymerase activity K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1191.0
HKD2_k127_3202026_1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term K17108 - 3.2.1.45 1.705e-307 978.0
HKD2_k127_3202026_10 Bacterial protein of unknown function (DUF853) - - - 1.428e-220 694.0
HKD2_k127_3202026_11 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 8.707e-220 693.0
HKD2_k127_3202026_12 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 1.325e-209 672.0
HKD2_k127_3202026_13 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 590.0
HKD2_k127_3202026_14 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 582.0
HKD2_k127_3202026_15 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 597.0
HKD2_k127_3202026_16 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 563.0
HKD2_k127_3202026_17 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 550.0
HKD2_k127_3202026_18 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 540.0
HKD2_k127_3202026_19 transferase activity, transferring glycosyl groups K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 518.0
HKD2_k127_3202026_2 methionyl-tRNA aminoacylation K01874,K01890,K06878 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10,6.1.1.20 6.901e-287 896.0
HKD2_k127_3202026_20 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
HKD2_k127_3202026_21 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 505.0
HKD2_k127_3202026_22 radical SAM domain protein K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 482.0
HKD2_k127_3202026_23 Peptidase, M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 457.0
HKD2_k127_3202026_24 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 442.0
HKD2_k127_3202026_25 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 426.0
HKD2_k127_3202026_26 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 386.0
HKD2_k127_3202026_27 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 400.0
HKD2_k127_3202026_28 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 322.0
HKD2_k127_3202026_29 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 307.0
HKD2_k127_3202026_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.149e-268 848.0
HKD2_k127_3202026_30 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 321.0
HKD2_k127_3202026_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001638 290.0
HKD2_k127_3202026_32 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 270.0
HKD2_k127_3202026_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002264 274.0
HKD2_k127_3202026_34 Phage integrase, N-terminal SAM-like domain K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009444 267.0
HKD2_k127_3202026_35 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001506 273.0
HKD2_k127_3202026_36 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003681 257.0
HKD2_k127_3202026_37 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005717 253.0
HKD2_k127_3202026_38 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000002467 239.0
HKD2_k127_3202026_39 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000007557 250.0
HKD2_k127_3202026_4 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 4.267e-256 806.0
HKD2_k127_3202026_40 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000001819 232.0
HKD2_k127_3202026_41 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000005061 227.0
HKD2_k127_3202026_42 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000003195 218.0
HKD2_k127_3202026_43 heme binding K21471 - - 0.000000000000000000000000000000000000000000000000000000006516 210.0
HKD2_k127_3202026_44 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000138 205.0
HKD2_k127_3202026_45 membrane organization K07277 - - 0.0000000000000000000000000000000000000000000000000000006843 217.0
HKD2_k127_3202026_46 Domain of unknown function (DUF4835) - - - 0.0000000000000000000000000000000000000000000000000000008897 204.0
HKD2_k127_3202026_47 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000006333 194.0
HKD2_k127_3202026_48 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000002748 191.0
HKD2_k127_3202026_49 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000001572 184.0
HKD2_k127_3202026_5 Phosphoesterase family - - - 8.209e-256 812.0
HKD2_k127_3202026_50 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000008821 185.0
HKD2_k127_3202026_51 cell redox homeostasis - - - 0.00000000000000000000000000000000000000000000001037 179.0
HKD2_k127_3202026_52 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000342 172.0
HKD2_k127_3202026_53 belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000006775 166.0
HKD2_k127_3202026_54 Thioesterase-like superfamily K01075 - 3.1.2.23 0.0000000000000000000000000000000000000000001905 162.0
HKD2_k127_3202026_55 Metallophosphoesterase, calcineurin superfamily - - - 0.0000000000000000000000000000000000000000199 160.0
HKD2_k127_3202026_56 Domain of unknown function (DUF1949) - - - 0.000000000000000000000000000000000000001811 154.0
HKD2_k127_3202026_57 membrane - - - 0.000000000000000000000000000000000000002734 154.0
HKD2_k127_3202026_58 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000202 149.0
HKD2_k127_3202026_59 - - - - 0.0000000000000000000000000000000000001085 148.0
HKD2_k127_3202026_6 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.152e-238 754.0
HKD2_k127_3202026_60 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000001108 151.0
HKD2_k127_3202026_61 Signal peptidase (SPase) II K03101 - 3.4.23.36 0.000000000000000000000000000000001334 136.0
HKD2_k127_3202026_62 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000002558 129.0
HKD2_k127_3202026_64 Haem-binding domain - - - 0.0000000000000000000000000000001091 130.0
HKD2_k127_3202026_65 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000003891 137.0
HKD2_k127_3202026_66 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000001422 123.0
HKD2_k127_3202026_67 Winged helix DNA-binding domain - - - 0.00000000000000000000000006047 118.0
HKD2_k127_3202026_68 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA - - - 0.000000000000000000000006983 107.0
HKD2_k127_3202026_69 Helix-hairpin-helix motif - - - 0.0000000000000000000002893 113.0
HKD2_k127_3202026_7 glutamine synthetase K01915 - 6.3.1.2 1.199e-238 744.0
HKD2_k127_3202026_70 photosystem II stabilization - - - 0.00000000000000000007516 100.0
HKD2_k127_3202026_71 Belongs to the Smg family K03747 - - 0.0000000000000000002179 93.0
HKD2_k127_3202026_73 regulation of translation K03733,K05808,K05809 - - 0.0000000000000001594 84.0
HKD2_k127_3202026_74 - K01992 - - 0.000000000004183 77.0
HKD2_k127_3202026_75 Outer membrane protein beta-barrel domain K07275 - - 0.000000000005462 75.0
HKD2_k127_3202026_76 Predicted membrane protein (DUF2339) - - - 0.000000002403 70.0
HKD2_k127_3202026_77 - - - - 0.00000002841 64.0
HKD2_k127_3202026_78 - - - - 0.000001079 55.0
HKD2_k127_3202026_79 AraC-like ligand binding domain - - - 0.000005885 53.0
HKD2_k127_3202026_8 Domain of unknown function (DUF1846) - - - 1.316e-236 741.0
HKD2_k127_3202026_80 AntiSigma factor - - - 0.0005068 49.0
HKD2_k127_3202026_9 prolyl-tRNA aminoacylation K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 1.131e-234 738.0
HKD2_k127_3202661_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 511.0
HKD2_k127_3202661_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000002042 217.0
HKD2_k127_3994907_0 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000324 282.0
HKD2_k127_3994907_1 Cellulase (glycosyl hydrolase family 5) - - - 0.0000000000000000001474 103.0
HKD2_k127_4048497_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1390.0
HKD2_k127_4048497_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1370.0
HKD2_k127_4048497_10 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 1.004e-211 681.0
HKD2_k127_4048497_11 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 2.151e-203 646.0
HKD2_k127_4048497_12 amino acid K03294 - - 8.434e-203 646.0
HKD2_k127_4048497_13 Major Facilitator Superfamily - - - 5.089e-199 629.0
HKD2_k127_4048497_14 succinyl-diaminopimelate desuccinylase activity K01436,K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 578.0
HKD2_k127_4048497_15 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 574.0
HKD2_k127_4048497_16 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 567.0
HKD2_k127_4048497_17 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 544.0
HKD2_k127_4048497_18 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 539.0
HKD2_k127_4048497_19 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 521.0
HKD2_k127_4048497_2 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.0 1039.0
HKD2_k127_4048497_20 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 514.0
HKD2_k127_4048497_21 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 505.0
HKD2_k127_4048497_22 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 467.0
HKD2_k127_4048497_23 phosphate ion binding K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 454.0
HKD2_k127_4048497_24 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 433.0
HKD2_k127_4048497_25 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 430.0
HKD2_k127_4048497_26 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 415.0
HKD2_k127_4048497_27 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 395.0
HKD2_k127_4048497_28 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 398.0
HKD2_k127_4048497_29 inorganic phosphate transmembrane transporter activity K02037,K02038 GO:0008150,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044403,GO:0044419,GO:0051704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 381.0
HKD2_k127_4048497_3 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 8.607e-302 942.0
HKD2_k127_4048497_30 PFAM OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 391.0
HKD2_k127_4048497_31 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 379.0
HKD2_k127_4048497_32 ATPase-coupled phosphate ion transmembrane transporter activity K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 369.0
HKD2_k127_4048497_33 Cobyrinic acid ac-diamide synthase K03496 GO:0008150,GO:0022603,GO:0042173,GO:0042174,GO:0043937,GO:0043939,GO:0045595,GO:0045596,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051093,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 350.0
HKD2_k127_4048497_34 membrane organization K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 366.0
HKD2_k127_4048497_35 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 344.0
HKD2_k127_4048497_36 beta-galactosidase activity K01190 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 351.0
HKD2_k127_4048497_37 Pkd domain containing protein K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 356.0
HKD2_k127_4048497_38 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 323.0
HKD2_k127_4048497_39 proline dehydrogenase activity K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 314.0
HKD2_k127_4048497_4 nodulation K00612 - - 3.763e-297 921.0
HKD2_k127_4048497_40 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 306.0
HKD2_k127_4048497_41 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 296.0
HKD2_k127_4048497_42 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 292.0
HKD2_k127_4048497_43 translation initiation factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001619 284.0
HKD2_k127_4048497_44 2',3'-cyclic-nucleotide 2'-phosphodiesterase activity K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002158 280.0
HKD2_k127_4048497_45 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006475 285.0
HKD2_k127_4048497_46 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004183 280.0
HKD2_k127_4048497_47 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000375 270.0
HKD2_k127_4048497_48 Nucleoside recognition K06373,K06374 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 271.0
HKD2_k127_4048497_49 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004808 290.0
HKD2_k127_4048497_5 nucleotide-excision repair K03702,K08999 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 2.301e-283 892.0
HKD2_k127_4048497_50 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 258.0
HKD2_k127_4048497_51 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002744 243.0
HKD2_k127_4048497_52 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001001 247.0
HKD2_k127_4048497_53 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002226 242.0
HKD2_k127_4048497_54 Nucleoside recognition K06373,K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000000003614 235.0
HKD2_k127_4048497_56 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000725 230.0
HKD2_k127_4048497_57 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001291 222.0
HKD2_k127_4048497_58 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000007909 220.0
HKD2_k127_4048497_59 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001376 209.0
HKD2_k127_4048497_6 nuclear chromosome segregation K03529,K19171 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 5.863e-249 811.0
HKD2_k127_4048497_60 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000008604 213.0
HKD2_k127_4048497_61 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000003485 200.0
HKD2_k127_4048497_62 L-methionine salvage from methylthioadenosine K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000061 207.0
HKD2_k127_4048497_63 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000000000000002969 198.0
HKD2_k127_4048497_64 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000002704 184.0
HKD2_k127_4048497_65 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000001805 199.0
HKD2_k127_4048497_66 Endoribonuclease L-PSP K09021,K09022 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.99.10 0.000000000000000000000000000000000000000000008855 165.0
HKD2_k127_4048497_67 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000000002175 161.0
HKD2_k127_4048497_68 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000001093 159.0
HKD2_k127_4048497_69 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000001024 153.0
HKD2_k127_4048497_7 Glycosyl-hydrolase 97 C-terminal, oligomerisation K01187 - 3.2.1.20 4.615e-247 779.0
HKD2_k127_4048497_70 transcription factor binding - - - 0.0000000000000000000000000000000002153 134.0
HKD2_k127_4048497_71 ComF family K00764 - 2.4.2.14 0.000000000000000000000000000000003124 141.0
HKD2_k127_4048497_72 - - - - 0.000000000000000000000000007881 117.0
HKD2_k127_4048497_73 nucleic acid phosphodiester bond hydrolysis K07460 - - 0.00000000000000000000002415 105.0
HKD2_k127_4048497_74 protein secretion K15125 - - 0.000000000000000000000102 117.0
HKD2_k127_4048497_75 Histidine kinase - - - 0.000000000000000003918 88.0
HKD2_k127_4048497_76 - - - - 0.0000000000000001911 79.0
HKD2_k127_4048497_77 - - - - 0.000000000000000472 83.0
HKD2_k127_4048497_78 Lamin Tail Domain - - - 0.00000000000001354 87.0
HKD2_k127_4048497_79 Matrixin - - - 0.0000000004488 75.0
HKD2_k127_4048497_8 5TM C-terminal transporter carbon starvation CstA K06200 - - 4.357e-223 707.0
HKD2_k127_4048497_80 protein import K01179 - 3.2.1.4 0.0004705 50.0
HKD2_k127_4048497_9 Amino acid permease - - - 6.458e-212 676.0
HKD2_k127_4071242_0 peptidase S9 prolyl oligopeptidase active site domain protein - - - 1.099e-278 889.0
HKD2_k127_4071242_1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 4.228e-278 880.0
HKD2_k127_4071242_10 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 377.0
HKD2_k127_4071242_11 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 369.0
HKD2_k127_4071242_12 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 362.0
HKD2_k127_4071242_13 Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 359.0
HKD2_k127_4071242_14 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 347.0
HKD2_k127_4071242_15 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 336.0
HKD2_k127_4071242_16 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005397 261.0
HKD2_k127_4071242_17 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000003709 255.0
HKD2_k127_4071242_18 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000002692 250.0
HKD2_k127_4071242_19 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000094 241.0
HKD2_k127_4071242_2 cell wall glycoprotein biosynthetic process K01809 - 5.3.1.8 5.503e-246 773.0
HKD2_k127_4071242_20 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000003222 220.0
HKD2_k127_4071242_21 oxalate decarboxylase activity K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000008968 206.0
HKD2_k127_4071242_22 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000000000000000000000000000000838 221.0
HKD2_k127_4071242_23 Cupin 2, conserved barrel domain protein K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000004247 185.0
HKD2_k127_4071242_24 - - - - 0.000000000000000000000000000000000000000000000001205 184.0
HKD2_k127_4071242_25 glucan 1,4-alpha-glucosidase activity - - - 0.000000000000000000000000000000000000000000004753 188.0
HKD2_k127_4071242_26 - - - - 0.00000000000000000004652 96.0
HKD2_k127_4071242_27 - - - - 0.00000000002995 70.0
HKD2_k127_4071242_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 8.355e-195 613.0
HKD2_k127_4071242_4 PFAM N-acylglucosamine 2-epimerase K01787 - 5.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 560.0
HKD2_k127_4071242_5 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 560.0
HKD2_k127_4071242_6 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 542.0
HKD2_k127_4071242_7 Glycosyl hydrolase family 47 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 512.0
HKD2_k127_4071242_8 Sugar (and other) transporter K08138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 509.0
HKD2_k127_4071242_9 PFAM Peptidase family M1 K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 452.0
HKD2_k127_4264142_0 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 556.0
HKD2_k127_4264142_1 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 544.0
HKD2_k127_4264142_2 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 537.0
HKD2_k127_4264142_3 - - - - 0.0006046 44.0
HKD2_k127_4382652_0 CobQ CobB MinD ParA nucleotide binding domain K16554,K16692 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 615.0
HKD2_k127_4382652_1 Putative zinc binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 578.0
HKD2_k127_4382652_10 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 362.0
HKD2_k127_4382652_11 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 351.0
HKD2_k127_4382652_12 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 336.0
HKD2_k127_4382652_13 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002988 313.0
HKD2_k127_4382652_14 Epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000003306 246.0
HKD2_k127_4382652_15 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002864 233.0
HKD2_k127_4382652_16 TIGRFAM FemAB-related protein, PEP-CTERM system-associated - - - 0.00000000000000000000000000000000000000000000000000000000000676 221.0
HKD2_k127_4382652_17 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000003298 219.0
HKD2_k127_4382652_18 Endonuclease I - - - 0.0000000000000000000000000000000000000003195 175.0
HKD2_k127_4382652_19 Glycosyl transferases group 1 - - - 0.00000000000000000000000003239 122.0
HKD2_k127_4382652_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 558.0
HKD2_k127_4382652_20 Transcriptional regulator - - - 0.000000000000000000008461 99.0
HKD2_k127_4382652_21 polysaccharide export K01991 - - 0.00000000000000003837 90.0
HKD2_k127_4382652_22 cellulase activity - - - 0.000000002959 73.0
HKD2_k127_4382652_23 Fibronectin type 3 domain K01179,K01361,K01637,K01729,K09942,K20276 - 3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3 0.000000003728 63.0
HKD2_k127_4382652_24 - - - - 0.00001872 47.0
HKD2_k127_4382652_25 Sulfatase-modifying factor enzyme 1 - - - 0.0006156 49.0
HKD2_k127_4382652_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 529.0
HKD2_k127_4382652_4 UDP binding domain K00066 - 1.1.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 495.0
HKD2_k127_4382652_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
HKD2_k127_4382652_6 COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 439.0
HKD2_k127_4382652_7 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 405.0
HKD2_k127_4382652_8 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 394.0
HKD2_k127_4382652_9 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 386.0
HKD2_k127_4528843_0 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0 2129.0
HKD2_k127_4528843_1 Amino acid adenylation domain - - - 0.0 1313.0
HKD2_k127_4528843_2 D-alanine [D-alanyl carrier protein] ligase activity - - - 4.297e-316 1005.0
HKD2_k127_4528843_3 Ketoacyl-synthetase C-terminal extension - - - 1.04e-264 846.0
HKD2_k127_5060680_0 peptidase S9 prolyl oligopeptidase active site K01278 - 3.4.14.5 2.806e-283 885.0
HKD2_k127_5060680_1 Domain of unknown function (DUF5117) - - - 1.425e-203 665.0
HKD2_k127_5060680_10 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000001524 152.0
HKD2_k127_5060680_11 ApaG domain K06195 - - 0.000000000000000000000000000000000000004183 151.0
HKD2_k127_5060680_12 Phosphopantetheine attachment site - - - 0.000000000000000126 82.0
HKD2_k127_5060680_2 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 477.0
HKD2_k127_5060680_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 429.0
HKD2_k127_5060680_4 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 419.0
HKD2_k127_5060680_5 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 378.0
HKD2_k127_5060680_6 long-chain fatty acid transporting porin activity K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001821 269.0
HKD2_k127_5060680_7 Cys-tRNA(Pro) hydrolase activity K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000003405 203.0
HKD2_k127_5060680_8 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000009073 194.0
HKD2_k127_5060680_9 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000008014 151.0
HKD2_k127_5160451_0 alpha-L-rhamnosidase - - - 0.0 1177.0
HKD2_k127_5160451_1 4 iron, 4 sulfur cluster binding K00184 - - 0.0 1140.0
HKD2_k127_5160451_10 Domain of unknown function (DUF5110) K01811 - 3.2.1.177 8.121e-293 915.0
HKD2_k127_5160451_100 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000008424 262.0
HKD2_k127_5160451_101 thymidine kinase activity K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000007471 258.0
HKD2_k127_5160451_102 cobalamin-transporting ATPase activity K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001801 276.0
HKD2_k127_5160451_103 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003925 259.0
HKD2_k127_5160451_104 Anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000006018 258.0
HKD2_k127_5160451_105 cellulose binding K00505 - 1.14.18.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002951 273.0
HKD2_k127_5160451_106 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004168 261.0
HKD2_k127_5160451_107 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000009739 254.0
HKD2_k127_5160451_108 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000002507 254.0
HKD2_k127_5160451_109 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02841,K02843,K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002849 251.0
HKD2_k127_5160451_11 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.591e-292 922.0
HKD2_k127_5160451_110 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007605 247.0
HKD2_k127_5160451_111 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001147 258.0
HKD2_k127_5160451_112 purine ribonucleoside salvage K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000001598 237.0
HKD2_k127_5160451_113 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000001571 235.0
HKD2_k127_5160451_114 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000005843 231.0
HKD2_k127_5160451_115 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002252 239.0
HKD2_k127_5160451_116 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000001082 232.0
HKD2_k127_5160451_117 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000001966 237.0
HKD2_k127_5160451_118 Cytochrome c K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000002733 231.0
HKD2_k127_5160451_119 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000003356 233.0
HKD2_k127_5160451_12 hydrolase, family 65, central catalytic - - - 1.85e-279 878.0
HKD2_k127_5160451_120 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000003522 235.0
HKD2_k127_5160451_121 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000003214 228.0
HKD2_k127_5160451_122 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000001395 211.0
HKD2_k127_5160451_123 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000004347 220.0
HKD2_k127_5160451_124 Cytochrome c, class I K08738 - - 0.00000000000000000000000000000000000000000000000000000000008636 223.0
HKD2_k127_5160451_125 spore germination - - - 0.0000000000000000000000000000000000000000000000000000000001778 214.0
HKD2_k127_5160451_126 PFAM diacylglycerol kinase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000007022 213.0
HKD2_k127_5160451_127 glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004158 211.0
HKD2_k127_5160451_128 translation initiation factor activity K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.0000000000000000000000000000000000000000000000000000005778 198.0
HKD2_k127_5160451_129 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000314 200.0
HKD2_k127_5160451_13 Fibronectin type III-like domain K05349 - 3.2.1.21 8.199e-269 858.0
HKD2_k127_5160451_130 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus K03624 - - 0.00000000000000000000000000000000000000000000000000003735 192.0
HKD2_k127_5160451_131 FtsZ-dependent cytokinesis - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001613 186.0
HKD2_k127_5160451_132 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000001927 196.0
HKD2_k127_5160451_133 Ferritin, Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000003814 182.0
HKD2_k127_5160451_134 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000004613 184.0
HKD2_k127_5160451_135 sequence-specific DNA binding K03719 - - 0.0000000000000000000000000000000000000000000000001215 181.0
HKD2_k127_5160451_136 L-rhamnose mutarotase K03534 - 5.1.3.32 0.0000000000000000000000000000000000000000000000003529 177.0
HKD2_k127_5160451_137 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000001842 183.0
HKD2_k127_5160451_138 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000515 192.0
HKD2_k127_5160451_139 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000004732 173.0
HKD2_k127_5160451_14 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.049e-268 842.0
HKD2_k127_5160451_140 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000006187 166.0
HKD2_k127_5160451_141 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000002181 177.0
HKD2_k127_5160451_142 nucleotidyltransferase activity - - - 0.00000000000000000000000000000000000000000009429 173.0
HKD2_k127_5160451_143 Protein of unknown function (DUF1761) - - - 0.000000000000000000000000000000000000000000341 162.0
HKD2_k127_5160451_144 Aminomethyltransferase folate-binding domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000001373 170.0
HKD2_k127_5160451_145 PFAM Glycoside hydrolase, family 20, catalytic core K12373 - 3.2.1.52 0.000000000000000000000000000000000000000001905 178.0
HKD2_k127_5160451_146 carbon-nitrogen ligase activity, with glutamine as amido-N-donor K09117 - - 0.000000000000000000000000000000000000000006588 160.0
HKD2_k127_5160451_147 Belongs to the binding-protein-dependent transport system permease family K02057,K10440,K17214 - - 0.00000000000000000000000000000000000000003118 165.0
HKD2_k127_5160451_148 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000004546 159.0
HKD2_k127_5160451_149 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000009141 154.0
HKD2_k127_5160451_15 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.606e-261 824.0
HKD2_k127_5160451_150 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.0000000000000000000000000000000000000001927 164.0
HKD2_k127_5160451_151 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000006417 160.0
HKD2_k127_5160451_152 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000008456 151.0
HKD2_k127_5160451_153 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000001006 147.0
HKD2_k127_5160451_154 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.00000000000000000000000000000000001504 143.0
HKD2_k127_5160451_155 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000000000000000000000004756 148.0
HKD2_k127_5160451_156 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000004779 138.0
HKD2_k127_5160451_157 rRNA binding K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000002537 130.0
HKD2_k127_5160451_158 ATP synthesis coupled electron transport K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000002786 130.0
HKD2_k127_5160451_159 PTS system, Lactose/Cellobiose specific IIB subunit K02769 - 2.7.1.202 0.000000000000000000000000000003079 122.0
HKD2_k127_5160451_16 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 3.563e-260 811.0
HKD2_k127_5160451_160 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000002991 123.0
HKD2_k127_5160451_161 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000008652 126.0
HKD2_k127_5160451_162 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000002549 119.0
HKD2_k127_5160451_163 Flavin reductase like domain - - - 0.0000000000000000000000000002927 120.0
HKD2_k127_5160451_164 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000006743 126.0
HKD2_k127_5160451_165 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.0000000000000000000000000009263 130.0
HKD2_k127_5160451_168 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000006052 121.0
HKD2_k127_5160451_169 Belongs to the 5'-nucleotidase family - - - 0.00000000000000000000000007719 120.0
HKD2_k127_5160451_17 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.172e-258 812.0
HKD2_k127_5160451_170 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000008332 115.0
HKD2_k127_5160451_171 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.000000000000000000000001101 108.0
HKD2_k127_5160451_172 nucleotide catabolic process - - - 0.000000000000000000000001739 120.0
HKD2_k127_5160451_173 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 0.000000000000000000000003636 120.0
HKD2_k127_5160451_174 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000006566 107.0
HKD2_k127_5160451_175 Protein of unknown function (DUF971) - - - 0.00000000000000000000003736 102.0
HKD2_k127_5160451_177 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000006226 105.0
HKD2_k127_5160451_178 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000001678 96.0
HKD2_k127_5160451_179 Polymer-forming cytoskeletal - - - 0.000000000000000000002654 107.0
HKD2_k127_5160451_18 Sulfatase-modifying factor enzyme 1 - - - 3.532e-258 827.0
HKD2_k127_5160451_180 Helix-hairpin-helix motif - - - 0.000000000000000000003294 98.0
HKD2_k127_5160451_181 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000008751 99.0
HKD2_k127_5160451_182 metallopeptidase activity K01179,K01181 - 3.2.1.4,3.2.1.8 0.0000000000000000004102 100.0
HKD2_k127_5160451_183 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000000001483 88.0
HKD2_k127_5160451_184 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000002198 85.0
HKD2_k127_5160451_185 Belongs to the peptidase S8 family - - - 0.000000000000000029 96.0
HKD2_k127_5160451_187 - - - - 0.0000000000001588 76.0
HKD2_k127_5160451_19 Glycosyl hydrolases family 38 N-terminal domain - - - 5.65e-258 834.0
HKD2_k127_5160451_191 Hemerythrin HHE cation binding domain K09155 - - 0.0000004888 58.0
HKD2_k127_5160451_194 - - - - 0.0001024 46.0
HKD2_k127_5160451_195 Colicin V production protein K03558 - - 0.0001459 51.0
HKD2_k127_5160451_196 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0003627 47.0
HKD2_k127_5160451_2 TonB-dependent receptor - - - 0.0 1083.0
HKD2_k127_5160451_20 heme-copper terminal oxidase activity K02274 - 1.9.3.1 3.444e-256 799.0
HKD2_k127_5160451_21 glutamine synthetase K01915 - 6.3.1.2 8.01e-256 798.0
HKD2_k127_5160451_22 Polysulphide reductase, NrfD K00185 - - 1.981e-234 732.0
HKD2_k127_5160451_23 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 2.295e-232 745.0
HKD2_k127_5160451_24 serine-type peptidase activity K06889,K07214 - - 6.375e-228 734.0
HKD2_k127_5160451_25 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.684e-228 722.0
HKD2_k127_5160451_26 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 1.221e-227 736.0
HKD2_k127_5160451_27 tryptophanase activity K01667 - 4.1.99.1 3.379e-224 702.0
HKD2_k127_5160451_28 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 9.99e-215 674.0
HKD2_k127_5160451_29 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 5.869e-213 674.0
HKD2_k127_5160451_3 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 0.0 1069.0
HKD2_k127_5160451_30 mRNA catabolic process K18682 - - 1.11e-210 666.0
HKD2_k127_5160451_31 PEP-utilising enzyme, N-terminal K08483,K11189,K11201 - 2.7.3.9 6.522e-209 677.0
HKD2_k127_5160451_32 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 1.098e-202 647.0
HKD2_k127_5160451_33 PFAM NAD-dependent epimerase dehydratase - - - 3.557e-197 626.0
HKD2_k127_5160451_34 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 612.0
HKD2_k127_5160451_35 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 626.0
HKD2_k127_5160451_36 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 595.0
HKD2_k127_5160451_37 carboxylase, biotin carboxylase K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 576.0
HKD2_k127_5160451_38 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 576.0
HKD2_k127_5160451_39 C-terminal region of aryl-sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 585.0
HKD2_k127_5160451_4 Amylo-alpha-1,6-glucosidase - - - 0.0 1068.0
HKD2_k127_5160451_40 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 563.0
HKD2_k127_5160451_41 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 564.0
HKD2_k127_5160451_42 amino acid activation for nonribosomal peptide biosynthetic process K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 583.0
HKD2_k127_5160451_43 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 552.0
HKD2_k127_5160451_44 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 559.0
HKD2_k127_5160451_45 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 551.0
HKD2_k127_5160451_46 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 539.0
HKD2_k127_5160451_47 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K00558,K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 2.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 539.0
HKD2_k127_5160451_48 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 527.0
HKD2_k127_5160451_5 Glycosyl hydrolases family 38 C-terminal domain - - - 0.0 1061.0
HKD2_k127_5160451_50 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 513.0
HKD2_k127_5160451_51 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 488.0
HKD2_k127_5160451_52 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 508.0
HKD2_k127_5160451_53 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 482.0
HKD2_k127_5160451_54 Stage II sporulation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 475.0
HKD2_k127_5160451_55 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 477.0
HKD2_k127_5160451_56 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 466.0
HKD2_k127_5160451_57 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 466.0
HKD2_k127_5160451_58 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 463.0
HKD2_k127_5160451_59 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 462.0
HKD2_k127_5160451_6 Trehalase K03931 - - 0.0 1043.0
HKD2_k127_5160451_60 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 462.0
HKD2_k127_5160451_61 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 471.0
HKD2_k127_5160451_62 PTS system, fructose subfamily, IIC subunit K02768,K02769,K02770,K11203 - 2.7.1.202 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 451.0
HKD2_k127_5160451_63 zinc ion transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 443.0
HKD2_k127_5160451_64 phospho-2-dehydro-3-deoxyheptonate aldolase K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 438.0
HKD2_k127_5160451_65 Glycogen debranching enzyme K18206 - 3.2.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 458.0
HKD2_k127_5160451_66 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 442.0
HKD2_k127_5160451_67 phenylalanine-tRNA ligase activity K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 434.0
HKD2_k127_5160451_68 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 429.0
HKD2_k127_5160451_69 Carbohydrate esterase, sialic acid-specific acetylesterase K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 439.0
HKD2_k127_5160451_7 COG NOG04001 non supervised orthologous group K15923 - 3.2.1.51 0.0 1040.0
HKD2_k127_5160451_70 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 429.0
HKD2_k127_5160451_71 arsenite transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 425.0
HKD2_k127_5160451_72 Alpha mannosidase, middle domain K01191 - 3.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 428.0
HKD2_k127_5160451_73 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 413.0
HKD2_k127_5160451_74 Trehalase K03931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 415.0
HKD2_k127_5160451_75 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 391.0
HKD2_k127_5160451_76 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 396.0
HKD2_k127_5160451_77 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 392.0
HKD2_k127_5160451_78 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 387.0
HKD2_k127_5160451_79 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 371.0
HKD2_k127_5160451_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.476e-315 981.0
HKD2_k127_5160451_80 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 367.0
HKD2_k127_5160451_81 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 359.0
HKD2_k127_5160451_82 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 354.0
HKD2_k127_5160451_83 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 344.0
HKD2_k127_5160451_84 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 337.0
HKD2_k127_5160451_85 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 340.0
HKD2_k127_5160451_86 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 330.0
HKD2_k127_5160451_87 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 326.0
HKD2_k127_5160451_88 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 317.0
HKD2_k127_5160451_89 Glyco_18 K01183 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005576,GO:0006022,GO:0006026,GO:0006030,GO:0006032,GO:0006040,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016798,GO:0017144,GO:0042737,GO:0043170,GO:0044237,GO:0044248,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 317.0
HKD2_k127_5160451_9 TonB-dependent receptor - - - 1.283e-311 984.0
HKD2_k127_5160451_90 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 307.0
HKD2_k127_5160451_91 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 297.0
HKD2_k127_5160451_92 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007275 293.0
HKD2_k127_5160451_93 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001822 284.0
HKD2_k127_5160451_94 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009705 291.0
HKD2_k127_5160451_95 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000027 272.0
HKD2_k127_5160451_96 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003311 271.0
HKD2_k127_5160451_97 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000002791 268.0
HKD2_k127_5160451_98 purine nucleotide biosynthetic process K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000894 273.0
HKD2_k127_5160451_99 Domain of unknown function (DUF5009) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009828 277.0
HKD2_k127_5170928_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1297.0
HKD2_k127_5170928_1 DNA topoisomerase II activity K02469 - 5.99.1.3 0.0 1177.0
HKD2_k127_5170928_10 DNA topoisomerase II activity K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 4.74e-282 881.0
HKD2_k127_5170928_100 Transferase K02527,K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33,2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 434.0
HKD2_k127_5170928_101 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 432.0
HKD2_k127_5170928_102 oxidative phosphorylation K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 419.0
HKD2_k127_5170928_103 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 422.0
HKD2_k127_5170928_104 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 421.0
HKD2_k127_5170928_105 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 418.0
HKD2_k127_5170928_106 fructose 1,6-bisphosphate 1-phosphatase activity K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
HKD2_k127_5170928_107 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 418.0
HKD2_k127_5170928_108 Chase2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 439.0
HKD2_k127_5170928_109 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 426.0
HKD2_k127_5170928_11 ABC transporter - - - 8.803e-273 847.0
HKD2_k127_5170928_110 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 408.0
HKD2_k127_5170928_111 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 425.0
HKD2_k127_5170928_112 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 407.0
HKD2_k127_5170928_113 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 399.0
HKD2_k127_5170928_114 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 402.0
HKD2_k127_5170928_115 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 415.0
HKD2_k127_5170928_116 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 397.0
HKD2_k127_5170928_117 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 389.0
HKD2_k127_5170928_118 purine-nucleoside phosphorylase activity K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 389.0
HKD2_k127_5170928_119 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 398.0
HKD2_k127_5170928_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016469,GO:0030312,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 3.6.3.14 1.267e-258 804.0
HKD2_k127_5170928_120 symporter activity K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 399.0
HKD2_k127_5170928_121 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 388.0
HKD2_k127_5170928_122 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 390.0
HKD2_k127_5170928_123 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006797,GO:0006798,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008894,GO:0009056,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034641,GO:0042594,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:1901360,GO:1901575 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 395.0
HKD2_k127_5170928_124 phosphate acetyltransferase K00029,K00625,K13788 - 1.1.1.40,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 385.0
HKD2_k127_5170928_125 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 400.0
HKD2_k127_5170928_126 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 389.0
HKD2_k127_5170928_127 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 383.0
HKD2_k127_5170928_128 metalloendopeptidase activity K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 386.0
HKD2_k127_5170928_129 Flavoprotein K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 385.0
HKD2_k127_5170928_13 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.103e-258 818.0
HKD2_k127_5170928_130 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 382.0
HKD2_k127_5170928_131 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 383.0
HKD2_k127_5170928_132 ATP-dependent DNA helicase activity K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 380.0
HKD2_k127_5170928_133 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 383.0
HKD2_k127_5170928_134 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 376.0
HKD2_k127_5170928_135 protein (some members contain a von Willebrand factor type A (vWA) domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 372.0
HKD2_k127_5170928_136 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 378.0
HKD2_k127_5170928_137 PFAM Glycosyl transferase family 2 K19003 - 2.4.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 374.0
HKD2_k127_5170928_138 peptidyl-prolyl cis-trans isomerase activity K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 376.0
HKD2_k127_5170928_139 HI0933 family K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 373.0
HKD2_k127_5170928_14 GTP-binding protein TypA K06207 - - 5.466e-253 793.0
HKD2_k127_5170928_140 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 373.0
HKD2_k127_5170928_141 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 367.0
HKD2_k127_5170928_142 Sigma-54 interaction domain K03413,K13589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 359.0
HKD2_k127_5170928_143 [acyl-carrier-protein] S-malonyltransferase activity K00645,K15327,K15329,K15355,K15469 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 354.0
HKD2_k127_5170928_144 Peptidase family M1 domain K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 366.0
HKD2_k127_5170928_145 Acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 357.0
HKD2_k127_5170928_146 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 366.0
HKD2_k127_5170928_147 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 347.0
HKD2_k127_5170928_148 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 355.0
HKD2_k127_5170928_149 Component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 355.0
HKD2_k127_5170928_15 (ABC) transporter K06147,K18890 - - 1.87e-247 779.0
HKD2_k127_5170928_150 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 346.0
HKD2_k127_5170928_151 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 349.0
HKD2_k127_5170928_152 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 339.0
HKD2_k127_5170928_153 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 348.0
HKD2_k127_5170928_154 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 333.0
HKD2_k127_5170928_155 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 337.0
HKD2_k127_5170928_156 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 344.0
HKD2_k127_5170928_157 fatty acid biosynthetic process K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 333.0
HKD2_k127_5170928_158 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 344.0
HKD2_k127_5170928_159 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 321.0
HKD2_k127_5170928_16 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 7.518e-242 768.0
HKD2_k127_5170928_160 peptidoglycan glycosyltransferase activity K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 332.0
HKD2_k127_5170928_161 oxidoreductase activity K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 331.0
HKD2_k127_5170928_162 FMN binding K01823 GO:0003674,GO:0003824,GO:0004452,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0071704,GO:1901576 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 327.0
HKD2_k127_5170928_163 NADH ubiquinone oxidoreductase K05588 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 319.0
HKD2_k127_5170928_164 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 324.0
HKD2_k127_5170928_165 metalloendopeptidase activity K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 324.0
HKD2_k127_5170928_166 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 321.0
HKD2_k127_5170928_167 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 323.0
HKD2_k127_5170928_168 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 319.0
HKD2_k127_5170928_169 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 335.0
HKD2_k127_5170928_17 CTP synthase activity K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016020,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 4.414e-240 756.0
HKD2_k127_5170928_170 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 313.0
HKD2_k127_5170928_171 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 312.0
HKD2_k127_5170928_172 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 330.0
HKD2_k127_5170928_173 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 304.0
HKD2_k127_5170928_174 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
HKD2_k127_5170928_175 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 310.0
HKD2_k127_5170928_176 proton-transporting ATP synthase activity, rotational mechanism K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 306.0
HKD2_k127_5170928_177 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 302.0
HKD2_k127_5170928_178 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 307.0
HKD2_k127_5170928_179 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 309.0
HKD2_k127_5170928_18 C-terminus of AA_permease K03294 - - 6.103e-238 745.0
HKD2_k127_5170928_180 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05827,K05844 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 303.0
HKD2_k127_5170928_181 Periplasmic binding proteins and sugar binding domain of LacI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 306.0
HKD2_k127_5170928_182 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 302.0
HKD2_k127_5170928_183 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 300.0
HKD2_k127_5170928_184 dUTP biosynthetic process K01494,K01520 - 3.5.4.13,3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 299.0
HKD2_k127_5170928_185 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 295.0
HKD2_k127_5170928_186 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 294.0
HKD2_k127_5170928_187 rRNA (adenine-C2-)-methyltransferase activity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 300.0
HKD2_k127_5170928_188 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 318.0
HKD2_k127_5170928_189 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 300.0
HKD2_k127_5170928_19 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 2.219e-232 743.0
HKD2_k127_5170928_190 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 296.0
HKD2_k127_5170928_191 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 296.0
HKD2_k127_5170928_192 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 287.0
HKD2_k127_5170928_193 peptidyl-prolyl cis-trans isomerase activity K03769,K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 308.0
HKD2_k127_5170928_194 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 286.0
HKD2_k127_5170928_195 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003162 280.0
HKD2_k127_5170928_196 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004977 282.0
HKD2_k127_5170928_197 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001082 285.0
HKD2_k127_5170928_198 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001282 286.0
HKD2_k127_5170928_199 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003269 304.0
HKD2_k127_5170928_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0 1144.0
HKD2_k127_5170928_20 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K05587 - 1.6.5.3 2.125e-223 706.0
HKD2_k127_5170928_200 Inward rectifier potassium channel K08715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001593 276.0
HKD2_k127_5170928_201 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000227 273.0
HKD2_k127_5170928_202 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004589 268.0
HKD2_k127_5170928_203 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008061 283.0
HKD2_k127_5170928_204 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001002 278.0
HKD2_k127_5170928_205 Sigma factor PP2C-like phosphatases K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001119 285.0
HKD2_k127_5170928_206 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 271.0
HKD2_k127_5170928_207 cyclic nucleotide binding K01420,K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009647 269.0
HKD2_k127_5170928_208 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
HKD2_k127_5170928_209 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002589 269.0
HKD2_k127_5170928_21 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K10754 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.425e-223 709.0
HKD2_k127_5170928_210 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005328 272.0
HKD2_k127_5170928_211 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 279.0
HKD2_k127_5170928_212 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002668 263.0
HKD2_k127_5170928_213 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000004381 267.0
HKD2_k127_5170928_214 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007643 269.0
HKD2_k127_5170928_215 - K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001103 263.0
HKD2_k127_5170928_216 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004702 263.0
HKD2_k127_5170928_217 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005229 259.0
HKD2_k127_5170928_218 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 259.0
HKD2_k127_5170928_219 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000007491 253.0
HKD2_k127_5170928_22 transferase activity, transferring glycosyl groups K00694,K00786 - 2.4.1.12 9.164e-222 696.0
HKD2_k127_5170928_220 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009059 245.0
HKD2_k127_5170928_221 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001916 243.0
HKD2_k127_5170928_222 Phosphate acetyl/butaryl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000086 250.0
HKD2_k127_5170928_223 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000002359 241.0
HKD2_k127_5170928_224 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000003185 246.0
HKD2_k127_5170928_225 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005765 263.0
HKD2_k127_5170928_226 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000117 267.0
HKD2_k127_5170928_227 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000000003648 243.0
HKD2_k127_5170928_228 Chaperone - - - 0.00000000000000000000000000000000000000000000000000000000000000000005119 243.0
HKD2_k127_5170928_229 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000009222 235.0
HKD2_k127_5170928_23 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 2.26e-218 696.0
HKD2_k127_5170928_230 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
HKD2_k127_5170928_231 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
HKD2_k127_5170928_232 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004475 244.0
HKD2_k127_5170928_233 PFAM YicC-like family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000001273 235.0
HKD2_k127_5170928_234 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000008941 233.0
HKD2_k127_5170928_235 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
HKD2_k127_5170928_236 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000001255 228.0
HKD2_k127_5170928_237 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000001336 228.0
HKD2_k127_5170928_238 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003025 225.0
HKD2_k127_5170928_239 Protein of unknown function (DUF2851) - - - 0.000000000000000000000000000000000000000000000000000000000000003724 235.0
HKD2_k127_5170928_24 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 3.18e-214 673.0
HKD2_k127_5170928_240 Glycosyl transferase, family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000000001967 230.0
HKD2_k127_5170928_241 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002691 221.0
HKD2_k127_5170928_242 - - - - 0.00000000000000000000000000000000000000000000000000000000000003224 223.0
HKD2_k127_5170928_243 PFAM Appr-1-p processing - - - 0.0000000000000000000000000000000000000000000000000000000000002131 217.0
HKD2_k127_5170928_244 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000005196 220.0
HKD2_k127_5170928_245 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000002041 218.0
HKD2_k127_5170928_246 membrane organization K07277 - - 0.000000000000000000000000000000000000000000000000000000000002699 227.0
HKD2_k127_5170928_247 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000001082 219.0
HKD2_k127_5170928_248 PFAM UvrB UvrC protein K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000001935 211.0
HKD2_k127_5170928_249 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000005995 210.0
HKD2_k127_5170928_25 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.041e-211 675.0
HKD2_k127_5170928_250 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000008118 233.0
HKD2_k127_5170928_251 pectinesterase activity K10297,K15923,K18197,K19615 - 3.2.1.51,4.2.2.23 0.0000000000000000000000000000000000000000000000000000000001183 227.0
HKD2_k127_5170928_252 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000005646 212.0
HKD2_k127_5170928_253 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000000000000000001891 216.0
HKD2_k127_5170928_254 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001482 202.0
HKD2_k127_5170928_255 Dihydrouridine synthase (Dus) K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000001628 206.0
HKD2_k127_5170928_256 - - - - 0.00000000000000000000000000000000000000000000000000000003817 208.0
HKD2_k127_5170928_257 DinB family - - - 0.00000000000000000000000000000000000000000000000000000003981 201.0
HKD2_k127_5170928_258 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000000000000000000000000000000000000000000000000000006378 211.0
HKD2_k127_5170928_259 Glycosyl transferase, family 9 K02841,K02843,K02847,K02849,K21003 - - 0.00000000000000000000000000000000000000000000000000000013 208.0
HKD2_k127_5170928_26 TonB-dependent receptor K02014 - - 1.286e-210 680.0
HKD2_k127_5170928_260 Essential for recycling GMP and indirectly, cGMP K00942,K01591 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8,4.1.1.23 0.000000000000000000000000000000000000000000000000000000175 200.0
HKD2_k127_5170928_261 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000008465 215.0
HKD2_k127_5170928_262 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000003232 199.0
HKD2_k127_5170928_263 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.00000000000000000000000000000000000000000000000000000505 194.0
HKD2_k127_5170928_264 ribonuclease III activity K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000006323 196.0
HKD2_k127_5170928_265 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000006339 190.0
HKD2_k127_5170928_266 PFAM Uncharacterised ACR, YkgG family COG1556 - - - 0.00000000000000000000000000000000000000000000000000009319 193.0
HKD2_k127_5170928_267 peptidase - - - 0.0000000000000000000000000000000000000000000000000001741 200.0
HKD2_k127_5170928_268 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000001963 210.0
HKD2_k127_5170928_269 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000462 191.0
HKD2_k127_5170928_27 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 3.244e-210 674.0
HKD2_k127_5170928_270 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000006843 190.0
HKD2_k127_5170928_271 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000009834 184.0
HKD2_k127_5170928_272 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000004962 173.0
HKD2_k127_5170928_273 COGs COG0680 Ni Fe-hydrogenase maturation factor K03605 - - 0.0000000000000000000000000000000000000000000001586 172.0
HKD2_k127_5170928_274 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000208 171.0
HKD2_k127_5170928_275 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000002315 182.0
HKD2_k127_5170928_276 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000000000000000000000000000006897 173.0
HKD2_k127_5170928_277 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000007213 180.0
HKD2_k127_5170928_278 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000008688 176.0
HKD2_k127_5170928_279 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000001456 176.0
HKD2_k127_5170928_28 phosphopyruvate hydratase activity K01689 GO:0001968,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005518,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035375,GO:0042866,GO:0043236,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0044877,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050840,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 4.2.1.11 7.566e-210 660.0
HKD2_k127_5170928_280 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004552 169.0
HKD2_k127_5170928_281 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000000000000000007231 171.0
HKD2_k127_5170928_282 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000003624 170.0
HKD2_k127_5170928_283 Thioesterase K07107 - - 0.0000000000000000000000000000000000000000001203 163.0
HKD2_k127_5170928_284 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000001396 168.0
HKD2_k127_5170928_285 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000004857 181.0
HKD2_k127_5170928_286 protein trimerization - - - 0.0000000000000000000000000000000000000000005009 172.0
HKD2_k127_5170928_287 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000008823 166.0
HKD2_k127_5170928_288 PAAR repeat-containing protein - - - 0.0000000000000000000000000000000000000000009051 177.0
HKD2_k127_5170928_29 Cytochrome c554 and c-prime - - - 1.258e-208 661.0
HKD2_k127_5170928_290 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000005366 158.0
HKD2_k127_5170928_291 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000001567 165.0
HKD2_k127_5170928_292 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000001736 162.0
HKD2_k127_5170928_293 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000000000007624 158.0
HKD2_k127_5170928_294 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000007752 164.0
HKD2_k127_5170928_295 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000002022 154.0
HKD2_k127_5170928_296 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K07081,K11782,K11784 - 1.21.98.1,4.2.1.151 0.0000000000000000000000000000000000000003893 161.0
HKD2_k127_5170928_297 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000005414 157.0
HKD2_k127_5170928_298 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000868 159.0
HKD2_k127_5170928_299 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000276 156.0
HKD2_k127_5170928_3 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1075.0
HKD2_k127_5170928_30 ABC transporter K06158 - - 1.335e-207 664.0
HKD2_k127_5170928_300 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 - - 0.0000000000000000000000000000000000000474 151.0
HKD2_k127_5170928_301 Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily K09457 - 1.7.1.13 0.00000000000000000000000000000000000008684 152.0
HKD2_k127_5170928_302 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000000000000000000000000000001114 154.0
HKD2_k127_5170928_303 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000001816 156.0
HKD2_k127_5170928_304 PFAM CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000002273 147.0
HKD2_k127_5170928_306 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000009384 145.0
HKD2_k127_5170928_307 Peptidase family M23 - - - 0.000000000000000000000000000000000002005 149.0
HKD2_k127_5170928_308 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000003804 146.0
HKD2_k127_5170928_309 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000004453 156.0
HKD2_k127_5170928_31 UDP-N-acetylmuramate-L-alanine ligase activity K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 5.167e-207 653.0
HKD2_k127_5170928_310 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000001096 141.0
HKD2_k127_5170928_311 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000001744 140.0
HKD2_k127_5170928_312 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000003091 151.0
HKD2_k127_5170928_313 ABC-type Mn2 Zn2 transport systems permease components K02075,K09816 - - 0.00000000000000000000000000000000004869 144.0
HKD2_k127_5170928_314 cellulose binding - - - 0.00000000000000000000000000000000007734 149.0
HKD2_k127_5170928_315 - - - - 0.0000000000000000000000000000000001193 144.0
HKD2_k127_5170928_316 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000003443 136.0
HKD2_k127_5170928_317 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.00000000000000000000000000000000119 136.0
HKD2_k127_5170928_318 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000001073 139.0
HKD2_k127_5170928_319 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000002434 130.0
HKD2_k127_5170928_32 Sigma-54 interaction domain K03405 - 6.6.1.1 1.118e-198 631.0
HKD2_k127_5170928_320 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000002552 128.0
HKD2_k127_5170928_321 serine-type aminopeptidase activity - - - 0.00000000000000000000000000000003061 136.0
HKD2_k127_5170928_322 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000004237 132.0
HKD2_k127_5170928_323 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000001682 134.0
HKD2_k127_5170928_324 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000005905 136.0
HKD2_k127_5170928_325 zinc ion binding K06204 - - 0.0000000000000000000000000000008935 129.0
HKD2_k127_5170928_326 THIamine pyrophosphokinase K00949 - 2.7.6.2 0.000000000000000000000000000004277 128.0
HKD2_k127_5170928_328 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000009202 119.0
HKD2_k127_5170928_329 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000003833 118.0
HKD2_k127_5170928_33 - - - - 1.683e-198 626.0
HKD2_k127_5170928_330 chaperone-mediated protein folding - - - 0.00000000000000000000000000005052 133.0
HKD2_k127_5170928_331 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.0000000000000000000000000001269 121.0
HKD2_k127_5170928_332 regulation of translation K03530 - - 0.0000000000000000000000000002147 116.0
HKD2_k127_5170928_333 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000002208 131.0
HKD2_k127_5170928_334 shape-determining protein MreC K03570 - - 0.0000000000000000000000000003845 124.0
HKD2_k127_5170928_335 DivIVA protein K04074,K07484 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000007258 121.0
HKD2_k127_5170928_336 PTS HPr component phosphorylation site K11189 - - 0.0000000000000000000000000008966 114.0
HKD2_k127_5170928_337 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.000000000000000000000000001131 123.0
HKD2_k127_5170928_338 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000261 117.0
HKD2_k127_5170928_339 COG0402 Cytosine deaminase and related metal-dependent hydrolases K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000003841 128.0
HKD2_k127_5170928_34 (ABC) transporter K06147,K18889 - - 1.697e-196 628.0
HKD2_k127_5170928_340 Cold shock protein domain K03704 - - 0.000000000000000000000000004803 112.0
HKD2_k127_5170928_341 membrane transporter protein K07090 - - 0.00000000000000000000000008616 117.0
HKD2_k127_5170928_342 Glycosyl transferases group 1 - - - 0.0000000000000000000000001225 116.0
HKD2_k127_5170928_343 Thioredoxin - - - 0.0000000000000000000000001891 114.0
HKD2_k127_5170928_344 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000362 122.0
HKD2_k127_5170928_345 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000007572 122.0
HKD2_k127_5170928_346 methylated DNA-protein cysteine methyltransferase K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 - 0.0000000000000000000000009242 112.0
HKD2_k127_5170928_347 Protein of unknown function (DUF3276) - - - 0.000000000000000000000001206 106.0
HKD2_k127_5170928_348 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000001536 109.0
HKD2_k127_5170928_349 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000002026 106.0
HKD2_k127_5170928_35 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 4.124e-196 633.0
HKD2_k127_5170928_350 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 0.000000000000000000000003059 117.0
HKD2_k127_5170928_351 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000006126 114.0
HKD2_k127_5170928_352 carboxymethylenebutenolidase activity K01061,K06889 - 3.1.1.45 0.00000000000000000000001132 113.0
HKD2_k127_5170928_353 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000001528 104.0
HKD2_k127_5170928_354 Pyrrolo-quinoline quinone - - - 0.0000000000000000000000247 114.0
HKD2_k127_5170928_355 FecR protein - - - 0.00000000000000000000003179 109.0
HKD2_k127_5170928_356 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000006807 105.0
HKD2_k127_5170928_357 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 - 6.3.2.4 0.0000000000000000000001366 108.0
HKD2_k127_5170928_358 Hydrogenase expression formation protein K04653 - - 0.0000000000000000000002178 105.0
HKD2_k127_5170928_359 cellulose binding - - - 0.0000000000000000000004462 111.0
HKD2_k127_5170928_36 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 4.841e-195 619.0
HKD2_k127_5170928_360 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000006426 97.0
HKD2_k127_5170928_361 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.0000000000000000000006581 100.0
HKD2_k127_5170928_363 sequence-specific DNA binding - - - 0.00000000000000000001121 102.0
HKD2_k127_5170928_364 pfkB family carbohydrate kinase K00847,K00852,K18478 - 2.7.1.15,2.7.1.184,2.7.1.4 0.00000000000000000001169 102.0
HKD2_k127_5170928_365 - - - - 0.00000000000000000001835 95.0
HKD2_k127_5170928_366 CHAD domain - - - 0.00000000000000000007992 100.0
HKD2_k127_5170928_367 HEAT repeats - - - 0.0000000000000000008333 93.0
HKD2_k127_5170928_368 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000008713 87.0
HKD2_k127_5170928_369 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.000000000000000001158 101.0
HKD2_k127_5170928_37 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 6.009e-195 639.0
HKD2_k127_5170928_370 antisigma factor binding K04749 - - 0.000000000000000004119 87.0
HKD2_k127_5170928_371 CHAT domain - - - 0.00000000000000003334 97.0
HKD2_k127_5170928_375 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000001183 81.0
HKD2_k127_5170928_376 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000001427 87.0
HKD2_k127_5170928_377 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000001695 81.0
HKD2_k127_5170928_378 - - - - 0.000000000000001741 78.0
HKD2_k127_5170928_38 COG0076 Glutamate decarboxylase and related PLP-dependent K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 605.0
HKD2_k127_5170928_380 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000006787 77.0
HKD2_k127_5170928_381 hydrogenase maturation protease - - - 0.000000000000008147 82.0
HKD2_k127_5170928_382 rod shape-determining protein MreD K03571 - - 0.000000000000008188 83.0
HKD2_k127_5170928_383 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001759 73.0
HKD2_k127_5170928_384 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03591,K07114 - - 0.00000000000004648 83.0
HKD2_k127_5170928_385 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000001392 78.0
HKD2_k127_5170928_386 peptide deformylase activity K01462 - 3.5.1.88 0.0000000000004189 71.0
HKD2_k127_5170928_387 Protein of unknown function (DUF721) - - - 0.0000000000007358 74.0
HKD2_k127_5170928_388 TIGRFAM TonB family protein K03832 - - 0.000000000001285 79.0
HKD2_k127_5170928_389 - - - - 0.000000000001542 72.0
HKD2_k127_5170928_39 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 604.0
HKD2_k127_5170928_390 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.000000000001598 75.0
HKD2_k127_5170928_391 - - - - 0.000000000002683 71.0
HKD2_k127_5170928_392 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000005782 73.0
HKD2_k127_5170928_393 Belongs to the 'phage' integrase family - - - 0.00000000001078 72.0
HKD2_k127_5170928_394 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000002967 66.0
HKD2_k127_5170928_395 chaperone-mediated protein folding K20543 - - 0.00000000006015 72.0
HKD2_k127_5170928_396 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000157 66.0
HKD2_k127_5170928_397 PPIC-type PPIASE domain - - - 0.0000000001594 72.0
HKD2_k127_5170928_398 - - - - 0.0000000003152 72.0
HKD2_k127_5170928_4 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 6.491e-319 996.0
HKD2_k127_5170928_40 lyase activity K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 599.0
HKD2_k127_5170928_400 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000000008074 69.0
HKD2_k127_5170928_402 nitrogen fixation - - - 0.000000004906 64.0
HKD2_k127_5170928_403 Protein of unknown function DUF72 - - - 0.00000003371 65.0
HKD2_k127_5170928_404 Domain of unknown function (DUF4412) - - - 0.00000008175 63.0
HKD2_k127_5170928_406 Protein of unknown function (DUF998) - - - 0.0000004443 56.0
HKD2_k127_5170928_407 Transcriptional regulator, TraR DksA family K06204 - - 0.00000098 55.0
HKD2_k127_5170928_409 membrane - - - 0.000004179 58.0
HKD2_k127_5170928_41 Coenzyme F420-reducing hydrogenase, alpha subunit K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 598.0
HKD2_k127_5170928_411 PFAM Phage late control gene D protein (GPD) K11904 - - 0.000008183 57.0
HKD2_k127_5170928_412 Small Multidrug Resistance protein K03297 - - 0.00001119 52.0
HKD2_k127_5170928_414 - - - - 0.00001226 56.0
HKD2_k127_5170928_417 Putative zinc-finger - - - 0.0001471 52.0
HKD2_k127_5170928_419 interleukin-17C K05491 GO:0001817,GO:0001819,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0003674,GO:0005102,GO:0005125,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0006950,GO:0006952,GO:0006954,GO:0007154,GO:0007165,GO:0007166,GO:0007267,GO:0007275,GO:0008150,GO:0009966,GO:0009987,GO:0010033,GO:0010469,GO:0010646,GO:0019221,GO:0023051,GO:0023052,GO:0030097,GO:0030099,GO:0030154,GO:0030223,GO:0030545,GO:0030851,GO:0031347,GO:0031349,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0034097,GO:0042221,GO:0044421,GO:0048018,GO:0048513,GO:0048518,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0050727,GO:0050729,GO:0050789,GO:0050794,GO:0050896,GO:0051239,GO:0051240,GO:0051716,GO:0065007,GO:0065009,GO:0070887,GO:0071310,GO:0071345,GO:0080134,GO:0097396,GO:0097398,GO:0097400,GO:0098772,GO:1900015,GO:1900017 - 0.0004623 46.0
HKD2_k127_5170928_42 Domain of unknown function (DUF4921) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 595.0
HKD2_k127_5170928_43 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 592.0
HKD2_k127_5170928_44 antibiotic biosynthetic process K01434,K07116 - 3.5.1.11,3.5.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 608.0
HKD2_k127_5170928_45 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 615.0
HKD2_k127_5170928_46 Peptidase family M49 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 591.0
HKD2_k127_5170928_47 methionine adenosyltransferase activity K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 569.0
HKD2_k127_5170928_48 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 576.0
HKD2_k127_5170928_49 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K14660 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 557.0
HKD2_k127_5170928_5 membrane organization K03641,K07277 - - 8.747e-319 1002.0
HKD2_k127_5170928_50 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 553.0
HKD2_k127_5170928_51 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 556.0
HKD2_k127_5170928_52 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 563.0
HKD2_k127_5170928_53 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 555.0
HKD2_k127_5170928_54 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 540.0
HKD2_k127_5170928_55 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 536.0
HKD2_k127_5170928_56 deaminase activity K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 524.0
HKD2_k127_5170928_57 COGs COG1740 Ni Fe-hydrogenase I small subunit K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 525.0
HKD2_k127_5170928_58 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 526.0
HKD2_k127_5170928_59 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 543.0
HKD2_k127_5170928_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.221e-300 956.0
HKD2_k127_5170928_60 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 531.0
HKD2_k127_5170928_61 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 539.0
HKD2_k127_5170928_62 Associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 511.0
HKD2_k127_5170928_63 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 518.0
HKD2_k127_5170928_64 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 515.0
HKD2_k127_5170928_65 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 517.0
HKD2_k127_5170928_66 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 507.0
HKD2_k127_5170928_67 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 508.0
HKD2_k127_5170928_68 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 501.0
HKD2_k127_5170928_69 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 491.0
HKD2_k127_5170928_7 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 2.696e-294 910.0
HKD2_k127_5170928_70 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 485.0
HKD2_k127_5170928_71 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 486.0
HKD2_k127_5170928_72 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 486.0
HKD2_k127_5170928_73 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 477.0
HKD2_k127_5170928_74 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 475.0
HKD2_k127_5170928_75 PFAM penicillin-binding protein transpeptidase K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 491.0
HKD2_k127_5170928_76 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00970,K00974,K00982,K00990,K06950,K15371 - 1.1.1.3,1.4.1.2,2.7.7.19,2.7.7.42,2.7.7.59,2.7.7.72,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 495.0
HKD2_k127_5170928_77 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 476.0
HKD2_k127_5170928_78 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 472.0
HKD2_k127_5170928_79 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 484.0
HKD2_k127_5170928_8 Belongs to the carbamoyltransferase HypF family K04656 - - 7.114e-283 893.0
HKD2_k127_5170928_80 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 468.0
HKD2_k127_5170928_81 Oligoendopeptidase f K01283,K08602 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 473.0
HKD2_k127_5170928_82 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 459.0
HKD2_k127_5170928_83 membrane insertase activity K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 470.0
HKD2_k127_5170928_84 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 479.0
HKD2_k127_5170928_85 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 460.0
HKD2_k127_5170928_86 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
HKD2_k127_5170928_87 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 454.0
HKD2_k127_5170928_88 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 454.0
HKD2_k127_5170928_89 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 451.0
HKD2_k127_5170928_9 urocanate hydratase activity K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 1.759e-282 879.0
HKD2_k127_5170928_90 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 443.0
HKD2_k127_5170928_91 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 442.0
HKD2_k127_5170928_92 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 449.0
HKD2_k127_5170928_93 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 446.0
HKD2_k127_5170928_94 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 455.0
HKD2_k127_5170928_95 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 434.0
HKD2_k127_5170928_96 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 432.0
HKD2_k127_5170928_97 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 454.0
HKD2_k127_5170928_98 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 432.0
HKD2_k127_5170928_99 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 429.0
HKD2_k127_5210826_0 nucleotide-excision repair K03701 - - 0.0 1295.0
HKD2_k127_5210826_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0010033,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030312,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035966,GO:0036094,GO:0040007,GO:0042221,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1098.0
HKD2_k127_5210826_10 IMP dehydrogenase activity K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 2.039e-225 707.0
HKD2_k127_5210826_100 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000006626 124.0
HKD2_k127_5210826_101 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000005575 112.0
HKD2_k127_5210826_102 Transposase - - - 0.0000000000000000000000006435 106.0
HKD2_k127_5210826_104 PFAM Tetratricopeptide TPR_4 - - - 0.000000000000000000002926 108.0
HKD2_k127_5210826_105 HTH-like domain - - - 0.00000000000000000001075 93.0
HKD2_k127_5210826_106 Transglutaminase-like superfamily - - - 0.000000000000000001426 99.0
HKD2_k127_5210826_107 - - - - 0.0000000000000000284 88.0
HKD2_k127_5210826_108 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000009916 89.0
HKD2_k127_5210826_109 M6 family metalloprotease domain - - - 0.000000000000000265 83.0
HKD2_k127_5210826_11 Belongs to the aldehyde dehydrogenase family K00140,K22187 - 1.2.1.18,1.2.1.27 5.563e-214 676.0
HKD2_k127_5210826_110 protein trimerization - - - 0.000000000000005853 82.0
HKD2_k127_5210826_111 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000004697 86.0
HKD2_k127_5210826_112 Two component regulator propeller - - - 0.0000000000001811 75.0
HKD2_k127_5210826_113 - - - - 0.0000000000003319 74.0
HKD2_k127_5210826_114 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000001335 64.0
HKD2_k127_5210826_116 - - - - 0.0000001764 57.0
HKD2_k127_5210826_117 Calcineurin-like phosphoesterase - - - 0.0000002918 63.0
HKD2_k127_5210826_118 PBCV-specific basic adaptor domain K03646 - - 0.0000007356 60.0
HKD2_k127_5210826_119 Protein kinase domain K12132 - 2.7.11.1 0.0000747 47.0
HKD2_k127_5210826_12 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 9.385e-209 663.0
HKD2_k127_5210826_120 Zinc finger, SWIM-type containing 2 K04577,K15716 GO:0000209,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009966,GO:0009967,GO:0009987,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0023051,GO:0023056,GO:0032446,GO:0036211,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043412,GO:0043621,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0061630,GO:0061659,GO:0065007,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1902041,GO:1902043,GO:2001233,GO:2001235,GO:2001236,GO:2001238 2.3.2.27 0.0009201 45.0
HKD2_k127_5210826_13 single-stranded DNA 5'-3' exodeoxyribonuclease activity K07462 - - 4.859e-194 625.0
HKD2_k127_5210826_14 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 593.0
HKD2_k127_5210826_15 NAD binding K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 571.0
HKD2_k127_5210826_16 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 569.0
HKD2_k127_5210826_17 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 563.0
HKD2_k127_5210826_18 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 549.0
HKD2_k127_5210826_19 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821,K03918,K07250,K13524 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 544.0
HKD2_k127_5210826_2 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 2.84e-302 937.0
HKD2_k127_5210826_20 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 505.0
HKD2_k127_5210826_21 PFAM Alpha amylase, catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 487.0
HKD2_k127_5210826_22 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 479.0
HKD2_k127_5210826_23 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 473.0
HKD2_k127_5210826_24 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 469.0
HKD2_k127_5210826_25 ATP synthesis coupled electron transport K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 473.0
HKD2_k127_5210826_26 acyl-CoA dehydrogenase activity K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 463.0
HKD2_k127_5210826_27 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 453.0
HKD2_k127_5210826_28 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007574 469.0
HKD2_k127_5210826_29 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 449.0
HKD2_k127_5210826_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 1.565e-288 908.0
HKD2_k127_5210826_30 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 453.0
HKD2_k127_5210826_31 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 439.0
HKD2_k127_5210826_32 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 439.0
HKD2_k127_5210826_33 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 427.0
HKD2_k127_5210826_34 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00167,K11381,K21417 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 411.0
HKD2_k127_5210826_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 408.0
HKD2_k127_5210826_36 serine-type endopeptidase activity K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 403.0
HKD2_k127_5210826_37 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 412.0
HKD2_k127_5210826_38 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 398.0
HKD2_k127_5210826_39 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007288 386.0
HKD2_k127_5210826_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.28e-285 907.0
HKD2_k127_5210826_40 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 386.0
HKD2_k127_5210826_41 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 367.0
HKD2_k127_5210826_42 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
HKD2_k127_5210826_43 ATPase activity K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 350.0
HKD2_k127_5210826_44 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 352.0
HKD2_k127_5210826_45 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 356.0
HKD2_k127_5210826_46 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 340.0
HKD2_k127_5210826_47 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 338.0
HKD2_k127_5210826_48 isobutyryl-CoA mutase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 335.0
HKD2_k127_5210826_49 Transport permease protein K01992 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006855,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0015562,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0033554,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 343.0
HKD2_k127_5210826_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.751e-273 847.0
HKD2_k127_5210826_50 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 327.0
HKD2_k127_5210826_51 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 325.0
HKD2_k127_5210826_52 Dehydrogenase E1 component K00161,K00166,K11381,K21416 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 329.0
HKD2_k127_5210826_53 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
HKD2_k127_5210826_54 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 310.0
HKD2_k127_5210826_55 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 313.0
HKD2_k127_5210826_56 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 303.0
HKD2_k127_5210826_57 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 304.0
HKD2_k127_5210826_58 Xaa-Pro dipeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 297.0
HKD2_k127_5210826_59 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 280.0
HKD2_k127_5210826_6 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 8.704e-255 803.0
HKD2_k127_5210826_60 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000327 280.0
HKD2_k127_5210826_61 Major facilitator superfamily K08161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000399 282.0
HKD2_k127_5210826_62 belongs to the thioredoxin family K03671,K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000472 275.0
HKD2_k127_5210826_63 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000001958 273.0
HKD2_k127_5210826_64 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 265.0
HKD2_k127_5210826_65 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000003367 258.0
HKD2_k127_5210826_66 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001179 250.0
HKD2_k127_5210826_67 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
HKD2_k127_5210826_68 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000003535 244.0
HKD2_k127_5210826_69 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000006657 234.0
HKD2_k127_5210826_7 NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 2.118e-248 785.0
HKD2_k127_5210826_70 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000000000000000000000000001957 220.0
HKD2_k127_5210826_71 cytoplasmic translational termination K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000002502 217.0
HKD2_k127_5210826_72 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000003564 213.0
HKD2_k127_5210826_73 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000000000000006124 209.0
HKD2_k127_5210826_74 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000874 196.0
HKD2_k127_5210826_75 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.0000000000000000000000000000000000000000000000000000009449 199.0
HKD2_k127_5210826_76 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000003367 191.0
HKD2_k127_5210826_77 - K07164,K22391 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000008563 196.0
HKD2_k127_5210826_78 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000002095 196.0
HKD2_k127_5210826_79 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000002646 187.0
HKD2_k127_5210826_8 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) - - - 4.238e-243 761.0
HKD2_k127_5210826_80 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000001737 187.0
HKD2_k127_5210826_81 phosphoenolpyruvate-dependent sugar phosphotransferase system K02768,K02769,K02770,K02806 - 2.7.1.202 0.000000000000000000000000000000000000000000000001339 178.0
HKD2_k127_5210826_82 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000001066 178.0
HKD2_k127_5210826_83 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000146 177.0
HKD2_k127_5210826_84 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000004636 181.0
HKD2_k127_5210826_85 Conserved hypothetical protein (DUF2461) - - - 0.0000000000000000000000000000000000000000000006546 176.0
HKD2_k127_5210826_86 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000001811 169.0
HKD2_k127_5210826_87 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000003891 156.0
HKD2_k127_5210826_88 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000008191 158.0
HKD2_k127_5210826_89 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000006592 153.0
HKD2_k127_5210826_9 cellulose binding - - - 1.296e-242 780.0
HKD2_k127_5210826_90 carbon-oxygen lyase activity, acting on polysaccharides K18691 - - 0.00000000000000000000000000000000000002257 153.0
HKD2_k127_5210826_91 PspC domain - - - 0.000000000000000000000000000000000003625 148.0
HKD2_k127_5210826_92 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.000000000000000000000000000000002484 138.0
HKD2_k127_5210826_93 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.00000000000000000000000000000001015 131.0
HKD2_k127_5210826_94 - - - - 0.000000000000000000000000000001874 127.0
HKD2_k127_5210826_95 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.000000000000000000000000000005237 126.0
HKD2_k127_5210826_96 Bacterial transcription activator, effector binding domain K13652 - - 0.000000000000000000000000000005278 133.0
HKD2_k127_5210826_97 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000003494 132.0
HKD2_k127_5210826_98 phosphorelay signal transduction system - - - 0.0000000000000000000000000002494 120.0
HKD2_k127_5210826_99 - - - - 0.00000000000000000000000002179 120.0
HKD2_k127_5285601_0 Sodium:solute symporter family - - - 2.057e-308 953.0
HKD2_k127_5285601_1 symporter activity K03307 - - 1.211e-304 941.0
HKD2_k127_5285601_10 Belongs to the glycosyl hydrolase 28 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 535.0
HKD2_k127_5285601_11 Glycosyl Hydrolase Family 88 K15532 - 3.2.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 542.0
HKD2_k127_5285601_12 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 503.0
HKD2_k127_5285601_13 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 501.0
HKD2_k127_5285601_14 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 462.0
HKD2_k127_5285601_15 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 444.0
HKD2_k127_5285601_16 tagaturonate epimerase K21619 - 5.1.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 447.0
HKD2_k127_5285601_17 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 429.0
HKD2_k127_5285601_18 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 432.0
HKD2_k127_5285601_19 Pyridine nucleotide-disulphide oxidoreductase K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 427.0
HKD2_k127_5285601_2 TonB-dependent receptor - - - 1.105e-303 961.0
HKD2_k127_5285601_20 protein secretion K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 429.0
HKD2_k127_5285601_21 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 421.0
HKD2_k127_5285601_22 mannose metabolic process K01191 - 3.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 430.0
HKD2_k127_5285601_23 Domain of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 401.0
HKD2_k127_5285601_24 purine nucleotide biosynthetic process K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 387.0
HKD2_k127_5285601_25 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 381.0
HKD2_k127_5285601_26 Psort location Cytoplasmic, score K01625 - 4.1.2.14,4.1.3.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 376.0
HKD2_k127_5285601_27 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 376.0
HKD2_k127_5285601_28 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 351.0
HKD2_k127_5285601_29 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 327.0
HKD2_k127_5285601_3 glucuronate isomerase activity K01812 GO:0005975,GO:0005996,GO:0006063,GO:0006064,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0019585,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0042839,GO:0042840,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 5.3.1.12 3.476e-198 627.0
HKD2_k127_5285601_30 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 314.0
HKD2_k127_5285601_31 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 317.0
HKD2_k127_5285601_32 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 308.0
HKD2_k127_5285601_33 Pectinesterase K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 302.0
HKD2_k127_5285601_34 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004534 295.0
HKD2_k127_5285601_35 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009214 297.0
HKD2_k127_5285601_36 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006656 284.0
HKD2_k127_5285601_37 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000002033 274.0
HKD2_k127_5285601_38 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008174 250.0
HKD2_k127_5285601_39 GntR family K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
HKD2_k127_5285601_4 pfkB family carbohydrate kinase - - - 2.294e-197 619.0
HKD2_k127_5285601_40 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000005528 209.0
HKD2_k127_5285601_41 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000009445 168.0
HKD2_k127_5285601_42 Domain of unknown function (DUF4269) - - - 0.00000000000000000000000000000404 128.0
HKD2_k127_5285601_43 - - - - 0.00000000000000006424 95.0
HKD2_k127_5285601_44 protein secretion K20276 - - 0.0000000000000009791 91.0
HKD2_k127_5285601_45 domain, Protein - - - 0.000451 53.0
HKD2_k127_5285601_5 Zn_pept - - - 2.297e-195 623.0
HKD2_k127_5285601_6 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 2.605e-195 623.0
HKD2_k127_5285601_7 Oxidoreductase family, C-terminal alpha/beta domain - - - 7.186e-194 617.0
HKD2_k127_5285601_8 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 612.0
HKD2_k127_5285601_9 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 546.0
HKD2_k127_5362457_0 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001763 275.0
HKD2_k127_5362457_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000001042 226.0
HKD2_k127_5362457_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000008993 180.0
HKD2_k127_5362457_3 Metallopeptidase family M24 K01262 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9 0.00001208 48.0
HKD2_k127_5615212_0 Aminotransferase K21572 - - 0.0 1915.0
HKD2_k127_5615212_1 membrane organization K03641,K07277 - - 0.0 1045.0
HKD2_k127_5615212_10 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 2.132e-221 722.0
HKD2_k127_5615212_100 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000001029 244.0
HKD2_k127_5615212_101 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000001291 237.0
HKD2_k127_5615212_102 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 235.0
HKD2_k127_5615212_103 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HKD2_k127_5615212_104 isomerase activity K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000002239 234.0
HKD2_k127_5615212_105 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000001245 231.0
HKD2_k127_5615212_106 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760,K00939,K15780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.8,2.7.4.3,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000006822 224.0
HKD2_k127_5615212_107 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000004451 220.0
HKD2_k127_5615212_109 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000003687 222.0
HKD2_k127_5615212_11 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 4.361e-220 691.0
HKD2_k127_5615212_110 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000001775 214.0
HKD2_k127_5615212_111 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000043 215.0
HKD2_k127_5615212_112 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000001224 211.0
HKD2_k127_5615212_113 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000088 211.0
HKD2_k127_5615212_114 Membrane - - - 0.000000000000000000000000000000000000000000000000000002288 207.0
HKD2_k127_5615212_115 DNA-templated transcription, initiation K03088 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005618,GO:0005623,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0043254,GO:0044087,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000005666 196.0
HKD2_k127_5615212_116 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000002122 201.0
HKD2_k127_5615212_117 - K07283 - - 0.000000000000000000000000000000000000000000000000004435 192.0
HKD2_k127_5615212_118 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000009197 190.0
HKD2_k127_5615212_119 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000004365 188.0
HKD2_k127_5615212_12 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.774e-203 640.0
HKD2_k127_5615212_120 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000001127 185.0
HKD2_k127_5615212_121 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000003439 179.0
HKD2_k127_5615212_122 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000287 168.0
HKD2_k127_5615212_123 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.00000000000000000000000000000000000000000000645 174.0
HKD2_k127_5615212_125 PFAM GCN5-related N-acetyltransferase K02348 - - 0.000000000000000000000000000000000000000001626 161.0
HKD2_k127_5615212_127 heat shock protein binding - - - 0.0000000000000000000000000000000000000001987 163.0
HKD2_k127_5615212_128 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000004274 155.0
HKD2_k127_5615212_129 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000001051 154.0
HKD2_k127_5615212_13 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 611.0
HKD2_k127_5615212_130 Outer membrane transport energization protein ExbD - - - 0.00000000000000000000000000000000000001236 150.0
HKD2_k127_5615212_131 amine dehydrogenase activity K21449 - - 0.00000000000000000000000000000000000009971 149.0
HKD2_k127_5615212_132 Methyltransferase - - - 0.000000000000000000000000000000000001967 147.0
HKD2_k127_5615212_133 rRNA methyltransferase - - - 0.00000000000000000000000000000000000449 151.0
HKD2_k127_5615212_134 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000004683 153.0
HKD2_k127_5615212_135 ABC-type phosphate transport system periplasmic K02040 - - 0.000000000000000000000000000000000007478 149.0
HKD2_k127_5615212_136 water channel activity K02440,K06188 - - 0.000000000000000000000000000000000007563 146.0
HKD2_k127_5615212_137 beta-galactosidase activity - - - 0.00000000000000000000000000000000001444 150.0
HKD2_k127_5615212_138 PFAM Biopolymer transport protein ExbD TolR - - - 0.00000000000000000000000000000000001744 140.0
HKD2_k127_5615212_139 NUDIX domain - - - 0.00000000000000000000000000000000006783 140.0
HKD2_k127_5615212_14 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 607.0
HKD2_k127_5615212_140 Peptidase, M16 K07263 - - 0.0000000000000000000000000000000002334 136.0
HKD2_k127_5615212_141 Bacterial regulatory proteins, tetR family K18301 - - 0.00000000000000000000000000000005809 133.0
HKD2_k127_5615212_142 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000000000000000002471 123.0
HKD2_k127_5615212_143 - - - - 0.000000000000000000000000000005457 127.0
HKD2_k127_5615212_144 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000006405 125.0
HKD2_k127_5615212_145 long-chain fatty acid transport protein - - - 0.0000000000000000000000000001368 132.0
HKD2_k127_5615212_146 - - - - 0.0000000000000000000000000001487 124.0
HKD2_k127_5615212_147 - - - - 0.000000000000000000000000003953 122.0
HKD2_k127_5615212_148 pectinesterase activity - - - 0.0000000000000000000000002143 115.0
HKD2_k127_5615212_15 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 603.0
HKD2_k127_5615212_150 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000039 113.0
HKD2_k127_5615212_151 RNA recognition motif - - - 0.0000000000000000000000005354 106.0
HKD2_k127_5615212_152 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000427 105.0
HKD2_k127_5615212_153 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000001833 105.0
HKD2_k127_5615212_154 Tetratricopeptide repeat - - - 0.0000000000000000000002892 112.0
HKD2_k127_5615212_155 phosphorelay signal transduction system - - - 0.0000000000000000000008665 100.0
HKD2_k127_5615212_156 Transcriptional regulatory protein, C terminal K07669,K07672 - - 0.0000000000000000000009234 99.0
HKD2_k127_5615212_157 OsmC-like protein - - - 0.00000000000000000001565 103.0
HKD2_k127_5615212_158 - - - - 0.0000000000000000002404 99.0
HKD2_k127_5615212_159 antisigma factor binding K04749 - - 0.00000000000000000165 89.0
HKD2_k127_5615212_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 597.0
HKD2_k127_5615212_160 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000001862 90.0
HKD2_k127_5615212_161 - - - - 0.000000000000000005046 91.0
HKD2_k127_5615212_162 Carbohydrate family 9 binding domain-like - - - 0.00000000000000001495 91.0
HKD2_k127_5615212_164 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000007165 83.0
HKD2_k127_5615212_165 - - - - 0.00000000000009147 81.0
HKD2_k127_5615212_166 - - - - 0.0000000000003949 78.0
HKD2_k127_5615212_168 - - - - 0.000000000002134 75.0
HKD2_k127_5615212_169 - - - - 0.00000000004172 73.0
HKD2_k127_5615212_17 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 585.0
HKD2_k127_5615212_170 Domain of unknown function (DUF4203) - - - 0.0000000001426 68.0
HKD2_k127_5615212_171 - - - - 0.0000000004035 64.0
HKD2_k127_5615212_172 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000005323 64.0
HKD2_k127_5615212_174 - - - - 0.0000005342 57.0
HKD2_k127_5615212_175 DinB family - - - 0.0000008284 57.0
HKD2_k127_5615212_178 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00009782 53.0
HKD2_k127_5615212_18 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 589.0
HKD2_k127_5615212_180 - - - - 0.0002543 44.0
HKD2_k127_5615212_19 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573,K12585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 591.0
HKD2_k127_5615212_2 GxGYxYP putative glycoside hydrolase C-terminal domain K03088 - - 2.118e-298 929.0
HKD2_k127_5615212_20 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 572.0
HKD2_k127_5615212_21 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 563.0
HKD2_k127_5615212_22 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 552.0
HKD2_k127_5615212_23 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 561.0
HKD2_k127_5615212_24 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 519.0
HKD2_k127_5615212_25 GTP binding K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 511.0
HKD2_k127_5615212_26 cystathionine gamma-synthase activity K01758,K01760,K01761 - 4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 503.0
HKD2_k127_5615212_27 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 500.0
HKD2_k127_5615212_28 Cytochrome C-type biogenesis protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 514.0
HKD2_k127_5615212_29 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 507.0
HKD2_k127_5615212_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.982e-294 921.0
HKD2_k127_5615212_30 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 488.0
HKD2_k127_5615212_31 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 490.0
HKD2_k127_5615212_32 Sigma-54 interaction domain K11384 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 488.0
HKD2_k127_5615212_33 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 474.0
HKD2_k127_5615212_34 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 486.0
HKD2_k127_5615212_35 peptidyl-prolyl cis-trans isomerase activity K01802,K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 470.0
HKD2_k127_5615212_36 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 458.0
HKD2_k127_5615212_37 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 447.0
HKD2_k127_5615212_38 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 490.0
HKD2_k127_5615212_39 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 454.0
HKD2_k127_5615212_4 Dipeptidyl peptidase IV (DPP IV) K01278 - 3.4.14.5 2.082e-271 854.0
HKD2_k127_5615212_40 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K21624 - 4.2.1.171 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 447.0
HKD2_k127_5615212_41 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 450.0
HKD2_k127_5615212_42 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009279 442.0
HKD2_k127_5615212_43 Glycosyltransferase like family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 429.0
HKD2_k127_5615212_44 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 421.0
HKD2_k127_5615212_45 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 428.0
HKD2_k127_5615212_46 PFAM Methanol-cobalamin methyltransferase B subunit K04480 - 2.1.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 420.0
HKD2_k127_5615212_47 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175,K00187 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 407.0
HKD2_k127_5615212_48 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 434.0
HKD2_k127_5615212_49 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 406.0
HKD2_k127_5615212_5 peptidase K01278 - 3.4.14.5 1.623e-259 820.0
HKD2_k127_5615212_50 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 413.0
HKD2_k127_5615212_51 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 409.0
HKD2_k127_5615212_52 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 409.0
HKD2_k127_5615212_53 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 406.0
HKD2_k127_5615212_54 4Fe-4S binding domain K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 391.0
HKD2_k127_5615212_55 Tat pathway signal sequence domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 391.0
HKD2_k127_5615212_56 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 408.0
HKD2_k127_5615212_57 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 384.0
HKD2_k127_5615212_58 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 398.0
HKD2_k127_5615212_59 lactate racemase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 382.0
HKD2_k127_5615212_6 Domain of unknown function (DUF5127) - - - 1.046e-255 811.0
HKD2_k127_5615212_60 Belongs to the GHMP kinase family K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 380.0
HKD2_k127_5615212_61 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 384.0
HKD2_k127_5615212_62 Fatty acid desaturase K03921 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.14.19.11,1.14.19.2,1.14.19.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 374.0
HKD2_k127_5615212_63 Histidine kinase K07709,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 374.0
HKD2_k127_5615212_64 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 370.0
HKD2_k127_5615212_65 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 359.0
HKD2_k127_5615212_66 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 359.0
HKD2_k127_5615212_67 Glycogen debranching enzyme, glucanotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 367.0
HKD2_k127_5615212_68 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 359.0
HKD2_k127_5615212_69 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 342.0
HKD2_k127_5615212_7 Prokaryotic cytochrome b561 - - - 1.696e-252 796.0
HKD2_k127_5615212_70 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 347.0
HKD2_k127_5615212_71 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
HKD2_k127_5615212_72 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 340.0
HKD2_k127_5615212_73 denitrification pathway - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 334.0
HKD2_k127_5615212_74 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 334.0
HKD2_k127_5615212_75 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 321.0
HKD2_k127_5615212_76 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 320.0
HKD2_k127_5615212_77 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 321.0
HKD2_k127_5615212_78 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 309.0
HKD2_k127_5615212_79 protein secretion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 340.0
HKD2_k127_5615212_8 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.418e-248 787.0
HKD2_k127_5615212_80 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 302.0
HKD2_k127_5615212_81 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 303.0
HKD2_k127_5615212_82 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000121 291.0
HKD2_k127_5615212_83 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 291.0
HKD2_k127_5615212_84 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001237 287.0
HKD2_k127_5615212_85 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002098 295.0
HKD2_k127_5615212_86 Glycosyl transferase, family 2 K20444 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001508 282.0
HKD2_k127_5615212_87 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002389 280.0
HKD2_k127_5615212_88 lipoprotein YddW precursor K01189 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009956 283.0
HKD2_k127_5615212_89 MobA-like NTP transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006089 267.0
HKD2_k127_5615212_9 formate dehydrogenase - - - 1.485e-235 748.0
HKD2_k127_5615212_90 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001474 266.0
HKD2_k127_5615212_91 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00177,K00187 - 1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002578 258.0
HKD2_k127_5615212_92 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
HKD2_k127_5615212_93 Domain of unknown function (DUF5109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002271 259.0
HKD2_k127_5615212_94 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000005035 256.0
HKD2_k127_5615212_95 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001284 256.0
HKD2_k127_5615212_96 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000012 255.0
HKD2_k127_5615212_97 Domain of unknown function (DUF1835) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001224 254.0
HKD2_k127_5615212_98 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001351 248.0
HKD2_k127_5615212_99 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003135 245.0
HKD2_k127_5816669_0 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0 2154.0
HKD2_k127_5816669_1 AMP-binding enzyme - - - 0.0 1555.0
HKD2_k127_5816669_2 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 1.15e-221 707.0
HKD2_k127_5926060_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1074.0
HKD2_k127_5926060_1 Belongs to the peptidase S8 family - - - 1.113e-276 894.0
HKD2_k127_5926060_10 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009345,GO:0009987,GO:0010467,GO:0016070,GO:0016594,GO:0016597,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0042165,GO:0042802,GO:0042803,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046983,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.14 3.248e-200 633.0
HKD2_k127_5926060_11 Major facilitator Superfamily K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 571.0
HKD2_k127_5926060_12 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 495.0
HKD2_k127_5926060_13 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 466.0
HKD2_k127_5926060_14 ATPase activity K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 449.0
HKD2_k127_5926060_15 phosphoglucosamine mutase activity K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 450.0
HKD2_k127_5926060_16 drug transmembrane transporter activity K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 441.0
HKD2_k127_5926060_17 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 428.0
HKD2_k127_5926060_18 PFAM Aminotransferase class I and II K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 432.0
HKD2_k127_5926060_19 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 432.0
HKD2_k127_5926060_2 TonB-dependent receptor - - - 2.783e-268 858.0
HKD2_k127_5926060_20 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 421.0
HKD2_k127_5926060_21 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 396.0
HKD2_k127_5926060_22 Binding-protein-dependent transport system inner membrane component K02025,K15770,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 371.0
HKD2_k127_5926060_23 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 375.0
HKD2_k127_5926060_24 maltose binding K15770,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 374.0
HKD2_k127_5926060_25 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 381.0
HKD2_k127_5926060_26 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 382.0
HKD2_k127_5926060_27 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 366.0
HKD2_k127_5926060_28 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 360.0
HKD2_k127_5926060_29 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 349.0
HKD2_k127_5926060_3 PFAM ABC transporter transmembrane K06147 - - 7.042e-268 835.0
HKD2_k127_5926060_30 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 323.0
HKD2_k127_5926060_31 Binding-protein-dependent transport system inner membrane component K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 326.0
HKD2_k127_5926060_32 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 328.0
HKD2_k127_5926060_33 helix_turn _helix lactose operon repressor K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 325.0
HKD2_k127_5926060_34 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 315.0
HKD2_k127_5926060_35 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K11072 - 3.6.3.30,3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 319.0
HKD2_k127_5926060_36 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 321.0
HKD2_k127_5926060_37 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 289.0
HKD2_k127_5926060_38 lipolytic protein G-D-S-L family K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009381 285.0
HKD2_k127_5926060_39 Glycosyl transferase, family 9 K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008717 270.0
HKD2_k127_5926060_4 TonB-dependent receptor - - - 3.895e-252 803.0
HKD2_k127_5926060_40 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001683 271.0
HKD2_k127_5926060_41 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001959 269.0
HKD2_k127_5926060_42 Glycosyl transferase, family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001758 256.0
HKD2_k127_5926060_43 regulation of microtubule-based process K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008668 254.0
HKD2_k127_5926060_44 Belongs to the 'phage' integrase family K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002845 251.0
HKD2_k127_5926060_45 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002756 241.0
HKD2_k127_5926060_46 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000001718 228.0
HKD2_k127_5926060_47 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000002515 226.0
HKD2_k127_5926060_48 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.0000000000000000000000000000000000000000000000000000000000001981 217.0
HKD2_k127_5926060_49 thiamine-phosphate kinase activity K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000003914 224.0
HKD2_k127_5926060_5 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 4.164e-239 764.0
HKD2_k127_5926060_50 - - - - 0.00000000000000000000000000000000000000000000000000000000001529 224.0
HKD2_k127_5926060_51 lipolytic protein G-D-S-L family K00612 - - 0.00000000000000000000000000000000000000000000000000000000001651 229.0
HKD2_k127_5926060_52 COGs COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000000000000000005803 211.0
HKD2_k127_5926060_53 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000039 210.0
HKD2_k127_5926060_54 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000006941 202.0
HKD2_k127_5926060_55 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000001933 207.0
HKD2_k127_5926060_56 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000007547 199.0
HKD2_k127_5926060_57 ZIP Zinc transporter K07238,K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000001229 195.0
HKD2_k127_5926060_58 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000000000000000000009535 196.0
HKD2_k127_5926060_59 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000004688 187.0
HKD2_k127_5926060_6 (ABC) transporter K02021,K06147,K06148,K11085 - - 8.681e-231 733.0
HKD2_k127_5926060_60 peptidyl-prolyl cis-trans isomerase activity K01802,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000009176 198.0
HKD2_k127_5926060_61 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000007666 176.0
HKD2_k127_5926060_62 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000003932 172.0
HKD2_k127_5926060_63 antisigma factor binding K04749,K06378 - - 0.000000000000000000000000000000000000000003121 158.0
HKD2_k127_5926060_64 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000002981 165.0
HKD2_k127_5926060_65 nucleotide catabolic process K01181,K07004 - 3.2.1.8 0.00000000000000000000000000000000000000005931 173.0
HKD2_k127_5926060_66 Rossmann-like domain - - - 0.00000000000000000000000000000000000001597 157.0
HKD2_k127_5926060_67 Sigma-70 region 2 - - - 0.0000000000000000000000000000000000004285 146.0
HKD2_k127_5926060_68 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000009625 141.0
HKD2_k127_5926060_69 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000000000000007253 136.0
HKD2_k127_5926060_7 Protein of unknown function, DUF255 K06888 - - 2.536e-228 727.0
HKD2_k127_5926060_70 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000001019 132.0
HKD2_k127_5926060_71 amino acid K03294 - - 0.000000000000000000000000000001295 123.0
HKD2_k127_5926060_72 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000001582 123.0
HKD2_k127_5926060_73 PFAM response regulator receiver K02483,K07658 - - 0.00000000000000000000000000004311 128.0
HKD2_k127_5926060_74 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.000000000000000000000000003572 119.0
HKD2_k127_5926060_75 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000007524 119.0
HKD2_k127_5926060_76 Domain of unknown function (DUF1844) - - - 0.00000000000000000002539 93.0
HKD2_k127_5926060_77 O-Antigen ligase - - - 0.0000000000000000001616 102.0
HKD2_k127_5926060_78 outer membrane protein protective antigen - - - 0.0000000000000004671 91.0
HKD2_k127_5926060_79 Tetratricopeptide repeat protein - - - 0.00000000000003148 82.0
HKD2_k127_5926060_8 hydrolase activity, hydrolyzing O-glycosyl compounds K01337 - 3.4.21.50 2.126e-222 728.0
HKD2_k127_5926060_80 - - - - 0.00000000000005178 82.0
HKD2_k127_5926060_81 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000006944 79.0
HKD2_k127_5926060_82 Protein of unknown function (DUF4013) - - - 0.000000002751 68.0
HKD2_k127_5926060_83 Cytochrome c - - - 0.000000008289 62.0
HKD2_k127_5926060_84 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00001472 57.0
HKD2_k127_5926060_9 PFAM alpha amylase, catalytic region - - - 2.334e-209 668.0
HKD2_k127_6057502_0 synthetase (ADP forming), alpha K01905,K22224 - 6.2.1.13 1.641e-285 893.0
HKD2_k127_6057502_1 ammonia-lyase activity K01745 - 4.3.1.3 7.591e-271 840.0
HKD2_k127_6057502_10 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000002819 138.0
HKD2_k127_6057502_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000001827 104.0
HKD2_k127_6057502_12 Polysaccharide biosynthesis protein - - - 0.0000000000000303 85.0
HKD2_k127_6057502_2 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K01057,K02564 GO:0003674,GO:0003824,GO:0004342,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006040,GO:0006044,GO:0006046,GO:0006047,GO:0006048,GO:0006054,GO:0006082,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016054,GO:0016787,GO:0016853,GO:0016860,GO:0016861,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0019239,GO:0019262,GO:0019438,GO:0019752,GO:0034641,GO:0034654,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046348,GO:0046349,GO:0046395,GO:0046483,GO:0055086,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901362,GO:1901575,GO:1901576 3.1.1.31,3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 444.0
HKD2_k127_6057502_3 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 370.0
HKD2_k127_6057502_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001164 269.0
HKD2_k127_6057502_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000001728 236.0
HKD2_k127_6057502_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000006191 215.0
HKD2_k127_6057502_7 PFAM Glycosyl transferase, group 1 K12996 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000003821 220.0
HKD2_k127_6057502_8 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000001139 225.0
HKD2_k127_6057502_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000004175 205.0
HKD2_k127_6290751_0 aconitate hydratase activity K01681 - 4.2.1.3 0.0 1119.0
HKD2_k127_6290751_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.533e-311 980.0
HKD2_k127_6290751_10 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 556.0
HKD2_k127_6290751_100 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.00000000005006 73.0
HKD2_k127_6290751_101 - - - - 0.00000000008397 64.0
HKD2_k127_6290751_102 Domain of unknown function (DUF4412) - - - 0.0000000001161 71.0
HKD2_k127_6290751_103 TonB-dependent Receptor Plug Domain K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.000000006004 69.0
HKD2_k127_6290751_104 - - - - 0.0000000634 59.0
HKD2_k127_6290751_105 bacterial (prokaryotic) histone like domain - - - 0.0000004588 55.0
HKD2_k127_6290751_106 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03749 - - 0.00001147 57.0
HKD2_k127_6290751_107 Putative porin - - - 0.00005574 56.0
HKD2_k127_6290751_108 TonB-dependent receptor - - - 0.00005593 56.0
HKD2_k127_6290751_109 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00008302 54.0
HKD2_k127_6290751_11 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 514.0
HKD2_k127_6290751_110 - - - - 0.0005763 44.0
HKD2_k127_6290751_12 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 505.0
HKD2_k127_6290751_13 porphobilinogen synthase activity K01698 GO:0000287,GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 481.0
HKD2_k127_6290751_14 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 492.0
HKD2_k127_6290751_15 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 477.0
HKD2_k127_6290751_16 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 471.0
HKD2_k127_6290751_17 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 468.0
HKD2_k127_6290751_18 peptidase activity, acting on L-amino acid peptides K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 489.0
HKD2_k127_6290751_19 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 445.0
HKD2_k127_6290751_2 GTPase activity K03596 - - 9.048e-299 928.0
HKD2_k127_6290751_20 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 449.0
HKD2_k127_6290751_21 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 465.0
HKD2_k127_6290751_22 heat shock protein binding K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 430.0
HKD2_k127_6290751_23 PFAM Spore coat protein CotH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 424.0
HKD2_k127_6290751_24 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 372.0
HKD2_k127_6290751_25 arabinose-5-phosphate isomerase activity K01627,K03281,K06041 - 2.5.1.55,5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 373.0
HKD2_k127_6290751_26 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 374.0
HKD2_k127_6290751_27 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 360.0
HKD2_k127_6290751_28 involved in lipopolysaccharide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 370.0
HKD2_k127_6290751_29 coproporphyrinogen oxidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 349.0
HKD2_k127_6290751_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 3.621e-253 810.0
HKD2_k127_6290751_30 3-deoxy-8-phosphooctulonate synthase activity K01627 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005996,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008676,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016043,GO:0016051,GO:0016053,GO:0016740,GO:0016765,GO:0019294,GO:0019752,GO:0022607,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046394,GO:0046400,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 342.0
HKD2_k127_6290751_31 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 349.0
HKD2_k127_6290751_32 PFAM General secretory system II protein E domain protein K11740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 347.0
HKD2_k127_6290751_33 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 346.0
HKD2_k127_6290751_34 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 340.0
HKD2_k127_6290751_35 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 334.0
HKD2_k127_6290751_36 DNA mediated transformation K02342,K03168,K03703,K04096 - 2.7.7.7,5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 331.0
HKD2_k127_6290751_37 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 316.0
HKD2_k127_6290751_38 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 329.0
HKD2_k127_6290751_39 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 303.0
HKD2_k127_6290751_4 Peptidase S46 - - - 5.255e-253 798.0
HKD2_k127_6290751_40 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 308.0
HKD2_k127_6290751_41 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 313.0
HKD2_k127_6290751_42 signal peptide processing K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002554 275.0
HKD2_k127_6290751_43 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001236 265.0
HKD2_k127_6290751_44 Belongs to the 5'-nucleotidase family K01081,K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000005102 269.0
HKD2_k127_6290751_45 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008675 258.0
HKD2_k127_6290751_46 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
HKD2_k127_6290751_47 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004002 270.0
HKD2_k127_6290751_48 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000001707 252.0
HKD2_k127_6290751_49 long-chain fatty acid transporting porin activity K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000001198 237.0
HKD2_k127_6290751_5 ftsk spoiiie K03466 - - 4.745e-223 718.0
HKD2_k127_6290751_50 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000003545 230.0
HKD2_k127_6290751_51 D-glycero-D-manno-heptose 7-phosphate metabolic process K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000139 230.0
HKD2_k127_6290751_52 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000003839 229.0
HKD2_k127_6290751_53 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000001327 251.0
HKD2_k127_6290751_54 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000004671 229.0
HKD2_k127_6290751_55 bacteriocin transport K03561 - - 0.000000000000000000000000000000000000000000000000000000000007343 214.0
HKD2_k127_6290751_56 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.0000000000000000000000000000000000000000000000000000000000511 214.0
HKD2_k127_6290751_58 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000002756 196.0
HKD2_k127_6290751_59 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000009816 199.0
HKD2_k127_6290751_6 isocitrate dehydrogenase activity K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 3.325e-203 639.0
HKD2_k127_6290751_60 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000002129 184.0
HKD2_k127_6290751_61 Protein of unknown function (DUF3109) - - - 0.00000000000000000000000000000000000000000000002491 176.0
HKD2_k127_6290751_62 Domain of unknown function (DUF4956) - - - 0.0000000000000000000000000000000000000000000005671 173.0
HKD2_k127_6290751_63 PAS fold - - - 0.000000000000000000000000000000000000000000001019 185.0
HKD2_k127_6290751_64 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000009658 171.0
HKD2_k127_6290751_65 Belongs to the UPF0403 family - - - 0.0000000000000000000000000000000000000000001924 169.0
HKD2_k127_6290751_66 cellulose binding - - - 0.0000000000000000000000000000000000000000002407 184.0
HKD2_k127_6290751_67 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K02652,K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0017076,GO:0030234,GO:0030312,GO:0030554,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036094,GO:0040007,GO:0042594,GO:0044464,GO:0050790,GO:0050896,GO:0051082,GO:0051716,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0071496,GO:0071944,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000003536 158.0
HKD2_k127_6290751_68 DinB family - - - 0.0000000000000000000000000000000000000009615 153.0
HKD2_k127_6290751_69 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.000000000000000000000000000000000000001319 150.0
HKD2_k127_6290751_7 Major Facilitator Superfamily K02445 - - 1.098e-201 636.0
HKD2_k127_6290751_70 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.00000000000000000000000000000000000005972 150.0
HKD2_k127_6290751_71 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000000003113 146.0
HKD2_k127_6290751_72 cytokinin biosynthetic process K06966 - 3.2.2.10 0.000000000000000000000000000000000002046 145.0
HKD2_k127_6290751_73 VTC domain - - - 0.000000000000000000000000000000000006499 148.0
HKD2_k127_6290751_74 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K12736 GO:0000375,GO:0000377,GO:0000398,GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005681,GO:0006139,GO:0006396,GO:0006397,GO:0006464,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016018,GO:0016070,GO:0016071,GO:0016604,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031974,GO:0031981,GO:0032991,GO:0033218,GO:0034641,GO:0036211,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0070013,GO:0071013,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1902494,GO:1990904 5.2.1.8 0.0000000000000000000000000000000002691 140.0
HKD2_k127_6290751_76 TPR repeat - - - 0.00000000000000000000000000000165 135.0
HKD2_k127_6290751_77 long-chain fatty acid transport protein - - - 0.0000000000000000000000000003107 128.0
HKD2_k127_6290751_78 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000001162 119.0
HKD2_k127_6290751_79 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000005329 112.0
HKD2_k127_6290751_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 6.405e-194 625.0
HKD2_k127_6290751_80 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000001984 113.0
HKD2_k127_6290751_81 cellulose binding - - - 0.000000000000000000000004865 120.0
HKD2_k127_6290751_82 response regulator K02481,K07715 - - 0.00000000000000000000002689 103.0
HKD2_k127_6290751_83 HEAT repeats - - - 0.00000000000000000000002752 111.0
HKD2_k127_6290751_84 DinB superfamily - - - 0.00000000000000000000007132 106.0
HKD2_k127_6290751_85 Tetratricopeptide repeat - - - 0.0000000000000000000003383 109.0
HKD2_k127_6290751_86 FmdB family - - - 0.0000000000000000000005467 99.0
HKD2_k127_6290751_87 cellulose binding - - - 0.000000000000000000007647 109.0
HKD2_k127_6290751_88 - - - - 0.0000000000000000002102 104.0
HKD2_k127_6290751_89 - - - - 0.0000000000000000003518 97.0
HKD2_k127_6290751_9 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 593.0
HKD2_k127_6290751_90 Helix-hairpin-helix motif K02237 - - 0.0000000000000001633 85.0
HKD2_k127_6290751_91 Biopolymer transport protein ExbD/TolR K03559 - - 0.0000000000000002752 83.0
HKD2_k127_6290751_92 - - - - 0.0000000000000009311 87.0
HKD2_k127_6290751_93 energy transducer activity K03832 - - 0.00000000000000123 86.0
HKD2_k127_6290751_94 - - - - 0.000000000000002108 79.0
HKD2_k127_6290751_97 Phosphoserine phosphatase - - - 0.0000000000003264 80.0
HKD2_k127_6290751_98 OstA-like protein - - - 0.0000000000004379 81.0
HKD2_k127_6290751_99 Putative adhesin - - - 0.0000000000005245 81.0
HKD2_k127_6608743_0 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K00404,K00405,K15862 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.0 1177.0
HKD2_k127_6608743_1 mercury ion transmembrane transporter activity K01533,K17686 GO:0003674,GO:0003824,GO:0005215,GO:0005388,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0008150,GO:0008324,GO:0015075,GO:0015085,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0070588,GO:0070838,GO:0071944,GO:0072511,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.4,3.6.3.54 9.338e-234 748.0
HKD2_k127_6608743_10 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009482 252.0
HKD2_k127_6608743_11 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000002047 222.0
HKD2_k127_6608743_12 Cytochrome c K00406 - - 0.000000000000000000000000000000000000000000000000000000000007707 217.0
HKD2_k127_6608743_13 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000004427 186.0
HKD2_k127_6608743_14 Biogenesis protein K09792 - - 0.000000000000000000000000000000000000000000000009092 181.0
HKD2_k127_6608743_15 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000001615 195.0
HKD2_k127_6608743_16 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.00000000000000000000000000000000000001032 150.0
HKD2_k127_6608743_17 Methyltransferase domain - - - 0.000000000000000000000000000000000001047 149.0
HKD2_k127_6608743_18 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000003729 138.0
HKD2_k127_6608743_19 Transcriptional regulator K21903 - - 0.000000000000000000000000000001001 124.0
HKD2_k127_6608743_2 Heavy metal translocating P-type atpase K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 617.0
HKD2_k127_6608743_20 holo-[acyl-carrier-protein] synthase activity K00950,K00997,K01207,K01775,K06133,K06925,K18014 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.6.3,2.7.8.7,3.2.1.52,4.3.1.14,5.1.1.1 0.000000000000000000000000000006067 122.0
HKD2_k127_6608743_21 PFAM Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000008481 126.0
HKD2_k127_6608743_22 3-demethylubiquinone-9 3-O-methyltransferase activity K15257 - - 0.0000000000000000000000000003885 129.0
HKD2_k127_6608743_24 Polysaccharide biosynthesis protein - - - 0.00000000000001245 87.0
HKD2_k127_6608743_25 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.00000000002762 68.0
HKD2_k127_6608743_26 FixH - - - 0.00000000004386 70.0
HKD2_k127_6608743_27 Methyltransferase domain - - - 0.00000098 53.0
HKD2_k127_6608743_3 4 iron, 4 sulfur cluster binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 560.0
HKD2_k127_6608743_30 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.0004424 45.0
HKD2_k127_6608743_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 424.0
HKD2_k127_6608743_5 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
HKD2_k127_6608743_6 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 378.0
HKD2_k127_6608743_7 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 335.0
HKD2_k127_6608743_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 303.0
HKD2_k127_6608743_9 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003345 280.0
HKD2_k127_6679078_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003907 290.0
HKD2_k127_6679078_1 Ferritin-like domain - - - 0.0000000000000000000000000000000000001133 143.0
HKD2_k127_6679078_2 cellulose binding - - - 0.00000000000000000000001456 116.0
HKD2_k127_6712241_0 Sulfatase K01130 - 3.1.6.1 0.0 1255.0
HKD2_k127_6712241_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 - 2.7.6.5,3.1.7.2 1.523e-296 926.0
HKD2_k127_6712241_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 393.0
HKD2_k127_6712241_11 Peptidase, M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 396.0
HKD2_k127_6712241_12 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 314.0
HKD2_k127_6712241_13 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003755 282.0
HKD2_k127_6712241_14 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002655 266.0
HKD2_k127_6712241_15 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004845,GO:0004849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016763,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000001058 253.0
HKD2_k127_6712241_16 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000004144 231.0
HKD2_k127_6712241_17 Belongs to the cytidylate kinase family. Type 1 subfamily K00800,K00945,K03977,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.19,2.7.4.25,6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000002767 230.0
HKD2_k127_6712241_18 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000007291 218.0
HKD2_k127_6712241_19 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000299 209.0
HKD2_k127_6712241_2 polyribonucleotide nucleotidyltransferase activity K02945,K03527,K07571,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 8.609e-257 804.0
HKD2_k127_6712241_20 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437 - 2.1.1.185,2.1.1.34 0.000000000000000000000000000000000000000000000000000001029 201.0
HKD2_k127_6712241_21 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000001039 198.0
HKD2_k127_6712241_22 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000000000000000000000000000000000000000000001965 203.0
HKD2_k127_6712241_23 - - - - 0.00000000000000000000000000000000000000000000000000007553 196.0
HKD2_k127_6712241_24 - - - - 0.0000000000000000000000000000000000000000000000215 188.0
HKD2_k127_6712241_25 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000000000000000000000000001974 155.0
HKD2_k127_6712241_26 - - - - 0.00000000000000000000000000000000001238 146.0
HKD2_k127_6712241_27 response regulator, receiver - - - 0.00000000000000000000000000002563 123.0
HKD2_k127_6712241_28 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000002095 115.0
HKD2_k127_6712241_29 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000004148 112.0
HKD2_k127_6712241_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.501e-202 645.0
HKD2_k127_6712241_30 Belongs to the peptidase S8 family - - - 0.0000000000000000148 96.0
HKD2_k127_6712241_31 transcription initiation from RNA polymerase II promoter - - - 0.00002182 49.0
HKD2_k127_6712241_4 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 616.0
HKD2_k127_6712241_5 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 524.0
HKD2_k127_6712241_6 GTP binding K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 514.0
HKD2_k127_6712241_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 484.0
HKD2_k127_6712241_8 PFAM Isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 444.0
HKD2_k127_6712241_9 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 400.0
HKD2_k127_6721573_0 DNA-directed 5'-3' RNA polymerase activity K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1945.0
HKD2_k127_6721573_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1304.0
HKD2_k127_6721573_10 protein transport K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 9.756e-211 666.0
HKD2_k127_6721573_100 - - - - 0.000000000000000009466 83.0
HKD2_k127_6721573_101 Ribosomal protein L33 K02913 - - 0.00000000000000006007 81.0
HKD2_k127_6721573_102 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000006501 94.0
HKD2_k127_6721573_103 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000004509 93.0
HKD2_k127_6721573_104 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000006051 78.0
HKD2_k127_6721573_105 phosphorelay signal transduction system - - - 0.00000000000001093 80.0
HKD2_k127_6721573_106 histone H1-like protein - - - 0.00000000000002688 74.0
HKD2_k127_6721573_107 Rhodanese Homology Domain - - - 0.00000000000004248 79.0
HKD2_k127_6721573_108 Protein of unknown function (DUF2911) - - - 0.00000000000006599 83.0
HKD2_k127_6721573_109 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000008375 69.0
HKD2_k127_6721573_11 TonB-dependent receptor K02014 - - 1.697e-207 679.0
HKD2_k127_6721573_110 deoxyhypusine monooxygenase activity - - - 0.000000000002064 79.0
HKD2_k127_6721573_111 TIGRFAM TonB family protein K03832 - - 0.000000000003172 79.0
HKD2_k127_6721573_112 Regulatory protein, FmdB family - - - 0.00000000004846 66.0
HKD2_k127_6721573_113 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000004904 66.0
HKD2_k127_6721573_114 Protein of unknown function (DUF1573) - - - 0.0000000002959 70.0
HKD2_k127_6721573_116 peptidyl-tyrosine sulfation - - - 0.00000002956 66.0
HKD2_k127_6721573_117 - - - - 0.0000002326 55.0
HKD2_k127_6721573_119 FeoA K04758 - - 0.000001469 53.0
HKD2_k127_6721573_12 CTP:tRNA cytidylyltransferase activity K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 577.0
HKD2_k127_6721573_122 - - - - 0.0002544 44.0
HKD2_k127_6721573_123 Tetratricopeptide TPR_2 repeat protein - - - 0.000399 53.0
HKD2_k127_6721573_13 protein transport across the cell outer membrane K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 536.0
HKD2_k127_6721573_14 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 510.0
HKD2_k127_6721573_15 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 512.0
HKD2_k127_6721573_16 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 488.0
HKD2_k127_6721573_17 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 474.0
HKD2_k127_6721573_18 lysine biosynthetic process via aminoadipic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 465.0
HKD2_k127_6721573_19 ATP-dependent DNA helicase activity K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 465.0
HKD2_k127_6721573_2 with chaperone activity ATP-binding subunit K03696 - - 0.0 1130.0
HKD2_k127_6721573_20 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000166,GO:0000287,GO:0000820,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006521,GO:0006541,GO:0006542,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0010565,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0019222,GO:0019752,GO:0030554,GO:0031323,GO:0032553,GO:0032555,GO:0032559,GO:0033238,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 458.0
HKD2_k127_6721573_21 RNA polymerase activity K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 420.0
HKD2_k127_6721573_22 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 412.0
HKD2_k127_6721573_23 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 416.0
HKD2_k127_6721573_24 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 416.0
HKD2_k127_6721573_25 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 409.0
HKD2_k127_6721573_26 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 392.0
HKD2_k127_6721573_27 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 390.0
HKD2_k127_6721573_28 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 380.0
HKD2_k127_6721573_29 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 401.0
HKD2_k127_6721573_3 nucleotide-excision repair K03701 - - 0.0 1098.0
HKD2_k127_6721573_30 inositol 2-dehydrogenase activity K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 379.0
HKD2_k127_6721573_31 exonuclease activity K16899 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 402.0
HKD2_k127_6721573_32 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 363.0
HKD2_k127_6721573_33 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 366.0
HKD2_k127_6721573_34 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 345.0
HKD2_k127_6721573_35 4-amino-4-deoxy-L-arabinose transferase activity K13687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 362.0
HKD2_k127_6721573_36 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 326.0
HKD2_k127_6721573_37 rRNA binding K02986 GO:0000028,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006446,GO:0006450,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030371,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031554,GO:0031564,GO:0032268,GO:0032269,GO:0032270,GO:0032991,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045727,GO:0045903,GO:0045947,GO:0048027,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990145,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 323.0
HKD2_k127_6721573_38 regulation of translation K02863 GO:0000027,GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006417,GO:0006446,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045947,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 321.0
HKD2_k127_6721573_39 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 327.0
HKD2_k127_6721573_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0030312,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1084.0
HKD2_k127_6721573_40 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
HKD2_k127_6721573_41 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 306.0
HKD2_k127_6721573_42 protein transport across the cell outer membrane K02666,K12066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001405 281.0
HKD2_k127_6721573_43 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008966 268.0
HKD2_k127_6721573_44 rRNA binding K02988 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 251.0
HKD2_k127_6721573_45 tRNA binding K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000006502 249.0
HKD2_k127_6721573_46 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000002643 233.0
HKD2_k127_6721573_47 tRNA binding K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003044 233.0
HKD2_k127_6721573_48 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.00000000000000000000000000000000000000000000000000000000000000000004243 243.0
HKD2_k127_6721573_49 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000004265 233.0
HKD2_k127_6721573_5 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 6.253e-237 746.0
HKD2_k127_6721573_50 Pilus assembly protein PilX K02673 - - 0.00000000000000000000000000000000000000000000000000000000000000000136 244.0
HKD2_k127_6721573_51 Forms part of the polypeptide exit tunnel K02926,K16193 GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003700,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008428,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030234,GO:0030312,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032069,GO:0032074,GO:0032268,GO:0032269,GO:0032991,GO:0032993,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0065003,GO:0065007,GO:0065009,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0098772,GO:0140110,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000002406 232.0
HKD2_k127_6721573_52 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000452 228.0
HKD2_k127_6721573_53 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000001393 228.0
HKD2_k127_6721573_54 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002406 215.0
HKD2_k127_6721573_55 rRNA binding K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000008399 218.0
HKD2_k127_6721573_56 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000001267 239.0
HKD2_k127_6721573_57 glycolate biosynthetic process K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000001516 220.0
HKD2_k127_6721573_58 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000003071 224.0
HKD2_k127_6721573_59 efflux transmembrane transporter activity K12340 - - 0.00000000000000000000000000000000000000000000000000000000000158 226.0
HKD2_k127_6721573_6 - - - - 3.591e-226 744.0
HKD2_k127_6721573_60 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000005775 209.0
HKD2_k127_6721573_61 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000011 206.0
HKD2_k127_6721573_62 cellulose binding K07279 - - 0.0000000000000000000000000000000000000000000000000000000001319 222.0
HKD2_k127_6721573_63 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000002643 226.0
HKD2_k127_6721573_64 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000007557 201.0
HKD2_k127_6721573_65 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000009552 192.0
HKD2_k127_6721573_66 - - - - 0.00000000000000000000000000000000000000000000000000007142 194.0
HKD2_k127_6721573_67 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000000000000000000000000000000000000000002181 199.0
HKD2_k127_6721573_68 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000008144 175.0
HKD2_k127_6721573_69 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000004543 175.0
HKD2_k127_6721573_7 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0006950,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0010467,GO:0016020,GO:0019538,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0034641,GO:0034645,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071704,GO:0071944,GO:0090087,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 5.775e-224 698.0
HKD2_k127_6721573_70 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000002991 161.0
HKD2_k127_6721573_71 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001726 158.0
HKD2_k127_6721573_72 rRNA binding K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000000000000000000000000000001884 161.0
HKD2_k127_6721573_73 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000003104 159.0
HKD2_k127_6721573_74 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000004212 156.0
HKD2_k127_6721573_75 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001355 158.0
HKD2_k127_6721573_76 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000001608 166.0
HKD2_k127_6721573_77 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000001781 158.0
HKD2_k127_6721573_78 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002451 147.0
HKD2_k127_6721573_79 - K07275 - - 0.00000000000000000000000000000000000004669 152.0
HKD2_k127_6721573_8 ferrous iron transmembrane transporter activity K04759 - - 1.602e-219 705.0
HKD2_k127_6721573_80 - - - - 0.0000000000000000000000000000000000007933 151.0
HKD2_k127_6721573_81 Thioredoxin-like K02199 - - 0.000000000000000000000000000000000001093 146.0
HKD2_k127_6721573_82 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001438 141.0
HKD2_k127_6721573_83 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000002843 141.0
HKD2_k127_6721573_84 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000007967 136.0
HKD2_k127_6721573_85 Ethyl tert-butyl ether degradation - - - 0.0000000000000000000000000000000007236 132.0
HKD2_k127_6721573_86 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000009045 132.0
HKD2_k127_6721573_87 DNA mediated transformation - - - 0.00000000000000000000000000000002448 134.0
HKD2_k127_6721573_88 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000005818 129.0
HKD2_k127_6721573_89 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000002125 130.0
HKD2_k127_6721573_9 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 2.217e-217 691.0
HKD2_k127_6721573_90 rRNA binding K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002837 125.0
HKD2_k127_6721573_91 Pfam:DUF59 K02612 - - 0.00000000000000000000000000001315 121.0
HKD2_k127_6721573_92 - - - - 0.0000000000000000000000000007939 117.0
HKD2_k127_6721573_93 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000005932 123.0
HKD2_k127_6721573_94 rRNA binding K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000059 104.0
HKD2_k127_6721573_95 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000002184 104.0
HKD2_k127_6721573_97 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000005627 91.0
HKD2_k127_6721573_98 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001566 86.0
HKD2_k127_6721573_99 - - - - 0.000000000000000002148 90.0
HKD2_k127_6914997_0 1-deoxy-D-xylulose-5-phosphate synthase activity K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 1.286e-279 871.0
HKD2_k127_6914997_1 aspartate-tRNA(Asn) ligase activity K01876 GO:0003674,GO:0003824,GO:0004812,GO:0004815,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006422,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.12 4.201e-242 761.0
HKD2_k127_6914997_10 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 450.0
HKD2_k127_6914997_11 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 432.0
HKD2_k127_6914997_12 phosphate starvation-inducible protein PhoH K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 422.0
HKD2_k127_6914997_13 smart pdz dhr glgf K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 410.0
HKD2_k127_6914997_14 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 408.0
HKD2_k127_6914997_15 exodeoxyribonuclease VII activity K03601,K03797 - 3.1.11.6,3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 386.0
HKD2_k127_6914997_16 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 369.0
HKD2_k127_6914997_17 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 355.0
HKD2_k127_6914997_18 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 340.0
HKD2_k127_6914997_19 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 334.0
HKD2_k127_6914997_2 COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and K03182 - 4.1.1.98 1.967e-237 747.0
HKD2_k127_6914997_20 3-dehydroquinate dehydratase activity K00014,K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 336.0
HKD2_k127_6914997_21 lipoprotein localization to outer membrane K09808,K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 332.0
HKD2_k127_6914997_22 lipoprotein localization to outer membrane K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 308.0
HKD2_k127_6914997_23 phosphorelay signal transduction system K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000053 286.0
HKD2_k127_6914997_24 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 294.0
HKD2_k127_6914997_25 serine-type endopeptidase activity K09973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 289.0
HKD2_k127_6914997_26 TIGRFAM MazG family protein K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 282.0
HKD2_k127_6914997_27 competence protein COMEC K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005087 301.0
HKD2_k127_6914997_28 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007273 278.0
HKD2_k127_6914997_29 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009227 282.0
HKD2_k127_6914997_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 6.065e-221 696.0
HKD2_k127_6914997_30 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001049 276.0
HKD2_k127_6914997_31 cytochrome complex assembly K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001113 274.0
HKD2_k127_6914997_32 PFAM peptidase S58, DmpA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009109 265.0
HKD2_k127_6914997_33 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
HKD2_k127_6914997_34 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002256 256.0
HKD2_k127_6914997_35 Phosphate sensor histidine kinase, HAMP and PAS domain-containing K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000005124 255.0
HKD2_k127_6914997_36 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006478 249.0
HKD2_k127_6914997_37 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000006522 247.0
HKD2_k127_6914997_38 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000004134 239.0
HKD2_k127_6914997_39 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
HKD2_k127_6914997_4 4-Hydroxyphenylpyruvate dioxygenase - - - 2.179e-207 653.0
HKD2_k127_6914997_40 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000009336 229.0
HKD2_k127_6914997_41 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000009375 247.0
HKD2_k127_6914997_42 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000592 229.0
HKD2_k127_6914997_43 cell envelope organization K05807,K08309 - - 0.0000000000000000000000000000000000000000000000000000000000005533 222.0
HKD2_k127_6914997_44 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000001345 214.0
HKD2_k127_6914997_45 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000001604 227.0
HKD2_k127_6914997_46 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000002615 215.0
HKD2_k127_6914997_47 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000007799 214.0
HKD2_k127_6914997_48 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000002986 206.0
HKD2_k127_6914997_49 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
HKD2_k127_6914997_5 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 7.716e-195 616.0
HKD2_k127_6914997_50 Belongs to the pseudouridine synthase RsuA family K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000006322 196.0
HKD2_k127_6914997_51 acyl-coa hydrolase K01073 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 3.1.2.20 0.000000000000000000000000000000000000000000000000001205 191.0
HKD2_k127_6914997_52 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000002148 198.0
HKD2_k127_6914997_53 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000001213 184.0
HKD2_k127_6914997_54 Prephenate dehydrogenase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000001207 179.0
HKD2_k127_6914997_55 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000002311 173.0
HKD2_k127_6914997_56 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000005179 173.0
HKD2_k127_6914997_57 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000007698 173.0
HKD2_k127_6914997_58 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000003587 182.0
HKD2_k127_6914997_59 - - - - 0.00000000000000000000000000000000000000002327 154.0
HKD2_k127_6914997_6 Cytochrome C-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 560.0
HKD2_k127_6914997_60 ATPase activity K01990,K02193 - 3.6.3.41 0.0000000000000000000000000000000000000001415 161.0
HKD2_k127_6914997_61 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000004897 164.0
HKD2_k127_6914997_62 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000001891 153.0
HKD2_k127_6914997_63 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000009886 143.0
HKD2_k127_6914997_64 positive regulation of growth rate - - - 0.00000000000000000000000000000001752 136.0
HKD2_k127_6914997_65 RDD family - - - 0.00000000000000000000000000000004947 130.0
HKD2_k127_6914997_66 nUDIX hydrolase K01515,K08310 - 3.6.1.13,3.6.1.67 0.00000000000000000000000000000007792 129.0
HKD2_k127_6914997_67 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000001052 139.0
HKD2_k127_6914997_68 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000008732 101.0
HKD2_k127_6914997_69 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000001592 102.0
HKD2_k127_6914997_7 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 503.0
HKD2_k127_6914997_70 PFAM Stress responsive alpha-beta barrel domain protein - - - 0.00000000000000246 81.0
HKD2_k127_6914997_71 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000002195 64.0
HKD2_k127_6914997_73 Membrane - - - 0.0000001014 60.0
HKD2_k127_6914997_76 PFAM WD40-like beta Propeller - - - 0.0001641 53.0
HKD2_k127_6914997_8 translation release factor activity K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 476.0
HKD2_k127_6914997_9 Tryptophanyl-tRNA synthetase K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 473.0
HKD2_k127_6970875_0 DEAD DEAH box helicase K03724 - - 0.0 1105.0
HKD2_k127_6970875_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.742e-291 922.0
HKD2_k127_6970875_10 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 464.0
HKD2_k127_6970875_11 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 465.0
HKD2_k127_6970875_12 ferredoxin-NADP+ reductase activity K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 450.0
HKD2_k127_6970875_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 377.0
HKD2_k127_6970875_14 nitronate monooxygenase activity K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 368.0
HKD2_k127_6970875_15 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 343.0
HKD2_k127_6970875_16 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 331.0
HKD2_k127_6970875_17 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 308.0
HKD2_k127_6970875_18 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001832 283.0
HKD2_k127_6970875_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000004544 261.0
HKD2_k127_6970875_2 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 2.013e-228 722.0
HKD2_k127_6970875_20 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000001274 229.0
HKD2_k127_6970875_21 rRNA processing K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000001078 222.0
HKD2_k127_6970875_22 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000004649 223.0
HKD2_k127_6970875_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001234 195.0
HKD2_k127_6970875_24 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000002319 192.0
HKD2_k127_6970875_25 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000003518 188.0
HKD2_k127_6970875_26 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.0000000000000000000000000000000000000000000000002803 182.0
HKD2_k127_6970875_27 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000009801 169.0
HKD2_k127_6970875_28 Highly conserved protein containing a thioredoxin domain K18581 - 3.2.1.180 0.00000000000000000000000000000000000000000008945 164.0
HKD2_k127_6970875_29 NADH dehydrogenase (ubiquinone) flavoprotein 2 K03943 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0007275,GO:0007399,GO:0007507,GO:0008137,GO:0008150,GO:0008152,GO:0009055,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009888,GO:0009987,GO:0010257,GO:0014706,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0019866,GO:0022607,GO:0022900,GO:0022904,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0032981,GO:0032991,GO:0033108,GO:0034622,GO:0034641,GO:0042773,GO:0042775,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0045333,GO:0046034,GO:0046483,GO:0048513,GO:0048731,GO:0048738,GO:0048856,GO:0050136,GO:0055086,GO:0055114,GO:0060537,GO:0065003,GO:0070469,GO:0071704,GO:0071840,GO:0072359,GO:0072521,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000009504 161.0
HKD2_k127_6970875_3 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 1.246e-217 694.0
HKD2_k127_6970875_30 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000002564 152.0
HKD2_k127_6970875_31 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000005544 149.0
HKD2_k127_6970875_32 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000002585 143.0
HKD2_k127_6970875_33 regulation of translation K03530,K05788 - - 0.0000000000000000000000000000002566 125.0
HKD2_k127_6970875_34 amine dehydrogenase activity - - - 0.000000000000000000000000000002794 133.0
HKD2_k127_6970875_35 gas vesicle protein - - - 0.000000000000000000000000000003321 126.0
HKD2_k127_6970875_36 membrane transporter protein K07090 - - 0.00000000000000000000000000007287 118.0
HKD2_k127_6970875_37 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000006678 123.0
HKD2_k127_6970875_38 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000001407 104.0
HKD2_k127_6970875_39 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000001933 85.0
HKD2_k127_6970875_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 1.156e-207 667.0
HKD2_k127_6970875_40 COG2146 Ferredoxin subunits of nitrite reductase and K00363,K05710 - 1.7.1.15 0.00000000000005417 76.0
HKD2_k127_6970875_42 Tetratricopeptide repeat - - - 0.00000000009605 72.0
HKD2_k127_6970875_43 - - - - 0.00002868 47.0
HKD2_k127_6970875_5 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 587.0
HKD2_k127_6970875_6 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 582.0
HKD2_k127_6970875_7 NAD binding K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 559.0
HKD2_k127_6970875_8 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 529.0
HKD2_k127_6970875_9 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 474.0
HKD2_k127_7268669_0 GXGXG motif K00265 - 1.4.1.13,1.4.1.14 0.0 1647.0
HKD2_k127_7268669_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1295.0
HKD2_k127_7268669_10 secondary active sulfate transmembrane transporter activity K06901 - - 5.834e-220 694.0
HKD2_k127_7268669_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.507e-211 664.0
HKD2_k127_7268669_12 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.785e-209 662.0
HKD2_k127_7268669_13 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 7.783e-209 676.0
HKD2_k127_7268669_14 2-Nitropropane dioxygenase - - - 8.802e-198 634.0
HKD2_k127_7268669_15 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 7.537e-197 626.0
HKD2_k127_7268669_16 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 610.0
HKD2_k127_7268669_17 Sodium:sulfate symporter transmembrane region K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 580.0
HKD2_k127_7268669_18 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 566.0
HKD2_k127_7268669_19 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 544.0
HKD2_k127_7268669_2 Glycosyl hydrolases family 2, TIM barrel domain K01190,K01195 GO:0003674,GO:0003824,GO:0004553,GO:0004565,GO:0005575,GO:0005975,GO:0005984,GO:0005988,GO:0005990,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009341,GO:0009987,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0032991,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575,GO:1902494 3.2.1.23,3.2.1.31 0.0 1122.0
HKD2_k127_7268669_20 L-rhamnose isomerase activity K00848,K01813 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008270,GO:0008740,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0022607,GO:0030145,GO:0030246,GO:0032991,GO:0033296,GO:0036094,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046872,GO:0046914,GO:0048029,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901575 2.7.1.5,5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 526.0
HKD2_k127_7268669_21 FGGY family of carbohydrate kinases, N-terminal domain K00848,K00879 GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 2.7.1.5,2.7.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 521.0
HKD2_k127_7268669_22 PFAM Acetyl xylan esterase K01060 - 3.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 492.0
HKD2_k127_7268669_23 Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 492.0
HKD2_k127_7268669_24 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 476.0
HKD2_k127_7268669_25 Sodium:dicarboxylate symporter family K11102 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 477.0
HKD2_k127_7268669_26 Ketol-acid reductoisomerase K00053 GO:0000002,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004455,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006549,GO:0006551,GO:0006573,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009295,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0042645,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0055114,GO:0070013,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 471.0
HKD2_k127_7268669_27 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 492.0
HKD2_k127_7268669_28 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 469.0
HKD2_k127_7268669_29 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 447.0
HKD2_k127_7268669_3 symporter activity K03307 - - 3.489e-302 932.0
HKD2_k127_7268669_30 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 423.0
HKD2_k127_7268669_31 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 420.0
HKD2_k127_7268669_32 SIS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 419.0
HKD2_k127_7268669_33 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 418.0
HKD2_k127_7268669_34 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 398.0
HKD2_k127_7268669_35 choline dehydrogenase activity - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 403.0
HKD2_k127_7268669_36 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 389.0
HKD2_k127_7268669_37 Glycerophosphoryl diester phosphodiesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 383.0
HKD2_k127_7268669_38 Mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 365.0
HKD2_k127_7268669_39 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 340.0
HKD2_k127_7268669_4 alpha-L-rhamnosidase - - - 1.157e-295 940.0
HKD2_k127_7268669_40 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 341.0
HKD2_k127_7268669_41 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 344.0
HKD2_k127_7268669_42 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 331.0
HKD2_k127_7268669_43 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 333.0
HKD2_k127_7268669_44 Zinc metalloprotease (Elastase) K20274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 353.0
HKD2_k127_7268669_45 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 329.0
HKD2_k127_7268669_46 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 311.0
HKD2_k127_7268669_47 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 287.0
HKD2_k127_7268669_48 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002541 276.0
HKD2_k127_7268669_49 monoamine oxidase activity K06955 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050664,GO:0051287,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002282 271.0
HKD2_k127_7268669_5 iron-nicotianamine transmembrane transporter activity - - - 7.267e-277 872.0
HKD2_k127_7268669_50 Belongs to the glycosyl hydrolase family 6 K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000182 276.0
HKD2_k127_7268669_51 spore germination K03298 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004738 248.0
HKD2_k127_7268669_52 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000001269 240.0
HKD2_k127_7268669_53 guanyl-nucleotide exchange factor activity K01191,K01406,K20276 - 3.2.1.24,3.4.24.40 0.000000000000000000000000000000000000000000000000000000000001307 241.0
HKD2_k127_7268669_54 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000000000000000000741 208.0
HKD2_k127_7268669_55 Surface antigen - - - 0.00000000000000000000000000000000000000000000000000000001322 213.0
HKD2_k127_7268669_56 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000105 199.0
HKD2_k127_7268669_57 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000007524 201.0
HKD2_k127_7268669_58 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000001176 198.0
HKD2_k127_7268669_59 PFAM Major Facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000002903 203.0
HKD2_k127_7268669_6 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.107e-276 861.0
HKD2_k127_7268669_60 - - - - 0.00000000000000000000000000000000000000000000000000003219 209.0
HKD2_k127_7268669_61 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000000000000002683 196.0
HKD2_k127_7268669_62 PFAM FecR protein K20276 - - 0.000000000000000000000000000000000000000000000008962 199.0
HKD2_k127_7268669_63 TPR repeat - - - 0.000000000000000000000000000000000000000000008993 176.0
HKD2_k127_7268669_64 - - - - 0.0000000000000000000000000000000000000000001229 169.0
HKD2_k127_7268669_66 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000004029 141.0
HKD2_k127_7268669_67 - - - - 0.000000000000000000000000000000000005473 147.0
HKD2_k127_7268669_68 - - - - 0.00000000000000000000000000000001079 134.0
HKD2_k127_7268669_69 - - - - 0.00000000000000000000000000000001971 129.0
HKD2_k127_7268669_7 Right handed beta helix region - - - 9.698e-257 811.0
HKD2_k127_7268669_70 FHA domain K07315 - 3.1.3.3 0.00000000000000000000000000000006191 138.0
HKD2_k127_7268669_71 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000006932 129.0
HKD2_k127_7268669_72 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000001411 142.0
HKD2_k127_7268669_73 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000003368 127.0
HKD2_k127_7268669_74 Heparinase II/III-like protein - - - 0.00000000000000000000000000391 130.0
HKD2_k127_7268669_75 glucan 1,4-alpha-glucosidase activity K05989,K20541 - 3.2.1.40 0.0000000000000000000000001949 124.0
HKD2_k127_7268669_76 -acetyltransferase - - - 0.0000000000000000000001271 104.0
HKD2_k127_7268669_77 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.0000000000000000003035 100.0
HKD2_k127_7268669_78 cellulose binding K01179,K21449 - 3.2.1.4 0.00000000000000006618 97.0
HKD2_k127_7268669_79 Hexapeptide repeat of succinyl-transferase - - - 0.0000000003177 70.0
HKD2_k127_7268669_8 - - - - 1.046e-226 726.0
HKD2_k127_7268669_80 - - - - 0.0000000004347 63.0
HKD2_k127_7268669_81 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000001408 61.0
HKD2_k127_7268669_82 O-Antigen ligase K16705 - - 0.0000004441 62.0
HKD2_k127_7268669_83 PFAM glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.0000008128 64.0
HKD2_k127_7268669_84 - - - - 0.000005968 55.0
HKD2_k127_7268669_85 Outer membrane lipoprotein Blc K03098 - - 0.0001484 47.0
HKD2_k127_7268669_9 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.988e-221 704.0
HKD2_k127_7395576_0 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0 4130.0
HKD2_k127_7395576_1 COGs COG1020 Non-ribosomal peptide synthetase modules and related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 377.0
HKD2_k127_7724773_0 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 546.0
HKD2_k127_7724773_1 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 521.0
HKD2_k127_7724773_10 transferase activity, transferring glycosyl groups K00721,K03820 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 330.0
HKD2_k127_7724773_11 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 324.0
HKD2_k127_7724773_12 quinolinate catabolic process K00278,K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 300.0
HKD2_k127_7724773_13 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006426 280.0
HKD2_k127_7724773_14 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001997 272.0
HKD2_k127_7724773_15 translation release factor activity K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006208 248.0
HKD2_k127_7724773_16 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001719 259.0
HKD2_k127_7724773_17 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001014 247.0
HKD2_k127_7724773_18 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000006178 207.0
HKD2_k127_7724773_19 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000001258 147.0
HKD2_k127_7724773_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 491.0
HKD2_k127_7724773_20 Thioesterase K07107 - - 0.0000000000000000000000000000000005689 135.0
HKD2_k127_7724773_21 Trm112p-like protein K09791 - - 0.000000000005754 71.0
HKD2_k127_7724773_3 undecaprenyl-phosphate glucose phosphotransferase activity K05946,K21303 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.7.8.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007978 490.0
HKD2_k127_7724773_4 malonyl-CoA biosynthetic process K01962,K01963 GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 479.0
HKD2_k127_7724773_5 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 417.0
HKD2_k127_7724773_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 399.0
HKD2_k127_7724773_7 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 366.0
HKD2_k127_7724773_8 extracellular polysaccharide biosynthetic process K07011,K16554,K20998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 362.0
HKD2_k127_7724773_9 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 343.0
HKD2_k127_7742100_0 protein conserved in bacteria K09955 - - 3.426e-270 854.0
HKD2_k127_7742100_1 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 5.511e-254 813.0
HKD2_k127_7742100_10 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 590.0
HKD2_k127_7742100_11 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 512.0
HKD2_k127_7742100_12 argininosuccinate lyase activity K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 485.0
HKD2_k127_7742100_13 phosphorelay signal transduction system K07713,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 464.0
HKD2_k127_7742100_14 PFAM Alcohol dehydrogenase GroES domain protein K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 451.0
HKD2_k127_7742100_15 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 452.0
HKD2_k127_7742100_16 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 428.0
HKD2_k127_7742100_17 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 420.0
HKD2_k127_7742100_18 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 421.0
HKD2_k127_7742100_19 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 415.0
HKD2_k127_7742100_2 ATP-dependent helicase K03579 - 3.6.4.13 3.737e-252 805.0
HKD2_k127_7742100_20 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 406.0
HKD2_k127_7742100_21 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 391.0
HKD2_k127_7742100_22 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 386.0
HKD2_k127_7742100_23 Domain of unknown function (DUF4153) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 402.0
HKD2_k127_7742100_24 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 382.0
HKD2_k127_7742100_25 Aminotransferase class-III K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 365.0
HKD2_k127_7742100_26 beta-glucosidase activity K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 357.0
HKD2_k127_7742100_27 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 345.0
HKD2_k127_7742100_28 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 347.0
HKD2_k127_7742100_29 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 323.0
HKD2_k127_7742100_3 Belongs to the ribulokinase family K00853 - 2.7.1.16 4.134e-240 759.0
HKD2_k127_7742100_30 PFAM Class II Aldolase and Adducin N-terminal domain K03077 - 5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 314.0
HKD2_k127_7742100_31 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 337.0
HKD2_k127_7742100_32 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 310.0
HKD2_k127_7742100_33 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 306.0
HKD2_k127_7742100_35 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007246 294.0
HKD2_k127_7742100_36 PFAM Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001756 264.0
HKD2_k127_7742100_37 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000098 250.0
HKD2_k127_7742100_38 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005804 241.0
HKD2_k127_7742100_39 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000007382 256.0
HKD2_k127_7742100_4 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 9.058e-230 720.0
HKD2_k127_7742100_40 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000003323 203.0
HKD2_k127_7742100_41 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000006944 201.0
HKD2_k127_7742100_42 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000003331 201.0
HKD2_k127_7742100_43 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000002886 202.0
HKD2_k127_7742100_44 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000001851 191.0
HKD2_k127_7742100_45 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000002898 176.0
HKD2_k127_7742100_46 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000004339 147.0
HKD2_k127_7742100_47 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000008439 138.0
HKD2_k127_7742100_48 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000000008806 138.0
HKD2_k127_7742100_49 cellulose binding - - - 0.0000000000000000000000000000000007172 147.0
HKD2_k127_7742100_5 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 7.594e-200 629.0
HKD2_k127_7742100_50 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000005989 126.0
HKD2_k127_7742100_51 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000007682 124.0
HKD2_k127_7742100_52 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000002496 116.0
HKD2_k127_7742100_53 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.00000000000000000003962 106.0
HKD2_k127_7742100_55 - - - - 0.0000000000002439 77.0
HKD2_k127_7742100_56 amine dehydrogenase activity - - - 0.0000000001863 72.0
HKD2_k127_7742100_57 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00007101 55.0
HKD2_k127_7742100_6 Beta-L-arabinofuranosidase, GH127 K09955 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 613.0
HKD2_k127_7742100_7 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 633.0
HKD2_k127_7742100_8 argininosuccinate synthase activity K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 577.0
HKD2_k127_7742100_9 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 573.0
HKD2_k127_8088525_0 synthase K13611,K16416 - - 2.599e-200 644.0
HKD2_k127_8324684_0 Uncharacterized protein family (UPF0051) K09014 - - 5.779e-262 812.0
HKD2_k127_8324684_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 590.0
HKD2_k127_8324684_10 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000000002924 188.0
HKD2_k127_8324684_11 protein maturation K13628 - - 0.000000000000000000000000000000000000000001009 160.0
HKD2_k127_8324684_12 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000001618 149.0
HKD2_k127_8324684_13 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000000000000000000000000000001647 139.0
HKD2_k127_8324684_14 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000001551 133.0
HKD2_k127_8324684_16 Iron-sulphur cluster assembly - - - 0.0000000000003039 74.0
HKD2_k127_8324684_17 - - - - 0.000009213 52.0
HKD2_k127_8324684_18 - - - - 0.00001595 48.0
HKD2_k127_8324684_2 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 417.0
HKD2_k127_8324684_3 ATPase activity K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 402.0
HKD2_k127_8324684_4 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 402.0
HKD2_k127_8324684_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 297.0
HKD2_k127_8324684_6 cAMP biosynthetic process K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004127 283.0
HKD2_k127_8324684_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 276.0
HKD2_k127_8324684_8 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000807 218.0
HKD2_k127_8324684_9 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009268,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010269,GO:0010447,GO:0016020,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0020012,GO:0030145,GO:0030682,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0042597,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052059,GO:0052173,GO:0052200,GO:0052385,GO:0052550,GO:0052564,GO:0052567,GO:0052572,GO:0055114,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071291,GO:0071450,GO:0071451,GO:0071944,GO:0072593,GO:0075136,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000999 200.0
HKD2_k127_8452228_0 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 3.485e-277 873.0
HKD2_k127_8452228_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004969 496.0
HKD2_k127_8452228_10 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000004426 179.0
HKD2_k127_8452228_11 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000008931 172.0
HKD2_k127_8452228_12 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000002336 173.0
HKD2_k127_8452228_13 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000002672 158.0
HKD2_k127_8452228_14 Chalcone isomerase-like - - - 0.000000000000000000000000000000000143 151.0
HKD2_k127_8452228_15 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000001175 132.0
HKD2_k127_8452228_16 metallopeptidase activity - - - 0.000000000000000000000000006299 121.0
HKD2_k127_8452228_17 - - - - 0.000000000000003072 88.0
HKD2_k127_8452228_18 PFAM oxidoreductase domain protein - - - 0.0000000000001598 71.0
HKD2_k127_8452228_19 - - - - 0.000001061 57.0
HKD2_k127_8452228_2 PFAM amino acid permease-associated region K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 418.0
HKD2_k127_8452228_20 - - - - 0.000001891 58.0
HKD2_k127_8452228_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 367.0
HKD2_k127_8452228_4 formate dehydrogenase K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 327.0
HKD2_k127_8452228_5 PFAM Xylose - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002746 263.0
HKD2_k127_8452228_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003797 264.0
HKD2_k127_8452228_7 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000006627 239.0
HKD2_k127_8452228_8 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000008067 221.0
HKD2_k127_8452228_9 ApbE family - - - 0.0000000000000000000000000000000000000000000000001071 188.0
HKD2_k127_8849491_0 Polyketide synthase dehydratase - - - 0.0 1973.0
HKD2_k127_8849491_1 Response regulator, receiver K01007 - 2.7.9.2 0.0 1362.0
HKD2_k127_8849491_10 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 561.0
HKD2_k127_8849491_11 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 559.0
HKD2_k127_8849491_12 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 550.0
HKD2_k127_8849491_13 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 530.0
HKD2_k127_8849491_14 transcription antitermination K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 514.0
HKD2_k127_8849491_15 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 492.0
HKD2_k127_8849491_16 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 478.0
HKD2_k127_8849491_17 AMP-binding enzyme C-terminal domain K01897,K02182,K22133 - 6.2.1.3,6.2.1.48,6.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 482.0
HKD2_k127_8849491_18 cyclopropane-fatty-acyl-phospholipid synthase K00574,K18827 - 2.1.1.294,2.1.1.79,2.7.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 475.0
HKD2_k127_8849491_19 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 467.0
HKD2_k127_8849491_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1313.0
HKD2_k127_8849491_20 phosphorelay signal transduction system K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 467.0
HKD2_k127_8849491_21 4 iron, 4 sulfur cluster binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 430.0
HKD2_k127_8849491_22 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 422.0
HKD2_k127_8849491_23 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 415.0
HKD2_k127_8849491_24 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 417.0
HKD2_k127_8849491_25 Belongs to the glycosyl hydrolase 43 family K01278,K03561,K12287 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 434.0
HKD2_k127_8849491_26 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 410.0
HKD2_k127_8849491_27 nicotinamide-nucleotide amidase activity K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 402.0
HKD2_k127_8849491_28 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 398.0
HKD2_k127_8849491_29 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 393.0
HKD2_k127_8849491_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.187e-317 982.0
HKD2_k127_8849491_30 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 389.0
HKD2_k127_8849491_31 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 383.0
HKD2_k127_8849491_32 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 377.0
HKD2_k127_8849491_33 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 364.0
HKD2_k127_8849491_34 Thiolase, N-terminal domain K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 359.0
HKD2_k127_8849491_35 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 317.0
HKD2_k127_8849491_36 heat shock protein binding - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 313.0
HKD2_k127_8849491_37 Fibronectin type 3 domain K01179,K01361,K01637,K01729,K09942,K20276 - 3.2.1.4,3.4.21.96,4.1.3.1,4.2.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 315.0
HKD2_k127_8849491_38 response to copper ion K07156 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007857 297.0
HKD2_k127_8849491_39 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006502 285.0
HKD2_k127_8849491_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.863e-305 960.0
HKD2_k127_8849491_40 Belongs to the glycosyl hydrolase family 6 K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003235 291.0
HKD2_k127_8849491_41 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 271.0
HKD2_k127_8849491_42 Cell division ATP-binding protein ftsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000297 267.0
HKD2_k127_8849491_43 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003173 290.0
HKD2_k127_8849491_44 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001982 259.0
HKD2_k127_8849491_45 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007318 261.0
HKD2_k127_8849491_46 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001092 259.0
HKD2_k127_8849491_47 phosphorelay signal transduction system K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004092 247.0
HKD2_k127_8849491_48 DeoC/LacD family aldolase K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000001154 243.0
HKD2_k127_8849491_49 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 254.0
HKD2_k127_8849491_5 Peptidase, M16 K07263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.219e-268 860.0
HKD2_k127_8849491_50 Belongs to the glycosyl hydrolase 43 family K01181,K09955 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000004199 259.0
HKD2_k127_8849491_51 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000001156 237.0
HKD2_k127_8849491_52 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000005734 221.0
HKD2_k127_8849491_53 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000007616 215.0
HKD2_k127_8849491_54 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000001323 224.0
HKD2_k127_8849491_55 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000001465 232.0
HKD2_k127_8849491_56 SMART Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000001571 217.0
HKD2_k127_8849491_57 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000008119 201.0
HKD2_k127_8849491_58 rRNA binding K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000005263 188.0
HKD2_k127_8849491_59 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000908 180.0
HKD2_k127_8849491_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 5.348e-266 831.0
HKD2_k127_8849491_60 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000006644 187.0
HKD2_k127_8849491_61 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000007029 182.0
HKD2_k127_8849491_62 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002406 172.0
HKD2_k127_8849491_63 Polysaccharide biosynthesis protein K03328,K16695 - - 0.000000000000000000000000000000000000000000006966 181.0
HKD2_k127_8849491_64 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000008659 171.0
HKD2_k127_8849491_65 alpha beta - - - 0.0000000000000000000000000000000000000000004219 171.0
HKD2_k127_8849491_66 Peptidase M56 - - - 0.00000000000000000000000000000000000000002521 169.0
HKD2_k127_8849491_67 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000007117 160.0
HKD2_k127_8849491_68 Belongs to the glycosyl hydrolase 13 family - - - 0.000000000000000000000000000000000000002742 170.0
HKD2_k127_8849491_69 biotin transmembrane transporter activity K03523 - - 0.0000000000000000000000000000000000000216 151.0
HKD2_k127_8849491_7 glutamate dehydrogenase [NAD(P)+] activity K00262 - 1.4.1.4 4.466e-249 776.0
HKD2_k127_8849491_70 PFAM peptidylprolyl isomerase FKBP-type K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000001756 146.0
HKD2_k127_8849491_71 PFAM Uncharacterised BCR, COG1649 K01186,K01197,K05988,K11931,K18197 - 3.2.1.11,3.2.1.18,3.2.1.35,4.2.2.23 0.000000000000000000000000000000000006649 157.0
HKD2_k127_8849491_72 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000005881 138.0
HKD2_k127_8849491_73 - - - - 0.000000000000000000000000000000005099 134.0
HKD2_k127_8849491_74 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000003424 133.0
HKD2_k127_8849491_75 Binds the 23S rRNA K02909 GO:0008150,GO:0040007 - 0.0000000000000000000000000001866 116.0
HKD2_k127_8849491_76 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000002986 126.0
HKD2_k127_8849491_77 - - - - 0.000000000000000000000000002341 116.0
HKD2_k127_8849491_78 Glycosyltransferase like family 2 - - - 0.000000000000000000000000003666 122.0
HKD2_k127_8849491_79 - - - - 0.00000000000000000000000001546 115.0
HKD2_k127_8849491_8 Histidine kinase K02482 - 2.7.13.3 4.275e-227 719.0
HKD2_k127_8849491_80 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001253 108.0
HKD2_k127_8849491_81 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000001275 119.0
HKD2_k127_8849491_82 PFAM phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000000163 117.0
HKD2_k127_8849491_83 pectinesterase activity K10297,K15923,K18197 - 3.2.1.51,4.2.2.23 0.000000000000000000000007207 119.0
HKD2_k127_8849491_84 Modulates RecA activity K03565 - - 0.0000000000000000000002703 104.0
HKD2_k127_8849491_85 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000004683 93.0
HKD2_k127_8849491_86 iron-sulfur cluster assembly - - - 0.00000000000000000003779 92.0
HKD2_k127_8849491_87 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000193 94.0
HKD2_k127_8849491_88 DNA recombination K03546,K03631 - - 0.0000000000000000006385 100.0
HKD2_k127_8849491_89 Protein conserved in bacteria K20276 - - 0.0000000000000000008533 103.0
HKD2_k127_8849491_9 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 6.471e-208 654.0
HKD2_k127_8849491_90 4'-phosphopantetheinyl transferase superfamily - - - 0.00000000000000004372 90.0
HKD2_k127_8849491_92 response regulator - - - 0.000000003464 64.0
HKD2_k127_8849491_93 Sporulation related domain - - - 0.00000003359 62.0
HKD2_k127_9026364_0 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 527.0
HKD2_k127_9026364_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006780,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046394,GO:0046483,GO:0046501,GO:0046502,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 425.0
HKD2_k127_9026364_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 304.0
HKD2_k127_9026364_11 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 302.0
HKD2_k127_9026364_12 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001332 250.0
HKD2_k127_9026364_13 Two component regulator propeller K17763 - - 0.00000000000000000000000000000000000000000000004588 184.0
HKD2_k127_9026364_14 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000003584 171.0
HKD2_k127_9026364_15 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000001161 153.0
HKD2_k127_9026364_16 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000006901 158.0
HKD2_k127_9026364_17 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000006437 117.0
HKD2_k127_9026364_18 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000006797 93.0
HKD2_k127_9026364_19 Cysteine-rich CPXCG - - - 0.000000000002571 70.0
HKD2_k127_9026364_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 407.0
HKD2_k127_9026364_20 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000002077 66.0
HKD2_k127_9026364_22 Protein of unknown function (DUF2892) - - - 0.00000000108 63.0
HKD2_k127_9026364_23 Protein of unknown function with HXXEE motif - - - 0.000004213 55.0
HKD2_k127_9026364_3 glutamyl-tRNA reductase activity K02407,K02492 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 402.0
HKD2_k127_9026364_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 396.0
HKD2_k127_9026364_5 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 392.0
HKD2_k127_9026364_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 348.0
HKD2_k127_9026364_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 336.0
HKD2_k127_9026364_8 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 325.0
HKD2_k127_9026364_9 ferrochelatase activity K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0050896,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 316.0
HKD2_k127_9082189_0 COG COG0383 Alpha-mannosidase - - - 1.316e-285 914.0
HKD2_k127_9082189_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.409e-220 689.0
HKD2_k127_9082189_10 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 385.0
HKD2_k127_9082189_11 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 309.0
HKD2_k127_9082189_12 Fe-S protein K07140 GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009636,GO:0009987,GO:0019748,GO:0042221,GO:0044237,GO:0044248,GO:0050896,GO:0098754 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004063 276.0
HKD2_k127_9082189_13 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000373 206.0
HKD2_k127_9082189_14 - - - - 0.000000000000000000000000000000003748 136.0
HKD2_k127_9082189_15 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000003279 112.0
HKD2_k127_9082189_17 Encoded by K18626 - - 0.00000000000007791 84.0
HKD2_k127_9082189_18 - - - - 0.0000002447 61.0
HKD2_k127_9082189_2 Chitobiase/beta-hexosaminidase C-terminal domain K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 598.0
HKD2_k127_9082189_3 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 591.0
HKD2_k127_9082189_4 PFAM Glycoside hydrolase, family 29 K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 575.0
HKD2_k127_9082189_5 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 481.0
HKD2_k127_9082189_6 Peptidase m28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 483.0
HKD2_k127_9082189_7 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 437.0
HKD2_k127_9082189_8 Belongs to the glycosyl hydrolase 3 family K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 413.0
HKD2_k127_9082189_9 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 397.0
HKD2_k127_9157227_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1729.0
HKD2_k127_9157227_1 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0 1493.0
HKD2_k127_9157227_10 Oligopeptidase F K08602 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 617.0
HKD2_k127_9157227_11 unfolded protein binding K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
HKD2_k127_9157227_12 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 591.0
HKD2_k127_9157227_13 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 530.0
HKD2_k127_9157227_14 PFAM AAA ATPase central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 519.0
HKD2_k127_9157227_15 PFAM beta-lactamase domain protein K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 505.0
HKD2_k127_9157227_16 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 476.0
HKD2_k127_9157227_17 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 460.0
HKD2_k127_9157227_18 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 466.0
HKD2_k127_9157227_19 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 447.0
HKD2_k127_9157227_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.384e-273 868.0
HKD2_k127_9157227_20 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 447.0
HKD2_k127_9157227_21 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 439.0
HKD2_k127_9157227_22 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 439.0
HKD2_k127_9157227_23 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 422.0
HKD2_k127_9157227_24 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 410.0
HKD2_k127_9157227_25 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 402.0
HKD2_k127_9157227_26 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 394.0
HKD2_k127_9157227_27 diaminopimelate decarboxylase activity K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 392.0
HKD2_k127_9157227_28 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 383.0
HKD2_k127_9157227_29 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 383.0
HKD2_k127_9157227_3 amine dehydrogenase activity - - - 1.796e-234 759.0
HKD2_k127_9157227_30 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 366.0
HKD2_k127_9157227_31 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 376.0
HKD2_k127_9157227_32 phosphoserine phosphatase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 363.0
HKD2_k127_9157227_33 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K02805 GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005975,GO:0005976,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009246,GO:0009987,GO:0016051,GO:0016740,GO:0016769,GO:0019180,GO:0019842,GO:0030170,GO:0033692,GO:0034637,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046378,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901576 2.6.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 354.0
HKD2_k127_9157227_34 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 364.0
HKD2_k127_9157227_35 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 346.0
HKD2_k127_9157227_36 iron ion homeostasis K03322,K03709,K04758 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 329.0
HKD2_k127_9157227_37 Belongs to the 'phage' integrase family K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 327.0
HKD2_k127_9157227_38 PhoQ Sensor K01768,K04769,K10914 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 314.0
HKD2_k127_9157227_39 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 297.0
HKD2_k127_9157227_4 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 3.196e-218 682.0
HKD2_k127_9157227_40 - K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001702 267.0
HKD2_k127_9157227_41 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005496 266.0
HKD2_k127_9157227_42 - K01992,K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000001537 244.0
HKD2_k127_9157227_43 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002601 250.0
HKD2_k127_9157227_44 Belongs to the pseudouridine synthase RsuA family K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000003173 220.0
HKD2_k127_9157227_45 PFAM helix-hairpin-helix motif K03575 - - 0.0000000000000000000000000000000000000000000000000000000000008981 223.0
HKD2_k127_9157227_46 - - - - 0.0000000000000000000000000000000000000000000000000000000001245 226.0
HKD2_k127_9157227_47 Pilus assembly protein PilX K02673 - - 0.000000000000000000000000000000000000000000000000000000002613 216.0
HKD2_k127_9157227_48 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000002505 201.0
HKD2_k127_9157227_49 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000013 209.0
HKD2_k127_9157227_5 FeoA - - - 1.439e-215 681.0
HKD2_k127_9157227_50 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000004547 197.0
HKD2_k127_9157227_51 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000008733 201.0
HKD2_k127_9157227_52 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000000000000008 194.0
HKD2_k127_9157227_53 Iron dependent repressor, metal binding and dimerisation domain K03709 - - 0.00000000000000000000000000000000000000000000000004389 188.0
HKD2_k127_9157227_54 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000000000004896 175.0
HKD2_k127_9157227_55 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000001243 172.0
HKD2_k127_9157227_57 metallopeptidase activity K06402 - - 0.0000000000000000000000000000000000000009004 158.0
HKD2_k127_9157227_58 dihydrofolate reductase activity K00287,K18589 - 1.5.1.3 0.00000000000000000000000000000000000001146 149.0
HKD2_k127_9157227_59 Protease prsW family - - - 0.00000000000000000000000000000000000002415 156.0
HKD2_k127_9157227_6 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 3.738e-214 681.0
HKD2_k127_9157227_60 - - - - 0.000000000000000000000000000000000001786 152.0
HKD2_k127_9157227_61 Psort location Cytoplasmic, score 8.96 K03653 - 4.2.99.18 0.000000000000000000000000000000000007848 145.0
HKD2_k127_9157227_62 cell septum assembly - - - 0.00000000000000000000000000000000005098 145.0
HKD2_k127_9157227_63 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000001021 146.0
HKD2_k127_9157227_64 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000001144 129.0
HKD2_k127_9157227_65 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000001508 141.0
HKD2_k127_9157227_66 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000009868 138.0
HKD2_k127_9157227_67 histidine kinase A domain protein - - - 0.0000000000000000000000000000001783 143.0
HKD2_k127_9157227_68 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000004708 123.0
HKD2_k127_9157227_69 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000001626 120.0
HKD2_k127_9157227_7 Aspartate ammonia-lyase K01744 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 6.112e-214 674.0
HKD2_k127_9157227_70 CoA binding domain - - - 0.000000000000000000000000001651 117.0
HKD2_k127_9157227_71 sigma factor antagonist activity K04757,K06379,K08282 - 2.7.11.1 0.000000000000000000000000005049 115.0
HKD2_k127_9157227_72 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000002226 109.0
HKD2_k127_9157227_73 - - - - 0.0000000000000000000001053 105.0
HKD2_k127_9157227_74 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000000000000000001539 113.0
HKD2_k127_9157227_76 Peptidase, M16 K07263 - - 0.00000000000000000001176 94.0
HKD2_k127_9157227_78 Predicted membrane protein (DUF2085) - - - 0.0000000000000000006507 94.0
HKD2_k127_9157227_8 lipopolysaccharide transport - - - 2.186e-213 692.0
HKD2_k127_9157227_80 ABC-2 family transporter protein K01992 - - 0.00000000000000001533 94.0
HKD2_k127_9157227_81 - - - - 0.00000000000001214 85.0
HKD2_k127_9157227_82 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000009099 80.0
HKD2_k127_9157227_83 Planctomycete cytochrome C - - - 0.0000000000006652 74.0
HKD2_k127_9157227_84 - - - - 0.000000000002023 79.0
HKD2_k127_9157227_87 - - - - 0.0000000003156 68.0
HKD2_k127_9157227_88 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000001568 56.0
HKD2_k127_9157227_89 antisigma factor binding K04749 - - 0.0000004941 56.0
HKD2_k127_9157227_9 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.027e-209 666.0
HKD2_k127_9157227_90 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.00000114 54.0
HKD2_k127_9157227_91 heme oxygenase (decyclizing) activity K21481 - 1.14.99.57 0.000001168 59.0
HKD2_k127_9157227_94 cell cycle K05589,K12065,K13052 - - 0.0008962 48.0
HKD2_k127_9444228_0 protein targeting K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1280.0
HKD2_k127_9444228_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.474e-258 810.0
HKD2_k127_9444228_10 lipoprotein localization to outer membrane K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 347.0
HKD2_k127_9444228_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 339.0
HKD2_k127_9444228_12 enoyl-[acyl-carrier-protein] reductase (NADH) activity K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 336.0
HKD2_k127_9444228_13 lipoprotein localization to outer membrane K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 338.0
HKD2_k127_9444228_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 324.0
HKD2_k127_9444228_15 lipoprotein transporter activity K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 311.0
HKD2_k127_9444228_16 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 325.0
HKD2_k127_9444228_17 Peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 308.0
HKD2_k127_9444228_18 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 303.0
HKD2_k127_9444228_19 ATPases associated with a variety of cellular activities K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005762 285.0
HKD2_k127_9444228_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 7.29e-213 679.0
HKD2_k127_9444228_20 cellulase activity K06882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003693 265.0
HKD2_k127_9444228_21 uracil phosphoribosyltransferase activity K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000001111 234.0
HKD2_k127_9444228_22 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.00000000000000000000000000000000000000000000000000000000000001564 226.0
HKD2_k127_9444228_23 spore germination K07790 - - 0.000000000000000000000000000000000000000000000000000000000005696 219.0
HKD2_k127_9444228_24 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000002411 213.0
HKD2_k127_9444228_25 protein methyltransferase activity K02687 - - 0.00000000000000000000000000000000000000000000000000000001855 207.0
HKD2_k127_9444228_26 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000006034 211.0
HKD2_k127_9444228_27 nUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000003212 199.0
HKD2_k127_9444228_28 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000004224 204.0
HKD2_k127_9444228_29 Putative adhesin - - - 0.0000000000000000000000000000000000000000000000001318 188.0
HKD2_k127_9444228_3 acyl-CoA dehydrogenase activity K06446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 589.0
HKD2_k127_9444228_30 Belongs to the P(II) protein family K04751 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006808,GO:0008144,GO:0008150,GO:0009889,GO:0010565,GO:0017076,GO:0019216,GO:0019217,GO:0019222,GO:0030234,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042304,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0046890,GO:0050789,GO:0050790,GO:0050794,GO:0062012,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:0097367,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000001535 179.0
HKD2_k127_9444228_31 Cobalt transport protein K02008 - - 0.00000000000000000000000000009119 127.0
HKD2_k127_9444228_32 metallopeptidase activity K07407 - 3.2.1.22 0.000000000000000000000000005028 121.0
HKD2_k127_9444228_33 Protein conserved in bacteria - - - 0.0000000000000000000001901 112.0
HKD2_k127_9444228_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 490.0
HKD2_k127_9444228_5 homocysteine catabolic process K01372,K02316 - 3.4.22.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 480.0
HKD2_k127_9444228_6 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 439.0
HKD2_k127_9444228_7 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 455.0
HKD2_k127_9444228_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 401.0
HKD2_k127_9444228_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 413.0
HKD2_k127_9531807_0 - - - - 0.0 1684.0
HKD2_k127_9531807_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1306.0
HKD2_k127_9531807_10 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 3.463e-241 760.0
HKD2_k127_9531807_100 ferric iron binding K02217,K22336 GO:0001666,GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009987,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0030312,GO:0033212,GO:0033214,GO:0036293,GO:0042592,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051235,GO:0051238,GO:0051409,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070482,GO:0071944,GO:0097577,GO:0098771 1.16.3.1,1.16.3.2 0.000000000000000000000000000000000000000000000000000007296 195.0
HKD2_k127_9531807_101 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000008875 196.0
HKD2_k127_9531807_102 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000001634 188.0
HKD2_k127_9531807_103 Ser-tRNA(Ala) hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000005663 188.0
HKD2_k127_9531807_104 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000104 201.0
HKD2_k127_9531807_105 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000008798 184.0
HKD2_k127_9531807_106 Histidine kinase - - - 0.000000000000000000000000000000000000000000000004937 198.0
HKD2_k127_9531807_107 Uncharacterized ACR, COG1993 K06199,K09137 - - 0.00000000000000000000000000000000000000000000001359 172.0
HKD2_k127_9531807_108 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000002268 180.0
HKD2_k127_9531807_109 isoprenoid biosynthetic process K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000001916 173.0
HKD2_k127_9531807_11 Pfam L-fucose isomerase, C-terminal domain - - - 7.856e-241 754.0
HKD2_k127_9531807_110 PFAM GCN5-related N-acetyltransferase K03824 - - 0.00000000000000000000000000000000000000000002138 168.0
HKD2_k127_9531807_111 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000004011 167.0
HKD2_k127_9531807_112 BMC - - - 0.00000000000000000000000000000000000000000004391 167.0
HKD2_k127_9531807_113 ethanolamine catabolic process K04027,K08696,K08700 - - 0.00000000000000000000000000000000000000007233 152.0
HKD2_k127_9531807_114 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000000003317 151.0
HKD2_k127_9531807_115 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.00000000000000000000000000000000000001866 146.0
HKD2_k127_9531807_116 - - - - 0.000000000000000000000000000000000001041 144.0
HKD2_k127_9531807_117 ethanolamine catabolic process - - - 0.000000000000000000000000000000000004379 139.0
HKD2_k127_9531807_118 carbohydrate transport K02027 - - 0.000000000000000000000000000000000007592 152.0
HKD2_k127_9531807_119 DeoR C terminal sensor domain K02081 - - 0.00000000000000000000000000000000006676 143.0
HKD2_k127_9531807_12 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.521e-237 743.0
HKD2_k127_9531807_120 GYD domain - - - 0.0000000000000000000000000000000003306 136.0
HKD2_k127_9531807_121 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000012 138.0
HKD2_k127_9531807_122 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000000000000000000003983 127.0
HKD2_k127_9531807_123 TRANSCRIPTIONal - - - 0.000000000000000000000000000001745 125.0
HKD2_k127_9531807_124 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000000000000000000000000002219 122.0
HKD2_k127_9531807_125 - - - - 0.000000000000000000000000000005237 128.0
HKD2_k127_9531807_126 ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028,K08697 - - 0.000000000000000000000000000009562 121.0
HKD2_k127_9531807_127 Fatty acid hydroxylase superfamily K15746 - 1.14.15.24 0.00000000000000000000000000001079 124.0
HKD2_k127_9531807_128 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000002093 128.0
HKD2_k127_9531807_129 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000003689 126.0
HKD2_k127_9531807_13 Domain of unknown function (DUF5107) - - - 3.77e-234 760.0
HKD2_k127_9531807_130 PFAM 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.00000000000000000000000000003864 120.0
HKD2_k127_9531807_131 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000454 125.0
HKD2_k127_9531807_132 Glycoprotease family K14742 - - 0.000000000000000000000000000692 123.0
HKD2_k127_9531807_133 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000007537 115.0
HKD2_k127_9531807_134 Transposase K18827 - 2.1.1.294,2.7.1.181 0.000000000000000000000001965 114.0
HKD2_k127_9531807_135 ligase activity, forming carbon-carbon bonds K00627,K01960,K20140 - 2.3.1.12,6.4.1.1,6.4.1.7 0.0000000000000000000000119 105.0
HKD2_k127_9531807_136 - - - - 0.0000000000000000000001103 104.0
HKD2_k127_9531807_137 Carotenoid biosynthesis protein - - - 0.0000000000000000000001177 109.0
HKD2_k127_9531807_138 Outer membrane efflux protein - - - 0.000000000000000000002147 108.0
HKD2_k127_9531807_139 lactoylglutathione lyase activity - - - 0.00000000000000000002269 95.0
HKD2_k127_9531807_14 belongs to the aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 9.168e-230 719.0
HKD2_k127_9531807_140 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) - - - 0.000000000000000002238 87.0
HKD2_k127_9531807_141 lycopene cyclase - - - 0.000000000000000002445 94.0
HKD2_k127_9531807_142 PFAM regulatory protein, MerR K22491 - - 0.00000000000000007466 91.0
HKD2_k127_9531807_143 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000001204 82.0
HKD2_k127_9531807_144 - - - - 0.000000000000004342 87.0
HKD2_k127_9531807_145 Histidine Phosphotransfer domain K03407 - 2.7.13.3 0.000000000000006922 82.0
HKD2_k127_9531807_146 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000005852 84.0
HKD2_k127_9531807_147 - - - - 0.0000000000001412 79.0
HKD2_k127_9531807_148 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000002194 72.0
HKD2_k127_9531807_149 helix_turn_helix, Lux Regulon - - - 0.00000000003296 72.0
HKD2_k127_9531807_15 phosphorelay signal transduction system - - - 9.806e-222 699.0
HKD2_k127_9531807_150 Glycogen recognition site of AMP-activated protein kinase - - - 0.0000000001108 69.0
HKD2_k127_9531807_151 - - - - 0.00000000206 66.0
HKD2_k127_9531807_152 lycopene cyclase - - - 0.00000001317 64.0
HKD2_k127_9531807_153 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K04032 - 2.5.1.17 0.00000002091 59.0
HKD2_k127_9531807_154 Membrane-bound dehydrogenase domain - - - 0.0000000217 67.0
HKD2_k127_9531807_156 DNA-binding protein - - - 0.0002028 49.0
HKD2_k127_9531807_157 Putative zinc-finger - - - 0.0004377 51.0
HKD2_k127_9531807_16 Tricorn protease C1 domain K08676 - - 8.951e-208 686.0
HKD2_k127_9531807_17 PFAM Glycosyl hydrolase family 1 K05350 - 3.2.1.21 2.221e-206 651.0
HKD2_k127_9531807_18 Sulfate permease family K01673,K03321 - 4.2.1.1 7.593e-206 655.0
HKD2_k127_9531807_19 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 2.768e-202 643.0
HKD2_k127_9531807_2 AcrB/AcrD/AcrF family K07787,K15726 - - 0.0 1093.0
HKD2_k127_9531807_20 arginyl-tRNA aminoacylation K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.979e-202 646.0
HKD2_k127_9531807_21 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 629.0
HKD2_k127_9531807_22 Psort location Cytoplasmic, score - - - 7.821e-194 612.0
HKD2_k127_9531807_23 Peptidase M1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 611.0
HKD2_k127_9531807_24 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 608.0
HKD2_k127_9531807_25 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 608.0
HKD2_k127_9531807_26 acetate kinase activity K00925,K19697 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1,2.7.2.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 561.0
HKD2_k127_9531807_27 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 553.0
HKD2_k127_9531807_28 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 543.0
HKD2_k127_9531807_29 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 550.0
HKD2_k127_9531807_3 FAD linked oxidase domain protein K18930 - - 0.0 1080.0
HKD2_k127_9531807_30 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 550.0
HKD2_k127_9531807_31 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 537.0
HKD2_k127_9531807_32 PFAM RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 512.0
HKD2_k127_9531807_33 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 513.0
HKD2_k127_9531807_34 PFAM aldo keto reductase K19265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 499.0
HKD2_k127_9531807_35 Converts alpha-aldose to the beta-anomer K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 491.0
HKD2_k127_9531807_36 Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 481.0
HKD2_k127_9531807_37 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 475.0
HKD2_k127_9531807_38 PFAM amine oxidase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 480.0
HKD2_k127_9531807_39 pyrroloquinoline quinone binding K00117 - 1.1.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 469.0
HKD2_k127_9531807_4 N-Acetylmuramoyl-L-alanine amidase - - - 2.784e-290 924.0
HKD2_k127_9531807_40 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 461.0
HKD2_k127_9531807_41 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 454.0
HKD2_k127_9531807_42 GHMP kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 449.0
HKD2_k127_9531807_43 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 448.0
HKD2_k127_9531807_44 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 447.0
HKD2_k127_9531807_45 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 432.0
HKD2_k127_9531807_46 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 442.0
HKD2_k127_9531807_47 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 423.0
HKD2_k127_9531807_48 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 404.0
HKD2_k127_9531807_49 Class ii aldolase K01628,K03077,K11216 - 2.7.1.189,4.1.2.17,5.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 393.0
HKD2_k127_9531807_5 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 9.314e-290 907.0
HKD2_k127_9531807_50 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 405.0
HKD2_k127_9531807_51 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 395.0
HKD2_k127_9531807_52 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 397.0
HKD2_k127_9531807_53 Belongs to the LDH MDH superfamily K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 380.0
HKD2_k127_9531807_54 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 381.0
HKD2_k127_9531807_55 Aldo Keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 369.0
HKD2_k127_9531807_56 Pyridoxal-phosphate dependent enzyme K05396,K17950 - 4.4.1.15,4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 364.0
HKD2_k127_9531807_57 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007095 358.0
HKD2_k127_9531807_58 Amino acid permease K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 357.0
HKD2_k127_9531807_59 transglutaminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 350.0
HKD2_k127_9531807_6 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 2.933e-279 877.0
HKD2_k127_9531807_60 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 336.0
HKD2_k127_9531807_61 PhoQ Sensor K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 346.0
HKD2_k127_9531807_62 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 331.0
HKD2_k127_9531807_63 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 331.0
HKD2_k127_9531807_64 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
HKD2_k127_9531807_65 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 328.0
HKD2_k127_9531807_66 Putative methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 327.0
HKD2_k127_9531807_67 PFAM glycosyl transferase family 2 K14597 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 327.0
HKD2_k127_9531807_68 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 328.0
HKD2_k127_9531807_69 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 307.0
HKD2_k127_9531807_7 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01848 - 5.4.99.2 1.254e-267 835.0
HKD2_k127_9531807_70 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 312.0
HKD2_k127_9531807_71 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 296.0
HKD2_k127_9531807_72 propanediol catabolic process K15024 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 290.0
HKD2_k127_9531807_73 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 288.0
HKD2_k127_9531807_74 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 291.0
HKD2_k127_9531807_75 queuosine metabolic process K04068,K10026 - 1.97.1.4,4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001528 264.0
HKD2_k127_9531807_76 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000002498 269.0
HKD2_k127_9531807_77 Alpha/beta hydrolase family K01175 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008247 265.0
HKD2_k127_9531807_78 undecaprenyl-diphosphatase activity K06153 GO:0006950,GO:0008150,GO:0050896,GO:0051409 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000003427 267.0
HKD2_k127_9531807_79 polysaccharide catabolic process K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000003862 269.0
HKD2_k127_9531807_8 Glycosyl hydrolases family 38 N-terminal domain - - - 2.875e-264 852.0
HKD2_k127_9531807_80 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000004284 261.0
HKD2_k127_9531807_81 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005123 261.0
HKD2_k127_9531807_82 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
HKD2_k127_9531807_83 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 256.0
HKD2_k127_9531807_84 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001509 255.0
HKD2_k127_9531807_85 Belongs to the peptidase S8 family K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001117 250.0
HKD2_k127_9531807_86 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000006575 252.0
HKD2_k127_9531807_87 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000378 245.0
HKD2_k127_9531807_88 D-lyxose isomerase K09988 - 5.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000001521 237.0
HKD2_k127_9531807_89 Pseudouridine synthase K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000006981 239.0
HKD2_k127_9531807_9 Pyruvate formate lyase-like - - - 1.383e-244 776.0
HKD2_k127_9531807_90 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000002947 228.0
HKD2_k127_9531807_91 ABC transporter (Permease K02026 - - 0.0000000000000000000000000000000000000000000000000000000000001202 226.0
HKD2_k127_9531807_92 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000000000000000000000000000005985 213.0
HKD2_k127_9531807_93 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000006432 218.0
HKD2_k127_9531807_94 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000863 217.0
HKD2_k127_9531807_95 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000001901 213.0
HKD2_k127_9531807_96 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000003629 216.0
HKD2_k127_9531807_97 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000005531 203.0
HKD2_k127_9531807_98 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000004576 206.0
HKD2_k127_9531807_99 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000567 211.0
HKD2_k127_9785958_0 Glycosyl hydrolases family 2 - - - 5.049e-287 912.0
HKD2_k127_9785958_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 5.426e-245 772.0
HKD2_k127_9785958_10 Phospholipase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 587.0
HKD2_k127_9785958_11 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 534.0
HKD2_k127_9785958_12 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 527.0
HKD2_k127_9785958_13 BNR repeat-like domain K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 473.0
HKD2_k127_9785958_14 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 441.0
HKD2_k127_9785958_15 response regulator K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 446.0
HKD2_k127_9785958_16 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 437.0
HKD2_k127_9785958_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 437.0
HKD2_k127_9785958_18 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 444.0
HKD2_k127_9785958_19 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 444.0
HKD2_k127_9785958_2 - - - - 2.079e-244 779.0
HKD2_k127_9785958_20 PFAM Alcohol dehydrogenase, zinc-binding K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 415.0
HKD2_k127_9785958_21 transferase activity, transferring glycosyl groups K18785 - 2.4.1.319,2.4.1.320 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 399.0
HKD2_k127_9785958_22 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 385.0
HKD2_k127_9785958_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 378.0
HKD2_k127_9785958_24 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 367.0
HKD2_k127_9785958_25 Thioredoxin reductase K07222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 363.0
HKD2_k127_9785958_26 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 355.0
HKD2_k127_9785958_27 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 357.0
HKD2_k127_9785958_28 Fe-S cluster domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 359.0
HKD2_k127_9785958_29 COG2211 Na melibiose symporter and related transporters K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 341.0
HKD2_k127_9785958_3 Alpha-L-arabinofuranosidase domain protein K01209 - 3.2.1.55 1.874e-241 756.0
HKD2_k127_9785958_30 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 304.0
HKD2_k127_9785958_31 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003119 275.0
HKD2_k127_9785958_32 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003486 253.0
HKD2_k127_9785958_33 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001925 249.0
HKD2_k127_9785958_34 Chalcone and stilbene synthases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007725 250.0
HKD2_k127_9785958_35 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.000000000000000000000000000000000000000000000000000000000000000003631 235.0
HKD2_k127_9785958_36 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004338 231.0
HKD2_k127_9785958_37 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000004602 220.0
HKD2_k127_9785958_38 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000006759 221.0
HKD2_k127_9785958_39 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000009446 224.0
HKD2_k127_9785958_4 Nickel-dependent hydrogenase K14126 - 1.8.98.5 6.481e-236 737.0
HKD2_k127_9785958_40 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000008292 217.0
HKD2_k127_9785958_41 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000002229 210.0
HKD2_k127_9785958_42 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000003892 202.0
HKD2_k127_9785958_43 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000001193 203.0
HKD2_k127_9785958_44 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000009951 199.0
HKD2_k127_9785958_45 - - - - 0.00000000000000000000000000000000000000000000000494 176.0
HKD2_k127_9785958_46 SMART ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000006531 176.0
HKD2_k127_9785958_47 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000001087 174.0
HKD2_k127_9785958_48 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000001342 168.0
HKD2_k127_9785958_49 Uncharacterized protein conserved in bacteria (DUF2087) - - - 0.00000000000000000000000000000000000000000004092 164.0
HKD2_k127_9785958_5 symporter activity K03307 - - 6.229e-234 743.0
HKD2_k127_9785958_50 YCII-related domain - - - 0.00000000000000000000000000000000000000000008747 166.0
HKD2_k127_9785958_51 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000001151 163.0
HKD2_k127_9785958_52 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000006248 174.0
HKD2_k127_9785958_53 - - - - 0.000000000000000000000000000000000000000006491 160.0
HKD2_k127_9785958_54 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000792 174.0
HKD2_k127_9785958_55 sigma factor antagonist activity K03458,K04757 - 2.7.11.1 0.00000000000000000000000000000000000000001134 158.0
HKD2_k127_9785958_56 FR47-like protein - - - 0.00000000000000000000000000000000000000004763 158.0
HKD2_k127_9785958_57 Methyltransferase - - - 0.0000000000000000000000000000000000000002378 161.0
HKD2_k127_9785958_58 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000002049 152.0
HKD2_k127_9785958_59 FAD binding domain - - - 0.0000000000000000000000000000000007855 146.0
HKD2_k127_9785958_6 radical SAM domain protein - - - 7.085e-213 673.0
HKD2_k127_9785958_60 nitrogen regulatory protein P-II - - - 0.000000000000000000000000000000004857 135.0
HKD2_k127_9785958_61 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000001445 128.0
HKD2_k127_9785958_62 DRTGG domain - - - 0.0000000000000000000000000001101 119.0
HKD2_k127_9785958_63 DRTGG domain - - - 0.00000000000000000000000002297 112.0
HKD2_k127_9785958_64 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000006117 109.0
HKD2_k127_9785958_65 Hydrogenase maturation protease K03605 - - 0.00000000000000000000357 103.0
HKD2_k127_9785958_66 Domain of unknown function (DUF4177) - - - 0.00000000000001256 75.0
HKD2_k127_9785958_67 transcriptional - - - 0.000006088 55.0
HKD2_k127_9785958_68 Alpha/beta hydrolase family - - - 0.00012 49.0
HKD2_k127_9785958_69 BlaR1 peptidase M56 - - - 0.0002362 49.0
HKD2_k127_9785958_7 Domain of unknown function (DUF4070) - - - 9.632e-201 636.0
HKD2_k127_9785958_8 Alpha-L-fucosidase K01206 - 3.2.1.51 6.276e-200 631.0
HKD2_k127_9785958_9 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 612.0